{"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:1902115", "l": "regulation of organelle assembly", "d": ["Any process that modulates the frequency, rate or extent of organelle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032491", "l": "detection of molecule of fungal origin", "d": ["The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106247", "l": "negative regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0030852", "l": "regulation of granulocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of granulocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021809", "l": "neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration", "d": ["Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048327", "l": "axial mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060291", "l": "long-term synaptic potentiation", "d": ["A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072189", "l": "ureter development", "d": ["The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. 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A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106427", "l": "negative regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043181", "l": "vacuolar sequestering", "d": ["The process of transporting a substance into, and confining within, a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0071900", "l": "regulation of protein serine/threonine kinase activity", "d": ["Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042796", "l": "snRNA transcription by RNA polymerase III", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900874", "l": "heptadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving heptadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0005993", "l": "trehalose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007181", "l": "transforming growth factor beta receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904968", "l": "positive regulation of spindle attachment to meiosis I kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030652", "l": "peptide antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2001014", "l": "regulation of skeletal muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021997", "l": "neural plate axis specification", "d": ["The pattern specification process in which the axes of the nervous system are established."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060943", "l": "neural crest-derived cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060754", "l": "positive regulation of mast cell chemotaxis", "d": ["Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019619", "l": "3,4-dihydroxybenzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.594400196502249", "identifiers": [{"i": "GO:0010562", "l": "positive regulation of phosphorus metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008635", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001007", "l": "negative regulation of cellulose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090349", "l": "negative regulation of cellular organohalogen metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0106030", "l": "neuron projection fasciculation", "d": ["The collection of neuronal projections into a bundle of rods, known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031443", "l": "fast-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000371", "l": "regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900900", "l": "negative regulation of heptadecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0009065", "l": "glutamine family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905052", "l": "negative regulation of base-excision repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0008215", "l": "spermine metabolic process", "d": ["The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002826", "l": "negative regulation of T-helper 1 type immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0002712", "l": "regulation of B cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of B cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001177", "l": "regulation of transcription open complex formation at RNA polymerase II promoter", "d": ["Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000639", "l": "negative regulation of SREBP signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903748", "l": "negative regulation of establishment of protein localization to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0034311", "l": "diol metabolic process", "d": ["The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046957", "l": "negative phototaxis", "d": ["The directed movement of a cell or organism away from a source of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1903335", "l": "regulation of vacuolar transport", "d": ["Any process that modulates the frequency, rate or extent of vacuolar transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045702", "l": "positive regulation of spermatid nuclear differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043272", "l": "ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009187", "l": "cyclic nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048109", "l": "peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070801", "l": "positive regulation of conidiophore stalk development", "d": ["Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900937", "l": "positive regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110138", "l": "positive regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904301", "l": "regulation of maternal process involved in parturition", "d": ["Any process that modulates the frequency, rate or extent of maternal process involved in parturition."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0061709", "l": "reticulophagy", "d": ["The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043152", "l": "induction of bacterial agglutination", "d": ["Any process in which infecting bacteria are clumped together by a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032780", "l": "negative regulation of ATP-dependent activity", "d": ["Any process that stops or reduces the rate of an ATP-dependent activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031272", "l": "regulation of pseudopodium assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of pseudopodia."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0033374", "l": "protein localization to T cell secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048304", "l": "positive regulation of isotype switching to IgG isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901977", "l": "negative regulation of cell cycle checkpoint", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003070", "l": "regulation of systemic arterial blood pressure by neurotransmitter", "d": ["The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021804", "l": "negative regulation of cell adhesion in ventricular zone", "d": ["The process that results in the loss of attachments of a cell in the ventricular zone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014034", "l": "neural crest cell fate commitment", "d": ["The process in which a cell becomes committed to become a neural crest cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000768", "l": "positive regulation of nephron tubule epithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003162", "l": "atrioventricular node development", "d": ["The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000711", "l": "meiotic DNA repair synthesis", "d": ["During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001794", "l": "type IIa hypersensitivity", "d": ["An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905930", "l": "regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006285", "l": "base-excision repair, AP site formation", "d": ["The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901257", "l": "negative regulation of macrophage colony-stimulating factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061670", "l": "evoked neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905429", "l": "response to glycine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0051653", "l": "spindle localization", "d": ["Any process in which is the spindle is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090052", "l": "regulation of pericentric heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of heterochromatin formation at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032333", "l": "activin secretion", "d": ["The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905000", "l": "regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0071363", "l": "cellular response to growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905683", "l": "peroxisome disassembly", "d": ["The disaggregation of a peroxisome into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0015891", "l": "siderophore transport", "d": ["The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080005", "l": "photosystem stoichiometry adjustment", "d": ["Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001213", "l": "negative regulation of vasculogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072138", "l": "mesenchymal cell proliferation involved in ureteric bud development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:0032881", "l": "regulation of polysaccharide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904241", "l": "positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0017003", "l": "protein-heme linkage", "d": ["The covalent linkage of heme and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072085", "l": "specification of connecting tubule identity", "d": ["The process in which the connecting tubule of the kidney nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000882", "l": "negative regulation of starch catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000595", "l": "regulation of optic nerve formation", "d": ["Any process that modulates the frequency, rate or extent of optic nerve formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902217", "l": "erythrocyte apoptotic process", "d": ["Any apoptotic process in an erythrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046088", "l": "cytidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0061951", "l": "establishment of protein localization to plasma membrane", "d": ["The directed movement of a protein to a specific location in a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015759", "l": "beta-glucoside transport", "d": ["The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046191", "l": "aerobic phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036351", "l": "histone H2A-K13 ubiquitination", "d": ["The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901246", "l": "regulation of lung ciliated cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060678", "l": "dichotomous subdivision of terminal units involved in ureteric bud branching", "d": ["The process in which a ureteric bud bifurcates at its end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901411", "l": "negative regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905487", "l": "negative regulation of anterior/posterior axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070255", "l": "regulation of mucus secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019387", "l": "methanogenesis, from methanol", "d": ["The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042548", "l": "regulation of photosynthesis, light reaction", "d": ["Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090321", "l": "positive regulation of chylomicron remnant clearance", "d": ["Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903360", "l": "protein localization to lateral cortical node", "d": ["A process in which a protein is transported to, or maintained in, a location within a lateral cortical node."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902725", "l": "negative regulation of satellite cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030474", "l": "spindle pole body duplication", "d": ["Construction of a new spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034476", "l": "U5 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U5 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021692", "l": "cerebellar Purkinje cell layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070795", "l": "positive regulation of conidiophore development", "d": ["Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0140278", "l": "mitotic division septum assembly", "d": ["The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071725", "l": "response to triacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.652206388559449", "identifiers": [{"i": "GO:0009112", "l": "nucleobase metabolic process", "d": ["The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903519", "l": "regulation of mammary gland involution", "d": ["Any process that modulates the frequency, rate or extent of mammary gland involution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002734", "l": "negative regulation of myeloid dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043697", "l": "cell dedifferentiation", "d": ["The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048400", "l": "positive regulation of intermediate mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042309", "l": "homoiothermy", "d": ["Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097166", "l": "lens epithelial cell proliferation", "d": ["The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050836", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070729", "l": "cyclic nucleotide transport", "d": ["The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904786", "l": "negative regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006783", "l": "heme biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002572", "l": "pro-T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010381", "l": "peroxisome-chloroplast membrane tethering", "d": ["The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905807", "l": "negative regulation of synapse pruning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032891", "l": "negative regulation of organic acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031447", "l": "negative regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010286", "l": "heat acclimation", "d": ["Any process that increases heat tolerance of an organism in response to high temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032721", "l": "negative regulation of lymphotoxin A production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902918", "l": "poly(5-hydroxyvalerate) metabolic process", "d": ["The chemical reactions and pathways involving poly(5-hydroxyvalerate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904472", "l": "positive regulation of endothelin production", "d": ["Any process that activates or increases the frequency, rate or extent of endothelin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003342", "l": "proepicardium development", "d": ["The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072735", "l": "response to tert-butyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061222", "l": "mesonephric mesenchymal cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0014029", "l": "neural crest formation", "d": ["The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904340", "l": "positive regulation of dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034510", "l": "centromere separation", "d": ["The cell cycle process in which centromeres are physically detached from each other during chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0032200", "l": "telomere organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021598", "l": "abducens nerve morphogenesis", "d": ["The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097751", "l": "spore-bearing structure formation", "d": ["The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0002645", "l": "positive regulation of tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900385", "l": "negative regulation of flavonol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006014", "l": "D-ribose metabolic process", "d": ["The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.9193264281678", "identifiers": [{"i": "GO:0098916", "l": "anterograde trans-synaptic signaling", "d": ["Cell-cell signaling from pre to post-synapse, across the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000703", "l": "negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1990709", "l": "presynaptic active zone organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051593", "l": "response to folic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0060232", "l": "delamination", "d": ["The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072713", "l": "cellular response to thiabendazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002340", "l": "central B cell selection", "d": ["Any B cell selection process that occurs in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990048", "l": "anterograde neuronal dense core vesicle transport", "d": ["The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001124", "l": "regulation of translational frameshifting", "d": ["Any process that modulates the frequency, rate or extent of translational frameshifting."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019694", "l": "alkanesulfonate metabolic process", "d": ["The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051522", "l": "activation of monopolar cell growth", "d": ["Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904297", "l": "positive regulation of osmolarity-sensing cation channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000115", "l": "regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031455", "l": "glycine betaine metabolic process", "d": ["The chemical reactions and pathways involving glycine betaine, N-trimethylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070150", "l": "mitochondrial glycyl-tRNA aminoacylation", "d": ["The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990619", "l": "histone H3-K9 deacetylation", "d": ["The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904509", "l": "negative regulation of protein localization to basolateral plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900224", "l": "positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018950", "l": "o-xylene metabolic process", "d": ["The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035269", "l": "protein O-linked mannosylation", "d": ["The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061307", "l": "cardiac neural crest cell differentiation involved in heart development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0046128", "l": "purine ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043518", "l": "negative regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901370", "l": "response to glutathione", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010544", "l": "negative regulation of platelet activation", "d": ["Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090691", "l": "formation of plant organ boundary", "d": ["The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009269", "l": "response to desiccation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060866", "l": "leaf abscission", "d": ["The controlled shedding of a leaf."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904736", "l": "negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044278", "l": "disruption of cell wall in another organism", "d": ["The disruption of the cell wall of another organism, leading to damage or temporary subversion of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018142", "l": "protein-DNA covalent cross-linking", "d": ["The formation of a covalent cross-link between DNA and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061744", "l": "motor behavior", "d": ["The specific neuromuscular movement of a single organism in response to external or internal stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046400", "l": "keto-3-deoxy-D-manno-octulosonic acid metabolic process", "d": ["The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032490", "l": "detection of molecule of bacterial origin", "d": ["The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060948", "l": "cardiac vascular smooth muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019696", "l": "toluene oxidation via toluene-cis-1,2-dihydrodiol", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:1903707", "l": "negative regulation of hemopoiesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046745", "l": "viral capsid secondary envelopment", "d": ["The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039009", "l": "rectal diverticulum development", "d": ["The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051481", "l": "negative regulation of cytosolic calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000174", "l": "regulation of pro-T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pro-T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000740", "l": "nuclear membrane fusion", "d": ["The joining of 2 or more lipid bilayer membranes that surround the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000324", "l": "positive regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061287", "l": "mesonephric capsule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000533", "l": "negative regulation of renal albumin absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905797", "l": "negative regulation of intraciliary anterograde transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043941", "l": "positive regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905353", "l": "ciliary transition fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060435", "l": "bronchiole development", "d": ["The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001896", "l": "autolysis", "d": ["A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006990", "l": "positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response", "d": ["The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903776", "l": "regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140052", "l": "cellular response to oxidised low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060332", "l": "positive regulation of response to type II interferon", "d": ["Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036371", "l": "protein localization to T-tubule", "d": ["A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021658", "l": "rhombomere 3 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001983", "l": "baroreceptor response to increased systemic arterial blood pressure", "d": ["The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060748", "l": "tertiary branching involved in mammary gland duct morphogenesis", "d": ["The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039010", "l": "specification of pronephric distal tubule identity", "d": ["The process in which the distal tubule of the pronephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900246", "l": "positive regulation of RIG-I signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106236", "l": "rhamnolipid biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.896818514898158", "identifiers": [{"i": "GO:0008104", "l": "protein localization", "d": ["Any process in which a protein is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900970", "l": "positive regulation of sarcinapterin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901833", "l": "all-trans-neoxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070076", "l": "histone lysine demethylation", "d": ["The modification of a histone by the removal of a methyl group from a lysine residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905689", "l": "positive regulation of diacylglycerol kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060129", "l": "thyroid-stimulating hormone-secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002372", "l": "myeloid dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a myeloid dendritic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021834", "l": "chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901203", "l": "positive regulation of extracellular matrix assembly", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903569", "l": "positive regulation of protein localization to ciliary membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0101030", "l": "tRNA-guanine transglycosylation", "d": ["The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051111", "l": "peptidyl-histidine adenylylation", "d": ["The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032622", "l": "interleukin-19 production", "d": ["The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000557", "l": "regulation of immunoglobulin production in mucosal tissue", "d": ["Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "31.880931590405361", "identifiers": [{"i": "GO:0051301", "l": "cell division", "d": ["The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015770", "l": "sucrose transport", "d": ["The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990172", "l": "G protein-coupled receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071764", "l": "nuclear outer membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035593", "l": "positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region", "d": ["Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043617", "l": "cellular response to sucrose starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905821", "l": "positive regulation of chromosome condensation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044514", "l": "envenomation resulting in positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0070091", "l": "glucagon secretion", "d": ["The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0055008", "l": "cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of cardiac muscle tissue are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003111", "l": "positive regulation of heart rate by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0061242", "l": "mesonephric nephron tubule development", "d": ["The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904027", "l": "negative regulation of collagen fibril organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000536", "l": "negative regulation of entry of bacterium into host cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044582", "l": "butyryl-CoA catabolic process to butanol", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046002", "l": "positive regulation of preblastoderm mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002093", "l": "auditory receptor cell morphogenesis", "d": ["Any process that alters the size or shape of an auditory receptor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032703", "l": "negative regulation of interleukin-2 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905522", "l": "negative regulation of macrophage migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031104", "l": "dendrite regeneration", "d": ["The regrowth of dendrites in response to their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071645", "l": "positive regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0051148", "l": "negative regulation of muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0050864", "l": "regulation of B cell activation", "d": ["Any process that modulates the frequency, rate or extent of B cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140979", "l": "intracellular nucleotide homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035077", "l": "ecdysone-mediated polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905715", "l": "regulation of cornification", "d": ["Any process that modulates the frequency, rate or extent of cornification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090336", "l": "positive regulation of brown fat cell differentiation", "d": ["Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042400", "l": "ectoine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0001759", "l": "organ induction", "d": ["The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051385", "l": "response to mineralocorticoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015830", "l": "diaminopimelate transport", "d": ["The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045818", "l": "negative regulation of glycogen catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901457", "l": "regulation of response to acetate", "d": ["Any process that modulates the frequency, rate or extent of response to acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021631", "l": "optic nerve morphogenesis", "d": ["The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903775", "l": "regulation of DNA double-strand break processing", "d": ["Any process that modulates the frequency, rate or extent of DNA double-strand break processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903795", "l": "regulation of inorganic anion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035137", "l": "hindlimb morphogenesis", "d": ["The process in which the anatomical structures of the hindlimb are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043557", "l": "regulation of translation in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046967", "l": "cytosol to endoplasmic reticulum transport", "d": ["The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021713", "l": "inferior olivary nucleus development", "d": ["The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007228", "l": "positive regulation of hh target transcription factor activity", "d": ["Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902364", "l": "negative regulation of protein localization to spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002008", "l": "excitation of vasomotor center by chemoreceptor signaling", "d": ["The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072695", "l": "regulation of DNA recombination at telomere", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination within the telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033394", "l": "beta-alanine biosynthetic process via 1,3 diaminopropane", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180015", "l": "nucleoside import across plasma membrane", "d": ["The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110023", "l": "negative regulation of cardiac muscle myoblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900599", "l": "demethylkotanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of demethylkotanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046786", "l": "viral replication complex formation and maintenance", "d": ["The process of organizing and assembling viral replication proteins in preparation for viral replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001878", "l": "response to yeast", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060101", "l": "negative regulation of phagocytosis, engulfment", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061051", "l": "positive regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033354", "l": "chlorophyll cycle", "d": ["A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140504", "l": "microlipophagy", "d": ["Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0062237", "l": "protein localization to postsynapse", "d": ["Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075243", "l": "oospore formation", "d": ["The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900696", "l": "negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033054", "l": "D-glutamate metabolic process", "d": ["The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000363", "l": "positive regulation of prostaglandin-E synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010754", "l": "negative regulation of cGMP-mediated signaling", "d": ["Any process that decreases the rate, frequency or extent of cGMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098039", "l": "replicative DNA transposition", "d": ["Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031553", "l": "positive regulation of brain-derived neurotrophic factor-activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039580", "l": "suppression by virus of host PKR signaling", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha, inhibiting protein synthesis as an antiviral response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060596", "l": "mammary placode formation", "d": ["The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018428", "l": "copper incorporation into copper-sulfur cluster", "d": ["The incorporation of copper into a copper-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0043502", "l": "regulation of muscle adaptation", "d": ["Any process that modulates the frequency, rate or extent of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061277", "l": "mesonephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006552", "l": "leucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905736", "l": "negative regulation of L-proline import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900983", "l": "vindoline metabolic process", "d": ["The chemical reactions and pathways involving vindoline."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046504", "l": "glycerol ether biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0052111", "l": "disruption by symbiont of host anatomical structure", "d": ["The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150070", "l": "regulation of arginase activity", "d": ["Any process that modulates the frequency, rate or extent of arginase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060253", "l": "negative regulation of glial cell proliferation", "d": ["Any process that stops or decreases the rate or extent of glial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098628", "l": "peptidyl-N-phospho-arginine dephosphorylation", "d": ["The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046402", "l": "O antigen metabolic process", "d": ["The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0009620", "l": "response to fungus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060219", "l": "camera-type eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071274", "l": "isoquinoline alkaloid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900217", "l": "regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901928", "l": "cadinene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cadinene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071388", "l": "cellular response to cortisone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905296", "l": "negative regulation of neural crest cell fate specification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036511", "l": "trimming of first mannose on A branch", "d": ["The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046499", "l": "S-adenosylmethioninamine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051521", "l": "termination of monopolar cell growth", "d": ["Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000301", "l": "retrograde transport, vesicle recycling within Golgi", "d": ["The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903785", "l": "L-valine transmembrane transport", "d": ["The directed movement of L-valine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051027", "l": "DNA transport", "d": ["The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0000916", "l": "actomyosin contractile ring contraction", "d": ["The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097497", "l": "blood vessel endothelial cell delamination", "d": ["The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061260", "l": "mesonephric mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000216", "l": "positive regulation of proline metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proline metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140969", "l": "determination of lung left/right asymmetry", "d": ["Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110025", "l": "DNA strand resection involved in replication fork processing", "d": ["The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0045893", "l": "positive regulation of DNA-templated transcription", "d": ["Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032749", "l": "positive regulation of interleukin-25 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-25 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903342", "l": "negative regulation of meiotic DNA double-strand break formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0007159", "l": "leukocyte cell-cell adhesion", "d": ["The attachment of a leukocyte to another cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0070914", "l": "UV-damage excision repair", "d": ["A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904872", "l": "regulation of telomerase RNA localization to Cajal body", "d": ["Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098792", "l": "xenophagy", "d": ["The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:1902414", "l": "protein localization to cell junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141009", "l": "piRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a piRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035494", "l": "SNARE complex disassembly", "d": ["The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904415", "l": "regulation of xenophagy", "d": ["Any process that modulates the frequency, rate or extent of xenophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003326", "l": "pancreatic A cell fate commitment", "d": ["The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902244", "l": "cis-abienol metabolic process", "d": ["The chemical reactions and pathways involving cis-abienol."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.937454763326897", "identifiers": [{"i": "GO:0098773", "l": "skin epidermis development", "d": ["The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019611", "l": "4-toluenecarboxylate metabolic process", "d": ["The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048920", "l": "posterior lateral line neuromast primordium migration", "d": ["The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045492", "l": "xylan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903897", "l": "regulation of PERK-mediated unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.514856771201437", "identifiers": [{"i": "GO:0033044", "l": "regulation of chromosome organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021607", "l": "accessory nerve morphogenesis", "d": ["The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097338", "l": "response to clozapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031053", "l": "primary miRNA processing", "d": ["A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902809", "l": "regulation of skeletal muscle fiber differentiation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061619", "l": "glycolytic process from mannose through fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006027", "l": "glycosaminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1901879", "l": "regulation of protein depolymerization", "d": ["Any process that modulates the frequency, rate or extent of protein depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003311", "l": "pancreatic D cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903212", "l": "protein localization to mating-type region heterochromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007171", "l": "activation of transmembrane receptor protein tyrosine kinase activity", "d": ["Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019859", "l": "thymine metabolic process", "d": ["The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034333", "l": "adherens junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072125", "l": "negative regulation of glomerular mesangial cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900078", "l": "positive regulation of cellular response to insulin stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043584", "l": "nose development", "d": ["The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014845", "l": "stomach body smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904530", "l": "negative regulation of actin filament binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051319", "l": "G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.377477496085667", "identifiers": [{"i": "GO:0010467", "l": "gene expression", "d": ["The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048022", "l": "negative regulation of melanin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0032297", "l": "negative regulation of DNA-templated DNA replication initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021810", "l": "neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration", "d": ["Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072023", "l": "thick ascending limb development", "d": ["The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900063", "l": "regulation of peroxisome organization", "d": ["Any process that modulates the frequency, rate or extent of peroxisome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903896", "l": "positive regulation of IRE1-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009852", "l": "auxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0061045", "l": "negative regulation of wound healing", "d": ["Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000294", "l": "positive regulation of defecation", "d": ["Any process that activates or increases the frequency, rate or extent of defecation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120073", "l": "negative regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031222", "l": "arabinan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.561493752554874", "identifiers": [{"i": "GO:1903706", "l": "regulation of hemopoiesis", "d": ["Any process that modulates the frequency, rate or extent of hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905626", "l": "positive regulation of L-methionine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904343", "l": "positive regulation of colon smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071448", "l": "cellular response to alkyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0007560", "l": "imaginal disc morphogenesis", "d": ["The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900938", "l": "regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072675", "l": "osteoclast fusion", "d": ["The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035616", "l": "histone H2B conserved C-terminal lysine deubiquitination", "d": ["A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071578", "l": "zinc ion import across plasma membrane", "d": ["The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048136", "l": "male germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single male gonial founder cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051125", "l": "regulation of actin nucleation", "d": ["Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0042173", "l": "regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that modulates the frequency, rate or extent of spore formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090371", "l": "regulation of glycerol transport", "d": ["Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019567", "l": "arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901558", "l": "response to metformin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003190", "l": "atrioventricular valve formation", "d": ["The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031914", "l": "negative regulation of synaptic plasticity", "d": ["A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904348", "l": "negative regulation of small intestine smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033078", "l": "extrathymic T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000041", "l": "negative regulation of planar cell polarity pathway involved in axis elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052489", "l": "negative regulation by host of symbiont programmed cell death", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001807", "l": "regulation of type IV hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035583", "l": "sequestering of TGFbeta in extracellular matrix", "d": ["Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071414", "l": "cellular response to methotrexate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0001751", "l": "compound eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900817", "l": "ochratoxin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ochratoxin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071954", "l": "chemokine (C-C motif) ligand 11 production", "d": ["The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015777", "l": "teichoic acid transport", "d": ["The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061956", "l": "penetration of cumulus oophorus", "d": ["The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0044743", "l": "protein transmembrane import into intracellular organelle", "d": ["The directed movement of proteins into an intracellular organelle, across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006201", "l": "GMP catabolic process to IMP", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903487", "l": "regulation of lactation", "d": ["Any process that modulates the frequency, rate or extent of lactation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044488", "l": "modulation of voltage-gated sodium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000961", "l": "negative regulation of mitochondrial RNA catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.514856771201437", "identifiers": [{"i": "GO:0050900", "l": "leukocyte migration", "d": ["The movement of a leukocyte within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902919", "l": "poly(5-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010652", "l": "positive regulation of cell communication by chemical coupling", "d": ["Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060065", "l": "uterus development", "d": ["The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052482", "l": "defense response by cell wall thickening", "d": ["A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010459", "l": "negative regulation of heart rate", "d": ["Any process that stops, prevents or reduces the frequency or rate of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030091", "l": "protein repair", "d": ["The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0030258", "l": "lipid modification", "d": ["The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0044839", "l": "cell cycle G2/M phase transition", "d": ["The cell cycle process by which a cell in G2 phase commits to M phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902367", "l": "negative regulation of Notch signaling pathway involved in somitogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039527", "l": "disruption by virus of host TRAF-mediated signal transduction", "d": ["A process in which a virus interferes with, inhibits or stops TRAF-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904482", "l": "cellular response to tetrahydrofolate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.519451917212066", "identifiers": [{"i": "GO:0071674", "l": "mononuclear cell migration", "d": ["The movement of a mononuclear cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016475", "l": "detection of nuclear:cytoplasmic ratio", "d": ["The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051518", "l": "positive regulation of bipolar cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.9246167158351", "identifiers": [{"i": "GO:0003073", "l": "regulation of systemic arterial blood pressure", "d": ["The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900923", "l": "regulation of glycine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of glycine import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0010359", "l": "regulation of anion channel activity", "d": ["Any process that modulates the frequency, rate or extent of anion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903222", "l": "quinolinic acid transmembrane transport", "d": ["The process in which quinolinic acid is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900895", "l": "positive regulation of tridecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tridecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000497", "l": "positive regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902696", "l": "glycine catabolic process to isobutanol", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0048167", "l": "regulation of synaptic plasticity", "d": ["A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0010631", "l": "epithelial cell migration", "d": ["The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061250", "l": "mesonephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072030", "l": "short nephron development", "d": ["The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070499", "l": "exosporium assembly", "d": ["A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0017007", "l": "protein-bilin linkage", "d": ["The covalent linkage of bilin and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034036", "l": "purine ribonucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018152", "l": "peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006777", "l": "Mo-molybdopterin cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905955", "l": "negative regulation of endothelial tube morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901748", "l": "leukotriene D4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene D4."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000551", "l": "regulation of T-helper 2 cell cytokine production", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030047", "l": "actin modification", "d": ["Covalent modification of an actin molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000508", "l": "regulation of dendritic cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072069", "l": "DCT cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043124", "l": "negative regulation of canonical NF-kappaB signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.841543847919574", "identifiers": [{"i": "GO:0060485", "l": "mesenchyme development", "d": ["The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001833", "l": "inner cell mass cell proliferation", "d": ["The proliferation of cells in the inner cell mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075114", "l": "symbiont-mediated suppression of host transmembrane receptor-mediated signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045945", "l": "positive regulation of transcription by RNA polymerase III", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048210", "l": "Golgi vesicle fusion to target membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000690", "l": "regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904291", "l": "positive regulation of mitotic DNA damage checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072482", "l": "response to mitotic cell cycle spindle orientation checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034137", "l": "positive regulation of toll-like receptor 2 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045461", "l": "sterigmatocystin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035039", "l": "male pronucleus assembly", "d": ["The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140125", "l": "thiamine import across plasma membrane", "d": ["The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000629", "l": "negative regulation of miRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0035337", "l": "fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080187", "l": "floral organ senescence", "d": ["The last stage of flower development during which programmed degradation of macromolecules and nutrient recycling take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031441", "l": "negative regulation of mRNA 3'-end processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0032878", "l": "regulation of establishment or maintenance of cell polarity", "d": ["Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042104", "l": "positive regulation of activated T cell proliferation", "d": ["Any process that activates or increases the rate or extent of activated T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010049", "l": "acquisition of plant reproductive competence", "d": ["The process in which a plant acquires the ability to respond to a floral inductive signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060153", "l": "perturbation by virus of host cell cycle progression", "d": ["A process in which a virus interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001987", "l": "vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019302", "l": "D-ribose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901693", "l": "negative regulation of compound eye retinal cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061129", "l": "negative regulation of positive chemotaxis to cAMP by DIF-2", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070472", "l": "regulation of uterine smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061048", "l": "negative regulation of branching involved in lung morphogenesis", "d": ["Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900074", "l": "negative regulation of neuromuscular synaptic transmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1902667", "l": "regulation of axon guidance", "d": ["Any process that modulates the frequency, rate or extent of axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045669", "l": "positive regulation of osteoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of osteoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086044", "l": "atrial cardiac muscle cell to AV node cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901812", "l": "beta-carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001410", "l": "chlamydospore formation", "d": ["The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060239", "l": "positive regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the rate, frequency or extent of signal transduction involved in conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046286", "l": "flavonoid phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051596", "l": "methylglyoxal catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045690", "l": "positive regulation of antipodal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904829", "l": "regulation of aortic smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0045446", "l": "endothelial cell differentiation", "d": ["The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902976", "l": "premeiotic DNA replication preinitiation complex assembly", "d": ["Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014025", "l": "neural keel formation", "d": ["The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071698", "l": "olfactory placode development", "d": ["The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042255", "l": "ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the mature ribosome and of its subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009227", "l": "nucleotide-sugar catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000911", "l": "positive regulation of sterol import", "d": ["Any process that activates or increases the frequency, rate or extent of sterol import."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140213", "l": "negative regulation of long-chain fatty acid import into cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0045926", "l": "negative regulation of growth", "d": ["Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042935", "l": "achromobactin transport", "d": ["The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045006", "l": "DNA deamination", "d": ["The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016525", "l": "negative regulation of angiogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060766", "l": "negative regulation of androgen receptor signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032024", "l": "positive regulation of insulin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007520", "l": "myoblast fusion", "d": ["A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046253", "l": "anaerobic toluene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0001892", "l": "embryonic placenta development", "d": ["The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046226", "l": "coumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061614", "l": "miRNA transcription", "d": ["The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150202", "l": "negative regulation of transport across blood-brain barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.694708458300589", "identifiers": [{"i": "GO:0016477", "l": "cell migration", "d": ["The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097491", "l": "sympathetic neuron projection guidance", "d": ["The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010969", "l": "regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044469", "l": "envenomation resulting in positive regulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000868", "l": "negative regulation of estrone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030921", "l": "peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090449", "l": "phloem glucosinolate loading", "d": ["The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901431", "l": "regulation of response to cycloalkane", "d": ["Any process that modulates the frequency, rate or extent of response to cycloalkane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061329", "l": "Malpighian tubule principal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001081", "l": "nitrogen catabolite repression of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902699", "l": "pentose catabolic process to acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110137", "l": "regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001936", "l": "regulation of endothelial cell proliferation", "d": ["Any process that modulates the frequency, rate, or extent of endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0072273", "l": "metanephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the metanephric nephron are generated and organized. 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Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080040", "l": "positive regulation of cellular response to phosphate starvation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904425", "l": "negative regulation of GTP binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097238", "l": "cellular response to methylglyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0048278", "l": "vesicle docking", "d": ["The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106047", "l": "polyamine deacetylation", "d": ["The modification of acetylpolyamine by the removal of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905450", "l": "negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090390", "l": "phagosome acidification involved in apoptotic cell clearance", "d": ["Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075319", "l": "positive regulation of ascus development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0035176", "l": "social behavior", "d": ["Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070503", "l": "selenium-containing prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905781", "l": "negative regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000236", "l": "mitotic prometaphase", "d": ["The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903199", "l": "negative regulation of L-dopa decarboxylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008340", "l": "determination of adult lifespan", "d": ["The pathways that regulate the duration of the adult phase of the life-cycle of an animal."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000108", "l": "positive regulation of leukocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045687", "l": "positive regulation of glial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of glia cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019623", "l": "atrazine catabolic process to urea", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090677", "l": "reversible differentiation", "d": ["A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904847", "l": "regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904196", "l": "negative regulation of granulosa cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001121", "l": "coenzyme gamma-F420-2 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060188", "l": "regulation of protein desumoylation", "d": ["Any process that modulates the frequency, rate or extent of protein desumoylation. 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An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902155", "l": "regulation of response to G1 DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140357", "l": "heme export from vacuole to cytoplasm", "d": ["The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007553", "l": "regulation of ecdysteroid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0048599", "l": "oocyte development", "d": ["The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003192", "l": "mitral valve formation", "d": ["The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045039", "l": "protein insertion into mitochondrial inner membrane", "d": ["The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032130", "l": "medial membrane band assembly", "d": ["The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002656", "l": "negative regulation of tolerance induction to nonself antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904145", "l": "negative regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901997", "l": "negative regulation of indoleacetic acid biosynthetic process via tryptophan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0018106", "l": "peptidyl-histidine phosphorylation", "d": ["The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018268", "l": "GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046701", "l": "insecticide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902721", "l": "negative regulation of prolactin secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072699", "l": "protein localization to cortical microtubule cytoskeleton", "d": ["A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0072350", "l": "tricarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002391", "l": "platelet activating factor production involved in inflammatory response", "d": ["The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052320", "l": "positive regulation of phytoalexin metabolic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061804", "l": "mitotic spindle formation (spindle phase one)", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000132", "l": "establishment of mitotic spindle orientation", "d": ["A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045639", "l": "positive regulation of myeloid cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045844", "l": "positive regulation of striated muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007421", "l": "stomatogastric nervous system development", "d": ["The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070286", "l": "axonemal dynein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034484", "l": "raffinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072144", "l": "glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032607", "l": "interferon-alpha production", "d": ["The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051070", "l": "galactomannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034964", "l": "box H/ACA RNA processing", "d": ["Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006620", "l": "post-translational protein targeting to endoplasmic reticulum membrane", "d": ["The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021558", "l": "trochlear nerve development", "d": ["The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141007", "l": "siRNA-mediated retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a siRNA triggers heterochromatin assembly. 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This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097499", "l": "protein localization to non-motile cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a non-motile cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032659", "l": "regulation of interleukin-16 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-16 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904259", "l": "regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1990573", "l": "potassium ion import across plasma membrane", "d": ["The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014870", "l": "response to muscle inactivity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051215", "l": "RNAi-mediated antiviral immunity against DNA virus", "d": ["An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.139250066949501", "identifiers": [{"i": "GO:0007049", "l": "cell cycle", "d": ["The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033249", "l": "positive regulation of penicillin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031920", "l": "pyridoxal transport", "d": ["The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110126", "l": "phloem loading", "d": ["The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902014", "l": "poly(glycerol phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.371247962591667", "identifiers": [{"i": "GO:0044057", "l": "regulation of system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060495", "l": "cell-cell signaling involved in lung development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070843", "l": "misfolded protein transport", "d": ["The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032536", "l": "regulation of cell projection size", "d": ["A process that modulates the size of a cell projection."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901064", "l": "syringal lignin metabolic process", "d": ["The chemical reactions and pathways involving syringal lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000308", "l": "negative regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032430", "l": "positive regulation of phospholipase A2 activity", "d": ["Any process that activates or increases the activity of the enzyme phospholipase A2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019422", "l": "disproportionation of elemental sulfur", "d": ["The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042414", "l": "epinephrine metabolic process", "d": ["The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900235", "l": "negative regulation of Kit signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000645", "l": "negative regulation of receptor catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900237", "l": "positive regulation of induction of conjugation with cellular fusion", "d": ["Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015742", "l": "alpha-ketoglutarate transport", "d": ["The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1902932", "l": "positive regulation of alcohol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002206", "l": "gene conversion of immunoglobulin genes", "d": ["The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014877", "l": "response to muscle inactivity involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007284", "l": "spermatogonial cell division", "d": ["The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0120033", "l": "negative regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080165", "l": "callose deposition in phloem sieve plate", "d": ["Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904296", "l": "negative regulation of osmolarity-sensing cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002136", "l": "tRNA wobble base lysidine biosynthesis", "d": ["The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033234", "l": "negative regulation of protein sumoylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0034368", "l": "protein-lipid complex remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a protein-lipid complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000117", "l": "regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018386", "l": "N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine", "d": ["The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901320", "l": "negative regulation of heart induction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heart induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902511", "l": "negative regulation of apoptotic DNA fragmentation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002809", "l": "negative regulation of antibacterial peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900261", "l": "positive regulation of RNA-dependent RNA polymerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA 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"biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0002695", "l": "negative regulation of leukocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900611", "l": "F-9775A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of F-9775A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044735", "l": "envenomation resulting in negative regulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070572", "l": "positive regulation of neuron projection regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.949314868637913", "identifiers": [{"i": "GO:0006261", "l": "DNA-templated DNA replication", "d": ["A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0042310", "l": "vasoconstriction", "d": ["A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033023", "l": "mast cell homeostasis", "d": ["The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033986", "l": "response to methanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033091", "l": "positive regulation of immature T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of immature T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072145", "l": "proximal convoluted tubule segment 1 cell development", "d": ["The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072059", "l": "cortical collecting duct development", "d": ["The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014879", "l": "detection of electrical stimulus involved in regulation of muscle adaptation", "d": ["The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903488", "l": "negative regulation of lactation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lactation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905910", "l": "negative regulation of dauer entry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0060976", "l": "coronary vasculature development", "d": ["The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014826", "l": "vein smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034205", "l": "amyloid-beta formation", "d": ["The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900266", "l": "negative regulation of substance P receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046111", "l": "xanthine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901276", "l": "tartrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tartrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018934", "l": "nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048036", "l": "central complex development", "d": ["The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045019", "l": "negative regulation of nitric oxide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990384", "l": "hyaloid vascular plexus regression", "d": ["The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052777", "l": "diacetylchitobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0008366", "l": "axon ensheathment", "d": ["Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046090", "l": "deoxyadenosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045615", "l": "positive regulation of plasmatocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905624", "l": "regulation of L-methionine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045819", "l": "positive regulation of glycogen catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001782", "l": "B cell homeostasis", "d": ["The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901211", "l": "negative regulation of cardiac chamber formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097283", "l": "keratinocyte apoptotic process", "d": ["Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904754", "l": "positive regulation of vascular associated smooth muscle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000282", "l": "cellular bud site selection", "d": ["The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080142", "l": "regulation of salicylic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048084", "l": "positive regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030859", "l": "polarized epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0031056", "l": "regulation of histone modification", "d": ["Any process that modulates the frequency, rate or extent of the covalent alteration of a histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901666", "l": "positive regulation of NAD+ ADP-ribosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901756", "l": "butirosin metabolic process", "d": ["The chemical reactions and pathways involving butirosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0043403", "l": "skeletal muscle tissue regeneration", "d": ["The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001746", "l": "Bolwig's organ morphogenesis", "d": ["The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010593", "l": "negative regulation of lamellipodium assembly", "d": ["Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903380", "l": "positive regulation of mitotic chromosome condensation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051621", "l": "regulation of norepinephrine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990192", "l": "collecting lymphatic vessel constriction", "d": ["A decrease in the diameter of collecting lymphatic vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904831", "l": "positive regulation of aortic smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009446", "l": "putrescine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010738", "l": "regulation of protein kinase A signaling", "d": ["Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060375", "l": "regulation of mast cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904137", "l": "negative regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.629028984204552", "identifiers": [{"i": "GO:0000070", "l": "mitotic sister chromatid segregation", "d": ["The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033633", "l": "negative regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010779", "l": "meiotic DNA repair synthesis involved in meiotic gene conversion", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043131", "l": "erythrocyte enucleation", "d": ["The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090144", "l": "mitochondrial nucleoid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007156", "l": "homophilic cell adhesion via plasma membrane adhesion molecules", "d": ["The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051456", "l": "attachment of meiotic spindle microtubules to meiosis II kinetochore", "d": ["The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140729", "l": "self-resistance to endogenously produced metabolite", "d": ["A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060482", "l": "lobar bronchus development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046603", "l": "negative regulation of mitotic centrosome separation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072410", "l": "response to meiotic cell cycle checkpoint signaling", "d": ["A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006965", "l": "positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0010508", "l": "positive regulation of autophagy", "d": ["Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006384", "l": "transcription initiation at RNA polymerase III promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018172", "l": "peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039576", "l": "disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity", "d": ["Any process in which interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006572", "l": "tyrosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000852", "l": "regulation of corticosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062231", "l": "positive regulation of larval somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of larval somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060238", "l": "regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070309", "l": "lens fiber cell morphogenesis", "d": ["The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009962", "l": "regulation of flavonoid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140880", "l": "terrein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904656", "l": "regulation of sensory perception of sweet taste", "d": ["Any process that modulates the frequency, rate or extent of sensory perception of sweet taste."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070135", "l": "beta-1,2-oligomannoside metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901776", "l": "mitomycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mitomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061705", "l": "sucrose catabolic process to fructose-6-phosphate through glucose and fructose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051204", "l": "protein insertion into mitochondrial membrane", "d": ["The process that results in the incorporation of a protein into a mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007554", "l": "regulation of ecdysteroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141074", "l": "symbiont-mediated suppression of host cGAS-STING signal transduction", "d": ["A process in which a virus interferes with, inhibits or disrupt a cGAS/STING signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010495", "l": "siRNA-mediated long-distance post-transcriptional gene silencing", "d": ["An siRNA-mediated posttranscriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs, and in which the silencing signal originates in one tissue and occurs in a different tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014835", "l": "myoblast differentiation involved in skeletal muscle regeneration", "d": ["The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000874", "l": "regulation of glyoxylate cycle", "d": ["Any process that modulates the frequency, rate or extent of glyoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071793", "l": "bacillithiol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051386", "l": "regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002014", "l": "vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure", "d": ["The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905873", "l": "positive regulation of protein localization to cell leading edge", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072293", "l": "specification of metanephric nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036262", "l": "granulysin production", "d": ["The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002829", "l": "negative regulation of type 2 immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034079", "l": "butanediol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0035082", "l": "axoneme assembly", "d": ["The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900517", "l": "positive regulation of xylose catabolic process to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904816", "l": "positive regulation of protein localization to chromosome, telomeric region", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900701", "l": "regulation of orcinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of orcinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0015822", "l": "ornithine transport", "d": ["The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035279", "l": "miRNA-mediated gene silencing by mRNA destabilization", "d": ["An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0048679", "l": "regulation of axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902195", "l": "isovaleryl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving isovaleryl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072099", "l": "anterior/posterior pattern specification involved in ureteric bud development", "d": ["The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000140", "l": "negative regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034472", "l": "snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904537", "l": "negative regulation of mitotic telomere tethering at nuclear periphery", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042812", "l": "pheromone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0033500", "l": "carbohydrate homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002033", "l": "angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["The process that increases the diameter of a blood vessel via the renin-angiotensin system."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042321", "l": "negative regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901714", "l": "positive regulation of urea catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of urea catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018191", "l": "peptidyl-serine octanoylation", "d": ["The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903541", "l": "regulation of exosomal secretion", "d": ["Any process that modulates the frequency, rate or extent of exosomal secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0048708", "l": "astrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048338", "l": "mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900585", "l": "arugosin metabolic process", "d": ["The chemical reactions and pathways involving arugosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018148", "l": "RNA-protein covalent cross-linking via peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900383", "l": "regulation of synaptic plasticity by receptor localization to synapse", "d": ["Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0022609", "l": "multicellular organism adhesion to substrate", "d": ["The attachment of a multicellular organism to a surface or material."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007446", "l": "imaginal disc growth", "d": ["The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006679", "l": "glucosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061644", "l": "protein localization to CENP-A containing chromatin", "d": ["Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905449", "l": "regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002857", "l": "positive regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903265", "l": "positive regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072540", "l": "T-helper 17 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032680", "l": "regulation of tumor necrosis factor production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034497", "l": "protein localization to phagophore assembly site", "d": ["Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010884", "l": "positive regulation of lipid storage", "d": ["Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903673", "l": "mitotic cleavage furrow formation", "d": ["Any cleavage furrow formation that is involved in mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061239", "l": "mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090721", "l": "primary adaptive immune response involving T cells and B cells", "d": ["An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0055062", "l": "phosphate ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010913", "l": "regulation of sterigmatocystin biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905051", "l": "regulation of base-excision repair", "d": ["Any process that modulates the frequency, rate or extent of base-excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901441", "l": "poly(hydroxyalkanoate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:1901336", "l": "lactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002018", "l": "renin-angiotensin regulation of aldosterone production", "d": ["The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009758", "l": "carbohydrate utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010222", "l": "stem vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the stem of vascular plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061249", "l": "mesonephric glomerular capillary formation", "d": ["The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051342", "l": "regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046874", "l": "quinolinate metabolic process", "d": ["The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003359", "l": "noradrenergic neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035765", "l": "motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation", "d": ["The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048041", "l": "focal adhesion assembly", "d": ["The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150152", "l": "negative regulation of interleukin-17A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140202", "l": "polyamine import across plasma membrane", "d": ["The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046344", "l": "ecdysteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0014896", "l": "muscle hypertrophy", "d": ["The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905396", "l": "cellular response to flavonoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0160021", "l": "maternal-to-zygotic transition of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001241", "l": "positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051355", "l": "proprioception involved in equilibrioception", "d": ["The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048803", "l": "imaginal disc-derived male genitalia morphogenesis", "d": ["The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071492", "l": "cellular response to UV-A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042550", "l": "photosystem I stabilization", "d": ["The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014042", "l": "positive regulation of neuron maturation", "d": ["Any process that activates or increases the frequency, rate or extent of neuron maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035769", "l": "B cell chemotaxis across high endothelial venule", "d": ["The movement of a B cell to cross a high endothelial venule in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051334", "l": "meiosis I nuclear membrane reassembly", "d": ["The reformation of the nuclear membranes during meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034770", "l": "histone H4-K20 methylation", "d": ["The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904184", "l": "positive regulation of pyruvate dehydrogenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.283057202713358", "identifiers": [{"i": "GO:0010817", "l": "regulation of hormone levels", "d": ["Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0042558", "l": "pteridine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035629", "l": "N-terminal protein amino acid N-linked glycosylation", "d": ["Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071978", "l": "bacterial-type flagellum-dependent swarming motility", "d": ["Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901828", "l": "zeaxanthin bis(beta-D-glucoside) metabolic process", "d": ["The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0072003", "l": "kidney rudiment formation", "d": ["The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002464", "l": "peripheral tolerance induction to nonself antigen", "d": ["Tolerance induction to nonself antigens in the periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021889", "l": "olfactory bulb interneuron differentiation", "d": ["The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009297", "l": "pilus assembly", "d": ["The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0034094", "l": "regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904135", "l": "positive regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902941", "l": "regulation of voltage-gated chloride channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021564", "l": "vagus nerve development", "d": ["The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018340", "l": "peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine", "d": ["The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900262", "l": "regulation of DNA-directed DNA polymerase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050858", "l": "negative regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018007", "l": "N-terminal peptidyl-glycine N-glucuronylation", "d": ["The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044398", "l": "envenomation resulting in induction of edema in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070179", "l": "D-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071034", "l": "CUT catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042429", "l": "serotonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090223", "l": "chromatin-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900713", "l": "regulation of violaceol I biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021929", "l": "stellate cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045161", "l": "neuronal ion channel clustering", "d": ["The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903068", "l": "positive regulation of protein localization to cell tip", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009749", "l": "response to glucose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090335", "l": "regulation of brown fat cell differentiation", "d": ["Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902908", "l": "regulation of melanosome transport", "d": ["Any process that modulates the frequency, rate or extent of melanosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903577", "l": "cellular response to L-arginine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0042546", "l": "cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901790", "l": "3-(2,3-dihydroxyphenyl)propanoate metabolic process", "d": ["The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032734", "l": "positive regulation of interleukin-11 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900997", "l": "benzene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006846", "l": "acetate transport", "d": ["The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106096", "l": "response to ceramide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032223", "l": "negative regulation of synaptic transmission, cholinergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032099", "l": "negative regulation of appetite", "d": ["Any process that reduces appetite."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002091", "l": "negative regulation of receptor internalization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033671", "l": "negative regulation of NAD+ kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032218", "l": "riboflavin transport", "d": ["The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901065", "l": "syringal lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of syringal lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900629", "l": "methanophenazine metabolic process", "d": ["The chemical reactions and pathways involving methanophenazine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060489", "l": "planar dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates parallel to the plane of the previous bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071673", "l": "positive regulation of smooth muscle cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021759", "l": "globus pallidus development", "d": ["The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000588", "l": "positive regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0003081", "l": "regulation of systemic arterial blood pressure by renin-angiotensin", "d": ["The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007482", "l": "haltere development", "d": ["The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000710", "l": "meiotic mismatch repair", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051144", "l": "propanediol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046684", "l": "response to pyrethroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990937", "l": "xylan acetylation", "d": ["The addition of one or more acetyl groups to a xylan molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010820", "l": "positive regulation of T cell chemotaxis", "d": ["Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120042", "l": "negative regulation of macrophage proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060539", "l": "diaphragm development", "d": ["The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062176", "l": "R-loop processing", "d": ["A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000202", "l": "positive regulation of ribosomal subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007176", "l": "regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of EGF-activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0051238", "l": "sequestering of metal ion", "d": ["The process of binding or confining metal ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0051176", "l": "positive regulation of sulfur metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034181", "l": "positive regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0060259", "l": "regulation of feeding behavior", "d": ["Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0022010", "l": "central nervous system myelination", "d": ["The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120057", "l": "regulation of small intestinal transit", "d": ["Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.06015934163878", "identifiers": [{"i": "GO:0061564", "l": "axon development", "d": ["The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0034505", "l": "tooth mineralization", "d": ["The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031070", "l": "intronic snoRNA processing", "d": ["The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903300", "l": "negative regulation of hexokinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904878", "l": "negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034351", "l": "negative regulation of glial cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000521", "l": "negative regulation of immunological synapse formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099088", "l": "axonal transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014916", "l": "regulation of lung blood pressure", "d": ["The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905509", "l": "protein localization to interphase microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1904377", "l": "positive regulation of protein localization to cell periphery", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0021546", "l": "rhombomere development", "d": ["The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035778", "l": "pronephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002813", "l": "regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.149273381153577", "identifiers": [{"i": "GO:0007163", "l": "establishment or maintenance of cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901544", "l": "positive regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000245", "l": "negative regulation of FtsZ-dependent cytokinesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:1904064", "l": "positive regulation of cation transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of cation transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904369", "l": "positive regulation of sclerenchyma cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0050657", "l": "nucleic acid transport", "d": ["The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070814", "l": "hydrogen sulfide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0101024", "l": "mitotic nuclear membrane organization", "d": ["A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010247", "l": "detection of phosphate ion", "d": ["The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.703977263494721", "identifiers": [{"i": "GO:0010035", "l": "response to inorganic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045124", "l": "regulation of bone resorption", "d": ["Any process that modulates the frequency, rate or extent of bone tissue loss (resorption)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0001660", "l": "fever generation", "d": ["The heat generation process that results in a rise in body temperature above the normal, often as a response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070305", "l": "response to cGMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0010038", "l": "response to metal ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032829", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042334", "l": "taxis to electron acceptor", "d": ["The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000276", "l": "negative regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071242", "l": "cellular response to ammonium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097703", "l": "cellular response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs at the level of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010829", "l": "negative regulation of glucose transmembrane transport", "d": ["Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0010623", "l": "programmed cell death involved in cell development", "d": ["The activation of endogenous cellular processes that result in the death of a cell as part of its development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009958", "l": "positive gravitropism", "d": ["The orientation of plant parts towards gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099017", "l": "maintenance of protein localization at cell tip", "d": ["Any process in which localization of a protein is maintained at the cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0014074", "l": "response to purine-containing compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050917", "l": "sensory perception of umami taste", "d": ["The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090300", "l": "positive regulation of neural crest formation", "d": ["Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072185", "l": "metanephric cap development", "d": ["The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901181", "l": "negative regulation of cellular response to caffeine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039677", "l": "exit of virus from host cell nucleus via nuclear envelope disassembly", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0036213", "l": "contractile ring contraction", "d": ["The process of an actomyosin ring getting smaller in diameter."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097325", "l": "melanocyte proliferation", "d": ["The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009149", "l": "pyrimidine nucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043627", "l": "response to estrogen", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904071", "l": "presynaptic active zone assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0030728", "l": "ovulation", "d": ["The release of a mature ovum/oocyte from an ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044593", "l": "iron-sulfur-molybdenum cofactor assembly", "d": ["The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904060", "l": "negative regulation of locomotor rhythm", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045658", "l": "regulation of neutrophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045026", "l": "plasma membrane fusion", "d": ["The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2001244", "l": "positive regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042275", "l": "error-free postreplication DNA repair", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060621", "l": "negative regulation of cholesterol import", "d": ["Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000319", "l": "regulation of T-helper 17 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015961", "l": "diadenosine polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0043570", "l": "maintenance of DNA repeat elements", "d": ["Any process involved in sustaining the fidelity and copy number of DNA repeat elements."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905344", "l": "prostaglandin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051136", "l": "regulation of NK T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.724928399908521", "identifiers": [{"i": "GO:0030036", "l": "actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001267", "l": "regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140642", "l": "meiotic spindle formation (spindle phase two)", "d": ["The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001699", "l": "acetylcholine-induced gastric acid secretion", "d": ["The regulated release of gastric acid by parietal cells in response to acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140195", "l": "positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902087", "l": "dimethylsulfoniopropionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0080145", "l": "intracellular cysteine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of cysteine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006438", "l": "valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019456", "l": "L-cysteine catabolic process via cystine, using cysteine transaminase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046901", "l": "tetrahydrofolylpolyglutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072219", "l": "metanephric cortical collecting duct development", "d": ["The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901759", "l": "beta-L-Ara4N-lipid A metabolic process", "d": ["The chemical reactions and pathways involving beta-L-Ara4N-lipid A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902910", "l": "positive regulation of melanosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of melanosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000208", "l": "positive regulation of ribosomal small subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000425", "l": "regulation of apoptotic cell clearance", "d": ["Any process that modulates the frequency, rate or extent of apoptotic cell clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010790", "l": "meiotic sister chromatid cohesion involved in meiosis II", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019501", "l": "arsonoacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045982", "l": "negative regulation of purine nucleobase metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032474", "l": "otolith morphogenesis", "d": ["The process in which the anatomical structures of an otolith are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000399", "l": "negative regulation of thymocyte aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0055116", "l": "entry into reproductive diapause", "d": ["The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051754", "l": "meiotic sister chromatid cohesion, centromeric", "d": ["The cell cycle process in which centromeres of sister chromatids are joined during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003344", "l": "pericardium morphogenesis", "d": ["The process in which the anatomical structure of the pericardium is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009667", "l": "plastid inner membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0034312", "l": "diol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0044851", "l": "hair cycle phase", "d": ["The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036241", "l": "glutamate catabolic process to 4-hydroxybutyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097230", "l": "cell motility in response to potassium ion", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.388382942757389", "identifiers": [{"i": "GO:0007622", "l": "rhythmic behavior", "d": ["The specific behavior of an organism that recur with measured regularity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060677", "l": "ureteric bud elongation", "d": ["The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034994", "l": "microtubule organizing center attachment site organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001678", "l": "intracellular glucose homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of glucose within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904631", "l": "response to glucoside", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019076", "l": "viral release from host cell", "d": ["The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042179", "l": "nicotine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904098", "l": "regulation of protein O-linked glycosylation", "d": ["Any process that modulates the frequency, rate or extent of protein O-linked glycosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033206", "l": "meiotic cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120117", "l": "T cell meandering migration", "d": ["The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098795", "l": "global gene silencing by mRNA cleavage", "d": ["A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042665", "l": "regulation of ectodermal cell fate specification", "d": ["Any process that mediates the specification of a cell into an ectoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900563", "l": "dehydroaustinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dehydroaustinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035298", "l": "regulation of Malpighian tubule size", "d": ["Ensuring that a Malpighian tubule is the correct length and diameter."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902041", "l": "regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.587491604362903", "identifiers": [{"i": "GO:0034655", "l": "nucleobase-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060118", "l": "vestibular receptor cell development", "d": ["The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905889", "l": "positive regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0099566", "l": "regulation of postsynaptic cytosolic calcium ion concentration", "d": ["Any process that regulates the concentration of calcium in the postsynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0046902", "l": "regulation of mitochondrial membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048629", "l": "trichome patterning", "d": ["The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048543", "l": "phytochrome chromophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019539", "l": "hydroxymate-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003069", "l": "acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070175", "l": "positive regulation of enamel mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044472", "l": "envenomation resulting in modulation of calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051232", "l": "meiotic spindle elongation", "d": ["The lengthening of the distance between poles of the spindle during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902815", "l": "N,N'-diacetylchitobiose import", "d": ["The directed movement of N,N'-diacetylchitobiose into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045880", "l": "positive regulation of smoothened signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903015", "l": "regulation of exo-alpha-sialidase activity", "d": ["Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002442", "l": "serotonin secretion involved in inflammatory response", "d": ["The regulated release of serotonin by a cell as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.144425605630182", "identifiers": [{"i": "GO:0045596", "l": "negative regulation of cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034294", "l": "sexual spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043063", "l": "intercellular bridge organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046381", "l": "CMP-N-acetylneuraminate metabolic process", "d": ["The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097368", "l": "establishment of Sertoli cell barrier", "d": ["Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070268", "l": "cornification", "d": ["A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090245", "l": "axis elongation involved in somitogenesis", "d": ["The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000103", "l": "positive regulation of mammary stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031566", "l": "actomyosin contractile ring maturation", "d": ["The cellular process in which the contractile ring cytokinetic ring attains its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900511", "l": "positive regulation of pentose catabolic process to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905098", "l": "negative regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044760", "l": "modulation by symbiont of host cholinergic synaptic transmission", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034035", "l": "purine ribonucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000069", "l": "regulation of post-embryonic root development", "d": ["Any process that modulates the frequency, rate or extent of post-embryonic root development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001303", "l": "lipoxin A4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045720", "l": "negative regulation of integrin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048779", "l": "negative regulation of erythrophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903490", "l": "positive regulation of mitotic cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019379", "l": "sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)", "d": ["The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000898", "l": "regulation of glucomannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046956", "l": "positive phototaxis", "d": ["The directed movement of a cell or organism towards a source of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006579", "l": "amino-acid betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010167", "l": "response to nitrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000210", "l": "positive regulation of anoikis", "d": ["Any process that activates or increases the frequency, rate or extent of anoikis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002937", "l": "tRNA 4-thiouridine biosynthesis", "d": ["The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:2001236", "l": "regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.423950427221243", "identifiers": [{"i": "GO:0021953", "l": "central nervous system neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060654", "l": "mammary gland cord elongation", "d": ["The process in which the mammary gland sprout grows along its axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060521", "l": "mesenchymal-epithelial cell signaling involved in prostate induction", "d": ["Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031921", "l": "pyridoxal phosphate transport", "d": ["The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0006289", "l": "nucleotide-excision repair", "d": ["A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0017004", "l": "cytochrome complex assembly", "d": ["The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902017", "l": "regulation of cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061080", "l": "right horn of sinus venosus development", "d": ["The progression of the right horn of the sinus venosus from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060577", "l": "pulmonary vein morphogenesis", "d": ["The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002877", "l": "regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.182134323627913", "identifiers": [{"i": "GO:0045934", "l": "negative regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031041", "l": "O-glycan processing, core 5", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:1901661", "l": "quinone metabolic process", "d": ["The chemical reactions and pathways involving quinone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031664", "l": "regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0021578", "l": "hindbrain maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034606", "l": "response to hermaphrodite contact", "d": ["The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001249", "l": "negative regulation of ammonia assimilation cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043312", "l": "neutrophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0003010", "l": "voluntary skeletal muscle contraction", "d": ["A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039563", "l": "disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:2000968", "l": "positive regulation of cell wall polysaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904891", "l": "positive regulation of excitatory synapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032910", "l": "regulation of transforming growth factor beta3 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043165", "l": "Gram-negative-bacterium-type cell outer membrane assembly", "d": ["The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900167", "l": "negative regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090383", "l": "phagosome acidification", "d": ["Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010249", "l": "auxin conjugate metabolic process", "d": ["The chemical reactions and pathways involving auxin conjugates, a bound form of auxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015754", "l": "allose transmembrane transport", "d": ["The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072198", "l": "mesenchymal cell proliferation involved in ureter development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0002510", "l": "central B cell tolerance induction", "d": ["Tolerance induction of B cells in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007134", "l": "meiotic telophase I", "d": ["The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099151", "l": "regulation of postsynaptic density assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021873", "l": "forebrain neuroblast division", "d": ["The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902194", "l": "2-methylbut-2-enoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000370", "l": "positive regulation of clathrin-dependent endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019458", "l": "methionine catabolic process via 2-oxobutanoate", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900512", "l": "regulation of starch utilization system complex assembly", "d": ["Any process that modulates the frequency, rate or extent of starch utilization system complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016127", "l": "sterol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140909", "l": "kinetoplast DNA replication", "d": ["The process of doubling of the number of maxicircles and minicircles and distribution of the progeny into two daughter networks, which are identical to the parent kinetoplast DNA network."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0016129", "l": "phytosteroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0003057", "l": "regulation of the force of heart contraction by chemical signal", "d": ["The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905138", "l": "positive regulation of viral DNA genome packaging via site-specific sequence recognition", "d": ["Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900231", "l": "regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901839", "l": "regulation of RNA polymerase I regulatory region sequence-specific DNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099110", "l": "microtubule polymerization based protein transport to cell tip cortex", "d": ["The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045700", "l": "regulation of spermatid nuclear differentiation", "d": ["Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043579", "l": "elaioplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001129", "l": "methane biosynthetic process from dimethylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044258", "l": "intestinal lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905857", "l": "positive regulation of pentose-phosphate shunt", "d": ["Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019334", "l": "p-cymene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072129", "l": "renal capsule formation", "d": ["The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010716", "l": "negative regulation of extracellular matrix disassembly", "d": ["Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019579", "l": "aldaric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009701", "l": "isoflavonoid phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0017010", "l": "protein-phycourobilin linkage", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051785", "l": "positive regulation of nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0036075", "l": "replacement ossification", "d": ["Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903431", "l": "positive regulation of cell maturation", "d": ["Any process that activates or increases the frequency, rate or extent of cell maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035992", "l": "tendon formation", "d": ["The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042001", "l": "hermaphrodite somatic sex determination", "d": ["The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:1901874", "l": "negative regulation of post-translational protein modification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031671", "l": "primary cell septum biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032253", "l": "dense core granule localization", "d": ["Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904780", "l": "negative regulation of protein localization to centrosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:1902106", "l": "negative regulation of leukocyte differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904996", "l": "positive regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000332", "l": "regulation of blood microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of blood microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032629", "l": "interleukin-25 production", "d": ["The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000728", "l": "regulation of mRNA export from nucleus in response to heat stress", "d": ["Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071998", "l": "ascospore release from ascus", "d": ["A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901291", "l": "negative regulation of double-strand break repair via single-strand annealing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900072", "l": "positive regulation of sulfite transport", "d": ["Any process that activates or increases the frequency, rate or extent of sulfite transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035425", "l": "autocrine signaling", "d": ["Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904092", "l": "regulation of autophagic cell death", "d": ["Any process that modulates the frequency, rate or extent of autophagic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018905", "l": "dimethyl ether metabolic process", "d": ["The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090127", "l": "positive regulation of synapse maturation by synaptic transmission", "d": ["Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090507", "l": "phenylethylamine metabolic process involved in synaptic transmission", "d": ["The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904743", "l": "negative regulation of telomeric DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070952", "l": "regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061478", "l": "response to platelet aggregation inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0038010", "l": "positive regulation of signal transduction by receptor internalization", "d": ["Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002021", "l": "response to dietary excess", "d": ["The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0002514", "l": "B cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in B cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010451", "l": "floral meristem growth", "d": ["The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000122", "l": "negative regulation of stomatal complex development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903069", "l": "regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015673", "l": "silver ion transport", "d": ["The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0046632", "l": "alpha-beta T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039638", "l": "lipopolysaccharide-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000709", "l": "regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0060425", "l": "lung morphogenesis", "d": ["The process in which the anatomical structures of the lung are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0043161", "l": "proteasome-mediated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010571", "l": "positive regulation of nuclear cell cycle DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904100", "l": "positive regulation of protein O-linked glycosylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905499", "l": "trichome papilla formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a trichome papilla."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000219", "l": "positive regulation of invasive growth in response to glucose limitation", "d": ["Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0048439", "l": "flower morphogenesis", "d": ["The process in which the anatomical structures of the flower are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.095679833930788", "identifiers": [{"i": "GO:0014020", "l": "primary neural tube formation", "d": ["The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0009161", "l": "ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0001978", "l": "regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003128", "l": "heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097378", "l": "dorsal spinal cord interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036138", "l": "peptidyl-histidine hydroxylation", "d": ["The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030878", "l": "thyroid gland development", "d": ["The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900626", "l": "regulation of arugosin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of arugosin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070249", "l": "positive regulation of natural killer cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045829", "l": "negative regulation of isotype switching", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904458", "l": "regulation of substance P secretion", "d": ["Any process that modulates the frequency, rate or extent of substance P secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014712", "l": "positive regulation of branchiomeric skeletal muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052064", "l": "induction by symbiont of defense-related host reactive oxygen species production", "d": ["The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090419", "l": "negative regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0009259", "l": "ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048896", "l": "lateral line nerve glial cell migration", "d": ["The movement of a glial cell along the axons in a lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010055", "l": "atrichoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003176", "l": "aortic valve development", "d": ["The progression of the aortic valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901734", "l": "quercetin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quercetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097303", "l": "lipoprotein biosynthetic process via N-acyl transfer", "d": ["The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0019083", "l": "viral transcription", "d": ["The process by which a viral genome, or part of a viral genome, is transcribed within the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.093520287766694", "identifiers": [{"i": "GO:0044703", "l": "multi-organism reproductive process", "d": ["A biological process that directly contributes to the process of producing new individuals, involving another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0015813", "l": "L-glutamate transmembrane transport", "d": ["The directed movement of L-glutamate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071317", "l": "cellular response to isoquinoline alkaloid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0043068", "l": "positive regulation of programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034314", "l": "Arp2/3 complex-mediated actin nucleation", "d": ["The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019647", "l": "formaldehyde assimilation via ribulose monophosphate cycle", "d": ["The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0030808", "l": "regulation of nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0034764", "l": "positive regulation of transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905934", "l": "negative regulation of cell fate determination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046000", "l": "positive regulation of ecdysteroid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019523", "l": "L-idonate metabolic process", "d": ["The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035565", "l": "regulation of pronephros size", "d": ["Any process that modulates the size of a pronephric kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071163", "l": "DNA replication preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032771", "l": "regulation of tyrosinase activity", "d": ["Any process that modulates the activity of a tyrosinase enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010371", "l": "regulation of gibberellin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051569", "l": "regulation of histone H3-K4 methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046937", "l": "phytochelatin metabolic process", "d": ["The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045652", "l": "regulation of megakaryocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of megakaryocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032085", "l": "regulation of type II site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905298", "l": "regulation of intestinal epithelial cell development", "d": ["Any process that modulates the frequency, rate or extent of intestinal epithelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075302", "l": "regulation of basidiospore formation", "d": ["Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048649", "l": "caste determination, influence by genetic factors", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.231032082447712", "identifiers": [{"i": "GO:0071840", "l": "cellular component organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904969", "l": "slow muscle cell migration", "d": ["The orderly movement of a slow muscle cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071589", "l": "pyridine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021884", "l": "forebrain neuron development", "d": ["The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905890", "l": "regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0034104", "l": "negative regulation of tissue remodeling", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010932", "l": "regulation of macrophage tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of macrophage tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042741", "l": "endogenous antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015882", "l": "L-ascorbic acid transmembrane transport", "d": ["The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010512", "l": "negative regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006792", "l": "regulation of sulfur utilization", "d": ["Any process that modulates the frequency, rate or extent of sulfur utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905212", "l": "positive regulation of fibroblast chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003319", "l": "cardioblast migration to the midline involved in heart rudiment formation", "d": ["The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034474", "l": "U2 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U2 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046368", "l": "GDP-L-fucose metabolic process", "d": ["The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0080154", "l": "regulation of fertilization", "d": ["Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097104", "l": "postsynaptic membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030890", "l": "positive regulation of B cell proliferation", "d": ["Any process that activates or increases the rate or extent of B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901326", "l": "response to tetracycline", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009759", "l": "indole glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046528", "l": "imaginal disc fusion", "d": ["The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0072311", "l": "glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1900180", "l": "regulation of protein localization to nucleus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039704", "l": "viral translational shunt", "d": ["A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902136", "l": "(-)-secoisolariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060949", "l": "cardiac vascular smooth muscle cell fate commitment", "d": ["The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903670", "l": "regulation of sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061218", "l": "negative regulation of mesonephros development", "d": ["Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006432", "l": "phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002278", "l": "eosinophil activation involved in immune response", "d": ["The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0098856", "l": "intestinal lipid absorption", "d": ["Any process in which lipids are taken up from the contents of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044474", "l": "envenomation resulting in negative regulation of voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021528", "l": "commissural neuron differentiation in spinal cord", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904894", "l": "positive regulation of receptor signaling pathway via STAT", "d": ["Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042899", "l": "arabinan transmembrane transport", "d": ["The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009625", "l": "response to insect", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2001102", "l": "hexasaccharide transport", "d": ["The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032249", "l": "regulation of adenosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035079", "l": "polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007296", "l": "vitellogenesis", "d": ["The production of yolk. Yolk is a mixture of materials used for embryonic nutrition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060467", "l": "negative regulation of fertilization", "d": ["Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014905", "l": "myoblast fusion involved in skeletal muscle regeneration", "d": ["A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903610", "l": "regulation of calcium-dependent ATPase activity", "d": ["Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1990770", "l": "small intestine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0044273", "l": "sulfur compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035675", "l": "neuromast hair cell development", "d": ["The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0048737", "l": "imaginal disc-derived appendage development", "d": ["The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0032104", "l": "regulation of response to extracellular stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060414", "l": "aorta smooth muscle tissue morphogenesis", "d": ["The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. 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that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075311", "l": "positive regulation of sporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014058", "l": "negative regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990854", "l": "vacuole-ER tethering", "d": ["The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044542", "l": "plasminogen activation in another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900454", "l": "positive regulation of long-term synaptic depression", "d": ["Any process that activates or increases the frequency, rate or extent of long term synaptic depression."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098702", "l": "adenine import across plasma membrane", "d": ["The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080065", "l": "4-alpha-methyl-delta7-sterol oxidation", "d": ["A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010147", "l": "fructan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030908", "l": "protein splicing", "d": ["The post-translational removal of peptide sequences from within a protein sequence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000791", "l": "negative regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901854", "l": "5,6,7,8-tetrahydrosarcinapterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061874", "l": "positive regulation of hepatic stellate cell contraction", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034380", "l": "high-density lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002905", "l": "regulation of mature B cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901046", "l": "positive regulation of egg-laying behavior", "d": ["Any process that activates or increases the frequency, rate or extent of oviposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018190", "l": "protein octanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with octanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019800", "l": "peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan", "d": ["The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000380", "l": "alternative mRNA splicing, via spliceosome", "d": ["The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035492", "l": "negative regulation of leukotriene production involved in inflammatory response", "d": ["Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090069", "l": "regulation of ribosome biogenesis", "d": ["Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003160", "l": "endocardium morphogenesis", "d": ["The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006391", "l": "transcription initiation at mitochondrial promoter", "d": ["A transcription initiation process that takes place at a promoter on the mitochondrial chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141083", "l": "symbiont-mediated suppression of host reactive oxygen species generation", "d": ["A process in which a symbiont interferes with, inhibits or disrupts the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0035434", "l": "copper ion transmembrane transport", "d": ["The directed movement of copper cation across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060641", "l": "mammary gland duct regression in males", "d": ["The process in which the epithelium of the mammary duct is destroyed in males."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032526", "l": "response to retinoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048578", "l": "positive regulation of long-day photoperiodism, flowering", "d": ["Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905921", "l": "regulation of acetylcholine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.969489883774216", "identifiers": [{"i": "GO:0006090", "l": "pyruvate metabolic process", "d": ["The chemical reactions and pathways involving pyruvate, 2-oxopropanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.164784581475494", "identifiers": [{"i": "GO:0001822", "l": "kidney development", "d": ["The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009242", "l": "colanic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0007628", "l": "adult walking behavior", "d": ["The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905707", "l": "negative regulation of mitochondrial ATP synthesis coupled proton transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900918", "l": "negative regulation of octadecene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036069", "l": "light-dependent bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061583", "l": "colon epithelial cell chemotaxis", "d": ["The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903191", "l": "glyoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glyoxal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900489", "l": "positive regulation of [2Fe-2S] cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904647", "l": "response to rotenone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021783", "l": "preganglionic parasympathetic fiber development", "d": ["The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017194", "l": "N-terminal peptidyl-isoleucine acetylation", "d": ["The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1990942", "l": "mitotic metaphase chromosome recapture", "d": ["A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905232", "l": "cellular response to L-glutamate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000183", "l": "negative regulation of progesterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904979", "l": "negative regulation of endosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902853", "l": "negative regulation of nuclear migration during mitotic telophase", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905414", "l": "negative regulation of dense core granule exocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075307", "l": "positive regulation of conidium formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035563", "l": "positive regulation of chromatin binding", "d": ["Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060779", "l": "secondary leaflet morphogenesis", "d": ["The process in which the secondary leaflet attains its shape. 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An organic substance is a molecular entity that contains carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098915", "l": "membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072197", "l": "ureter morphogenesis", "d": ["The process in which the anatomical structures of the ureter are generated and organized. 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This function occurs over one or more cycles of nucleotide-dependent binding and release."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034332", "l": "adherens junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080156", "l": "mitochondrial mRNA modification", "d": ["The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090309", "l": "positive regulation of DNA methylation-dependent heterochromatin formation", "d": ["Any process that increases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0099624", "l": "atrial cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002799", "l": "positive regulation of antibacterial peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902321", "l": "methyl-branched fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031247", "l": "actin rod assembly", "d": ["The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097112", "l": 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905101", "l": "negative regulation of apoptosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903567", "l": "regulation of protein localization to ciliary membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051460", "l": "negative regulation of corticotropin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0016049", "l": "cell growth", "d": ["The process in which a cell irreversibly increases in size 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{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019492", "l": "proline salvage", "d": ["Any process which produces the amino acid proline from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000921", "l": "regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000448", "l": "cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061988", "l": "karyosome formation", "d": ["The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046293", "l": "formaldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032915", "l": "positive regulation of transforming growth factor beta2 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015713", "l": "phosphoglycerate transmembrane transport", "d": ["The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006421", "l": "asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099561", "l": "synaptic membrane adhesion to extracellular matrix", "d": ["The binding of a synaptic membrane to the extracellular matrix via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045970", "l": "negative regulation of juvenile hormone catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014871", "l": "cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0099587", "l": "inorganic ion import across plasma membrane", "d": ["The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032364", "l": "intracellular oxygen homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.643642695559002", "identifiers": [{"i": "GO:0022402", "l": "cell cycle process", "d": ["The cellular process that ensures successive accurate and complete genome replication and chromosome segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0034397", "l": "telomere localization", "d": ["Any process in which a telomere is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071434", "l": "cell chemotaxis to angiotensin", "d": ["The directed movement of a motile cell in response to the presence of angiotensin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0018941", "l": "organomercury metabolic process", "d": ["The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0070527", "l": "platelet aggregation", "d": ["The adhesion of one platelet to one or more other platelets via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.697875049310156", "identifiers": [{"i": "GO:0051174", "l": "regulation of phosphorus metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.745287752849443", "identifiers": [{"i": "GO:0009584", "l": "detection of visible light", "d": ["The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0051567", "l": "histone H3-K9 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901628", "l": "positive regulation of postsynaptic membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015964", "l": "diadenosine triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002568", "l": "somatic diversification of T cell receptor genes", "d": ["The somatic process that results in the generation of sequence diversity of T cell receptor genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043704", "l": "photoreceptor cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901070", "l": "guanosine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070963", "l": "positive regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0019400", "l": "alditol metabolic process", "d": ["The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046869", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide", "d": ["The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001248", "l": "regulation of ammonia assimilation cycle", "d": ["Any process that modulates the frequency, rate or extent of ammonia assimilation cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903110", "l": "regulation of single-strand break repair via homologous recombination", "d": ["Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904628", "l": "cellular response to phorbol 13-acetate 12-myristate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043589", "l": "skin morphogenesis", "d": ["The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048867", "l": "stem cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0072081", "l": "specification of nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015731", "l": "3-hydroxyphenyl propanoate transport", "d": ["The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033026", "l": "negative regulation of mast cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140711", "l": "positive regulation of Frizzled Nuclear Import pathway", "d": ["Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036205", "l": "histone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097295", "l": "morphine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904667", "l": "negative regulation of ubiquitin protein ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0000747", "l": "conjugation with cellular fusion", "d": ["A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904235", "l": "regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034152", "l": "negative regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002795", "l": "negative regulation of antimicrobial peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042453", "l": "deoxyguanosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060392", "l": "negative regulation of SMAD protein signal transduction", "d": ["Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018929", "l": "methyl fluoride metabolic process", "d": ["The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0002461", "l": "tolerance induction dependent upon immune response", "d": ["Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044847", "l": "iron acquisition from host", "d": ["The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072055", "l": "renal cortex development", "d": ["The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001300", "l": "lipoxin metabolic process", "d": ["The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000628", "l": "regulation of miRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034196", "l": "acylglycerol transport", "d": ["The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0021537", "l": "telencephalon development", "d": ["The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905411", "l": "positive regulation of mitotic cohesin unloading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0061318", "l": "renal filtration cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048549", "l": "positive regulation of pinocytosis", "d": ["Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035023", "l": "regulation of Rho protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rho protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0097152", "l": "mesenchymal cell apoptotic process", "d": ["Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031453", "l": "positive regulation of heterochromatin formation", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098735", "l": "positive regulation of the force of heart contraction", "d": ["Any process that increases the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019055", "l": "perturbation by virus of host cell cycle regulation", "d": ["Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045831", "l": "negative regulation of light-activated channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.577298431659159", "identifiers": [{"i": "GO:0032102", "l": "negative regulation of response to external stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007437", "l": "adult salivary gland morphogenesis", "d": ["The process in which the anatomical structures of the adult salivary gland are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1902577", "l": "protein localization to medial cortical node", "d": ["A process in which a protein is transported to, or maintained in, a location within a medial cortical node."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032796", "l": "uropod organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042333", "l": "chemotaxis to oxidizable substrate", "d": ["The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045623", "l": "negative regulation of T-helper cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010922", "l": "positive regulation of phosphatase activity", "d": ["Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.498969198536862", "identifiers": [{"i": "GO:0006082", "l": "organic acid metabolic process", "d": ["The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0008064", "l": "regulation of actin polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043641", "l": "novobiocin metabolic process", "d": ["The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071468", "l": "cellular response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019243", "l": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901898", "l": "negative regulation of relaxation of cardiac muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901508", "l": "positive regulation of acylglycerol transport", "d": ["Any process that activates or increases the frequency, rate or extent of acylglycerol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035920", "l": "negative regulation of high voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904714", "l": "regulation of chaperone-mediated autophagy", "d": ["Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007512", "l": "adult heart development", "d": ["The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051881", "l": "regulation of mitochondrial membrane potential", "d": ["Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019065", "l": "receptor-mediated endocytosis of virus by host cell", "d": ["Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0008089", "l": "anterograde axonal transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033086", "l": "negative regulation of extrathymic T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of 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axons away from the cell body and towards the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901365", "l": "funalenone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of funalenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071989", "l": "establishment of protein localization to spindle pole body", "d": ["The directed movement of a protein to a specific location at the spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.339867169364453", "identifiers": [{"i": "GO:0060560", "l": "developmental growth involved in morphogenesis", "d": ["The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002561", "l": "basophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019563", "l": "glycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032533", "l": "regulation of follicle cell microvillus length", "d": ["A process that modulates the length of a microvillus on a follicle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035552", "l": "oxidative single-stranded DNA demethylation", "d": ["Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905837", "l": "cellular response to triterpenoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.744761268575836", "identifiers": [{"i": "GO:1903047", "l": "mitotic cell cycle process", "d": ["A process that is part of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061881", "l": "positive regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905723", "l": "negative regulation of trypanothione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904630", "l": "cellular response to diterpene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0034085", "l": "establishment of sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0170002", "l": "halotropism", "d": ["A sodium-specific negative tropism that is crucial for surviving and thriving under high 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Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. 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A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0009119", "l": "ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071284", "l": "cellular response to lead ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046505", "l": "sulfolipid metabolic process", "d": ["The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.341211163834416", "identifiers": [{"i": "GO:0000041", "l": "transition metal ion transport", "d": ["The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0099558", "l": "maintenance of synapse structure", "d": ["A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003003", "l": "follicular fluid formation in ovarian follicle antrum involved in fused antrum stage", "d": ["The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036445", "l": "neuronal stem cell division", "d": ["The self-renewing division of a neuronal stem cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052098", "l": "formation by host of specialized structure for nutrient acquisition from symbiont", "d": ["The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018235", "l": "peptidyl-lysine carboxylation", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060051", "l": "negative regulation of protein glycosylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006244", "l": "pyrimidine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0015791", "l": "polyol transmembrane transport", "d": ["The directed movement of polyols, any polyhydric alcohol, across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014738", "l": "regulation of muscle hyperplasia", "d": ["Any process that modulates the frequency, rate or extent of muscle hyperplasia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903860", "l": "negative regulation of dendrite extension", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001779", "l": "natural killer cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045925", "l": "positive regulation of female receptivity", "d": ["Any process that activates or increases the receptiveness of a female to male advances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009911", "l": "positive regulation of flower development", "d": ["Any process that activates or increases the frequency, rate or extent of flower development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031656", "l": "positive regulation of heat dissipation", "d": ["Any process that activates or increases the rate or extent of heat dissipation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039689", "l": "negative stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061592", "l": "phosphatidylserine exposure on osteoblast involved in bone mineralization", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018243", "l": "protein O-linked glycosylation via threonine", "d": ["The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0014745", "l": "negative regulation of muscle adaptation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032348", "l": "negative regulation of aldosterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904421", "l": "response to D-galactosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044360", "l": "modulation of voltage-gated potassium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033071", "l": "vancomycin metabolic process", "d": ["The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000432", "l": "positive regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019394", "l": "glucarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032658", "l": "regulation of interleukin-15 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-15 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046638", "l": "positive regulation of alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006646", "l": "phosphatidylethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0042267", "l": "natural killer cell mediated cytotoxicity", "d": ["The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048142", "l": "germarium-derived cystoblast division", "d": ["The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042932", "l": "chrysobactin transport", "d": ["The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032884", "l": "regulation of cell wall chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006368", "l": "transcription elongation by RNA polymerase II", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060050", "l": "positive regulation of protein glycosylation", "d": ["Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140698", "l": "attachment of telomeric heterochromatin to nuclear envelope", "d": ["The process in which physical connections are formed between sub-telomeric heterochromatin and the nuclear envelope facilitating bouquet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.994177151433838", "identifiers": [{"i": "GO:0046879", "l": "hormone secretion", "d": ["The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045923", "l": "positive regulation of fatty acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.286126184974798", "identifiers": [{"i": "GO:0009605", "l": "response to external stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0006475", "l": "internal protein amino acid acetylation", "d": ["The addition of an acetyl group to a non-terminal amino acid in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0000184", "l": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900436", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to starvation", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042883", "l": "cysteine transport", "d": ["The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006675", "l": "mannosyl-inositol phosphorylceramide metabolic process", "d": ["The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0098509", "l": "sensory perception of humidity", "d": ["The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0150076", "l": "neuroinflammatory response", "d": ["The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032988", "l": "protein-RNA complex disassembly", "d": ["The disaggregation of a protein-RNA complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006367", "l": "transcription initiation at RNA polymerase II promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990054", "l": "response to temozolomide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002215", "l": "defense response to nematode", "d": ["A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002580", "l": "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003431", "l": "growth plate cartilage chondrocyte development", "d": ["The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000727", "l": "double-strand break repair via break-induced replication", "d": ["The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141010", "l": "retrotransposon silencing by RNA-directed DNA methylation", "d": ["A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904244", "l": "positive regulation of pancreatic trypsinogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000669", "l": "negative regulation of dendritic cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090042", "l": "tubulin deacetylation", "d": ["The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010264", "l": "myo-inositol hexakisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901747", "l": "prephenate(2-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prephenate(2-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905123", "l": "regulation of glucosylceramidase activity", "d": ["Any process that modulates the frequency, rate or extent of glucosylceramidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007564", "l": "regulation of chitin-based cuticle tanning", "d": ["Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0044782", "l": "cilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.458616459910786", "identifiers": [{"i": "GO:0007281", "l": "germ cell development", "d": ["The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905814", "l": "positive regulation of motor neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.973714123956164", "identifiers": [{"i": "GO:0061535", "l": "glutamate secretion, neurotransmission", "d": ["The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032210", "l": "regulation of telomere maintenance via telomerase", "d": ["Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002595", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070857", "l": "regulation of bile acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010635", "l": "regulation of mitochondrial fusion", "d": ["Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018864", "l": "acetylene metabolic process", "d": ["The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035906", "l": "descending aorta development", "d": ["The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050938", "l": "regulation of xanthophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of xanthophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902514", "l": "regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0015821", "l": "methionine transport", "d": ["The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0033366", "l": "protein localization to secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120214", "l": "negative regulation of histidine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060098", "l": "membrane reorganization involved in phagocytosis, engulfment", "d": ["The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090480", "l": "purine nucleotide-sugar transmembrane transport", "d": ["The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039545", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity", "d": ["Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032684", "l": "negative regulation of fractalkine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060963", "l": "positive regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110045", "l": "negative regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008335", "l": "female germline ring canal stabilization", "d": ["Maintenance of the structural integrity of the ring canals connecting the female germline cyst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140639", "l": "positive regulation of pyroptosis", "d": ["Any process that increases the frequency, rate or extent of pyroptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099590", "l": "neurotransmitter receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007278", "l": "pole cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902408", "l": "mitotic cytokinesis, division site positioning", "d": ["The process in which a contractile ring is positioned in a specific location during the mitotic cell cycle. This process is critical for both for both symmetric and asymmetric cell divisions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022619", "l": "generative cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019315", "l": "D-allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000215", "l": "negative regulation of proline metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001039", "l": "negative regulation of cellular response to drug", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032429", "l": "regulation of phospholipase A2 activity", "d": ["Any process that modulates the activity of the enzyme phospholipase A2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905256", "l": "negative regulation of RNA binding transcription factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044831", "l": "modulation by virus of host cytokine production", "d": ["Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0100001", "l": "regulation of skeletal muscle contraction by action potential", "d": ["Any action potential process that regulates skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901166", "l": "neural crest cell migration involved in autonomic nervous system development", "d": ["Any neural crest cell migration that is involved in autonomic nervous system development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014807", "l": "regulation of somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905403", "l": "negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071393", "l": "cellular response to progesterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019096", "l": "pole plasm mitochondrial lrRNA localization", "d": ["Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033379", "l": "maintenance of protease location in T cell secretory granule", "d": ["A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018944", "l": "tri-n-butyltin metabolic process", "d": ["The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032074", "l": "negative regulation of nuclease activity", "d": ["Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051163", "l": "D-arabitol metabolic process", "d": ["The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904585", "l": "response to putrescine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070659", "l": "inner ear sensory epithelium regeneration", "d": ["The regrowth of lost or destroyed inner ear sensory epithelia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006287", "l": "base-excision repair, gap-filling", "d": ["Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045590", "l": "negative regulation of regulatory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905178", "l": "regulation of cardiac muscle tissue regeneration", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051638", "l": "barbed-end actin filament uncapping", "d": ["The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901453", "l": "positive regulation of response to benzene", "d": ["Any process that activates or increases the frequency, rate or extent of response to benzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071340", "l": "skeletal muscle acetylcholine-gated channel clustering", "d": ["The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046551", "l": "retinal cone cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000951", "l": "methionine catabolic process to 3-methylthiopropanol", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000934", "l": "negative regulation of cellotriose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0030195", "l": "negative regulation of blood coagulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:0043467", "l": "regulation of generation of precursor metabolites and energy", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036466", "l": "synaptic vesicle recycling via endosome", "d": ["Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015779", "l": "glucuronoside transport", "d": ["The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000459", "l": "negative regulation of astrocyte chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001187", "l": "positive regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018896", "l": "dibenzothiophene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903082", "l": "positive regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901324", "l": "response to trichodermin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1903321", "l": "negative regulation of protein modification by small protein conjugation or removal", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032305", "l": "positive regulation of icosanoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034316", "l": "negative regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010245", "l": "radial microtubular system formation", "d": ["Formation of radial microtubular systems during male meiotic cytokinesis in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072288", "l": "metanephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903921", "l": "regulation of protein processing in phagocytic vesicle", "d": ["Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061969", "l": "maintenance of left sidedness", "d": ["The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900534", "l": "palmitic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of palmitic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006059", "l": "hexitol metabolic process", "d": ["The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902808", "l": "positive regulation of cell cycle G1/S phase transition", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097402", "l": "neuroblast migration", "d": ["The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140415", "l": "effector-mediated modulation of host defenses by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071398", "l": "cellular response to fatty acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0021872", "l": "forebrain generation of neurons", "d": ["The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000942", "l": "regulation of amylopectin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of amylopectin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904865", "l": "positive regulation of beta-catenin-TCF complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031024", "l": "interphase microtubule organizing center assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1903036", "l": "positive regulation of response to wounding", "d": ["Any process that activates or increases the frequency, rate or extent of response to wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035654", "l": "clathrin-coated vesicle cargo loading, AP-3-mediated", "d": ["Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0031382", "l": "mating projection formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090126", "l": "protein-containing complex assembly involved in synapse maturation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051684", "l": "maintenance of Golgi location", "d": ["Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032367", "l": "intracellular cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090557", "l": "establishment of endothelial intestinal barrier", "d": ["The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060906", "l": "negative regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070714", "l": "RNA guanosine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072254", "l": "metanephric glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098758", "l": "response to interleukin-8", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022000", "l": "forebrain induction by the anterior neural ridge", "d": ["The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002044", "l": "blood vessel endothelial cell migration involved in intussusceptive angiogenesis", "d": ["The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035094", "l": "response to nicotine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0016556", "l": "mRNA modification", "d": ["The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019050", "l": "suppression by virus of host apoptotic process", "d": ["Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0007597", "l": "blood coagulation, intrinsic pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000089", "l": "positive regulation of mesonephric glomerulus development", "d": ["Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042930", "l": "enterobactin transport", "d": ["The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0007314", "l": "oocyte anterior/posterior axis specification", "d": ["Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901416", "l": "regulation of response to ethanol", "d": ["Any process that modulates the frequency, rate or extent of response to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002649", "l": "regulation of tolerance induction to self antigen", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0008655", "l": "pyrimidine-containing compound salvage", "d": ["Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904516", "l": "myofibroblast cell apoptotic process", "d": ["Any apoptotic process in a myofibroblast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060087", "l": "relaxation of vascular associated smooth muscle", "d": ["A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "42.675209483994792", "identifiers": [{"i": "GO:0046903", "l": "secretion", "d": ["The controlled release of a substance by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.06015934163878", "identifiers": [{"i": "GO:0032870", "l": "cellular response to hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903254", "l": "hercynylselenocysteine metabolic process", "d": ["The chemical reactions and pathways involving hercynylselenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018387", "l": "N-terminal peptidyl-amino acid deamination to pyruvic acid", "d": ["The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010110", "l": "regulation of photosynthesis, dark reaction", "d": ["Any process that modulates the frequency, rate or extent of photosynthesis dark reaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0036446", "l": "myofibroblast differentiation", "d": ["The process in which an undifferentiated cell acquires the features of a myofibroblast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.681044637753267", "identifiers": [{"i": "GO:0006281", "l": "DNA repair", "d": ["The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098909", "l": "regulation of cardiac muscle cell action potential involved in regulation of contraction", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046370", "l": "fructose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009971", "l": "anastral spindle assembly involved in male meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017197", "l": "N-terminal peptidyl-proline acetylation", "d": ["The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140783", "l": "(M)-viriditoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006180", "l": "deoxyguanosine salvage", "d": ["Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036098", "l": "male germ-line stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of male germ-line stem cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0002377", "l": "immunoglobulin production", "d": ["The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017013", "l": "protein flavinylation", "d": ["The addition of a flavin group to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0002339", "l": "B cell selection", "d": ["The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0005987", "l": "sucrose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018415", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide", "d": ["The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905236", "l": "cellular response to quercetin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045067", "l": "positive extrathymic T cell selection", "d": ["The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034375", "l": "high-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0002028", "l": "regulation of sodium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070810", "l": "positive regulation of Hulle cell development", "d": ["Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071640", "l": "regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048635", "l": "negative regulation of muscle organ development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900740", "l": "positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051237", "l": "maintenance of RNA location", "d": ["Any process in which RNA is maintained in a location and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046345", "l": "abscisic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035017", "l": "cuticle pattern formation", "d": ["The regionalization process that gives rise to the patterns of cell differentiation in the cuticle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000167", "l": "regulation of planar cell polarity pathway involved in neural tube closure", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904402", "l": "response to nocodazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0007416", "l": "synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072192", "l": "ureter epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070109", "l": "positive regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:2000816", "l": "negative regulation of mitotic sister chromatid separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042119", "l": "neutrophil activation", "d": ["The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110099", "l": "negative regulation of calcium import into the mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006571", "l": "tyrosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905457", "l": "negative regulation of lymphoid progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032965", "l": "regulation of collagen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051890", "l": "regulation of cardioblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048236", "l": "plant-type sporogenesis", "d": ["The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031107", "l": "septin ring disassembly", "d": ["The controlled breakdown of a septin ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902396", "l": "protein localization to bicellular tight junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042701", "l": "progesterone secretion", "d": ["The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1901532", "l": "regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051882", "l": "mitochondrial depolarization", "d": ["The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043694", "l": "monoterpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0033032", "l": "regulation of myeloid cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070104", "l": "negative regulation of interleukin-6-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032692", "l": "negative regulation of interleukin-1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990146", "l": "protein localization to rhabdomere", "d": ["A process in which a protein is transported to, or maintained in, a location within a rhabdomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000731", "l": "negative regulation of termination of RNA polymerase I transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010422", "l": "regulation of brassinosteroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010037", "l": "response to carbon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070606", "l": "regulation of (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010424", "l": "DNA methylation on cytosine within a CG sequence", "d": ["The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006430", "l": "lysyl-tRNA aminoacylation", "d": ["The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. 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The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903283", "l": "negative regulation of glutathione peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061985", "l": "carbon catabolite repression", "d": ["A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046092", "l": "deoxycytidine metabolic process", "d": ["The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031630", "l": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051571", "l": "positive regulation of histone H3-K4 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097310", "l": "cap2 mRNA methylation", "d": ["Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042984", "l": "regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018266", "l": "GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002261", "l": "mucosal lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019343", "l": "cysteine biosynthetic process via cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905585", "l": "regulation of outer hair cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099050", "l": "vesicle scission", "d": ["The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. 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The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051004", "l": "regulation of lipoprotein lipase activity", "d": ["Any process that modulates the activity of the enzyme lipoprotein lipase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061123", "l": "negative regulation of positive chemotaxis to cAMP", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900432", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.03673969480753", "identifiers": [{"i": "GO:0042180", "l": "cellular ketone metabolic process", "d": ["The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904612", "l": "response to 2,3,7,8-tetrachlorodibenzodioxine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900625", "l": "positive regulation of monocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901795", "l": "3-(3-hydroxyphenyl)propanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901766", "l": "phosphinothricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphinothricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150089", "l": "multiple spine synapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902343", "l": "regulation of maltose transport", "d": ["Any process that modulates the frequency, rate or extent of maltose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901200", "l": "negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress", "d": ["Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046208", "l": "spermine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0110029", "l": "negative regulation of meiosis I", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015940", "l": "pantothenate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. 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The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003142", "l": "cardiogenic plate morphogenesis", "d": ["The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0030537", "l": "larval behavior", "d": ["Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0003143", "l": "embryonic heart tube morphogenesis", "d": ["The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009945", "l": "radial axis specification", "d": ["The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018291", "l": "molybdenum incorporation into iron-sulfur cluster", "d": ["The incorporation of molybdenum into an iron-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009439", "l": "cyanate metabolic process", "d": ["The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071929", "l": "alpha-tubulin acetylation", "d": ["The addition of an acetyl group to the lysine 40 residue of alpha-tubulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099039", "l": "sphingolipid translocation", "d": ["The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019545", "l": "arginine catabolic process to succinate", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0008299", "l": "isoprenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904148", "l": "cellular response to nonylphenol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904859", "l": "positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051126", "l": "negative regulation of actin nucleation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903513", "l": "endoplasmic reticulum to cytosol transport", "d": ["The directed movement of substances from endoplasmic reticulum to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0016078", "l": "tRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0048634", "l": "regulation of muscle organ development", "d": ["Any process that modulates the frequency, rate or extent of muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902621", "l": "actomyosin contractile ring disassembly", "d": ["The disaggregation of an actomyosin contractile ring into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070689", "l": "L-threonine catabolic process to propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000386", "l": "positive regulation of ovarian follicle development", "d": ["Any process that activates or increases the frequency, rate or extent of ovarian follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0070663", "l": "regulation of leukocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003202", "l": "endocardial cushion to mesenchymal transition involved in cardiac skeleton development", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061553", "l": "ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900831", "l": "D-leucine metabolic process", "d": ["The chemical reactions and pathways involving D-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046944", "l": "protein carbamoylation", "d": ["The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018400", "l": "peptidyl-proline hydroxylation to 3-hydroxy-L-proline", "d": ["The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042205", "l": "chlorinated hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019070", "l": "viral genome maturation", "d": ["The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060044", "l": "negative regulation of cardiac muscle cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043951", "l": "negative regulation of cAMP-mediated signaling", "d": ["Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903823", "l": "telomere single strand break repair", "d": ["Single strand break repair that takes place in a telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002934", "l": "desmosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0042545", "l": "cell wall modification", "d": ["The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140710", "l": "regulation of Frizzled Nuclear Import pathway", "d": ["Any process that modulates the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018279", "l": "protein N-linked glycosylation via asparagine", "d": ["The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070710", "l": "RNA uridine deletion", "d": ["The modification of an RNA molecule by removal of a uridine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000194", "l": "regulation of female gonad development", "d": ["Any process that modulates the frequency, rate or extent of female gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140074", "l": "cardiac endothelial to mesenchymal transition", "d": ["A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042863", "l": "pyochelin metabolic process", "d": ["The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062100", "l": "positive regulation of programmed necrotic cell death", "d": ["Any process that increases the frequency, rate or extent of programmed necrotic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019434", "l": "sophorosyloxydocosanoate metabolic process", "d": ["The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905887", "l": "autoinducer AI-2 transmembrane transport", "d": ["The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021793", "l": "chemorepulsion of branchiomotor axon", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0045089", "l": "positive regulation of innate immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097150", "l": "neuronal stem cell population maintenance", "d": ["Any process in by an organism or tissue maintains a population of neuronal stem cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007388", "l": "posterior compartment specification", "d": ["The process involved in the specification of cell identity in the posterior compartments of the segmented embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033119", "l": "negative regulation of RNA splicing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0009063", "l": "amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902362", "l": "melanocyte apoptotic process", "d": ["Any apoptotic process in a melanocyte, the main structural component of the epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035820", "l": "negative regulation of renal sodium excretion by angiotensin", "d": ["The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000093", "l": "mitotic telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0031048", "l": "regulatory ncRNA-mediated heterochromatin formation", "d": ["A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097738", "l": "substrate mycelium formation", "d": ["The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052422", "l": "modulation by host of symbiont catalytic activity", "d": ["The process in which a host organism effects a change in the enzyme activity of its symbiont organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010191", "l": "mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075253", "l": "positive regulation of uredospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036526", "l": "peptidyl-cysteine deglycation", "d": ["The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.426889726972838", "identifiers": [{"i": "GO:0006631", "l": "fatty acid metabolic process", "d": ["The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000456", "l": "negative regulation of T-helper 17 cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048465", "l": "corolla development", "d": ["The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0030178", "l": "negative regulation of Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905459", "l": "regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010778", "l": "meiotic DNA repair synthesis involved in reciprocal meiotic recombination", "d": ["The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035143", "l": "caudal fin morphogenesis", "d": ["The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048135", "l": "female germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single female gonial founder cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900821", "l": "orlandin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of orlandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900048", "l": "positive regulation of hemostasis", "d": ["Any process that activates or increases the frequency, rate or extent of hemostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120049", "l": "snRNA (adenine-N6)-methylation", "d": ["The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0047496", "l": "vesicle transport along microtubule", "d": ["The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072199", "l": "regulation of mesenchymal cell proliferation involved in ureter development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900386", "l": "positive regulation of flavonol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0075001", "l": "adhesion of symbiont infection structure to host", "d": ["The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0099171", "l": "presynaptic modulation of chemical synaptic transmission", "d": ["Any process, acting in the presynapse that results in modulation of chemical synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021657", "l": "rhombomere 2 formation", "d": ["The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900684", "l": "negative regulation of fumonisin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070462", "l": "plus-end specific microtubule depolymerization", "d": ["The removal of tubulin heterodimers from the plus end of a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905404", "l": "positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000633", "l": "positive regulation of pre-miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of pre-microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002588", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110136", "l": "protein-RNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032694", "l": "negative regulation of interleukin-11 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075133", "l": "perturbation of host calcium or calmodulin-mediated signal transduction", "d": ["A process in which a symbiont alters or subverts a calcium or calmodulin-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048715", "l": "negative regulation of oligodendrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0048707", "l": "instar larval or pupal morphogenesis", "d": ["The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905670", "l": "TORC2 complex disassembly", "d": ["The disaggregation of a TORC2 complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048458", "l": "floral whorl formation", "d": ["The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071769", "l": "mycolate cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070129", "l": "regulation of mitochondrial translation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072071", "l": "kidney interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.233007914380636", "identifiers": [{"i": "GO:0019219", "l": "regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904588", "l": "cellular response to glycoprotein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904463", "l": "ergosteryl 3-beta-D-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902154", "l": "positive regulation of response to DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021715", "l": "inferior olivary nucleus formation", "d": ["The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035007", "l": "regulation of melanization defense response", "d": ["Any process that affects the rate, extent or location of the melanization defense response during injury or invasion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070151", "l": "mitochondrial histidyl-tRNA aminoacylation", "d": ["The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046687", "l": "response to chromate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902810", "l": "negative regulation of skeletal muscle fiber differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035010", "l": "encapsulation of foreign target", "d": ["Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007146", "l": "meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.423950427221243", "identifiers": [{"i": "GO:0075136", "l": "response to host", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006999", "l": "nuclear pore organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002713", "l": "negative regulation of B cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072308", "l": "negative regulation of metanephric nephron tubule epithelial cell differentiation", "d": ["Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.608741564042447", "identifiers": [{"i": "GO:0009566", "l": "fertilization", "d": ["The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071488", "l": "cellular response to very low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010774", "l": "meiotic strand invasion involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901422", "l": "response to butan-1-ol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015897", "l": "organomercurial transport", "d": ["The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007390", "l": "germ-band shortening", "d": ["The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0035178", "l": "turning behavior", "d": ["Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032084", "l": "regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901145", "l": "mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072255", "l": "metanephric glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044131", "l": "negative regulation of development of symbiont in host", "d": ["Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.724928399908521", "identifiers": [{"i": "GO:0031349", "l": "positive regulation of defense response", "d": ["Any process that activates or increases the frequency, rate or extent of a defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072360", "l": "vascular cord development", "d": ["The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900791", "l": "shamixanthone metabolic process", "d": ["The chemical reactions and pathways involving shamixanthone."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0048709", "l": "oligodendrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990697", "l": "protein depalmitoleylation", "d": ["The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010999", "l": "regulation of eIF2 alpha phosphorylation by heme", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1904888", "l": "cranial skeletal system development", "d": ["The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0090023", "l": "positive regulation of neutrophil chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032118", "l": "horsetail-astral microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035210", "l": "prepupal development", "d": ["The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046501", "l": "protoporphyrinogen IX metabolic process", "d": ["The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900139", "l": "negative regulation of arachidonic acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032272", "l": "negative regulation of protein polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905533", "l": "negative regulation of leucine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034983", "l": "peptidyl-lysine deacetylation", "d": ["The removal of an acetyl group from an acetylated lysine residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.681044637753267", "identifiers": [{"i": "GO:0006310", "l": "DNA recombination", "d": ["Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046754", "l": "viral exocytosis", "d": ["The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1902369", "l": "negative regulation of RNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006033", "l": "chitin localization", "d": ["A process in which chitin is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046799", "l": "recruitment of helicase-primase complex to DNA lesions", "d": ["The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072056", "l": "pyramid development", "d": ["The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007543", "l": "sex determination, somatic-gonadal interaction", "d": ["The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042670", "l": "retinal cone cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001982", "l": "baroreceptor response to decreased systemic arterial blood pressure", "d": ["The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060462", "l": "lung lobe development", "d": ["The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901634", "l": "positive regulation of synaptic vesicle membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090604", "l": "surface biofilm formation", "d": ["A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034143", "l": "regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021569", "l": "rhombomere 3 development", "d": ["The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009765", "l": "photosynthesis, light harvesting", "d": ["Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900162", "l": "negative regulation of phospholipid scramblase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070910", "l": "cell wall macromolecule catabolic process involved in cell wall disassembly", "d": ["The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900974", "l": "regulation of tatiopterin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048847", "l": "adenohypophysis formation", "d": ["The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900729", "l": "regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001766", "l": "membrane raft polarization", "d": ["The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900721", "l": "positive regulation of uterine smooth muscle relaxation", "d": ["Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001019", "l": "positive regulation of retrograde axon cargo transport", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034346", "l": "positive regulation of type III interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901965", "l": "endoplasmic reticulum to chloroplast transport", "d": ["The directed movement of substances from endoplasmic reticulum to chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1901662", "l": "quinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinone."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051875", "l": "pigment granule localization", "d": ["Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904327", "l": "protein localization to cytosolic proteasome complex", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0022001", "l": "negative regulation of anterior neural cell fate commitment of the neural plate", "d": ["Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140425", "l": "galactose import across plasma membrane", "d": ["The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990646", "l": "cellular response to prolactin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032076", "l": "negative regulation of deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045987", "l": "positive regulation of smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061952", "l": "midbody abscission", "d": ["The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902206", "l": "negative regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009115", "l": "xanthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903042", "l": "negative regulation of chondrocyte hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000673", "l": "positive regulation of motor neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044835", "l": "hydrogen generation via nitrogenase", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044696", "l": "killing by virus of host cell by post-segregational killing", "d": ["The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045138", "l": "nematode male tail tip morphogenesis", "d": ["The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901245", "l": "positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization", "d": ["The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051014", "l": "actin filament severing", "d": ["The process in which an actin filament is broken down into smaller filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071866", "l": "negative regulation of apoptotic process in bone marrow cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902499", "l": "positive regulation of protein autoubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein autoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061300", "l": "cerebellum vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035264", "l": "multicellular organism growth", "d": ["The increase in size or mass of an entire multicellular organism, as opposed to cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044622", "l": "negative regulation of cell migration in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043372", "l": "positive regulation of CD4-positive, alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0042693", "l": "muscle cell fate commitment", "d": ["The process in which the cellular identity of muscle cells is acquired and determined."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002477", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031998", "l": "regulation of fatty acid beta-oxidation", "d": ["Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072270", "l": "metanephric short nephron development", "d": ["The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0051101", "l": "regulation of DNA binding", "d": ["Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990416", "l": "cellular response to brain-derived neurotrophic factor stimulus", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046847", "l": "filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902072", "l": "negative regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072277", "l": "metanephric glomerular capillary formation", "d": ["The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070837", "l": "dehydroascorbic acid transport", "d": ["The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140991", "l": "piRNA-mediated gene silencing by mRNA destabilization", "d": ["A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0008637", "l": "apoptotic mitochondrial changes", "d": ["The morphological and physiological alterations undergone by mitochondria during apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044179", "l": "hemolysis in another organism", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903602", "l": "thermospermine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thermospermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003383", "l": "apical constriction", "d": ["The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010762", "l": "regulation of fibroblast migration", "d": ["Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046535", "l": "detection of chemical stimulus involved in sensory perception of umami taste", "d": ["The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046618", "l": "xenobiotic export from cell", "d": ["The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071297", "l": "cellular response to cobalamin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008258", "l": "head involution", "d": ["Movement of the anterior ectoderm to the interior of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002529", "l": "regulation of plasma kallikrein-kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002416", "l": "IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "d": ["The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106385", "l": "dIMP salvage", "d": ["Any process which produces a dIMP from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006499", "l": "N-terminal protein myristoylation", "d": ["The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905774", "l": "regulation of DNA helicase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.004580193011144", "identifiers": [{"i": "GO:0006974", "l": "DNA damage response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097681", "l": "double-strand break repair via alternative nonhomologous end joining", "d": ["An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048295", "l": "positive regulation of isotype switching to IgE isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051459", "l": "regulation of corticotropin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015680", "l": "protein maturation by copper ion transfer", "d": ["A process that contributes to the delivery of copper ions to a target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0045806", "l": "negative regulation of endocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062034", "l": "L-pipecolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060407", "l": "negative regulation of penile erection", "d": ["Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160071", "l": "prevention of polyspermy during double fertilization", "d": ["The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010418", "l": "rhamnogalacturonan II backbone metabolic process", "d": ["The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900015", "l": "regulation of cytokine production involved in inflammatory response", "d": ["Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032479", "l": "regulation of type I interferon production", "d": ["Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032469", "l": "endoplasmic reticulum calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018974", "l": "2,4,6-trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061131", "l": "pancreas field specification", "d": ["The process in which a specific region of the gut is delineated into the area in which the pancreas will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0016311", "l": "dephosphorylation", "d": ["The process of removing one or more phosphoric (ester or anhydride) residues from a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0097176", "l": "epoxide metabolic process", "d": ["The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060221", "l": "retinal rod cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905635", "l": "FACT complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a FACT complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098756", "l": "response to interleukin-21", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0007088", "l": "regulation of mitotic nuclear division", "d": ["Any process that modulates the frequency, rate or extent of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0060602", "l": "branch elongation of an epithelium", "d": ["The growth process in which a branch increases in length from its base to its tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015741", "l": "fumarate transport", "d": ["The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045938", "l": "positive regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030034", "l": "microvillar actin bundle assembly", "d": ["Assembly of the parallel bundle of actin filaments at the core of a microvillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900800", "l": "cspyrone B1 metabolic process", "d": ["The chemical reactions and pathways involving cspyrone B1."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0035051", "l": "cardiocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046952", "l": "ketone body catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035684", "l": "helper T cell extravasation", "d": ["The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044363", "l": "modulation of potassium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0072523", "l": "purine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904695", "l": "positive regulation of vascular associated smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:2000832", "l": "negative regulation of steroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904106", "l": "protein localization to microvillus", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048671", "l": "negative regulation of collateral sprouting", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0000909", "l": "sporocarp development involved in sexual reproduction", "d": ["The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045755", "l": "negative regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990502", "l": "dense core granule maturation", "d": ["Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002413", "l": "tolerance induction to tumor cell", "d": ["A process of tolerance induction which leads to immunological tolerance of a tumor."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044576", "l": "pentose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0003097", "l": "renal water transport", "d": ["The directed movement of water (H2O) by the renal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000881", "l": "regulation of starch catabolic process", "d": ["Any process that modulates the frequency, rate or extent of starch catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106410", "l": "box C/D RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of a box C/D RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.240550988190179", "identifiers": [{"i": "GO:0001841", "l": "neural tube formation", "d": ["The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.423950427221243", "identifiers": [{"i": "GO:0061337", "l": "cardiac conduction", "d": ["Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140763", "l": "programmed DNA elimination by elimination of internal DNA segments", "d": ["A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.292849836240194", "identifiers": [{"i": "GO:0048584", "l": "positive regulation of response to stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060134", "l": "prepulse inhibition", "d": ["The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0002643", "l": "regulation of tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904706", "l": "negative regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000427", "l": "positive regulation of apoptotic cell clearance", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903456", "l": "positive regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019670", "l": "anaerobic glutamate catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150111", "l": "regulation of transepithelial transport", "d": ["Any process that modulates the frequency, rate or extent of transepithelial transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0060249", "l": "anatomical structure homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0030449", "l": "regulation of complement activation", "d": ["Any process that modulates the frequency, rate or extent of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002745", "l": "antigen processing and presentation initiated by receptor mediated uptake of antigen", "d": ["Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048655", "l": "anther wall tapetum morphogenesis", "d": ["The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003098", "l": "tubuloglomerular feedback", "d": ["The process in which blood volume is regulated due to a change in the rate of glomerular filtration. 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formation in or on host organism", "d": ["The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904410", "l": "negative regulation of secretory granule organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062171", "l": "lutein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lutein."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.149273381153577", "identifiers": [{"i": "GO:0048736", "l": "appendage development", "d": ["The process whose specific outcome is the progression of an appendage over 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An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901074", "l": "regulation of engulfment of apoptotic cell", "d": ["Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0007635", "l": "chemosensory behavior", "d": ["Behavior that is dependent upon the sensation of chemicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905920", "l": "positive regulation of CoA-transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CoA-transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046356", "l": "acetyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018313", "l": "peptide cross-linking via L-alanyl-5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000677", "l": "regulation of transcription regulatory region DNA binding", "d": ["Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0002119", "l": "nematode larval development", "d": ["The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019279", "l": "L-methionine biosynthetic process from L-homoserine via cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000229", "l": "regulation of pancreatic stellate cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900240", "l": "negative regulation of phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010588", "l": "cotyledon vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071587", "l": "CAAX-box protein modification", "d": ["The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039004", "l": "specification of pronephric proximal tubule identity", "d": ["The process in which the proximal tubule of the pronephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0009313", "l": "oligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901034", "l": "regulation of L-glutamine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-glutamine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904300", "l": "positive regulation of transcytosis", "d": ["Any process that activates or increases the frequency, rate or extent of transcytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0098764", "l": "meiosis I cell cycle phase", "d": ["A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900233", "l": "positive regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032470", "l": "positive regulation of endoplasmic reticulum calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.752087540765736", "identifiers": [{"i": "GO:0051052", "l": "regulation of DNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0099024", "l": "plasma membrane invagination", "d": ["An infolding of the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075035", "l": "appressorium maturation", "d": ["The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075292", "l": "negative regulation of aplanospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902423", "l": "regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010085", "l": "polarity specification of proximal/distal axis", "d": ["Any process resulting in the establishment of polarity along the proximal/distal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048490", "l": "anterograde synaptic vesicle transport", "d": ["The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902832", "l": "negative regulation of cell proliferation in dorsal spinal cord", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001139", "l": "negative regulation of phospholipid transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902049", "l": "neosartoricin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neosartoricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0050914", "l": "sensory perception of salty taste", "d": ["The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090671", "l": "telomerase RNA localization to Cajal body", "d": ["A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018952", "l": "parathion metabolic process", "d": ["The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904807", "l": "negative regulation of protein oxidation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042258", "l": "molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide", "d": ["The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046063", "l": "dCMP metabolic process", "d": ["The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046115", "l": "guanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090460", "l": "intracellular threonine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of threonine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003331", "l": "positive regulation of extracellular matrix constituent secretion", "d": ["Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021711", "l": "cerebellar unipolar brush cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019916", "l": "peptidyl-D-alanine racemization, direct", "d": ["The racemization of peptidyl-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045609", "l": "positive regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016024", "l": "CDP-diacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904641", "l": "response to dinitrophenol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038032", "l": "termination of G protein-coupled receptor signaling pathway", "d": ["The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061938", "l": "protein localization to somatodendritic compartment", "d": ["A process in which a protein is transported to or maintained in a location within the somatodendritic compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051664", "l": "nuclear pore localization", "d": ["Any process in which nuclear pores are transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090220", "l": "chromosome localization to nuclear envelope involved in homologous chromosome segregation", "d": ["The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055026", "l": "negative regulation of cardiac muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006231", "l": "dTMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901686", "l": "glutathione derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutathione derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070708", "l": "RNA cytidine insertion", "d": ["The modification of an RNA molecule by insertion of a cytidine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090453", "l": "aspartate transmembrane import into vacuole", "d": ["The directed movement of aspartate into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000492", "l": "regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0050908", "l": "detection of light stimulus involved in visual perception", "d": ["The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032747", "l": "positive regulation of interleukin-23 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-23 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.078122804282714", "identifiers": [{"i": "GO:0061458", "l": "reproductive system development", "d": ["The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035498", "l": "carnosine metabolic process", "d": ["The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034121", "l": "regulation of toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015957", "l": "bis(5'-nucleosidyl) oligophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048290", "l": "isotype switching to IgA isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903452", "l": "positive regulation of G1 to G0 transition", "d": ["Any process that activates or increases the frequency, rate or extent of G1 to G0 transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048797", "l": "swim bladder formation", "d": ["The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097403", "l": "cellular response to raffinose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0045911", "l": "positive regulation of DNA recombination", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.724928399908521", "identifiers": [{"i": "GO:0006820", "l": "monoatomic anion transport", "d": ["The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097021", "l": "lymphocyte migration into lymphoid organs", "d": ["The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0090713", "l": "immunological memory process", "d": ["Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019375", "l": "galactolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050845", "l": "teichuronic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902269", "l": "positive regulation of polyamine transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018125", "l": "peptidyl-cysteine methylation", "d": ["The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036059", "l": "nephrocyte diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035807", "l": "induction of blood coagulation in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.341211163834416", "identifiers": [{"i": "GO:0006473", "l": "protein acetylation", "d": ["The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035431", "l": "negative regulation of gluconate transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0003009", "l": "skeletal muscle contraction", "d": ["A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098906", "l": "regulation of Purkinje myocyte action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. 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Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900914", "l": "regulation of octadecene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of octadecene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000967", "l": "rRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090531", "l": "L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072236", "l": "metanephric loop of Henle development", "d": ["The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034304", "l": "actinomycete-type spore formation", "d": ["The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.753431535235705", "identifiers": [{"i": "GO:0055088", "l": "lipid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of lipid within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990051", "l": "activation of protein kinase C activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase C."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002190", "l": "cap-independent translational initiation", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009751", "l": "response to salicylic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904632", "l": "cellular response to glucoside", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0010232", "l": "vascular transport", "d": ["The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003429", "l": "growth plate cartilage chondrocyte morphogenesis", "d": ["The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034371", "l": "chylomicron remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0010566", "l": "regulation of ketone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0031163", "l": "metallo-sulfur cluster assembly", "d": ["The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097096", "l": "facial suture morphogenesis", "d": ["The process in which any suture between facial bones is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002031", "l": "G protein-coupled receptor internalization", "d": ["The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042860", "l": "achromobactin metabolic process", "d": ["The chemical reactions and pathways involving achromobactin, a citrate siderophore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990010", "l": "compound eye retinal cell apoptotic process", "d": ["Any apoptotic process in a compound eye retinal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044256", "l": "protein digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0055122", "l": "response to very low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006173", "l": "dADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0080009", "l": "mRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045451", "l": "pole plasm oskar mRNA localization", "d": ["Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0043476", "l": "pigment accumulation", "d": ["The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000092", "l": "positive regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044629", "l": "negative regulation of complement activation, classical pathway in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0002889", "l": "regulation of immunoglobulin mediated immune response", "d": ["Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014740", "l": "negative regulation of muscle hyperplasia", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.999711975764193", "identifiers": [{"i": "GO:0051093", "l": "negative regulation of developmental process", "d": ["Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002602", "l": "negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0097502", "l": "mannosylation", "d": ["The covalent attachment of a mannose residue to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010893", "l": "positive regulation of steroid biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035507", "l": "regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of 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"GO:0042159", "l": "lipoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048391", "l": "intermediate mesoderm formation", "d": ["The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098997", "l": "fusion of virus membrane with host outer membrane", "d": ["Fusion of a viral membrane with the host cell outer membrane during viral entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0006480", "l": "N-terminal protein amino acid methylation", "d": ["The methylation of the N-terminal amino acid of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071321", "l": "cellular response to cGMP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.295391821436155", "identifiers": [{"i": "GO:0007601", "l": "visual perception", "d": ["The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0022605", "l": "mammalian oogenesis stage", "d": ["A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0051347", "l": "positive regulation of transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030917", "l": "midbrain-hindbrain boundary development", "d": ["The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006189", "l": "'de novo' IMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905094", "l": "regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.035460556535", "identifiers": [{"i": "GO:0051668", "l": "localization within membrane", "d": ["Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035921", "l": "desmosome disassembly", "d": ["The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032017", "l": "positive regulation of Ran protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000429", "l": "negative regulation of neutrophil aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140193", "l": "regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904844", "l": "response to L-glutamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902656", "l": "calcium ion import into cytosol", "d": ["The directed movement of calcium ion into a cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046469", "l": "platelet activating factor metabolic process", "d": ["The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021619", "l": "hypoglossal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900522", "l": "negative regulation of response to amylopectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905746", "l": "positive regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0044772", "l": "mitotic cell cycle phase transition", "d": ["The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006147", "l": "guanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072299", "l": "negative regulation of metanephric glomerulus development", "d": ["Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061071", "l": "urethra epithelium development", "d": ["The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015773", "l": "raffinose transport", "d": ["The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060274", "l": "maintenance of stationary phase", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0006450", "l": "regulation of translational fidelity", "d": ["Any process that modulates the ability of the translational apparatus to interpret the genetic code."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071809", "l": "regulation of fever generation by regulation of prostaglandin biosynthesis", "d": ["Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000217", "l": "regulation of invasive growth in response to glucose limitation", "d": ["Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072038", "l": "mesenchymal stem cell maintenance involved in nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000166", "l": "negative regulation of planar cell polarity pathway involved in pericardium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010511", "l": "regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006537", "l": "glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051756", "l": "meiotic sister chromatid centromere separation", "d": ["The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016144", "l": "S-glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030704", "l": "vitelline membrane formation", "d": ["Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021959", "l": "cuneatus tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060730", "l": "regulation of intestinal epithelial structure maintenance", "d": ["Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042697", "l": "menopause", "d": ["Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0050805", "l": "negative regulation of synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048742", "l": "regulation of skeletal muscle fiber development", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0021988", "l": "olfactory lobe development", "d": ["The progression of the olfactory lobe over time from its initial formation until its mature state. 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An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071328", "l": "cellular response to maltose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1902882", "l": "regulation of response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902092", "l": "positive regulation of fumagillin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050788", "l": "sequestering of mercury", "d": ["The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030511", "l": "positive regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048392", "l": "intermediate mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043405", "l": "regulation of MAP kinase activity", "d": ["Any process that modulates the frequency, rate or extent of MAP kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060843", "l": "venous endothelial cell differentiation", "d": ["The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070458", "l": "cellular detoxification of nitrogen compound", "d": ["Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. 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In some cases this can cause malfunctioning of the cells and death of the target organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019473", "l": "L-lysine catabolic process to glutarate, by acetylation", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:0031099", "l": "regeneration", "d": ["The regrowth of a lost or destroyed body part, such as an organ or tissue. 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The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003036", "l": "detection of pH by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0097384", "l": "cellular lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071411", "l": "cellular response to fluoxetine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010118", "l": "stomatal movement", "d": ["The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042397", "l": "phosphagen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060008", "l": "Sertoli cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060610", "l": "mesenchymal cell differentiation involved in mammary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060594", "l": "mammary gland specification", "d": ["The regionalization process in which the mammary line is specified. 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It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106273", "l": "cytosol to ERGIC protein transport", "d": ["The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905828", "l": "regulation of prostaglandin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of prostaglandin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015956", "l": "bis(5'-nucleosidyl) oligophosphate metabolic process", "d": ["The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901768", "l": "carbapenem catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbapenem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036248", "l": "phytochelatin 4 import into vacuole", "d": ["The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050930", "l": "induction of positive chemotaxis", "d": ["Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018425", "l": "O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106305", "l": "mannogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010924", "l": "regulation of inositol-polyphosphate 5-phosphatase activity", "d": ["Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071970", "l": "fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0002687", "l": "positive regulation of leukocyte migration", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903361", "l": "protein localization to basolateral plasma membrane", "d": ["Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0090559", "l": "regulation of membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900618", "l": "regulation of shoot system morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of shoot morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032310", "l": "prostaglandin secretion", "d": ["The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0051709", "l": "regulation of killing of cells of another organism", "d": ["Any process that modulates the frequency, rate or extent of the killing by an organism of cells in 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as a result of a chondroitin 6'-sulfate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051543", "l": "regulation of elastin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902240", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0010212", "l": "response to ionizing radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, 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Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. 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See also glyoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.858950277264299", "identifiers": [{"i": "GO:0009165", "l": "nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034119", "l": "negative regulation of erythrocyte aggregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090345", "l": "cellular organohalogen metabolic process", "d": ["The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070849", "l": "response to epidermal growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014844", "l": "myoblast proliferation involved in skeletal muscle regeneration", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. 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A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0001910", "l": "regulation of leukocyte mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016598", "l": "protein arginylation", "d": ["The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031440", "l": "regulation of mRNA 3'-end processing", "d": ["Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031285", "l": "regulation of sorocarp stalk cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000637", "l": "positive regulation of miRNA-mediated gene silencing", "d": ["A process that activates or increases the frequency, rate or extent of gene silencing by a microRNA (miRNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0044785", "l": "metaphase/anaphase transition of meiotic cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0034309", "l": "primary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019406", "l": "hexitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061882", "l": "negative regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042341", "l": "cyanogenic glycoside metabolic process", "d": ["The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000065", "l": "negative regulation of cortisol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010609", "l": "mRNA localization resulting in post-transcriptional regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0002861", "l": "regulation of inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905050", "l": "positive regulation of metallopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metallopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032656", "l": "regulation of interleukin-13 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-13 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018943", "l": "organotin metabolic process", "d": ["The chemical reactions and pathways involving organotin, an organic compound containing a tin atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060321", "l": "acceptance of pollen", "d": ["The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002070", "l": "epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051597", "l": "response to methylmercury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090238", "l": "positive regulation of arachidonic acid secretion", "d": ["Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044075", "l": "modulation by symbiont of host vacuole organization", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075222", "l": "sporangium germination", "d": ["The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0140056", "l": "organelle localization by membrane tethering", "d": ["The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905124", "l": "negative regulation of glucosylceramidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0060428", "l": "lung epithelium development", "d": ["The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010758", "l": "regulation of macrophage chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070172", "l": "positive regulation of tooth mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036292", "l": "DNA rewinding", "d": ["The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905537", "l": "positive regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905653", "l": "positive regulation of artery morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of artery morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.583435665559108", "identifiers": [{"i": "GO:0012501", "l": "programmed cell death", "d": ["A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904358", "l": "positive regulation of telomere maintenance via telomere lengthening", "d": ["Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048245", "l": "eosinophil chemotaxis", "d": ["The movement of an eosinophil in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2001307", "l": "xanthone-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a xanthone-containing compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014021", "l": "secondary neural tube formation", "d": ["The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009597", "l": "detection of virus", "d": ["The series of events in which a stimulus from a virus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904795", "l": "positive regulation of euchromatin binding", "d": ["Any process that activates or increases the frequency, rate or extent of euchromatin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904842", "l": "response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903603", "l": "thermospermine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thermospermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0071825", "l": "protein-lipid complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048204", "l": "vesicle targeting, inter-Golgi cisterna", "d": ["The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006388", "l": "tRNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900487", "l": "regulation of [2Fe-2S] cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006617", "l": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "d": ["The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006316", "l": "movement of group I intron", "d": ["Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071651", "l": "positive regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061965", "l": "positive regulation of entry into reproductive diapause", "d": ["Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002098", "l": "tRNA wobble uridine modification", "d": ["The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.803933740867301", "identifiers": [{"i": "GO:0062012", "l": "regulation of small molecule metabolic process", "d": ["Any process that modulates the rate, frequency or extent of a small molecule metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0072337", "l": "modified amino acid transport", "d": ["The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034516", "l": "response to vitamin B6", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900331", "l": "negative regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900758", "l": "negative regulation of D-amino-acid oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990636", "l": "reproductive senescence", "d": ["A life cycle stage during which the reproductive capacity and fitness of an organism declines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000221", "l": "negative regulation of pseudohyphal growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042837", "l": "D-glucarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030721", "l": "spectrosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080021", "l": "response to benzoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046648", "l": "positive regulation of gamma-delta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002295", "l": "T-helper cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007381", "l": "specification of segmental identity, labial segment", "d": ["The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061303", "l": "cornea development in camera-type eye", "d": ["The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010201", "l": "response to continuous far red light stimulus by the high-irradiance response system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106025", "l": "positive regulation of pupariation", "d": ["Any process that activates or increases the frequency, rate or extent of onset of pupariation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052317", "l": "camalexin metabolic process", "d": ["The chemical reactions and pathways involving camalexin, an indole phytoalexin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040038", "l": "polar body extrusion after meiotic divisions", "d": ["The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0002026", "l": "regulation of the force of heart contraction", "d": ["Any process that modulates the extent of heart contraction, changing the force with which blood is propelled."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0006113", "l": "fermentation", "d": ["The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0046629", "l": "gamma-delta T cell activation", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904980", "l": "positive regulation of endosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of endosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009090", "l": "homoserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018353", "l": "protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine", "d": ["The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060568", "l": "regulation of peptide hormone processing", "d": ["Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042596", "l": "fear response", "d": ["The response of an organism to a perceived external threat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071419", "l": "cellular response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901799", "l": "negative regulation of proteasomal protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901553", "l": "malonic acid transmembrane transport", "d": ["The directed movement of malonic acid across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0044504", "l": "modulation of receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a receptor in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0051494", "l": "negative regulation of cytoskeleton organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140456", "l": "initial meiotic spindle pole body separation", "d": ["The release of duplicated meiotic spindle pole bodies (SPBs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905595", "l": "regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061067", "l": "negative regulation of dauer larval development", "d": ["Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0071715", "l": "icosanoid transport", "d": ["The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009715", "l": "chalcone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042882", "l": "L-arabinose transmembrane transport", "d": ["The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021731", "l": "trigeminal motor nucleus development", "d": ["The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046350", "l": "galactosaminoglycan metabolic process", "d": ["The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034428", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'", "d": ["The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060880", "l": "cell morphogenesis involved in semicircular canal fusion", "d": ["The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090164", "l": "asymmetric Golgi ribbon formation", "d": ["The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141030", "l": "perturbation by symbiont of host actin cytoskeleton via filamentous actin depolymerization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905704", "l": "positive regulation of inhibitory synapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003046", "l": "regulation of systemic arterial blood pressure by stress relaxation", "d": ["The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0006140", "l": "regulation of nucleotide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000414", "l": "negative regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019758", "l": "glycosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042818", "l": "pyridoxamine metabolic process", "d": ["The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010397", "l": "apiogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902820", "l": "1-undecene metabolic process", "d": ["The chemical reactions and pathways involving 1-undecene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021822", "l": "negative regulation of cell motility involved in cerebral cortex radial glia guided migration", "d": ["The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006046", "l": "N-acetylglucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905065", "l": "positive regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032058", "l": "positive regulation of translational initiation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071484", "l": "cellular response to light intensity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061086", "l": "negative regulation of histone H3-K27 methylation", "d": ["Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021552", "l": "midbrain-hindbrain boundary structural organization", "d": ["The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903087", "l": "mitotic spindle pole body duplication", "d": ["Any spindle pole body duplication that is involved in the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051612", "l": "negative regulation of serotonin uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072245", "l": "metanephric glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904541", "l": "fungal-type cell wall disassembly involved in conjugation with cellular fusion", "d": ["Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120072", "l": "positive regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990884", "l": "RNA acetylation", "d": ["The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905644", "l": "regulation of FACT complex assembly", "d": ["Any process that modulates the frequency, rate or extent of FACT complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048768", "l": "root hair cell tip growth", "d": ["Localized growth of a plant root hair tip by extension of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903553", "l": "positive regulation of extracellular exosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903242", "l": "regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060084", "l": "synaptic transmission involved in micturition", "d": ["The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048158", "l": "oogonium stage", "d": ["The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046449", "l": "creatinine metabolic process", "d": ["The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901541", "l": "ent-pimara-8(14),15-diene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000321", "l": "positive regulation of T-helper 17 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120181", "l": "focal adhesion disassembly", "d": ["The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0033750", "l": "ribosome localization", "d": ["A process in which a ribosome is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051973", "l": "positive regulation of telomerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002836", "l": "positive regulation of response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of a response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019429", "l": "fluorene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902732", "l": "positive regulation of chondrocyte proliferation", "d": ["Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000698", "l": "positive regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0044788", "l": "modulation by host of viral process", "d": ["A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903863", "l": "P granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a P granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060742", "l": "epithelial cell differentiation involved in prostate gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0022013", "l": "pallium cell proliferation in forebrain", "d": ["The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090111", "l": "regulation of COPII vesicle uncoating", "d": ["Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035222", "l": "wing disc pattern formation", "d": ["The process giving rise to the pattern of cell differentiation in the wing imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097390", "l": "chemokine (C-X-C motif) ligand 12 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990273", "l": "snRNA capping", "d": ["The addition of a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA). Capping 7SK RNA stabilizes it."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902241", "l": "copal-8-ol diphosphate(3-) metabolic process", "d": ["The chemical reactions and pathways involving copal-8-ol diphosphate(3-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010789", "l": "meiotic sister chromatid cohesion involved in meiosis I", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015910", "l": "long-chain fatty acid import into peroxisome", "d": ["The directed movement of a long-chain fatty acid into a peroxisome. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.945349939901874", "identifiers": [{"i": "GO:0032941", "l": "secretion by tissue", "d": ["The controlled release of a substance by a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000894", "l": "cellotriose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellotriose."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003208", "l": "cardiac ventricle morphogenesis", "d": ["The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003152", "l": "morphogenesis of an epithelial fold involved in embryonic heart tube formation", "d": ["The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006481", "l": "C-terminal protein methylation", "d": ["The methylation of the C-terminal amino acid of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001980", "l": "regulation of systemic arterial blood pressure by ischemic conditions", "d": ["The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033090", "l": "positive regulation of extrathymic T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099515", "l": "actin filament-based transport", "d": ["The transport of organelles or other particles from one location in the cell to another along actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904575", "l": "positive regulation of selenocysteine insertion sequence binding", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062110", "l": "negative regulation of DNA recombinase disassembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:1990868", "l": "response to chemokine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0051180", "l": "vitamin transport", "d": ["The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0060012", "l": "synaptic transmission, glycinergic", "d": ["The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060650", "l": "epithelial cell proliferation involved in mammary gland bud elongation", "d": ["The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062090", "l": "positive regulation of taurine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of taurine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033566", "l": "gamma-tubulin complex localization", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905596", "l": "negative regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044147", "l": "negative regulation of formation of structure involved in a symbiotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905572", "l": "ganglioside GM1 transport to membrane", "d": ["The directed movement of ganglioside GM1 to membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032531", "l": "regulation of follicle cell microvillus organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045210", "l": "FasL biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.387656307797414", "identifiers": [{"i": "GO:0006873", "l": "intracellular monoatomic ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044734", "l": "envenomation resulting in positive regulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098777", "l": "protein secretion by the type VIII secretion system", "d": ["Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071938", "l": "vitamin A transport", "d": ["The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990950", "l": "metaphase/anaphase transition of meiosis II", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034156", "l": "negative regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902383", "l": "11-oxo-beta-amyrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061760", "l": "antifungal innate immune response", "d": ["An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010550", "l": "regulation of PSII associated light-harvesting complex II catabolic process", "d": ["Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046294", "l": "formaldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006739", "l": "NADP metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140270", "l": "gluconate import across plasma membrane", "d": ["The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900894", "l": "negative regulation of tridecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060383", "l": "positive regulation of DNA strand elongation", "d": ["Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0030858", "l": "positive regulation of epithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097215", "l": "negative regulation of lysosomal membrane permeability", "d": ["Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900765", "l": "emericellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032461", "l": "positive regulation of protein oligomerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein oligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905278", "l": "positive regulation of epithelial tube formation", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial tube formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070432", "l": "regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000729", "l": "positive regulation of mesenchymal cell proliferation involved in ureter development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140591", "l": "nuclear envelope budding", "d": ["The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900193", "l": "regulation of oocyte maturation", "d": ["Any process that modulates the frequency, rate or extent of oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018967", "l": "tetrachloroethylene metabolic process", "d": ["The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. 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frequency, rate or extent of cytoplasmic transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035022", "l": "positive regulation of Rac protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0030640", "l": "polyketide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097010", "l": "eukaryotic translation initiation factor 4F complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0009629", "l": "response to gravity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010707", "l": "globoside biosynthetic process via lactosylceramide", "d": ["The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000450", "l": "negative regulation of CD8-positive, alpha-beta T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018067", "l": "peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002332", "l": "transitional stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903061", "l": "positive regulation of protein lipidation", "d": ["Any process that activates or increases the frequency, rate or extent of protein lipidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036303", "l": "lymph vessel morphogenesis", "d": ["The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904800", "l": "negative regulation of neuron remodeling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019507", "l": "pyridine metabolic process", "d": ["The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060438", "l": "trachea development", "d": ["The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0007447", "l": "imaginal disc pattern formation", "d": ["The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046044", "l": "TMP metabolic process", "d": ["The chemical reactions and pathways involving TMP, ribosylthymine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0070252", "l": "actin-mediated cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903587", "l": "regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097692", "l": "histone H3-K4 monomethylation", "d": ["The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0022416", "l": "chaeta development", "d": ["The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072737", "l": "response to diamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902938", "l": "regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:2000737", "l": "negative regulation of stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034728", "l": "nucleosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051850", "l": "acquisition of nutrients from symbiont", "d": ["The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090156", "l": "intracellular sphingolipid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045847", "l": "negative regulation of nitrogen utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0034102", "l": "erythrocyte clearance", "d": ["The selective elimination of erythrocytes from the body by autoregulatory mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0000724", "l": "double-strand break repair via homologous recombination", "d": ["The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051137", "l": "negative regulation of NK T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0007309", "l": "oocyte axis specification", "d": ["The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072271", "l": "metanephric short descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032385", "l": "positive regulation of intracellular cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062210", "l": "shoot regeneration", "d": ["The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021739", "l": "mesencephalic trigeminal nucleus development", "d": ["The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903542", "l": "negative regulation of exosomal secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003312", "l": "pancreatic PP cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035008", "l": "positive regulation of melanization defense response", "d": ["Any process that increases the rate or extent of the melanization defense response during injury or invasion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039521", "l": "suppression by virus of host autophagy", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903892", "l": "negative regulation of ATF6-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045465", "l": "R8 cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048388", "l": "endosomal lumen acidification", "d": ["Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010063", "l": "positive regulation of trichoblast fate specification", "d": ["Any process that induces or promotes trichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030910", "l": "olfactory placode formation", "d": ["The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001035", "l": "regulation of tongue muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060862", "l": "negative regulation of floral organ abscission", "d": ["Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070716", "l": "mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication", "d": ["A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003112", "l": "positive regulation of heart rate by neuronal epinephrine", "d": ["The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002255", "l": "tissue kallikrein-kinin cascade", "d": ["A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061524", "l": "central canal development", "d": ["The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060015", "l": "granulosa cell fate commitment", "d": ["The cell fate commitment of precursor cells that will become granulosa cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001815", "l": "positive regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035133", "l": "post-embryonic caudal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071583", "l": "negative regulation of zinc ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905656", "l": "positive regulation of artery smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0061004", "l": "pattern specification involved in kidney development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018238", "l": "peptidyl-lysine carboxyethylation", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0098734", "l": "macromolecule depalmitoylation", "d": ["The removal of palymitoyl groups from a macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051491", "l": "positive regulation of filopodium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901905", "l": "response to tamsulosin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060667", "l": "branch elongation involved in salivary gland morphogenesis", "d": ["The differential growth of the salivary branches along their axis, resulting in the growth of a branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0016239", "l": "positive regulation of macroautophagy", "d": ["Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042662", "l": "negative regulation of mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035317", "l": "imaginal disc-derived wing hair organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061273", "l": "mesonephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009830", "l": "cell wall modification involved in abscission", "d": ["A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072576", "l": "liver morphogenesis", "d": ["The process in which the anatomical structures of the liver are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.75272396535307", "identifiers": [{"i": "GO:1990151", "l": "protein localization to cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location at the cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905569", "l": "negative regulation of ferrichrome biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048903", "l": "anterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140970", "l": "AIM2 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the AIM2 inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048804", "l": "imaginal disc-derived female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized from the genital disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901196", "l": "positive regulation of calcium-mediated signaling involved in cellular response to salt stress", "d": ["Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051560", "l": "mitochondrial calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044628", "l": "positive regulation of complement activation, classical pathway in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901762", "l": "oxytetracycline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oxytetracycline."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060292", "l": "long-term synaptic depression", "d": ["A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045692", "l": "negative regulation of embryo sac central cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0090329", "l": "regulation of DNA-templated DNA replication", "d": ["Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014864", "l": "detection of muscle activity", "d": ["The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019043", "l": "establishment of viral latency", "d": ["A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008365", "l": "adult chitin-based cuticle development", "d": ["Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019093", "l": "mitochondrial RNA localization", "d": ["Any process in which mitochondrial RNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051974", "l": "negative regulation of telomerase activity", "d": ["Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000790", "l": "regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905680", "l": "regulation of innate immunity memory response", "d": ["Any process that modulates the frequency, rate or extent of innate immunity memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075504", "l": "macropinosomal membrane permeabilization involved in viral entry into host cell", "d": ["Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903227", "l": "xanthosine metabolic process", "d": ["The chemical reactions and pathways involving xanthosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048083", "l": "negative regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070656", "l": "mechanoreceptor differentiation involved in mechanosensory epithelium regeneration", "d": ["Differentiation of new mechanoreceptors to replace those lost or destroyed by injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000841", "l": "negative regulation of dehydroepiandrosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018138", "l": "peptide cross-linking via L-serine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0045445", "l": "myoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901613", "l": "negative regulation of terminal button organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000914", "l": "positive regulation of galactoglucomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.483555723501368", "identifiers": [{"i": "GO:0072657", "l": "protein localization to membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location in a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080035", "l": "2-hydroxy-but-3-enyl glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035753", "l": "maintenance of DNA trinucleotide repeats", "d": ["Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070078", "l": "histone H3-R2 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990743", "l": "protein sialylation", "d": ["A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035349", "l": "coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045231", "l": "slime layer organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090427", "l": "activation of meiosis", "d": ["Any process that starts the inactive process of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075011", "l": "positive regulation of germ tube formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048213", "l": "Golgi vesicle prefusion complex stabilization", "d": ["The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.588454143880355", "identifiers": [{"i": "GO:0030900", "l": "forebrain development", "d": ["The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032344", "l": "regulation of aldosterone metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000520", "l": "regulation of immunological synapse formation", "d": ["Any process that modulates the frequency, rate or extent of immunological synapse formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003219", "l": "cardiac right ventricle formation", "d": ["The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0007340", "l": "acrosome reaction", "d": ["The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046039", "l": "GTP metabolic process", "d": ["The chemical reactions and pathways involving GTP, guanosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038101", "l": "sequestering of nodal from receptor via nodal binding", "d": ["Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0086091", "l": "regulation of heart rate by cardiac conduction", "d": ["A cardiac conduction process that modulates the frequency or rate of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070163", "l": "regulation of adiponectin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062025", "l": "regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070459", "l": "prolactin secretion", "d": ["The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032325", "l": "molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903433", "l": "regulation of constitutive secretory pathway", "d": ["Any process that modulates the frequency, rate or extent of constitutive secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001120", "l": "protein-DNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0001934", "l": "positive regulation of protein phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.495242488514975", "identifiers": [{"i": "GO:0015698", "l": "inorganic anion transport", "d": ["The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018406", "l": "protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan", "d": ["The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061376", "l": "mammillotegmental axonal tract development", "d": ["The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032073", "l": "negative regulation of restriction endodeoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0052055", "l": "modulation by symbiont of host molecular function", "d": ["The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042316", "l": "penicillin metabolic process", "d": ["The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120326", "l": "appressorium-mediated entry into host", "d": ["Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042784", "l": "evasion of host immune response via modulation of host complement system", "d": ["Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0000212", "l": "meiotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044738", "l": "negative regulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015840", "l": "urea transport", "d": ["The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900963", "l": "negative regulation of methanophenazine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045683", "l": "negative regulation of epidermis development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0050767", "l": "regulation of neurogenesis", "d": ["Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075306", "l": "regulation of conidium formation", "d": ["Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900991", "l": "scopolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of scopolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099098", "l": "microtubule polymerization based movement", "d": ["The movement of a cellular component as a result of microtubule polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075196", "l": "adhesion of symbiont haustorium mother cell to host", "d": ["The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035564", "l": "regulation of kidney size", "d": ["Any process that modulates the size of a kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000442", "l": "positive regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0006413", "l": "translational initiation", "d": ["The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071525", "l": "pyrrolysine metabolic process", "d": ["The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061233", "l": "mesonephric glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900952", "l": "positive regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006623", "l": "protein targeting to vacuole", "d": ["The process of directing proteins towards the vacuole, usually using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0042745", "l": "circadian sleep/wake cycle", "d": ["The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900140", "l": "regulation of seedling development", "d": ["Any process that modulates the frequency, rate or extent of seedling development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071373", "l": "cellular response to luteinizing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0030865", "l": "cortical cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021968", "l": "corticospinal neuron axon guidance through the internal capsule", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905067", "l": "negative regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071608", "l": "macrophage inflammatory protein-1 alpha production", "d": ["The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035847", "l": "uterine epithelium development", "d": ["The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098006", "l": "viral DNA genome packaging, headful", "d": ["The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036049", "l": "peptidyl-lysine desuccinylation", "d": ["The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090187", "l": "positive regulation of pancreatic juice secretion", "d": ["Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031427", "l": "response to methotrexate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140043", "l": "lipid droplet localization to prospore membrane leading edge", "d": ["Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905041", "l": "regulation of epithelium regeneration", "d": ["Any process that modulates the frequency, rate or extent of epithelium regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019802", "l": "cyclization of glutamine involved in intein-mediated protein splicing", "d": ["The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140972", "l": "negative regulation of AIM2 inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043123", "l": "positive regulation of canonical NF-kappaB signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.618676235870325", "identifiers": [{"i": "GO:0040011", "l": "locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904020", "l": "regulation of G protein-coupled receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006064", "l": "glucuronate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055023", "l": "positive regulation of cardiac muscle tissue growth", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014056", "l": "regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903761", "l": "negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006925", "l": "inflammatory cell apoptotic process", "d": ["Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048933", "l": "afferent axon development in posterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042077", "l": "protein phosphate-linked glycosylation via serine", "d": ["The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034231", "l": "islet amyloid polypeptide processing", "d": ["The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0101025", "l": "nuclear membrane biogenesis", "d": ["The process in which a nuclear membrane is synthesized, aggregates, and bonds together."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002427", "l": "mucosal tolerance induction", "d": ["Tolerance induction taking place in the mucosal tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003096", "l": "renal sodium ion transport", "d": ["The directed movement of sodium ions (Na+) by the renal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051547", "l": "regulation of keratinocyte migration", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085001", "l": "formation of stylet for nutrient acquisition", "d": ["The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010961", "l": "intracellular magnesium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035281", "l": "pre-miRNA export from nucleus", "d": ["Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033517", "l": "myo-inositol hexakisphosphate metabolic process", "d": ["The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0090092", "l": "regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002787", "l": "negative regulation of antibacterial peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900919", "l": "positive regulation of octadecene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of octadecene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018153", "l": "isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine", "d": ["The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0000394", "l": "RNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097656", "l": "cell-cell self recognition", "d": ["A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010073", "l": "meristem maintenance", "d": ["Any process involved in maintaining the identity, size and shape of a meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090372", "l": "positive regulation of glycerol transport", "d": ["Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075324", "l": "negative regulation of oomycete sporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034344", "l": "regulation of type III interferon production", "d": ["Any process that modulates the frequency, rate, or extent of type III interferon production. 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A determinate inflorescence is one that can produce an undefined number of floral meristems."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043353", "l": "enucleate erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0051384", "l": "response to glucocorticoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045864", "l": "positive regulation of pteridine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048909", "l": "anterior lateral line nerve development", "d": ["The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901154", "l": "paromomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of paromomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0010469", "l": "regulation of signaling receptor activity", "d": ["Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014728", "l": "regulation of the force of skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900070", "l": "negative regulation of cellular hyperosmotic salinity response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903266", "l": "regulation of ornithine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ornithine catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1904688", "l": "regulation of cytoplasmic translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.806205446421131", "identifiers": [{"i": "GO:0006259", "l": "DNA metabolic process", "d": ["Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.820827815612489", "identifiers": [{"i": "GO:0051130", "l": "positive regulation of cellular component organization", "d": ["Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018389", "l": "N-terminal peptidyl-valine deamination", "d": ["The deamination of the N-terminal valine residue of a protein to form isobutyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110069", "l": "syncytial embryo cellularization", "d": ["The separation of a syncytial embryo into individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0050964", "l": "detection of electrical stimulus involved in electroception", "d": ["The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0009306", "l": "protein secretion", "d": ["The controlled release of proteins from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.441195081532641", "identifiers": [{"i": "GO:0051216", "l": "cartilage development", "d": ["The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902171", "l": "regulation of tocopherol cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of tocopherol cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007349", "l": "cellularization", "d": ["The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901510", "l": "(-)-microperfuranone metabolic process", "d": ["The chemical reactions and pathways involving (-)-microperfuranone."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032907", "l": "transforming growth factor beta3 production", "d": ["The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902010", "l": "negative regulation of translation in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000411", "l": "negative regulation of thymocyte migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002894", "l": "positive regulation of type II hypersensitivity", "d": ["Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0000955", "l": "amino acid catabolic process via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002597", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0031110", "l": "regulation of microtubule polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001879", "l": "detection of yeast", "d": ["The series of events in which a stimulus from a yeast is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033700", "l": "phospholipid efflux", "d": ["The directed movement of a phospholipid out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019069", "l": "viral capsid assembly", "d": ["The assembly of a virus capsid from its protein subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0150155", "l": "interleukin-34 production", "d": ["The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0009081", "l": "branched-chain amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0014841", "l": "skeletal muscle satellite cell proliferation", "d": ["The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071329", "l": "cellular response to sucrose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036145", "l": "dendritic cell homeostasis", "d": ["The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.086908212148579", "identifiers": [{"i": "GO:0050878", "l": "regulation of body fluid levels", "d": ["Any process that modulates the levels of body fluids."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006086", "l": "acetyl-CoA biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052023", "l": "modulation by symbiont of salicylic acid levels in host", "d": ["The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032626", "l": "interleukin-22 production", "d": ["The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045443", "l": "juvenile hormone secretion", "d": ["The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018984", "l": "naphthalenesulfonate metabolic process", "d": ["The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042743", "l": "hydrogen peroxide metabolic process", "d": ["The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000826", "l": "regulation of heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046642", "l": "negative regulation of alpha-beta T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0042098", "l": "T cell proliferation", "d": ["The expansion of a T cell population by cell division. Follows T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032237", "l": "activation of store-operated calcium channel activity", "d": ["A process that initiates the activity of an inactive store-operated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006104", "l": "succinyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051775", "l": "response to redox state", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002878", "l": "negative regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0007015", "l": "actin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0086068", "l": "Purkinje myocyte to ventricular cardiac muscle cell communication", "d": ["The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060900", "l": "embryonic camera-type eye formation", "d": ["The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030253", "l": "protein secretion by the type I secretion system", "d": ["The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905779", "l": "positive regulation of exonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048340", "l": "paraxial mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the paraxial mesoderm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0021801", "l": "cerebral cortex radial glia-guided migration", "d": ["The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160001", "l": "extrasynaptic signaling via GABA", "d": ["Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098720", "l": "succinate import across plasma membrane", "d": ["The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050665", "l": "hydrogen peroxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070799", "l": "regulation of conidiophore stalk development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039644", "l": "suppression by virus of host NF-kappaB cascade", "d": ["Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.881033081418458", "identifiers": [{"i": "GO:0009914", "l": "hormone transport", "d": ["The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2001279", "l": "regulation of unsaturated fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032952", "l": "regulation of (1->3)-beta-D-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002852", "l": "regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070474", "l": "positive regulation of uterine smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of uterine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050883", "l": "musculoskeletal movement, spinal reflex action", "d": ["Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. 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The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000255", "l": "negative regulation of male germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000604", "l": "negative regulation of secondary growth", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903629", "l": "positive regulation of dUTP diphosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902550", "l": "lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis", "d": ["Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902875", "l": "regulation of embryonic pattern specification", "d": ["Any process that modulates the frequency, rate or extent of embryonic pattern specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042620", "l": "poly(3-hydroxyalkanoate) metabolic process", "d": ["The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017195", "l": "N-terminal peptidyl-lysine N2-acetylation", "d": ["The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043409", "l": "negative regulation of MAPK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021737", "l": "emboliform nucleus development", "d": ["The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072238", "l": "metanephric long nephron development", "d": ["The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045742", "l": "positive regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009440", "l": "cyanate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019680", "l": "L-methylmalonyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046771", "l": "viral budding from inner nuclear membrane", "d": ["The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001040", "l": "positive regulation of cellular response to drug", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904828", "l": "positive regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901495", "l": "negative regulation of cysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900335", "l": "positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0034763", "l": "negative regulation of transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051660", "l": "establishment of centrosome localization", "d": ["The directed movement of the centrosome to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901339", "l": "regulation of store-operated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of store-operated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071803", "l": "positive regulation of podosome assembly", "d": ["Any process that activates or increases the rate or extent of podosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.800603314158678", "identifiers": [{"i": "GO:0120254", "l": "olefinic compound metabolic process", "d": ["The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.681872163386743", "identifiers": [{"i": "GO:0002438", "l": "acute inflammatory response to antigenic stimulus", "d": ["An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090118", "l": "receptor-mediated endocytosis involved in cholesterol transport", "d": ["A receptor-mediated endocytosis process involved in intracellular cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905938", "l": "positive regulation of germ cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043058", "l": "regulation of backward locomotion", "d": ["Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0060828", "l": "regulation of canonical Wnt signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071644", "l": "negative regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033510", "l": "luteolin metabolic process", "d": ["The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043705", "l": "cyanophycin metabolic process", "d": ["The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2001115", "l": "methanopterin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a methanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903329", "l": "regulation of iron-sulfur cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019253", "l": "reductive pentose-phosphate cycle", "d": ["The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009801", "l": "cinnamic acid ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048854", "l": "brain morphogenesis", "d": ["The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062211", "l": "root regeneration", "d": ["The the regeneration process by which a damaged or lost root regrows or re-differentiates. 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The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032731", "l": "positive regulation of interleukin-1 beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106060", "l": "regulation of exit from meiosis", "d": ["Any process that modulates the frequency, rate or extent of exit from mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:1902292", "l": "cell cycle DNA replication initiation", "d": ["Any DNA replication initiation that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021825", "l": "substrate-dependent cerebral cortex tangential migration", "d": ["The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0031124", "l": "mRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an mRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140021", "l": "mitochondrial ADP transmembrane transport", "d": ["The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035234", "l": "ectopic germ cell programmed cell death", "d": ["Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009177", "l": "pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060669", "l": "embryonic placenta morphogenesis", "d": ["The process in which the embryonic placenta is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901557", "l": "response to fenofibrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048928", "l": "posterior lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901438", "l": "negative regulation of toluene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.788005074184341", "identifiers": [{"i": "GO:0055086", "l": "nucleobase-containing small molecule metabolic process", "d": ["The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903949", "l": "positive regulation of atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032698", "l": "negative regulation of interleukin-15 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030325", "l": "adrenal gland development", "d": ["The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060508", "l": "lung basal cell differentiation", "d": ["The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903659", "l": "regulation of complement-dependent cytotoxicity", "d": ["Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905532", "l": "regulation of leucine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of leucine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990536", "l": "phosphoenolpyruvate transmembrane import into Golgi lumen", "d": ["The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097178", "l": "ruffle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098530", "l": "positive regulation of strand invasion", "d": ["Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1905031", "l": "regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034058", "l": "endosomal vesicle fusion", "d": ["The homotypic fusion of endocytic vesicles to form or add to an early endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015990", "l": "electron transport coupled proton transport", "d": ["The transport of protons against an electrochemical gradient, using energy from electron transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019332", "l": "aerobic respiration, using nitrite as electron donor", "d": ["The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0050960", "l": "detection of temperature stimulus involved in thermoception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048451", "l": "petal formation", "d": ["The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003175", "l": "tricuspid valve development", "d": ["The progression of the tricuspid valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.164334333752237", "identifiers": [{"i": "GO:0043473", "l": "pigmentation", "d": ["The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0010454", "l": "negative regulation of cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0098930", "l": "axonal transport", "d": ["The directed movement of organelles or molecules along microtubules in axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099052", "l": "vesicle scission involved in clathrin-mediated endocytosis", "d": ["The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043496", "l": "regulation of protein homodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099632", "l": "protein transport within plasma membrane", "d": ["A process in which protein is transported from one region of the plasma membrane to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018104", "l": "peptidoglycan-protein cross-linking", "d": ["The process of covalently linking peptidoglycan (murein) to proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035266", "l": "meristem growth", "d": ["The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901110", "l": "actinorhodin metabolic process", "d": ["The chemical reactions and pathways involving actinorhodin."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.969489883774216", "identifiers": [{"i": "GO:0010638", "l": "positive regulation of organelle organization", "d": ["Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140529", "l": "CMG complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015763", "l": "N-acetylgalactosamine transport", "d": ["The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048626", "l": "myoblast fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019574", "l": "sucrose catabolic process via 3'-ketosucrose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034238", "l": "macrophage fusion", "d": ["The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061584", "l": "orexin secretion", "d": ["The controlled release of orexin from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902924", "l": "poly(hydroxyalkanoate) biosynthetic process from glucose", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904033", "l": "negative regulation of t-SNARE clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060376", "l": "positive regulation of mast cell differentiation", "d": ["Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901440", "l": "poly(hydroxyalkanoate) metabolic process", "d": ["The chemical reactions and pathways involving poly(hydroxyalkanoate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0045664", "l": "regulation of neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901809", "l": "capsanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of capsanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901234", "l": "positive regulation of convergent extension involved in axis elongation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060855", "l": "venous endothelial cell migration involved in lymph vessel development", "d": ["The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036223", "l": "cellular response to adenine starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060575", "l": "intestinal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0007500", "l": "mesodermal cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071952", "l": "conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA", "d": ["The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031121", "l": "equatorial microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021624", "l": "oculomotor nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902575", "l": "protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly", "d": ["Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051463", "l": "negative regulation of cortisol secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002842", "l": "positive regulation of T cell mediated immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010536", "l": "positive regulation of activation of Janus kinase activity", "d": ["Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043048", "l": "dolichyl monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005986", "l": "sucrose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002936", "l": "bradykinin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044526", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine", "d": ["The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071594", "l": "thymocyte aggregation", "d": ["The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901595", "l": "response to hesperadin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0101027", "l": "optical nerve axon regeneration", "d": ["The regrowth of axons of the optical nerve following their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0051458", "l": "corticotropin secretion", "d": ["The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0050869", "l": "negative regulation of B cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:0003205", "l": "cardiac chamber development", "d": ["The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002457", "l": "T cell antigen processing and presentation", "d": ["The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902722", "l": "positive regulation of prolactin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of prolactin secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0002475", "l": "antigen processing and presentation via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905372", "l": "ceramide phosphoethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000149", "l": "negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902183", "l": "regulation of shoot apical meristem development", "d": ["Any process that modulates the frequency, rate or extent of shoot apical meristem development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002373", "l": "plasmacytoid dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a plasmacytoid dendritic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045464", "l": "R8 cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035352", "l": "NAD transmembrane transport", "d": ["The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0051580", "l": "regulation of neurotransmitter uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903543", "l": "positive regulation of exosomal secretion", "d": ["Any process that activates or increases the frequency, rate or extent of exosomal secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009773", "l": "photosynthetic electron transport in photosystem I", "d": ["A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097185", "l": "cellular response to azide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015762", "l": "rhamnose transmembrane transport", "d": ["The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030543", "l": "2-micrometer plasmid partitioning", "d": ["The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060582", "l": "cell fate determination involved in pattern specification", "d": ["A process involved in commitment of a cell to a fate in a developmental field. 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The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0006714", "l": "sesquiterpenoid metabolic process", "d": ["The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901117", "l": "cephamycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cephamycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036225", "l": "cellular response to vitamin B1 starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044827", "l": "modulation by host of viral genome replication", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001697", "l": "histamine-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002448", "l": "mast cell mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:1902622", "l": "regulation of neutrophil migration", "d": ["Any process that modulates the frequency, rate or extent of neutrophil migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051564", "l": "positive regulation of smooth endoplasmic reticulum calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0031365", "l": "N-terminal protein amino acid modification", "d": ["The alteration of the N-terminal amino acid residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019612", "l": "4-toluenecarboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055113", "l": "epiboly involved in gastrulation with mouth forming second", "d": ["The expansion of one cell sheet over other cells involved in deuterostomic gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0019080", "l": "viral gene expression", "d": ["A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080060", "l": "integument development", "d": ["The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060946", "l": "cardiac blood vessel endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. 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Generally fish have one or two dorsal fins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902946", "l": "protein localization to early endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an early endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021925", "l": "cerebellar Purkinje cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090176", "l": "microtubule cytoskeleton organization involved in establishment of planar polarity", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120309", "l": "cilium attachment to cell body", "d": ["A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099532", "l": "synaptic vesicle endosomal processing", "d": ["The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032748", "l": "positive regulation of interleukin-24 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-24 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990736", "l": "regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036530", "l": "protein deglycation, methylglyoxal removal", "d": ["The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2001023", "l": "regulation of response to drug", "d": ["Any process that modulates the frequency, rate or extent of response to drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902734", "l": "regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:2001057", "l": "reactive nitrogen species metabolic process", "d": ["The chemical reactions and pathways involving a reactive nitrogen species."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000608", "l": "positive regulation of cell proliferation involved in mesonephros development", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002512", "l": "central T cell tolerance induction", "d": ["Tolerance induction of T cells in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002804", "l": "positive regulation of antifungal peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antifungal peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002647", "l": "negative regulation of central tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1900424", "l": "regulation of defense response to bacterium", "d": ["Any process that modulates the frequency, rate or extent of defense response to bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034144", "l": "negative regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060088", "l": "auditory receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070639", "l": "vitamin D2 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000239", "l": "negative regulation of tRNA export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903025", "l": "regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062056", "l": "compound eye pigment cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903941", "l": "negative regulation of respiratory gaseous exchange", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052460", "l": "modulation of nutrient release by symbiont", "d": ["Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905805", "l": "excitatory synapse pruning", "d": ["The disaggregation of an excitatory synapse into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.865219057600569", "identifiers": [{"i": "GO:0032259", "l": "methylation", "d": ["The process in which a methyl group is covalently attached to a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900356", "l": "positive regulation of methanofuran metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019402", "l": "galactitol metabolic process", "d": ["The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032105", "l": "negative regulation of response to extracellular stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052787", "l": "alpha-linked polysaccharide catabolism to maltopentaose", "d": ["The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902078", "l": "positive regulation of lateral motor column neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1904427", "l": "positive regulation of calcium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042208", "l": "propylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900836", "l": "positive regulation of emericellin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903580", "l": "positive regulation of ATP metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ATP metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060352", "l": "cell adhesion molecule production", "d": ["The appearance of a cell adhesion molecule due to biosynthesis or secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033536", "l": "ajugose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009223", "l": "pyrimidine deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007395", "l": "dorsal closure, spreading of leading edge cells", "d": ["Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010400", "l": "rhamnogalacturonan I side chain metabolic process", "d": ["The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050999", "l": "regulation of nitric-oxide synthase activity", "d": ["Any process that modulates the activity of the enzyme nitric-oxide synthase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905903", "l": "negative regulation of mesoderm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098673", "l": "inhibition of host DNA replication by virus", "d": ["Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071036", "l": "nuclear polyadenylation-dependent snoRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021790", "l": "chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099559", "l": "maintenance of alignment of postsynaptic density and presynaptic active zone", "d": ["The process by which alignment between postsynaptic density and presynaptic active zone is maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006245", "l": "TDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904178", "l": "negative regulation of adipose tissue development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0052167", "l": "perturbation of host innate immune response", "d": ["A process in which an organism effects a change that affects the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060706", "l": "cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0042178", "l": "xenobiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072749", "l": "cellular response to cytochalasin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0042472", "l": "inner ear morphogenesis", "d": ["The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072679", "l": "thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006223", "l": "uracil salvage", "d": ["Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1902275", "l": "regulation of chromatin organization", "d": ["Any process that modulates the frequency, rate or extent of chromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003226", "l": "right ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061875", "l": "negative regulation of hepatic stellate cell contraction", "d": ["Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.6720795298599", "identifiers": [{"i": "GO:0051336", "l": "regulation of hydrolase activity", "d": ["Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050762", "l": "depsipeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006685", "l": "sphingomyelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070634", "l": "transepithelial ammonium transport", "d": ["The directed movement of ammonium ions from one side of an epithelium to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0009061", "l": "anaerobic respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080038", "l": "positive regulation of cytokinin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of cytokinin signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046599", "l": "regulation of centriole replication", "d": ["Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010765", "l": "positive regulation of sodium ion transport", "d": ["Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901824", "l": "delta-carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of delta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090470", "l": "shoot organ boundary specification", "d": ["The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0002208", "l": "somatic diversification of immunoglobulins involved in immune response", "d": ["The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010265", "l": "SCF complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0022900", "l": "electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.945349939901874", "identifiers": [{"i": "GO:0055123", "l": "digestive system development", "d": ["The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001012", "l": "mesenchymal cell differentiation involved in renal system development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904738", "l": "vascular associated smooth muscle cell migration", "d": ["The orderly movement of a vascular associated smooth muscle cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007319", "l": "negative regulation of oskar mRNA translation", "d": ["Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097187", "l": "dentinogenesis", "d": ["The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052201", "l": "response to symbiont defenses", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007534", "l": "gene conversion at mating-type locus", "d": ["The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900157", "l": "regulation of bone mineralization involved in bone maturation", "d": ["Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019436", "l": "sophorosyloxydocosanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002078", "l": "membrane fusion involved in acrosome reaction", "d": ["The fusion of the plasma membrane of the sperm with the outer acrosomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032871", "l": "regulation of karyogamy", "d": ["Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0007593", "l": "chitin-based cuticle sclerotization", "d": ["The process of hardening of a chitin-based cuticle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000042", "l": "negative regulation of double-strand break repair via homologous recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007463", "l": "R2/R5 cell fate commitment", "d": ["The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060114", "l": "vestibular receptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018006", "l": "N-terminal protein amino acid glucuronylation", "d": ["The glucuronylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051655", "l": "maintenance of vesicle location", "d": ["Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:1900674", "l": "olefin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of olefin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051942", "l": "negative regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990832", "l": "slow axonal transport", "d": ["The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060357", "l": "regulation of leucine import", "d": ["Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006148", "l": "inosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1902117", "l": "positive regulation of organelle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of organelle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010526", "l": "retrotransposon silencing", "d": ["Any process that decreases the frequency, rate or extent of retrotransposition. Retrotransposons are a subset of transposable elements that use an RNA intermediate and reverse transcribe themselves into the genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000555", "l": "negative regulation of T-helper 1 cell cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032928", "l": "regulation of superoxide anion generation", "d": ["Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048601", "l": "oocyte morphogenesis", "d": ["The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0016108", "l": "tetraterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903409", "l": "reactive oxygen species biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903690", "l": "negative regulation of wound healing, spreading of epidermal cells", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035743", "l": "CD4-positive, alpha-beta T cell cytokine production", "d": ["Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900867", "l": "sarcinapterin metabolic process", "d": ["The chemical reactions and pathways involving sarcinapterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0052025", "l": "disruption by symbiont of host cell membrane", "d": ["The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0002715", "l": "regulation of natural killer cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010137", "l": "ureide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905590", "l": "fibronectin fibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900694", "l": "positive regulation of (+)-kotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035523", "l": "protein K29-linked deubiquitination", "d": ["A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106384", "l": "dGMP salvage", "d": ["Any process which produces a dGMP from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075321", "l": "oomycete sporangium development", "d": ["The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019541", "l": "propionate metabolic process", "d": ["The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051464", "l": "positive regulation of cortisol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043508", "l": "negative regulation of JUN kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902525", "l": "regulation of protein monoubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein monoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045724", "l": "positive regulation of cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the formation of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902090", "l": "regulation of fumagillin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086074", "l": "Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication", "d": ["The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052319", "l": "regulation of phytoalexin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030644", "l": "intracellular chloride ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000683", "l": "regulation of cellular response to X-ray", "d": ["Any process that modulates the frequency, rate or extent of cellular response to X-ray."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072166", "l": "posterior mesonephric tubule development", "d": ["The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140212", "l": "regulation of long-chain fatty acid import into cell", "d": ["Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120221", "l": "maintenance of ciliary planar beating movement pattern", "d": ["Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0015802", "l": "basic amino acid transport", "d": ["The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0019730", "l": "antimicrobial humoral response", "d": ["An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031154", "l": "culmination involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035724", "l": "CD24 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000848", "l": "positive regulation of corticosteroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901610", "l": "positive regulation of vesicle transport along microtubule", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0006662", "l": "glycerol ether metabolic process", "d": ["The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0031049", "l": "programmed DNA elimination", "d": ["A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0046184", "l": "aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0039531", "l": "regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003051", "l": "angiotensin-mediated drinking behavior", "d": ["The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110094", "l": "polyphosphate-mediated signaling", "d": ["Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:1900428", "l": "regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160035", "l": "negative regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Toll receptor ligand protein activation cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060704", "l": "acinar cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043490", "l": "malate-aspartate shuttle", "d": ["The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903237", "l": "negative regulation of leukocyte tethering or rolling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140604", "l": "mycofactocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106218", "l": "galactosaminogalactan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071688", "l": "striated muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051454", "l": "intracellular pH elevation", "d": ["Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036448", "l": "cellular response to glucose-phosphate stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060944", "l": "neural crest-derived cardiac fibroblast cell fate commitment", "d": ["The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000902", "l": "cellooligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving a cellooligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0120168", "l": "detection of hot stimulus involved in thermoception", "d": ["The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060566", "l": "positive regulation of termination of DNA-templated transcription", "d": ["Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035751", "l": "regulation of lysosomal lumen pH", "d": ["Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003106", "l": "negative regulation of glomerular filtration by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903846", "l": "positive regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901519", "l": "aspyridone B metabolic process", "d": ["The chemical reactions and pathways involving aspyridone B."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900091", "l": "regulation of raffinose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of raffinose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007413", "l": "axonal fasciculation", "d": ["The collection of axons into a bundle of rods, known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032909", "l": "regulation of transforming growth factor beta2 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019257", "l": "4-nitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900754", "l": "4-hydroxyphenylacetate transport", "d": ["The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900682", "l": "octadecene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octadecene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990933", "l": "microtubule cytoskeleton attachment to nuclear envelope", "d": ["A process in which the microtubule cytoskeleton is attached to the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021637", "l": "trigeminal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006636", "l": "unsaturated fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060287", "l": "epithelial cilium movement involved in determination of left/right asymmetry", "d": ["The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043653", "l": "mitochondrial fragmentation involved in apoptotic process", "d": ["The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019476", "l": "D-lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.546003967123667", "identifiers": [{"i": "GO:0006357", "l": "regulation of transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.391713369466018", "identifiers": [{"i": "GO:0046883", "l": "regulation of hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0019054", "l": "modulation by virus of host cellular process", "d": ["The process in which a virus effects a change in the processes and activities of its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003118", "l": "regulation of vasoconstriction by neuronal norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071783", "l": "endoplasmic reticulum cisternal network organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902276", "l": "regulation of pancreatic amylase secretion", "d": ["Any process that modulates the frequency, rate or extent of pancreatic amylase secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110042", "l": "negative regulation of pharynx morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033623", "l": "regulation of integrin activation", "d": ["Any process that modulates the frequency, rate, or extent of integrin activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006856", "l": "eye pigment precursor transport", "d": ["The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046079", "l": "dUMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072752", "l": "cellular response to rapamycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010039", "l": "response to iron ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032256", "l": "establishment of dense core granule localization", "d": ["The directed movement of a dense core granule to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903125", "l": "negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation", "d": ["A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048336", "l": "positive regulation of mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903910", "l": "negative regulation of receptor clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900686", "l": "regulation of gerfelin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904927", "l": "cellular response to palmitoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000359", "l": "regulation of binding of sperm to zona pellucida", "d": ["Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905488", "l": "positive regulation of anterior/posterior axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072275", "l": "metanephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the metanephric glomerulus are generated and organized. 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They are specialized epithelial cells that are organized into interconnected plates called lobules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009399", "l": "nitrogen fixation", "d": ["The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:1903050", "l": "regulation of proteolysis involved in protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990671", "l": "vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903947", "l": "positive regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071607", "l": "macrophage inflammatory protein-1 gamma production", "d": ["The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901810", "l": "beta-carotene metabolic process", "d": ["The chemical reactions and pathways involving beta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904202", "l": "negative regulation of iodide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010088", "l": "phloem development", "d": ["The formation of the principal food-conducting tissue of a vascular plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043307", "l": "eosinophil activation", "d": ["The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062162", "l": "positive regulation of pyocyanine biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072095", "l": "regulation of branch elongation involved in ureteric bud branching", "d": ["Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007527", "l": "adult somatic muscle development", "d": ["The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900347", "l": "positive regulation of methane biosynthetic process from methanethiol", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046292", "l": "formaldehyde metabolic process", "d": ["The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0141041", "l": "disruption of extracellular matrix of another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the breakdown of the extracellular matrix of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036520", "l": "astrocyte-dopaminergic neuron signaling", "d": ["Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060006", "l": "angular vestibuloocular reflex", "d": ["A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061740", "l": "protein targeting to lysosome involved in chaperone-mediated autophagy", "d": ["The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0090150", "l": "establishment of protein localization to membrane", "d": ["The directed movement of a protein to a specific location in a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006009", "l": "glucose 1-phosphate phosphorylation", "d": ["The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904232", "l": "regulation of aconitate hydratase activity", "d": ["Any process that modulates the frequency, rate or extent of aconitate hydratase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034721", "l": "histone H3-K4 demethylation, trimethyl-H3-K4-specific", "d": ["The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990799", "l": "mitochondrial tRNA wobble position uridine thiolation", "d": ["The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:1905037", "l": "autophagosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045488", "l": "pectin metabolic process", "d": ["The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905410", "l": "regulation of mitotic cohesin unloading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin unloading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000623", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010288", "l": "response to lead ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042637", "l": "catagen", "d": ["The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097302", "l": "lipoprotein biosynthetic process via diacylglyceryl transfer", "d": ["The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032231", "l": "regulation of actin filament bundle assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043691", "l": "reverse cholesterol transport", "d": ["The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044809", "l": "chemokine (C-C motif) ligand 17 production", "d": ["The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016095", "l": "polyprenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903371", "l": "regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039700", "l": "fusion of viral membrane with host outer nuclear membrane", "d": ["Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. 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Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903658", "l": "positive regulation of type IV pilus biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036242", "l": "glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016201", "l": "synaptic target inhibition", "d": ["The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046458", "l": "hexadecanal metabolic process", "d": ["The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070147", "l": "mitochondrial cysteinyl-tRNA aminoacylation", "d": ["The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048615", "l": "embryonic anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097366", "l": "response to bronchodilator", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046064", "l": "dCMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062032", "l": "cichorine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045815", "l": "transcription initiation-coupled chromatin remodeling", "d": ["An epigenetic mechanism of regulation of gene expression that involves chromatin remodeling to capacitate gene expression by either modifying the chromatin fiber, the nucleosomal histones, or the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.8317879456661", "identifiers": [{"i": "GO:0030097", "l": "hemopoiesis", "d": ["The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904572", "l": "negative regulation of mRNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046362", "l": "ribitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905672", "l": "negative regulation of lysosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052472", "l": "modulation by host of symbiont transcription", "d": ["Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110059", "l": "negative regulation of blood vessel endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902796", "l": "regulation of snoRNA processing", "d": ["Any process that modulates the frequency, rate or extent of snoRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044493", "l": "envenomation resulting in negative regulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035364", "l": "thymine transport", "d": ["The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032643", "l": "regulation of connective tissue growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of connective tissue growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099614", "l": "protein localization to spore cell wall", "d": ["A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010917", "l": "negative regulation of mitochondrial membrane potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904128", "l": "negative regulation of convergent extension involved in somitogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016130", "l": "phytosteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071456", "l": "cellular response to hypoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060312", "l": "regulation of blood vessel remodeling", "d": ["Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048107", "l": "4-amino-3-isothiazolidinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1903338", "l": "regulation of cell wall organization or biogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046380", "l": "N-acetylneuraminate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990314", "l": "cellular response to insulin-like growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900861", "l": "regulation of cordyol C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009178", "l": "pyrimidine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051395", "l": "negative regulation of nerve growth factor receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904562", "l": "phosphatidylinositol 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylinositol 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0003338", "l": "metanephros morphogenesis", "d": ["The process in which the anatomical structures of the metanephros are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0009415", "l": "response to water", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006146", "l": "adenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0001840", "l": "neural plate development", "d": ["The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0072666", "l": "establishment of protein localization to vacuole", "d": ["The directed movement of a protein to a specific location in a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.481265292451688", "identifiers": [{"i": "GO:0005996", "l": "monosaccharide metabolic process", "d": ["The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071785", "l": "endoplasmic reticulum cisternal network maintenance", "d": ["The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098785", "l": "biofilm matrix assembly", "d": ["A process that results in the assembly of a biofilm matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0010559", "l": "regulation of glycoprotein biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034626", "l": "fatty acid elongation, polyunsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:2000377", "l": "regulation of reactive oxygen species metabolic process", "d": ["Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110034", "l": "negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010992", "l": "ubiquitin recycling", "d": ["Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001866", "l": "NK T cell proliferation", "d": ["The expansion of a NK T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060172", "l": "astral microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034289", "l": "detection of maltose stimulus", "d": ["The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990036", "l": "calcium ion import into sarcoplasmic reticulum", "d": ["The directed movement of calcium ions into a sarcoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.25425787406018", "identifiers": [{"i": "GO:0050776", "l": "regulation of immune response", "d": ["Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080064", "l": "4,4-dimethyl-9beta,19-cyclopropylsterol oxidation", "d": ["A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021978", "l": "telencephalon regionalization", "d": ["The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0051957", "l": "positive regulation of amino acid transport", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097036", "l": "regulation of plasma membrane sterol distribution", "d": ["Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903769", "l": "negative regulation of cell proliferation in bone marrow", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901902", "l": "tyrocidine metabolic process", "d": ["The chemical reactions and pathways involving tyrocidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016340", "l": "calcium-dependent cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032257", "l": "maintenance of dense core granule location", "d": ["Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0061206", "l": "mesonephros morphogenesis", "d": ["The process in which the anatomical structures of the mesonephros are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903909", "l": "regulation of receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0086027", "l": "AV node cell to bundle of His cell signaling", "d": ["Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070804", "l": "positive regulation of metula development", "d": ["Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016199", "l": "axon midline choice point recognition", "d": ["The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060739", "l": "mesenchymal-epithelial cell signaling involved in prostate gland development", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019455", "l": "L-cysteine catabolic process via cystine, using cystine reductase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0006506", "l": "GPI anchor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1904498", "l": "protein localization to mitotic actomyosin contractile ring", "d": ["Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.777771579090697", "identifiers": [{"i": "GO:0048514", "l": "blood vessel morphogenesis", "d": ["The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904246", "l": "negative regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019398", "l": "gallate catabolic process via gallate dioxygenase activity", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010492", "l": "maintenance of shoot apical meristem identity", "d": ["The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022614", "l": "membrane to membrane docking", "d": ["The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0003206", "l": "cardiac chamber morphogenesis", "d": ["The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043465", "l": "regulation of fermentation", "d": ["Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901459", "l": "positive regulation of response to acetate", "d": ["Any process that activates or increases the frequency, rate or extent of response to acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072253", "l": "metanephric juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106210", "l": "culmorin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903403", "l": "negative regulation of renal phosphate excretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071353", "l": "cellular response to interleukin-4", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014895", "l": "smooth muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034034", "l": "purine nucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.957607393616669", "identifiers": [{"i": "GO:0051049", "l": "regulation of transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036215", "l": "response to stem cell factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1990009", "l": "retinal cell apoptotic process", "d": ["Any apoptotic process in a retinal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070502", "l": "capsule poly-gamma-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034223", "l": "regulation of ascospore wall chitin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002266", "l": "follicular dendritic cell activation", "d": ["A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071656", "l": "negative regulation of granulocyte colony-stimulating factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070194", "l": "synaptonemal complex disassembly", "d": ["The controlled breakdown of a synaptonemal complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900746", "l": "regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0043271", "l": "negative regulation of monoatomic ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900658", "l": "regulation of emericellamide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008069", "l": "dorsal/ventral axis specification, ovarian follicular epithelium", "d": ["Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006294", "l": "nucleotide-excision repair, preincision complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039502", "l": "suppression by virus of host type I interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072093", "l": "metanephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000024", "l": "maltose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990637", "l": "response to prolactin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043556", "l": "regulation of translation in response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060721", "l": "regulation of spongiotrophoblast cell proliferation", "d": ["Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900766", "l": "emericellin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019687", "l": "pyruvate biosynthetic process from acetate", "d": ["The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030839", "l": "regulation of intermediate filament polymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070496", "l": "positive regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010483", "l": "pollen tube reception", "d": ["Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061384", "l": "heart trabecula morphogenesis", "d": ["The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033534", "l": "verbascose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001206", "l": "positive regulation of osteoclast development", "d": ["Any process that activates or increases the frequency, rate or extent of osteoclast development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030642", "l": "intracellular sulfate ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1902001", "l": "fatty acid transmembrane transport", "d": ["The process in which a fatty acid is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019746", "l": "hopanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007027", "l": "negative regulation of axonemal microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.35485747081789", "identifiers": [{"i": "GO:0051649", "l": "establishment of localization in cell", "d": ["Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034120", "l": "positive regulation of erythrocyte aggregation", "d": ["Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018880", "l": "4-chlorobiphenyl metabolic process", "d": ["The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900697", "l": "positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001839", "l": "neural plate morphogenesis", "d": ["The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902733", "l": "regulation of growth plate cartilage chondrocyte differentiation", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0001907", "l": "killing by symbiont of host cells", "d": ["Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0006023", "l": "aminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019500", "l": "cyanide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032964", "l": "collagen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.483855464319362", "identifiers": [{"i": "GO:0048477", "l": "oogenesis", "d": ["The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010691", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0007031", "l": "peroxisome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905460", "l": "negative regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0035372", "l": "protein localization to microtubule", "d": ["A process in which a protein is transported to, or maintained at, a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048698", "l": "negative regulation of collateral sprouting in absence of injury", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009943", "l": "adaxial/abaxial axis specification", "d": ["The establishment, maintenance and elaboration of the adaxial / abaxial axis. 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Protein maturation is included when required to form an active form of a product from an inactive precursor form."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0043457", "l": "regulation of cellular respiration", "d": ["Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034965", "l": "intronic box C/D RNA processing", "d": ["Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045490", "l": "pectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060063", "l": "Spemann organizer formation at the embryonic shield", "d": ["Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110091", "l": "negative regulation of hippocampal neuron apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072276", "l": "metanephric glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002038", "l": "positive regulation of L-glutamate import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080026", "l": "response to indolebutyric acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990654", "l": "sebum secreting cell proliferation", "d": ["The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. 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A neuron projection is any process extending from a neural cell, such as axons or dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010457", "l": "centriole-centriole cohesion", "d": ["The cell cycle process in which the two centrioles within a centrosome remain tightly paired."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044490", "l": "positive regulation of voltage-gated sodium channel activity in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000407", "l": "regulation of T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140723", "l": "patulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006077", "l": "(1->6)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902214", "l": "regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010879", "l": "cholesterol transport involved in cholesterol storage", "d": ["The directed movement of cholesterol into cells that is part of their accumulation and maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.401739174461731", "identifiers": [{"i": "GO:0033554", "l": "cellular response to stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000389", "l": "regulation of neutrophil extravasation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0033598", "l": "mammary gland epithelial cell proliferation", "d": ["The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0032950", "l": "regulation of beta-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045326", "l": "protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007356", "l": "thorax and anterior abdomen determination", "d": ["Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.670000558372379", "identifiers": [{"i": "GO:0031175", "l": "neuron projection development", "d": ["The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0032886", "l": "regulation of microtubule-based process", "d": ["Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046193", "l": "anaerobic phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0022608", "l": "multicellular organism adhesion", "d": ["The attachment of a multicellular organism to a substrate 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"GO:0051102", "l": "DNA ligation involved in DNA recombination", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098932", "l": "disruption by virus of host cell wall peptidoglycan during virus entry", "d": ["A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010685", "l": "tetracyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098658", "l": "inorganic anion import across plasma membrane", "d": ["The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905270", "l": "Meynert cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099645", "l": "neurotransmitter receptor localization to postsynaptic specialization membrane", "d": ["A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000642", "l": "negative regulation of early endosome to late endosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome 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"d": ["The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052325", "l": "cell wall pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034313", "l": "diol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060800", "l": "regulation of cell differentiation involved in embryonic placenta development", "d": ["Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006034", "l": "cuticle chitin metabolic process", "d": ["The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900138", "l": "negative regulation of phospholipase A2 activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071636", "l": "positive regulation of transforming growth factor beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045837", "l": "negative regulation of membrane potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035945", "l": "mitochondrial ncRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046152", "l": "ommochrome metabolic process", "d": ["The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055047", "l": "generative cell mitosis", "d": ["The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0052562", "l": "suppression by symbiont of host immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000766", "l": "negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation", "d": ["In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072029", "l": "long nephron development", "d": ["The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002615", "l": "positive regulation of monocyte antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045213", "l": "neurotransmitter receptor metabolic process", "d": ["The chemical reactions and pathways involving neurotransmitter receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090445", "l": "positive regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006529", "l": "asparagine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052643", "l": "chlorophyllide metabolic process", "d": ["The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.096636849693901", "identifiers": [{"i": "GO:0048872", "l": "homeostasis of number of cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046544", "l": "development of secondary male sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901183", "l": "positive regulation of camalexin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070339", "l": "response to bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001842", "l": "neural fold formation", "d": ["The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070344", "l": "regulation of fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021609", "l": "accessory nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021917", "l": "somatic motor neuron fate commitment", "d": ["The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035688", "l": "T-helper 1 cell diapedesis", "d": ["The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032194", "l": "ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045973", "l": "positive regulation of juvenile hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003121", "l": "epinephrine-mediated vasodilation", "d": ["A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045966", "l": "positive regulation of ecdysteroid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075257", "l": "positive regulation of teliospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902779", "l": "cellular response to alkane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060243", "l": "negative regulation of cell growth involved in contact inhibition", "d": ["The negative regulation of cell growth in response to increased cell density."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045214", "l": "sarcomere organization", "d": ["The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032308", "l": "positive regulation of prostaglandin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097241", "l": "hematopoietic stem cell migration to bone marrow", "d": ["The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0070198", "l": "protein localization to chromosome, telomeric region", "d": ["Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060769", "l": "positive regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903139", "l": "positive regulation of cell wall integrity MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097395", "l": "response to interleukin-32", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034473", "l": "U1 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U1 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0048333", "l": "mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030650", "l": "peptide antibiotic metabolic process", "d": ["The chemical reactions and pathways involving peptides with antibiotic activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903286", "l": "regulation of potassium ion import", "d": ["Any process that modulates the frequency, rate or extent of potassium ion import."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061272", "l": "mesonephric connecting tubule development", "d": ["The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010250", "l": "S-methylmethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019441", "l": "tryptophan catabolic process to kynurenine", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014878", "l": "response to electrical stimulus involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.196521192641157", "identifiers": [{"i": "GO:0060361", "l": "flight", "d": ["Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043099", "l": "pyrimidine deoxyribonucleoside salvage", "d": ["Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0030203", "l": "glycosaminoglycan metabolic process", "d": ["The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902934", "l": "isopentenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010342", "l": "endosperm cellularization", "d": ["The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006860", "l": "extracellular amino acid transport", "d": ["The directed extracellular movement of amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990390", "l": "protein K33-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1990896", "l": "protein localization to cell cortex of cell tip", "d": ["A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002518", "l": "lymphocyte chemotaxis across high endothelial venule", "d": ["The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036068", "l": "light-independent chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010380", "l": "regulation of chlorophyll biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904403", "l": "cellular response to nocodazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051134", "l": "negative regulation of NK T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905279", "l": "regulation of retrograde transport, endosome to Golgi", "d": ["Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007087", "l": "mitotic nuclear pore complex reassembly", "d": ["The cell cycle process in which nuclear pore complexes reform during mitotic cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.885542599809028", "identifiers": [{"i": "GO:0003018", "l": "vascular process in circulatory system", "d": ["A circulatory process that occurs at the level of the vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050949", "l": "negative regulation of late stripe melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071454", "l": "cellular response to anoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034089", "l": "establishment of meiotic sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:1903829", "l": "positive regulation of protein localization", "d": ["Any process that activates or increases the frequency, rate or extent of a protein localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014022", "l": "neural plate elongation", "d": ["The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061433", "l": "cellular response to caloric restriction", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031393", "l": "negative regulation of prostaglandin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000849", "l": "regulation of glucocorticoid secretion", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042791", "l": "5S class rRNA transcription by RNA polymerase III", "d": ["The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075190", "l": "negative regulation of hyphopodium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000096", "l": "positive regulation of Wnt signaling pathway, planar cell polarity pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:2000401", "l": "regulation of lymphocyte migration", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048317", "l": "seed morphogenesis", "d": ["The process in which the anatomical structures of the seed are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048662", "l": "negative regulation of smooth muscle cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.969489883774216", "identifiers": [{"i": "GO:0034504", "l": "protein localization to nucleus", "d": ["A process in which a protein transports or maintains the localization of another protein to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0140499", "l": "negative regulation of mitotic spindle assembly checkpoint signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990086", "l": "lens fiber cell apoptotic process", "d": ["Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003146", "l": "heart jogging", "d": ["The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097688", "l": "glutamate receptor clustering", "d": ["The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033146", "l": "regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010880", "l": "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "d": ["Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032686", "l": "negative regulation of hepatocyte growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036162", "l": "oxytocin production", "d": ["The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051792", "l": "medium-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900109", "l": "regulation of histone H3-K9 dimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000547", "l": "regulation of dendritic cell dendrite assembly", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018278", "l": "N-terminal peptidyl-threonine deamination", "d": ["The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003020", "l": "detection of reduced oxygen by chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006248", "l": "CMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060513", "l": "prostatic bud formation", "d": ["The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.803933740867301", "identifiers": [{"i": "GO:0016570", "l": "histone modification", "d": ["The covalent alteration of one or more amino acid residues within a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.367368887635308", "identifiers": [{"i": "GO:0071496", "l": "cellular response to external stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042004", "l": "feminization of hermaphrodite soma", "d": ["Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904685", "l": "positive regulation of metalloendopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019384", "l": "caprolactam catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900726", "l": "osmoregulated periplasmic glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0009799", "l": "specification of symmetry", "d": ["The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071984", "l": "maintenance of reproductive diapause", "d": ["The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048088", "l": "regulation of male pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900975", "l": "negative regulation of tatiopterin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060432", "l": "lung pattern specification process", "d": ["Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044556", "l": "envenomation resulting in negative regulation of heart rate in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031629", "l": "synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901845", "l": "negative regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048899", "l": "anterior lateral line development", "d": ["The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061565", "l": "dAMP phosphorylation", "d": ["The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046392", "l": "galactarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015751", "l": "arabinose transmembrane transport", "d": ["The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902731", "l": "negative regulation of chondrocyte proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106398", "l": "negative regulation of R7 cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000412", "l": "positive regulation of thymocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039702", "l": "viral budding via host ESCRT complex", "d": ["Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990828", "l": "hepatocyte dedifferentiation", "d": ["The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0007142", "l": "male meiosis II", "d": ["A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018274", "l": "peptide cross-linking via L-lysinoalanine", "d": ["The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021935", "l": "cerebellar granule cell precursor tangential migration", "d": ["The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048074", "l": "negative regulation of eye pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120247", "l": "acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010067", "l": "procambium histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000892", "l": "cellobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellobiose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021588", "l": "cerebellum formation", "d": ["The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034396", "l": "negative regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048908", "l": "anterior lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002927", "l": "archaeosine-tRNA biosynthetic process", "d": ["The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060846", "l": "blood vessel endothelial cell fate commitment", "d": ["The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046792", "l": "suppression by virus of host cell cycle arrest", "d": ["Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010533", "l": "regulation of activation of Janus kinase activity", "d": ["Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:1902644", "l": "tertiary alcohol metabolic process", "d": ["The chemical reactions and pathways involving tertiary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070544", "l": "histone H3-K36 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051694", "l": "pointed-end actin filament capping", "d": ["The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0006591", "l": "ornithine metabolic process", "d": ["The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032610", "l": "interleukin-1 alpha production", "d": ["The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009780", "l": "photosynthetic NADP+ reduction", "d": ["An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010075", "l": "regulation of meristem growth", "d": ["Any process involved in maintaining the size and shape of a meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904462", "l": "ergosteryl 3-beta-D-glucoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021752", "l": "inferior salivary nucleus development", "d": ["The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001199", "l": "negative regulation of dendritic cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033079", "l": "immature T cell proliferation", "d": ["The expansion of an immature T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0098743", "l": "cell aggregation", "d": ["The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098729", "l": "germline stem cell symmetric division", "d": ["Division of a germline stem cell to produce two germline stem cells of the same type as the parent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044844", "l": "meiotic interphase II", "d": ["The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033074", "l": "pinene catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032214", "l": "negative regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006063", "l": "uronic acid metabolic process", "d": ["The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021851", "l": "neuroblast division in dorsal lateral ganglionic eminence", "d": ["The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0048857", "l": "neural nucleus development", "d": ["The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001955", "l": "blood vessel maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0003071", "l": "renal system process involved in regulation of systemic arterial blood pressure", "d": ["Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043929", "l": "primary ovarian follicle growth involved in double layer follicle stage", "d": ["Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035698", "l": "CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0098516", "l": "detection of high humidity", "d": ["The series of events in which high humidity is detected and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901130", "l": "gentamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gentamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019270", "l": "aerobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090105", "l": "pancreatic E cell development", "d": ["The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902091", "l": "negative regulation of fumagillin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001168", "l": "positive regulation of histone H2B ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071368", "l": "cellular response to cytokinin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018362", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030245", "l": "cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.138589647363986", "identifiers": [{"i": "GO:0050912", "l": "detection of chemical stimulus involved in sensory perception of taste", "d": ["The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990575", "l": "mitochondrial L-ornithine transmembrane transport", "d": ["The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0005985", "l": "sucrose metabolic process", "d": ["The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060668", "l": "regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.737964419941491", "identifiers": [{"i": "GO:0019226", "l": "transmission of nerve impulse", "d": ["The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046671", "l": "negative regulation of retinal cell programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036353", "l": "histone H2A-K119 monoubiquitination", "d": ["The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.640334783545086", "identifiers": [{"i": "GO:0061061", "l": "muscle structure development", "d": ["The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042457", "l": "ethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0036388", "l": "pre-replicative complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002782", "l": "antifungal peptide secretion", "d": ["The regulated release of an antifungal peptide from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110037", "l": "regulation of nematode male tail tip morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071386", "l": "cellular response to corticosterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051758", "l": "homologous chromosome movement towards spindle pole in meiosis I anaphase", "d": ["The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.100229552557821", "identifiers": [{"i": "GO:0000226", "l": "microtubule cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016059", "l": "deactivation of rhodopsin mediated signaling", "d": ["The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046337", "l": "phosphatidylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045041", "l": "protein import into mitochondrial intermembrane space", "d": ["The import of proteins into the space between the inner and outer mitochondrial membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010127", "l": "mycothiol-dependent detoxification", "d": ["The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901442", "l": "regulation of response to furfural", "d": ["Any process that modulates the frequency, rate or extent of response to furfural."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061146", "l": "Peyer's patch morphogenesis", "d": ["The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000466", "l": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051473", "l": "glucosylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020035", "l": "adhesion of symbiont to microvasculature", "d": ["The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060299", "l": "negative regulation of sarcomere organization", "d": ["Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048108", "l": "peptide cross-linking via 4-amino-3-isothiazolidinone", "d": ["The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902767", "l": "isoprenoid biosynthetic process via mevalonate", "d": ["The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019401", "l": "alditol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019605", "l": "butyrate metabolic process", "d": ["The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071635", "l": "negative regulation of transforming growth factor beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990892", "l": "mitotic chromosome arm condensation", "d": ["The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120322", "l": "lipid modification by small protein conjugation", "d": ["A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051031", "l": "tRNA transport", "d": ["The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033546", "l": "myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate", "d": ["The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000716", "l": "transcription-coupled nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070681", "l": "glutaminyl-tRNAGln biosynthesis via transamidation", "d": ["A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042193", "l": "methylmercury catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.306098259633643", "identifiers": [{"i": "GO:0060349", "l": "bone morphogenesis", "d": ["The process in which bones are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0006418", "l": "tRNA aminoacylation for protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052130", "l": "negative aerotaxis", "d": ["The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046529", "l": "imaginal disc fusion, thorax closure", "d": ["The joining of the parts of the wing imaginal discs, giving rise to the adult thorax."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010567", "l": "regulation of ketone catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106013", "l": "negative regulation of protein localization to cell cortex of cell tip", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1901019", "l": "regulation of calcium ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0045814", "l": "negative regulation of gene expression, epigenetic", "d": ["An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903559", "l": "3-cyano-L-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046726", "l": "positive regulation by virus of viral protein levels in host cell", "d": ["Any process where the infecting virus increases the levels of viral proteins in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0007616", "l": "long-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002670", "l": "regulation of B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043117", "l": "positive regulation of vascular permeability", "d": ["Any process that increases the extent to which blood vessels can be pervaded by fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048566", "l": "embryonic digestive tract development", "d": ["The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0070201", "l": "regulation of establishment of protein localization", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0050708", "l": "regulation of protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.981760983962317", "identifiers": [{"i": "GO:0019222", "l": "regulation of metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000387", "l": "regulation of antral ovarian follicle growth", "d": ["Any process that modulates the frequency, rate or extent of antral ovarian follicle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043096", "l": "purine nucleobase salvage", "d": ["Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007502", "l": "digestive tract mesoderm development", "d": ["The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043433", "l": "negative regulation of DNA-binding transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905686", "l": "positive regulation of plasma membrane repair", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048540", "l": "bursa of Fabricius development", "d": ["The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072034", "l": "renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009243", "l": "O antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042759", "l": "long-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0042093", "l": "T-helper cell differentiation", "d": ["The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904474", "l": "cellular response to L-dopa", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0018200", "l": "peptidyl-glutamic acid modification", "d": ["The modification of peptidyl-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0010015", "l": "root morphogenesis", "d": ["The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140730", "l": "amphiregulin production", "d": ["The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071919", "l": "G-quadruplex DNA formation", "d": ["A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0051283", "l": "negative regulation of sequestering of calcium ion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045691", "l": "regulation of embryo sac central cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0016110", "l": "tetraterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904150", "l": "negative regulation of microglial cell mediated cytotoxicity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072264", "l": "metanephric glomerular endothelium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045842", "l": "positive regulation of mitotic metaphase/anaphase transition", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090616", "l": "mitochondrial mRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900519", "l": "negative regulation of response to pullulan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905002", "l": "positive regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099585", "l": "release of sequestered calcium ion into presynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021859", "l": "pyramidal neuron differentiation", "d": ["The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0002387", "l": "immune response in gut-associated lymphoid tissue", "d": ["Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000471", "l": "endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903193", "l": "sesquarterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquarterpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902069", "l": "negative regulation of sphingolipid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006601", "l": "creatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032468", "l": "Golgi calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002467", "l": "germinal center formation", "d": ["The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990550", "l": "mitochondrial alpha-ketoglutarate transmembrane transport", "d": ["The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015939", "l": "pantothenate metabolic process", "d": ["The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904293", "l": "negative regulation of ERAD pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0030335", "l": "positive regulation of cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150062", "l": "complement-mediated synapse pruning", "d": ["Synaptic pruning mediated by complement system signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072186", "l": "metanephric cap morphogenesis", "d": ["The process in which the anatomical structures of the metanephric cap are generated and organized. 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Long-chain fatty-acyl-CoAs have chain lengths of C13 or more."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001966", "l": "thigmotaxis", "d": ["The directed movement of an animal in response to touch."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015728", "l": "mevalonate transport", "d": ["The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006713", "l": "glucocorticoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0002777", "l": "antimicrobial peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901357", "l": "beta-D-galactofuranose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031144", "l": "proteasome localization", "d": ["Any process in which the proteasome is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106217", "l": "tRNA C3-cytosine methylation", "d": ["The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905264", "l": "blasticidin S metabolic process", "d": ["The chemical reactions and pathways involving blasticidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901904", "l": "tyrocidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyrocidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902668", "l": "negative regulation of axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0042303", "l": "molting cycle", "d": ["The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900016", "l": "negative regulation of cytokine production involved in inflammatory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.561493752554874", "identifiers": [{"i": "GO:0031667", "l": "response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039675", "l": "exit of virus from host cell nucleus through nuclear pore", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904830", "l": "negative regulation of aortic smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048885", "l": "neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070796", "l": "regulation of cleistothecium development", "d": ["Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035119", "l": "embryonic pelvic fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.959548363731535", "identifiers": [{"i": "GO:0007417", "l": "central nervous system development", "d": ["The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060121", "l": "vestibular receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0001710", "l": "mesodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the mesoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905648", "l": "regulation of shell calcification", "d": ["Any process that modulates the frequency, rate or extent of shell calcification."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0046470", "l": "phosphatidylcholine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033522", "l": "histone H2A ubiquitination", "d": ["The modification of histone H2A by addition of one or more ubiquitin groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061297", "l": "positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0019362", "l": "pyridine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0036166", "l": "phenotypic switching", "d": ["A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. 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Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0016226", "l": "iron-sulfur cluster assembly", "d": ["The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150159", "l": "negative regulation of interleukin-34 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061818", "l": "tRNA folding", "d": ["The process of assisting in the folding of tRNAs into the correct tertiary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046596", "l": "regulation of viral entry into host cell", "d": ["Any process that modulates the frequency, rate or extent of the viral entry into the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140766", "l": "siRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990535", "l": "neuron projection maintenance", "d": ["The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006203", "l": "dGTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034151", "l": "regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.629028984204552", "identifiers": [{"i": "GO:0006721", "l": "terpenoid metabolic process", "d": ["The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006797", "l": "polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001999", "l": "renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure", "d": ["The physiological response of the kidneys to a decrease in blood flow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043151", "l": "DNA synthesis involved in double-strand break repair via single-strand annealing", "d": ["The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090678", "l": "cell dedifferentiation involved in phenotypic switching", "d": ["A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039688", "l": "viral double stranded DNA replication via reverse transcription", "d": ["A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0021983", "l": "pituitary gland development", "d": ["The progression of the pituitary gland over time from its initial formation until its mature state. 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Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.969909400061496", "identifiers": [{"i": "GO:0072006", "l": "nephron development", "d": ["The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. 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Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097341", "l": "zymogen inhibition", "d": ["Any process that prevents the proteolytic processing of an inactive enzyme to an active form."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120055", "l": "small intestinal transit", "d": ["Migration of ingested material along the length of the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900144", "l": "positive regulation of BMP secretion", "d": ["Any process that activates or increases the frequency, rate or extent of BMP secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062126", "l": "fatty acid primary amide metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044519", "l": "envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090389", "l": "phagosome-lysosome fusion involved in apoptotic cell clearance", "d": ["The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070862", "l": "negative regulation of protein exit from endoplasmic reticulum", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905542", "l": "negative regulation of L-arginine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035919", "l": "negative regulation of low voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900955", "l": "positive regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903715", "l": "regulation of aerobic respiration", "d": ["Any process that modulates the frequency, rate or extent of aerobic respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900942", "l": "negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000748", "l": "positive regulation of defecation rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of defecation rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018358", "l": "protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine", "d": ["The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007400", "l": "neuroblast fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002324", "l": "natural killer cell proliferation involved in immune response", "d": ["The expansion of a natural killer cell population by cell division as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098866", "l": "multivesicular body fusion to apical plasma membrane", "d": ["The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901560", "l": "response to purvalanol A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0006775", "l": "fat-soluble vitamin metabolic process", "d": ["The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905161", "l": "protein localization to phagocytic vesicle", "d": ["A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0036336", "l": "dendritic cell migration", "d": ["The movement of a dendritic cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051151", "l": "negative regulation of smooth muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030241", "l": "skeletal muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019568", "l": "arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902114", "l": "D-valine metabolic process", "d": ["The chemical reactions and pathways involving D-valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052128", "l": "positive energy taxis", "d": ["The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061808", "l": "negative regulation of DNA recombination at centromere", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062209", "l": "spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043182", "l": "vacuolar sequestering of sodium ion", "d": ["The process of transporting sodium ions into, and confining within, a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033243", "l": "positive regulation of amine catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905117", "l": "regulation of ribonucleoside-diphosphate reductase activity", "d": ["Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990134", "l": "epithelial cell apoptotic process involved in palatal shelf morphogenesis", "d": ["An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030300", "l": "regulation of intestinal cholesterol absorption", "d": ["Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0001956", "l": "positive regulation of neurotransmitter secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0001890", "l": "placenta development", "d": ["The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035156", "l": "fusion cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052084", "l": "modulation by symbiont of host ethylene-mediated defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140435", "l": "negative regulation of protein localization to meiotic spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001921", "l": "positive regulation of receptor recycling", "d": ["Any process that activates or increases the frequency, rate or extent of receptor recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019420", "l": "dissimilatory sulfate reduction", "d": ["The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043335", "l": "protein unfolding", "d": ["The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070608", "l": "regulation of cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006360", "l": "transcription by RNA polymerase I", "d": ["The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0021987", "l": "cerebral cortex development", "d": ["The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902660", "l": "negative regulation of glucose mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905365", "l": "regulation of intralumenal vesicle formation", "d": ["Any process that modulates the frequency, rate or extent of intralumenal vesicle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090116", "l": "C-5 methylation of cytosine", "d": ["The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140505", "l": "regulation of microlipophagy", "d": ["Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060213", "l": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032611", "l": "interleukin-1 beta production", "d": ["The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.381710255175513", "identifiers": [{"i": "GO:0034762", "l": "regulation of transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035777", "l": "pronephric distal tubule development", "d": ["The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0120305", "l": "regulation of pigmentation", "d": ["Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007121", "l": "bipolar cellular bud site selection", "d": ["The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035136", "l": "forelimb morphogenesis", "d": ["The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044405", "l": "detection of host", "d": ["The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043366", "l": "beta selection", "d": ["The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0001942", "l": "hair follicle development", "d": ["The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018928", "l": "methyl ethyl ketone metabolic process", "d": ["The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990569", "l": "UDP-N-acetylglucosamine transmembrane transport", "d": ["The process in which UDP-N-acetylglucosamine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007407", "l": "neuroblast activation", "d": ["A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006071", "l": "glycerol metabolic process", "d": ["The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001975", "l": "response to amphetamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045626", "l": "negative regulation of T-helper 1 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000187", "l": "positive regulation of phosphate transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905034", "l": "regulation of antifungal innate immune response", "d": ["Any process that modulates the frequency, rate or extent of an antifungal innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0120032", "l": "regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098597", "l": "observational learning", "d": ["Learning that occurs through observing the behavior of others."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0042157", "l": "lipoprotein metabolic process", "d": ["The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990516", "l": "ribonucleotide excision repair", "d": ["The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030500", "l": "regulation of bone mineralization", "d": ["Any process that modulates the frequency, rate or extent of bone mineralization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032746", "l": "positive regulation of interleukin-22 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-22 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140216", "l": "negative regulation of D-aspartate import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097389", "l": "chemokine (C-C motif) ligand 21 production", "d": ["The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000998", "l": "negative regulation of cellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000949", "l": "negative regulation of xyloglucan metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009079", "l": "pyruvate family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902561", "l": "origin recognition complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902354", "l": "blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment", "d": ["Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060192", "l": "negative regulation of lipase activity", "d": ["Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043013", "l": "negative regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000822", "l": "regulation of behavioral fear response", "d": ["Any process that modulates the frequency, rate or extent of behavioral fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902962", "l": "regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032330", "l": "regulation of chondrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of chondrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060421", "l": "positive regulation of heart growth", "d": ["Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902307", "l": "positive regulation of sodium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072535", "l": "tumor necrosis factor (ligand) superfamily member 11 production", "d": ["The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072682", "l": "eosinophil extravasation", "d": ["The migration of an eosinophil from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033248", "l": "negative regulation of penicillin catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009762", "l": "NADP-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009602", "l": "detection of symbiont", "d": ["The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039684", "l": "rolling circle single-stranded viral DNA replication", "d": ["A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044641", "l": "envenomation resulting in positive regulation of complement activation, lectin pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904279", "l": "regulation of transcription by RNA polymerase V", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061907", "l": "negative regulation of AMPA receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003289", "l": "atrial septum primum morphogenesis", "d": ["The process in which anatomical structure of an atrial septum primum is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006864", "l": "pyrimidine nucleotide transport", "d": ["The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904078", "l": "positive regulation of estrogen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097331", "l": "response to cytarabine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900715", "l": "positive regulation of violaceol I biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021603", "l": "cranial nerve formation", "d": ["The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033515", "l": "L-lysine catabolic process using lysine 6-aminotransferase", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001172", "l": "positive regulation of glycolytic fermentation to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0060465", "l": "pharynx development", "d": ["The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002817", "l": "negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "34.513968964599925", "identifiers": [{"i": "GO:0048731", "l": "system development", "d": ["The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050482", "l": "arachidonic acid secretion", "d": ["The controlled release of arachidonic acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070563", "l": "negative regulation of vitamin D receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010062", "l": "negative regulation of trichoblast fate specification", "d": ["Any process that suppresses trichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051953", "l": "negative regulation of amine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:2000045", "l": "regulation of G1/S transition of mitotic cell cycle", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010807", "l": "regulation of synaptic vesicle priming", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045450", "l": "bicoid mRNA localization", "d": ["Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990428", "l": "miRNA transport", "d": ["The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905225", "l": "response to thyrotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.196521192641157", "identifiers": [{"i": "GO:0002444", "l": "myeloid leukocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a myeloid leukocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000387", "l": "spliceosomal snRNP assembly", "d": ["The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032062", "l": "positive regulation of translation in response to osmotic stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060166", "l": "olfactory pit development", "d": ["The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035544", "l": "negative regulation of SNARE complex assembly", "d": ["Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002556", "l": "serotonin secretion by basophil", "d": ["The regulated release of serotonin by a basophil or group of basophils."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044581", "l": "butyryl-CoA catabolic process to butyrate", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.423950427221243", "identifiers": [{"i": "GO:0060606", "l": "tube closure", "d": ["Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035045", "l": "sperm plasma membrane disassembly", "d": ["The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010935", "l": "regulation of macrophage cytokine production", "d": ["Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000648", "l": "positive regulation of stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070587", "l": "regulation of cell-cell adhesion involved in gastrulation", "d": ["Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002870", "l": "T cell anergy", "d": ["Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048382", "l": "mesendoderm development", "d": ["The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090339", "l": "negative regulation of formin-nucleated actin cable assembly", "d": ["Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018096", "l": "peptide cross-linking via S-(2-aminovinyl)-D-cysteine", "d": ["The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014863", "l": "detection of inactivity", "d": ["The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014071", "l": "response to cycloalkane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072497", "l": "mesenchymal stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. 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The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051132", "l": "NK T cell activation", "d": ["The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.528717747115309", "identifiers": [{"i": "GO:0009583", "l": "detection of light stimulus", "d": ["The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035781", "l": "CD86 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110109", "l": "negative regulation of imaginal disc-derived wing vein specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010044", "l": "response to aluminum ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904634", "l": "negative regulation of podocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902559", "l": "3'-phospho-5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071432", "l": "peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035779", "l": "angioblast cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044572", "l": "[4Fe-4S] cluster assembly", "d": ["The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017193", "l": "N-terminal peptidyl-glycine acetylation", "d": ["The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044812", "l": "fermentative hydrogen production", "d": ["The fermentation of organic substances with a net release of hydrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140539", "l": "regulation of melanotic encapsulation of foreign target", "d": ["Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031621", "l": "negative regulation of fever generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0019321", "l": "pentose metabolic process", "d": ["The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0051189", "l": "prosthetic group metabolic process", "d": ["The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006185", "l": "dGDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.390126070323255", "identifiers": [{"i": "GO:0032774", "l": "RNA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071891", "l": "N-terminal peptidyl-proline dimethylation involved in translation", "d": ["An N-terminal peptidyl-proline dimethylation process that contributes to translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019435", "l": "sophorosyloxydocosanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062134", "l": "positive regulation of L-glutamine biosynthetic process", "d": ["Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044579", "l": "butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903843", "l": "cellular response to arsenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098689", "l": "latency-replication decision", "d": ["The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2001056", "l": "positive regulation of cysteine-type endopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000609", "l": "regulation of thyroid hormone generation", "d": ["Any process that modulates the frequency, rate or extent of thyroid hormone generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031174", "l": "lifelong otolith mineralization", "d": ["The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903537", "l": "meiotic cell cycle process involved in oocyte maturation", "d": ["Any meiotic cell cycle process that is involved in oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001001", "l": "negative regulation of xylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901591", "l": "regulation of double-strand break repair via break-induced replication", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0000731", "l": "DNA synthesis involved in DNA repair", "d": ["Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.19662106567214", "identifiers": [{"i": "GO:0050778", "l": "positive regulation of immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044500", "l": "envenomation resulting in negative regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000722", "l": "regulation of cardiac vascular smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042542", "l": "response to hydrogen peroxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902863", "l": "regulation of embryonic camera-type eye development", "d": ["Any process that modulates the frequency, rate or extent of embryonic camera-type eye development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039588", "l": "suppression by virus of host antigen processing and presentation", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010662", "l": "regulation of striated muscle cell apoptotic process", "d": ["Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1905476", "l": "negative regulation of protein localization to membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904581", "l": "negative regulation of intracellular mRNA localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061040", "l": "female gonad morphogenesis", "d": ["The process in which a female gonad is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070246", "l": "natural killer cell apoptotic process", "d": ["Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000151", "l": "negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110063", "l": "positive regulation of angiotensin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0046488", "l": "phosphatidylinositol metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072247", "l": "metanephric glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031950", "l": "negative regulation of glucocorticoid catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007383", "l": "specification of segmental identity, antennal segment", "d": ["The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042543", "l": "protein N-linked glycosylation via arginine", "d": ["The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045572", "l": "positive regulation of imaginal disc growth", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035313", "l": "wound healing, spreading of epidermal cells", "d": ["The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002010", "l": "excitation of vasomotor center by baroreceptor signaling", "d": ["The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097051", "l": "establishment of protein localization to endoplasmic reticulum membrane", "d": ["The directed movement of a protein to a specific location in the endoplasmic reticulum membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.688716751039159", "identifiers": [{"i": "GO:0015833", "l": "peptide transport", "d": ["The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019703", "l": "coenzyme A-peptidyl-cysteine covalent linking", "d": ["The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0030166", "l": "proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016256", "l": "N-glycan processing to lysosome", "d": ["The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060755", "l": "negative regulation of mast cell chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032324", "l": "molybdopterin cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1990918", "l": "double-strand break repair involved in meiotic recombination", "d": ["The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0016998", "l": "cell wall macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0033239", "l": "negative regulation of amine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000763", "l": "positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098736", "l": "negative regulation of the force of heart contraction", "d": ["Any process that decreases the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031947", "l": "negative regulation of glucocorticoid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097270", "l": "dishabituation", "d": ["The temporary recovery of response to a stimulus when a novel stimulus is added."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018240", "l": "protein S-linked glycosylation via cysteine", "d": ["The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110032", "l": "positive regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.861052990773892", "identifiers": [{"i": "GO:1901374", "l": "acetate ester transport", "d": ["The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0080091", "l": "regulation of raffinose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1904018", "l": "positive regulation of vasculature development", "d": ["Any process that activates or increases the frequency, rate or extent of vasculature development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120133", "l": "negative regulation of actin cortical patch assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902640", "l": "propan-2-ol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propan-2-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0044539", "l": "long-chain fatty acid import into cell", "d": ["The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904605", "l": "positive regulation of advanced glycation end-product receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001018", "l": "negative regulation of retrograde axon cargo transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905333", "l": "regulation of gastric motility", "d": ["Any process that modulates the frequency, rate or extent of gastric motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0030218", "l": "erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of an erythrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031169", "l": "ferrichrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098958", "l": "retrograde axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904770", "l": "intramembranous bone morphogenesis", "d": ["The developmental process by which an intramembranous bone is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098036", "l": "viral DNA genome packaging, 3' extended cos packaging", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045348", "l": "positive regulation of MHC class II biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006663", "l": "platelet activating factor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900348", "l": "regulation of methane biosynthetic process from methylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006054", "l": "N-acetylneuraminate metabolic process", "d": ["The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034487", "l": "vacuolar amino acid transmembrane transport", "d": ["The process in which an amino acid is transported from one side of the vacuolar membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045955", "l": "negative regulation of calcium ion-dependent exocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010794", "l": "regulation of dolichol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905902", "l": "regulation of mesoderm formation", "d": ["Any process that modulates the frequency, rate or extent of mesoderm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106090", "l": "positive regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110127", "l": "phloem unloading", "d": ["The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0061333", "l": "renal tubule morphogenesis", "d": ["The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015712", "l": "hexose phosphate transport", "d": ["The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032625", "l": "interleukin-21 production", "d": ["The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903241", "l": "U2-type prespliceosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900675", "l": "regulation of F-9775B biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015969", "l": "guanosine tetraphosphate metabolic process", "d": ["The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046232", "l": "carbazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.447681560237257", "identifiers": [{"i": "GO:0006886", "l": "intracellular protein transport", "d": ["The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141017", "l": "effector-mediated induction of cell cycle reactivation in host", "d": ["A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090392", "l": "sepal giant cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901705", "l": "L-isoleucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-isoleucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072757", "l": "cellular response to camptothecin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0065002", "l": "intracellular protein transmembrane transport", "d": ["The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042271", "l": "susceptibility to natural killer cell mediated cytotoxicity", "d": ["The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072322", "l": "protein transport across periplasmic space", "d": ["The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002047", "l": "phenazine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046197", "l": "orcinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097492", "l": "sympathetic neuron axon guidance", "d": ["The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901999", "l": "homogentisate metabolic process", "d": ["The chemical reactions and pathways involving homogentisate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035502", "l": "metanephric part of ureteric bud development", "d": ["The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009249", "l": "protein lipoylation", "d": ["The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0098610", "l": "adhesion between unicellular organisms", "d": ["The attachment of two unicellular organisms to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902201", "l": "negative regulation of bacterial-type flagellum-dependent cell motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072064", "l": "long descending thin limb development", "d": ["The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099555", "l": "trans-synaptic signaling by nitric oxide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021828", "l": "gonadotrophin-releasing hormone neuronal migration to the hypothalamus", "d": ["The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990882", "l": "rRNA acetylation", "d": ["The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046630", "l": "gamma-delta T cell proliferation", "d": ["The expansion of a gamma-delta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060320", "l": "rejection of self pollen", "d": ["The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0051781", "l": "positive regulation of cell division", "d": ["Any process that activates or increases the frequency, rate or extent of cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140237", "l": "translation at presynapse, modulating chemical synaptic transmission", "d": ["Translation that occurs at the presynapse, and that modulates chemical synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006801", "l": "superoxide metabolic process", "d": ["The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009823", "l": "cytokinin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061084", "l": "negative regulation of protein refolding", "d": ["Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090083", "l": "regulation of inclusion body assembly", "d": ["Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051548", "l": "negative regulation of keratinocyte migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048159", "l": "primary oocyte stage", "d": ["The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901280", "l": "D-ribose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010406", "l": "classical arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901125", "l": "candicidin metabolic process", "d": ["The chemical reactions and pathways involving candicidin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044053", "l": "translocation of peptides or proteins into host cell cytoplasm", "d": ["The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045918", "l": "negative regulation of cytolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010522", "l": "regulation of calcium ion transport into cytosol", "d": ["Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902020", "l": "negative regulation of cilium-dependent cell motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902042", "l": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048825", "l": "cotyledon development", "d": ["The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. 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The cotyledons may appear above ground and show photosynthetic activity in the seedling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990911", "l": "response to psychosocial stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032706", "l": "negative regulation of interleukin-22 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048616", "l": "post-embryonic anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032709", "l": "negative regulation of interleukin-25 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090510", "l": "anticlinal cell division", "d": ["A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048098", "l": "antennal joint development", "d": ["The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. 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"biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034672", "l": "anterior/posterior pattern specification involved in pronephros development", "d": ["The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905299", "l": "negative regulation of intestinal epithelial cell development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031061", "l": "negative regulation of histone methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0006661", "l": "phosphatidylinositol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072258", "l": "metanephric interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901410", "l": "regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that modulates the frequency, 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"GO:0098694", "l": "regulation of synaptic vesicle budding from presynaptic endocytic zone membrane", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061015", "l": "snRNA import into nucleus", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000244", "l": "regulation of FtsZ-dependent cytokinesis", "d": ["Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072717", "l": "cellular response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072310", "l": "glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904663", "l": "regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000313", "l": "regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0045444", "l": "fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033069", "l": "ansamycin metabolic process", "d": ["The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034966", "l": "intronic box H/ACA snoRNA processing", "d": ["Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903674", "l": "regulation of cap-dependent translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cap-dependent translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061032", "l": "visceral serous pericardium development", "d": ["The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042160", "l": "lipoprotein modification", "d": ["The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045003", "l": "double-strand break repair via synthesis-dependent strand annealing", "d": ["SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901816", "l": "beta-zeacarotene metabolic process", "d": ["The chemical reactions and pathways involving beta-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075287", "l": "positive regulation of sporangiospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001563", "l": "detection of protozoan", "d": ["The series of events in which a stimulus from a protozoan is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140509", "l": "epithelium-like organization", "d": ["The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006850", "l": "mitochondrial pyruvate transmembrane transport", "d": ["The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0050956", "l": "electroception", "d": ["The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014039", "l": "negative regulation of Schwann cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031987", "l": "locomotion involved in locomotory behavior", "d": ["Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035146", "l": "tube fusion", "d": ["The joining of specific branches of a tubular system to form a continuous network."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039013", "l": "pronephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0075317", "l": "ascus development", "d": ["The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903052", "l": "positive regulation of proteolysis involved in protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0051341", "l": "regulation of oxidoreductase activity", "d": ["Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901956", "l": "positive regulation of retrograde dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0090224", "l": "regulation of spindle organization", "d": ["Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035081", "l": "induction of programmed cell death by hormones", "d": ["Any process induced by hormones that directly activates any of the steps required for programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090253", "l": "convergent extension involved in imaginal disc-derived wing morphogenesis", "d": ["The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046655", "l": "folic acid metabolic process", "d": ["The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048079", "l": "regulation of cuticle pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001061", "l": "D-glycero-D-manno-heptose 7-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080140", "l": "regulation of jasmonic acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0007533", "l": "mating type switching", "d": ["The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0018175", "l": "protein nucleotidylation", "d": ["The addition of a nucleotide to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0090698", "l": "post-embryonic plant morphogenesis", "d": ["The process, occurring after plant embryonic development, by which anatomical structures are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1904238", "l": "pericyte cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001250", "l": "positive regulation of ammonia assimilation cycle", "d": ["Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0043455", "l": "regulation of secondary metabolic process", "d": ["Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0008207", "l": "C21-steroid hormone metabolic process", "d": ["The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010064", "l": "embryonic shoot morphogenesis", "d": ["The process in which the anatomical structures of embryonic shoot are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901827", "l": "zeaxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeaxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0070944", "l": "neutrophil-mediated killing of bacterium", "d": ["The directed killing of a bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019678", "l": "propionate metabolic process, methylmalonyl pathway", "d": ["The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.150826422598314", "identifiers": [{"i": "GO:0008610", "l": "lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150092", "l": "regulation of synaptic scaling", "d": ["A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060664", "l": "epithelial cell proliferation involved in salivary gland morphogenesis", "d": ["The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060194", "l": "regulation of antisense RNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0033077", "l": "T cell differentiation in thymus", "d": ["The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036352", "l": "histone H2A-K15 ubiquitination", "d": ["The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904226", "l": "regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903830", "l": "magnesium ion transmembrane transport", "d": ["The directed movement of magnesium ion across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001317", "l": "kojic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kojic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008407", "l": "chaeta morphogenesis", "d": ["The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034288", "l": "detection of disaccharide stimulus", "d": ["The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045541", "l": "negative regulation of cholesterol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140121", "l": "Lewy body formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Lewy body."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0006470", "l": "protein dephosphorylation", "d": ["The process of removing one or more phosphoric residues from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031037", "l": "myosin II filament disassembly", "d": ["The disassembly of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001777", "l": "T cell homeostatic proliferation", "d": ["The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072577", "l": "endothelial cell apoptotic process", "d": ["Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042852", "l": "L-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0075259", "l": "spore-bearing structure development", "d": ["The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051790", "l": "short-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070376", "l": "regulation of ERK5 cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000055", "l": "ribosomal large subunit export from nucleus", "d": ["The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048723", "l": "clypeus development", "d": ["The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010693", "l": "negative regulation of alkaline phosphatase activity", "d": ["Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0072234", "l": "metanephric nephron tubule development", "d": ["The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000613", "l": "negative regulation of thyroid-stimulating hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035503", "l": "ureter part of ureteric bud development", "d": ["The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000063", "l": "positive regulation of ureter smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002049", "l": "pyoverdine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019445", "l": "tyrosine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010493", "l": "Lewis a epitope biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0032370", "l": "positive regulation of lipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034508", "l": "centromere complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033367", "l": "protein localization to mast cell secretory granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904975", "l": "response to bleomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019298", "l": "coenzyme B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007074", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070297", "l": "regulation of phosphorelay signal transduction system", "d": ["Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019397", "l": "gallate catabolic process via 2-pyrone-4,6-dicarboxylate", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003065", "l": "positive regulation of heart rate by epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044375", "l": "regulation of peroxisome size", "d": ["Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035479", "l": "angioblast cell migration from lateral mesoderm to midline", "d": ["The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000433", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter by glucose", "d": ["A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051946", "l": "regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090424", "l": "phytochelatin-metal-sulfur complex formation", "d": ["A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902689", "l": "negative regulation of NAD metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021841", "l": "chemoattraction involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.986287646268401", "identifiers": [{"i": "GO:0002252", "l": "immune effector process", "d": ["Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032431", "l": "activation of phospholipase A2 activity", "d": ["Any process that initiates the activity of the inactive enzyme phospholipase A2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018979", "l": "trichloroethylene metabolic process", "d": ["The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060196", "l": "positive regulation of antisense RNA transcription", "d": ["Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060490", "l": "lateral sprouting involved in lung morphogenesis", "d": ["The process in which a branch forms along the side of the lung epithelial tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032683", "l": "negative regulation of connective tissue growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071238", "l": "cellular response to brefeldin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0022401", "l": "negative adaptation of signaling pathway", "d": ["The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090189", "l": "regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000220", "l": "regulation of pseudohyphal growth", "d": ["Any process that modulates the frequency, rate or extent of pseudohyphal growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901353", "l": "positive regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0032274", "l": "gonadotropin secretion", "d": ["The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071603", "l": "endothelial cell-cell adhesion", "d": ["The attachment of an endothelial cell to another endothelial cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045708", "l": "regulation of larval salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010705", "l": "meiotic DNA double-strand break processing involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010560", "l": "positive regulation of glycoprotein biosynthetic process", "d": ["Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:1902440", "l": "protein localization to mitotic spindle pole body", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090209", "l": "negative regulation of triglyceride metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0060048", "l": "cardiac muscle contraction", "d": ["Muscle contraction of cardiac muscle tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000206", "l": "regulation of ribosomal small subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900929", "l": "regulation of L-tyrosine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010994", "l": "free ubiquitin chain polymerization", "d": ["The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900768", "l": "fonsecin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fonsecin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000468", "l": "generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090001", "l": "replication fork arrest at tRNA locus", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046476", "l": "glycosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030577", "l": "Lands organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000755", "l": "positive regulation of sphingomyelin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003266", "l": "regulation of secondary heart field cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044250", "l": "negative regulation of metabolic activity involved in hibernation", "d": ["The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903965", "l": "monounsaturated fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042377", "l": "vitamin K catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120056", "l": "large intestinal transit", "d": ["Migration of ingested material along the length of the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0000302", "l": "response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046004", "l": "positive regulation of syncytial blastoderm mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905636", "l": "positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044871", "l": "negative regulation by host of viral glycoprotein metabolic process", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006489", "l": "dolichyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018414", "l": "nickel incorporation into metallo-sulfur cluster", "d": ["The incorporation of nickel into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071397", "l": "cellular response to cholesterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0033696", "l": "heterochromatin boundary formation", "d": ["A process that forms a boundary that limits the spreading of heterochromatin along a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000813", "l": "negative regulation of barbed-end actin filament capping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043980", "l": "histone H2B-K12 acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904758", "l": "protein localization to new growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a new growing cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045057", "l": "cisternal progression", "d": ["The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050857", "l": "positive regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071235", "l": "cellular response to proline", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060267", "l": "positive regulation of respiratory burst", "d": ["Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160025", "l": "sensory perception of itch", "d": ["A sensory perception which causes the desire or reflex to scratch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019409", "l": "aerobic respiration, using ammonia as electron donor", "d": ["The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055020", "l": "positive regulation of cardiac muscle fiber development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071165", "l": "GINS complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039015", "l": "cell proliferation involved in pronephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002619", "l": "regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033512", "l": "L-lysine catabolic process to acetyl-CoA via saccharopine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.70470389845471", "identifiers": [{"i": "GO:0043648", "l": "dicarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905066", "l": "regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048689", "l": "formation of growth cone in injured axon", "d": ["The formation of a growth cone in an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000107", "l": "negative regulation of leukocyte apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905417", "l": "negative regulation of amoeboid sperm motility", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:1902749", "l": "regulation of cell cycle G2/M phase transition", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010239", "l": "chloroplast mRNA processing", "d": ["Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1903789", "l": "regulation of amino acid transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of amino acid transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071409", "l": "cellular response to cycloheximide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0150147", "l": "cell-cell junction disassembly", "d": ["The disaggregation of a cell-cell junction into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070669", "l": "response to interleukin-2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902290", "l": "positive regulation of defense response to oomycetes", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.866957504416824", "identifiers": [{"i": "GO:0033043", "l": "regulation of organelle organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000713", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0014854", "l": "response to inactivity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046893", "l": "iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation", "d": ["The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902628", "l": "positive regulation of assembly of large subunit precursor of preribosome", "d": ["Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099045", "l": "viral extrusion", "d": ["The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035285", "l": "appendage segmentation", "d": ["Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0050746", "l": "regulation of lipoprotein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048536", "l": "spleen development", "d": ["The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055109", "l": "invagination involved in gastrulation with mouth forming second", "d": ["The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903689", "l": "regulation of wound healing, spreading of epidermal cells", "d": ["Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000077", "l": "negative regulation of type B pancreatic cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140913", "l": "viral release via disruption of host peptidoglycan cell wall", "d": ["The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903933", "l": "negative regulation of DNA primase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001981", "l": "baroreceptor detection of arterial stretch", "d": ["The series of events by which the change in diameter of an artery is detected and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900962", "l": "regulation of methanophenazine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901524", "l": "regulation of mitophagy", "d": ["Any process that modulates the frequency, rate or extent of macromitophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035382", "l": "sterol transmembrane transport", "d": ["The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904987", "l": "regulation of endothelial cell activation", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.06015934163878", "identifiers": [{"i": "GO:0071407", "l": "cellular response to organic cyclic compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036378", "l": "calcitriol biosynthetic process from calciol", "d": ["Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019635", "l": "2-aminoethylphosphonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018292", "l": "molybdenum incorporation via L-cysteinyl molybdopterin", "d": ["The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060517", "l": "epithelial cell proliferation involved in prostatic bud elongation", "d": ["The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009942", "l": "longitudinal axis specification", "d": ["The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035462", "l": "determination of left/right asymmetry in diencephalon", "d": ["The establishment of the diencephalon with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048773", "l": "erythrophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010115", "l": "regulation of abscisic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046708", "l": "IDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070885", "l": "negative regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072760", "l": "cellular response to GW 7647", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.85341545293393", "identifiers": [{"i": "GO:0060350", "l": "endochondral bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089705", "l": "protein localization to outer membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036147", "l": "rumination", "d": ["A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000707", "l": "meiotic DNA recombinase assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001194", "l": "regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032289", "l": "central nervous system myelin formation", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905025", "l": "negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048805", "l": "imaginal disc-derived genitalia morphogenesis", "d": ["The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052165", "l": "symbiont defense to host-produced phytoalexin", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0006705", "l": "mineralocorticoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0051782", "l": "negative regulation of cell division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904138", "l": "positive regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0055127", "l": "vibrational conductance of sound to the inner ear", "d": ["The transmission of vibrations via ossicles to the inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000490", "l": "negative regulation of hepatic stellate cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035291", "l": "specification of segmental identity, intercalary segment", "d": ["The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090153", "l": "regulation of sphingolipid biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051556", "l": "leucoanthocyanidin metabolic process", "d": ["The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033326", "l": "cerebrospinal fluid secretion", "d": ["The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010431", "l": "seed maturation", "d": ["A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048356", "l": "root epithelial mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901111", "l": "actinorhodin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of actinorhodin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902365", "l": "positive regulation of protein localization to spindle pole body", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903999", "l": "negative regulation of eating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0060096", "l": "serotonin secretion, neurotransmission", "d": ["The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021586", "l": "pons maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0050819", "l": "negative regulation of coagulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900439", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048817", "l": "negative regulation of hair follicle maturation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060399", "l": "positive regulation of growth hormone receptor signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.349675134728187", "identifiers": [{"i": "GO:0042981", "l": "regulation of apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009442", "l": "allantoin assimilation pathway", "d": ["The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061854", "l": "positive regulation of neuroblast migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuroblast migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090273", "l": "regulation of somatostatin secretion", "d": ["Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007066", "l": "female meiosis sister chromatid cohesion", "d": ["The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140731", "l": "regulation of amphiregulin production", "d": ["Any process that modulates the frequency, rate, or extent of production of amphiregulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009051", "l": "pentose-phosphate shunt, oxidative branch", "d": ["The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019416", "l": "polythionate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120006", "l": "regulation of glutamatergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904870", "l": "negative regulation of protein localization to Cajal body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048772", "l": "leucophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007253", "l": "cytoplasmic sequestering of NF-kappaB", "d": ["The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043042", "l": "amino acid adenylylation by nonribosomal peptide synthase", "d": ["Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061470", "l": "T follicular helper cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0044843", "l": "cell cycle G1/S phase transition", "d": ["The cell cycle process by which a cell in G1 phase commits to S phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042360", "l": "vitamin E metabolic process", "d": ["The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.428314874697286", "identifiers": [{"i": "GO:0006479", "l": "protein methylation", "d": ["The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903529", "l": "negative regulation of dCDP biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120197", "l": "mucociliary clearance", "d": ["The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903088", "l": "5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport", "d": ["The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001572", "l": "lactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0046434", "l": "organophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035676", "l": "anterior lateral line neuromast hair cell development", "d": ["The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090194", "l": "negative regulation of glomerulus development", "d": ["Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051616", "l": "regulation of histamine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002399", "l": "MHC class II protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039006", "l": "pronephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046521", "l": "sphingoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0051329", "l": "mitotic interphase", "d": ["The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0016444", "l": "somatic cell DNA recombination", "d": ["Recombination occurring within or between DNA molecules in somatic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.142587795408666", "identifiers": [{"i": "GO:0044248", "l": "cellular catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019558", "l": "histidine catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904652", "l": "protein localization to cell division site involved in cell separation after cytokinesis", "d": ["Any protein localization to cell division site that is involved in cell separation after cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0140418", "l": "effector-mediated modulation of host process by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045964", "l": "positive regulation of dopamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044492", "l": "envenomation resulting in modulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010785", "l": "clathrin coating of Golgi vesicle, plasma membrane to endosome targeting", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018137", "l": "peptide cross-linking via glycine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002004", "l": "secretion of vasopressin involved in fast regulation of systemic arterial blood pressure", "d": ["The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051873", "l": "killing by host of symbiont cells", "d": ["Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0120110", "l": "interphase mitotic telomere clustering", "d": ["The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904170", "l": "regulation of bleb assembly", "d": ["Any process that modulates the frequency, rate or extent of bleb assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900328", "l": "negative regulation of mannotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097336", "l": "response to risperidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046078", "l": "dUMP metabolic process", "d": ["The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048021", "l": "regulation of melanin biosynthetic process", "d": ["Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903423", "l": "positive regulation of synaptic vesicle recycling", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904141", "l": "positive regulation of microglial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0086001", "l": "cardiac muscle cell action potential", "d": ["An action potential that occurs in a cardiac muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015685", "l": "ferric-enterobactin import into cell", "d": ["A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042572", "l": "retinol metabolic process", "d": ["The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0007398", "l": "ectoderm development", "d": ["The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. 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Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904535", "l": "positive regulation of telomeric loop disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060617", "l": "positive regulation of mammary placode formation by mesenchymal-epithelial signaling", "d": ["Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0051447", "l": "negative regulation of meiotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0070783", "l": "growth of unicellular organism as a thread of attached cells", "d": ["A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905175", "l": "negative regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002364", "l": "NK T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming an NK T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001302", "l": "lipoxin A4 metabolic process", "d": ["The chemical reactions and pathways involving lipoxin A4. 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"92.728541327098611", "identifiers": [{"i": "GO:0072718", "l": "response to cisplatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0072524", "l": "pyridine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903016", "l": "negative regulation of exo-alpha-sialidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035506", "l": "negative regulation of myosin light chain kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018961", "l": "pentachlorophenol metabolic process", "d": ["The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030011", "l": "maintenance of cell polarity", "d": ["The maintenance of established anisotropic intracellular organization or cell growth patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071306", "l": "cellular response to vitamin E", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904763", "l": "chaperone-mediated autophagy translocation complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034638", "l": "phosphatidylcholine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0051293", "l": "establishment of spindle localization", "d": ["The directed movement of the spindle to a specific location in the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007526", "l": "larval somatic muscle development", "d": ["The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031065", "l": "positive regulation of histone deacetylation", "d": ["Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048279", "l": "vesicle fusion with endoplasmic reticulum", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071251", "l": "cellular response to silicon dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021563", "l": "glossopharyngeal nerve development", "d": ["Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016257", "l": "N-glycan processing to secreted and cell-surface N-glycans", "d": ["The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046711", "l": "GDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903793", "l": "positive regulation of monoatomic anion transport", "d": ["Any process that activates or increases the frequency, rate or extent of anion transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901352", "l": "negative regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0045995", "l": "regulation of embryonic development", "d": ["Any process that modulates the frequency, rate or extent of embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001148", "l": "regulation of dipeptide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905455", "l": "positive regulation of myeloid progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051150", "l": "regulation of smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050650", "l": "chondroitin sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061047", "l": "positive regulation of branching involved in lung morphogenesis", "d": ["Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061681", "l": "Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009095", "l": "aromatic amino acid family biosynthetic process, prephenate pathway", "d": ["The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120324", "l": "procyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014891", "l": "striated muscle atrophy", "d": ["A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007478", "l": "leg disc morphogenesis", "d": ["The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901427", "l": "response to propan-1-ol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0044344", "l": "cellular response to fibroblast growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032251", "l": "positive regulation of adenosine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045577", "l": "regulation of B cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098969", "l": "neurotransmitter receptor transport to postsynaptic membrane", "d": ["The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048329", "l": "negative regulation of axial mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019258", "l": "4-nitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.368095522595297", "identifiers": [{"i": "GO:0016125", "l": "sterol metabolic process", "d": ["The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031283", "l": "negative regulation of guanylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021999", "l": "neural plate anterior/posterior regionalization", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903967", "l": "response to micafungin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090155", "l": "negative regulation of sphingolipid biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901399", "l": "negative regulation of transforming growth factor beta3 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901869", "l": "ecgonine methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecgonine methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0002343", "l": "peripheral B cell selection", "d": ["Any B cell selection process that occurs in the periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045693", "l": "positive regulation of embryo sac central cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060327", "l": "cytoplasmic actin-based contraction involved in cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.588454143880355", "identifiers": [{"i": "GO:0045597", "l": "positive regulation of cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0002260", "l": "lymphocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009663", "l": "plasmodesma organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062170", "l": "lutein metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009876", "l": "pollen adhesion", "d": ["The process in which pollen deposited on the stigma adheres to cells of the stigma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046269", "l": "toluene-4-sulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0017038", "l": "protein import", "d": ["The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905188", "l": "positive regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000654", "l": "regulation of cellular response to testosterone stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044817", "l": "hydrogen generation via biophotolysis", "d": ["The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007629", "l": "flight behavior", "d": ["The response to external or internal stimuli that results in the locomotory process of flight. 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The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060003", "l": "copper ion export", "d": ["The directed movement of copper ions out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061856", "l": "Golgi calcium ion transmembrane transport", "d": ["A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0031554", "l": "regulation of termination of DNA-templated transcription", "d": ["Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903327", "l": "negative regulation of tRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018020", "l": "peptidyl-glutamic acid methylation", "d": ["The addition of a methyl group to a glutamic acid residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042361", "l": "menaquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046606", "l": "negative regulation of centrosome cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080163", "l": "regulation of protein serine/threonine phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006743", "l": "ubiquinone metabolic process", "d": ["The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0045765", "l": "regulation of angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0002688", "l": "regulation of leukocyte chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030843", "l": "negative regulation of intermediate filament depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902385", "l": "glycyrrhetinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061674", "l": "gap filling involved in double-strand break repair via nonhomologous end joining", "d": ["Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901333", "l": "positive regulation of lateral root development", "d": ["Any process that activates or increases the frequency, rate or extent of lateral root development."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0044553", "l": "modulation of biological quality in another organism", "d": ["Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019348", "l": "dolichol metabolic process", "d": ["The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061006", "l": "regulation of cell proliferation involved in kidney morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0007538", "l": "primary sex determination", "d": ["The sex determination process that results in the initial specification of sexual status of an individual organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003366", "l": "cell-matrix adhesion involved in ameboidal cell migration", "d": ["The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021688", "l": "cerebellar molecular layer formation", "d": ["The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905557", "l": "regulation of mitotic nuclear envelope disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900748", "l": "positive regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0048532", "l": "anatomical structure arrangement", "d": ["The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031142", "l": "induction of conjugation upon nitrogen starvation", "d": ["The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010097", "l": "specification of stamen identity", "d": ["The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904076", "l": "regulation of estrogen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of estrogen biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905834", "l": "response to pyrimidine ribonucleotide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046896", "l": "N-terminal peptidyl-leucine methylation", "d": ["The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902204", "l": "positive regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0006805", "l": "xenobiotic metabolic process", "d": ["The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905343", "l": "regulation of cohesin unloading", "d": ["Any process that modulates the frequency, rate or extent of cohesin unloading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904221", "l": "negative regulation of serine C-palmitoyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006238", "l": "CMP salvage", "d": ["Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051935", "l": "glutamate reuptake", "d": ["The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0160015", "l": "platelet rolling", "d": ["Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006602", "l": "creatinine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009114", "l": "hypoxanthine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021635", "l": "trigeminal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099577", "l": "regulation of translation at presynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990403", "l": "embryonic brain development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900509", "l": "regulation of pentose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902891", "l": "negative regulation of root hair elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061343", "l": "cell adhesion involved in heart morphogenesis", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904694", "l": "negative regulation of vascular associated smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1902019", "l": "regulation of cilium-dependent cell motility", "d": ["Any process that modulates the frequency, rate or extent of cilium-dependent cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019281", "l": "L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051659", "l": "maintenance of mitochondrion location", "d": ["Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0120169", "l": "detection of cold stimulus involved in thermoception", "d": ["The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0072528", "l": "pyrimidine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046672", "l": "positive regulation of compound eye retinal cell programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019578", "l": "aldaric acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043374", "l": "CD8-positive, alpha-beta T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0015732", "l": "prostaglandin transport", "d": ["The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.58597274768276", "identifiers": [{"i": "GO:0006913", "l": "nucleocytoplasmic transport", "d": ["The directed movement of molecules between the nucleus and the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.011510474046766", "identifiers": [{"i": "GO:0055085", "l": "transmembrane transport", "d": ["The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071605", "l": "monocyte chemotactic protein-1 production", "d": ["The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000355", "l": "negative regulation of ovarian follicle development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034123", "l": "positive regulation of toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072021", "l": "ascending thin limb development", "d": ["The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021725", "l": "superior raphe nucleus development", "d": ["The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036250", "l": "peroxisome transport along microtubule", "d": ["The directed movement of a peroxisome along a microtubule, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036261", "l": "7-methylguanosine cap hypermethylation", "d": ["Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900294", "l": "regulation of heptasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of heptasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160037", "l": "negative regulation of postsynaptic density assembly", "d": ["Any process that decreases the rate, frequency, or extent of postsynaptic density assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048624", "l": "plantlet formation on parent plant", "d": ["The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018002", "l": "N-terminal peptidyl-glutamic acid acetylation", "d": ["The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001079", "l": "nitrogen catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0051222", "l": "positive regulation of protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0034755", "l": "iron ion transmembrane transport", "d": ["A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0017156", "l": "calcium-ion regulated exocytosis", "d": ["The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071312", "l": "cellular response to alkaloid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001694", "l": "histamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010780", "l": "meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031922", "l": "pyridoxamine transport", "d": ["The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052080", "l": "perturbation of host MAPK signal transduction pathway", "d": ["A process in which a symbiont alters or subverts a MAP kinase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016268", "l": "O-glycan processing, core 2", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001293", "l": "malonyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0007444", "l": "imaginal disc development", "d": ["The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002243", "l": "detection of parasitic plant", "d": ["The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002549", "l": "negative regulation of plasma kallikrein-kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099116", "l": "tRNA 5'-end processing", "d": ["The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042939", "l": "tripeptide transport", "d": ["The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905047", "l": "mitotic spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035229", "l": "positive regulation of glutamate-cysteine ligase activity", "d": ["Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.099244958558103", "identifiers": [{"i": "GO:0055082", "l": "intracellular chemical homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090235", "l": "regulation of metaphase plate congression", "d": ["Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000504", "l": "positive regulation of blood vessel remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061034", "l": "olfactory bulb mitral cell layer development", "d": ["The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003330", "l": "regulation of extracellular matrix constituent secretion", "d": ["Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071288", "l": "cellular response to mercury ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900659", "l": "negative regulation of emericellamide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150033", "l": "negative regulation of protein localization to lysosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002737", "l": "negative regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0000753", "l": "cell morphogenesis involved in conjugation with cellular fusion", "d": ["The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900160", "l": "plastid chromosome packaging", "d": ["A process in which plastidial DNA and associated proteins organize into a compact, orderly structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032635", "l": "interleukin-6 production", "d": ["The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0110100", "l": "spindle pole body separation", "d": ["The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018290", "l": "iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide", "d": ["The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001762", "l": "beta-alanine transport", "d": ["The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0030850", "l": "prostate gland development", "d": ["The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0001708", "l": "cell fate specification", "d": ["The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009641", "l": "shade avoidance", "d": ["Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001152", "l": "negative regulation of renal water transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:1903320", "l": "regulation of protein modification by small protein conjugation or removal", "d": ["Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:2000134", "l": "negative regulation of G1/S transition of mitotic cell cycle", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0061217", "l": "regulation of mesonephros development", "d": ["Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033567", "l": "DNA replication, Okazaki fragment processing", "d": ["The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046490", "l": "isopentenyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902297", "l": "cell cycle DNA replication DNA unwinding", "d": ["Any DNA unwinding that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046665", "l": "amnioserosa maintenance", "d": ["Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032209", "l": "positive regulation of telomere maintenance via recombination", "d": ["Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046773", "l": "suppression by virus of host translation termination", "d": ["Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900105", "l": "negative regulation of hyaluranon cable assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003403", "l": "optic vesicle formation", "d": ["The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019042", "l": "viral latency", "d": ["The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905289", "l": "regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019803", "l": "peptidyl-aspartic acid carboxylation", "d": ["The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010190", "l": "cytochrome b6f complex assembly", "d": ["Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0099563", "l": "modification of synaptic structure", "d": ["Any process that modifies the structure/morphology of a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006712", "l": "mineralocorticoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000480", "l": "negative regulation of cAMP-dependent protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0002251", "l": "organ or tissue specific immune response", "d": ["An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035187", "l": "hatching behavior", "d": ["The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021944", "l": "neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration", "d": ["The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0009657", "l": "plastid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098968", "l": "neurotransmitter receptor transport postsynaptic membrane to endosome", "d": ["Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905300", "l": "positive regulation of intestinal epithelial cell development", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0035924", "l": "cellular response to vascular endothelial growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000345", "l": "regulation of hepatocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120270", "l": "regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032971", "l": "regulation of muscle filament sliding", "d": ["Any process that modulates the frequency, rate or extent of muscle filament sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097041", "l": "phenolic phthiocerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034608", "l": "vulval location", "d": ["Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036290", "l": "protein trans-autophosphorylation", "d": ["The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034315", "l": "regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006654", "l": "phosphatidic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002692", "l": "negative regulation of cellular extravasation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000971", "l": "negative regulation of detection of glucose", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010971", "l": "positive regulation of G2/M transition of mitotic cell cycle", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048372", "l": "lateral mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become a lateral mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060268", "l": "negative regulation of respiratory burst", "d": ["Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014725", "l": "regulation of extraocular skeletal muscle development", "d": ["Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035088", "l": "establishment or maintenance of apical/basal cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0010721", "l": "negative regulation of cell development", "d": ["Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021995", "l": "neuropore closure", "d": ["The process of joining together the neural folds at either end of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061052", "l": "negative regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0071763", "l": "nuclear membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902915", "l": "negative regulation of protein polyubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0060271", "l": "cilium assembly", "d": ["The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}, {"i": "REACT:R-HSA-5617833.2", "d": []}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904620", "l": "cellular response to dimethyl sulfoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052889", "l": "9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene", "d": ["The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902955", "l": "positive regulation of early endosome to recycling endosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009441", "l": "glycolate metabolic process", "d": ["The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098913", "l": "membrane depolarization during ventricular cardiac muscle cell action potential", "d": ["The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051614", "l": "inhibition of serotonin uptake", "d": ["Any process that prevents the activation of the directed movement of serotonin into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009436", "l": "glyoxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0030433", "l": "ubiquitin-dependent ERAD pathway", "d": ["The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072209", "l": "metanephric mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015808", "l": "L-alanine transport", "d": ["The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045960", "l": "positive regulation of complement activation, classical pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060651", "l": "regulation of epithelial cell proliferation involved in mammary gland bud elongation", "d": ["Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0035272", "l": "exocrine system development", "d": ["Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902802", "l": "regulation of siRNA-dependent facultative heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046586", "l": "regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900362", "l": "positive regulation of pentasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of pentasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048172", "l": "regulation of short-term neuronal synaptic plasticity", "d": ["A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0031396", "l": "regulation of protein ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048311", "l": "mitochondrion distribution", "d": ["Any process that establishes the spatial arrangement of mitochondria between and within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072344", "l": "rescue of stalled ribosome", "d": ["A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090260", "l": "negative regulation of retinal ganglion cell axon guidance", "d": ["Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061168", "l": "regulation of hair follicle placode formation", "d": ["Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140433", "l": "regulation of protein localization to meiotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045854", "l": "positive regulation of bicoid mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0060973", "l": "cell migration involved in heart development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010025", "l": "wax biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003346", "l": "epicardium-derived cell migration to the myocardium", "d": ["The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0110154", "l": "RNA decapping", "d": ["Cleavage of the 5'-cap of an RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901794", "l": "3-(3-hydroxyphenyl)propanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016100", "l": "monoterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.981509651071725", "identifiers": [{"i": "GO:0031324", "l": "negative regulation of cellular metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046938", "l": "phytochelatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006234", "l": "TTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001286", "l": "regulation of caveolin-mediated endocytosis", "d": ["Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042744", "l": "hydrogen peroxide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901277", "l": "tartrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tartrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048464", "l": "flower calyx development", "d": ["The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0036093", "l": "germ cell proliferation", "d": ["The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902617", "l": "response to fluoride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034376", "l": "conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle", "d": ["The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030388", "l": "fructose 1,6-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072742", "l": "SAGA complex localization to transcription regulatory region", "d": ["Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003189", "l": "aortic valve formation", "d": ["The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0001580", "l": "detection of chemical stimulus involved in sensory perception of bitter taste", "d": ["The series of events required for a bitter taste stimulus to be received and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030502", "l": "negative regulation of bone mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036120", "l": "cellular response to platelet-derived growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010360", "l": "negative regulation of anion channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007307", "l": "eggshell chorion gene amplification", "d": ["Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009091", "l": "homoserine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002110", "l": "cotranscriptional mitochondrial rRNA nucleotide insertion", "d": ["The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002841", "l": "negative regulation of T cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060873", "l": "anterior semicircular canal development", "d": ["The progession of the anterior semicircular canal from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902524", "l": "positive regulation of protein K48-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905024", "l": "regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021754", "l": "facial nucleus development", "d": ["The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140206", "l": "dipeptide import across plasma membrane", "d": ["The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019886", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903671", "l": "negative regulation of sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904116", "l": "response to vasopressin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039526", "l": "modulation by virus of host apoptotic process", "d": ["Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904179", "l": "positive regulation of adipose tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of adipose tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0000080", "l": "mitotic G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050653", "l": "chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901161", "l": "primary amino compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary amino compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046070", "l": "dGTP metabolic process", "d": ["The chemical reactions and pathways involving dGTP, guanosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052075", "l": "induction by symbiont of host jasmonic acid-mediated defense response", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061238", "l": "establishment of planar polarity involved in mesonephric nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019452", "l": "L-cysteine catabolic process to taurine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0044650", "l": "adhesion of symbiont to host cell", "d": ["The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034078", "l": "butanediol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002882", "l": "positive regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070596", "l": "(1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0098901", "l": "regulation of cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. 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A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097334", "l": "response to perphenazine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0051047", "l": "positive regulation of secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0014819", "l": "regulation of skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002051", "l": "osteoblast fate commitment", "d": ["The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009192", "l": "deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0016233", "l": "telomere capping", "d": ["A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031171", "l": "ferricrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060780", "l": "intercalary leaflet morphogenesis", "d": ["The process in which the intercalary leaflet attains its shape. 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An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0036124", "l": "histone H3-K9 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002729", "l": "positive regulation of natural killer cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0007132", "l": "meiotic metaphase I", "d": ["The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900843", "l": "regulation of monodictyphenone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031274", "l": "positive regulation of pseudopodium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903709", "l": "uterine gland development", "d": ["The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015944", "l": "formate oxidation", "d": ["The chemical reactions and pathways by which formate is converted to CO2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043610", "l": "regulation of carbohydrate utilization", "d": ["Any process that modulates the frequency, rate or extent of carbohydrate utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902960", "l": "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021770", "l": "parahippocampal gyrus development", "d": ["The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090026", "l": "positive regulation of monocyte chemotaxis", "d": ["Any process that increases the frequency, rate, or extent of monocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002657", "l": "positive regulation of tolerance induction to nonself antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034384", "l": "high-density lipoprotein particle clearance", "d": ["The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044206", "l": "UMP salvage", "d": ["Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010462", "l": "regulation of light-activated voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:1903037", "l": "regulation of leukocyte cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061544", "l": "peptide secretion, neurotransmission", "d": ["The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006220", "l": "pyrimidine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901782", "l": "p-cumate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cumate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032613", "l": "interleukin-10 production", "d": ["The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052110", "l": "occlusion by symbiont of host vascular system", "d": ["The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030202", "l": "heparin metabolic process", "d": ["The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003120", "l": "regulation of vasoconstriction by circulating epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1904304", "l": "regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031917", "l": "negative regulation of synaptic metaplasticity", "d": ["A process that decreases synaptic metaplasticity. 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Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0017085", "l": "response to insecticide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060886", "l": "clearance of cells from fusion plate by epithelial to mesenchymal transition", "d": ["The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0098976", "l": "excitatory chemical synaptic transmission", "d": ["Synaptic transmission that results in an excitatory postsynaptic potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070409", "l": "carbamoyl phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901606", "l": "alpha-amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0045920", "l": "negative regulation of exocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051409", "l": "response to nitrosative stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032298", "l": "positive regulation of DNA-templated DNA replication initiation", "d": ["Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033634", "l": "positive regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120165", "l": "perithecium development", "d": ["The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060718", "l": "chorionic trophoblast cell differentiation", "d": ["The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048398", "l": "intermediate mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060905", "l": "regulation of induction of conjugation upon nitrogen starvation", "d": ["Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903585", "l": "negative regulation of histone deubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070911", "l": "global genome nucleotide-excision repair", "d": ["The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900093", "l": "positive regulation of raffinose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0033523", "l": "histone H2B ubiquitination", "d": ["The modification of histone H2B by addition of ubiquitin groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904732", "l": "regulation of electron transfer activity", "d": ["Any process that modulates the frequency, rate or extent of electron transfer activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903969", "l": "regulation of response to macrophage colony-stimulating factor", "d": ["Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0017012", "l": "protein-phytochromobilin linkage", "d": ["The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021597", "l": "central nervous system structural organization", "d": ["The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071257", "l": "cellular response to electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007023", "l": "post-chaperonin tubulin folding pathway", "d": ["Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039014", "l": "cell differentiation involved in pronephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900057", "l": "positive regulation of leaf senescence", "d": ["Any process that activates or increases the frequency, rate or extent of leaf senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900482", "l": "positive regulation of diacylglycerol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052776", "l": "diacetylchitobiose catabolic process to glucosamine and acetate", "d": ["The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.748105804263417", "identifiers": [{"i": "GO:0001510", "l": "RNA methylation", "d": ["Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001133", "l": "methane biosynthetic process from methanethiol", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a methanethiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905899", "l": "regulation of smooth muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902039", "l": "negative regulation of seed dormancy process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036486", "l": "ventral trunk neural crest cell migration", "d": ["The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010600", "l": "regulation of auxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.027135950914058", "identifiers": [{"i": "GO:0051234", "l": "establishment of localization", "d": ["Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0022403", "l": "cell cycle phase", "d": ["One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000493", "l": "box H/ACA snoRNP assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0051666", "l": "actin cortical patch localization", "d": ["Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010815", "l": "bradykinin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010912", "l": "positive regulation of isomerase activity", "d": ["Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003414", "l": "chondrocyte morphogenesis involved in endochondral bone morphogenesis", "d": ["The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003355", "l": "cilium movement involved in otolith formation", "d": ["The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090027", "l": "negative regulation of monocyte chemotaxis", "d": ["Any process that decreases the frequency, rate, or extent of monocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904896", "l": "ESCRT complex disassembly", "d": ["The disaggregation of an ESCRT complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034959", "l": "endothelin maturation", "d": ["The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061127", "l": "negative regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904177", "l": "regulation of adipose tissue development", "d": ["Any process that modulates the frequency, rate or extent of adipose tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0050810", "l": "regulation of steroid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904933", "l": "regulation of cell proliferation in midbrain", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation in midbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.594648570918388", "identifiers": [{"i": "GO:0009057", "l": "macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905442", "l": "cellular response to chondroitin 4'-sulfate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0044000", "l": "movement in host", "d": ["The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018963", "l": "phthalate metabolic process", "d": ["The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042884", "l": "microcin transport", "d": ["The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032811", "l": "negative regulation of epinephrine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009708", "l": "benzyl isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000561", "l": "regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140026", "l": "contractile vacuole dissociation from plasma membrane", "d": ["The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000365", "l": "mRNA trans splicing, via spliceosome", "d": ["The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902025", "l": "nitrate import", "d": ["The directed movement of nitrate into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060324", "l": "face development", "d": ["The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003264", "l": "regulation of cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061718", "l": "glucose catabolic process to pyruvate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034585", "l": "21U-RNA metabolic process", "d": ["The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.773643206414697", "identifiers": [{"i": "GO:0001816", "l": "cytokine production", "d": ["The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015881", "l": "creatine transmembrane transport", "d": ["The directed movement of creatine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009202", "l": "deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904557", "l": "L-alanine transmembrane transport", "d": ["The directed movement of L-alanine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140724", "l": "positive regulation of patulin biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of patulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904755", "l": "regulation of gut granule assembly", "d": ["Any process that modulates the frequency, rate or extent of gut granule assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010254", "l": "nectary development", "d": ["The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034222", "l": "regulation of cell wall chitin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042118", "l": "endothelial cell activation", "d": ["The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150129", "l": "positive regulation of interleukin-33 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-33 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018972", "l": "toluene-4-sulfonate metabolic process", "d": ["The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0150115", "l": "cell-substrate junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0008088", "l": "axo-dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in neuron projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0038009", "l": "regulation of signal transduction by receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140231", "l": "anterograde axonal transport of neurotransmitter receptor complex", "d": ["The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.284682648756693", "identifiers": [{"i": "GO:0016052", "l": "carbohydrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035728", "l": "response to hepatocyte growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme 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{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000262", "l": "positive regulation of blood coagulation, common pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904521", "l": "negative regulation of myofibroblast cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003388", "l": "neuron development involved in amphid sensory organ development", "d": ["The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901101", "l": "gramicidin S metabolic process", "d": ["The chemical reactions and pathways involving gramicidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075031", "l": "positive regulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0043369", "l": "CD4-positive or CD8-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018182", "l": "protein-heme linkage via 3'-L-histidine", "d": ["The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0030856", "l": "regulation of epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046132", "l": "pyrimidine ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0044560", "l": "envenomation resulting in modulation of ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904779", "l": "regulation of protein localization to centrosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.109627871289504", "identifiers": [{"i": "GO:0007423", "l": "sensory organ development", "d": ["The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044580", "l": "butyryl-CoA catabolic process", "d": ["The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1901804", "l": "beta-glucoside metabolic process", "d": ["The chemical reactions and 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["Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000479", "l": "regulation of cAMP-dependent protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062028", "l": "regulation of stress granule assembly", "d": ["Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032903", "l": "regulation of nerve growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of nerve growth 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A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060509", "l": "type I pneumocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. 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They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032718", "l": "negative regulation of interleukin-9 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000431", "l": "regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0045824", "l": "negative regulation of innate immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900605", "l": "tensidol A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol A."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031529", "l": "ruffle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015771", "l": "trehalose transport", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000512", "l": "negative regulation of granzyme A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019255", "l": "glucose 1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060753", "l": "regulation of mast cell chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141065", "l": "maternal mRNA clearance", "d": ["The chemical reactions and pathways resulting in the clearance of maternal mRNA transcripts from the zygote as part of the maternal-to-zygote transition in gene expression."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990789", "l": "thyroid gland epithelial cell proliferation", "d": ["The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046236", "l": "mandelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901893", "l": "positive regulation of cell septum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cell septum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002322", "l": "B cell proliferation involved in immune response", "d": ["The expansion of a B cell population by cell division following B cell activation during an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098933", "l": "disruption by symbiont of host cell envelope", "d": ["The process by which a symbiont breaks down the cell wall of its host. 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The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904684", "l": "negative regulation of metalloendopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901942", "l": "(+)-epi-alpha-bisabolol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140568", "l": "extraction of mislocalized protein from membrane", "d": ["The removal of a mislocalized protein from a cellular membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903963", "l": "arachidonate transport", "d": ["The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.598893201489091", "identifiers": [{"i": "GO:0070887", "l": "cellular response to chemical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001157", "l": "negative regulation of proline catabolic process to glutamate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010613", "l": "positive regulation of cardiac muscle hypertrophy", "d": ["Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016080", "l": "synaptic vesicle targeting", "d": ["The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019636", "l": "phosphonoacetate metabolic process", "d": ["The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042207", "l": "styrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045063", "l": "T-helper 1 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090280", "l": "positive regulation of calcium ion import", "d": ["Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021521", "l": "ventral spinal cord interneuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019285", "l": "glycine betaine biosynthetic process from choline", "d": ["The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009947", "l": "centrolateral axis specification", "d": ["The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0031579", "l": "membrane raft organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.49789709104158", "identifiers": [{"i": "GO:0043588", "l": "skin development", "d": ["The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045476", "l": "nurse cell apoptotic process", "d": ["Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007339", "l": "binding of sperm to zona pellucida", "d": ["The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:2000514", "l": "regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030187", "l": "melatonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902747", "l": "negative regulation of lens fiber cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010080", "l": "regulation of floral meristem growth", "d": ["Any process involved in maintaining the size and shape of a floral meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010150", "l": "leaf senescence", "d": ["The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902322", "l": "regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019329", "l": "ammonia oxidation", "d": ["The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.910117462442862", "identifiers": [{"i": "GO:0007017", "l": "microtubule-based process", "d": ["Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035694", "l": "mitochondrial protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071359", "l": "cellular response to dsRNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106023", "l": "regulation of pupariation", "d": ["Any process that modulates the onset of pupariation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075285", "l": "sexual sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039699", "l": "viral mRNA cap methylation", "d": ["An innate immune response evasion mechanism in which a virus methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140576", "l": "ascorbate homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903558", "l": "3-cyano-L-alanine metabolic process", "d": ["The chemical reactions and pathways involving 3-cyano-L-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046010", "l": "positive regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070536", "l": "protein K63-linked deubiquitination", "d": ["A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070202", "l": "regulation of establishment of protein localization to chromosome", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905678", "l": "negative regulation of adaptive immune effector response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042873", "l": "aldonate transmembrane transport", "d": ["The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.782924002860781", "identifiers": [{"i": "GO:0044036", "l": "cell wall macromolecule metabolic process", "d": ["The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. 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It is a common intermediate in phospholipid biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0022018", "l": "lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902138", "l": "(-)-secoisolariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901132", "l": "kanamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of kanamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0018202", "l": "peptidyl-histidine modification", "d": ["The modification of peptidyl-histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0009072", "l": "aromatic amino acid metabolic process", "d": ["The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033330", "l": "kaempferol O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905272", "l": "negative regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072382", "l": "minus-end-directed vesicle transport along microtubule", "d": ["The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900600", "l": "endocrocin metabolic process", "d": ["The chemical reactions and pathways involving endocrocin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009244", "l": "lipopolysaccharide core region biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035532", "l": "negative regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140051", "l": "positive regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061266", "l": "mesonephric interstitial fibroblast differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016046", "l": "detection of fungus", "d": ["The series of events in which a stimulus from a fungus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009854", "l": "oxidative photosynthetic carbon pathway", "d": ["The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046813", "l": "receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900459", "l": "positive regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075032", "l": "negative regulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001970", "l": "positive regulation of activation of membrane attack complex", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901755", "l": "vitamin D3 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin D3."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.276496379637869", "identifiers": [{"i": "GO:1901698", "l": "response to nitrogen compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905383", "l": "protein localization to presynapse", "d": ["A process in which a protein is transported to, or maintained in, a location within a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000834", "l": "regulation of androgen secretion", "d": ["Any process that modulates the frequency, rate or extent of androgen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045141", "l": "meiotic telomere clustering", "d": ["The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002716", "l": "negative regulation of natural killer cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010071", "l": "root meristem specification", "d": ["The specification of a meristem which will give rise to a primary or lateral root."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032108", "l": "negative regulation of response to nutrient levels", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000169", "l": "regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019508", "l": "2,5-dihydroxypyridine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046251", "l": "limonene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070480", "l": "exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048613", "l": "embryonic ectodermal digestive tract morphogenesis", "d": ["The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080143", "l": "regulation of amino acid export", "d": ["Any process that modulates the frequency, rate or extent of amino acid export. 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Molybdate is the bivalent anion derived from molybdic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007523", "l": "larval visceral muscle development", "d": ["The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002257", "l": "negative regulation of kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0110030", "l": "regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050980", "l": "detection of light stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002609", "l": "positive regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045975", "l": "positive regulation of translation, ncRNA-mediated", "d": ["Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016189", "l": "synaptic vesicle to endosome fusion", "d": ["Fusion of a synaptic vesicle with an endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097360", "l": "chorionic trophoblast cell proliferation", "d": ["The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0000749", "l": "response to pheromone triggering conjugation with cellular fusion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903864", "l": "P granule disassembly", "d": ["The disaggregation of a P granule into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904997", "l": "regulation of leukocyte adhesion to arterial endothelial cell", "d": ["Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036492", "l": "eiF2alpha phosphorylation in response to endoplasmic reticulum stress", "d": ["The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097083", "l": "vascular associated smooth muscle cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901402", "l": "negative regulation of tetrapyrrole metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140570", "l": "extraction of mislocalized protein from mitochondrial outer membrane", "d": ["The removal of a mislocalized protein from the mitochondrial outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048936", "l": "peripheral nervous system neuron axonogenesis", "d": ["Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0050885", "l": "neuromuscular process controlling balance", "d": ["Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1900426", "l": "positive regulation of defense response to bacterium", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097615", "l": "modulation by host of symbiont type IV pilus-dependent motility", "d": ["The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097436", "l": "entry into dormancy", "d": ["The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032493", "l": "response to bacterial lipoprotein", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003023", "l": "baroreceptor detection of increased arterial stretch", "d": ["The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.833128032771839", "identifiers": [{"i": "GO:0007631", "l": "feeding behavior", "d": ["Behavior associated with the intake of food."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901742", "l": "2-deoxystreptamine metabolic process", "d": ["The chemical reactions and pathways involving 2-deoxystreptamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090639", "l": "phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol", "d": ["The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0006305", "l": "DNA alkylation", "d": ["The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.03673969480753", "identifiers": [{"i": "GO:0051046", "l": "regulation of secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048759", "l": "xylem vessel member cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009589", "l": "detection of UV", "d": ["The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905662", "l": "negative regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098942", "l": "retrograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097548", "l": "seed abscission", "d": ["The controlled shedding of a seed."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0048545", "l": "response to steroid hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0032606", "l": "type I interferon production", "d": ["The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099010", "l": "modification of postsynaptic structure", "d": ["Any process that modifies the structure of a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048886", "l": "neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030211", "l": "heparin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0031139", "l": "positive regulation of conjugation with cellular fusion", "d": ["Any process that increases the rate or frequency of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902148", "l": "positive regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002381", "l": "immunoglobulin production involved in immunoglobulin-mediated immune response", "d": ["The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019467", "l": "ornithine catabolic process, by decarboxylation", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000937", "l": "negative regulation of cellotriose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002017", "l": "regulation of blood volume by renal aldosterone", "d": ["The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1902967", "l": "protein localization to mitotic spindle midzone", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018069", "l": "peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone", "d": ["The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061369", "l": "negative regulation of testicular blood vessel morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000410", "l": "carbon catabolite repression of transcription by galactose", "d": ["A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141024", "l": "adhesion of symbiont to host cell surface via host membrane carbohydrate", "d": ["The attachment of a symbiont to its host by binding to a carbohydrate on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080058", "l": "protein deglutathionylation", "d": ["The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035937", "l": "estrogen secretion", "d": ["The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901770", "l": "daunorubicin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of daunorubicin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010299", "l": "detoxification of cobalt ion", "d": ["Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002184", "l": "cytoplasmic translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042412", "l": "taurine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060792", "l": "sweat gland development", "d": ["The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072388", "l": "flavin adenine dinucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050493", "l": "GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904934", "l": "negative regulation of cell proliferation in midbrain", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042167", "l": "heme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000138", "l": "positive regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021788", "l": "chemoattraction of branchiomotor neuron axon in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001172", "l": "RNA-templated transcription", "d": ["The synthesis of an RNA transcript from an RNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018215", "l": "protein phosphopantetheinylation", "d": ["The modification of a protein amino acid by phosphopantetheinylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060167", "l": "regulation of adenosine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060029", "l": "convergent extension involved in organogenesis", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001186", "l": "negative regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905823", "l": "negative regulation of mitotic sister chromatid arm separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071107", "l": "response to parathyroid hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070598", "l": "cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046093", "l": "deoxycytidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032121", "l": "meiotic attachment of telomeric heterochromatin to spindle pole body", "d": ["The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0043101", "l": "purine-containing compound salvage", "d": ["Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042722", "l": "alpha-beta T cell activation by superantigen", "d": ["The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0051231", "l": "spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0101017", "l": "regulation of mitotic DNA replication initiation from late origin", "d": ["Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010905", "l": "negative regulation of UDP-glucose catabolic process", "d": ["Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140493", "l": "very long-chain fatty acid beta-oxidation", "d": ["A fatty acid beta-oxidation pathway acting on a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051591", "l": "response to cAMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905304", "l": "regulation of cardiac myofibril assembly", "d": ["Any process that modulates the frequency, rate or extent of cardiac myofibril assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045874", "l": "positive regulation of sevenless signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044480", "l": "envenomation resulting in positive regulation of mast cell degranulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018951", "l": "p-xylene metabolic process", "d": ["The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0060795", "l": "cell fate commitment involved in formation of primary germ layer", "d": ["The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021980", "l": "subpallium cell migration", "d": ["The orderly movement of cells from one site to another in the subpallium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000928", "l": "negative regulation of cellodextrin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019407", "l": "hexitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905139", "l": "apical ectodermal ridge formation", "d": ["The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071874", "l": "cellular response to norepinephrine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1905063", "l": "regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032719", "l": "negative regulation of TRAIL production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034251", "l": "regulation of amide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901207", "l": "regulation of heart looping", "d": ["Any process that modulates the frequency, rate or extent of heart looping."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009208", "l": "pyrimidine ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097171", "l": "ADP-L-glycero-beta-D-manno-heptose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905244", "l": "regulation of modification of synaptic structure", "d": ["Any process that modulates the frequency, rate or extent of modification of synaptic structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904760", "l": "regulation of myofibroblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046321", "l": "positive regulation of fatty acid oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040010", "l": "positive regulation of growth rate", "d": ["Any process that increases the rate of growth of all or part of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042949", "l": "arbutin transport", "d": ["The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0051147", "l": "regulation of muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900308", "l": "positive regulation of maltoheptaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltoheptaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0032309", "l": "icosanoid secretion", "d": ["The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014822", "l": "detection of wounding", "d": ["The series of events by which an injury stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032847", "l": "regulation of cellular pH reduction", "d": ["Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904383", "l": "response to sodium phosphate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0034599", "l": "cellular response to oxidative stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002862", "l": "negative regulation of inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032353", "l": "negative regulation of hormone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0000045", "l": "autophagosome assembly", "d": ["The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044634", "l": "negative regulation of complement activation, alternative pathway in another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120162", "l": "positive regulation of cold-induced thermogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903028", "l": "positive regulation of opsonization", "d": ["Any process that activates or increases the frequency, rate or extent of opsonization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002671", "l": "negative regulation of B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032336", "l": "negative regulation of activin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0034285", "l": "response to disaccharide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070100", "l": "negative regulation of chemokine-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0031334", "l": "positive regulation of protein-containing complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007304", "l": "chorion-containing eggshell formation", "d": ["The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150013", "l": "negative regulation of neuron projection arborization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046137", "l": "negative regulation of vitamin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900652", "l": "regulation of demethylkotanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006626", "l": "protein targeting to mitochondrion", "d": ["The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031025", "l": "equatorial microtubule organizing center disassembly", "d": ["The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021656", "l": "rhombomere 2 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901507", "l": "negative regulation of acylglycerol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900590", "l": "violaceol I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of violaceol I."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061577", "l": "calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901201", "l": "regulation of extracellular matrix assembly", "d": ["Any process that modulates the frequency, rate or extent of extracellular matrix assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901371", "l": "regulation of leaf morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of leaf morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000970", "l": "tRNA exon ligation utilizing GTP as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072150", "l": "juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044637", "l": "envenomation resulting in negative regulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0042551", "l": "neuron maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0005978", "l": "glycogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061181", "l": "regulation of chondrocyte development", "d": ["Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904942", "l": "regulation of cardiac ventricle formation", "d": ["Any process that modulates the frequency, rate or extent of cardiac ventricle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060346", "l": "bone trabecula formation", "d": ["The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048457", "l": "floral whorl morphogenesis", "d": ["The process in which the anatomical structures of the floral whorl are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140967", "l": "manganese import into cell", "d": ["The directed movement of mangnanese ions from outside of a cell into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043571", "l": "maintenance of CRISPR repeat elements", "d": ["Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0001941", "l": "postsynaptic membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0140271", "l": "hexose import across plasma membrane", "d": ["The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010910", "l": "positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000611", "l": "positive regulation of thyroid hormone generation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid hormone generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003134", "l": "endodermal-mesodermal cell signaling involved in heart induction", "d": ["Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902857", "l": "positive regulation of non-motile cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042748", "l": "circadian sleep/wake cycle, non-REM sleep", "d": ["All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0050981", "l": "detection of electrical stimulus", "d": ["The series of events by which an electrical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0044379", "l": "protein localization to actin cortical patch", "d": ["A process in which a protein is transported to, or maintained in, an actin cortical patch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001190", "l": "positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0021695", "l": "cerebellar cortex development", "d": ["The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905258", "l": "regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0045761", "l": "regulation of adenylate cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905827", "l": "positive regulation of selenocysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015938", "l": "coenzyme A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000410", "l": "regulation of thymocyte migration", "d": ["Any process that modulates the frequency, rate or extent of thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042668", "l": "auditory receptor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0052802", "l": "nitroimidazole metabolic process", "d": ["The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000546", "l": "positive regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1900542", "l": "regulation of purine nucleotide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902357", "l": "2-isopropylmalate(2-) transmembrane transport", "d": ["The process in which 2-isopropylmalate(2-) is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032303", "l": "regulation of icosanoid secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903003", "l": "positive regulation of protein deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035164", "l": "embryonic plasmatocyte differentiation", "d": ["The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0051603", "l": "proteolysis involved in protein catabolic process", "d": ["The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0036376", "l": "sodium ion export across plasma membrane", "d": ["The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901304", "l": "regulation of spermidine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of spermidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0030041", "l": "actin filament polymerization", "d": ["Assembly of actin filaments by the addition of actin monomers to a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061979", "l": "femoral head articular cartilage development", "d": ["The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061380", "l": "superior colliculus development", "d": ["The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090350", "l": "negative regulation of cellular organofluorine metabolic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009098", "l": "leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045873", "l": "negative regulation of sevenless signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061782", "l": "vesicle fusion with vesicle", "d": ["Fusion of the membrane of a transport vesicle with a target membrane on another vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032516", "l": "positive regulation of phosphoprotein phosphatase activity", "d": ["Any process that activates or increases the activity of a phosphoprotein phosphatase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061406", "l": "positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140501", "l": "positive regulation of reticulophagy", "d": ["Any process that increases the frequency, rate or extent of reticulophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120264", "l": "regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904636", "l": "response to ionomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904394", "l": "negative regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0035914", "l": "skeletal muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900560", "l": "austinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of austinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032763", "l": "regulation of mast cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of mast cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010826", "l": "negative regulation of centrosome duplication", "d": ["Any process that decreases the frequency, rate or extent of centrosome duplication. 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Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036073", "l": "perichondral ossification", "d": ["Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045940", "l": "positive regulation of steroid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071246", "l": "cellular response to chlorate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0051149", "l": "positive regulation of muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002123", "l": "irritable aggressive behavior", "d": ["Aggressive behavior induced by frustration and directed against an available target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006781", "l": "succinyl-CoA pathway", "d": ["The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000292", "l": "regulation of defecation", "d": ["Any process that modulates the frequency, rate or extent of defecation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015936", "l": "coenzyme A metabolic process", "d": ["The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0001676", "l": "long-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0032351", "l": "negative regulation of hormone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006750", "l": "glutathione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016348", "l": "imaginal disc-derived leg joint morphogenesis", "d": ["The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.388382942757389", "identifiers": [{"i": "GO:0045453", "l": "bone resorption", "d": ["The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035319", "l": "imaginal disc-derived wing hair elongation", "d": ["Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010865", "l": "stipule development", "d": ["The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032725", "l": "positive regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033482", "l": "D-galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070396", "l": "lipoteichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006196", "l": "AMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902811", "l": "positive regulation of skeletal muscle fiber differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036058", "l": "filtration diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090355", "l": "positive regulation of auxin metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075511", "l": "macropinosome lysis involved in viral entry into host cell", "d": ["Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019662", "l": "non-glycolytic fermentation", "d": ["Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.339867169364453", "identifiers": [{"i": "GO:0006400", "l": "tRNA modification", "d": ["The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900646", "l": "regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903525", "l": "regulation of membrane tubulation", "d": ["Any process that modulates the frequency, rate or extent of membrane tubulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0006903", "l": "vesicle targeting", "d": ["The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000159", "l": "regulation of planar cell polarity pathway involved in heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900218", "l": "negative regulation of apoptotic process involved in metanephric nephron tubule development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106012", "l": "positive regulation of protein localization to medial cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.576410689076511", "identifiers": [{"i": "GO:0090304", "l": "nucleic acid metabolic process", "d": ["Any cellular metabolic process involving nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900820", "l": "orlandin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of orlandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140122", "l": "regulation of Lewy body formation", "d": ["Any process that modulates the frequency, rate or extent of Lewy body formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062229", "l": "regulation of larval somatic muscle development", "d": ["Any process that modulates the rate, frequency or extent of larval somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042894", "l": "fosmidomycin transport", "d": ["The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901423", "l": "response to benzene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019626", "l": "short-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072223", "l": "metanephric glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903394", "l": "protein localization to kinetochore involved in kinetochore assembly", "d": ["Any protein localization to kinetochore that is involved in kinetochore assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0043555", "l": "regulation of translation in response to stress", "d": ["Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003295", "l": "cell proliferation involved in atrial ventricular junction remodeling", "d": ["The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019444", "l": "tryptophan catabolic process to catechol", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071730", "l": "beak formation", "d": ["The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0048839", "l": "inner ear development", "d": ["The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003131", "l": "mesodermal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information from mesodermal cells to endodermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990058", "l": "fruit replum development", "d": ["The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0021885", "l": "forebrain cell migration", "d": ["The orderly movement of a cell from one site to another at least one of which is located in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000415", "l": "positive regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000334", "l": "positive regulation of blood microparticle formation", "d": ["Any process that activates or increases the frequency, rate or extent of blood microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009396", "l": "folic acid-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid and its derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048921", "l": "posterior lateral line neuromast cupula development", "d": ["The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900336", "l": "regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900152", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.561493752554874", "identifiers": [{"i": "GO:0006260", "l": "DNA replication", "d": ["The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031551", "l": "regulation of brain-derived neurotrophic factor-activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045049", "l": "protein insertion into ER membrane by N-terminal cleaved signal sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007440", "l": "foregut morphogenesis", "d": ["The process in which the anatomical structures of the foregut are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0048858", "l": "cell projection morphogenesis", "d": ["The process in which the anatomical structures of a cell projection are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044602", "l": "protein deadenylylation", "d": ["The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043001", "l": "Golgi to plasma membrane protein transport", "d": ["The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0071216", "l": "cellular response to biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060937", "l": "cardiac fibroblast cell fate commitment", "d": ["The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060939", "l": "epicardium-derived cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044245", "l": "polysaccharide digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046450", "l": "dethiobiotin metabolic process", "d": ["The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039011", "l": "pronephric proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031555", "l": "transcriptional attenuation", "d": ["A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900370", "l": "positive regulation of post-transcriptional gene silencing by RNA", "d": ["Any process that activates or increases the frequency, rate or extent of post-transcriptional gene silencing by RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035622", "l": "intrahepatic bile duct development", "d": ["The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006050", "l": "mannosamine metabolic process", "d": ["The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034659", "l": "isopropylmalate transport", "d": ["The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0089718", "l": "amino acid import across plasma membrane", "d": ["The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070377", "l": "negative regulation of ERK5 cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001008", "l": "positive regulation of cellulose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018417", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide", "d": ["The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0001701", "l": "in utero embryonic development", "d": ["The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071390", "l": "cellular response to ecdysone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0070918", "l": "regulatory ncRNA processing", "d": ["A process leading to the generation of a functional regulatory non-coding RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000481", "l": "maturation of 5S rRNA", "d": ["Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016560", "l": "protein import into peroxisome matrix, docking", "d": ["The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0075733", "l": "intracellular transport of virus", "d": ["The directed movement of a virus, or part of a virus, within the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045501", "l": "regulation of sevenless signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the sevenless signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045463", "l": "R8 cell development", "d": ["The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007480", "l": "imaginal disc-derived leg morphogenesis", "d": ["The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050969", "l": "detection of chemical stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0043500", "l": "muscle adaptation", "d": ["A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0002673", "l": "regulation of acute inflammatory response", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900359", "l": "positive regulation of nigerotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of nigerotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090185", "l": "negative regulation of kidney development", "d": ["Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902336", "l": "positive regulation of retinal ganglion cell axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000870", "l": "regulation of progesterone secretion", "d": ["Any process that modulates the frequency, rate or extent of progesterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044571", "l": "[2Fe-2S] cluster assembly", "d": ["The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040033", "l": "sRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904616", "l": "regulation of actin binding", "d": ["Any process that modulates the frequency, rate or extent of actin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905812", "l": "regulation of motor neuron axon guidance", "d": ["Any process that modulates the frequency, rate or extent of motor neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032498", "l": "detection of muramyl dipeptide", "d": ["The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140039", "l": "cell-cell adhesion in response to extracellular stimulus", "d": ["The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150052", "l": "regulation of postsynapse assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097061", "l": "dendritic spine organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000273", "l": "positive regulation of signaling receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of signaling receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903346", "l": "positive regulation of protein polyglycylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyglycylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0000921", "l": "septin ring assembly", "d": ["The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098775", "l": "curli assembly", "d": ["The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002125", "l": "maternal aggressive behavior", "d": ["Aggressive behavior of a female to protect her offspring from a threat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009050", "l": "glycopeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900285", "l": "regulation of cellotriose transport", "d": ["Any process that modulates the frequency, rate or extent of cellotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:2000104", "l": "negative regulation of DNA-templated DNA replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150054", "l": "regulation of postsynaptic neurotransmitter receptor diffusion trapping", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0090715", "l": "immunological memory formation process", "d": ["Any immunological memory process that can contribute to the formation of immunological memory."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0043111", "l": "replication fork arrest", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018926", "l": "methanesulfonic acid metabolic process", "d": ["The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0045944", "l": "positive regulation of transcription by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905839", "l": "negative regulation of telomeric D-loop disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039564", "l": "disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051490", "l": "negative regulation of filopodium assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098510", "l": "sensory perception of high humidity", "d": ["The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048378", "l": "regulation of lateral mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905492", "l": "positive regulation of branching morphogenesis of a nerve", "d": ["Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060142", "l": "regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0042475", "l": "odontogenesis of dentin-containing tooth", "d": ["The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060458", "l": "right lung development", "d": ["The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.920120576733368", "identifiers": [{"i": "GO:0031328", "l": "positive regulation of cellular biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043252", "l": "sodium-independent organic anion transport", "d": ["The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035054", "l": "embryonic heart tube anterior/posterior pattern specification", "d": ["The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0070296", "l": "sarcoplasmic reticulum calcium ion transport", "d": ["The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018068", "l": "peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine", "d": ["The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0022616", "l": "DNA strand elongation", "d": ["The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003228", "l": "atrial cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042317", "l": "penicillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1905132", "l": "regulation of meiotic chromosome separation", "d": ["Any process that modulates the frequency, rate or extent of meiotic chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904309", "l": "response to cordycepin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901010", "l": "(S)-reticuline metabolic process", "d": ["The chemical reactions and pathways involving (S)-reticuline."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060505", "l": "epithelial cell proliferation involved in lung bud dilation", "d": ["The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003329", "l": "pancreatic PP cell fate commitment", "d": ["The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060557", "l": "positive regulation of vitamin D biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044830", "l": "modulation by host of viral RNA genome replication", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060353", "l": "regulation of cell adhesion molecule production", "d": ["Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039697", "l": "negative stranded viral RNA transcription", "d": ["A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018021", "l": "peptidyl-histidine methylation", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903224", "l": "regulation of endodermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of endodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000224", "l": "regulation of testosterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of testosterone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900904", "l": "positive regulation of hexadecanal biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0098724", "l": "symmetric stem cell division", "d": ["Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000827", "l": "mitochondrial RNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045722", "l": "positive regulation of gluconeogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gluconeogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900273", "l": "positive regulation of long-term synaptic potentiation", "d": ["Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1902022", "l": "L-lysine transport", "d": ["The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018115", "l": "peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062133", "l": "negative regulation of L-glutamine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0036301", "l": "macrophage colony-stimulating factor production", "d": ["The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.511465329959393", "identifiers": [{"i": "GO:0050865", "l": "regulation of cell activation", "d": ["Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055060", "l": "asymmetric neuroblast division resulting in ganglion mother cell formation", "d": ["Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006354", "l": "DNA-templated transcription elongation", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900133", "l": "regulation of renin secretion into blood stream", "d": ["Any process that modulates the frequency, rate or extent of renin secretion into blood stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900902", "l": "regulation of hexadecanal biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071544", "l": "diphosphoinositol polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.718318631034926", "identifiers": [{"i": "GO:0008202", "l": "steroid metabolic process", "d": ["The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010543", "l": "regulation of platelet activation", "d": ["Any process that modulates the rate or frequency of platelet activation. 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Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0040009", "l": "regulation of growth rate", "d": ["Any process that modulates the rate of growth of all or part of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006600", "l": "creatine metabolic process", "d": ["The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0050963", "l": "detection of electrical stimulus involved in sensory perception", "d": ["The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043157", "l": "response to cation stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904418", "l": "regulation of telomeric loop formation", "d": ["Any process that modulates the frequency, rate or extent of telomeric loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060882", "l": "basement membrane disassembly involved in semicircular canal fusion", "d": ["A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044781", "l": "bacterial-type flagellum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900796", "l": "terrequinone A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terrequinone A."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:0050892", "l": "intestinal absorption", "d": ["Any process in which nutrients are taken up from the contents of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001024", "l": "negative regulation of response to drug", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0000768", "l": "syncytium formation by plasma membrane fusion", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030720", "l": "oocyte localization involved in germarium-derived egg chamber formation", "d": ["Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.361282203588587", "identifiers": [{"i": "GO:0104004", "l": "cellular response to environmental stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0051282", "l": "regulation of sequestering of calcium ion", "d": ["Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0071542", "l": "dopaminergic neuron differentiation", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0034113", "l": "heterotypic cell-cell adhesion", "d": ["The attachment of a cell to a cell of a different type via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032765", "l": "positive regulation of mast cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0002495", "l": "antigen processing and presentation of peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900005", "l": "positive regulation of serine-type endopeptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060036", "l": "notochord cell vacuolation", "d": ["The assembly and arrangement of a vacuole within a cell of the notochord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014008", "l": "positive regulation of microglia differentiation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090018", "l": "posterior neural plate formation", "d": ["The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006921", "l": "cellular component disassembly involved in execution phase of apoptosis", "d": ["The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0042742", "l": "defense response to bacterium", "d": ["Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002693", "l": "positive regulation of cellular extravasation", "d": ["Any process that activates or increases the frequency, rate, or extent of cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000591", "l": "positive regulation of metanephric mesenchymal cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000200", "l": "regulation of ribosomal subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120317", "l": "sperm mitochondrial sheath assembly", "d": ["The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070582", "l": "theta DNA replication", "d": ["A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072352", "l": "tricarboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0001523", "l": "retinoid metabolic process", "d": ["The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032258", "l": "cytoplasm to vacuole transport by the Cvt pathway", "d": ["A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045291", "l": "mRNA trans splicing, SL addition", "d": ["The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002664", "l": "regulation of T cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150032", "l": "positive regulation of protein localization to lysosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046622", "l": "positive regulation of organ growth", "d": ["Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106041", "l": "positive regulation of GABA-A receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031534", "l": "minus-end directed microtubule sliding", "d": ["The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070196", "l": "eukaryotic translation initiation factor 3 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042428", "l": "serotonin metabolic process", "d": ["The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019419", "l": "sulfate reduction", "d": ["The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038018", "l": "Wnt receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1903665", "l": "negative regulation of asexual reproduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0051090", "l": "regulation of DNA-binding transcription factor activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110088", "l": "hippocampal neuron apoptotic process", "d": ["Any apoptotic process that occurs in a hippocampal neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003117", "l": "regulation of vasoconstriction by circulating norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001117", "l": "protein-DNA-RNA complex disassembly", "d": ["The disaggregation of a protein-DNA-RNA complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043435", "l": "response to corticotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097097", "l": "nasal suture morphogenesis", "d": ["The process in which the nasal suture is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903977", "l": "positive regulation of glial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016107", "l": "sesquiterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904224", "l": "negative regulation of glucuronosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090680", "l": "viral release via disruption of host outer membrane", "d": ["The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902448", "l": "positive regulation of shade avoidance", "d": ["Any process that activates or increases the frequency, rate or extent of shade avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090431", "l": "alkyl caffeate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045958", "l": "positive regulation of complement activation, alternative pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043105", "l": "negative regulation of GTP cyclohydrolase I activity", "d": ["Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.831061310706126", "identifiers": [{"i": "GO:1901135", "l": "carbohydrate derivative metabolic process", "d": ["The chemical reactions and pathways involving carbohydrate derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0106106", "l": "cold-induced thermogenesis", "d": ["The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010748", "l": "negative regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048710", "l": "regulation of astrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of astrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003144", "l": "embryonic heart tube formation", "d": ["The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051257", "l": "meiotic spindle midzone assembly", "d": ["The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904686", "l": "regulation of mitotic spindle disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:1900673", "l": "olefin metabolic process", "d": ["The chemical reactions and pathways involving olefin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061518", "l": "microglial cell proliferation", "d": ["The expansion of a microglial cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050986", "l": "isopeptide cross-linking via N-(L-isoglutamyl)-glycine", "d": ["The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0006497", "l": "protein lipidation", "d": ["The covalent attachment of lipid groups to an amino acid in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061857", "l": "endoplasmic reticulum stress-induced pre-emptive quality control", "d": ["The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099627", "l": "neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033564", "l": "anterior/posterior axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0034369", "l": "plasma lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035621", "l": "ER to Golgi ceramide transport", "d": ["The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021644", "l": "vagus nerve morphogenesis", "d": ["The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000809", "l": "positive regulation of synaptic vesicle clustering", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0071444", "l": "cellular response to pheromone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031141", "l": "induction of conjugation upon carbon starvation", "d": ["The process in which a cell initiates conjugation with cellular fusion upon carbon starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031442", "l": "positive regulation of mRNA 3'-end processing", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001118", "l": "tetrahydromethanopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032510", "l": "endosome to lysosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044617", "l": "modulation of relaxation of smooth muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of smooth muscle in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046097", "l": "deoxyuridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051414", "l": "response to cortisol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902758", "l": "bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042062", "l": "long-term strengthening of neuromuscular junction", "d": ["Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035572", "l": "N-terminal peptidyl-serine dimethylation", "d": ["The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902996", "l": "regulation of neurofibrillary tangle assembly", "d": ["Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060786", "l": "regulation of cell differentiation involved in tissue homeostasis", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002481", "l": "antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904527", "l": "negative regulation of microtubule binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048026", "l": "positive regulation of mRNA splicing, via spliceosome", "d": ["Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900931", "l": "positive regulation of L-tyrosine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061972", "l": "dermal bone morphogenesis", "d": ["The process in which bone which forms superficially in the organism are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.295391821436155", "identifiers": [{"i": "GO:0002684", "l": "positive regulation of immune system process", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune system process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060031", "l": "mediolateral intercalation", "d": ["The interdigitation of cells along the mediolateral axis during gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902209", "l": "negative regulation of bacterial-type flagellum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043215", "l": "daunorubicin transport", "d": ["The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.16494433675436", "identifiers": [{"i": "GO:0002819", "l": "regulation of adaptive immune response", "d": ["Any process that modulates the frequency, rate, or extent of an adaptive immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0010958", "l": "regulation of amino acid import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of amino acid import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046886", "l": "positive regulation of hormone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0033555", "l": "multicellular organismal response to stress", "d": ["Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120258", "l": "peptidyl-threonine O-acetylation", "d": ["The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051760", "l": "meiotic sister chromatid cohesion, arms", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072721", "l": "cellular response to dithiothreitol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901455", "l": "negative regulation of response to toluene", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905957", "l": "regulation of cellular response to alcohol", "d": ["Any process that modulates the frequency, rate or extent of cellular response to alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150099", "l": "neuron-glial cell signaling", "d": ["Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051769", "l": "regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045117", "l": "azole transmembrane transport", "d": ["The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097590", "l": "archaeal-type flagellum-dependent cell motility", "d": ["Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021967", "l": "corticospinal neuron axon guidance through the cerebral cortex", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003181", "l": "atrioventricular valve morphogenesis", "d": ["The process in which the structure of the atrioventricular valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0099636", "l": "cytoplasmic streaming", "d": ["The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060125", "l": "negative regulation of growth hormone secretion", "d": ["Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901713", "l": "negative regulation of urea catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043567", "l": "regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055118", "l": "negative regulation of cardiac muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003394", "l": "cell adhesion involved in dendrite retrograde extension", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043041", "l": "amino acid activation for nonribosomal peptide biosynthetic process", "d": ["Activation of an amino acid for incorporation into a peptide by a nonribosomal process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903137", "l": "regulation of cell wall integrity MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000635", "l": "negative regulation of primary miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.20186355550635", "identifiers": [{"i": "GO:0120031", "l": "plasma membrane bounded cell projection assembly", "d": ["Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007057", "l": "spindle assembly involved in female meiosis I", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900171", "l": "positive regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071680", "l": "response to indole-3-methanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002358", "l": "B cell homeostatic proliferation", "d": ["The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0062009", "l": "secondary palate development", "d": ["The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. 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Their purpose is to receive, conduct, and transmit impulses in the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060023", "l": "soft palate development", "d": ["The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.735851798688778", "identifiers": [{"i": "GO:0014070", "l": "response to organic cyclic compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097009", "l": "energy homeostasis", "d": ["Any process involved in the balance between food intake (energy input) and energy expenditure."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902603", "l": "carnitine transmembrane transport", "d": ["The directed movement of carnitine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060061", "l": "Spemann organizer formation", "d": ["Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904733", "l": "negative regulation of electron transfer activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045598", "l": "regulation of fat cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of adipocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0002784", "l": "regulation of antimicrobial peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003068", "l": "regulation of systemic arterial blood pressure by acetylcholine", "d": ["The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902093", "l": "positive regulation of flagellated sperm motility", "d": ["Any process that activates or increases the frequency, rate or extent of flagellated sperm motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071770", "l": "DIM/DIP cell wall layer assembly", "d": ["The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060122", "l": "inner ear receptor cell stereocilium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000802", "l": "positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0006164", "l": "purine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044720", "l": "negative regulation of imaginal disc-derived wing size", "d": ["Any process that reduces the size of an imaginal disc-derived wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000672", "l": "negative regulation of motor neuron apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000742", "l": "regulation of anterior head development", "d": ["Any process that modulates the frequency, rate or extent of anterior head development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901596", "l": "response to reversine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061234", "l": "mesonephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902688", "l": "regulation of NAD metabolic process", "d": ["Any process that modulates the frequency, rate or extent of NAD metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042920", "l": "3-hydroxyphenylpropionic acid transmembrane transport", "d": ["The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000741", "l": "positive regulation of mesenchymal stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021567", "l": "rhombomere 1 development", "d": ["The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901373", "l": "lipid hydroperoxide transport", "d": ["The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070207", "l": "protein homotrimerization", "d": ["The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0007431", "l": "salivary gland development", "d": ["The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000527", "l": "regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099112", "l": "microtubule polymerization based protein transport", "d": ["The transport of a protein driven by polymerization of a microtubule to which it is attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002405", "l": "antigen sampling by dendritic cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902684", "l": "negative regulation of receptor localization to synapse", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901587", "l": "positive regulation of acid-sensing ion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000290", "l": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006313", "l": "DNA transposition", "d": ["A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0009555", "l": "pollen development", "d": ["The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002885", "l": "positive regulation of hypersensitivity", "d": ["Any process that activates or increases the frequency, rate, or extent of hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106057", "l": "negative regulation of calcineurin-mediated signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0051346", "l": "negative regulation of hydrolase activity", "d": ["Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0017158", "l": "regulation of calcium ion-dependent exocytosis", "d": ["Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000732", "l": "strand displacement", "d": ["The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002248", "l": "connective tissue replacement involved in inflammatory response wound healing", "d": ["The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared, as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0002921", "l": "negative regulation of humoral immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903476", "l": "protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006161", "l": "deoxyguanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015951", "l": "purine ribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901128", "l": "gentamycin metabolic process", "d": ["The chemical reactions and pathways involving gentamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044551", "l": "envenomation resulting in vasodilation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900642", "l": "positive regulation of austinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035399", "l": "helper T cell enhancement of B cell mediated immune response", "d": ["Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021672", "l": "rhombomere 7 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015743", "l": "malate transport", "d": ["The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048035", "l": "heme O catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044320", "l": "cellular response to leptin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007633", "l": "pattern orientation", "d": ["The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001080", "l": "nitrogen catabolite activation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001826", "l": "inner cell mass cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052104", "l": "induction by symbiont of host systemic acquired resistance", "d": ["Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001920", "l": "negative regulation of receptor recycling", "d": ["Any process that stops, prevents, or reduces the rate of receptor recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032605", "l": "hepatocyte growth factor production", "d": ["The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044241", "l": "lipid digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051965", "l": "positive regulation of synapse assembly", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048071", "l": "sex-specific pigmentation", "d": ["Establishment of a pattern of pigment in one sex that is not observed in the other sex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032603", "l": "fractalkine production", "d": ["The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120084", "l": "endothelial tip cell filopodium assembly", "d": ["The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034128", "l": "negative regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033138", "l": "positive regulation of peptidyl-serine phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900635", "l": "heptadecane metabolic process", "d": ["The chemical reactions and pathways involving heptadecane."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.519625387257847", "identifiers": [{"i": "GO:0022407", "l": "regulation of cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900500", "l": "regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0090646", "l": "mitochondrial tRNA processing", "d": ["The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0009166", "l": "nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060962", "l": "regulation of ribosomal protein gene transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071105", "l": "response to interleukin-11", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008208", "l": "C21-steroid hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039533", "l": "regulation of MDA-5 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904316", "l": "response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051823", "l": "regulation of synapse structural plasticity", "d": ["Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071765", "l": "nuclear inner membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902608", "l": "positive regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003292", "l": "cardiac septum cell differentiation", "d": ["The process in which an endocardial cushion cell becomes a cell of a cardiac septum."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901072", "l": "glucosamine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0007143", "l": "female meiotic nuclear division", "d": ["A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:1904748", "l": "regulation of apoptotic process involved in development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in development."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0033212", "l": "iron import into cell", "d": ["The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032063", "l": "negative regulation of translational initiation in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031860", "l": "telomeric 3' overhang formation", "d": ["The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014006", "l": "regulation of microglia differentiation", "d": ["Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071976", "l": "cell gliding", "d": ["Cell motility that results in the smooth movement of a cell along a solid surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061428", "l": "negative regulation of transcription from RNA polymerase II promoter in response to hypoxia", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042733", "l": "embryonic digit morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030514", "l": "negative regulation of BMP signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901752", "l": "leukotriene A4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene A4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900338", "l": "positive regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0120246", "l": "acetylenic compound metabolic process", "d": ["The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032713", "l": "negative regulation of interleukin-4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015747", "l": "urate transport", "d": ["The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903959", "l": "regulation of monoatomic anion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of anion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097359", "l": "UDP-glucosylation", "d": ["The covalent attachment of a UDP-glucose residue to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001788", "l": "antibody-dependent cellular cytotoxicity", "d": ["Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030240", "l": "skeletal muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002563", "l": "somatic diversification of immune receptors via alternate splicing", "d": ["The process in which immune receptor genes are diversified through alternate splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010651", "l": "negative regulation of cell communication by electrical coupling", "d": ["Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071304", "l": "cellular response to vitamin B6", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160007", "l": "glutathione import into mitochondrion", "d": ["The process in which glutathione is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901621", "l": "negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021611", "l": "facial nerve formation", "d": ["The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035752", "l": "lysosomal lumen pH elevation", "d": ["Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002675", "l": "positive regulation of acute inflammatory response", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006785", "l": "heme B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.119211224969447", "identifiers": [{"i": "GO:0098739", "l": "import across plasma membrane", "d": ["The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051755", "l": "meiotic sister chromatid arm separation", "d": ["The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902089", "l": "cell wall polysaccharide catabolic process involved in lateral root development", "d": ["Any cell wall polysaccharide catabolic process that is involved in lateral root 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exon sequences that all came from the same primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015942", "l": "formate metabolic process", "d": ["The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043201", "l": "response to leucine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031155", "l": "regulation of reproductive fruiting body development", "d": ["Any process that modulates the frequency, rate or extent of reproductive fruiting body development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015710", "l": "tellurite transport", "d": ["The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006668", "l": "sphinganine-1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043921", "l": "modulation by host of viral transcription", "d": ["Any process in which a host organism modulates the frequency, rate or extent of viral transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071028", "l": "nuclear mRNA surveillance", "d": ["A process that identifies and degrades defective or aberrant mRNAs within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140140", "l": "mitochondrial guanine nucleotide transmembrane transport", "d": ["The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0030857", "l": "negative regulation of epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002486", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0003348", "l": "cardiac endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008377", "l": "light-induced release of internally sequestered calcium ion", "d": ["The process in which the detection of light triggers the release of internally sequestered calcium ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0002446", "l": "neutrophil mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045717", "l": "negative regulation of fatty acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904484", "l": "cloacal gland development", "d": ["The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000087", "l": "regulation of mesonephric glomerulus development", "d": ["Any process that modulates the frequency, rate or extent of mesonephric glomerulus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.883171450034865", "identifiers": [{"i": "GO:0034502", "l": "protein localization to chromosome", "d": ["Any process in which a protein is transported to, or maintained at, a specific location on a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010642", "l": "negative regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046346", "l": "mannosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007639", "l": "homeostasis of number of meristem cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0033157", "l": "regulation of intracellular protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0006835", "l": "dicarboxylic acid transport", "d": ["The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036114", "l": "medium-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000923", "l": "positive regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903184", "l": "L-dopa metabolic process", "d": ["The chemical reactions and pathways involving L-dopa."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901000", "l": "regulation of response to salt stress", "d": ["Any process that modulates the frequency, rate or extent of response to salt stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006530", "l": "asparagine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035115", "l": "embryonic forelimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090540", "l": "bacterial cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900355", "l": "negative regulation of methanofuran metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002898", "l": "regulation of central B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of central B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902635", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042955", "l": "dextrin transport", "d": ["The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030516", "l": "regulation of axon extension", "d": ["Any process that modulates the rate, direction or extent of axon extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901925", "l": "negative regulation of protein import into nucleus during spindle assembly checkpoint", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0050994", "l": "regulation of lipid catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.539968465286577", "identifiers": [{"i": "GO:0045087", "l": "innate immune response", "d": ["Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035351", "l": "heme transmembrane transport", "d": ["The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043561", "l": "regulation of translational initiation in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000421", "l": "positive regulation of eosinophil extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000419", "l": "regulation of eosinophil extravasation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:1904950", "l": "negative regulation of establishment of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0042051", "l": "compound eye photoreceptor development", "d": ["The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905772", "l": "positive regulation of mesodermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070753", "l": "interleukin-35 production", "d": ["The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0061572", "l": "actin filament bundle organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904762", "l": "positive regulation of myofibroblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106154", "l": "perithecium formation", "d": ["The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006031", "l": "chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009961", "l": "response to 1-aminocyclopropane-1-carboxylic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035780", "l": "CD80 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072110", "l": "glomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070953", "l": "regulation of neutrophil mediated killing of fungus", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048315", "l": "conidium formation", "d": ["The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030723", "l": "ovarian fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021779", "l": "oligodendrocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048726", "l": "labrum development", "d": ["The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090292", "l": "nuclear matrix anchoring at nuclear membrane", "d": ["The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0043388", "l": "positive regulation of DNA binding", "d": ["Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0008360", "l": "regulation of cell shape", "d": ["Any process that modulates the surface configuration of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.145401758267646", "identifiers": [{"i": "GO:0060562", "l": "epithelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902995", "l": "positive regulation of phospholipid efflux", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid efflux."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014075", "l": "response to amine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033388", "l": "putrescine biosynthetic process from arginine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.494515853555001", "identifiers": [{"i": "GO:0019882", "l": "antigen processing and presentation", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.753431535235705", "identifiers": [{"i": "GO:0045165", "l": "cell fate commitment", "d": ["The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048914", "l": "myelination of anterior lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904261", "l": "positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903620", "l": "positive regulation of transdifferentiation", "d": ["Any process that activates or increases the frequency, rate or extent of transdifferentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014018", "l": "neuroblast fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903086", "l": "negative regulation of sinapate ester biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0006995", "l": "cellular response to nitrogen starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.284960350531655", "identifiers": [{"i": "GO:0050907", "l": "detection of chemical stimulus involved in sensory perception", "d": ["The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071465", "l": "cellular response to desiccation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1902404", "l": "mitotic actomyosin contractile ring contraction", "d": ["Any actomyosin contractile ring contraction that is involved in mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061502", "l": "early endosome to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061050", "l": "regulation of cell growth involved in cardiac muscle cell development", "d": ["Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072732", "l": "cellular response to calcium ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051628", "l": "positive regulation of epinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0021782", "l": "glial cell development", "d": ["The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002118", "l": "aggressive behavior", "d": ["A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006782", "l": "protoporphyrinogen IX biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904971", "l": "regulation of viral translation", "d": ["Any process that modulates the frequency, rate or extent of viral translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032728", "l": "positive regulation of interferon-beta production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-beta production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001946", "l": "lymphangiogenesis", "d": ["Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000357", "l": "negative regulation of kidney smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046834", "l": "lipid phosphorylation", "d": ["The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002104", "l": "endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071044", "l": "histone mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903219", "l": "negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031204", "l": "post-translational protein targeting to membrane, translocation", "d": ["The process in which a protein translocates through the ER membrane posttranslationally."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000473", "l": "maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036377", "l": "arbuscular mycorrhizal association", "d": ["A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0043144", "l": "sno(s)RNA processing", "d": ["Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071629", "l": "cytoplasm protein quality control by the ubiquitin-proteasome system", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990261", "l": "pre-mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0008333", "l": "endosome to lysosome transport", "d": ["The directed movement of substances from endosomes to lysosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150128", "l": "negative regulation of interleukin-33 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071653", "l": "negative regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010027", "l": "thylakoid membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030631", "l": "pyrrolysine incorporation", "d": ["The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090219", "l": "negative regulation of lipid kinase activity", "d": ["Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009216", "l": "purine deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035975", "l": "carbamoyl phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903960", "l": "negative regulation of anion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019536", "l": "vibriobactin metabolic process", "d": ["The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003127", "l": "detection of nodal flow", "d": ["The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060738", "l": "epithelial-mesenchymal signaling involved in prostate gland development", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071265", "l": "L-methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0061512", "l": "protein localization to cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070842", "l": "aggresome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051316", "l": "attachment of meiotic spindle microtubules to kinetochore", "d": ["The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905836", "l": "response to triterpenoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050496", "l": "peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine", "d": ["The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033245", "l": "negative regulation of penicillin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.652206388559449", "identifiers": [{"i": "GO:0001696", "l": "gastric acid secretion", "d": ["The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051486", "l": "isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901393", "l": "negative regulation of transforming growth factor beta1 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0019448", "l": "L-cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019606", "l": "2-oxobutyrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:1901577", "l": "regulation of alkane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of alkane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033368", "l": "protease localization to mast cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0035305", "l": "negative regulation of dephosphorylation", "d": ["Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032013", "l": "negative regulation of ARF protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.221914365702609", "identifiers": [{"i": "GO:0001838", "l": "embryonic epithelial tube formation", "d": ["The morphogenesis of an embryonic epithelium into a tube-shaped structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033670", "l": "regulation of NAD+ kinase activity", "d": ["Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060693", "l": "regulation of branching involved in salivary gland morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010074", "l": "maintenance of meristem identity", "d": ["The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046856", "l": "phosphatidylinositol dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphatidylinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901948", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003381", "l": "epithelial cell morphogenesis involved in gastrulation", "d": ["The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008592", "l": "regulation of Toll signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Tl signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0051169", "l": "nuclear transport", "d": ["The directed movement of substances into, out of, or within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000082", "l": "regulation of L-ascorbic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902130", "l": "(+)-lariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060975", "l": "cardioblast migration to the midline involved in heart field formation", "d": ["The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061475", "l": "cytosolic valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902852", "l": "regulation of nuclear migration during mitotic telophase", "d": ["Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070240", "l": "negative regulation of activated T cell autonomous cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042695", "l": "thelarche", "d": ["The beginning of development of the breasts in the female."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032742", "l": "positive regulation of interleukin-19 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-19 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903009", "l": "proteasome complex disassembly", "d": ["The disaggregation of a proteasome complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090693", "l": "plant organ senescence", "d": ["A plant organ developmental process during which a plant dismantles cellular components to reclaim the cellular building blocks and nutrients that have been deposited in the plant organs during growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061139", "l": "bud field specification", "d": ["The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.122742264235399", "identifiers": [{"i": "GO:0010628", "l": "positive regulation of gene expression", "d": ["Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099505", "l": "regulation of presynaptic membrane potential", "d": ["Any process that modulates the potential difference across a presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002750", "l": "antigen processing and presentation following macropinocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904982", "l": "sucrose transmembrane transport", "d": ["The process in which sucrose is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071381", "l": "cellular response to prostaglandin F stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019074", "l": "viral RNA genome packaging", "d": ["The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019495", "l": "proline catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032225", "l": "regulation of synaptic transmission, dopaminergic", "d": ["Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098962", "l": "regulation of postsynaptic neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070789", "l": "metula development", "d": ["The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018891", "l": "cyclohexanol metabolic process", "d": ["The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902422", "l": "hydrogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of H2 (dihydrogen)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051217", "l": "molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0031960", "l": "response to corticosteroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106091", "l": "glial cell projection elongation", "d": ["The process of creating an elongation or projection from a glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903124", "l": "negative regulation of thioredoxin peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904031", "l": "positive regulation of cyclin-dependent protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901162", "l": "primary amino compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of primary amino compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019632", "l": "shikimate metabolic process", "d": ["The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010146", "l": "fructan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0048229", "l": "gametophyte development", "d": ["The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.441195081532641", "identifiers": [{"i": "GO:0006900", "l": "vesicle budding from membrane", "d": ["The evagination of a membrane, resulting in formation of a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009794", "l": "regulation of mitotic cell cycle, embryonic", "d": ["Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0036314", "l": "response to sterol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000472", "l": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140329", "l": "lysophospholipid translocation", "d": ["The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000147", "l": "actin cortical patch assembly", "d": ["Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0033002", "l": "muscle cell proliferation", "d": ["The expansion of a muscle cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035942", "l": "dehydroepiandrosterone secretion", "d": ["The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010499", "l": "proteasomal ubiquitin-independent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904398", "l": "positive regulation of neuromuscular junction development", "d": ["Any process that activates or increases the frequency, rate or extent of neuromuscular junction development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900210", "l": "positive regulation of cardiolipin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0033015", "l": "tetrapyrrole catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901133", "l": "kanamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kanamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036291", "l": "protein cis-autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own amino acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.031705934574305", "identifiers": [{"i": "GO:0006766", "l": "vitamin metabolic process", "d": ["The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051036", "l": "regulation of endosome size", "d": ["Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075229", "l": "negative regulation of encysted zoospore germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0038011", "l": "negative regulation of signal transduction by receptor internalization", "d": ["Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060709", "l": "glycogen cell differentiation involved in embryonic placenta development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046891", "l": "peptidyl-cysteine S-carbamoylation", "d": ["The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903551", "l": "regulation of extracellular exosome assembly", "d": ["Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002296", "l": "T-helper 1 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0089707", "l": "L-lysine transmembrane export from vacuole", "d": ["The directed movement of L-lysine out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0060173", "l": "limb development", "d": ["The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021823", "l": "cerebral cortex tangential migration using cell-cell interactions", "d": ["The process in which neurons interact with each other to promote migration along a tangential plane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009162", "l": "deoxyribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018165", "l": "peptidyl-tyrosine uridylylation", "d": ["The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0007124", "l": "pseudohyphal growth", "d": ["The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150012", "l": "positive regulation of neuron projection arborization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048597", "l": "post-embryonic camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized during post-embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003138", "l": "primary heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0001583", "l": "detection of chemical stimulus involved in sensory perception of salty taste", "d": ["The series of events required for a salty taste stimulus to be received and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902323", "l": "negative regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070144", "l": "mitochondrial arginyl-tRNA aminoacylation", "d": ["The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018168", "l": "protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine", "d": ["The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0061208", "l": "cell differentiation involved in mesonephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0048467", "l": "gynoecium development", "d": ["The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015775", "l": "beta-glucan transport", "d": ["The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071980", "l": "cell surface adhesin-mediated gliding motility", "d": ["Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106304", "l": "mannogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902776", "l": "6-sulfoquinovose(1-) metabolic process", "d": ["The chemical reactions and pathways involving 6-sulfoquinovose(1-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140075", "l": "regulation of lipoprotein transport", "d": ["Any process that controls lipoprotein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044737", "l": "modulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030888", "l": "regulation of B cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0009404", "l": "toxin metabolic process", "d": ["The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003433", "l": "chondrocyte development involved in endochondral bone morphogenesis", "d": ["The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044522", "l": "envenomation resulting in myocyte killing in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001110", "l": "negative regulation of lens epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042343", "l": "indole glucosinolate metabolic process", "d": ["The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021617", "l": "glossopharyngeal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072696", "l": "positive regulation of DNA recombination at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.096636849693901", "identifiers": [{"i": "GO:0010243", "l": "response to organonitrogen compound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905937", "l": "negative regulation of germ cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070373", "l": "negative regulation of ERK1 and ERK2 cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000403", "l": "positive regulation of lymphocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009833", "l": "plant-type primary cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905120", "l": "cellular response to haloperidol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000911", "l": "cytokinesis by cell plate formation", "d": ["The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098908", "l": "regulation of neuronal action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048073", "l": "regulation of eye pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039668", "l": "viral entry into host cell via pilus basal pore", "d": ["The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900730", "l": "negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002258", "l": "positive regulation of kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035129", "l": "post-embryonic hindlimb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039723", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity", "d": ["Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035844", "l": "cloaca development", "d": ["The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903576", "l": "response to L-arginine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903922", "l": "negative regulation of protein processing in phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904522", "l": "positive regulation of myofibroblast cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052158", "l": "modulation by symbiont of host resistance gene-dependent defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060741", "l": "prostate gland stromal morphogenesis", "d": ["The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.533887529881525", "identifiers": [{"i": "GO:0032386", "l": "regulation of intracellular transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034382", "l": "chylomicron remnant clearance", "d": ["The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030536", "l": "larval feeding behavior", "d": ["Feeding behavior in a larval (immature) organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015765", "l": "methylgalactoside transport", "d": ["The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044032", "l": "modulation by symbiont of indole acetic acid levels in host", "d": ["The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002333", "l": "transitional one stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140916", "l": "zinc ion import into lysosome", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048743", "l": "positive regulation of skeletal muscle fiber development", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901425", "l": "response to formic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039522", "l": "suppression by virus of host mRNA export from nucleus", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002201", "l": "somatic diversification of DSCAM-based immune receptors", "d": ["The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021768", "l": "nucleus accumbens development", "d": ["The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032015", "l": "regulation of Ran protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ran protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070317", "l": "negative regulation of G0 to G1 transition", "d": ["A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0051452", "l": "intracellular pH reduction", "d": ["Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0050941", "l": "negative regulation of pigment cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007280", "l": "pole cell migration", "d": ["The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900052", "l": "regulation of retinoic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0010977", "l": "negative regulation of neuron projection development", "d": ["Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:2000846", "l": "regulation of corticosteroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048938", "l": "lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140898", "l": "CENP-A eviction from euchromatin", "d": ["A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.816481813363261", "identifiers": [{"i": "GO:0000280", "l": "nuclear division", "d": ["The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048891", "l": "lateral line ganglion neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003027", "l": "regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061436", "l": "establishment of skin barrier", "d": ["Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035177", "l": "larval foraging behavior", "d": ["The movement of a larva through a feeding substrate whilst feeding on food."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903976", "l": "negative regulation of glial cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086053", "l": "AV node cell to bundle of His cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.800603314158678", "identifiers": [{"i": "GO:0072521", "l": "purine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061418", "l": "regulation of transcription from RNA polymerase II promoter in response to hypoxia", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048140", "l": "male germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009395", "l": "phospholipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048795", "l": "swim bladder morphogenesis", "d": ["The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "34.017859912137759", "identifiers": [{"i": "GO:0050877", "l": "nervous system process", "d": ["A organ system process carried out by any of the organs or tissues of neurological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0090130", "l": "tissue migration", "d": ["The process in which the population of cells that make up a tissue undergo directed movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000264", "l": "negative regulation of blood coagulation, extrinsic pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090454", "l": "glutamate transmembrane import into vacuole", "d": ["The directed movement of glutamate into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043163", "l": "cell envelope organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0008584", "l": "male gonad development", "d": ["The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007053", "l": "spindle assembly involved in male meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042269", "l": "regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021971", "l": "corticospinal neuron axon guidance through the medullary pyramid", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048808", "l": "male genitalia morphogenesis", "d": ["The process in which the anatomical structures of male genitalia are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031335", "l": "regulation of sulfur amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033497", "l": "sinapate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097532", "l": "stress response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904642", "l": "cellular response to dinitrophenol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034140", "l": "negative regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903978", "l": "regulation of microglial cell activation", "d": ["Any process that modulates the frequency, rate or extent of microglial cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0009310", "l": "amine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045686", "l": "negative regulation of glial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032247", "l": "negative regulation of purine nucleoside transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0015837", "l": "amine transport", "d": ["The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0070591", "l": "ascospore wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900735", "l": "positive regulation of flocculation", "d": ["Any process that activates or increases the frequency, rate or extent of flocculation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990591", "l": "asparagine transmembrane import into vacuole", "d": ["The directed movement of asparagine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036297", "l": "interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006844", "l": "acyl carnitine transport", "d": ["The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010104", "l": "regulation of ethylene-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0120078", "l": "cell adhesion involved in sprouting angiogenesis", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090086", "l": "negative regulation of protein deubiquitination", "d": ["Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099018", "l": "evasion by virus of host restriction-modification system", "d": ["Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900148", "l": "negative regulation of Schwann cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043132", "l": "NAD transport", "d": ["The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001095", "l": "mannotriose transport", "d": ["The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060793", "l": "sweat gland placode formation", "d": ["The developmental process in which the sweat gland placode forms. 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Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140256", "l": "negative regulation of cellular response to phosphate starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031638", "l": "zymogen activation", "d": ["The proteolytic processing of an inactive enzyme to an active form."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.528458322397171", "identifiers": [{"i": "GO:0060341", "l": "regulation of cellular localization", "d": ["Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097298", "l": "regulation of nucleus size", "d": ["Any process that modulates the size of the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034391", "l": "regulation of smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.408607444211199", "identifiers": [{"i": "GO:0060627", "l": "regulation of vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.316032931461514", "identifiers": [{"i": "GO:0010605", "l": "negative regulation of macromolecule metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010659", "l": "cardiac muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071811", "l": "positive regulation of fever generation by positive regulation of prostaglandin biosynthesis", "d": ["Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902843", "l": "positive regulation of netrin-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002247", "l": "clearance of damaged tissue involved in inflammatory response wound healing", "d": ["The series of events leading to removal of necrotic debris that contribute to an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075189", "l": "positive regulation of hyphopodium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015823", "l": "phenylalanine transport", "d": ["The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002760", "l": "positive regulation of antimicrobial humoral response", "d": ["Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0070507", "l": "regulation of microtubule cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007096", "l": "regulation of exit from mitosis", "d": ["Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900720", "l": "negative regulation of uterine smooth muscle relaxation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006392", "l": "transcription elongation by mitochondrial RNA polymerase", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033103", "l": "protein secretion by the type VI secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0050804", "l": "modulation of chemical synaptic transmission", "d": ["Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039645", "l": "perturbation by virus of host G1/S transition checkpoint", "d": ["A process in which a virus interferes with the normal execution of the host cell G1/S transition checkpoint. 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This takes place during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019307", "l": "mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090318", "l": "regulation of chylomicron remodeling", "d": ["Any process that modulates the rate, frequency, or extent of chylomicron remodeling. 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This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902997", "l": "negative regulation of neurofibrillary tangle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090141", "l": "positive regulation of mitochondrial fission", "d": ["Any process that increases the rate, frequency or extent of mitochondrial fission. 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Under certain conditions, these structures can revert back to the features of their ancestors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010667", "l": "negative regulation of cardiac muscle cell apoptotic process", "d": ["Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009933", "l": "meristem structural organization", "d": ["Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018267", "l": "GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060673", "l": "cell-cell signaling involved in placenta development", "d": ["Any process that mediates the transfer of information from one cell to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0044347", "l": "cell wall polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904637", "l": "cellular response to ionomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061204", "l": "paramyosin filament assembly or disassembly", "d": ["The formation or disassembly of a filament composed of paramyosin molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048633", "l": "positive regulation of skeletal muscle tissue growth", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900557", "l": "emericellamide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901996", "l": "regulation of indoleacetic acid biosynthetic process via tryptophan", "d": ["Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060174", "l": "limb bud formation", "d": ["The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0043474", "l": "pigment metabolic process involved in pigmentation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0051646", "l": "mitochondrion localization", "d": ["Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.246643653717491", "identifiers": [{"i": "GO:0140013", "l": "meiotic nuclear division", "d": ["One of the two nuclear divisions that occur as part of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061244", "l": "mesonephric S-shaped body morphogenesis", "d": ["The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904583", "l": "response to polyamine macromolecule", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097202", "l": "activation of cysteine-type endopeptidase activity", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030042", "l": "actin filament depolymerization", "d": ["Disassembly of actin filaments by the removal of actin monomers from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120266", "l": "positive regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000408", "l": "negative regulation of T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.959548363731535", "identifiers": [{"i": "GO:0061526", "l": "acetylcholine secretion", "d": ["The regulated release of acetylcholine by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062055", "l": "photosynthetic state transition", "d": ["A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000297", "l": "negative regulation of synapse maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002231", "l": "detection of oomycetes", "d": ["The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071717", "l": "thromboxane transport", "d": ["The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000002", "l": "negative regulation of DNA damage checkpoint", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032817", "l": "regulation of natural killer cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019592", "l": "mannitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0070254", "l": "mucus secretion", "d": ["The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905584", "l": "outer hair cell apoptotic process", "d": ["Any apoptotic process in an outer hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051443", "l": "positive regulation of ubiquitin-protein transferase activity", "d": ["Any process that activates, maintains or increases the rate of ubiquitin transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010002", "l": "cardioblast differentiation", "d": ["The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000270", "l": "peptidoglycan metabolic process", "d": ["The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030152", "l": "bacteriocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019057", "l": "modulation by virus of host translation", "d": ["Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905944", "l": "positive regulation of formation of growth cone in injured axon", "d": ["Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035810", "l": "positive regulation of urine volume", "d": ["Any process that increases the amount of urine excreted from the body over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072306", "l": "positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071611", "l": "granulocyte colony-stimulating factor production", "d": ["The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021901", "l": "early neuron fate commitment in forebrain", "d": ["The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015829", "l": "valine transport", "d": ["The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901465", "l": "positive regulation of tetrapyrrole biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904524", "l": "negative regulation of DNA amplification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034118", "l": "regulation of erythrocyte aggregation", "d": ["Any process that modulates the frequency, rate, or extent of erythrocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032888", "l": "regulation of mitotic spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903408", "l": "positive regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0034471", "l": "ncRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of a non-coding RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003186", "l": "tricuspid valve morphogenesis", "d": ["The process in which the structure of the tricuspid valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0045937", "l": "positive regulation of phosphate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003039", "l": "detection of reduced oxygen by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098937", "l": "anterograde dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0015736", "l": "hexuronate transmembrane transport", "d": ["The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070874", "l": "negative regulation of glycogen metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010986", "l": "positive regulation of lipoprotein particle clearance", "d": ["Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003297", "l": "heart wedging", "d": ["The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.088743121718693", "identifiers": [{"i": "GO:0046483", "l": "heterocycle metabolic process", "d": ["The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0072148", "l": "epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072194", "l": "kidney smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061439", "l": "kidney vasculature morphogenesis", "d": ["The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0001912", "l": "positive regulation of leukocyte mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045649", "l": "regulation of macrophage differentiation", "d": ["Any process that modulates the frequency, rate or extent of macrophage differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000567", "l": "regulation of memory T cell activation", "d": ["Any process that modulates the frequency, rate or extent of memory T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032892", "l": "positive regulation of organic acid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050774", "l": "negative regulation of dendrite morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048685", "l": "negative regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061309", "l": "cardiac neural crest cell development involved in outflow tract morphogenesis", "d": ["The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904285", "l": "regulation of protein-pyridoxal-5-phosphate linkage", "d": ["Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021943", "l": "formation of radial glial scaffolds", "d": ["The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060925", "l": "ventricular cardiac muscle cell fate commitment", "d": ["The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050872", "l": "white fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905581", "l": "positive regulation of low-density lipoprotein particle clearance", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006334", "l": "nucleosome assembly", "d": ["The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905085", "l": "regulation of bioluminescence", "d": ["Any process that modulates the frequency, rate or extent of bioluminescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097156", "l": "fasciculation of motor neuron axon", "d": ["The collection of motor neuron axons into a bundle of rods, known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0008203", "l": "cholesterol metabolic process", "d": ["The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032349", "l": "positive regulation of aldosterone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072673", "l": "lamellipodium morphogenesis", "d": ["A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902611", "l": "cellular response to N-phenylthiourea", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903928", "l": "cellular response to cyanide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061065", "l": "regulation of dauer larval development", "d": ["Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905771", "l": "negative regulation of mesodermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140736", "l": "positive regulation of lovastatin biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0050679", "l": "positive regulation of epithelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900548", "l": "heme B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.342154213198413", "identifiers": [{"i": "GO:0051129", "l": "negative regulation of cellular component organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003089", "l": "positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035670", "l": "plant-type ovary development", "d": ["The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902203", "l": "negative regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0070920", "l": "regulation of regulatory ncRNA processing", "d": ["Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900117", "l": "regulation of execution phase of apoptosis", "d": ["Any process that modulates the frequency, rate or extent of execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016264", "l": "gap junction assembly", "d": ["Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150127", "l": "regulation of interleukin-33 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-33 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007008", "l": "outer mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001844", "l": "protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045594", "l": "positive regulation of cumulus cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003042", "l": "vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097477", "l": "lateral motor column neuron migration", "d": ["The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120028", "l": "negative regulation of osmosensory signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002156", "l": "negative regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051127", "l": "positive regulation of actin nucleation", "d": ["Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072664", "l": "maintenance of protein location in peroxisome", "d": ["Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045827", "l": "negative regulation of isoprenoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019121", "l": "peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine", "d": ["The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0010761", "l": "fibroblast migration", "d": ["Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035685", "l": "helper T cell diapedesis", "d": ["The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009687", "l": "abscisic acid metabolic process", "d": ["The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900186", "l": "negative regulation of clathrin-dependent endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060921", "l": "sinoatrial node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021947", "l": "outward migration of deep nuclear neurons", "d": ["The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045647", "l": "negative regulation of erythrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050826", "l": "response to freezing", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010597", "l": "green leaf volatile biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002241", "l": "response to parasitic plant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042404", "l": "thyroid hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904155", "l": "DN2 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031271", "l": "lateral pseudopodium assembly", "d": ["The extension of a pseudopodium from the lateral area of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048905", "l": "anterior lateral line neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000193", "l": "positive regulation of fatty acid transport", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060385", "l": "axonogenesis involved in innervation", "d": ["The neurite development process that generates a long process of a neuron, as it invades a target tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001985", "l": "negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048781", "l": "regulation of cyanophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of cyanophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036047", "l": "peptidyl-lysine demalonylation", "d": ["The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050846", "l": "teichuronic acid metabolic process", "d": ["The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0043558", "l": "regulation of translational initiation in response to stress", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902446", "l": "regulation of shade avoidance", "d": ["Any process that modulates the frequency, rate or extent of shade avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901646", "l": "negative regulation of synoviocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035316", "l": "non-sensory hair organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019655", "l": "glycolytic fermentation to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001768", "l": "establishment of T cell polarity", "d": ["The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045341", "l": "MHC class I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071996", "l": "glutathione transmembrane import into vacuole", "d": ["The directed movement of glutathione into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060784", "l": "regulation of cell proliferation involved in tissue homeostasis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090241", "l": "negative regulation of histone H4 acetylation", "d": ["Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000425", "l": "pexophagy", "d": ["The selective autophagy process in which a peroxisome is degraded by macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905674", "l": "regulation of adaptive immune memory response", "d": ["Any process that modulates the frequency, rate or extent of adaptive immune memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003363", "l": "lamellipodium assembly involved in ameboidal cell migration", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.030965049734235", "identifiers": [{"i": "GO:0016032", "l": "viral process", "d": ["A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071494", "l": "cellular response to UV-C", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036256", "l": "cellular response to methylamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0002064", "l": "epithelial cell development", "d": ["The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905126", "l": "regulation of axo-dendritic protein transport", "d": ["Any process that modulates the frequency, rate or extent of axo-dendritic protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000486", "l": "cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072214", "l": "metanephric cortex development", "d": ["The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.514856771201437", "identifiers": [{"i": "GO:0019725", "l": "cellular homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070347", "l": "regulation of brown fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of brown fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015708", "l": "silicic acid import across plasma membrane", "d": ["The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903472", "l": "negative regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018015", "l": "N-terminal peptidyl-phenylalanine methylation", "d": ["The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.58597274768276", "identifiers": [{"i": "GO:0006767", "l": "water-soluble vitamin metabolic process", "d": ["The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042560", "l": "pteridine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046275", "l": "flavonoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032624", "l": "interleukin-20 production", "d": ["The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070654", "l": "sensory epithelium 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(guanine-N7)-methylation", "d": ["The process whereby a guanine in a tRNA is methylated at the N7 position of guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046895", "l": "N-terminal peptidyl-isoleucine methylation", "d": ["The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015010", "l": "tetrahydrocorphin metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904646", "l": "cellular response to amyloid-beta", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0008345", "l": "larval locomotory behavior", "d": ["Locomotory behavior in a larval (immature) organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0055059", "l": "asymmetric neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0031338", "l": "regulation of vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902326", "l": "positive regulation of chlorophyll biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003335", "l": "corneocyte development", "d": ["The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905554", "l": "negative regulation of vessel branching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002213", "l": "defense response to insect", "d": ["A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052542", "l": "defense response by callose deposition", "d": ["Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015861", "l": "cytidine transport", "d": ["The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001111", "l": "positive regulation of lens epithelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044078", "l": "positive regulation by symbiont of host receptor-mediated endocytosis", "d": ["Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003180", "l": "aortic valve morphogenesis", "d": ["The process in which the structure of the aortic valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905081", "l": "positive regulation of cerebellar neuron development", "d": ["Any process that activates or increases the frequency, rate or extent of cerebellar neuron development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021791", "l": "chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0006457", "l": "protein folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902999", "l": "negative regulation of phospholipid efflux", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044562", "l": "envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050427", "l": "3'-phosphoadenosine 5'-phosphosulfate metabolic process", "d": ["The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001171", "l": "positive regulation of ATP biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006415", "l": "translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060956", "l": "endocardial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019564", "l": "aerobic glycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0070232", "l": "regulation of T cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of T cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010933", "l": "positive regulation of macrophage tolerance induction", "d": ["Any process that increases the frequency, rate, or extent of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1901861", "l": "regulation of muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904542", "l": "regulation of free ubiquitin chain polymerization", "d": ["Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904502", "l": "regulation of lipophagy", "d": ["Any process that modulates the frequency, rate or extent of lipophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050939", "l": "regulation of early stripe melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904638", "l": "response to resveratrol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.949314868637913", "identifiers": [{"i": "GO:0000910", "l": "cytokinesis", "d": ["The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0001700", "l": "embryonic development via the syncytial blastoderm", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072015", "l": "podocyte development", "d": ["The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075223", "l": "regulation of sporangium germination", "d": ["Any process that modulates the frequency, rate or extent of sporangium germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071051", "l": "polyadenylation-dependent snoRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140739", "l": "NLRP6 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009829", "l": "cell wall modification involved in fruit ripening", "d": ["The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060156", "l": "milk ejection reflex", "d": ["A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0002292", "l": "T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0098719", "l": "sodium ion import across plasma membrane", "d": ["The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905416", "l": "regulation of amoeboid sperm motility", "d": ["Any process that modulates the frequency, rate or extent of amoeboid sperm motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000011", "l": "vacuole inheritance", "d": ["The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902243", "l": "copal-8-ol diphosphate(3-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061533", "l": "norepinephrine secretion, neurotransmission", "d": ["The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900297", "l": "regulation of hexasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of hexasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036178", "l": "filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0110110", "l": "positive regulation of animal organ morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090625", "l": "siRNA-mediated gene silencing by mRNA destabilization", "d": ["An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. 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A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032480", "l": "negative regulation of type I interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035701", "l": "hematopoietic stem cell migration", "d": ["The orderly movement of a hematopoietic stem cell from one site to another. 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A metanephric tubule is an epithelial tube that is part of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046367", "l": "allose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032738", "l": "positive regulation of interleukin-15 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-15 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903954", "l": "positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901055", "l": "trimethylenediamine metabolic process", "d": ["The chemical reactions and pathways involving trimethylenediamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901494", "l": "regulation of cysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0001960", "l": "negative regulation of cytokine-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903372", "l": "negative regulation of endoplasmic reticulum tubular network organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060583", "l": "regulation of actin cortical patch localization", "d": ["Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015828", "l": "tyrosine transport", "d": ["The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009856", "l": "pollination", "d": ["The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140057", "l": "vacuole-mitochondria membrane tethering", "d": ["The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905826", "l": "negative regulation of selenocysteine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901345", "l": "response to L-thialysine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903357", "l": "regulation of transcription initiation by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048582", "l": "positive regulation of post-embryonic development", "d": ["Any process that activates or increases the frequency, rate or extent of post-embryonic development. 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These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0090558", "l": "plant epidermis development", "d": ["The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010634", "l": "positive regulation of epithelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072272", "l": "proximal/distal pattern formation involved in metanephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060876", "l": "semicircular canal formation", "d": ["The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:0019218", "l": "regulation of steroid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010578", "l": "regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140881", "l": "positive regulation terrein biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of the fungal metabolite terrein."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0042713", "l": "sperm ejaculation", "d": ["The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0019827", "l": "stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042256", "l": "cytosolic ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006547", "l": "histidine metabolic process", "d": ["The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002132", "l": "wobble position uridine ribose methylation", "d": ["The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032071", "l": "regulation of endodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036210", "l": "protein modification process in another organism", "d": ["The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901490", "l": "regulation of lymphangiogenesis", "d": ["Any process that modulates the frequency, rate or extent of lymphangiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045459", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide", "d": ["The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016260", "l": "selenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007415", "l": "defasciculation of motor neuron axon", "d": ["Separation of a motor axon away from a bundle of axons known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000919", "l": "negative regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0045191", "l": "regulation of isotype switching", "d": ["Any process that modulates the frequency, rate or extent of isotype switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.326385679795735", "identifiers": [{"i": "GO:0045580", "l": "regulation of T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051045", "l": "negative regulation of membrane protein ectodomain proteolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0061180", "l": "mammary gland epithelium development", "d": ["The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901036", "l": "positive regulation of L-glutamine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0060837", "l": "blood vessel endothelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001155", "l": "negative regulation of glycolytic fermentation to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0000012", "l": "single strand break repair", "d": ["The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0055010", "l": "ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of cardiac ventricle muscle is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000482", "l": "maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019817", "l": "vesicle fusion with peroxisome", "d": ["The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900887", "l": "regulation of pentadecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018866", "l": "adamantanone metabolic process", "d": ["The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099002", "l": "viral genome ejection through host cell envelope, short tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042026", "l": "protein refolding", "d": ["The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070899", "l": "mitochondrial tRNA wobble uridine modification", "d": ["The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904182", "l": "regulation of pyruvate dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900613", "l": "F-9775B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F-9775B."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010909", "l": "positive regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071689", "l": "muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0044771", "l": "meiotic cell cycle phase transition", "d": ["The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032475", "l": "otolith formation", "d": ["The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034199", "l": "activation of protein kinase A activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0100009", "l": "regulation of fever generation by prostaglandin secretion", "d": ["Any prostaglandin secretion process that regulates fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003360", "l": "brainstem development", "d": ["The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0005977", "l": "glycogen metabolic process", "d": ["The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001562", "l": "response to protozoan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0007499", "l": "ectoderm and mesoderm interaction", "d": ["A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.533887529881525", "identifiers": [{"i": "GO:0051254", "l": "positive regulation of RNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905666", "l": "regulation of protein localization to endosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046676", "l": "negative regulation of insulin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0048806", "l": "genitalia development", "d": ["The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048150", "l": "behavioral response to ether", "d": ["Any process that results in a change in the behavior of an organism as a result of an ether stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110033", "l": "regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140649", "l": "cell-to-cell migration by invasive hypha", "d": ["The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904717", "l": "regulation of AMPA glutamate receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001192", "l": "maintenance of transcriptional fidelity during transcription elongation", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009138", "l": "pyrimidine nucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900023", "l": "positive regulation of D-erythro-sphingosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140251", "l": "regulation protein catabolic process at presynapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0051784", "l": "negative regulation of nuclear division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901382", "l": "regulation of chorionic trophoblast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033055", "l": "D-arginine metabolic process", "d": ["The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0045727", "l": "positive regulation of translation", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072393", "l": "microtubule anchoring at microtubule organizing center", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905512", "l": "regulation of short-term synaptic potentiation", "d": ["Any process that modulates the frequency, rate or extent of short-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022017", "l": "neuroblast division in pallium", "d": ["The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010306", "l": "rhamnogalacturonan II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090593", "l": "peptidyl-histidine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900444", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045036", "l": "protein targeting to chloroplast", "d": ["The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014073", "l": "response to tropane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090303", "l": "positive regulation of wound healing", "d": ["Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003101", "l": "regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine", "d": ["The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902341", "l": "xylitol transmembrane transport", "d": ["The directed movement of a xylitol across a membrane. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050747", "l": "positive regulation of lipoprotein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000960", "l": "regulation of mitochondrial RNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070318", "l": "positive regulation of G0 to G1 transition", "d": ["A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048688", "l": "negative regulation of sprouting of injured axon", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020013", "l": "modulation by symbiont of host erythrocyte aggregation", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0043582", "l": "sporangium development", "d": ["The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000192", "l": "negative regulation of fatty acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.481265292451688", "identifiers": [{"i": "GO:0071626", "l": "mastication", "d": ["The process of biting and mashing food with the teeth prior to swallowing."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.645268558415069", "identifiers": [{"i": "GO:0051604", "l": "protein maturation", "d": ["Any process leading to the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021942", "l": "radial glia guided migration of Purkinje cell", "d": ["The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904442", "l": "negative regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902196", "l": "isovaleryl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0000082", "l": "G1/S transition of mitotic cell cycle", "d": ["The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.297762971210318", "identifiers": [{"i": "GO:0061025", "l": "membrane fusion", "d": ["The membrane organization process that joins two lipid bilayers to form a single membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000502", "l": "negative regulation of natural killer cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001781", "l": "neutrophil apoptotic process", "d": ["Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072045", "l": "convergent extension involved in nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900956", "l": "regulation of 17-methylnonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000358", "l": "positive regulation of kidney smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036086", "l": "positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048099", "l": "anterior/posterior lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042039", "l": "vanadium incorporation into metallo-sulfur cluster", "d": ["The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071599", "l": "otic vesicle development", "d": ["The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001548", "l": "follicular fluid formation in ovarian follicle antrum", "d": ["The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035440", "l": "tuberculosinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990787", "l": "negative regulation of hh target transcription factor activity", "d": ["Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001715", "l": "ectodermal cell fate specification", "d": ["The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902522", "l": "response to 4'-epidoxorubicin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032604", "l": "granulocyte macrophage colony-stimulating factor production", "d": ["The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.989777303936307", "identifiers": [{"i": "GO:0042254", "l": "ribosome biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002806", "l": "negative regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0032252", "l": "secretory granule localization", "d": ["Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071318", "l": "cellular response to ATP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903563", "l": "microtubule bundle formation involved in horsetail-astral microtubule organization", "d": ["Any microtubule bundle formation that is involved in horsetail-astral microtubule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001025", "l": "positive regulation of response to drug", "d": ["Any process that activates or increases the frequency, rate or extent of response to drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0042325", "l": "regulation of phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1901073", "l": "glucosamine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018301", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon", "d": ["The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033357", "l": "L-arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.896021600509201", "identifiers": [{"i": "GO:0060322", "l": "head development", "d": ["The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903459", "l": "mitotic DNA replication lagging strand elongation", "d": ["Any lagging strand elongation that is involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900229", "l": "negative regulation of single-species biofilm formation in or on host organism", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010729", "l": "positive regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902013", "l": "poly(glycerol phosphate) teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905800", "l": "negative regulation of intraciliary retrograde transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0098513", "l": "detection of humidity", "d": ["The series of events in which a humidity stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019466", "l": "ornithine catabolic process via proline", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075251", "l": "uredospore formation", "d": ["The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045328", "l": "cytochrome P450 4A1-heme linkage", "d": ["The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0008210", "l": "estrogen metabolic process", "d": ["The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010561", "l": "negative regulation of glycoprotein biosynthetic process", "d": ["Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900299", "l": "positive regulation of hexasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of hexasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072386", "l": "plus-end-directed organelle transport along microtubule", "d": ["The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902060", "l": "positive regulation of sporocarp development involved in sexual reproduction", "d": ["Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032790", "l": "ribosome disassembly", "d": ["The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0099518", "l": "vesicle cytoskeletal trafficking", "d": ["The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051492", "l": "regulation of stress fiber assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030214", "l": "hyaluronan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071336", "l": "regulation of hair follicle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904538", "l": "regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006855", "l": "xenobiotic transmembrane transport", "d": ["The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035028", "l": "leading edge cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055046", "l": "microgametogenesis", "d": ["The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904799", "l": "regulation of neuron remodeling", "d": ["Any process that modulates the frequency, rate or extent of neuron remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060307", "l": "regulation of ventricular cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0015854", "l": "guanine transport", "d": ["The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046228", "l": "2,4,5-trichlorophenoxyacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070200", "l": "establishment of protein localization to telomere", "d": ["The directed movement of a protein to a specific location in the telomeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048724", "l": "epistomal sclerite development", "d": ["The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090441", "l": "trehalose biosynthesis in response to heat stress", "d": ["The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032417", "l": "positive regulation of sodium:proton antiporter activity", "d": ["Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006361", "l": "transcription initiation at RNA polymerase I promoter", "d": ["A transcription initiation process that takes place at a RNA polymerase I gene promoter. 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An example of this process is found in the Gnathostomata."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0046545", "l": "development of primary female sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903849", "l": "positive regulation of aorta morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of aorta morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043580", "l": "periplasmic space organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032655", "l": "regulation of interleukin-12 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-12 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905109", "l": "regulation of pulmonary blood vessel remodeling", "d": ["Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002502", "l": "peptide antigen assembly with MHC class I protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032664", "l": "regulation of interleukin-20 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097324", "l": "melanocyte migration", "d": ["The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033087", "l": "negative regulation of immature T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010136", "l": "ureide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905536", "l": "negative regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019449", "l": "L-cysteine catabolic process to hypotaurine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.20011737869816", "identifiers": [{"i": "GO:0050790", "l": "regulation of catalytic activity", "d": ["Any process that modulates the activity of an enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120139", "l": "positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0042133", "l": "neurotransmitter metabolic process", "d": ["The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098961", "l": "dendritic transport of ribonucleoprotein complex", "d": ["The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021842", "l": "chemorepulsion involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051352", "l": "negative regulation of ligase activity", "d": ["Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019676", "l": "ammonia assimilation cycle", "d": ["The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048703", "l": "embryonic viscerocranium morphogenesis", "d": ["The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045640", "l": "regulation of basophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of basophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033526", "l": "tetrapyrrole biosynthetic process from glutamate", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036279", "l": "positive regulation of protein export from nucleus in response to glucose starvation", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075277", "l": "positive regulation of telium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097316", "l": "cellular response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003067", "l": "circadian regulation of systemic arterial blood pressure by hormone", "d": ["The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900022", "l": "regulation of D-erythro-sphingosine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0016358", "l": "dendrite development", "d": ["The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006776", "l": "vitamin A metabolic process", "d": ["The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019373", "l": "epoxygenase P450 pathway", "d": ["The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061103", "l": "carotid body glomus cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0002823", "l": "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903382", "l": "negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044417", "l": "translocation of molecules into host", "d": ["The directed movement of a molecule(s) produced by an organism to a location inside its host organism. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070072", "l": "vacuolar proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000489", "l": "regulation of hepatic stellate cell activation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0046189", "l": "phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901711", "l": "negative regulation of homoserine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009733", "l": "response to auxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044793", "l": "negative regulation by host of viral process", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900742", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010351", "l": "lithium ion transport", "d": ["The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018395", "l": "peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016082", "l": "synaptic vesicle priming", "d": ["A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019550", "l": "glutamate catabolic process to aspartate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001195", "l": "negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075112", "l": "perturbation of host transmembrane receptor-mediated signal transduction", "d": ["Any process in which the symbiont alters a transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098778", "l": "curli subunit secretion coupled to curli assembly", "d": ["The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019477", "l": "L-lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110054", "l": "regulation of actin filament annealing", "d": ["Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098971", "l": "anterograde dendritic transport of neurotransmitter receptor complex", "d": ["The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035043", "l": "male pronuclear envelope synthesis", "d": ["Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030398", "l": "peroxisomal membrane disassembly", "d": ["The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003033", "l": "detection of hypoxic conditions in blood by aortic body chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003178", "l": "coronary sinus valve development", "d": ["The progression of the valve of the coronary sinus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048456", "l": "stamen structural organization", "d": ["The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006405", "l": "RNA export from nucleus", "d": ["The directed movement of RNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045863", "l": "negative regulation of pteridine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060888", "l": "limb epidermis stratification", "d": ["The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0071459", "l": "protein localization to chromosome, centromeric region", "d": ["Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0000912", "l": "assembly of actomyosin apparatus involved in cytokinesis", "d": ["The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030208", "l": "dermatan sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120040", "l": "regulation of macrophage proliferation", "d": ["Any process that modulates the frequency, rate or extent of macrophage proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0009994", "l": "oocyte differentiation", "d": ["The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.807532506208567", "identifiers": [{"i": "GO:0006811", "l": "monoatomic ion transport", "d": ["The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000182", "l": "regulation of progesterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of progesterone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042559", "l": "pteridine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0019058", "l": "viral life cycle", "d": ["A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900761", "l": "averantin metabolic process", "d": ["The chemical reactions and pathways involving averantin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902193", "l": "2-methylbut-2-enoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032824", "l": "negative regulation of natural killer cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904120", "l": "positive regulation of otic vesicle morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033470", "l": "gibberellin 12 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0099519", "l": "dense core granule cytoskeletal transport", "d": ["The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090685", "l": "RNA localization to nucleus", "d": ["A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902662", "l": "regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048394", "l": "intermediate mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035345", "l": "regulation of hypoxanthine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904273", "l": "L-alanine import across plasma membrane", "d": ["The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016045", "l": "detection of bacterium", "d": ["The series of events in which a stimulus from a bacterium is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0040037", "l": "negative regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0050779", "l": "RNA destabilization", "d": ["Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.681872163386743", "identifiers": [{"i": "GO:0072080", "l": "nephron tubule development", "d": ["The progression of a nephron tubule over time, from its initial formation to the mature structure. 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The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900484", "l": "negative regulation of protein targeting to vacuolar membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000409", "l": "regulation of transcription by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent or transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035044", "l": "sperm aster formation", "d": ["Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018975", "l": "anaerobic 2,4,6-trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900816", "l": "ochratoxin A metabolic process", "d": ["The chemical reactions and pathways involving ochratoxin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071788", "l": "endoplasmic reticulum tubular network maintenance", "d": ["The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903944", "l": "negative regulation of hepatocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0070665", "l": "positive regulation of leukocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0070590", "l": "spore wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001051", "l": "positive regulation of tendon cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tendon cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071792", "l": "bacillithiol metabolic process", "d": ["The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0021575", "l": "hindbrain morphogenesis", "d": ["The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0016999", "l": "antibiotic metabolic process", "d": ["The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000467", "l": "positive regulation of glycogen (starch) synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140925", "l": "L-phenylalanine import across plasma membrane", "d": ["The directed movement of L-phenylalanine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0015865", "l": "purine nucleotide transport", "d": ["The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060747", "l": "oral incubation", "d": ["A parental behavior in which fertilized eggs are taken into the mouth and held until hatching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090281", "l": "negative regulation of calcium ion import", "d": ["Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051388", "l": "positive regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035789", "l": "metanephric mesenchymal cell migration", "d": ["The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002077", "l": "acrosome matrix dispersal", "d": ["The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.361282203588587", "identifiers": [{"i": "GO:0002366", "l": "leukocyte activation involved in immune response", "d": ["A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0009142", "l": "nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042023", "l": "DNA endoreduplication", "d": ["Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902745", "l": "positive regulation of lamellipodium organization", "d": ["Any process that activates or increases the frequency, rate or extent of lamellipodium organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072340", "l": "lactam catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.616234936174635", "identifiers": [{"i": "GO:0002449", "l": "lymphocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a lymphocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010938", "l": "cytoplasmic microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021561", "l": "facial nerve development", "d": ["The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000949", "l": "aromatic amino acid family catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010263", "l": "tricyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010603", "l": "regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042000", "l": "translocation of peptides or proteins into host", "d": ["The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018925", "l": "m-cresol metabolic process", "d": ["The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021693", "l": "cerebellar Purkinje cell layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018890", "l": "cyanamide metabolic process", "d": ["The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036171", "l": "filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.7749374156081", "identifiers": [{"i": "GO:0010876", "l": "lipid localization", "d": ["Any process in which a lipid is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031641", "l": "regulation of myelination", "d": ["Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070349", "l": "positive regulation of brown fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of brown fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036509", "l": "trimming of terminal mannose on B branch", "d": ["The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140495", "l": "migracytosis", "d": ["A cell migration-dependent mechanism for releasing cellular contents."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902349", "l": "response to chloroquine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048194", "l": "Golgi vesicle budding", "d": ["The evagination of the Golgi membrane, resulting in formation of a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051122", "l": "hepoxilin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001702", "l": "gastrulation with mouth forming second", "d": ["A gastrulation process in which the initial invagination becomes the anus and the mouth forms second."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009793", "l": "embryo development ending in seed dormancy", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903952", "l": "regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905118", "l": "positive regulation of ribonucleoside-diphosphate reductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001949", "l": "sebaceous gland cell differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903902", "l": "positive regulation of viral life cycle", "d": ["Any process that activates or increases the frequency, rate or extent of viral life cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008618", "l": "7-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046274", "l": "lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0003229", "l": "ventricular cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030237", "l": "female sex determination", "d": ["The specification of female sex of an individual organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000477", "l": "generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072249", "l": "metanephric podocyte development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009113", "l": "purine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009803", "l": "cinnamic acid metabolic process", "d": ["The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0007097", "l": "nuclear migration", "d": ["The directed movement of the nucleus to a specific location within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071490", "l": "cellular response to far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075278", "l": "negative regulation of telium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045494", "l": "photoreceptor cell maintenance", "d": ["Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140455", "l": "cytoplasm protein quality control", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001277", "l": "negative regulation of leucine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904843", "l": "cellular response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018875", "l": "anaerobic benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905559", "l": "positive regulation of mitotic nuclear envelope disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060296", "l": "regulation of cilium beat frequency involved in ciliary motility", "d": ["Any process that modulates the frequency of cilium beating involved in ciliary motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044001", "l": "migration in host", "d": ["The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905401", "l": "positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000048", "l": "negative regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903221", "l": "regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that modulates the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905308", "l": "cellular response to miconazole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0048443", "l": "stamen development", "d": ["The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904331", "l": "regulation of error-prone translesion synthesis", "d": ["Any process that modulates the frequency, rate or extent of error-prone translesion synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0036092", "l": "phosphatidylinositol-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003063", "l": "negative regulation of heart rate by acetylcholine", "d": ["The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900705", "l": "negative regulation of siderophore biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002370", "l": "natural killer cell cytokine production", "d": ["Any process that contributes to cytokine production by a natural killer cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904619", "l": "response to dimethyl sulfoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000225", "l": "negative regulation of testosterone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009205", "l": "purine ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120010", "l": "intermembrane phospholipid transfer", "d": ["The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902158", "l": "positive regulation of response to G2 DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901492", "l": "positive regulation of lymphangiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of lymphangiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000755", "l": "cytogamy", "d": ["During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044506", "l": "modulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006124", "l": "ferredoxin metabolic process", "d": ["The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0046633", "l": "alpha-beta T cell proliferation", "d": ["The expansion of an alpha-beta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052574", "l": "UDP-galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099044", "l": "vesicle tethering to endoplasmic reticulum", "d": ["The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042778", "l": "tRNA end turnover", "d": ["The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072537", "l": "fibroblast activation", "d": ["A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0090277", "l": "positive regulation of peptide hormone secretion", "d": ["Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046656", "l": "folic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046359", "l": "butyrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009645", "l": "response to low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904937", "l": "sensory neuron migration", "d": ["The orderly movement of a sensory neuron from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000742", "l": "karyogamy involved in conjugation with cellular fusion", "d": ["During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901081", "l": "negative regulation of relaxation of smooth muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900503", "l": "regulation of cellulosome assembly", "d": ["Any process that modulates the frequency, rate or extent of cellulosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038004", "l": "epidermal growth factor receptor ligand maturation", "d": ["Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905180", "l": "positive regulation of cardiac muscle tissue regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009148", "l": "pyrimidine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099552", "l": "trans-synaptic signaling by lipid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061068", "l": "urethra development", "d": ["The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019367", "l": "fatty acid elongation, saturated fatty acid", "d": ["Elongation of a saturated fatty acid chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0035933", "l": "glucocorticoid secretion", "d": ["The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903807", "l": "L-threonine import across plasma membrane", "d": ["The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044821", "l": "meiotic telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0032069", "l": "regulation of nuclease activity", "d": ["Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060039", "l": "pericardium development", "d": ["The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016198", "l": "axon choice point recognition", "d": ["The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990236", "l": "proteasome core complex import into nucleus", "d": ["The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903454", "l": "regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000756", "l": "response to pheromone regulating conjugation with mutual genetic exchange", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0035265", "l": "organ growth", "d": ["The increase in size or mass of an organ. 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These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.240937671532407", "identifiers": [{"i": "GO:0050890", "l": "cognition", "d": ["The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021595", "l": "rhombomere structural organization", "d": ["The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900903", "l": "negative regulation of hexadecanal biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031412", "l": "gas vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019594", "l": "mannitol metabolic process", "d": ["The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061635", "l": "regulation of protein complex stability", "d": ["Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015753", "l": "D-xylose transmembrane transport", "d": ["The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000789", "l": "positive regulation of venous endothelial cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0046636", "l": "negative regulation of alpha-beta T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010076", "l": "maintenance of floral meristem identity", "d": ["The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000705", "l": "achiasmate meiosis I", "d": ["The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.330990311268877", "identifiers": [{"i": "GO:0010565", "l": "regulation of cellular ketone metabolic process", "d": ["Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072168", "l": "specification of anterior mesonephric tubule identity", "d": ["The process in which the tubules of the anterior mesonephros acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902018", "l": "negative regulation of cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051663", "l": "oocyte nucleus localization involved in oocyte dorsal/ventral axis specification", "d": ["The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034169", "l": "positive regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048894", "l": "efferent axon development in a lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0035898", "l": "parathyroid hormone secretion", "d": ["The regulated release of parathyroid hormone into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000392", "l": "regulation of lamellipodium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072005", "l": "maintenance of kidney identity", "d": ["The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0006690", "l": "icosanoid metabolic process", "d": ["The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035159", "l": "regulation of tube length, open tracheal system", "d": ["Ensuring that a tube in an open tracheal system is of the correct length."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006141", "l": "regulation of purine nucleobase metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006236", "l": "cytidine salvage", "d": ["Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0032446", "l": "protein modification by small protein conjugation", "d": ["A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042867", "l": "pyruvate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901395", "l": "regulation of transforming growth factor beta2 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080152", "l": "regulation of reductive pentose-phosphate cycle", "d": ["Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0060491", "l": "regulation of cell projection assembly", "d": ["Any process that modulates the rate, frequency, or extent of cell projection assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903945", "l": "positive regulation of hepatocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.152088137740293", "identifiers": [{"i": "GO:0098754", "l": "detoxification", "d": ["Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.799876679198697", "identifiers": [{"i": "GO:0048863", "l": "stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018288", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030194", "l": "positive regulation of blood coagulation", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0052315", "l": "phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019304", "l": "anaerobic rhamnose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097736", "l": "aerial mycelium formation", "d": ["The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905788", "l": "negative regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048798", "l": "swim bladder inflation", "d": ["The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051092", "l": "positive regulation of NF-kappaB transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001207", "l": "regulation of transcription elongation by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903413", "l": "cellular response to bile acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900128", "l": "regulation of G-protein activated inward rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905497", "l": "negative regulation of triplex DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035802", "l": "adrenal cortex formation", "d": ["The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901670", "l": "negative regulation of superoxide dismutase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900194", "l": "negative regulation of oocyte maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000759", "l": "regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061987", "l": "negative regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0099175", "l": "regulation of postsynapse organization", "d": ["Any process that modulates the physical form of a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905880", "l": "negative regulation of oogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0036342", "l": "post-anal tail morphogenesis", "d": ["The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036522", "l": "negative regulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901266", "l": "cephalosporin C metabolic process", "d": ["The chemical reactions and pathways involving cephalosporin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019616", "l": "catechol catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019919", "l": "peptidyl-arginine methylation, to asymmetrical-dimethyl arginine", "d": ["The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010046", "l": "response to mycotoxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902816", "l": "regulation of protein localization to microtubule", "d": ["Any process that modulates the frequency, rate or extent of protein localization to microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901421", "l": "positive regulation of response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of response to alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000879", "l": "negative regulation of dipeptide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090103", "l": "cochlea morphogenesis", "d": ["The process in which the cochlea is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044499", "l": "envenomation resulting in positive regulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034267", "l": "discadenine metabolic process", "d": ["The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060912", "l": "cardiac cell fate specification", "d": ["The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905495", "l": "positive regulation of G-quadruplex DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090532", "l": "L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061435", "l": "positive regulation of transcription from a mobile element promoter", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010814", "l": "substance P catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048544", "l": "recognition of pollen", "d": ["A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007436", "l": "larval salivary gland morphogenesis", "d": ["The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0071675", "l": "regulation of mononuclear cell migration", "d": ["Any process that modulates the rate, frequency or extent of mononuclear cell migration. 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These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070105", "l": "positive regulation of interleukin-6-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902928", "l": "inulin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021722", "l": "superior olivary nucleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052784", "l": "reuteran biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072043", "l": "regulation of pre-tubular aggregate formation by cell-cell signaling", "d": ["Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019609", "l": "3-hydroxyphenylacetate metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035714", "l": "cellular response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140627", "l": "ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0140694", "l": "non-membrane-bounded organelle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901231", "l": "positive regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007557", "l": "regulation of juvenile hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0030447", "l": "filamentous growth", "d": ["The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000458", "l": "regulation of astrocyte chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of astrocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0015810", "l": "aspartate transmembrane transport", "d": ["The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.681872163386743", "identifiers": [{"i": "GO:0006006", "l": "glucose metabolic process", "d": ["The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001720", "l": "conversion of lysyl-tRNA to pyrrolysyl-tRNA", "d": ["The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070236", "l": "negative regulation of activation-induced cell death of T cells", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070630", "l": "(1->4)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033574", "l": "response to testosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905413", "l": "regulation of dense core granule exocytosis", "d": ["Any process that modulates the frequency, rate or extent of dense core granule exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900586", "l": "arugosin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arugosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903549", "l": "positive regulation of growth hormone activity", "d": ["Any process that activates or increases the frequency, rate or extent of growth hormone activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0001914", "l": "regulation of T cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033056", "l": "D-ornithine metabolic process", "d": ["The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045712", "l": "positive regulation of larval salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032978", "l": "protein insertion into membrane from inner side", "d": ["The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010112", "l": "regulation of systemic acquired resistance", "d": ["Any process that modulates the frequency, rate or extent of systemic acquired resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904757", "l": "positive regulation of gut granule assembly", "d": ["Any process that activates or increases the frequency, rate or extent of gut granule assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048897", "l": "myelination of lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of a lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060020", "l": "Bergmann glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061820", "l": "telomeric D-loop disassembly", "d": ["A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050971", "l": "detection of mechanical stimulus involved in magnetoreception", "d": ["The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046619", "l": "lens placode formation involved in camera-type eye formation", "d": ["Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052644", "l": "chlorophyllide a metabolic process", "d": ["The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070999", "l": "detection of mechanical stimulus involved in sensory perception of gravity", "d": ["The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0072007", "l": "mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900553", "l": "asperfuranone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asperfuranone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902756", "l": "sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048648", "l": "caste determination", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001246", "l": "negative regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0060841", "l": "venous blood vessel development", "d": ["The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072176", "l": "nephric duct development", "d": ["The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046225", "l": "bacteriocin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015795", "l": "sorbitol transmembrane transport", "d": ["The directed movement of sorbitol across a membrane. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045762", "l": "positive regulation of adenylate cyclase activity", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019061", "l": "uncoating of virus", "d": ["The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075219", "l": "modulation of zoospore encystment on host", "d": ["Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000586", "l": "regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900654", "l": "positive regulation of demethylkotanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036259", "l": "aerobic raffinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.725576423494985", "identifiers": [{"i": "GO:0051246", "l": "regulation of protein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071864", "l": "positive regulation of cell proliferation in bone marrow", "d": ["A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904154", "l": "positive regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033571", "l": "lactoferrin transport", "d": ["The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010589", "l": "leaf proximal/distal pattern formation", "d": ["The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061361", "l": "positive regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015985", "l": "energy coupled proton transport, down electrochemical gradient", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009810", "l": "stilbene metabolic process", "d": ["The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0072593", "l": "reactive oxygen species metabolic process", "d": ["The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035455", "l": "response to interferon-alpha", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0036065", "l": "fucosylation", "d": ["The covalent attachment of a fucosyl group to an acceptor molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904229", "l": "regulation of succinate dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071415", "l": "cellular response to purine-containing compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905217", "l": "response to astaxanthin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000692", "l": "negative regulation of seed maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031117", "l": "positive regulation of microtubule depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0009698", "l": "phenylpropanoid metabolic process", "d": ["The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003050", "l": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "d": ["The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032918", "l": "spermidine acetylation", "d": ["The modification of spermidine by addition of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901481", "l": "L-glutamate import involved in cellular response to nitrogen starvation", "d": ["Any L-glutamate import that is involved in cellular response to nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030264", "l": "nuclear fragmentation involved in apoptotic nuclear change", "d": ["The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0055075", "l": "potassium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902817", "l": "negative regulation of protein localization to microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032646", "l": "regulation of hepatocyte growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071981", "l": "exit from diapause", "d": ["The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002909", "l": "negative regulation of peripheral B cell deletion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051121", "l": "hepoxilin metabolic process", "d": ["The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060616", "l": "mammary gland cord formation", "d": ["The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0002718", "l": "regulation of cytokine production involved in immune response", "d": ["Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062102", "l": "female germline stem cell symmetric division", "d": ["Division of a female germline stem cell to produce two germline stem cells of the same type as the parent."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070782", "l": "phosphatidylserine exposure on apoptotic cell surface", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009156", "l": "ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019241", "l": "citrulline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090205", "l": "positive regulation of cholesterol metabolic process", "d": ["Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090373", "l": "negative regulation of glycerol transport", "d": ["Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060354", "l": "negative regulation of cell adhesion molecule production", "d": ["Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035774", "l": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006142", "l": "regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009145", "l": "purine nucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "33.343574071332561", "identifiers": [{"i": "GO:0007369", "l": "gastrulation", "d": ["A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097081", "l": "vascular associated smooth muscle cell fate commitment", "d": ["The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. 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Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0050748", "l": "negative regulation of lipoprotein metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019709", "l": "iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "d": ["The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990818", "l": "L-arginine transmembrane export from vacuole", "d": ["The directed movement of L-arginine out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905314", "l": "semi-lunar valve development", "d": ["The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010915", "l": "regulation of very-low-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. 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This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019513", "l": "lactose catabolic process, using glucoside 3-dehydrogenase", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042058", "l": "regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019102", "l": "male somatic sex determination", "d": ["The determination of sex and sexual phenotypes in a male organism's soma."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000413", "l": "regulation of fibronectin-dependent thymocyte migration", "d": ["Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902623", "l": "negative regulation of neutrophil migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045961", "l": "negative regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042437", "l": "indoleacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.657393168258849", "identifiers": [{"i": "GO:0045333", "l": "cellular respiration", "d": ["The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140966", "l": "piRNA-mediated heterochromatin formation", "d": ["The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering piRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0086010", "l": "membrane depolarization during action potential", "d": ["The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001011", "l": "positive regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071379", "l": "cellular response to prostaglandin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090514", "l": "L-tyrosine transmembrane import into vacuole", "d": ["The directed movement of L-tyrosine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060157", "l": "urinary bladder development", "d": ["The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0003207", "l": "cardiac chamber formation", "d": ["The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021690", "l": "cerebellar molecular layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046277", "l": "methylgallate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902458", "l": "positive regulation of stomatal opening", "d": ["Any process that activates or increases the frequency, rate or extent of stomatal opening."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060980", "l": "cell migration involved in coronary vasculogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071042", "l": "nuclear polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002738", "l": "positive regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019482", "l": "beta-alanine metabolic process", "d": ["The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905425", "l": "negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990074", "l": "polyuridylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003083", "l": "negative regulation of renal output by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061914", "l": "negative regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002575", "l": "basophil chemotaxis", "d": ["The movement of a basophil in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006541", "l": "glutamine metabolic process", "d": ["The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0072525", "l": "pyridine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061319", "l": "nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904658", "l": "positive regulation of sensory perception of sweet taste", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900941", "l": "regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021890", "l": "olfactory bulb interneuron fate commitment", "d": ["The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090549", "l": "response to carbon starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900276", "l": "regulation of proteinase activated receptor activity", "d": ["Any process that modulates the frequency, rate or extent of proteinase activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046038", "l": "GMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0086003", "l": "cardiac muscle cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900312", "l": "regulation of maltohexaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltohexaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1905038", "l": "regulation of membrane lipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of membrane lipid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901687", "l": "glutathione derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutathione derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:2000779", "l": "regulation of double-strand break repair", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010750", "l": "positive regulation of nitric oxide mediated signal transduction", "d": ["Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. 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The fungal-type cell wall contains beta-glucan and may contain chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032700", "l": "negative regulation of interleukin-17 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901521", "l": "aspyridone B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspyridone B."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903044", "l": "protein localization to membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0046496", "l": "nicotinamide nucleotide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0048512", "l": "circadian behavior", "d": ["The specific behavior of an organism that recurs with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042177", "l": "negative regulation of protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032515", "l": "negative regulation of phosphoprotein phosphatase activity", "d": ["Any process that stops or reduces the activity of a phosphoprotein phosphatase."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072221", "l": "metanephric distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043578", "l": "nuclear matrix organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902971", "l": "mitotic DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0030225", "l": "macrophage differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901765", "l": "phosphinothricin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphinothricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007402", "l": "ganglion mother cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120075", "l": "positive regulation of endocardial cushion cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015727", "l": "lactate transport", "d": ["The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900901", "l": "positive regulation of heptadecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150142", "l": "positive regulation of CD86 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018204", "l": "peptidyl-leucine modification", "d": ["The modification of peptidyl-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035941", "l": "androstenedione secretion", "d": ["The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009926", "l": "auxin polar transport", "d": ["The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072578", "l": "neurotransmitter-gated ion channel clustering", "d": ["The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002103", "l": "endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0140719", "l": "constitutive heterochromatin formation", "d": ["The compaction of chromatin into a conformation that is refactory to transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900988", "l": "ajmaline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ajmaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015853", "l": "adenine transport", "d": ["The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042760", "l": "very long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072381", "l": "positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120077", "l": "angiogenic sprout fusion", "d": ["The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045234", "l": "protein palmitoleylation", "d": ["The covalent attachment of a palmitoleyl group to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900003", "l": "regulation of serine-type endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071873", "l": "response to norepinephrine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140973", "l": "positive regulation of AIM2 inflammasome complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097535", "l": "lymphoid lineage cell migration into thymus", "d": ["The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902294", "l": "cell cycle DNA replication termination", "d": ["Any DNA replication termination that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900762", "l": "averantin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of averantin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035332", "l": "positive regulation of hippo signaling", "d": ["Any process that activates or increases the frequency, rate or extent of hippo signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002207", "l": "gene conversion of immunoglobulin genes involved in immune response", "d": ["The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098870", "l": "action potential propagation", "d": ["The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039524", "l": "suppression by virus of host mRNA processing", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006253", "l": "dCTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048780", "l": "positive regulation of erythrophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of erythrophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046425", "l": "regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010403", "l": "pectic arabinogalactan I metabolic process", "d": ["The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904210", "l": "VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014808", "l": "release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "d": ["The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0106001", "l": "intestinal hexose absorption", "d": ["Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0045621", "l": "positive regulation of lymphocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070987", "l": "error-free translesion synthesis", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072391", "l": "phenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006037", "l": "cell wall chitin metabolic process", "d": ["The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905756", "l": "regulation of primary cell septum biogenesis", "d": ["Any process that modulates the frequency, rate or extent of primary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0098543", "l": "detection of other organism", "d": ["The series of events in which a stimulus from another organism is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902050", "l": "neosartoricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neosartoricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006018", "l": "2-deoxyribose 1-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0007091", "l": "metaphase/anaphase transition of mitotic cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0021548", "l": "pons development", "d": ["The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045991", "l": "carbon catabolite activation of transcription", "d": ["A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061411", "l": "positive regulation of transcription from RNA polymerase II promoter in response to cold", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030711", "l": "positive regulation of border follicle cell delamination", "d": ["Any process that increases the frequency, rate or extent of border cell delamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019918", "l": "peptidyl-arginine methylation, to symmetrical-dimethyl arginine", "d": ["The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902854", "l": "positive regulation of nuclear migration during mitotic telophase", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110041", "l": "regulation of pharynx morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0002474", "l": "antigen processing and presentation of peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003029", "l": "detection of hypoxic conditions in blood by carotid body chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010620", "l": "negative regulation of transcription by transcription factor catabolism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032757", "l": "positive regulation of interleukin-8 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-8 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0001707", "l": "mesoderm formation", "d": ["The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035167", "l": "larval lymph gland hemopoiesis", "d": ["The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097352", "l": "autophagosome maturation", "d": ["Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.63031539877683", "identifiers": [{"i": "GO:0060348", "l": "bone development", "d": ["The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903929", "l": "primary palate development", "d": ["The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045928", "l": "negative regulation of juvenile hormone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070352", "l": "positive regulation of white fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of white fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904777", "l": "negative regulation of protein localization to cell cortex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902981", "l": "synthesis of RNA primer involved in mitotic DNA replication", "d": ["Any synthesis of RNA primer involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903479", "l": "mitotic actomyosin contractile ring assembly actin filament organization", "d": ["Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904825", "l": "protein localization to microtubule plus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075268", "l": "regulation of aecium development", "d": ["Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002447", "l": "eosinophil mediated immunity", "d": ["Any process involved in the carrying out of an immune response by an eosinophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048166", "l": "mature follicle stage", "d": ["The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140904", "l": "cytoophidium organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043619", "l": "regulation of transcription from RNA polymerase II promoter in response to oxidative stress", "d": ["Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031162", "l": "sulfur incorporation into metallo-sulfur cluster", "d": ["The incorporation of exogenous sulfur into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097439", "l": "acquisition of desiccation tolerance", "d": ["The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048215", "l": "positive regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140976", "l": "defense response against perturbation of plasma membrane integrity", "d": ["The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904203", "l": "positive regulation of iodide transport", "d": ["Any process that activates or increases the frequency, rate or extent of iodide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010434", "l": "bract formation", "d": ["The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1902905", "l": "positive regulation of supramolecular fiber organization", "d": ["Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097271", "l": "protein localization to bud neck", "d": ["A process in which a protein is transported to, or maintained at, a location within a cellular bud neck."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007054", "l": "spindle assembly involved in male meiosis I", "d": ["The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032342", "l": "aldosterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032925", "l": "regulation of activin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018898", "l": "2,4-dichlorobenzoate metabolic process", "d": ["The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044208", "l": "'de novo' AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050835", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001097", "l": "laminaritriose transport", "d": ["The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051513", "l": "regulation of monopolar cell growth", "d": ["Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905458", "l": "positive regulation of lymphoid progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036506", "l": "maintenance of unfolded protein", "d": ["Maintaining a protein in an unfolded, soluble state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905386", "l": "positive regulation of protein localization to presynapse", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030505", "l": "inorganic diphosphate transport", "d": ["The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032714", "l": "negative regulation of interleukin-5 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:2001138", "l": "regulation of phospholipid transport", "d": ["Any process that modulates the frequency, rate or extent of phospholipid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1902576", "l": "negative regulation of nuclear cell cycle DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0075509", "l": "endocytosis involved in viral entry into host cell", "d": ["Any endocytosis that is involved in the uptake of a virus into a host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904705", "l": "regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021705", "l": "locus ceruleus formation", "d": ["The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0035930", "l": "corticosteroid hormone secretion", "d": ["The regulated release of any corticosteroid hormone into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0071625", "l": "vocalization behavior", "d": ["The behavior in which an organism produces sounds by a mechanism involving its respiratory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990487", "l": "anaerobic lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901695", "l": "tyramine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tyramine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034352", "l": "positive regulation of glial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034230", "l": "enkephalin processing", "d": ["The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905222", "l": "atrioventricular canal morphogenesis", "d": ["The developmental process by which an atrioventricular canal is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046047", "l": "TTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048318", "l": "axial mesoderm development", "d": ["The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010901", "l": "regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901108", "l": "granaticin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of granaticin."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0036123", "l": "histone H3-K9 dimethylation", "d": ["The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010231", "l": "maintenance of seed dormancy", "d": ["Any process that maintains a seed in a dormant state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021671", "l": "rhombomere 7 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010641", "l": "positive regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019502", "l": "L-proline betaine metabolic process", "d": ["The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0009123", "l": "nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042307", "l": "positive regulation of protein import into nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045898", "l": "regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901934", "l": "bicyclogermacrene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bicyclogermacrene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021894", "l": "cerebral cortex GABAergic interneuron development", "d": ["The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150078", "l": "positive regulation of neuroinflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of neuroinflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.04413933979864", "identifiers": [{"i": "GO:0007018", "l": "microtubule-based movement", "d": ["A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080170", "l": "hydrogen peroxide transmembrane transport", "d": ["The process in which hydrogen peroxide is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0000022", "l": "mitotic spindle elongation", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002924", "l": "negative regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045163", "l": "clustering of voltage-gated potassium channels", "d": ["The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021784", "l": "postganglionic parasympathetic fiber development", "d": ["The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071829", "l": "plasma lipoprotein particle disassembly", "d": ["The disaggregation of a plasma lipoprotein particle into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045053", "l": "protein retention in Golgi apparatus", "d": ["The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.70470389845471", "identifiers": [{"i": "GO:0016064", "l": "immunoglobulin mediated immune response", "d": ["An immune response mediated by immunoglobulins, whether cell-bound or in solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071995", "l": "phytochelatin import into vacuole", "d": ["The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097601", "l": "retina blood vessel maintenance", "d": ["A retina homeostatic process preventing the degeneration of a retina blood vessel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035458", "l": "cellular response to interferon-beta", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110074", "l": "positive regulation of apical constriction involved in ventral furrow formation", "d": ["Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001988", "l": "positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903331", "l": "positive regulation of iron-sulfur cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052801", "l": "bicyclic nitroimidazole metabolic process", "d": ["The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009556", "l": "microsporogenesis", "d": ["The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010763", "l": "positive regulation of fibroblast migration", "d": ["Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000785", "l": "regulation of autophagosome assembly", "d": ["Any process that modulates the frequency, rate or extent of autophagosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903255", "l": "hercynylselenocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hercynylselenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051544", "l": "positive regulation of elastin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.419567574264811", "identifiers": [{"i": "GO:0048666", "l": "neuron development", "d": ["The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904368", "l": "regulation of sclerenchyma cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046012", "l": "positive regulation of oskar mRNA translation", "d": ["Any process that activates or increases the frequency, rate or extent of oskar mRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002843", "l": "regulation of tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901955", "l": "negative regulation of retrograde dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044097", "l": "secretion by the type IV secretion system", "d": ["The controlled release of proteins or DNA by a cell, via the type IV secretion system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044315", "l": "protein secretion by the type VII secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003041", "l": "excitation of vasomotor center by carotid body chemoreceptor signaling", "d": ["The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060330", "l": "regulation of response to type II interferon", "d": ["Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900170", "l": "negative regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0022405", "l": "hair cycle process", "d": ["A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099640", "l": "axo-dendritic protein transport", "d": ["The directed movement of proteins along microtubules in neuron projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905310", "l": "regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1900619", "l": "acetate ester metabolic process", "d": ["The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046335", "l": "ethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034553", "l": "mitochondrial respiratory chain complex II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042953", "l": "lipoprotein transport", "d": ["The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046339", "l": "diacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001313", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process", "d": ["The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072154", "l": "proximal convoluted tubule segment 1 cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001705", "l": "ectoderm formation", "d": ["The formation of ectoderm during gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.422285095499703", "identifiers": [{"i": "GO:0048864", "l": "stem cell development", "d": ["The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046318", "l": "negative regulation of glucosylceramide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000024", "l": "regulation of leaf development", "d": ["Any process that modulates the frequency, rate or extent of leaf development."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.85632607702658", "identifiers": [{"i": "GO:0099537", "l": "trans-synaptic signaling", "d": ["Cell-cell signaling in either direction across the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905245", "l": "regulation of aspartic-type peptidase activity", "d": ["Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018873", "l": "atrazine metabolic process", "d": ["The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075000", "l": "response to host osmotic environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000161", "l": "regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903853", "l": "regulation of stress response to copper ion", "d": ["Any process that modulates the frequency, rate or extent of stress response to copper ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090177", "l": "establishment of planar polarity involved in neural tube closure", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0141060", "l": "disruption of anatomical structure in another organism", "d": ["The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098995", "l": "disruption by virus of host envelope lipopolysaccharide during virus entry", "d": ["The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042822", "l": "pyridoxal phosphate metabolic process", "d": ["The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0016073", "l": "snRNA metabolic process", "d": ["The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031296", "l": "B cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, 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spleen, and mucosal-associated lymphoid tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061454", "l": "release of sequestered calcium ion into cytosol by Golgi", "d": ["The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009631", "l": "cold acclimation", "d": ["Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0043633", "l": "polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080024", "l": "indolebutyric acid metabolic process", "d": ["The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046072", "l": "dTDP metabolic process", "d": ["The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140646", "l": "negative regulation of pre-B cell receptor expression", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903675", "l": "negative regulation of cap-dependent translational initiation", "d": ["Any process that 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901285", "l": "5,6,7,8-tetrahydromethanopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033231", "l": "carbohydrate export", "d": ["The directed movement of carbohydrates out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900315", "l": "regulation of maltopentaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltopentaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0060415", "l": "muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000758", "l": "agglutination involved in conjugation with mutual genetic exchange", "d": ["The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903518", "l": "positive regulation of single strand break repair", "d": ["Any process that activates or increases the frequency, rate or extent of single strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034180", "l": "negative regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901412", "l": "positive regulation of tetrapyrrole biosynthetic process from glutamate", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0021602", "l": "cranial nerve morphogenesis", "d": ["The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000124", "l": "regulation of endocannabinoid signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021667", "l": "rhombomere 6 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045850", "l": "positive regulation of nurse cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033393", "l": "homogalacturonan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0031109", "l": "microtubule polymerization or depolymerization", "d": ["Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061862", "l": "cellular response to differentiation-inducing factor 2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.671314681979048", "identifiers": [{"i": "GO:0030098", "l": "lymphocyte differentiation", "d": ["The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042067", "l": "establishment of ommatidial planar polarity", "d": ["The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000584", "l": "negative regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045627", "l": "positive regulation of T-helper 1 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.508857221095191", "identifiers": [{"i": "GO:0007010", "l": "cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent 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"l": "deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007120", "l": "axial cellular bud site selection", "d": ["The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901394", "l": "positive regulation of transforming growth factor beta1 activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032287", "l": "peripheral nervous system myelin maintenance", "d": ["The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070535", "l": "histone H2A K63-linked ubiquitination", "d": ["A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072567", "l": "chemokine (C-X-C motif) ligand 2 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061227", "l": "pattern specification involved in mesonephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0051905", "l": "establishment of pigment granule localization", "d": ["The directed movement of a pigment granule to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010269", "l": "response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018103", "l": "protein C-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or 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A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905346", "l": "protein localization to cleavage furrow rim", "d": ["A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900200", "l": "mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any mesenchymal cell apoptotic process that is involved in metanephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905848", "l": "positive regulation of cellular response to oxidopamine", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0090627", "l": "plant epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071810", "l": "regulation of fever generation by regulation of prostaglandin secretion", "d": ["Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990874", "l": "vascular associated smooth muscle cell proliferation", "d": ["The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039021", "l": "pronephric glomerulus development", "d": ["The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904371", "l": "negative regulation of protein localization to actin cortical patch", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051563", "l": "smooth endoplasmic reticulum calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0098722", "l": "asymmetric stem cell division", "d": ["Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060471", "l": "cortical granule exocytosis", "d": ["The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048785", "l": "hatching gland development", "d": ["The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048389", "l": "intermediate mesoderm development", "d": ["The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903679", "l": "positive regulation of cap-independent translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903316", "l": "positive regulation of nitrogen cycle metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901511", "l": "(-)-microperfuranone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001031", "l": "positive regulation of cellular glucuronidation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular glucuronidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042996", "l": "regulation of Golgi to plasma membrane protein transport", "d": ["Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098776", "l": "protein transport across the cell outer membrane", "d": ["The directed movement of proteins across the cell outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901620", "l": "regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110015", "l": "positive regulation of elastin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006190", "l": "inosine salvage", "d": ["Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006604", "l": "phosphoarginine metabolic process", "d": ["The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900263", "l": "negative regulation of DNA-directed DNA polymerase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035168", "l": "larval lymph gland hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000773", "l": "negative regulation of cellular senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0007289", "l": "spermatid nucleus differentiation", "d": ["The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140285", "l": "endosome fission", "d": ["The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990739", "l": "granulosa cell proliferation", "d": ["The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009822", "l": "alkaloid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904905", "l": "negative regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1900274", "l": "regulation of phospholipase C activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase C activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019518", "l": "L-threonine catabolic process to glycine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099155", "l": "synaptic transmission, noradrenergic", "d": ["The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032230", "l": "positive regulation of synaptic transmission, GABAergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904058", "l": "positive regulation of sensory perception of pain", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of pain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002305", "l": "CD8-positive, gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030494", "l": "bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1905725", "l": "protein localization to microtubule end", "d": ["A process in which a protein is transported to, or maintained in, a location at a microtubule end."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0045472", "l": "response to ether", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902088", "l": "plant-type cell wall loosening involved in abscission", "d": ["Any plant-type cell wall loosening that is involved in abscission."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900123", "l": "regulation of nodal receptor complex assembly", "d": ["Any process that modulates the frequency, rate or extent of nodal receptor complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010515", "l": "negative regulation of induction of conjugation with cellular fusion", "d": ["Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000362", "l": "negative regulation of prostaglandin-E synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902834", "l": "regulation of proline import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of proline import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904811", "l": "positive regulation of dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015676", "l": "vanadium ion transport", "d": ["The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030309", "l": "poly-N-acetyllactosamine metabolic process", "d": ["The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006057", "l": "mannoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0006941", "l": "striated muscle contraction", "d": ["A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010372", "l": "positive regulation of gibberellin biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0106049", "l": "regulation of cellular response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001916", "l": "positive regulation of T cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001109", "l": "regulation of lens epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048368", "l": "lateral mesoderm development", "d": ["The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903271", "l": "negative regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900870", "l": "tatiopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tatiopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035504", "l": "regulation of myosin light chain kinase activity", "d": ["Any process that modulates the frequency, rate or extent of myosin light chain kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061757", "l": "leukocyte adhesion to arterial endothelial cell", "d": ["The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045151", "l": "acetoin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043968", "l": "histone H2A acetylation", "d": ["The modification of histone H2A by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060404", "l": "axonemal microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903200", "l": "positive regulation of L-dopa decarboxylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900025", "l": "negative regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042817", "l": "pyridoxal metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905189", "l": "regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061235", "l": "mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007503", "l": "fat body development", "d": ["The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046438", "l": "D-cysteine metabolic process", "d": ["The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902208", "l": "regulation of bacterial-type flagellum assembly", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032539", "l": "negative regulation of host-seeking behavior", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0007063", "l": "regulation of sister chromatid cohesion", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid cohesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900333", "l": "regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061125", "l": "negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009638", "l": "phototropism", "d": ["The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048298", "l": "positive regulation of isotype switching to IgA isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009179", "l": "purine ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019415", "l": "acetate biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045112", "l": "integrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0000377", "l": "RNA splicing, via transesterification reactions with bulged adenosine as nucleophile", "d": ["Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903840", "l": "response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031340", "l": "positive regulation of vesicle fusion", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061119", "l": "regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061511", "l": "centriole elongation", "d": ["The centrosome organization process by which a centriole increases in length as part of the process of replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.25778018697109", "identifiers": [{"i": "GO:0010001", "l": "glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0007368", "l": "determination of left/right symmetry", "d": ["The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0000122", "l": "negative regulation of transcription by RNA polymerase II", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035384", "l": "thioester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072135", "l": "kidney mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015967", "l": "diadenosine tetraphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0022030", "l": "telencephalon glial cell migration", "d": ["The orderly movement of glial cells through the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060115", "l": "vestibular receptor cell fate commitment", "d": ["The process in which a cell becomes committed to become a vestibular receptor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002513", "l": "tolerance induction to self antigen", "d": ["Tolerance induction directed at self antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090308", "l": "regulation of DNA methylation-dependent heterochromatin formation", "d": ["Any process that modulates the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010363", "l": "regulation of plant-type hypersensitive response", "d": ["Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140746", "l": "siRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000962", "l": "positive regulation of mitochondrial RNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034969", "l": "histone arginine methylation", "d": ["The modification of a histone by addition of a methyl group to an arginine residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045147", "l": "regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070793", "l": "regulation of conidiophore development", "d": ["Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039637", "l": "catabolism by virus of host DNA", "d": ["The breakdown of host DNA, deoxyribonucleic acid, by a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990344", "l": "secondary cell septum biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070509", "l": "calcium ion import", "d": ["The directed movement of calcium ions into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048300", "l": "negative regulation of isotype switching to IgD isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016476", "l": "regulation of embryonic cell shape", "d": ["Any process that modulates the surface configuration of an embryonic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903716", "l": "guanine transmembrane transport", "d": ["The process in which guanine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003043", "l": "vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900107", "l": "regulation of nodal signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of nodal signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902642", "l": "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033080", "l": "immature T cell proliferation in thymus", "d": ["The expansion of an immature T cell population by cell division in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990962", "l": "xenobiotic transport across blood-brain barrier", "d": ["The directed movement of a xenobiotic through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032072", "l": "regulation of restriction endodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019596", "l": "mandelate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0071466", "l": "cellular response to xenobiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035510", "l": "DNA dealkylation", "d": ["The removal of an alkyl group from one or more nucleotides within an DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019640", "l": "glucuronate catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070836", "l": "caveola assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051941", "l": "regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900039", "l": "positive regulation of cellular response to hypoxia", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060526", "l": "prostate glandular acinus morphogenesis", "d": ["The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042758", "l": "long-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090228", "l": "positive regulation of red or far-red light signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990553", "l": "mitochondrial 5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046680", "l": "response to DDT", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001295", "l": "malonyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061365", "l": "positive regulation of triglyceride lipase activity", "d": ["Any process that increases the activity of triglyceride lipase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900156", "l": "positive regulation of bone trabecula formation", "d": ["Any process that activates or increases the frequency, rate or extent of bone trabecula formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1990173", "l": "protein localization to nucleoplasm", "d": ["A process in which a protein is transported to, or maintained in, a location within the nucleoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044489", "l": "negative regulation of voltage-gated sodium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045466", "l": "R7 cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039710", "l": "cytoplasmic icosahedral capsid assembly", "d": ["The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060737", "l": "prostate gland morphogenetic growth", "d": ["The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033473", "l": "indoleacetic acid conjugate metabolic process", "d": ["The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900695", "l": "regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902782", "l": "response to decane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903951", "l": "positive regulation of AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of AV node cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140025", "l": "contractile vacuole tethering involved in discharge", "d": ["The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904452", "l": "negative regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055068", "l": "cobalt ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033147", "l": "negative regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0140448", "l": "signaling receptor ligand precursor processing", "d": ["The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060904", "l": "regulation of protein folding in endoplasmic reticulum", "d": ["Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.25778018697109", "identifiers": [{"i": "GO:0002573", "l": "myeloid leukocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031584", "l": "activation of phospholipase D activity", "d": ["Any process that initiates the activity of inactive phospholipase D."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009901", "l": "anther dehiscence", "d": ["The dehiscence of an anther to release the pollen grains contained within it."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904044", "l": "response to aldosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019276", "l": "UDP-N-acetylgalactosamine metabolic process", "d": ["The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904321", "l": "response to forskolin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014741", "l": "negative regulation of muscle hypertrophy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002711", "l": "positive regulation of T cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035350", "l": "FAD transmembrane transport", "d": ["The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070600", "l": "fungal-type cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050966", "l": "detection of mechanical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098716", "l": "nickel cation import across plasma membrane", "d": ["The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1901020", "l": "negative regulation of calcium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061121", "l": "regulation of positive chemotaxis to cAMP by DIF-2", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903808", "l": "L-tyrosine import across plasma membrane", "d": ["The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.327366391955856", "identifiers": [{"i": "GO:0007059", "l": "chromosome segregation", "d": ["The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000129", "l": "negative regulation of octopamine signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905587", "l": "positive regulation of outer hair cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085030", "l": "symbiotic process benefiting host", "d": ["A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070978", "l": "voltage-gated calcium channel complex assembly", "d": ["Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036331", "l": "avascular cornea development in camera-type eye", "d": ["The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000670", "l": "positive regulation of dendritic cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:2000146", "l": "negative regulation of cell motility", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0006576", "l": "biogenic amine metabolic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002785", "l": "negative regulation of antimicrobial peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070453", "l": "regulation of heme biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000844", "l": "negative regulation of testosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032831", "l": "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904512", "l": "regulation of initiation of premeiotic DNA replication", "d": ["Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042117", "l": "monocyte activation", "d": ["The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900722", "l": "regulation of protein adenylylation", "d": ["Any process that modulates the frequency, rate or extent of protein adenylylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904727", "l": "negative regulation of replicative senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031126", "l": "sno(s)RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902416", "l": "positive regulation of mRNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070203", "l": "regulation of establishment of protein localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0006650", "l": "glycerophospholipid metabolic process", "d": ["The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0032609", "l": "type II interferon production", "d": ["The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032887", "l": "regulation of spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097167", "l": "circadian regulation of translation", "d": ["Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002655", "l": "regulation of tolerance induction to nonself antigen", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000411", "l": "positive regulation of transcription by galactose", "d": ["Any process involving galactose that activates or increases the rate of transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0075214", "l": "spore encystment", "d": ["The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.768237641259716", "identifiers": [{"i": "GO:0030431", "l": "sleep", "d": ["Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044575", "l": "cellulosome assembly", "d": ["The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900533", "l": "palmitic acid metabolic process", "d": ["The chemical reactions and pathways involving palmitic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070169", "l": "positive regulation of biomineral tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900433", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0043114", "l": "regulation of vascular permeability", "d": ["Any process that modulates the extent to which blood vessels can be pervaded by fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0046131", "l": "pyrimidine ribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035340", "l": "inosine transport", "d": ["The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905947", "l": "positive regulation of response to calcium ion", "d": ["Any process that activates or increases the frequency, rate or extent of response to calcium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036489", "l": "neuromelanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neuromelanin. 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The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0048449", "l": "floral organ formation", "d": ["The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010887", "l": "negative regulation of cholesterol storage", "d": ["Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044574", "l": "starch utilization system complex assembly", "d": ["The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001831", "l": "trophectodermal cellular morphogenesis", "d": ["The morphogenesis of trophectoderm cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051158", "l": "L-arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032528", "l": "microvillus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051630", "l": "acetylcholine uptake", "d": ["The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904431", "l": "positive regulation of t-circle formation", "d": ["Any process that activates or increases the frequency, rate or extent of t-circle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010052", "l": "guard cell differentiation", "d": ["The process in which a guard mother cell acquires the specialized features of a guard cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0050670", "l": "regulation of lymphocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000907", "l": "negative regulation of glucomannan catabolic process", "d": ["Any process that stops, prevents or reduces 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{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905956", "l": "positive regulation of endothelial tube morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990687", "l": "endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902037", "l": "negative regulation of hematopoietic stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099145", "l": "regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane", "d": ["Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903930", "l": "regulation of pyrimidine-containing compound salvage", "d": ["Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045929", "l": "positive regulation of juvenile hormone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044794", "l": "positive regulation by host of viral process", "d": ["A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901535", "l": "regulation of DNA demethylation", "d": ["Any process that modulates the frequency, rate or extent of DNA demethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903653", "l": "modulation by symbiont of host cell motility", "d": ["Modulation of host cell motility by a symbiont of that host."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.367368887635308", "identifiers": [{"i": "GO:0010959", "l": "regulation of metal ion transport", "d": ["Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062084", "l": "regulation of capsule polysaccharide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150091", "l": "multiple spine synapse organization, multiple dendrites", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048374", "l": "regulation of lateral mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002097", "l": "tRNA wobble base modification", "d": ["The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061853", "l": "regulation of neuroblast migration", "d": ["Any process that modulates the frequency, rate or extent of neuroblast migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072747", "l": "cellular response to chloramphenicol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099040", "l": "ceramide translocation", "d": ["The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043634", "l": "polyadenylation-dependent ncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033386", "l": "geranylgeranyl diphosphate biosynthetic process", "d": ["The chemical 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extent of mitotic cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060363", "l": "cranial suture morphogenesis", "d": ["The process in which any suture between cranial bones is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043095", "l": "regulation of GTP cyclohydrolase I activity", "d": ["Any process that modulates the activity of the enzyme GTP cyclohydrolase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009186", "l": "deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044616", "l": "modulation of relaxation of muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of muscle in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061198", "l": "fungiform papilla formation", "d": ["The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0009838", "l": "abscission", "d": ["The controlled shedding of a body part."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019472", "l": "4-hydroxyproline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099150", "l": "regulation of postsynaptic specialization assembly", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072124", "l": "regulation of glomerular mesangial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097473", "l": "retinal rod cell apoptotic process", "d": ["Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902165", "l": "regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019701", "l": "peptidyl-arginine N5-methylation", "d": ["The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048874", "l": "host-mediated regulation of intestinal microbiota composition", "d": ["The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046843", "l": "dorsal appendage formation", "d": ["Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.456983445895961", "identifiers": [{"i": "GO:0044237", "l": "cellular metabolic process", "d": ["The chemical reactions and pathways by which individual cells transform chemical substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021719", "l": "superior olivary nucleus morphogenesis", "d": ["The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071451", "l": "cellular response to superoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050843", "l": "S-adenosylmethionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044644", "l": "envenomation resulting in negative regulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900819", "l": "orlandin metabolic process", "d": ["The chemical reactions and pathways involving orlandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0009438", "l": "methylglyoxal metabolic process", "d": ["The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070649", "l": "formin-nucleated actin cable assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071712", "l": "ER-associated misfolded protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010793", "l": "regulation of mRNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035126", "l": "post-embryonic genitalia morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900835", "l": "negative regulation of emericellin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904336", "l": "negative regulation of ductus arteriosus closure", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031159", "l": "positive regulation of aggregate size involved in sorocarp development", "d": ["Any process that increases the size of the aggregate formed during sorocarp formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046641", "l": "positive regulation of alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900896", "l": "regulation of heptadecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042250", "l": "maintenance of polarity of embryonic epithelium", "d": ["The maintenance of an established polarized embryonic epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072117", "l": "head kidney formation", "d": ["The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905043", "l": "positive regulation of epithelium regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelium regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075194", "l": "positive regulation of haustorium mother cell formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051484", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904867", "l": "protein localization to Cajal body", "d": ["A process in which a protein is transported to, or maintained in, a location within a Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0110111", "l": "negative regulation of animal organ morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060940", "l": "epithelial to mesenchymal transition involved in cardiac fibroblast development", "d": ["A transition where an epicardial cell loses apical/basolateral polarity, 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018072", "l": "peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid", "d": ["The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006188", "l": "IMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140544", "l": "septin collar organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905876", "l": "positive regulation of postsynaptic density organization", "d": ["Any process that activates or increases the frequency, rate or extent of postsynaptic density organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008070", "l": "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded", "d": ["Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0030222", "l": "eosinophil differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060816", "l": "random inactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032707", "l": "negative regulation of interleukin-23 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000583", "l": "regulation of platelet-derived growth factor receptor-alpha signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0035120", "l": "post-embryonic appendage morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of 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An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035288", "l": "anterior head segmentation", "d": ["Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0039693", "l": "viral DNA genome replication", "d": ["The replication of a viral DNA genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001867", "l": "complement activation, lectin pathway", "d": ["Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010322", "l": "regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021541", "l": "ammon gyrus development", "d": ["The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0002367", "l": "cytokine production involved in immune response", "d": ["The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0086066", "l": "atrial cardiac muscle cell to AV node cell communication", "d": ["The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.747250640783442", "identifiers": [{"i": "GO:0003006", "l": "developmental process involved in reproduction", "d": ["A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007287", "l": "Nebenkern assembly", "d": ["Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901504", "l": "triazole transport", "d": ["The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097231", "l": "cell motility in response to calcium ion", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120314", "l": "negative regulation of oocyte karyosome formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900569", "l": "chanoclavine-I aldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0033363", "l": "secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019427", "l": "acetyl-CoA biosynthetic process from acetate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0030584", "l": "sporocarp development", "d": ["The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905229", "l": "cellular response to thyrotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0015693", "l": "magnesium ion transport", "d": ["The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060426", "l": "lung vasculature development", "d": ["The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110102", "l": "ribulose bisphosphate carboxylase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010396", "l": "rhamnogalacturonan II metabolic process", "d": ["The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902083", "l": "negative regulation of peptidyl-cysteine S-nitrosylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048050", "l": "post-embryonic eye morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. 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Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1905933", "l": "regulation of cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902112", "l": "cellular response to diethyl maleate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0008344", "l": "adult locomotory behavior", "d": ["Locomotory behavior in a fully developed and mature organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903741", "l": "negative regulation of phosphatidate phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014045", "l": "establishment of endothelial blood-brain barrier", "d": ["Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032456", "l": "endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010501", "l": "RNA secondary structure unwinding", "d": ["The process in which a secondary structure of RNA are broken or 'melted'."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034759", "l": "regulation of iron ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019633", "l": "shikimate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.697068671355382", "identifiers": [{"i": "GO:0071824", "l": "protein-DNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900788", "l": "pseurotin A metabolic process", "d": ["The chemical reactions and pathways involving pseurotin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035191", "l": "nuclear axial expansion", "d": ["The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0045939", "l": "negative regulation of steroid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048934", "l": "peripheral nervous system neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900677", "l": "positive regulation of F-9775B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098003", "l": "viral tail assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016446", "l": "somatic hypermutation of immunoglobulin genes", "d": ["Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051475", "l": "glucosylglycerol transmembrane transport", "d": ["The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006195", "l": "purine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021838", "l": "motogenic signaling involved in interneuron migration from the subpallium to the cortex", "d": ["The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032781", "l": "positive regulation of ATP-dependent activity", "d": ["Any process that activates or increases the rate of an ATP-dependent activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039012", "l": "pronephric sinus development", "d": ["The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080112", "l": "seed growth", "d": ["The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045835", "l": "negative regulation of meiotic nuclear division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0070127", "l": "tRNA aminoacylation for mitochondrial protein translation", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0035787", "l": "cell migration involved in kidney development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090160", "l": "Golgi to lysosome transport", "d": ["The directed movement of substances from the Golgi to lysosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905764", "l": "regulation of protection from non-homologous end joining at telomere", "d": ["Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002268", "l": "follicular dendritic cell differentiation", "d": ["The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0002344", "l": "B cell affinity maturation", "d": ["The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090630", "l": "activation of GTPase activity", "d": ["Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060094", "l": "positive regulation of synaptic transmission, glycinergic", "d": ["Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0071027", "l": "nuclear RNA surveillance", "d": ["A process that identifies and degrades defective or aberrant RNAs within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001136", "l": "negative regulation of endocytic recycling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0005990", "l": "lactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0071684", "l": "organism emergence from protective structure", "d": ["The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051643", "l": "endoplasmic reticulum localization", "d": ["Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904073", "l": "regulation of trophectodermal cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003215", "l": "cardiac right ventricle morphogenesis", "d": ["The process in which the right cardiac ventricle is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007406", "l": "negative regulation of neuroblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0019336", "l": "phenol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035271", "l": "ring gland development", "d": ["Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900111", "l": "positive regulation of histone H3-K9 dimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905327", "l": "tracheoesophageal septum formation", "d": ["The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030417", "l": "nicotianamine metabolic process", "d": ["The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014735", "l": "regulation of muscle atrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle atrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001812", "l": "positive regulation of type I hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048939", "l": "anterior lateral line nerve glial cell development", "d": ["The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042147", "l": "retrograde transport, endosome to Golgi", "d": ["The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099121", "l": "fungal sorus development", "d": ["The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009989", "l": "cell-matrix recognition", "d": ["Cell recognition that involves the interaction of the cell with the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046168", "l": "glycerol-3-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:1900378", "l": "positive regulation of secondary metabolite biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905156", "l": "negative regulation of photosynthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0050961", "l": "detection of temperature stimulus involved in sensory perception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051394", "l": "regulation of nerve growth factor receptor activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010047", "l": "fruit dehiscence", "d": ["The process leading to the spontaneous opening of the fruit permitting the escape of seeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045475", "l": "locomotor rhythm", "d": ["The rhythm of the locomotor activity of an organism during its 24 hour activity cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0016115", "l": "terpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032007", "l": "negative regulation of TOR signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072560", "l": "type B pancreatic cell maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007510", "l": "cardioblast cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032736", "l": "positive regulation of interleukin-13 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-13 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090611", "l": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.464570793274198", "identifiers": [{"i": "GO:0006915", "l": "apoptotic process", "d": ["A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000067", "l": "regulation of root morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of root morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000058", "l": "regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002276", "l": "basophil activation involved in immune response", "d": ["A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.306098259633643", "identifiers": [{"i": "GO:0140029", "l": "exocytic process", "d": ["The cellular processes that contribute to exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052799", "l": "coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051629", "l": "inhibition of epinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of epinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048728", "l": "proboscis development", "d": ["The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060777", "l": "compound leaf morphogenesis", "d": ["The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045023", "l": "G0 to G1 transition", "d": ["The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0085034", "l": "symbiont-mediated suppression of host canonical NF-kappaB cascade", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a canonical NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0009071", "l": "serine family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0052559", "l": "induction by symbiont of host immune response", "d": ["Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032760", "l": "positive regulation of tumor necrosis factor production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075279", "l": "uredinium development", "d": ["The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018285", "l": "iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide", "d": ["The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007492", "l": "endoderm development", "d": ["The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003045", "l": "regulation of systemic arterial blood pressure by physical factors", "d": ["The regulation of blood pressure mediated by detection of forces within the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061288", "l": "mesonephric capsule specification", "d": ["The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090054", "l": "regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that modulates the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070926", "l": "regulation of ATP:ADP antiporter activity", "d": ["Any process that modulates the activity of an ATP:ADP antiporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090182", "l": "regulation of secretion of lysosomal enzymes", "d": ["Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990181", "l": "acetyl-CoA biosynthetic process from pantothenate", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090213", "l": "regulation of radial pattern formation", "d": ["Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901811", "l": "beta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034349", "l": "glial cell apoptotic process", "d": ["Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090071", "l": "negative regulation of ribosome biogenesis", "d": ["Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901151", "l": "vistamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vistamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071657", "l": "positive regulation of granulocyte colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032492", "l": "detection of molecule of oomycetes origin", "d": ["The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0042703", "l": "menstruation", "d": ["The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006867", "l": "asparagine transport", "d": ["The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903111", "l": "negative regulation of single-strand break repair via homologous recombination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035903", "l": "cellular response to immobilization stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0046323", "l": "glucose import", "d": ["The directed movement of the hexose monosaccharide glucose into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001015", "l": "snoRNA transcription by RNA polymerase II", "d": ["The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070549", "l": "siRNA-mediated gene silencing by inhibition of translation", "d": ["An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003237", "l": "sinus venosus formation", "d": ["The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0033059", "l": "cellular pigmentation", "d": ["The deposition or aggregation of coloring matter in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035203", "l": "regulation of lamellocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031407", "l": "oxylipin metabolic process", "d": ["The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080151", "l": "positive regulation of salicylic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098751", "l": "bone cell development", "d": ["The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110075", "l": "regulation of ferroptosis", "d": ["Any process that modulates the frequency, rate or extent of ferroptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030947", "l": "regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019328", "l": "anaerobic gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035783", "l": "CD4-positive, alpha-beta T cell costimulation", "d": ["The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0021924", "l": "cell proliferation in external granule layer", "d": ["The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0060419", "l": "heart growth", "d": ["The increase in size or mass of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000964", "l": "mitochondrial RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060618", "l": "nipple development", "d": ["The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071767", "l": "mycolic acid metabolic process", "d": ["The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051296", "l": "establishment of meiotic spindle orientation", "d": ["Any process that set the alignment of meiotic spindle relative to other cellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905859", "l": "negative regulation of heparan sulfate proteoglycan binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009600", "l": "detection of nematode", "d": ["The series of events in which a stimulus from a nematode is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904314", "l": "cellular response to methamphetamine hydrochloride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903687", "l": "negative regulation of border follicle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010171", "l": "body morphogenesis", "d": ["The process in which the anatomical structures of the soma are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044069", "l": "modulation by symbiont of host anion transport", "d": ["The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097745", "l": "mitochondrial tRNA 5'-end processing", "d": ["The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901600", "l": "strigolactone metabolic process", "d": ["The chemical reactions and pathways involving strigolactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900038", "l": "negative regulation of cellular response to hypoxia", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045068", "l": "negative extrathymic T cell selection", "d": ["The process of elimination of extrathymically maturing T cells which react strongly with self-antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120265", "l": "negative regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0000087", "l": "mitotic M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903680", "l": "acinar cell of sebaceous gland differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036346", "l": "cellular response to L-cysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042220", "l": "response to cocaine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048623", "l": "seed germination on parent plant", "d": ["The process in which a seed germinates before being shed from the parent plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061046", "l": "regulation of branching involved in lung morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061588", "l": "calcium activated phospholipid scrambling", "d": ["The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0002335", "l": "mature B cell differentiation", "d": ["The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021758", "l": "putamen development", "d": ["The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0061053", "l": "somite development", "d": ["The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905744", "l": "regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.16494433675436", "identifiers": [{"i": "GO:0008217", "l": "regulation of blood pressure", "d": ["Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010228", "l": "vegetative to reproductive phase transition of meristem", "d": ["The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010022", "l": "meristem determinacy", "d": ["The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110039", "l": "positive regulation of nematode male tail tip morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002677", "l": "negative regulation of chronic inflammatory response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905307", "l": "response to miconazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:2000966", "l": "regulation of cell wall polysaccharide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018258", "l": "protein O-linked glycosylation via hydroxyproline", "d": ["The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045628", "l": "regulation of T-helper 2 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080168", "l": "abscisic acid transport", "d": ["The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904624", "l": "regulation of glycine secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900082", "l": "negative regulation of arginine catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071993", "l": "phytochelatin transport", "d": ["The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044652", "l": "adhesion of symbiont to host endothelial cell", "d": ["The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000739", "l": "regulation of mesenchymal stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072206", "l": "metanephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002527", "l": "vasodilation involved in acute inflammatory response", "d": ["An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060276", "l": "maintenance of stationary phase in response to toxin", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902061", "l": "betaine aldehyde metabolic process", "d": ["The chemical reactions and pathways involving betaine aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018884", "l": "carbazole metabolic process", "d": ["The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007493", "l": "endodermal cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042102", "l": "positive regulation of T cell proliferation", "d": ["Any process that activates or increases the rate or extent of T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016267", "l": "O-glycan processing, core 1", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902615", "l": "immune response involved in response to exogenous dsRNA", "d": ["Any immune response that is involved in response to exogenous dsRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099506", "l": "synaptic vesicle transport along actin filament", "d": ["The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901190", "l": "regulation of formation of translation initiation ternary complex", "d": ["Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120306", "l": "cellular response to actin cytoskeletal stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905006", "l": "negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061391", "l": "negative regulation of direction of cell growth", "d": ["Any process that decreases the direction of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006703", "l": "estrogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141034", "l": "perturbation by symbiont of host actin cytoskeleton via inhibition of actin polymerization", "d": ["The process in which an organism effects a change that disrupts the host actin cytoskeleton by inhibiting host actin from polymerizing. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0070828", "l": "heterochromatin organization", "d": ["Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046653", "l": "tetrahydrofolate metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0051339", "l": "regulation of lyase activity", "d": ["Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006932", "l": "substrate-dependent cell migration, cell contraction", "d": ["The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0035113", "l": "embryonic appendage morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097578", "l": "sequestering of copper ion", "d": ["The process of binding or confining copper ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902824", "l": "positive regulation of late endosome to lysosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903859", "l": "regulation of dendrite extension", "d": ["Any process that modulates the frequency, rate or extent of dendrite extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901417", "l": "negative regulation of response to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140846", "l": "positive regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072356", "l": "chromosome passenger complex localization to kinetochore", "d": ["A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016480", "l": "negative regulation of transcription by RNA polymerase III", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0039514", "l": "disruption by virus of host JAK-STAT cascade", "d": ["A process in which a virus interferes with, inhibits or stops the JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014906", "l": "myotube cell development involved in skeletal muscle regeneration", "d": ["The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140635", "l": "neutrophil dispersal", "d": ["The movement of a neutrophil away from the site of wound or infection following its initial migration to the site."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903765", "l": "negative regulation of potassium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904849", "l": "positive regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070902", "l": "mitochondrial tRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051867", "l": "general adaptation syndrome, behavioral process", "d": ["The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075313", "l": "basidium development", "d": ["The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016255", "l": "attachment of GPI anchor to protein", "d": ["A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050651", "l": "dermatan sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042904", "l": "9-cis-retinoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904349", "l": "positive regulation of small intestine smooth muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046136", "l": "positive regulation of vitamin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0006521", "l": "regulation of cellular amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052078", "l": "symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway", "d": ["A process in which a virus interferes with, inhibits or disrupts a PAMP signaling pathway in its host organism, initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900277", "l": "negative regulation of proteinase activated receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140215", "l": "regulation of D-aspartate import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990678", "l": "histone H4-K16 deacetylation", "d": ["The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051501", "l": "diterpene phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071357", "l": "cellular response to type I interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140040", "l": "mitochondrial polycistronic RNA processing", "d": ["The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006385", "l": "transcription elongation by RNA polymerase III", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021726", "l": "lateral reticular nucleus development", "d": ["The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036390", "l": "pre-replicative complex assembly involved in bacterial-type DNA replication", "d": ["The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044533", "l": "positive regulation of apoptotic process in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.839369058966383", "identifiers": [{"i": "GO:0008219", "l": "cell death", "d": ["Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035441", "l": "cell migration involved in vasculogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160078", "l": "negative regulation of lipid droplet fusion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipid droplet fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905791", "l": "negative regulation of mechanosensory behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038056", "l": "negative regulation of BMP signaling pathway by negative regulation of BMP secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098696", "l": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.064426759960739", "identifiers": [{"i": "GO:0007346", "l": "regulation of mitotic cell cycle", "d": ["Any process that modulates the rate or extent of progress through the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.541206332392782", "identifiers": [{"i": "GO:0002253", "l": "activation of immune response", "d": ["Any process that initiates an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051913", "l": "regulation of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0020027", "l": "hemoglobin metabolic process", "d": ["The chemical reactions and pathways involving hemoglobin, including its uptake and utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0006898", "l": "receptor-mediated endocytosis", "d": ["An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0090306", "l": "meiotic spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2001308", "l": "gliotoxin metabolic process", "d": ["The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0070231", "l": "T cell apoptotic process", "d": ["Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160069", "l": "surfactant secretion", "d": ["The regulated release of surfactant by a cell or tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000977", "l": "regulation of forebrain neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of forebrain neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0051495", "l": "positive regulation of cytoskeleton organization", "d": ["Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052697", "l": "xenobiotic glucuronidation", "d": ["The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990375", "l": "baculum development", "d": ["The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0052173", "l": "response to defenses of other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901380", "l": "negative regulation of potassium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0009106", "l": "lipoate metabolic process", "d": ["The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045641", "l": "negative regulation of basophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106040", "l": "regulation of GABA-A receptor activity", "d": ["Any process that modulates the frequency, rate or extent of GABA-A receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046430", "l": "non-phosphorylated glucose metabolic process", "d": ["The chemical reactions and pathways involving non-phosphorylated forms of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010684", "l": "tricyclic triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007367", "l": "segment polarity determination", "d": ["Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140066", "l": "peptidyl-lysine crotonylation", "d": ["The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140748", "l": "positive regulation of regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.380747715658053", "identifiers": [{"i": "GO:0001654", "l": "eye development", "d": ["The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0014743", "l": "regulation of muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033605", "l": "positive regulation of catecholamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035874", "l": "cellular response to copper ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031363", "l": "N-terminal protein amino acid deamination", "d": ["The removal of an amino group from the N-terminal amino acid residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002923", "l": "regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075045", "l": "regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.65753211953173", "identifiers": [{"i": "GO:0048511", "l": "rhythmic process", "d": ["Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002016", "l": "regulation of blood volume by renin-angiotensin", "d": ["The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000987", "l": "positive regulation of behavioral fear response", "d": ["Any process that activates or increases the frequency, rate or extent of behavioral fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010203", "l": "response to very low fluence red light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046387", "l": "deoxyribose 1,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "35.54785690096881", "identifiers": [{"i": "GO:0002164", "l": "larval development", "d": ["The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000463", "l": "positive regulation of excitatory postsynaptic potential", "d": ["Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046042", "l": "ITP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035999", "l": "tetrahydrofolate interconversion", "d": ["The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902163", "l": "negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0072089", "l": "stem cell proliferation", "d": ["The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001549", "l": "cumulus cell differentiation", "d": ["The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046418", "l": "nopaline metabolic process", "d": ["The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003026", "l": "regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback", "d": ["The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904835", "l": "dorsal root ganglion morphogenesis", "d": ["The developmental process by which a dorsal root ganglion is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090341", "l": "negative regulation of secretion of lysosomal enzymes", "d": ["Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044632", "l": "negative regulation of complement activation, lectin pathway in another organism", "d": ["Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901862", "l": "negative regulation of muscle tissue development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097062", "l": "dendritic spine maintenance", "d": ["The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002796", "l": "positive regulation of antimicrobial peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0016123", "l": "xanthophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061027", "l": "umbilical cord development", "d": ["The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901141", "l": "regulation of lignin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of lignin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042407", "l": "cristae formation", "d": ["The assembly of cristae, the inwards folds of the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000098", "l": "sulfur amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045634", "l": "regulation of melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072084", "l": "specification of distal tubule identity", "d": ["The process in which the distal tubule of the kidney nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900999", "l": "nitrobenzene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nitrobenzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061736", "l": "engulfment of target by autophagosome", "d": ["The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009649", "l": "entrainment of circadian clock", "d": ["The synchronization of a circadian rhythm to environmental time cues such as light."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902257", "l": "negative regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046722", "l": "lactic acid secretion", "d": ["The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905328", "l": "plant septum development", "d": ["The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.9246167158351", "identifiers": [{"i": "GO:0046486", "l": "glycerolipid metabolic process", "d": ["The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900445", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0052698", "l": "ergothioneine metabolic process", "d": ["The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070158", "l": "mitochondrial seryl-tRNA aminoacylation", "d": ["The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048778", "l": "regulation of erythrophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of erythrophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032902", "l": "nerve growth factor production", "d": ["The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905671", "l": "regulation of lysosome organization", "d": ["Any process that modulates the frequency, rate or extent of lysosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021517", "l": "ventral spinal cord development", "d": ["The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010117", "l": "photoprotection", "d": ["Protection mechanism used by plants and cyanobacteria under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022417", "l": "protein maturation by protein folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003290", "l": "atrial septum secundum morphogenesis", "d": ["The process in which anatomical structure of an atrial septum secundum is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002362", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098730", "l": "male germline stem cell symmetric division", "d": ["The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001037", "l": "positive regulation of tongue muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046102", "l": "inosine metabolic process", "d": ["The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032636", "l": "interleukin-7 production", "d": ["The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1904292", "l": "regulation of ERAD pathway", "d": ["Any process that modulates the frequency, rate or extent of ERAD pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021653", "l": "rhombomere 1 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0060571", "l": "morphogenesis of an epithelial fold", "d": ["The morphogenetic process in which an epithelial sheet bends along a linear axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160030", "l": "pollen intine formation", "d": ["Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990079", "l": "cartilage homeostasis", "d": ["A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019527", "l": "pentitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.483555723501368", "identifiers": [{"i": "GO:0072009", "l": "nephron epithelium development", "d": ["The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030329", "l": "prenylcysteine metabolic process", "d": ["The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010704", "l": "meiotic DNA double-strand break processing involved in meiotic gene conversion", "d": ["The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042680", "l": "compound eye cone cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110095", "l": "cellular detoxification of aldehyde", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090398", "l": "cellular senescence", "d": ["A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902334", "l": "fructose export from vacuole to cytoplasm", "d": ["The directed movement of fructose from vacuole to cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904726", "l": "regulation of replicative senescence", "d": ["Any process that modulates the frequency, rate or extent of replicative senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019517", "l": "L-threonine catabolic process to D-lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902147", "l": "regulation of response to cytokinesis checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051551", "l": "aurone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060043", "l": "regulation of cardiac muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070481", "l": "nuclear-transcribed mRNA catabolic process, non-stop decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006931", "l": "substrate-dependent cell migration, cell attachment to substrate", "d": ["The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0052093", "l": "formation of specialized structure for nutrient acquisition", "d": ["The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034490", "l": "basic amino acid transmembrane import into vacuole", "d": ["The directed movement of basic amino acids into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901461", "l": "negative regulation of response to formic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042595", "l": "behavioral response to starvation", "d": ["Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001923", "l": "B-1 B cell differentiation", "d": ["The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060163", "l": "subpallium neuron fate commitment", "d": ["The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014875", "l": "detection of muscle activity involved in regulation of muscle adaptation", "d": ["The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046437", "l": "D-amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0050923", "l": "regulation of negative chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021769", "l": "orbitofrontal cortex development", "d": ["The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0099174", "l": "regulation of presynapse organization", "d": ["Any process that modulates the physical form of a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000484", "l": "cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043303", "l": "mast cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0035304", "l": "regulation of protein dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140408", "l": "regulation of mRNA alternative polyadenylation", "d": ["Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0007135", "l": "meiosis II", "d": ["The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099041", "l": "vesicle tethering to Golgi", "d": ["The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035785", "l": "intracellular nickel ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051866", "l": "general adaptation syndrome", "d": ["General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071272", "l": "morphine metabolic process", "d": ["The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006707", "l": "cholesterol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045957", "l": "negative regulation of complement activation, alternative pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097272", "l": "ammonium homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of ammonium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904139", "l": "regulation of microglial cell migration", "d": ["Any process that modulates the frequency, rate or extent of microglial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000899", "l": "xyloglucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a xyloglucan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990153", "l": "maintenance of protein localization to heterochromatin", "d": ["A process in which a protein is maintained in a location in telomeric heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042120", "l": "alginic acid metabolic process", "d": ["The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901967", "l": "negative regulation of cellular response to iron ion starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071911", "l": "synchronous neurotransmitter secretion", "d": ["Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075046", "l": "positive regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051711", "l": "negative regulation of killing of cells of another organism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045657", "l": "positive regulation of monocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000073", "l": "regulation of cytokinesis, site selection", "d": ["Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903605", "l": "cytochrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cytochrome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018059", "l": "N-terminal peptidyl-serine deamination", "d": ["The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902253", "l": "regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042130", "l": "negative regulation of T cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010658", "l": "striated muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900077", "l": "negative regulation of cellular response to insulin stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900480", "l": "regulation of diacylglycerol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140252", "l": "regulation protein catabolic process at postsynapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903033", "l": "positive regulation of microtubule plus-end binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033380", "l": "granzyme B localization to T cell secretory granule", "d": ["Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097094", "l": "craniofacial suture morphogenesis", "d": ["The process in which any suture between cranial and/or facial bones is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034551", "l": "mitochondrial respiratory chain complex III assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060591", "l": "chondroblast differentiation", "d": ["The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009800", "l": "cinnamic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0099540", "l": "trans-synaptic signaling by neuropeptide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061934", "l": "regulation of adenine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of an adenine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061368", "l": "behavioral response to formalin induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044870", "l": "modulation by host of viral glycoprotein metabolic process", "d": ["A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019044", "l": "maintenance of viral latency", "d": ["The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018233", "l": "peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine", "d": ["The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901724", "l": "positive regulation of cell proliferation involved in kidney development", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072515", "l": "trehalose transport in response to desiccation", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019688", "l": "purine deoxyribonucleoside interconversion", "d": ["The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0039656", "l": "modulation by virus of host gene expression", "d": ["The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034050", "l": "programmed cell death induced by symbiont", "d": ["Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019610", "l": "3-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003318", "l": "cell migration to the midline involved in heart development", "d": ["The orderly movement of a cell toward the midline that contributes to the progression of the heart over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090295", "l": "nitrogen catabolite repression of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052386", "l": "cell wall thickening", "d": ["A type of cell wall modification in which the cell wall is reinforced and made thicker."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901115", "l": "erythromycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of erythromycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045830", "l": "positive regulation of isotype switching", "d": ["Any process that activates or increases the frequency, rate or extent of isotype switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046306", "l": "alkanesulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071802", "l": "negative regulation of podosome assembly", "d": ["Any process that stops, prevents or reduces the rate or extent of podosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990580", "l": "regulation of cytoplasmic translational termination", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904869", "l": "regulation of protein localization to Cajal body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000795", "l": "negative regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150153", "l": "positive regulation of interleukin-17A production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-17A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002041", "l": "intussusceptive angiogenesis", "d": ["The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043585", "l": "nose morphogenesis", "d": ["The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000712", "l": "regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019247", "l": "lactate racemization", "d": ["Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048816", "l": "ocellus morphogenesis", "d": ["The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021836", "l": "chemorepulsion involved in postnatal olfactory bulb interneuron migration", "d": ["The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072120", "l": "pronephros maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034115", "l": "negative regulation of heterotypic cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060030", "l": "dorsal convergence", "d": ["The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140547", "l": "acquisition of seed longevity", "d": ["The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0034109", "l": "homotypic cell-cell adhesion", "d": ["The attachment of a cell to a second cell of the identical type via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060525", "l": "prostate glandular acinus development", "d": ["The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120067", "l": "pyloric sphincter smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021641", "l": "trochlear nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019917", "l": "peptidyl-D-alanine racemization via peptidyl-L-serine", "d": ["The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905239", "l": "regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042786", "l": "evasion of host immune response via modulation of host antigen processing and presentation", "d": ["Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0042946", "l": "glucoside transport", "d": ["The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0046640", "l": "regulation of alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033505", "l": "floor plate morphogenesis", "d": ["The process in which the anatomical structure of the floor plate is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030919", "l": "peptidyl-serine O-acetylation", "d": ["The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033869", "l": "nucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010311", "l": "lateral root formation", "d": ["The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0034406", "l": "cell wall beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0046503", "l": "glycerolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000792", "l": "positive regulation of mesenchymal cell proliferation involved in lung development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002617", "l": "negative regulation of macrophage antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905173", "l": "eukaryotic translation initiation factor 2B complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0043300", "l": "regulation of leukocyte degranulation", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905637", "l": "regulation of mitochondrial mRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043049", "l": "otic placode formation", "d": ["The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035445", "l": "borate transmembrane transport", "d": ["The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060240", "l": "negative regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that decreases the rate, frequency or extent of the series signal transduction involved in conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0007591", "l": "molting cycle, chitin-based cuticle", "d": ["The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904077", "l": "negative regulation of estrogen biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0001704", "l": "formation of primary germ layer", "d": ["The formation of the ectoderm, mesoderm and endoderm during gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006729", "l": "tetrahydrobiopterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060522", "l": "inductive mesenchymal to epithelial cell signaling", "d": ["Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905053", "l": "positive regulation of base-excision repair", "d": ["Any process that activates or increases the frequency, rate or extent of base-excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990785", "l": "response to water-immersion restraint stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050837", "l": "peptide cross-linking via L-cysteinyl-L-selenocysteine", "d": ["The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032079", "l": "positive regulation of endodeoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904718", "l": "negative regulation of AMPA glutamate receptor clustering", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070640", "l": "vitamin D3 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018344", "l": "protein geranylgeranylation", "d": ["The covalent attachment of a geranylgeranyl group to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905811", "l": "negative regulation of excitatory synapse pruning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120245", "l": "terminal acetylenic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070275", "l": "aerobic ammonia oxidation to nitrite via pyruvic oxime", "d": ["The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071260", "l": "cellular response to mechanical stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090452", "l": "lithium ion transmembrane transport", "d": ["The directed movement of lithium ions across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900756", "l": "protein processing in phagocytic vesicle", "d": ["Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903325", "l": "positive regulation of snoRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061935", "l": "fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046036", "l": "CTP metabolic process", "d": ["The chemical reactions and pathways involving CTP, cytidine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902372", "l": "positive regulation of tRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040032", "l": "post-embryonic body morphogenesis", "d": ["The process in which the anatomical structures of the post-embryonic soma are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1902413", "l": "negative regulation of mitotic cytokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904129", "l": "positive regulation of convergent extension involved in somitogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903387", "l": "positive regulation of homophilic cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044733", "l": "envenomation resulting in modulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901715", "l": "regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021956", "l": "central nervous system interneuron axonogenesis", "d": ["Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045924", "l": "regulation of female receptivity", "d": ["Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000381", "l": "regulation of alternative mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046290", "l": "isoflavonoid phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035641", "l": "locomotory exploration behavior", "d": ["The specific movement from place to place of an organism in response to a novel environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071638", "l": "negative regulation of monocyte chemotactic protein-1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098598", "l": "learned vocalization behavior or vocal learning", "d": ["Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003019", "l": "central nervous system control of baroreceptor feedback", "d": ["The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006346", "l": "DNA methylation-dependent heterochromatin formation", "d": ["Repression of transcription by methylation of DNA, leading to the formation of heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010152", "l": "pollen maturation", "d": ["The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904305", "l": "negative regulation of gastro-intestinal system smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.527393480830405", "identifiers": [{"i": "GO:0050905", "l": "neuromuscular process", "d": ["Any process pertaining to the functions of the nervous and muscular systems of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051728", "l": "cell cycle switching, mitotic to meiotic cell cycle", "d": ["The process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019277", "l": "UDP-N-acetylgalactosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045710", "l": "negative regulation of larval salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055034", "l": "Bolwig's organ development", "d": ["The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902044", "l": "regulation of Fas signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of Fas signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072637", "l": "interleukin-32 production", "d": ["The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019679", "l": "propionate metabolic process, methylcitrate cycle", "d": ["The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043107", "l": "type IV pilus-dependent motility", "d": ["Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905448", "l": "positive regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015890", "l": "nicotinamide mononucleotide transport", "d": ["The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903826", "l": "L-arginine transmembrane transport", "d": ["The directed movement of L-arginine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903634", "l": "negative regulation of leucine-tRNA ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905936", "l": "regulation of germ cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034182", "l": "regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900272", "l": "negative regulation of long-term synaptic potentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905010", "l": "positive regulation of L-lysine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-lysine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042183", "l": "formate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030949", "l": "positive regulation of vascular endothelial growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002303", "l": "gamma-delta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090347", "l": "regulation of cellular organohalogen metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.994560329557565", "identifiers": [{"i": "GO:0002504", "l": "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070633", "l": "transepithelial transport", "d": ["The directed movement of a substance from one side of an epithelium to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046897", "l": "N-terminal peptidyl-tyrosine methylation", "d": ["The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002090", "l": "regulation of receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901150", "l": "vistamycin metabolic process", "d": ["The chemical reactions and pathways involving vistamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034499", "l": "late endosome to Golgi transport", "d": ["The directed movement of substances from late endosomes to the Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901924", "l": "positive regulation of sclerotium development", "d": ["Any process that activates or increases the frequency, rate or extent of sclerotium development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018156", "l": "peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060683", "l": "regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling", "d": ["Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061199", "l": "striated muscle contraction involved in embryonic body morphogenesis", "d": ["The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034461", "l": "uropod retraction", "d": ["The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071982", "l": "maintenance of diapause", "d": ["The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071918", "l": "urea transmembrane transport", "d": ["The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034105", "l": "positive regulation of tissue remodeling", "d": ["Any process that activates or increases the frequency, rate, or extent of tissue remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902289", "l": "negative regulation of defense response to oomycetes", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990830", "l": "cellular response to leukemia inhibitory factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.81386474005091", "identifiers": [{"i": "GO:0030154", "l": "cell differentiation", "d": ["The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038019", "l": "Wnt receptor recycling", "d": ["The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042482", "l": "positive regulation of odontogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034354", "l": "'de novo' NAD biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006436", "l": "tryptophanyl-tRNA aminoacylation", "d": ["The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071486", "l": "cellular response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080022", "l": "primary root development", "d": ["The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018971", "l": "anaerobic toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014737", "l": "positive regulation of muscle atrophy", "d": ["Any process that activates or increases the frequency, rate or extent of muscle atrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071250", "l": "cellular response to nitrite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014911", "l": "positive regulation of smooth muscle cell migration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0050678", "l": "regulation of epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034607", "l": "turning behavior involved in mating", "d": ["The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.188159350298456", "identifiers": [{"i": "GO:0065003", "l": "protein-containing complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046130", "l": "purine ribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045105", "l": "intermediate filament polymerization or depolymerization", "d": ["Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000489", "l": "maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010398", "l": "xylogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904424", "l": "regulation of GTP binding", "d": ["Any process that modulates the frequency, rate or extent of GTP binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0070972", "l": "protein localization to endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0006677", "l": "glycosylceramide metabolic process", "d": ["The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150036", "l": "regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0002244", "l": "hematopoietic progenitor cell differentiation", "d": ["The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900739", "l": "regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902735", "l": "negative regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040026", "l": "positive regulation of vulval development", "d": ["Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033477", "l": "S-methylmethionine metabolic process", "d": ["The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010863", "l": "positive regulation of phospholipase C activity", "d": ["Any process that increases the rate of phospholipase C activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006266", "l": "DNA ligation", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009939", "l": "positive regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071672", "l": "negative regulation of smooth muscle cell chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904397", "l": "negative regulation of neuromuscular junction development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051625", "l": "epinephrine uptake", "d": ["The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000263", "l": "regulation of blood coagulation, extrinsic pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075297", "l": "negative regulation of ascospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003164", "l": "His-Purkinje system development", "d": ["The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010401", "l": "pectic galactan metabolic process", "d": ["The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.50754995026157", "identifiers": [{"i": "GO:0048285", "l": "organelle fission", "d": ["The creation of two or more organelles by division of one organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006847", "l": "plasma membrane acetate transport", "d": ["The directed movement of acetate across a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061109", "l": "dense core granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001091", "l": "nigerotriose transport", "d": ["The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0005991", "l": "trehalose metabolic process", "d": ["The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.999360615610847", "identifiers": [{"i": "GO:0051726", "l": "regulation of cell cycle", "d": ["Any process that modulates the rate or extent of progression through the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036269", "l": "swimming behavior", "d": ["The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035680", "l": "posterior lateral line neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009302", "l": "sno(s)RNA transcription", "d": ["The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032827", "l": "negative regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905776", "l": "positive regulation of DNA helicase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036529", "l": "protein deglycation, glyoxal removal", "d": ["The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060269", "l": "centripetally migrating follicle cell migration", "d": ["The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071252", "l": "cellular response to sulfur dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140735", "l": "lovastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000462", "l": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001212", "l": "regulation of vasculogenesis", "d": ["Any process that modulates the frequency, rate or extent of vasculogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035261", "l": "external genitalia morphogenesis", "d": ["The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001114", "l": "positive regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160038", "l": "somatic sensory system development", "d": ["The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902057", "l": "(25S)-Delta(4)-dafachronate metabolic process", "d": ["The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060992", "l": "response to fungicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000328", "l": "regulation of T-helper 17 cell lineage commitment", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039701", "l": "microtubule-dependent intracellular transport of viral material towards cell periphery", "d": ["The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010867", "l": "positive regulation of triglyceride biosynthetic process", "d": ["Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033495", "l": "ferulate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019506", "l": "phenylmercury acetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014717", "l": "regulation of satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042905", "l": "9-cis-retinoic acid metabolic process", "d": ["The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901288", "l": "iron-sulfur-molybdenum cofactor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010441", "l": "guard cell development", "d": ["The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021969", "l": "corticospinal neuron axon guidance through the cerebral peduncle", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010617", "l": "circadian regulation of calcium ion oscillation", "d": ["Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031156", "l": "regulation of sorocarp development", "d": ["Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901451", "l": "regulation of response to benzene", "d": ["Any process that modulates the frequency, rate or extent of response to benzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070346", "l": "positive regulation of fat cell proliferation", "d": ["Any process that activates or increases the rate or extent of fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001984", "l": "artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043654", "l": "recognition of apoptotic cell", "d": ["The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071332", "l": "cellular response to fructose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061480", "l": "response to asparaginase", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021676", "l": "rhombomere 8 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900661", "l": "regulation of emericellamide A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000255", "l": "allantoin metabolic process", "d": ["The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990217", "l": "suppression by symbiont of host phytoalexin production", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006526", "l": "arginine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035640", "l": "exploration behavior", "d": ["The specific behavior of an organism in response to a novel environment or stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001662", "l": "behavioral fear response", "d": ["An acute behavioral change resulting from a perceived external threat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071642", "l": "positive regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0002686", "l": "negative regulation of leukocyte migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072022", "l": "descending thin limb development", "d": ["The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900099", "l": "negative regulation of plasma cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051549", "l": "positive regulation of keratinocyte migration", "d": ["Any process that activates or increases the frequency, rate or extent of keratinocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021708", "l": "Lugaro cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0060761", "l": "negative regulation of response to cytokine stimulus", "d": ["Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140317", "l": "export across cell outer membrane", "d": ["The directed movement of a substance across the outer membrane in cells with two membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015952", "l": "purine deoxyribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006021", "l": "inositol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0036265", "l": "RNA (guanine-N7)-methylation", "d": ["The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0043545", "l": "molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001737", "l": "establishment of imaginal disc-derived wing hair orientation", "d": ["Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018270", "l": "GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051469", "l": "vesicle fusion with vacuole", "d": ["The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990182", "l": "exosomal secretion", "d": ["The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070086", "l": "ubiquitin-dependent endocytosis", "d": ["Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902519", "l": "response to docetaxel trihydrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0071706", "l": "tumor necrosis factor superfamily cytokine production", "d": ["The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140123", "l": "negative regulation of Lewy body formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902558", "l": "5'-adenylyl sulfate transmembrane transport", "d": ["The process in which 5'-adenylyl sulfate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035852", "l": "horizontal cell localization", "d": ["Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035180", "l": "larval wandering behavior", "d": ["The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070189", "l": "kynurenine metabolic process", "d": ["The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002598", "l": "regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904943", "l": "negative regulation of cardiac ventricle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0100010", "l": "positive regulation of fever generation by prostaglandin biosynthetic process", "d": ["Any prostaglandin biosynthetic process process that positively_regulates fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030513", "l": "positive regulation of BMP signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901772", "l": "lincomycin metabolic process", "d": ["The chemical reactions and pathways involving lincomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007537", "l": "inactivation of recombination (HML)", "d": ["The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905174", "l": "regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0006476", "l": "protein deacetylation", "d": ["The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905005", "l": "regulation of epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048147", "l": "negative regulation of fibroblast proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051633", "l": "positive regulation of acetylcholine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0001823", "l": "mesonephros development", "d": ["The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061766", "l": "positive regulation of lung blood pressure", "d": ["The process that increases the force with which blood travels through the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050973", "l": "detection of mechanical stimulus involved in equilibrioception", "d": ["The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045984", "l": "negative regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000155", "l": "positive regulation of cilium-dependent cell motility", "d": ["Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010591", "l": "regulation of lamellipodium assembly", "d": ["Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042590", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0071963", "l": "establishment or maintenance of cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006222", "l": "UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030997", "l": "regulation of centriole-centriole cohesion", "d": ["Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070495", "l": "negative regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001116", "l": "protein-DNA-RNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0050951", "l": "sensory perception of temperature stimulus", "d": ["The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046062", "l": "dCDP metabolic process", "d": ["The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007615", "l": "anesthesia-resistant memory", "d": ["The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048314", "l": "embryo sac morphogenesis", "d": ["The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:2000243", "l": "positive regulation of reproductive process", "d": ["Any process that activates or increases the frequency, rate or extent of reproductive process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900130", "l": "regulation of lipid binding", "d": ["Any process that modulates the frequency, rate or extent of lipid binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002235", "l": "detection of unfolded protein", "d": ["The series of events in which an unfolded protein stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006378", "l": "mRNA polyadenylation", "d": ["The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060463", "l": "lung lobe morphogenesis", "d": ["The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010783", "l": "proboscis morphogenesis, eye-antennal disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060913", "l": "cardiac cell fate determination", "d": ["The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043982", "l": "histone H4-K8 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.487843165973111", "identifiers": [{"i": "GO:0009416", "l": "response to light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033688", "l": "regulation of osteoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of osteoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032012", "l": "regulation of ARF protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of ARF protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044660", "l": "viral release via pore formation in host cell membrane", "d": ["The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905757", "l": "negative regulation of primary cell septum biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034498", "l": "early endosome to Golgi transport", "d": ["The directed movement of substances from early endosomes to the Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010202", "l": "response to low fluence red light stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902162", "l": "regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002320", "l": "lymphoid progenitor cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. 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It does not include processes where the neuroblast turns into a glial cell or a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000426", "l": "negative regulation of apoptotic cell clearance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0042723", "l": "thiamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905817", "l": "positive regulation of dorsal/ventral axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900878", "l": "(Z)-nonadeca-1,14-diene metabolic process", "d": ["The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:2000197", "l": "regulation of ribonucleoprotein complex localization", "d": ["Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009997", "l": "negative regulation of cardioblast cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016103", "l": "diterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015670", "l": "carbon dioxide transport", "d": ["The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061865", "l": "polarized secretion of basement membrane proteins in epithelium", "d": ["The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0036161", "l": "calcitonin secretion", "d": ["The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032462", "l": "regulation of protein homooligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein homooligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043267", "l": "negative regulation of potassium ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071072", "l": "negative regulation of phospholipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072387", "l": "flavin adenine dinucleotide metabolic process", "d": ["The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120312", "l": "ciliary basal body segregation", "d": ["The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034192", "l": "D-galactonate metabolic process", "d": ["The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032334", "l": "inhibin secretion", "d": ["The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098755", "l": "maintenance of seed dormancy by absisic acid", "d": ["The process by which seed dormancy is maintained by the presence of absisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.702982456578013", "identifiers": [{"i": "GO:0030163", "l": "protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1900368", "l": "regulation of post-transcriptional gene silencing by regulatory ncRNA", "d": ["Any process that modulates the frequency, rate or extent of post-transcriptional gene silencing by a non-coding RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000367", "l": "regulation of acrosomal vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070797", "l": "negative regulation of cleistothecium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180002", "l": "renal zinc excretion", "d": ["The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903116", "l": "positive regulation of actin filament-based movement", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament-based movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062094", "l": "stomach development", "d": ["The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. 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It is a member of the B complex of vitamins and occurs widely in living organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035138", "l": "pectoral fin morphogenesis", "d": ["The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030645", "l": "glucose catabolic process to butyrate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006170", "l": "dAMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014839", "l": "myoblast migration involved in skeletal muscle regeneration", "d": ["The process in which a myoblast migrates along an entire fiber to the site of injury. 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Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036365", "l": "transforming growth factor beta2 activation", "d": ["The release of transforming growth factor beta 2 (TGF-beta2) from its latent state."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052804", "l": "nitroimidazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035894", "l": "induction of platelet aggregation in another organism", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902062", "l": "betaine aldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of betaine aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010346", "l": "shoot axis formation", "d": ["The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901523", "l": "icosanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of icosanoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:1901071", "l": "glucosamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900110", "l": "negative regulation of histone H3-K9 dimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046180", "l": "ketogluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042846", "l": "glycol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002719", "l": "negative regulation of cytokine production involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120292", "l": "positive regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. 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Proteins involved in homologous recombination are required for replication restart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002610", "l": "regulation of plasmacytoid dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.128670511712357", "identifiers": [{"i": "GO:0050974", "l": "detection of mechanical stimulus involved in sensory perception", "d": ["The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072438", "l": "response to DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900727", "l": "osmoregulated periplasmic glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120223", "l": "larynx morphogenesis", "d": ["The process in which the larynx is generated and organized. 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"biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000428", "l": "regulation of neutrophil aggregation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046963", "l": "3'-phosphoadenosine 5'-phosphosulfate transport", "d": ["The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904231", "l": "positive regulation of succinate dehydrogenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035047", "l": "centrosomal and pronuclear rotation", "d": ["The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000590", "l": "negative regulation of metanephric mesenchymal cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905531", "l": "positive regulation of uracil import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034195", "l": "L-galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006574", "l": "valine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002674", "l": "negative regulation of acute inflammatory response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032008", "l": "positive regulation of TOR signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TOR signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.546041402708859", "identifiers": [{"i": "GO:0031327", "l": "negative regulation of cellular biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070299", "l": "positive regulation of phosphorelay signal transduction system", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0048332", "l": "mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the mesoderm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072262", "l": "metanephric glomerular mesangial cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019331", "l": "anaerobic respiration, using ammonium as electron donor", "d": ["The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902607", "l": "negative regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051654", "l": "establishment of mitochondrion localization", "d": ["The directed movement of the mitochondrion to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019614", "l": "catechol-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902308", "l": "regulation of peptidyl-serine dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046319", "l": "positive regulation of glucosylceramide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904069", "l": "ascaroside metabolic process", "d": ["The chemical reactions and pathways involving ascaroside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016488", "l": "farnesol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0042987", "l": "amyloid precursor protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070707", "l": "RNA dinucleotide insertion", "d": ["The modification of an RNA molecule by insertion of a dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030322", "l": "stabilization of membrane potential", "d": ["The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001209", "l": "positive regulation of transcription elongation by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006115", "l": "ethanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006101", "l": "citrate metabolic process", "d": ["The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051642", "l": "centrosome localization", "d": ["Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006893", "l": "Golgi to plasma membrane transport", "d": ["The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045013", "l": "carbon catabolite repression of transcription", "d": ["A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021986", "l": "habenula development", "d": ["The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901449", "l": "negative regulation of response to butan-1-ol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006754", "l": "ATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042621", "l": "poly(3-hydroxyalkanoate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048399", "l": "regulation of intermediate mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:1901376", "l": "organic heteropentacyclic compound metabolic process", "d": ["The chemical reactions and pathways involving organic heteropentacyclic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0043446", "l": "cellular alkane metabolic process", "d": ["The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030212", "l": "hyaluronan metabolic process", "d": ["The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0032620", "l": "interleukin-17 production", "d": ["The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060083", "l": "smooth muscle contraction involved in micturition", "d": ["The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045886", "l": "negative regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050937", "l": "regulation of iridophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of iridophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900802", "l": "cspyrone B1 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cspyrone B1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009652", "l": "thigmotropism", "d": ["The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904043", "l": "positive regulation of cystathionine beta-synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000409", "l": "positive regulation of T cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060649", "l": "mammary gland bud elongation", "d": ["The process in which the mammary gland bud grows along its axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901178", "l": "spheroidene metabolic process", "d": ["The chemical reactions and pathways involving spheroidene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033169", "l": "histone H3-K9 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902348", "l": "cellular response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.102751562300085", "identifiers": [{"i": "GO:0045321", "l": "leukocyte activation", "d": ["A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:1900047", "l": "negative regulation of hemostasis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904772", "l": "response to tetrachloromethane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903345", "l": "negative regulation of protein polyglycylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090070", "l": "positive regulation of ribosome biogenesis", "d": ["Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061193", "l": "taste bud development", "d": ["The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030311", "l": "poly-N-acetyllactosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904429", "l": "regulation of t-circle formation", "d": ["Any process that modulates the frequency, rate or extent of t-circle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021941", "l": "negative regulation of cerebellar granule cell precursor proliferation", "d": ["The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072740", "l": "cellular response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903314", "l": "regulation of nitrogen cycle metabolic process", "d": ["Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072283", "l": "metanephric renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052163", "l": "symbiont defense to host-produced nitric oxide", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990966", "l": "ATP generation from poly-ADP-D-ribose", "d": ["The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0018282", "l": "metal incorporation into metallo-sulfur cluster", "d": ["The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061959", "l": "response to (R)-carnitine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061211", "l": "mesonephric collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019454", "l": "L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase", "d": ["The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048712", "l": "negative regulation of astrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000288", "l": "positive regulation of myoblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072190", "l": "ureter urothelium development", "d": ["The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.608741564042447", "identifiers": [{"i": "GO:0002440", "l": "production of molecular mediator of immune response", "d": ["The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2001006", "l": "regulation of cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000164", "l": "negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044623", "l": "positive regulation of cell migration in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of cell migration in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034438", "l": "lipoprotein amino acid oxidation", "d": ["The modification of a lipoprotein by oxidation of one or more amino acids in the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0051608", "l": "histamine transport", "d": ["The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070173", "l": "regulation of enamel mineralization", "d": ["Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0075015", "l": "formation of infection structure", "d": ["The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051657", "l": "maintenance of organelle location", "d": ["Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045327", "l": "protein-DNA covalent cross-linking via peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009739", "l": "response to gibberellin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061792", "l": "secretory granule maturation", "d": ["Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071562", "l": "nucleus-vacuole junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0007637", "l": "proboscis extension reflex", "d": ["The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0051304", "l": "chromosome separation", "d": ["The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0002516", "l": "B cell deletion", "d": ["The apoptotic death of B cells which is part of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902865", "l": "positive regulation of embryonic camera-type eye development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098511", "l": "sensory perception of low humidity", "d": ["The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0030149", "l": "sphingolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048297", "l": "negative regulation of isotype switching to IgA isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002317", "l": "plasma cell differentiation", "d": ["The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090291", "l": "negative regulation of osteoclast proliferation", "d": ["Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905583", "l": "cellular response to mannose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.007347202863528", "identifiers": [{"i": "GO:0072698", "l": "protein localization to microtubule cytoskeleton", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0048366", "l": "leaf development", "d": ["The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006550", "l": "isoleucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905073", "l": "regulation of tight junction disassembly", "d": ["Any process that modulates the frequency, rate or extent of tight junction disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062230", "l": "negative regulation of larval somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of larval somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002414", "l": "immunoglobulin transcytosis in epithelial cells", "d": ["The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046282", "l": "cinnamic acid ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.16494433675436", "identifiers": [{"i": "GO:0061527", "l": "dopamine secretion, neurotransmission", "d": ["The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030912", "l": "response to deep water", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0030707", "l": "follicle cell of egg chamber development", "d": ["The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030860", "l": "regulation of polarized epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072596", "l": "establishment of protein localization to chloroplast", "d": ["The directed movement of a protein to a specific location in a chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903260", "l": "protein localization to mating projection tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a mating projection tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072201", "l": "negative regulation of mesenchymal cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905013", "l": "negative regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099159", "l": "regulation of modification of postsynaptic structure", "d": ["Any process that modulates the frequency, rate or extent of modification of postsynaptic structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002623", "l": "negative regulation of B cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036164", "l": "cell-abiotic substrate adhesion", "d": ["The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0045763", "l": "negative regulation of cellular amino acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903471", "l": "regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060765", "l": "regulation of androgen receptor signaling pathway", "d": ["Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007419", "l": "ventral cord development", "d": ["The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072123", "l": "intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904503", "l": "negative regulation of lipophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903920", "l": "positive regulation of actin filament severing", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament severing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071449", "l": "cellular response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0043605", "l": "amide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075512", "l": "clathrin-dependent endocytosis of virus by host cell", "d": ["Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018095", "l": "protein polyglutamylation", "d": ["The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0015671", "l": "oxygen transport", "d": ["The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.401997675337611", "identifiers": [{"i": "GO:0009967", "l": "positive regulation of signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002605", "l": "negative regulation of dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901426", "l": "response to furfural", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990067", "l": "intrachromosomal DNA recombination", "d": ["The process of DNA recombination occurring within a single chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901039", "l": "regulation of peptide antigen transport", "d": ["Any process that modulates the frequency, rate or extent of peptide antigen transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1903666", "l": "positive regulation of asexual reproduction", "d": ["Any process that activates or increases the frequency, rate or extent of asexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070951", "l": "regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900882", "l": "17-methylnonadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving 17-methylnonadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0036363", "l": "transforming growth factor beta activation", "d": ["The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0038017", "l": "Wnt receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003313", "l": "heart rudiment development", "d": ["The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904814", "l": "regulation of protein localization to chromosome, telomeric region", "d": ["Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061728", "l": "GDP-mannose biosynthetic process from mannose", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140059", "l": "dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905765", "l": "negative regulation of protection from non-homologous end joining at telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904353", "l": "regulation of telomere capping", "d": ["Any process that modulates the frequency, rate or extent of telomere capping."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010392", "l": "galactoglucomannan metabolic process", "d": ["The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051470", "l": "ectoine transport", "d": ["The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008346", "l": "larval walking behavior", "d": ["The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0031279", "l": "regulation of cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034475", "l": "U4 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U4 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106021", "l": "negative regulation of vesicle docking", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048575", "l": "short-day photoperiodism, flowering", "d": ["A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072302", "l": "negative regulation of metanephric glomerular mesangial cell proliferation", "d": ["Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.125277166295454", "identifiers": [{"i": "GO:0032787", "l": "monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903727", "l": "positive regulation of phospholipid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150073", "l": "regulation of protein-glutamine gamma-glutamyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006672", "l": "ceramide metabolic process", "d": ["The chemical reactions and pathways involving ceramides, any N-acylated sphingoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043464", "l": "malolactic fermentation", "d": ["The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036227", "l": "mitotic G2 cell cycle arrest in response to glucose starvation", "d": ["The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901267", "l": "cephalosporin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cephalosporin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021714", "l": "inferior olivary nucleus morphogenesis", "d": ["The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033382", "l": "maintenance of granzyme B location in T cell secretory granule", "d": ["A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015987", "l": "GTP synthesis coupled proton transport", "d": ["The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010206", "l": "photosystem II repair", "d": ["Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090628", "l": "plant epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000074", "l": "regulation of type B pancreatic cell development", "d": ["Any process that modulates the frequency, rate or extent of pancreatic B cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.423950427221243", "identifiers": [{"i": "GO:2000147", "l": "positive regulation of cell motility", "d": ["Any process that activates or increases the frequency, rate or extent of cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0071894", "l": "histone H2B conserved C-terminal lysine ubiquitination", "d": ["A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006880", "l": "intracellular sequestering of iron ion", "d": ["The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000646", "l": "positive regulation of receptor catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of receptor catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000010", "l": "positive regulation of protein localization to cell surface", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010811", "l": "positive regulation of cell-substrate adhesion", "d": ["Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901940", "l": "(-)-exo-alpha-bergamotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021650", "l": "vestibulocochlear nerve formation", "d": ["The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048459", "l": "floral whorl structural organization", "d": ["The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019426", "l": "bisulfite reduction", "d": ["The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1901900", "l": "regulation of protein localization to cell division site", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell division site."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051255", "l": "spindle midzone assembly", "d": ["The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904774", "l": "negative regulation of ubiquinone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904230", "l": "negative regulation of succinate dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003357", "l": "noradrenergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901307", "l": "positive regulation of spermidine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072233", "l": "metanephric thick ascending limb development", "d": ["The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0120275", "l": "cerebral blood circulation", "d": ["The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030033", "l": "microvillus assembly", "d": ["Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090516", "l": "L-serine transmembrane import into vacuole", "d": ["The directed movement of L-serine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0033045", "l": "regulation of sister chromatid segregation", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035331", "l": "negative regulation of hippo signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903571", "l": "negative regulation of protein kinase D signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0060206", "l": "estrous cycle phase", "d": ["The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903811", "l": "L-asparagine import across plasma membrane", "d": ["The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046055", "l": "dGMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0075111", "l": "symbiont-mediated suppression of host receptor-mediated signal transduction", "d": ["A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1901401", "l": "regulation of tetrapyrrole metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045342", "l": "MHC class II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0001832", "l": "blastocyst growth", "d": ["An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:1903008", "l": "organelle disassembly", "d": ["The disaggregation of an organelle into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019295", "l": "coenzyme M biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0030073", "l": "insulin secretion", "d": ["The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.648342010697611", "identifiers": [{"i": "GO:0002443", "l": "leukocyte mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a leukocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072188", "l": "metanephric cap specification", "d": ["The process in which the metanephric cap acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075218", "l": "zoospore encystment on host", "d": ["The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075227", "l": "regulation of encysted zoospore germination", "d": ["Any process that modulates the frequency, rate or extent of an encysted zoospore germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902595", "l": "regulation of DNA replication origin binding", "d": ["Any process that modulates the frequency, rate or extent of DNA replication origin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001226", "l": "negative regulation of chloride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901119", "l": "tobramycin metabolic process", "d": ["The chemical reactions and pathways involving tobramycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901173", "l": "phytoene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytoene."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.271170648665588", "identifiers": [{"i": "GO:0022613", "l": "ribonucleoprotein complex biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0022602", "l": "ovulation cycle process", "d": ["A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051950", "l": "positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099051", "l": "vesicle scission involved in endocytosis", "d": ["The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000801", "l": "negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0062036", "l": "sensory perception of hot stimulus", "d": ["The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071356", "l": "cellular response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.481265292451688", "identifiers": [{"i": "GO:0018958", "l": "phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903511", "l": "orotic acid metabolic process", "d": ["The chemical reactions and pathways involving orotic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071520", "l": "actomyosin contractile ring assembly actin filament bundle convergence", "d": ["A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1903019", "l": "negative regulation of glycoprotein metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090073", "l": "positive regulation of protein homodimerization activity", "d": ["Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039587", "l": "suppression by virus of host tetherin activity", "d": ["Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009226", "l": "nucleotide-sugar biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.166816093753788", "identifiers": [{"i": "GO:0009792", "l": "embryo development ending in birth or egg hatching", "d": ["The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903455", "l": "negative regulation of androst-4-ene-3,17-dione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000062", "l": "negative regulation of ureter smooth muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051562", "l": "negative regulation of mitochondrial calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072660", "l": "maintenance of protein location in plasma membrane", "d": ["Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014901", "l": "satellite cell activation involved in skeletal muscle regeneration", "d": ["The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014832", "l": "urinary bladder smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097207", "l": "bud dormancy process", "d": ["A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002531", "l": "regulation of heart contraction involved in acute-phase response", "d": ["Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051826", "l": "negative regulation of synapse structural plasticity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042573", "l": "retinoic acid metabolic process", "d": ["The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034383", "l": "low-density lipoprotein particle clearance", "d": ["The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071529", "l": "cementum mineralization", "d": ["The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018256", "l": "protein formylation", "d": ["The addition of a formyl group to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035341", "l": "regulation of inosine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904893", "l": "negative regulation of receptor signaling pathway via STAT", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904751", "l": "positive regulation of protein localization to nucleolus", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034427", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'", "d": ["The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007412", "l": "axon target recognition", "d": ["The process in which an axon recognizes and binds to a set of cells with which it may form stable connections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002230", "l": "positive regulation of defense response to virus by host", "d": ["Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018302", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061716", "l": "miRNA export from nucleus", "d": ["The directed movement of a processed miRNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0006163", "l": "purine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034021", "l": "response to silicon dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904198", "l": "negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048313", "l": "Golgi inheritance", "d": ["The partitioning of Golgi apparatus between daughter cells at cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033073", "l": "pinene metabolic process", "d": ["The chemical reactions and pathways involving the monoterpenoid pinene; 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It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904904", "l": "regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0003389", "l": "retrograde extension", "d": ["The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0051156", "l": "glucose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0009309", "l": "amine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051455", "l": "spindle attachment to meiosis I kinetochore", "d": ["The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034030", "l": "ribonucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990387", "l": "isogloboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032932", "l": "negative regulation of astral microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033358", "l": "UDP-L-arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097752", "l": "regulation of DNA stability", "d": ["Any process that modulates the stability of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903267", "l": "negative regulation of ornithine catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052781", "l": "chitobiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0018945", "l": "organosilicon metabolic process", "d": ["The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0043255", "l": "regulation of carbohydrate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080136", "l": "priming of cellular response to stress", "d": ["The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0007525", "l": "somatic muscle development", "d": ["The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060812", "l": "orthodenticle mRNA localization", "d": ["Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060877", "l": "regionalization involved in semicircular canal formation", "d": ["The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014847", "l": "proximal stomach smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902260", "l": "negative regulation of delayed rectifier potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061054", "l": "dermatome development", "d": ["The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.249294244241668", "identifiers": [{"i": "GO:0051179", "l": "localization", "d": ["Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043607", "l": "formamide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060081", "l": "membrane hyperpolarization", "d": ["The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0002832", "l": "negative regulation of response to biotic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0071229", "l": "cellular response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990963", "l": "establishment of blood-retinal barrier", "d": ["Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032949", "l": "regulation of alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.283525407030115", "identifiers": [{"i": "GO:0008152", "l": "metabolic process", "d": ["The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.212364561755692", "identifiers": [{"i": "GO:0072175", "l": "epithelial tube formation", "d": ["The developmental process pertaining to the initial formation of an epithelial tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015738", "l": "glucuronate transmembrane transport", "d": ["The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0018366", "l": "chiral amino acid racemization", "d": ["The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036460", "l": "cellular response to cell envelope stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044787", "l": "bacterial-type DNA replication", "d": ["The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018908", "l": "organosulfide cycle", "d": ["A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061155", "l": "pulmonary artery endothelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0097186", "l": "amelogenesis", "d": ["The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0006942", "l": "regulation of striated muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of striated muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901056", "l": "trimethylenediamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trimethylenediamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048093", "l": "positive regulation of male pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009097", "l": "isoleucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048668", "l": "collateral sprouting", "d": ["The process in which outgrowths develop from the shafts of existing axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0106027", "l": "neuron projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044180", "l": "filamentous growth of a unicellular organism", "d": ["The process in which a unicellular organism grows in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010208", "l": "pollen wall assembly", "d": ["The formation of reticulate pollen wall pattern consisting of two layers, exine and intine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021670", "l": "lateral ventricle development", "d": ["The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0010644", "l": "cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0072014", "l": "proximal tubule development", "d": ["The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019292", "l": "tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009437", "l": "carnitine metabolic process", "d": ["The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0031649", "l": "heat generation", "d": ["Any homeostatic process in which an organism produces heat, thereby raising its internal temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903094", "l": "negative regulation of protein K48-linked deubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006640", "l": "monoacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1901890", "l": "positive regulation of cell junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cell junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1900732", "l": "regulation of polyketide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of polyketide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071939", "l": "vitamin A import into cell", "d": ["The directed movement of vitamin A from outside of a cell, across the plasma membrane and into the cytosol. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071104", "l": "response to interleukin-9", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001237", "l": "negative regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045740", "l": "positive regulation of DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048091", "l": "positive regulation of female pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021562", "l": "vestibulocochlear nerve development", "d": ["The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071039", "l": "nuclear polyadenylation-dependent CUT catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905215", "l": "negative regulation of RNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048377", "l": "lateral mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018217", "l": "peptidyl-aspartic acid phosphorylation", "d": ["The phosphorylation of peptidyl-aspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.435109751520386", "identifiers": [{"i": "GO:0051276", "l": "chromosome organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061796", "l": "membrane addition at site of mitotic cytokinesis", "d": ["A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033372", "l": "establishment of protease localization to mast cell secretory granule", "d": ["The directed movement of a protease to a location within a secretory granule in a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097374", "l": "sensory neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901058", "l": "p-hydroxyphenyl lignin metabolic process", "d": ["The chemical reactions and pathways involving p-hydroxyphenyl lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061872", "l": "hepatic stellate cell contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002681", "l": "somatic recombination of T cell receptor gene segments", "d": ["The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900624", "l": "negative regulation of monocyte aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905115", "l": "regulation of lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071940", "l": "fungal-type cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080189", "l": "primary growth", "d": ["Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990090", "l": "cellular response to nerve growth factor stimulus", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046411", "l": "2-keto-3-deoxygluconate transmembrane transport", "d": ["The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031426", "l": "polycistronic mRNA processing", "d": ["The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044573", "l": "nitrogenase P cluster assembly", "d": ["The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902947", "l": "regulation of tau-protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of tau-protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044345", "l": "stromal-epithelial cell signaling involved in prostate gland development", "d": ["The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070485", "l": "dehydro-D-arabinono-1,4-lactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098507", "l": "polynucleotide 5' dephosphorylation", "d": ["The process of removing one or more phosphate groups from the 5' end of a polynucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150201", "l": "positive regulation of transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034552", "l": "respiratory chain complex II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902299", "l": "pre-replicative complex assembly involved in cell cycle DNA replication", "d": ["Any pre-replicative complex assembly that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903642", "l": "regulation of recombination hotspot binding", "d": ["Any process that modulates the frequency, rate or extent of recombination hotspot binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070178", "l": "D-serine metabolic process", "d": ["The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061096", "l": "negative regulation of turning behavior involved in mating", "d": ["Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900881", "l": "18-methylnonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090259", "l": "regulation of retinal ganglion cell axon guidance", "d": ["Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032401", "l": "establishment of melanosome localization", "d": ["The directed movement of a melanosome to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070785", "l": "negative regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070932", "l": "histone H3 deacetylation", "d": ["The modification of histone H3 by the removal of one or more acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043442", "l": "acetoacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120143", "l": "negative regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001951", "l": "intestinal D-glucose absorption", "d": ["Uptake of D-glucose into the blood by absorption from the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990532", "l": "stress response to nickel ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099586", "l": "release of sequestered calcium ion into postsynaptic cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035106", "l": "operant conditioning", "d": ["Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048843", "l": "negative regulation of axon extension involved in axon guidance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001113", "l": "transcription open complex formation at RNA polymerase II promoter", "d": ["Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045668", "l": "negative regulation of osteoblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045584", "l": "negative regulation of cytotoxic T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048007", "l": "antigen processing and presentation, exogenous lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060362", "l": "flight involved in flight behavior", "d": ["Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044475", "l": "envenomation resulting in negative regulation of high voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046178", "l": "D-gluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045963", "l": "negative regulation of dopamine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030712", "l": "negative regulation of border follicle cell delamination", "d": ["Any process that decreases the frequency, rate or extent of border cell delamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060540", "l": "diaphragm morphogenesis", "d": ["The process in which the anatomical structures of the diaphragm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901328", "l": "response to cytochalasin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018412", "l": "protein O-glucuronidation", "d": ["The modification of a protein by glucuronidation on an amino acid oxygen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905493", "l": "regulation of G-quadruplex DNA binding", "d": ["Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904032", "l": "regulation of t-SNARE clustering", "d": ["Any process that modulates the frequency, rate or extent of t-SNARE clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070108", "l": "negative regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099190", "l": "postsynaptic spectrin-associated cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0098977", "l": "inhibitory chemical synaptic transmission", "d": ["Synaptic transmission that results in an inhibitory postsynaptic potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070303", "l": "negative regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080129", "l": "proteasome core complex assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006708", "l": "ecdysone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019681", "l": "acetyl-CoA assimilation pathway", "d": ["The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009677", "l": "double fertilization forming two zygotes", "d": ["Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002576", "l": "platelet degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033509", "l": "glutamate catabolic process to propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000019", "l": "regulation of mitotic recombination", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018868", "l": "2-aminobenzenesulfonate metabolic process", "d": ["The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140569", "l": "extraction of mislocalized protein from ER membrane", "d": ["The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.057554535231027", "identifiers": [{"i": "GO:0006955", "l": "immune response", "d": ["Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0005994", "l": "melibiose metabolic process", "d": ["The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0045185", "l": "maintenance of protein location", "d": ["Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050494", "l": "GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009685", "l": "gibberellin metabolic process", "d": ["The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098757", "l": "cellular response to interleukin-21", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0033627", "l": "cell adhesion mediated by integrin", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048379", "l": "positive regulation of lateral mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099607", "l": "lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032628", "l": "interleukin-24 production", "d": ["The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007058", "l": "spindle assembly involved in female meiosis II", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070141", "l": "response to UV-A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070792", "l": "Hulle cell development", "d": ["The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061585", "l": "orexin secretion, neurotransmission", "d": ["The controlled release of orexin from a cell in which orexin acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048735", "l": "haltere morphogenesis", "d": ["The process in which the anatomical structures of a haltere are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0071450", "l": "cellular response to oxygen radical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003221", "l": "right ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061016", "l": "snRNA localization to Cajal body", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0015947", "l": "methane metabolic process", "d": ["The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034295", "l": "basidiospore formation", "d": ["The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032245", "l": "regulation of purine nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048371", "l": "lateral mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990577", "l": "C-terminal protein demethylation", "d": ["The removal of a methyl group from the C-terminal amino acid of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021592", "l": "fourth ventricle development", "d": ["The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043137", "l": "DNA replication, removal of RNA primer", "d": ["Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097377", "l": "spinal cord interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905558", "l": "negative regulation of mitotic nuclear envelope disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043122", "l": "regulation of canonical NF-kappaB signal transduction", "d": ["Any process that modulates the canonical NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010902", "l": "positive regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080153", "l": "negative regulation of reductive pentose-phosphate cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903376", "l": "regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0090231", "l": "regulation of spindle checkpoint", "d": ["Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031631", "l": "negative regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018980", "l": "2,4,5-trichlorophenoxyacetic acid metabolic process", "d": ["The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001278", "l": "positive regulation of leucine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022620", "l": "microgametophyte vegetative cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902128", "l": "(-)-lariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140873", "l": "paxilline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902759", "l": "Mo(VI)-molybdopterin cytosine dinucleotide metabolic process", "d": ["The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002310", "l": "alpha-beta T cell proliferation involved in immune response", "d": ["The expansion of an alpha-beta T cell population by cell division as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000375", "l": "negative regulation of oxygen metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0018197", "l": "peptidyl-aspartic acid modification", "d": ["The modification of peptidyl-aspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097053", "l": "L-kynurenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036167", "l": "phenotypic switching in response to host", "d": ["A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000815", "l": "regulation of mRNA stability involved in response to oxidative stress", "d": ["A process of regulation of mRNA stability that is involved in a response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021560", "l": "abducens nerve development", "d": ["The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003238", "l": "conus arteriosus development", "d": ["The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090399", "l": "replicative senescence", "d": ["A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032246", "l": "regulation of pyrimidine nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904252", "l": "negative regulation of bile acid metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075245", "l": "positive regulation of oospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072136", "l": "metanephric mesenchymal cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032347", "l": "regulation of aldosterone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903688", "l": "positive regulation of border follicle cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of border follicle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015950", "l": "purine nucleotide interconversion", "d": ["The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0035435", "l": "phosphate ion transmembrane transport", "d": ["The process in which a phosphate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046053", "l": "dAMP metabolic process", "d": ["The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006523", "l": "alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0003401", "l": "axis elongation", "d": ["The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904034", "l": "positive regulation of t-SNARE clustering", "d": ["Any process that activates or increases the frequency, rate or extent of t-SNARE clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900681", "l": "octadecene metabolic process", "d": ["The chemical reactions and pathways involving octadecene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033050", "l": "clavulanic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018920", "l": "glyphosate metabolic process", "d": ["The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007563", "l": "regulation of eclosion", "d": ["Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904477", "l": "positive regulation of small GTPase binding", "d": ["Any process that activates or increases the frequency, rate or extent of small GTPase binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900933", "l": "negative regulation of nonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007112", "l": "male meiosis cytokinesis", "d": ["A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900079", "l": "regulation of arginine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of arginine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070316", "l": "regulation of G0 to G1 transition", "d": ["A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042554", "l": "superoxide anion generation", "d": ["The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120276", "l": "regulation of cerebral blood circulation", "d": ["Any process that modulates the frequency, rate or extent of cerebral blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045704", "l": "regulation of salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000405", "l": "negative regulation of T cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902311", "l": "regulation of copper ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of copper ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990863", "l": "acinar cell proliferation", "d": ["The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051289", "l": "protein homotetramerization", "d": ["The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:1903664", "l": "regulation of asexual reproduction", "d": ["Any process that modulates the frequency, rate or extent of asexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000180", "l": "negative regulation of androgen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904351", "l": "negative regulation of protein catabolic process in the vacuole", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016334", "l": "establishment or maintenance of polarity of follicular epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019333", "l": "denitrification pathway", "d": ["The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052864", "l": "1-deoxy-D-xylulose 5-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902980", "l": "synthesis of RNA primer involved in premeiotic DNA replication", "d": ["Any synthesis of RNA primer involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0060563", "l": "neuroepithelial cell differentiation", "d": ["The process in which epiblast cells acquire specialized features of neuroepithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097188", "l": "dentin mineralization", "d": ["The process in which calcium salts are deposited into the calcareous tooth structure known as dentin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010897", "l": "negative regulation of triglyceride catabolic process", "d": ["Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097155", "l": "fasciculation of sensory neuron axon", "d": ["The collection of sensory neuron axons into a bundle of rods, known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903721", "l": "positive regulation of I-kappaB phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071278", "l": "cellular response to cesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044642", "l": "envenomation resulting in modulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905679", "l": "positive regulation of adaptive immune effector response", "d": ["Any process that activates or increases the frequency, rate or extent of adaptive immune effector response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010103", "l": "stomatal complex morphogenesis", "d": ["The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022020", "l": "medial ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0016098", "l": "monoterpenoid metabolic process", "d": ["The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090296", "l": "regulation of mitochondrial DNA replication", "d": ["Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0047484", "l": "regulation of response to osmotic stress", "d": ["Any process that modulates the rate or extent of the response to osmotic stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001196", "l": "positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008292", "l": "acetylcholine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903330", "l": "negative regulation of iron-sulfur cluster assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000539", "l": "regulation of protein geranylgeranylation", "d": ["Any process that modulates the frequency, rate or extent of protein geranylgeranylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002003", "l": "angiotensin maturation", "d": ["The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008295", "l": "spermidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120030", "l": "positive regulation of cilium beat frequency involved in ciliary motility", "d": ["Any process that activates or increases the frequency of cilium beating involved in ciliary motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019669", "l": "anaerobic glycine catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060751", "l": "branch elongation involved in mammary gland duct branching", "d": ["The developmental growth process in which a branch of a mammary gland duct elongates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032088", "l": "negative regulation of NF-kappaB transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048913", "l": "anterior lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.544126652876884", "identifiers": [{"i": "GO:0098655", "l": "monoatomic cation transmembrane transport", "d": ["The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019483", "l": "beta-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901142", "l": "insulin metabolic process", "d": ["The chemical reactions and pathways involving insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990212", "l": "positive regulation by symbiont of ethylene levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901321", "l": "positive regulation of heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of heart induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090346", "l": "cellular organofluorine metabolic process", "d": ["The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.245311748130447", "identifiers": [{"i": "GO:0045132", "l": "meiotic chromosome segregation", "d": ["The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019440", "l": "tryptophan catabolic process to indole-3-acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070245", "l": "positive regulation of thymocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902835", "l": "negative regulation of proline import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904278", "l": "positive regulation of wax biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of wax biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000806", "l": "positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046673", "l": "negative regulation of compound eye retinal cell programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052391", "l": "induction by symbiont of defense-related host calcium ion flux", "d": ["The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.240937671532407", "identifiers": [{"i": "GO:0006909", "l": "phagocytosis", "d": ["A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051999", "l": "mannosyl-inositol phosphorylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043573", "l": "leucoplast fission", "d": ["The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900145", "l": "regulation of nodal signaling pathway involved in determination of left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002127", "l": "tRNA wobble base cytosine methylation", "d": ["The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001312", "l": "lysobisphosphatidic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070054", "l": "mRNA splicing, via endonucleolytic cleavage and ligation", "d": ["Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901728", "l": "monensin A metabolic process", "d": ["The chemical reactions and pathways involving monensin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097173", "l": "N-acetylmuramic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090547", "l": "response to low humidity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051715", "l": "cytolysis in another organism", "d": ["The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048752", "l": "semicircular canal morphogenesis", "d": ["The process in which the anatomical structures of the semicircular canals are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903392", "l": "negative regulation of adherens junction organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0044060", "l": "regulation of endocrine process", "d": ["Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160029", "l": "kidney cortex tubule cell dedifferentiation", "d": ["The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000372", "l": "negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007428", "l": "primary branching, open tracheal system", "d": ["Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042986", "l": "positive regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901078", "l": "negative regulation of relaxation of muscle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070248", "l": "negative regulation of natural killer cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051696", "l": "pointed-end actin filament uncapping", "d": ["The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904266", "l": "regulation of Schwann cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071724", "l": "response to diacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097082", "l": "vascular associated smooth muscle cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035346", "l": "positive regulation of hypoxanthine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036071", "l": "N-glycan fucosylation", "d": ["The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000105", "l": "histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106045", "l": "guanine deglycation, methylglyoxal removal", "d": ["The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006726", "l": "eye pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:2000036", "l": "regulation of stem cell population maintenance", "d": ["Any process that modulates the frequency, rate or extent of stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015827", "l": "tryptophan transport", "d": ["The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018150", "l": "peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903697", "l": "negative regulation of microvillus assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.150112907583278", "identifiers": [{"i": "GO:0007610", "l": "behavior", "d": ["The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021571", "l": "rhombomere 5 development", "d": ["The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0019757", "l": "glycosinolate metabolic process", "d": ["The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900588", "l": "violaceol I metabolic process", "d": ["The chemical reactions and pathways involving violaceol I."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030853", "l": "negative regulation of granulocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090067", "l": "regulation of thalamus size", "d": ["Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042249", "l": "establishment of planar polarity of embryonic epithelium", "d": ["Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071593", "l": "lymphocyte aggregation", "d": ["The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001149", "l": "negative regulation of dipeptide transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052651", "l": "monoacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000735", "l": "positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.078122804282714", "identifiers": [{"i": "GO:0050817", "l": "coagulation", "d": ["The process in which a fluid solution, or part of it, changes into a solid or semisolid mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048873", "l": "homeostasis of number of cells within a tissue", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048734", "l": "proboscis morphogenesis", "d": ["The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903918", "l": "regulation of actin filament severing", "d": ["Any process that modulates the frequency, rate or extent of actin filament severing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021629", "l": "olfactory nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032075", "l": "positive regulation of nuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000488", "l": "maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990790", "l": "response to glial cell derived neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.85650374451339", "identifiers": [{"i": "GO:0051707", "l": "response to other organism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060879", "l": "semicircular canal fusion", "d": ["Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900029", "l": "positive regulation of ruffle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of ruffle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097294", "l": "'de novo' XMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032122", "l": "oral apparatus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000722", "l": "telomere maintenance via recombination", "d": ["Any recombinational process that contributes to the maintenance of proper telomeric length."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051295", "l": "establishment of meiotic spindle localization", "d": ["The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1905517", "l": "macrophage migration", "d": ["The orderly movement of a macrophage from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901464", "l": "negative regulation of tetrapyrrole biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061450", "l": "trophoblast cell migration", "d": ["Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106108", "l": "negative regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905794", "l": "response to puromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061684", "l": "chaperone-mediated autophagy", "d": ["The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000819", "l": "regulation of nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate or extent of nucleotide-excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904185", "l": "equatorial microtubule organizing center assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009988", "l": "cell-cell recognition", "d": ["Cell recognition between cells. May involve the formation of specialized cell junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0036003", "l": "positive regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042859", "l": "chrysobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043133", "l": "hindgut contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099148", "l": "regulation of synaptic vesicle docking", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle docking."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019548", "l": "arginine catabolic process to spermine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072042", "l": "regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048303", "l": "negative regulation of isotype switching to IgG isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000660", "l": "negative regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002846", "l": "regulation of T cell tolerance induction to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001271", "l": "negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051887", "l": "regulation of timing of exogen", "d": ["Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032785", "l": "negative regulation of DNA-templated transcription, elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045571", "l": "negative regulation of imaginal disc growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.949946563509286", "identifiers": [{"i": "GO:0006813", "l": "potassium ion transport", "d": ["The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019368", "l": "fatty acid elongation, unsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097087", "l": "interleukin-17A production", "d": ["The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071402", "l": "cellular response to lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0046888", "l": "negative regulation of hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016183", "l": "synaptic vesicle coating", "d": ["The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902552", "l": "negative regulation of catalase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035436", "l": "triose phosphate transmembrane transport", "d": ["The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075187", "l": "hyphopodium formation", "d": ["The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042467", "l": "orthokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905919", "l": "negative regulation of CoA-transferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009723", "l": "response to ethylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000009", "l": "negative regulation of protein localization to cell surface", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034412", "l": "ascospore wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0001508", "l": "action potential", "d": ["A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042320", "l": "regulation of circadian sleep/wake cycle, REM sleep", "d": ["Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006490", "l": "oligosaccharide-lipid intermediate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003116", "l": "regulation of vasoconstriction by norepinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001182", "l": "RNA polymerase I promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0045332", "l": "phospholipid translocation", "d": ["The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009292", "l": "horizontal gene transfer", "d": ["The introduction of genetic information into a cell to create a genetically different individual, without production of new individuals."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001703", "l": "gastrulation with mouth forming first", "d": ["A gastrulation process in which the initial invagination becomes the mouth and the anus forms second."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045771", "l": "negative regulation of autophagosome size", "d": ["Any process that reduces autophagosome size."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061059", "l": "positive regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050814", "l": "epothilone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060472", "l": "positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration", "d": ["Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0016106", "l": "sesquiterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006534", "l": "cysteine metabolic process", "d": ["The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031918", "l": "positive regulation of synaptic metaplasticity", "d": ["A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.381710255175513", "identifiers": [{"i": "GO:0045786", "l": "negative regulation of cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903984", "l": "positive regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018316", "l": "peptide cross-linking via L-cystine", "d": ["The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002272", "l": "plasmacytoid dendritic cell differentiation involved in immune response", "d": ["The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010100", "l": "negative regulation of photomorphogenesis", "d": ["Any process that stops, reduces or prevents photomorphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039595", "l": "induction by virus of catabolism of host mRNA", "d": ["The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035433", "l": "acetate transmembrane transport", "d": ["The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062027", "l": "positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "d": ["Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051228", "l": "mitotic spindle disassembly", "d": ["The controlled breakdown of the spindle during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044027", "l": "negative regulation of gene expression via CpG island methylation", "d": ["An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900323", "l": "positive regulation of maltotetraose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltotetraose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035151", "l": "regulation of tube size, open tracheal system", "d": ["Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901979", "l": "regulation of inward rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901556", "l": "response to candesartan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010756", "l": "positive regulation of plasminogen activation", "d": ["Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046662", "l": "regulation of egg-laying behavior", "d": ["Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070808", "l": "regulation of Hulle cell development", "d": ["Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900759", "l": "positive regulation of D-amino-acid oxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007342", "l": "fusion of sperm to egg plasma membrane involved in single fertilization", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900717", "l": "negative regulation of violaceol II biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0001819", "l": "positive regulation of cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of production of a cytokine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1990399", "l": "epithelium regeneration", "d": ["The regrowth of lost or destroyed epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903465", "l": "positive regulation of mitotic cell cycle DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090290", "l": "positive regulation of osteoclast proliferation", "d": ["Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036103", "l": "Kdo2-lipid A metabolic process", "d": ["The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030573", "l": "bile acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014709", "l": "positive regulation of somitomeric trunk muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904587", "l": "response to glycoprotein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904964", "l": "positive regulation of phytol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:1902410", "l": "mitotic cytokinetic process", "d": ["Any cytokinetic process that is involved in mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900676", "l": "negative regulation of F-9775B biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090609", "l": "single-species submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009809", "l": "lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014031", "l": "mesenchymal cell development", "d": ["The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901668", "l": "regulation of superoxide dismutase activity", "d": ["Any process that modulates the frequency, rate or extent of superoxide dismutase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.539968465286577", "identifiers": [{"i": "GO:0007507", "l": "heart development", "d": ["The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000746", "l": "regulation of defecation rhythm", "d": ["Any process that modulates the frequency, rate or extent of defecation rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060427", "l": "lung connective tissue development", "d": ["The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.140542116726714", "identifiers": [{"i": "GO:0030182", "l": "neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0052200", "l": "response to host defenses", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021707", "l": "cerebellar granule cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010944", "l": "negative regulation of transcription by competitive promoter binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905866", "l": "positive regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0061538", "l": "histamine secretion, neurotransmission", "d": ["The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.58597274768276", "identifiers": [{"i": "GO:0035929", "l": "steroid hormone secretion", "d": ["The regulated release of any steroid that acts as a hormone into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015818", "l": "isoleucine transport", "d": ["The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.598893201489091", "identifiers": [{"i": "GO:0023051", "l": "regulation of signaling", "d": ["Any process that modulates the frequency, rate or extent of a signaling process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039711", "l": "cytoplasmic helical capsid assembly", "d": ["The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051290", "l": "protein heterotetramerization", "d": ["The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039685", "l": "rolling hairpin viral DNA replication", "d": ["A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032306", "l": "regulation of prostaglandin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018303", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902000", "l": "homogentisate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homogentisate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904457", "l": "positive regulation of neuronal action potential", "d": ["Any process that activates or increases the frequency, rate or extent of neuronal action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903644", "l": "regulation of chaperone-mediated protein folding", "d": ["Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.534642734314296", "identifiers": [{"i": "GO:0043010", "l": "camera-type eye development", "d": ["The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902391", "l": "positive regulation of N-terminal peptidyl-serine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034587", "l": "piRNA processing", "d": ["A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071524", "l": "pyrrolysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903167", "l": "regulation of pyrroline-5-carboxylate reductase activity", "d": ["Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003004", "l": "follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010899", "l": "regulation of phosphatidylcholine catabolic process", "d": ["Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0098903", "l": "regulation of membrane repolarization during action potential", "d": ["Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002616", "l": "regulation of macrophage antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009728", "l": "detection of gibberellic acid stimulus", "d": ["The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905431", "l": "microcystin transport", "d": ["The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905597", "l": "positive regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018419", "l": "protein catenane formation", "d": ["The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032649", "l": "regulation of type II interferon production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048054", "l": "R2/R5 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048006", "l": "antigen processing and presentation, endogenous lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0040001", "l": "establishment of mitotic spindle localization", "d": ["The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033516", "l": "L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000205", "l": "positive regulation of ribosomal large subunit export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0051146", "l": "striated muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120191", "l": "negative regulation of termination of RNA polymerase II transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061124", "l": "positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021982", "l": "pineal gland development", "d": ["The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070367", "l": "negative regulation of hepatocyte differentiation", "d": ["Any process that stops or decreases the rate or extent of hepatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010669", "l": "epithelial structure maintenance", "d": ["A tissue homeostatic process required for the maintenance of epithelial structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061909", "l": "autophagosome-lysosome fusion", "d": ["The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901452", "l": "negative regulation of response to benzene", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905374", "l": "response to homocysteine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051904", "l": "pigment granule transport", "d": ["The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090402", "l": "oncogene-induced cell senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061056", "l": "sclerotome development", "d": ["The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036110", "l": "cellular response to inositol starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901847", "l": "nicotinate metabolic process", "d": ["The chemical reactions and pathways involving nicotinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.534642734314296", "identifiers": [{"i": "GO:0007586", "l": "digestion", "d": ["The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046775", "l": "suppression by virus of host cytokine production", "d": ["Any viral process that results in the inhibition of host cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061229", "l": "mesonephric juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0051650", "l": "establishment of vesicle localization", "d": ["The directed movement of a vesicle to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039640", "l": "viral release via suppression of host peptidoglycan biosynthetic process", "d": ["The dissemination of mature viral particles from a host cell, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042774", "l": "plasma membrane ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016557", "l": "peroxisome membrane biogenesis", "d": ["The process in which a peroxisome membrane is synthesized, aggregates, and bonds together."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.638099452297539", "identifiers": [{"i": "GO:0060255", "l": "regulation of macromolecule metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014899", "l": "cardiac muscle atrophy", "d": ["A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030840", "l": "negative regulation of intermediate filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044859", "l": "protein insertion into plasma membrane raft", "d": ["The process in which a protein is incorporated into a plasma membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0016124", "l": "xanthophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0046958", "l": "nonassociative learning", "d": ["A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099008", "l": "viral entry via permeabilization of inner membrane", "d": ["The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0098765", "l": "meiosis II cell cycle phase", "d": ["A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division)."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002360", "l": "T cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031506", "l": "cell wall glycoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.345324670587374", "identifiers": [{"i": "GO:0051094", "l": "positive regulation of developmental process", "d": ["Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018894", "l": "dibenzo-p-dioxin metabolic process", "d": ["The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042195", "l": "aerobic gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001204", "l": "regulation of osteoclast development", "d": ["Any process that modulates the frequency, rate or extent of osteoclast development."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048528", "l": "post-embryonic root development", "d": ["The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036176", "l": "response to neutral pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001231", "l": "regulation of protein localization to prospore membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to prospore membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045060", "l": "negative thymic T cell selection", "d": ["The process of elimination of immature T cells in the thymus which react strongly with self-antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903215", "l": "negative regulation of protein targeting to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070131", "l": "positive regulation of mitochondrial translation", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019760", "l": "glucosinolate metabolic process", "d": ["The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002731", "l": "negative regulation of dendritic cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.122742264235399", "identifiers": [{"i": "GO:0030902", "l": "hindbrain development", "d": ["The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060989", "l": "lipid tube assembly involved in organelle fusion", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071412", "l": "cellular response to genistein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0033003", "l": "regulation of mast cell activation", "d": ["Any process that modulates the frequency, rate, or extent of mast cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043562", "l": "cellular response to nitrogen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072554", "l": "blood vessel lumenization", "d": ["The process in which a developing blood vessel forms an endothelial lumen through which blood will flow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097706", "l": "vascular endothelial cell response to oscillatory fluid shear stress", "d": ["Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0015879", "l": "carnitine transport", "d": ["The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902179", "l": "verruculogen metabolic process", "d": ["The chemical reactions and pathways involving verruculogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007541", "l": "sex determination, primary response to X:A ratio", "d": ["The developmental process in which an organism interprets its X to autosomal chromosomal complement."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904370", "l": "regulation of protein localization to actin cortical patch", "d": ["Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1902513", "l": "regulation of organelle transport along microtubule", "d": ["Any process that modulates the frequency, rate or extent of organelle transport along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014719", "l": "skeletal muscle satellite cell activation", "d": ["The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016136", "l": "saponin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060856", "l": "establishment of blood-brain barrier", "d": ["Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030811", "l": "regulation of nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000540", "l": "negative regulation of protein geranylgeranylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.627202240952215", "identifiers": [{"i": "GO:0071310", "l": "cellular response to organic substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070642", "l": "vitamin D5 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009949", "l": "polarity specification of anterior/posterior axis", "d": ["Any process resulting in the establishment of polarity along the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902338", "l": "negative regulation of apoptotic process involved in morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019572", "l": "L-arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044382", "l": "CLRC complex localization to heterochromatin", "d": ["The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071609", "l": "chemokine (C-C motif) ligand 5 production", "d": ["The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098867", "l": "intramembranous bone growth", "d": ["The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.400129184613753", "identifiers": [{"i": "GO:0002831", "l": "regulation of response to biotic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of a response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903557", "l": "positive regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048912", "l": "glial cell migration in anterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1904035", "l": "regulation of epithelial cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006883", "l": "intracellular sodium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061205", "l": "paramesonephric duct development", "d": ["The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001153", "l": "positive regulation of renal water transport", "d": ["Any process that activates or increases the frequency, rate or extent of renal water transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042728", "l": "flavin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002634", "l": "regulation of germinal center formation", "d": ["Any process that modulates the frequency, rate, or extent of germinal center formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036035", "l": "osteoclast development", "d": ["The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904657", "l": "negative regulation of sensory perception of sweet taste", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046118", "l": "7-methylguanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007450", "l": "dorsal/ventral pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.652206388559449", "identifiers": [{"i": "GO:0062197", "l": "cellular response to chemical stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062086", "l": "regulation of vein smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of vein smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000516", "l": "positive regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990691", "l": "cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003437", "l": "regulation of cell communication involved in growth plate cartilage morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010726", "l": "positive regulation of hydrogen peroxide metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033082", "l": "regulation of extrathymic T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010452", "l": "histone H3-K36 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990603", "l": "dark adaptation", "d": ["The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0046349", "l": "amino sugar biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903824", "l": "negative regulation of telomere single strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021773", "l": "striatal medium spiny neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002115", "l": "store-operated calcium entry", "d": ["A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015709", "l": "thiosulfate transport", "d": ["The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900996", "l": "benzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060552", "l": "positive regulation of fructose 1,6-bisphosphate metabolic process", "d": ["Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060752", "l": "intestinal phytosterol absorption", "d": ["Any process in which phytosterols are taken up from the contents of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.365551207689407", "identifiers": [{"i": "GO:0051251", "l": "positive regulation of lymphocyte activation", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010654", "l": "apical cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904384", "l": "cellular response to sodium phosphate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061610", "l": "glycerol to glycerone phosphate metabolic process", "d": ["The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014017", "l": "neuroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045329", "l": "carnitine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0106070", "l": "regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032425", "l": "positive regulation of mismatch repair", "d": ["Any process that activates or increases the frequency, rate or extent of mismatch repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018304", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903213", "l": "protein localization to subtelomeric heterochromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901813", "l": "astaxanthin metabolic process", "d": ["The chemical reactions and pathways involving astaxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900640", "l": "regulation of austinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of austinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071481", "l": "cellular response to X-ray", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003060", "l": "negative regulation of the force of heart contraction by acetylcholine", "d": ["The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.718318631034926", "identifiers": [{"i": "GO:0050909", "l": "sensory perception of taste", "d": ["The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030962", "l": "peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine", "d": ["The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901024", "l": "4-hydroxyphenylacetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0043534", "l": "blood vessel endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901935", "l": "beta-caryophyllene metabolic process", "d": ["The chemical reactions and pathways involving beta-caryophyllene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032651", "l": "regulation of interleukin-1 beta production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 beta production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030262", "l": "apoptotic nuclear changes", "d": ["Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048254", "l": "snoRNA localization", "d": ["Any process in which small nucleolar RNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035756", "l": "transepithelial migration of symbiont in host", "d": ["The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061612", "l": "galactose to glucose-1-phosphate metabolic process", "d": ["The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043475", "l": "pigment metabolic process involved in pigment accumulation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045969", "l": "positive regulation of juvenile hormone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904639", "l": "cellular response to resveratrol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902059", "l": "negative regulation of sporocarp development involved in sexual reproduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990570", "l": "GDP-mannose transmembrane transport", "d": ["The process in which GDP-mannose is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000787", "l": "regulation of venous endothelial cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006265", "l": "DNA topological change", "d": ["The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035990", "l": "tendon cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003217", "l": "cardiac right atrium formation", "d": ["The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905324", "l": "telomere-telomerase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0050727", "l": "regulation of inflammatory response", "d": ["Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901068", "l": "guanosine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving guanosine-containing compounds (guanosines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000314", "l": "negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0003300", "l": "cardiac muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0035270", "l": "endocrine system development", "d": ["Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010808", "l": "positive regulation of synaptic vesicle priming", "d": ["Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032359", "l": "provirus excision", "d": ["The molecular events that lead to the excision of a viral genome from the host genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035652", "l": "clathrin-coated vesicle cargo loading", "d": ["Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0043370", "l": "regulation of CD4-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905064", "l": "negative regulation of vascular associated smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021724", "l": "inferior raphe nucleus development", "d": ["The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140708", "l": "CAT tailing", "d": ["The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control sytem."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046289", "l": "isoflavonoid phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019511", "l": "peptidyl-proline hydroxylation", "d": ["The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140526", "l": "double membrane vesicle viral factory assembly", "d": ["A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound 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(in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071799", "l": "cellular response to prostaglandin D stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903448", "l": "geraniol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geraniol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905192", "l": "regulation of chloroplast fission", "d": ["Any process that modulates the frequency, rate or extent of chloroplast fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": 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whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.833128032771839", "identifiers": [{"i": "GO:1901699", "l": "cellular response to nitrogen compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032730", "l": "positive regulation of interleukin-1 alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043652", "l": "engulfment of apoptotic cell", "d": ["The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097466", "l": "ubiquitin-dependent glycoprotein ERAD pathway", "d": ["An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000361", "l": "regulation of prostaglandin-E synthase activity", "d": ["Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090474", "l": "arg-arg specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904880", "l": "response to hydrogen sulfide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051581", "l": "negative regulation of neurotransmitter uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045591", "l": "positive regulation of regulatory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019479", "l": "L-alanine oxidation to D-lactate and ammonia", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052708", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process", "d": ["The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043497", "l": "regulation of protein heterodimerization activity", "d": ["Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000338", "l": "regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060159", "l": "regulation of dopamine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.769355763942954", "identifiers": [{"i": "GO:0051053", "l": "negative regulation of DNA metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045467", "l": "R7 cell development", "d": ["The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001285", "l": "negative regulation of BMP secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018160", "l": "peptidyl-pyrromethane cofactor linkage", "d": ["The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0061548", "l": "ganglion development", "d": ["The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006693", "l": "prostaglandin metabolic process", "d": ["The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002330", "l": "pre-B cell receptor expression", "d": ["The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030419", "l": "nicotianamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:2000765", "l": "regulation of cytoplasmic translation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008334", "l": "histone mRNA metabolic process", "d": ["The chemical reactions and pathways involving an mRNA encoding a histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0035296", "l": "regulation of tube diameter", "d": ["Any process that modulates the diameter of a tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904886", "l": "beta-catenin destruction complex disassembly", "d": ["The disaggregation of a beta-catenin destruction complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009253", "l": "peptidoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016135", "l": "saponin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0030488", "l": "tRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0002455", "l": "humoral immune response mediated by circulating immunoglobulin", "d": ["An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051071", "l": "4,6-pyruvylated galactose residue metabolic process", "d": ["The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.255964526479211", "identifiers": [{"i": "GO:0048870", "l": "cell motility", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.361282203588587", "identifiers": [{"i": "GO:0006906", "l": "vesicle fusion", "d": ["Fusion of the membrane of a transport vesicle with its target membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061520", "l": "Langerhans cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a Langerhans cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007214", "l": "gamma-aminobutyric acid signaling pathway", "d": ["The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021505", "l": "neural fold folding", "d": ["The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060010", "l": "Sertoli cell fate commitment", "d": ["The process in which the cellular identity of Sertoli cells is acquired and determined."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051986", "l": "negative regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904712", "l": "positive regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032436", "l": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030727", "l": "germarium-derived female germ-line cyst formation", "d": ["Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0061531", "l": "primary amine secretion", "d": ["The regulated release of a primary amine by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000550", "l": "negative regulation of B cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032416", "l": "negative regulation of sodium:proton antiporter activity", "d": ["Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905466", "l": "negative regulation of G-quadruplex DNA unwinding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050428", "l": "3'-phosphoadenosine 5'-phosphosulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032596", "l": "protein transport into membrane raft", "d": ["The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042448", "l": "progesterone metabolic process", "d": ["The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071476", "l": "cellular hypotonic response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046207", "l": "trypanothione catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0003159", "l": "morphogenesis of an endothelium", "d": ["The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0048525", "l": "negative regulation of viral process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904406", "l": "negative regulation of nitric oxide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010480", "l": "microsporocyte differentiation", "d": ["The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140781", "l": "ilicicolin H biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048924", "l": "posterior lateral line neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0015909", "l": "long-chain fatty acid transport", "d": ["The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905552", "l": "positive regulation of protein localization to endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.966366060217325", "identifiers": [{"i": "GO:0048729", "l": "tissue morphogenesis", "d": ["The process in which the anatomical structures of a tissue are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0098815", "l": "modulation of excitatory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060398", "l": "regulation of growth hormone receptor signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030244", "l": "cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905496", "l": "regulation of triplex DNA binding", "d": ["Any process that modulates the frequency, rate or extent of triplex DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900764", "l": "emericellin metabolic process", "d": ["The chemical reactions and pathways involving emericellin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071425", "l": "hematopoietic stem cell proliferation", "d": ["The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902726", "l": "positive regulation of skeletal muscle satellite cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of satellite cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0048515", "l": "spermatid differentiation", "d": ["The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905265", "l": "blasticidin S catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of blasticidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900453", "l": "negative regulation of long-term synaptic depression", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010374", "l": "stomatal complex development", "d": ["The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0021879", "l": "forebrain neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905179", "l": "negative regulation of cardiac muscle tissue regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060214", "l": "endocardium formation", "d": ["Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042501", "l": "serine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033299", "l": "secretion of lysosomal enzymes", "d": ["The controlled release of lysosomal enzymes by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900450", "l": "negative regulation of glutamate receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070833", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0006568", "l": "tryptophan metabolic process", "d": ["The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002227", "l": "innate immune response in mucosa", "d": ["Any process of the innate immune response that takes place in the mucosal tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0043449", "l": "cellular alkene metabolic process", "d": ["The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061285", "l": "mesonephric capsule development", "d": ["The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052838", "l": "thiazole metabolic process", "d": ["The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018966", "l": "styrene metabolic process", "d": ["The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0048070", "l": "regulation of developmental pigmentation", "d": ["Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002122", "l": "fear-induced aggressive behavior", "d": ["Aggressive behavior associated with attempts to flee from a threat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903862", "l": "positive regulation of oxidative phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007425", "l": "epithelial cell fate determination, open tracheal system", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000774", "l": "positive regulation of cellular senescence", "d": ["Any process that activates or increases the frequency, rate or extent of cellular senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901387", "l": "positive regulation of voltage-gated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071399", "l": "cellular response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032196", "l": "transposition", "d": ["Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0021626", "l": "central nervous system maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110108", "l": "positive regulation of imaginal disc-derived wing vein specification", "d": ["Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010438", "l": "cellular response to sulfur starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0060603", "l": "mammary gland duct morphogenesis", "d": ["The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901278", "l": "D-ribose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving D-ribose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090656", "l": "t-circle formation", "d": ["A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060889", "l": "limb basal epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990506", "l": "mitotic DNA-templated DNA replication", "d": ["A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150007", "l": "clathrin-dependent synaptic vesicle endocytosis", "d": ["Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072215", "l": "regulation of metanephros development", "d": ["Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106300", "l": "protein-DNA covalent cross-linking repair", "d": ["The removal of covalent cross-link between DNA and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072592", "l": "oxygen metabolic process", "d": ["The chemical reactions and pathways involving diatomic oxygen (O2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0180011", "l": "cytoplasmic polyadenylation", "d": ["Any process by which dormant, translationally inactive mRNAs become activated via the elongation of their poly(A) tails in the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010358", "l": "leaf shaping", "d": ["The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016336", "l": "establishment or maintenance of polarity of larval imaginal disc epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019301", "l": "rhamnose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990867", "l": "response to gastrin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048835", "l": "specification of decreased petal number", "d": ["Any process that reduces the number of petals produced in a developing flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990044", "l": "protein localization to lipid droplet", "d": ["A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902906", "l": "proteasome storage granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990401", "l": "embryonic lung development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043931", "l": "ossification involved in bone maturation", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900059", "l": "positive regulation of sulfate assimilation", "d": ["Any process that activates or increases the frequency, rate or extent of sulfate assimilation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031062", "l": "positive regulation of histone methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0015798", "l": "myo-inositol transport", "d": ["The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098718", "l": "serine import across plasma membrane", "d": ["The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007303", "l": "cytoplasmic transport, nurse cell to oocyte", "d": ["The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "28.211361767636859", "identifiers": [{"i": "GO:0048856", "l": "anatomical structure development", "d": ["The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052112", "l": "occlusion by symbiont of host xylem", "d": ["The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904985", "l": "negative regulation of quinolinate biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903701", "l": "substantia propria of cornea development", "d": ["The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071226", "l": "cellular response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032951", "l": "regulation of beta-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900066", "l": "positive regulation of ethanol catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ethanol catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071475", "l": "cellular hyperosmotic salinity response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000905", "l": "sporocarp development involved in asexual reproduction", "d": ["The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045650", "l": "negative regulation of macrophage differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000947", "l": "amino acid catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060714", "l": "labyrinthine layer formation", "d": ["The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010377", "l": "guard cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.406780700958855", "identifiers": [{"i": "GO:0015800", "l": "acidic amino acid transport", "d": ["The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031161", "l": "phosphatidylinositol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030420", "l": "establishment of competence for transformation", "d": ["The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050822", "l": "peptide stabilization", "d": ["Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900295", "l": "negative regulation of heptasaccharide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0061844", "l": "antimicrobial humoral immune response mediated by antimicrobial peptide", "d": ["An immune response against microbes mediated by anti-microbial peptides in body fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071994", "l": "phytochelatin transmembrane transport", "d": ["The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044635", "l": "positive regulation of complement activation, alternative pathway in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035747", "l": "natural killer cell chemotaxis", "d": ["The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901863", "l": "positive regulation of muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051483", "l": "terpenoid biosynthetic process, mevalonate-independent", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002400", "l": "tolerance induction in nasopharyngeal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034229", "l": "ethanolamine transport", "d": ["The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014746", "l": "regulation of tonic skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140590", "l": "effector-mediated suppression of host defense response", "d": ["A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.443926305975602", "identifiers": [{"i": "GO:0010648", "l": "negative regulation of cell communication", "d": ["Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075265", "l": "positive regulation of oogonium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045992", "l": "negative regulation of embryonic development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050820", "l": "positive regulation of coagulation", "d": ["Any process that activates or increases the frequency, rate or extent of coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052373", "l": "suppression of symbiont entry into host", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050856", "l": "regulation of T cell receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904568", "l": "cellular response to wortmannin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032527", "l": "protein exit from endoplasmic reticulum", "d": ["The directed movement of proteins from the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002538", "l": "arachidonic acid metabolite production involved in inflammatory response", "d": ["The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070414", "l": "trehalose metabolism in response to heat stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110017", "l": "cap-independent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900495", "l": "negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048197", "l": "Golgi membrane coat protein complex assembly", "d": ["The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:2000106", "l": "regulation of leukocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of leukocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0032543", "l": "mitochondrial translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032717", "l": "negative regulation of interleukin-8 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.426889726972838", "identifiers": [{"i": "GO:0001944", "l": "vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010109", "l": "regulation of photosynthesis", "d": ["Any process that modulates the frequency, rate or extent of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051947", "l": "regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050894", "l": "determination of affect", "d": ["Any process in which an emotional response is associated with a particular sensory stimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904205", "l": "negative regulation of skeletal muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900154", "l": "regulation of bone trabecula formation", "d": ["Any process that modulates the frequency, rate or extent of bone trabecula formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061557", "l": "trigeminal ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098629", "l": "trans-Golgi network membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000716", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002304", "l": "gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016063", "l": "rhodopsin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003425", "l": "establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division", "d": ["A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0061082", "l": "myeloid leukocyte cytokine production", "d": ["Any process that contributes to cytokine production by a myeloid cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061282", "l": "specification of mesonephric nephron tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034266", "l": "isopentenyl adenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0015948", "l": "methanogenesis", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042100", "l": "B cell proliferation", "d": ["The expansion of a B cell population by cell division. Follows B cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043609", "l": "regulation of carbon utilization", "d": ["Any process that modulates the frequency, rate, or extent of carbon utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0014706", "l": "striated muscle tissue development", "d": ["The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033246", "l": "positive regulation of penicillin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902199", "l": "3-methylbut-2-enoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902246", "l": "cis-abienol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cis-abienol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019625", "l": "atrazine catabolic process to cyanuric acid", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002301", "l": "CD4-positive, alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051415", "l": "microtubule nucleation by interphase microtubule organizing center", "d": ["The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901439", "l": "positive regulation of toluene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of toluene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900714", "l": "negative regulation of violaceol I biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1990849", "l": "vacuolar localization", "d": ["Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019372", "l": "lipoxygenase pathway", "d": ["The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048174", "l": "negative regulation of short-term neuronal synaptic plasticity", "d": ["A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000837", "l": "regulation of androstenedione secretion", "d": ["Any process that modulates the frequency, rate or extent of androstenedione secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901386", "l": "negative regulation of voltage-gated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0072070", "l": "loop of Henle development", "d": ["The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902255", "l": "positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019124", "l": "peptidyl-isoleucine racemization", "d": ["The racemization of peptidyl-isoleucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.84203750265889", "identifiers": [{"i": "GO:0018205", "l": "peptidyl-lysine modification", "d": ["The modification of peptidyl-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905942", "l": "regulation of formation of growth cone in injured axon", "d": ["Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071637", "l": "regulation of monocyte chemotactic protein-1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903178", "l": "positive regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0061546", "l": "tyramine secretion, neurotransmission", "d": ["The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0043094", "l": "cellular metabolic compound salvage", "d": ["Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000592", "l": "regulation of metanephric DCT cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097695", "l": "establishment of protein-containing complex localization to telomere", "d": ["The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046340", "l": "diacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000647", "l": "negative regulation of stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0071489", "l": "cellular response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043421", "l": "anthranilate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0044483", "l": "envenomation resulting in impairment of hemostasis in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090294", "l": "nitrogen catabolite activation of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032695", "l": "negative regulation of interleukin-12 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060360", "l": "negative regulation of leucine import in response to ammonium ion", "d": ["Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900733", "l": "negative regulation of polyketide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0097485", "l": "neuron projection guidance", "d": ["The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905036", "l": "positive regulation of antifungal innate immune response", "d": ["Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002068", "l": "glandular epithelial cell development", "d": ["The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062228", "l": "negative regulation of adult somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of adult somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903704", "l": "negative regulation of siRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of siRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903985", "l": "regulation of intestinal D-glucose absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001060", "l": "transcription by RNA polymerase V", "d": ["The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048853", "l": "forebrain morphogenesis", "d": ["The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061060", "l": "negative regulation of peptidoglycan recognition protein signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038098", "l": "sequestering of BMP from receptor via BMP binding", "d": ["Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036450", "l": "polyuridylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000749", "l": "positive regulation of rDNA heterochromatin formation", "d": ["Any process that activates or increases the frequency, rate or extent of rDNA heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032821", "l": "negative regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045723", "l": "positive regulation of fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032818", "l": "negative regulation of natural killer cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902512", "l": "positive regulation of apoptotic DNA fragmentation", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0015857", "l": "uracil transport", "d": ["The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046110", "l": "xanthine metabolic process", "d": ["The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070756", "l": "positive regulation of interleukin-35 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-35 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006809", "l": "nitric oxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072181", "l": "mesonephric duct formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030812", "l": "negative regulation of nucleotide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905182", "l": "positive regulation of urease activity", "d": ["Any process that activates or increases the frequency, rate or extent of urease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070900", "l": "mitochondrial tRNA modification", "d": ["The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0002254", "l": "kinin cascade", "d": ["A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048250", "l": "iron import into the mitochondrion", "d": ["The process in which iron is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904643", "l": "response to curcumin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.183278460114138", "identifiers": [{"i": "GO:0051932", "l": "synaptic transmission, GABAergic", "d": ["The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.341211163834416", "identifiers": [{"i": "GO:0090066", "l": "regulation of anatomical structure size", "d": ["Any process that modulates the size of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009609", "l": "response to symbiotic bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0072538", "l": "T-helper 17 type immune response", "d": ["An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061126", "l": "positive regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048165", "l": "fused antrum stage", "d": ["The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010433", "l": "bract morphogenesis", "d": ["The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106092", "l": "glial cell projection elongation involved in axon ensheathment", "d": ["The extension of a glial cell process or projection to wrap around an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033488", "l": "cholesterol biosynthetic process via 24,25-dihydrolanosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036112", "l": "medium-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090193", "l": "positive regulation of glomerulus development", "d": ["Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903226", "l": "positive regulation of endodermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001115", "l": "protein-DNA-RNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.774158651900613", "identifiers": [{"i": "GO:0048646", "l": "anatomical structure formation involved in morphogenesis", "d": ["The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061668", "l": "mitochondrial ribosome assembly", "d": ["The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0015675", "l": "nickel cation transport", "d": ["The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002539", "l": "prostaglandin production involved in inflammatory response", "d": ["The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0180012", "l": "co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway", "d": ["Any process involved in transcription termination-coupled 3' processing of RNA polymerase II RNA transcripts by 3' end cleavage and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional RNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0071622", "l": "regulation of granulocyte chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900637", "l": "regulation of asperfuranone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009220", "l": "pyrimidine ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902777", "l": "6-sulfoquinovose(1-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900543", "l": "negative regulation of purine nucleotide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140755", "l": "reorganization of host cellular membranes to establish sites of replication", "d": ["A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003166", "l": "bundle of His development", "d": ["The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060814", "l": "posterior mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0014805", "l": "smooth muscle adaptation", "d": ["Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042489", "l": "negative regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.484282358461357", "identifiers": [{"i": "GO:0007530", "l": "sex determination", "d": ["Any process that establishes and transmits the specification of sexual status of an individual organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010450", "l": "inflorescence meristem growth", "d": ["The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000127", "l": "positive regulation of octopamine or tyramine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.652206388559449", "identifiers": [{"i": "GO:0009895", "l": "negative regulation of catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.937454763326897", "identifiers": [{"i": "GO:1902652", "l": "secondary alcohol metabolic process", "d": ["The chemical reactions and pathways involving secondary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035884", "l": "arabinan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904037", "l": "positive regulation of epithelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0046928", "l": "regulation of neurotransmitter secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0051963", "l": "regulation of synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032496", "l": "response to lipopolysaccharide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061683", "l": "branching involved in seminal vesicle morphogenesis", "d": ["The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090644", "l": "age-related resistance", "d": ["An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033861", "l": "negative regulation of NAD(P)H oxidase activity", "d": ["Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900669", "l": "positive regulation of endocrocin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021721", "l": "superior olivary nucleus structural organization", "d": ["The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021829", "l": "oligodendrocyte cell migration from the subpallium to the cortex", "d": ["The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075266", "l": "negative regulation of oogonium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052544", "l": "defense response by callose deposition in cell wall", "d": ["Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0043695", "l": "detection of pheromone", "d": ["The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060367", "l": "sagittal suture morphogenesis", "d": ["The process in which the sagittal suture is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071641", "l": "negative regulation of macrophage inflammatory protein 1 alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0045576", "l": "mast cell activation", "d": ["The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0014044", "l": "Schwann cell development", "d": ["The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062142", "l": "L-beta-ethynylserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042152", "l": "RNA-mediated DNA recombination", "d": ["The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120164", "l": "conidium germination", "d": ["The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019601", "l": "toluene oxidation via 2-hydroxytoluene", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902965", "l": "regulation of protein localization to early endosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to early endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061043", "l": "regulation of vascular wound healing", "d": ["Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097332", "l": "response to antipsychotic drug", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010077", "l": "maintenance of inflorescence meristem identity", "d": ["The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000486", "l": "negative regulation of glutamine transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901354", "l": "response to L-canavanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, 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stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061476", "l": "response to anticoagulant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900221", "l": "regulation of amyloid-beta clearance", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904437", "l": "positive regulation of transferrin receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of transferrin receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050745", "l": "peptide cross-linking via L-cysteinyl-5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0051510", "l": "regulation of unidimensional cell growth", "d": ["Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0009617", "l": "response to bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0043937", "l": "regulation of sporulation", "d": ["Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042844", "l": "glycol metabolic process", "d": ["The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033594", "l": "response to hydroxyisoflavone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032660", "l": "regulation of interleukin-17 production", "d": ["Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070294", "l": "renal sodium ion absorption", "d": ["A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.737631657527999", "identifiers": [{"i": "GO:0048468", "l": "cell development", "d": ["The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070430", "l": "positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039525", "l": "modulation by virus of host chromatin organization", "d": ["Any process in which a virus effects a change in the organization of chromatin in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.388382942757389", "identifiers": [{"i": "GO:0140546", "l": "defense response to symbiont", "d": ["Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072389", "l": "flavin adenine dinucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0021799", "l": "cerebral cortex radially oriented cell migration", "d": ["The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0033046", "l": "negative regulation of sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904270", "l": "pyroptosome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.365551207689407", "identifiers": [{"i": "GO:0003341", "l": "cilium movement", "d": ["The directed, self-propelled movement of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046032", "l": "ADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034420", "l": "co-translational protein acetylation", "d": ["The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000714", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion, arms", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901317", "l": "regulation of flagellated sperm motility", "d": ["Any process that modulates the frequency, rate or extent of flagellated sperm motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019590", "l": "L-arabitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901545", "l": "response to raffinose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060177", "l": "regulation of angiotensin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006005", "l": "L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905337", "l": "positive regulation of aggrephagy", "d": ["Any process that activates or increases the frequency, rate or extent of aggrephagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046094", "l": "deoxyinosine metabolic process", "d": ["The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002808", "l": "regulation of antibacterial peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900606", "l": "tensidol B metabolic process", "d": ["The chemical reactions and pathways involving tensidol B."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006858", "l": "extracellular transport", "d": ["The transport of substances that occurs outside cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002574", "l": "thrombocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000543", "l": "positive regulation of gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001811", "l": "negative regulation of type I hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150021", "l": "apical dendrite morphogenesis", "d": ["The process in which the anatomical structures of an apical dendrite are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090237", "l": "regulation of arachidonic acid secretion", "d": ["Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0010970", "l": "transport along microtubule", "d": ["The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051838", "l": "cytolysis by host of symbiont cells", "d": ["The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016091", "l": "prenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018871", "l": "1-aminocyclopropane-1-carboxylate metabolic process", "d": ["The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902953", "l": "positive regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110083", "l": "positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0002791", "l": "regulation of peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent 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organism, leading to damage or temporary subversion of that tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0048489", "l": "synaptic vesicle transport", "d": ["The directed movement of synaptic vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097037", "l": "heme export", "d": ["The directed movement of heme out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075184", "l": "regulation of infection cushion formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont infection cushion formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903940", "l": "negative regulation of TORC2 signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000545", "l": "negative regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090206", "l": "negative regulation of cholesterol metabolic process", "d": ["Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045199", "l": "maintenance of epithelial cell apical/basal polarity", "d": ["The maintenance of the apicobasal polarity of an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032720", "l": "negative regulation of tumor necrosis factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097018", "l": "renal albumin absorption", "d": ["A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000141", "l": "positive regulation of octopamine signaling pathway involved in response to food", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901749", "l": "leukotriene D4 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of leukotriene D4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044813", "l": "glycolytic fermentation via PFOR pathway", "d": ["The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1901950", "l": "dense core granule transport", "d": ["The directed movement a dense core granule within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:1905332", "l": "positive regulation of morphogenesis of an epithelium", "d": ["Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000995", "l": "negative regulation of mannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002409", "l": "Langerhans cell chemotaxis", "d": ["The movement of a Langerhans cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071319", "l": "cellular response to benzoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1990504", "l": "dense core granule exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071499", "l": "cellular response to laminar fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010697", "l": "negative regulation of mitotic spindle pole body separation", "d": ["Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018141", "l": "peptide cross-linking via L-lysine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033632", "l": "regulation of cell-cell adhesion mediated by integrin", "d": ["Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0000429", "l": "carbon catabolite regulation of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0035697", "l": "CD8-positive, alpha-beta T cell extravasation", "d": ["The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035095", "l": "behavioral response to nicotine", "d": ["Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042854", "l": "eugenol metabolic process", "d": ["The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0098876", "l": "vesicle-mediated transport to the plasma membrane", "d": ["The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0071383", "l": "cellular response to steroid hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of 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sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0051250", "l": "negative regulation of lymphocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902170", "l": "cellular response to reactive nitrogen species", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001169", "l": "regulation of ATP biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ATP biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903696", "l": "protein localization to horsetail-astral microtubule array", "d": ["A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044806", "l": "G-quadruplex DNA unwinding", "d": ["The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903504", "l": "regulation of mitotic spindle checkpoint", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.933478334887518", "identifiers": [{"i": "GO:0035249", "l": "synaptic transmission, glutamatergic", "d": ["The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000296", "l": "negative regulation of hydrogen peroxide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905619", "l": "regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061145", "l": "lung smooth muscle development", "d": ["The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905152", "l": "positive regulation of voltage-gated sodium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060127", "l": "prolactin secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035218", "l": "leg disc development", "d": ["Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904681", "l": "response to 3-methylcholanthrene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090700", "l": "maintenance of plant organ identity", "d": ["The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051613", "l": "positive regulation of serotonin uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097039", "l": "protein linear polyubiquitination", "d": ["A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900089", "l": "negative regulation of inositol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071262", "l": "regulation of translational initiation in response to starvation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021716", "l": "inferior olivary nucleus structural organization", "d": ["The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905846", "l": "regulation of cellular response to oxidopamine", "d": ["Any process that modulates the frequency, rate or extent of cellular response to oxidopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021674", "l": "rhombomere 8 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905292", "l": "regulation of neural crest cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010246", "l": "rhamnogalacturonan I biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901404", "l": "regulation of tetrapyrrole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902239", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120065", "l": "pyloric antrum smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0050763", "l": "depsipeptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1901970", "l": "positive regulation of mitotic sister chromatid separation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062127", "l": "fatty acid primary amide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary fatty amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140633", "l": "CARD8 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905191", "l": "positive regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901104", "l": "tetracenomycin C metabolic process", "d": ["The chemical reactions and pathways involving tetracenomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905668", "l": "positive regulation of protein localization to endosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903457", "l": "lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010132", "l": "dhurrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030970", "l": "retrograde protein transport, ER to cytosol", "d": ["The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001289", "l": "lipid X metabolic process", "d": ["The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039519", "l": "modulation by virus of host autophagy", "d": ["Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0055002", "l": "striated muscle cell development", "d": ["The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009946", "l": "proximal/distal axis specification", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032630", "l": "interleukin-26 production", "d": ["The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0055092", "l": "sterol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sterol within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002914", "l": "regulation of central B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of central B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0019184", "l": "nonribosomal peptide biosynthetic process", "d": ["The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901005", "l": "ubiquinone-6 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ubiquinone-6."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990823", "l": "response to leukemia inhibitory factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032953", "l": "regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0071669", "l": "plant-type cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032597", "l": "B cell receptor transport into membrane raft", "d": ["The directed movement of a B cell receptor into a membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0061983", "l": "meiosis II cell cycle process", "d": ["A process that coontributes to the second meiotic division. 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Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071901", "l": "negative regulation of protein serine/threonine kinase activity", "d": ["Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021993", "l": "initiation of neural tube closure", "d": ["The process in which closure points are established at multiple points and along the neural rostrocaudal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043923", "l": "positive regulation by host of viral transcription", "d": ["Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036322", "l": "pancreatic polypeptide secretion", "d": ["The regulated release of pancreatic polypeptide (PP) from a cell. 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A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075530", "l": "establishment of latency as a linear episome", "d": ["A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097576", "l": "vacuole fusion", "d": ["Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0002890", "l": "negative regulation of immunoglobulin mediated immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900184", "l": "negative regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046968", "l": "peptide antigen transport", "d": ["The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904191", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division", "d": ["Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002550", "l": "positive regulation of plasma kallikrein-kinin cascade", "d": ["Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045994", "l": "positive regulation of translational initiation by iron", "d": ["Any process involving iron that activates or increases the rate of translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032119", "l": "sequestering of zinc ion", "d": ["The process of binding or confining zinc ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060838", "l": "lymphatic endothelial cell fate commitment", "d": ["The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035732", "l": "nitric oxide storage", "d": ["The accumulation and maintenance in cells or tissues of nitric oxide (NO). 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Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009761", "l": "CAM photosynthesis", "d": ["The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902259", "l": "regulation of delayed rectifier potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0045927", "l": "positive regulation of growth", "d": ["Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900679", "l": "negative regulation of ferricrocin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.782924002860781", "identifiers": [{"i": "GO:0001906", "l": "cell killing", "d": ["Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075239", "l": "zoospore formation", "d": ["The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.052350421872909", "identifiers": [{"i": "GO:0006753", "l": "nucleoside phosphate metabolic process", "d": ["The chemical reactions and pathways involving any phosphorylated nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000471", "l": "regulation of hematopoietic stem cell migration", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019251", "l": "anaerobic cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042187", "l": "p-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900945", "l": "negative regulation of isoprene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090598", "l": "male anatomical structure morphogenesis", "d": ["The processes by which anatomical structures that are only present in the male organism are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904334", "l": "heme import across plasma membrane", "d": ["The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061970", "l": "maintenance of right sidedness", "d": ["The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033144", "l": "negative regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070581", "l": "rolling circle DNA replication", "d": ["A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0071248", "l": "cellular response to metal ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0160063", "l": "multi-pass transmembrane protein insertion into ER membrane", "d": ["A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. 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Plasminogen activation is the process in which plasminogen is processed to plasmin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905402", "l": "regulation of activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901187", "l": "regulation of ephrin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006616", "l": "SRP-dependent cotranslational protein targeting to membrane, translocation", "d": ["The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905241", "l": "positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0050792", "l": "regulation of viral process", "d": ["Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090275", "l": "negative regulation of somatostatin secretion", "d": ["Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075281", "l": "positive regulation of uredinium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071374", "l": "cellular response to parathyroid hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043551", "l": "regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085017", "l": "entry into host cell by a symbiont-containing vacuole", "d": ["The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070979", "l": "protein K11-linked ubiquitination", "d": ["A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0060294", "l": "cilium movement involved in cell motility", "d": ["Movement of cilia mediated by motor proteins that contributes to the movement of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006240", "l": "dCDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900116", "l": "extracellular negative regulation of signal transduction", "d": ["Any negative regulation of signal transduction that takes place in extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.078122804282714", "identifiers": [{"i": "GO:0051051", "l": "negative regulation of transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042318", "l": "penicillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046011", "l": "regulation of oskar mRNA translation", "d": ["Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019631", "l": "quinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0032107", "l": "regulation of response to nutrient levels", "d": ["Any process that modulates the frequency, rate or extent of a response to nutrient levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0007566", "l": "embryo implantation", "d": ["Attachment of the blastocyst to the uterine lining."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042006", "l": "masculinization of hermaphroditic germ-line", "d": ["The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010426", "l": "DNA methylation on cytosine within a CHH sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035204", "l": "negative regulation of lamellocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007382", "l": "specification of segmental identity, maxillary segment", "d": ["The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046787", "l": "viral DNA repair", "d": ["The process of restoring viral DNA after damage or errors in replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900067", "l": "regulation of cellular response to alkaline pH", "d": ["Any process that modulates the frequency, rate or extent of cellular response to alkalinity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070393", "l": "teichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0042447", "l": "hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1990608", "l": "mitotic spindle pole body localization", "d": ["A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030980", "l": "alpha-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097676", "l": "histone H3-K36 dimethylation", "d": ["The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046663", "l": "dorsal closure, leading edge cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061232", "l": "mesonephric glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902211", "l": "regulation of prolactin signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of prolactin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007056", "l": "spindle assembly involved in female meiosis", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0086009", "l": "membrane repolarization", "d": ["The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904868", "l": "telomerase catalytic core complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.12782148120133", "identifiers": [{"i": "GO:0009887", "l": "animal organ morphogenesis", "d": ["Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035006", "l": "melanization defense response", "d": ["The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009647", "l": "skotomorphogenesis", "d": ["The control of plant growth, development, and differentiation in response to growth in darkness."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000685", "l": "positive regulation of cellular response to X-ray", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to X-ray."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000259", "l": "positive regulation of protein activation cascade", "d": ["Any process that activates or increases the frequency, rate or extent of protein activation cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010674", "l": "negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0070949", "l": "regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001805", "l": "positive regulation of type III hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0014848", "l": "urinary tract smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062112", "l": "fatty acid primary amide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid primary amide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902553", "l": "positive regulation of catalase activity", "d": ["Any process that activates or increases the frequency, rate or extent of catalase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044065", "l": "regulation of respiratory system process", "d": ["Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006751", "l": "glutathione catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0071852", "l": "fungal-type cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0055074", "l": "calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901029", "l": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000715", "l": "regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060452", "l": "positive regulation of cardiac muscle contraction", "d": ["Any process that increases the frequency, rate or extent of cardiac muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904464", "l": "regulation of matrix metallopeptidase secretion", "d": ["Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903787", "l": "negative regulation of glutathione biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120045", "l": "stereocilium maintenance", "d": ["The organization process that preserves a stereocilium in a stable functional or structural state."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097734", "l": "extracellular exosome biogenesis", "d": ["The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905071", "l": "tight junction disassembly", "d": ["The disaggregation of an tight junction into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097552", "l": "mitochondrial double-strand break repair via homologous recombination", "d": ["The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046209", "l": "nitric oxide metabolic process", "d": ["The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110140", "l": "flagellum attachment zone organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002794", "l": "regulation of antimicrobial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905845", "l": "positive regulation of cellular response to gamma radiation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903894", "l": "regulation of IRE1-mediated unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002130", "l": "wobble position ribose methylation", "d": ["The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033356", "l": "UDP-L-arabinose metabolic process", "d": ["The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090246", "l": "convergent extension involved in somitogenesis", "d": ["The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150119", "l": "negative regulation of protein localization to cell-cell junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033535", "l": "ajugose metabolic process", "d": ["The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007220", "l": "Notch receptor processing", "d": ["The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060817", "l": "inactivation of paternal X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042858", "l": "chrysobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032673", "l": "regulation of interleukin-4 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-4 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902389", "l": "ceramide 1-phosphate transport", "d": ["The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990547", "l": "mitochondrial phosphate ion transmembrane transport", "d": ["The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048506", "l": "regulation of timing of meristematic phase transition", "d": ["Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035036", "l": "sperm-egg recognition", "d": ["The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090028", "l": "positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032775", "l": "DNA methylation on adenine", "d": ["The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021853", "l": "cerebral cortex GABAergic interneuron migration", "d": ["The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090216", "l": "positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006198", "l": "cAMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046175", "l": "aldonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098849", "l": "cellular detoxification of cadmium ion", "d": ["Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904699", "l": "positive regulation of acinar cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of acinar cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000001", "l": "regulation of DNA damage checkpoint", "d": ["Any process that modulates the frequency, rate or extent of a DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034334", "l": "adherens junction maintenance", "d": ["The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160070", "l": "intracellular borate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043606", "l": "formamide metabolic process", "d": ["The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042248", "l": "maintenance of polarity of follicular epithelium", "d": ["The maintenance of an established polarized follicular epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904909", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141079", "l": "symbiont-mediated activation of host inflammasome-mediated signal transduction", "d": ["A process in which a symbiont subverts an inflammasome-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042421", "l": "norepinephrine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033305", "l": "chlorophyll a biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090060", "l": "regulation of metaxylem development", "d": ["Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0019363", "l": "pyridine nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904832", "l": "negative regulation of removal of superoxide radicals", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062120", "l": "LinE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032232", "l": "negative regulation of actin filament bundle assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106253", "l": "positive regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905137", "l": "regulation of viral DNA genome packaging via site-specific sequence recognition", "d": ["Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905285", "l": "fibrous ring of heart morphogenesis", "d": ["The developmental process by which a fibrous ring of heart is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044722", "l": "renal phosphate excretion", "d": ["The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000457", "l": "endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900650", "l": "negative regulation of dehydroaustinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017186", "l": "peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002331", "l": "pre-B cell allelic exclusion", "d": ["Expression of a single heavy chain allele during pre-B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090215", "l": "regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048138", "l": "germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045617", "l": "negative regulation of keratinocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061363", "l": "negative regulation of progesterone biosynthesis involved in luteolysis", "d": ["Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015859", "l": "intracellular nucleoside transport", "d": ["The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003115", "l": "regulation of vasoconstriction by epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904194", "l": "positive regulation of cholangiocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990986", "l": "DNA recombinase disassembly", "d": ["The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010443", "l": "meristemoid mother cell division", "d": ["The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061355", "l": "Wnt protein secretion", "d": ["The controlled release of a Wnt protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086051", "l": "membrane repolarization during Purkinje myocyte action potential", "d": ["The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098677", "l": "virion maturation", "d": ["Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009180", "l": "purine ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070060", "l": "'de novo' actin filament nucleation", "d": ["The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900702", "l": "negative regulation of orcinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050887", "l": "determination of sensory modality", "d": ["The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034390", "l": "smooth muscle cell apoptotic process", "d": ["Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031215", "l": "shell calcification", "d": ["The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048255", "l": "mRNA stabilization", "d": ["Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099069", "l": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "d": ["The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007495", "l": "visceral mesoderm-endoderm interaction involved in midgut development", "d": ["The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006740", "l": "NADPH regeneration", "d": ["A metabolic process that generates a pool of NADPH by the reduction of NADP+."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070221", "l": "sulfide oxidation, using sulfide:quinone oxidoreductase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900499", "l": "positive regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902490", "l": "regulation of sperm capacitation", "d": ["Any process that modulates the frequency, rate or extent of sperm capacitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905691", "l": "lipid droplet disassembly", "d": ["The disaggregation of a lipid particle into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904742", "l": "regulation of telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002236", "l": "detection of misfolded protein", "d": ["The series of events in which a misfolded protein stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016039", "l": "absorption of UV light", "d": ["The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0048319", "l": "axial mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the axial mesoderm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030541", "l": "plasmid partitioning", "d": ["Any process in which plasmids are segregated or distributed into daughter cells upon cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042906", "l": "xanthine transport", "d": ["The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110080", "l": "positive regulation of placenta blood vessel development", "d": ["Any process that activates or increases the frequency, rate or extent of placenta blood vessel development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030730", "l": "sequestering of triglyceride", "d": ["The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0051324", "l": "prophase", "d": ["The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061087", "l": "positive regulation of histone H3-K27 methylation", "d": ["Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010719", "l": "negative regulation of epithelial to mesenchymal transition", "d": ["Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0002698", "l": "negative regulation of immune effector process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007347", "l": "regulation of preblastoderm mitotic cell cycle", "d": ["A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034106", "l": "regulation of erythrocyte clearance", "d": ["Any process that modulates the frequency, rate, or extent of erythrocyte clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.055863066960292", "identifiers": [{"i": "GO:0023061", "l": "signal release", "d": ["The process in which a signal is secreted or discharged into the extracellular medium from a cellular source."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018901", "l": "2,4-dichlorophenoxyacetic acid metabolic process", "d": ["The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072297", "l": "specification of metanephric proximal tubule identity", "d": ["The process in which the proximal tubule of the metanephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0051306", "l": "mitotic sister chromatid separation", "d": ["The process in which sister chromatids are physically detached from each other during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044011", "l": "single-species biofilm formation on inanimate substrate", "d": ["A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0042491", "l": "inner ear auditory receptor cell differentiation", "d": ["The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0001889", "l": "liver development", "d": ["The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070731", "l": "cGMP transport", "d": ["The directed movement of cyclic GMP (cGMP), into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006288", "l": "base-excision repair, DNA ligation", "d": ["The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0045143", "l": "homologous chromosome segregation", "d": ["The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900710", "l": "regulation of tensidol B biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043326", "l": "chemotaxis to folate", "d": ["The directed movement of a motile cell or organism in response to the presence of folate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048265", "l": "response to pain", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070351", "l": "negative regulation of white fat cell proliferation", "d": ["Any process that stops or decreases the rate or extent of white fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0000423", "l": "mitophagy", "d": ["The selective autophagy process in which a mitochondrion is degraded by macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006538", "l": "glutamate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0140205", "l": "oligopeptide import across plasma membrane", "d": ["The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120113", "l": "cytoplasm to vacuole transport by the NVT pathway", "d": ["A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903027", "l": "regulation of opsonization", "d": ["Any process that modulates the frequency, rate or extent of opsonization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075217", "l": "negative regulation of spore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033184", "l": "positive regulation of histone ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903023", "l": "regulation of ascospore-type prospore membrane formation", "d": ["Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034214", "l": "protein hexamerization", "d": ["The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0170006", "l": "lipoate transmembrane transport", "d": ["The process in which lipoate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002533", "l": "lysosomal enzyme secretion involved in inflammatory response", "d": ["The regulated release of lysosomal enzymes by a cell as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046597", "l": "negative regulation of viral entry into host cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090379", "l": "secondary cell wall biogenesis involved in seed trichome differentiation", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904567", "l": "response to wortmannin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048628", "l": "myoblast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006610", "l": "ribosomal protein import into nucleus", "d": ["The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900317", "l": "positive regulation of maltopentaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltopentaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034454", "l": "microtubule anchoring at centrosome", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060450", "l": "positive regulation of hindgut contraction", "d": ["Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042268", "l": "regulation of cytolysis", "d": ["Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902986", "l": "regulation of lysine biosynthetic process via aminoadipic acid", "d": ["Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048877", "l": "homeostasis of number of retina cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075004", "l": "adhesion of symbiont spore to host", "d": ["The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060193", "l": "positive regulation of lipase activity", "d": ["Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070803", "l": "negative regulation of metula development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033345", "l": "asparagine catabolic process via L-aspartate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097528", "l": "execution phase of necroptosis", "d": ["A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903597", "l": "negative regulation of gap junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000957", "l": "regulation of cyclodextrin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071888", "l": "macrophage apoptotic process", "d": ["Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902080", "l": "regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0001952", "l": "regulation of cell-matrix adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010692", "l": "regulation of alkaline phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031001", "l": "response to brefeldin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905342", "l": "positive regulation of protein localization to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001142", "l": "nicotinate transport", "d": ["The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072241", "l": "metanephric DCT cell development", "d": ["The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090025", "l": "regulation of monocyte chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of monocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060971", "l": "embryonic heart tube left/right pattern formation", "d": ["The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002505", "l": "antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006543", "l": "glutamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905885", "l": "positive regulation of triglyceride transport", "d": ["Any process that activates or increases the frequency, rate or extent of triglyceride transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060920", "l": "cardiac pacemaker cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904671", "l": "negative regulation of cell differentiation involved in stem cell population maintenance", "d": ["Any negative regulation of cell differentiation that is involved in stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0033875", "l": "ribonucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901980", "l": "positive regulation of inward rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015733", "l": "shikimate transmembrane transport", "d": ["The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051159", "l": "D-arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021614", "l": "glossopharyngeal nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901105", "l": "tetracenomycin C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetracenomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043572", "l": "plastid fission", "d": ["The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903040", "l": "exon-exon junction complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061447", "l": "endocardial cushion cell fate specification", "d": ["The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903031", "l": "regulation of microtubule plus-end binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule plus-end binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002730", "l": "regulation of dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0080117", "l": "secondary growth", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900811", "l": "helvolic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of helvolic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015790", "l": "UDP-xylose transmembrane transport", "d": ["The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000962", "l": "positive regulation of cellooligosaccharide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019872", "l": "streptomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010289", "l": "homogalacturonan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071447", "l": "cellular response to hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0061550", "l": "cranial ganglion development", "d": ["The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120132", "l": "positive regulation of apoptotic process in bone marrow cell", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032963", "l": "collagen metabolic process", "d": ["The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071812", "l": "positive regulation of fever generation by positive regulation of prostaglandin secretion", "d": ["Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001731", "l": "formation of translation preinitiation complex", "d": ["The joining of the small ribosomal subunit, ternary complex, and mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072152", "l": "glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.638267672381467", "identifiers": [{"i": "GO:0007389", "l": "pattern specification process", "d": ["Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090239", "l": "regulation of histone H4 acetylation", "d": ["Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905798", "l": "positive regulation of intraciliary anterograde transport", "d": ["Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061977", "l": "hip joint articular cartilage development", "d": ["The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903460", "l": "mitotic DNA replication leading strand elongation", "d": ["Any leading strand elongation that is involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903421", "l": "regulation of synaptic vesicle recycling", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039523", "l": "suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009255", "l": "Entner-Doudoroff pathway through 6-phosphogluconate", "d": ["A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0000291", "l": "nuclear-transcribed mRNA catabolic process, exonucleolytic", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071376", "l": "cellular response to corticotropin-releasing hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070994", "l": "detection of oxidative stress", "d": ["The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071420", "l": "cellular response to histamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009207", "l": "purine ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071327", "l": "cellular response to trehalose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019357", "l": "nicotinate nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071990", "l": "maintenance of protein location to spindle pole body", "d": ["Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0048640", "l": "negative regulation of developmental growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905768", "l": "negative regulation of double-stranded telomeric DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905610", "l": "regulation of mRNA cap binding", "d": ["Any process that modulates the frequency, rate or extent of mRNA cap binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.838792909372728", "identifiers": [{"i": "GO:0099536", "l": "synaptic signaling", "d": ["Cell-cell signaling to, from or within a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0015706", "l": "nitrate transmembrane transport", "d": ["The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900660", "l": "positive regulation of emericellamide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0042335", "l": "cuticle development", "d": ["The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001134", "l": "methane biosynthetic process from carbon monoxide", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904125", "l": "convergent extension involved in rhombomere morphogenesis", "d": ["Any convergent extension that is involved in rhombomere morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071602", "l": "phytosphingosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075039", "l": "establishment of turgor in appressorium", "d": ["The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010730", "l": "negative regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061911", "l": "amphisome-lysosome fusion", "d": ["The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905373", "l": "ceramide phosphoethanolamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010592", "l": "positive regulation of lamellipodium assembly", "d": ["Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035513", "l": "oxidative RNA demethylation", "d": ["The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.971939425398659", "identifiers": [{"i": "GO:1901575", "l": "organic substance catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071830", "l": "triglyceride-rich lipoprotein particle clearance", "d": ["The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051350", "l": "negative regulation of lyase activity", "d": ["Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905140", "l": "regulation of apical ectodermal ridge formation", "d": ["Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:1902475", "l": "L-alpha-amino acid transmembrane transport", "d": ["The directed movement of L-alpha-amino acid across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032434", "l": "regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905806", "l": "regulation of synapse pruning", "d": ["Any process that modulates the frequency, rate or extent of synapse pruning."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001550", "l": "ovarian cumulus expansion", "d": ["Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050888", "l": "determination of stimulus location", "d": ["The determination of where on the body surface, within the body or in the environment a stimulus originates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014817", "l": "skeletal muscle satellite cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090519", "l": "anoxia protection", "d": ["Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903132", "l": "regulation of tube lumen cavitation", "d": ["Any process that modulates the frequency, rate or extent of tube lumen cavitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045770", "l": "positive regulation of asymmetric cell division", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003168", "l": "Purkinje myocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:1902750", "l": "negative regulation of cell cycle G2/M phase transition", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903535", "l": "negative regulation of lactose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902202", "l": "regulation of hepatocyte growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0040014", "l": "regulation of multicellular organism growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019374", "l": "galactolipid metabolic process", "d": ["The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0001806", "l": "type IV hypersensitivity", "d": ["An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002152", "l": "bile acid conjugation", "d": ["The process in which bile acids are covalently linked to taurine or glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905142", "l": "positive regulation of apical ectodermal ridge formation", "d": ["Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000913", "l": "preprophase band assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032938", "l": "negative regulation of translation in response to oxidative stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.449595639185496", "identifiers": [{"i": "GO:0070925", "l": "organelle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043651", "l": "linoleic acid metabolic process", "d": ["The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061555", "l": "ganglion structural organization", "d": ["The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903677", "l": "regulation of cap-independent translational initiation", "d": ["Any process that modulates the frequency, rate or extent of cap-independent translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042358", "l": "thiamine diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900108", "l": "negative regulation of nodal signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901094", "l": "negative regulation of protein homotetramerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003420", "l": "regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901594", "l": "response to capsazepine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009963", "l": "positive regulation of flavonoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044365", "l": "envenomation resulting in modulation of platelet aggregation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071930", "l": "negative regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that stop, prevents or decreases transcription as part of 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"d": ["The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010144", "l": "pyridoxal phosphate biosynthetic process from pyridoxamine", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902461", "l": "negative regulation of mesenchymal stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019403", "l": "galactitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.243216542573208", "identifiers": [{"i": "GO:0044085", "l": "cellular component biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009271", "l": "phage shock", "d": ["A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.326385679795735", "identifiers": [{"i": "GO:0120039", "l": "plasma membrane bounded cell projection morphogenesis", "d": ["The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0016344", "l": "meiotic chromosome movement towards spindle pole", "d": ["The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099048", "l": "CRISPR-cas system", "d": ["A defense response of that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010866", "l": "regulation of triglyceride biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070327", "l": "thyroid hormone transport", "d": ["The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905350", "l": "Y-shaped link assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900191", "l": "negative regulation of single-species biofilm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001743", "l": "lens placode formation", "d": ["The initial developmental process that will lead to the formation of an eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901107", "l": "granaticin metabolic process", "d": ["The chemical reactions and pathways involving granaticin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097580", "l": "intracellular sequestering of copper ion", "d": ["The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0008204", "l": "ergosterol metabolic process", "d": ["The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097438", "l": "exit from dormancy", "d": ["The dormancy process that results in exit from dormancy. 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Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002284", "l": "myeloid dendritic cell differentiation involved in immune response", "d": ["The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0042364", "l": "water-soluble vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033389", "l": "putrescine biosynthetic process from arginine, using agmatinase", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016259", "l": "selenocysteine metabolic process", "d": ["The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.149273381153577", "identifiers": [{"i": "GO:0070661", "l": "leukocyte proliferation", "d": ["The expansion of a leukocyte population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046721", "l": "formic acid secretion", "d": ["The controlled release of formic acid, HCOOH, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072053", "l": "renal inner medulla development", "d": ["The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018405", "l": "protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine", "d": ["Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043093", "l": "FtsZ-dependent cytokinesis", "d": ["A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904793", "l": "regulation of euchromatin binding", "d": ["Any process that modulates the frequency, rate or extent of euchromatin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006036", "l": "cuticle chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150139", "l": "positive regulation of interleukin-37 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-37 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021794", "l": "thalamus development", "d": ["The process in which the thalamus changes over time, from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000933", "l": "regulation of cellotriose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellotriose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0019884", "l": "antigen processing and presentation of exogenous antigen", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060355", "l": "positive regulation of cell adhesion molecule production", "d": ["Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900907", "l": "positive regulation of hexadecanal metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034217", "l": "ascospore wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034153", "l": "positive regulation of toll-like receptor 6 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021580", "l": "medulla oblongata formation", "d": ["The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033485", "l": "cyanidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042103", "l": "positive regulation of T cell homeostatic proliferation", "d": ["Any process that activates or increases the rate or extent of resting T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000651", "l": "positive regulation of sodium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044079", "l": "modulation by symbiont of host neurotransmitter secretion", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048200", "l": "Golgi transport vesicle coating", "d": ["The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046414", "l": "organomercury biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0051236", "l": "establishment of RNA localization", "d": ["The directed movement of RNA to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905667", "l": "negative regulation of protein localization to endosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044467", "l": "glial cell-derived neurotrophic factor production", "d": ["The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902626", "l": "assembly of large subunit precursor of preribosome", "d": ["The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903702", "l": "esophagus development", "d": ["The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0043550", "l": "regulation of lipid kinase activity", "d": ["Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009151", "l": "purine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048849", "l": "neurohypophysis formation", "d": ["The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022034", "l": "rhombomere cell proliferation", "d": ["The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006896", "l": "Golgi to vacuole transport", "d": ["The directed movement of substances from the Golgi to the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903661", "l": "positive regulation of complement-dependent cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0009163", "l": "nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048345", "l": "regulation of paraxial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904900", "l": "negative regulation of myosin II filament organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.58597274768276", "identifiers": [{"i": "GO:0010563", "l": "negative regulation of phosphorus metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905390", "l": "cellular response to leukotriene B4", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0061245", "l": "establishment or maintenance of bipolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034252", "l": "negative regulation of amide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002463", "l": "central tolerance induction to nonself antigen", "d": ["Tolerance induction to nonself antigens in the central lymphoid organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042836", "l": "D-glucarate metabolic process", "d": ["The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903419", "l": "protein localization to cortical endoplasmic reticulum", "d": ["A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.491863471761647", "identifiers": [{"i": "GO:0001820", "l": "serotonin secretion", "d": ["The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000496", "l": "negative regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905570", "l": "positive regulation of ferrichrome biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140124", "l": "positive regulation of Lewy body formation", "d": ["Any process that activates or increases the frequency, rate or extent of Lewy body formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009125", "l": "nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.164307912167025", "identifiers": [{"i": "GO:0002520", "l": "immune system development", "d": ["The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016319", "l": "mushroom body development", "d": ["The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018388", "l": "N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine", "d": ["The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0014812", "l": "muscle cell migration", "d": ["The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000054", "l": "negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0046122", "l": "purine deoxyribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046104", "l": "thymidine metabolic process", "d": ["The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0099402", "l": "plant organ development", "d": ["Development of a plant organ, a multi-tissue plant structure that forms a functional unit."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098761", "l": "cellular response to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0060027", "l": "convergent extension involved in gastrulation", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042862", "l": "achromobactin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035347", "l": "negative regulation of hypoxanthine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140971", "l": "regulation of AIM2 inflammasome complex assembly", "d": ["Any process that modulates the frequency, rate or extent of AIM2 inflammasome complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090657", "l": "telomeric loop disassembly", "d": ["The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048441", "l": "petal development", "d": ["The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061816", "l": "proteaphagy", "d": ["The selective autophagy process that clears 26S proteasomes; 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They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007632", "l": "visual behavior", "d": ["The behavior of an organism in response to a visual stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903298", "l": "negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009606", "l": "tropism", "d": ["The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048289", "l": "isotype switching to IgE isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015912", "l": "short-chain fatty acid transport", "d": ["The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904730", "l": "negative regulation of intestinal lipid absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060416", "l": "response to growth hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090594", "l": "inflammatory response to wounding", "d": ["The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043098", "l": "purine deoxyribonucleoside salvage", "d": ["Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0046456", "l": "icosanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042138", "l": "meiotic DNA double-strand break formation", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006569", "l": "tryptophan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061160", "l": "regulation of establishment of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032995", "l": "regulation of fungal-type cell wall biogenesis", "d": ["Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071302", "l": "cellular response to vitamin B2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.308723101263944", "identifiers": [{"i": "GO:0019637", "l": "organophosphate metabolic process", "d": ["The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900492", "l": "negative regulation of [4Fe-4S] cluster assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009849", "l": "tryptophan-independent indoleacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071352", "l": "cellular response to interleukin-2", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0016567", "l": "protein ubiquitination", "d": ["The process in which one or more ubiquitin groups are added to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039005", "l": "specification of pronephric tubule identity", "d": ["The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0086046", "l": "membrane depolarization during SA node cell action potential", "d": ["The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019570", "l": "L-arabinose catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904459", "l": "negative regulation of substance P secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901951", "l": "regulation of anterograde dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of anterograde dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.198535815504115", "identifiers": [{"i": "GO:0032506", "l": "cytokinetic process", "d": ["A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905793", "l": "protein localization to pericentriolar material", "d": ["A process in which a protein is transported to, or maintained in, a location within a pericentriolar material."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905555", "l": "positive regulation of blood vessel branching", "d": ["Any process that activates or increases the frequency, rate or extent of 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"d": ["A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030201", "l": "heparan sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072160", "l": "nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036022", "l": "limb joint morphogenesis", "d": ["The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002069", "l": "columnar/cuboidal epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. 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The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019608", "l": "nicotine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110024", "l": "positive regulation of cardiac muscle myoblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006225", "l": "UDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034179", "l": "regulation of toll-like receptor 13 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033024", "l": "mast cell apoptotic process", "d": ["Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051291", "l": "protein heterooligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. 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Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036099", "l": "female germ-line stem cell population maintenance", "d": ["The process by which an organism or tissue maintains a population of female germ-line stem cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0060675", "l": "ureteric bud morphogenesis", "d": ["The process in which the ureteric bud is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904267", "l": "negative regulation of Schwann cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0046785", "l": "microtubule polymerization", "d": ["The addition of tubulin heterodimers to one or both ends of a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009137", "l": "purine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060100", "l": "positive regulation of phagocytosis, engulfment", "d": ["Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0007320", "l": "insemination", "d": ["The introduction of semen or sperm into the genital tract of a female."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033323", "l": "choline biosynthetic process via CDP-choline", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051230", "l": "spindle disassembly", "d": ["The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075193", "l": "regulation of haustorium mother cell formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. 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biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044559", "l": "envenomation resulting in modulation of voltage-gated potassium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000829", "l": "negative regulation of parathyroid hormone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035707", "l": "T-helper 2 cell chemotaxis", "d": ["The directed movement of a T-helper 2 cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903491", "l": "response to simvastatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003261", "l": "cardiac muscle progenitor cell migration to the midline involved in heart field formation", "d": ["The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022032", "l": "telencephalon oligodendrocyte cell migration", "d": ["The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016335", "l": "morphogenesis of larval imaginal disc epithelium", "d": ["The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048206", "l": "vesicle targeting, cis-Golgi to rough endoplasmic reticulum", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072375", "l": "medium-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0039017", "l": "pattern specification involved in pronephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990793", "l": "substance P secretion, neurotransmission", "d": ["The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:1902532", "l": "negative regulation of intracellular signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019371", "l": "cyclooxygenase pathway", "d": ["The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046081", "l": "dUTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110073", "l": "regulation of apical constriction involved in ventral furrow formation", "d": ["Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018396", "l": "peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine", "d": ["The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015729", "l": "oxaloacetate transport", "d": ["The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070830", "l": "bicellular tight junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0002312", "l": "B cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0050932", "l": "regulation of pigment cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pigmented cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090049", "l": "regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061237", "l": "convergent extension involved in mesonephric nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046441", "l": "D-lysine metabolic process", "d": ["The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060212", "l": "negative regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010050", "l": "vegetative phase change", "d": ["Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0022007", "l": "convergent extension involved in neural plate elongation", "d": ["The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903375", "l": "facioacoustic ganglion development", "d": ["The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000918", "l": "regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002075", "l": "somitomeric trunk muscle development", "d": ["The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904731", "l": "positive regulation of intestinal lipid absorption", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010920", "l": "negative regulation of inositol phosphate biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0019646", "l": "aerobic electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904466", "l": "positive regulation of matrix metallopeptidase secretion", "d": ["Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062236", "l": "ionocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033092", "l": "positive regulation of immature T cell proliferation in thymus", "d": ["Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0086064", "l": "cell communication by electrical coupling involved in cardiac conduction", "d": ["The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0090288", "l": "negative regulation of cellular response to growth factor stimulus", "d": ["Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0099022", "l": "vesicle tethering", "d": ["The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0039537", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the host viral-induced cytoplasmic pattern recognition receptor signaling pathway. This is a mechanism by which the virus evades the host innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090365", "l": "regulation of mRNA modification", "d": ["Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036415", "l": "regulation of tRNA stability", "d": ["Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051984", "l": "positive regulation of chromosome segregation", "d": ["Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072733", "l": "response to staurosporine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034413", "l": "ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021665", "l": "rhombomere 5 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902437", "l": "positive regulation of male mating behavior", "d": ["Any process that activates or increases the frequency, rate or extent of male mating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.748105804263417", "identifiers": [{"i": "GO:0022404", "l": "molting cycle process", "d": ["A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043646", "l": "cephalosporin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021662", "l": "rhombomere 4 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900993", "l": "(-)-secologanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-secologanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0090500", "l": "endocardial cushion to mesenchymal transition", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120215", "l": "positive regulation of histidine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003314", "l": "heart rudiment morphogenesis", "d": ["The process in which the anatomical structures of the heart rudiment are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0031268", "l": "pseudopodium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001015", "l": "negative regulation of skeletal muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032962", "l": "positive regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072303", "l": "positive regulation of glomerular metanephric mesangial cell proliferation", "d": ["Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071348", "l": "cellular response to interleukin-11", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0007040", "l": "lysosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090258", "l": "negative regulation of mitochondrial fission", "d": ["Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904281", "l": "positive regulation of transcription by RNA polymerase V", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048883", "l": "neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0007338", "l": "single fertilization", "d": ["The union of male and female gametes to form a zygote."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003324", "l": "pancreatic D cell development", "d": ["The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097174", "l": "1,6-anhydro-N-acetyl-beta-muramic acid metabolic process", "d": ["The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.089964162112025", "identifiers": [{"i": "GO:0003016", "l": "respiratory system process", "d": ["A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.285654677908852", "identifiers": [{"i": "GO:1902600", "l": "proton transmembrane transport", "d": ["The directed movement of a proton across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071729", "l": "beak morphogenesis", "d": ["The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046725", "l": "negative regulation by virus of viral protein levels in host cell", "d": ["Any process where the infecting virus reduces the levels of viral proteins in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902701", "l": "pentose catabolic process to propan-2-ol", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000884", "l": "glucomannan catabolic process", "d": ["The chemical reactions and pathways 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component."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000517", "l": "regulation of T-helper 1 cell activation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:1903034", "l": "regulation of response to wounding", "d": ["Any process that modulates the frequency, rate or extent of response to wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902753", "l": "negative regulation of renal amino acid absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002211", "l": "behavioral defense response to insect", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901348", "l": "positive regulation of secondary cell wall biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035166", "l": "post-embryonic hemopoiesis", "d": ["The stages of blood cell formation that take place after completion of embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902004", "l": "positive regulation of amyloid-beta formation", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid-beta formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001229", "l": "negative regulation of response to gamma radiation", "d": ["Any process that stops, 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160040", "l": "mitocytosis", "d": ["A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098887", "l": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031223", "l": "auditory behavior", "d": ["The behavior of an organism in response to a sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900176", "l": "negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060381", "l": "positive regulation of single-stranded telomeric DNA binding", "d": ["Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0002902", "l": "regulation of B cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of B cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901273", "l": "2-dehydro-3-deoxy-D-gluconic acid catabolic process", "d": ["The chemical reactions and 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"identifiers": [{"i": "GO:0051552", "l": "flavone metabolic process", "d": ["The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044516", "l": "positive regulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071591", "l": "nicotinic acid riboside metabolic process", "d": ["The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905266", "l": "blasticidin S biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of blasticidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000437", "l": "regulation of monocyte extravasation", "d": ["Any process that modulates the frequency, rate or extent of monocyte extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:1902930", "l": "regulation of alcohol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of alcohol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071559", "l": "response to transforming growth factor beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042357", "l": "thiamine diphosphate metabolic process", "d": ["The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0051985", "l": "negative regulation of chromosome segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:2001252", "l": "positive regulation of chromosome organization", "d": ["Any process that activates or increases the frequency, rate 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The membranous septum is the upper part of ventricular septum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001306", "l": "lipoxin B4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071344", "l": "diphosphate metabolic process", "d": ["The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061724", "l": "lipophagy", "d": ["The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007508", "l": "larval heart development", "d": ["The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032193", "l": "ubiquinone biosynthetic process via 2-polyprenylphenol", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052576", "l": "carbohydrate storage", "d": ["The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061921", "l": "peptidyl-lysine propionylation", "d": ["The propionylation of peptidyl-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090125", "l": "cell-cell adhesion involved in synapse maturation", "d": ["The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071232", "l": "cellular response to histidine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904808", "l": "positive regulation of protein oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of protein oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903497", "l": "cellular response to 11-deoxycorticosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035206", "l": "regulation of hemocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150145", "l": "positive regulation of CD80 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072656", "l": "maintenance of protein location in mitochondrion", "d": ["Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902648", "l": "positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905625", "l": "negative regulation of L-methionine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010031", "l": "circumnutation", "d": ["The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010930", "l": "negative regulation of auxin mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0046365", "l": "monosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044758", "l": "modulation by symbiont of host synaptic transmission", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071467", "l": "cellular response to pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901901", "l": "regulation of protein localization to cell division site involved in cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.761895506129477", "identifiers": [{"i": "GO:0055080", "l": "monoatomic cation homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903548", "l": "negative regulation of growth hormone activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070684", "l": "seminal clot liquefaction", "d": ["The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019618", "l": "protocatechuate catabolic process, ortho-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090359", "l": "negative regulation of abscisic acid biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035848", "l": "oviduct morphogenesis", "d": ["The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000413", "l": "protein peptidyl-prolyl isomerization", "d": ["The modification of a protein by cis-trans isomerization of a proline residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903166", "l": "cellular response to polycyclic arene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032633", "l": "interleukin-4 production", "d": ["The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051497", "l": "negative regulation of stress fiber assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0043470", "l": "regulation of carbohydrate catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018008", "l": "N-terminal peptidyl-glycine N-myristoylation", "d": ["The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0042594", "l": "response to starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006212", "l": "uracil catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010122", "l": "arginine catabolic process to alanine via ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033860", "l": "regulation of NAD(P)H oxidase activity", "d": ["Any process that modulates the activity of the enzyme NAD(P)H oxidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010106", "l": "cellular response to iron ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902994", "l": "regulation of phospholipid efflux", "d": ["Any process that modulates the frequency, rate or extent of phospholipid efflux."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140548", "l": "envenomation resulting in blood agglutination in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905428", "l": "regulation of plant organ formation", "d": ["Any process that modulates the frequency, rate or extent of plant organ formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045659", "l": "negative regulation of neutrophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090376", "l": "seed trichome differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061101", "l": "neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007119", "l": "budding cell isotropic bud growth", "d": ["Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021742", "l": "abducens nucleus development", "d": ["The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140923", "l": "magnetosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061170", "l": "negative regulation of hair follicle placode formation", "d": ["Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0031168", "l": "ferrichrome metabolic process", "d": ["The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0000470", "l": "maturation of LSU-rRNA", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000420", "l": "negative regulation of eosinophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901295", "l": "regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0055021", "l": "regulation of cardiac muscle tissue growth", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046146", "l": "tetrahydrobiopterin metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904445", "l": "negative regulation of establishment of Sertoli cell barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905447", "l": "negative regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055063", "l": "sulfate ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006658", "l": "phosphatidylserine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0039019", "l": "pronephric nephron development", "d": ["The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090268", "l": "activation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072674", "l": "multinuclear osteoclast differentiation", "d": ["The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090348", "l": "regulation of cellular organofluorine metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900574", "l": "emodin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emodin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904966", "l": "positive regulation of vitamin E biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051412", "l": "response to corticosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021844", "l": "interneuron sorting involved in substrate-independent cerebral cortex tangential migration", "d": ["The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060735", "l": "regulation of eIF2 alpha phosphorylation by dsRNA", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060815", "l": "regulation of translation involved in anterior/posterior axis specification", "d": ["Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000156", "l": "regulation of retrograde vesicle-mediated transport, Golgi to ER", "d": ["Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051331", "l": "meiotic G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002856", "l": "negative regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000615", "l": "regulation of histone H3-K9 acetylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0048520", "l": "positive regulation of behavior", "d": ["Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150094", "l": "amyloid-beta clearance by cellular catabolic process", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002659", "l": "negative regulation of peripheral tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990515", "l": "3' transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001991", "l": "regulation of systemic arterial blood pressure by circulatory renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031035", "l": "myosin filament disassembly", "d": ["The disassembly of a filament composed of myosin molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060460", "l": "left lung morphogenesis", "d": ["The process in which anatomical structures of the left lung are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030321", "l": "transepithelial chloride transport", "d": ["The directed movement of chloride ions from one side of an epithelium to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0045860", "l": "positive regulation of protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:1901991", "l": "negative regulation of mitotic cell cycle phase transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140530", "l": "MCM complex loading", "d": ["The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071768", "l": "mycolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905388", "l": "cellular response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905083", "l": "negative regulation of mitochondrial translational elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902340", "l": "negative regulation of chromosome condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071372", "l": "cellular response to follicle-stimulating hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003408", "l": "optic cup formation involved in camera-type eye development", "d": ["The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046827", "l": "positive regulation of protein export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0071604", "l": "transforming growth factor beta production", "d": ["The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904669", "l": "ATP export", "d": ["The directed movement of ATP out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900181", "l": "negative regulation of protein localization to nucleus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046984", "l": "regulation of hemoglobin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903292", "l": "protein localization to Golgi membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001514", "l": "selenocysteine incorporation", "d": ["The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019743", "l": "hopanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071502", "l": "cellular response to temperature stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030589", "l": "pseudocleavage involved in syncytial blastoderm formation", "d": ["Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021502", "l": "neural fold elevation formation", "d": ["The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098824", "l": "peptidyl-cysteine sulfation", "d": ["The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010519", "l": "negative regulation of phospholipase activity", "d": ["Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001261", "l": "negative regulation of semaphorin-plexin signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000758", "l": "positive regulation of peptidyl-lysine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099608", "l": "regulation of action potential firing pattern", "d": ["Any process that regulates the temporal pattern of a sequence of action potentials in a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903434", "l": "negative regulation of constitutive secretory pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150190", "l": "negative regulation of interleukin-32 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990402", "l": "embryonic liver development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904589", "l": "regulation of protein import", "d": ["Any process that modulates the frequency, rate or extent of protein import."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035277", "l": "spiracle morphogenesis, open tracheal system", "d": ["The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019352", "l": "protoporphyrinogen IX biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032598", "l": "B cell receptor transport into immunological synapse", "d": ["The directed movement of a B cell receptor into an immunological synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1990179", "l": "protein localization to actomyosin contractile ring", "d": ["A process in which a protein is transported to, or maintained at, the actomyosin contractile ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0032292", "l": "peripheral nervous system axon ensheathment", "d": ["The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045022", "l": "early endosome to late endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0010632", "l": "regulation of epithelial cell migration", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0030101", "l": "natural killer cell activation", "d": ["The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.577298431659159", "identifiers": [{"i": "GO:0061982", "l": "meiosis I cell cycle process", "d": ["A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060858", "l": "vesicle-mediated transport involved in floral organ abscission", "d": ["The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0007032", "l": "endosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006107", "l": "oxaloacetate metabolic process", "d": ["The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097742", "l": "de novo centriole assembly", "d": ["Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000920", "l": "positive regulation of glucuronoarabinoxylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060335", "l": "positive regulation of type II interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002543", "l": "activation of blood coagulation via clotting cascade", "d": ["Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905169", "l": "regulation of protein localization to phagocytic vesicle", "d": ["Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007260", "l": "tyrosine phosphorylation of STAT protein", "d": ["The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034111", "l": "negative regulation of homotypic cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990767", "l": "prostaglandin receptor internalization", "d": ["The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045677", "l": "negative regulation of R7 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051410", "l": "detoxification of nitrogen compound", "d": ["Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045010", "l": "actin nucleation", "d": ["The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. 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Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072461", "l": "response to meiotic recombination checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904540", "l": "positive regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000366", "l": "intergenic mRNA trans splicing", "d": ["The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:1901379", "l": "regulation of potassium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060574", "l": "intestinal epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006924", "l": "activation-induced cell death of T cells", "d": ["A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903540", "l": "establishment of protein localization to postsynaptic membrane", "d": ["The directed movement of a protein to a specific location in a postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090377", "l": "seed trichome initiation", "d": ["The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048085", "l": "adult chitin-containing cuticle pigmentation", "d": ["Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. 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Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021946", "l": "deep nuclear neuron cell migration", "d": ["The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0044409", "l": "entry into host", "d": ["Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. 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The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032751", "l": "positive regulation of interleukin-27 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-27 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048473", "l": "D-methionine transport", "d": ["The directed movement of D-methionine into, out of, within, or between cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098923", "l": "retrograde trans-synaptic signaling by soluble gas", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:1901873", "l": "regulation of post-translational protein modification", "d": ["Any process that modulates the frequency, rate or extent of post-translational protein modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.898660913853604", "identifiers": [{"i": "GO:0019318", "l": "hexose metabolic process", "d": ["The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903091", "l": "pyridoxamine transmembrane transport", "d": ["The process in which pyridoxamine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014880", "l": "regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036146", "l": "cellular response to mycotoxin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900000", "l": "regulation of anthocyanin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of anthocyanin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070329", "l": "tRNA seleno-modification", "d": ["The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045600", "l": "positive regulation of fat cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of adipocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075296", "l": "positive regulation of ascospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.381710255175513", "identifiers": [{"i": "GO:0051656", "l": "establishment of organelle localization", "d": ["The directed movement of an organelle to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905001", "l": "negative regulation of membrane repolarization during atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007250", "l": "activation of NF-kappaB-inducing kinase activity", "d": ["The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032262", "l": "pyrimidine nucleotide salvage", "d": ["Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905170", "l": "negative regulation of protein localization to phagocytic vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150008", "l": "bulk synaptic vesicle endocytosis", "d": ["Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901109", "l": "granaticin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of granaticin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035677", "l": "posterior lateral line neuromast hair cell development", "d": ["The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072476", "l": "response to mitotic spindle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007386", "l": "compartment pattern specification", "d": ["The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035674", "l": "tricarboxylic acid transmembrane transport", "d": ["The process in which a tricarboxylic acid is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097534", "l": "lymphoid lineage cell migration", "d": ["The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051725", "l": "protein de-ADP-ribosylation", "d": ["The process of removing one or more ADP-ribose residues from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075138", "l": "response to host oxygen tension environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048082", "l": "regulation of adult chitin-containing cuticle pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003119", "l": "regulation of vasoconstriction by neuronal epinephrine", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904824", "l": "anaphase-promoting complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044865", "l": "negative regulation by virus of host cell division", "d": ["Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0110020", "l": "regulation of actomyosin structure organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032792", "l": "negative regulation of CREB transcription factor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.416800564412434", "identifiers": [{"i": "GO:0014051", "l": "gamma-aminobutyric acid secretion", "d": ["The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046080", "l": "dUTP metabolic process", "d": ["The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0061387", "l": "regulation of extent of cell growth", "d": ["Any process that modulates the extent of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905855", "l": "positive regulation of heparan sulfate binding", "d": ["Any process that activates or increases the frequency, rate or extent of heparan sulfate binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903147", "l": "negative regulation of autophagy of mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905932", "l": "positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900649", "l": "regulation of dehydroaustinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007352", "l": "zygotic specification of dorsal/ventral axis", "d": ["The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000116", "l": "regulation of cysteine-type endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035881", "l": "amacrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0018874", "l": "benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0031919", "l": "vitamin B6 transport", "d": ["The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902392", "l": "regulation of exodeoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097743", "l": "de novo centriole assembly via blepharoplast", "d": ["A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0043650", "l": "dicarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902006", "l": "negative regulation of proline biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034197", "l": "triglyceride transport", "d": ["The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.576180114155946", "identifiers": [{"i": "GO:0090087", "l": "regulation of peptide transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903228", "l": "xanthosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xanthosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035480", "l": "regulation of Notch signaling pathway involved in heart induction", "d": ["Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005995", "l": "melibiose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097067", "l": "cellular response to thyroid hormone stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000676", "l": "positive regulation of type B pancreatic cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904932", "l": "negative regulation of cartilage condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0006839", "l": "mitochondrial transport", "d": ["Transport of substances into, out of or within a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901148", "l": "gene expression involved in extracellular matrix organization", "d": ["Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071358", "l": "cellular response to type III interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045903", "l": "positive regulation of translational fidelity", "d": ["Any process that increases the ability of the translational apparatus to interpret the genetic code."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150019", "l": "basal dendrite morphogenesis", "d": ["The process in which the anatomical structures of a basal dendrite are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001240", "l": "negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030185", "l": "nitric oxide transport", "d": ["The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021860", "l": "pyramidal neuron development", "d": ["The progression of a pyramidal neuron from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030655", "l": "beta-lactam antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902584", "l": "positive regulation of response to water deprivation", "d": ["Any process that activates or increases the frequency, rate or extent of response to water deprivation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140516", "l": "mitotic nuclear pore complex disassembly", "d": ["The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990947", "l": "exit from meiosis", "d": ["Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900075", "l": "positive regulation of neuromuscular synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903884", "l": "regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000784", "l": "positive regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009454", "l": "aerotaxis", "d": ["The directed movement of a motile cell or organism in response to environmental oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905931", "l": "negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030709", "l": "border follicle cell delamination", "d": ["The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006424", "l": "glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072720", "l": "response to dithiothreitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060842", "l": "arterial endothelial cell differentiation", "d": ["The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075288", "l": "negative regulation of sporangiospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003309", "l": "type B pancreatic cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021960", "l": "anterior commissure morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0021593", "l": "rhombomere morphogenesis", "d": ["The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.608587053501218", "identifiers": [{"i": "GO:0015980", "l": "energy derivation by oxidation of organic compounds", "d": ["The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000376", "l": "positive regulation of oxygen metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of oxygen metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045832", "l": "positive regulation of light-activated channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of light-activated channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018174", "l": "protein-heme P460 linkage", "d": ["The linkage of protein to heme P460."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051590", "l": "positive regulation of neurotransmitter transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904561", "l": "cellular response to diphenidol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046126", "l": "pyrimidine deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0061437", "l": "renal system vasculature development", "d": ["The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035260", "l": "internal genitalia morphogenesis", "d": ["The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021762", "l": "substantia nigra development", "d": ["The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031887", "l": "lipid droplet transport along microtubule", "d": ["The directed movement of a lipid droplet along a microtubule, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031550", "l": "positive regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072685", "l": "Mre11 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071728", "l": "beak development", "d": ["The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010304", "l": "PSII associated light-harvesting complex II catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006515", "l": "protein quality control for misfolded or incompletely synthesized proteins", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099134", "l": "chimeric sorocarp development", "d": ["Development of a sorocarp formed by aggregation of cells with different genotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0099054", "l": "presynapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.670000558372379", "identifiers": [{"i": "GO:0042113", "l": "B cell activation", "d": ["The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140049", "l": "regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018076", "l": "N-terminal peptidyl-lysine acetylation", "d": ["The acetylation of the N-terminal lysine of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060996", "l": "dendritic spine development", "d": ["The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061009", "l": "common bile duct development", "d": ["The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051026", "l": "chiasma assembly", "d": ["The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052390", "l": "induction by symbiont of host innate immune response", "d": ["The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001989", "l": "positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060569", "l": "positive regulation of peptide hormone processing", "d": ["Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902230", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070638", "l": "pyridine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904395", "l": "positive regulation of skeletal muscle acetylcholine-gated channel clustering", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904947", "l": "folate import into mitochondrion", "d": ["The process in which folic acid is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901054", "l": "sarcosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sarcosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031339", "l": "negative regulation of vesicle fusion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903469", "l": "removal of RNA primer involved in mitotic DNA replication", "d": ["Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046852", "l": "positive regulation of bone remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of bone remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051767", "l": "nitric-oxide synthase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140076", "l": "negative regulation of lipoprotein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901716", "l": "negative regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052083", "l": "suppression by symbiont of host cell-mediated immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046221", "l": "pyridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902894", "l": "negative regulation of miRNA transcription", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0006007", "l": "glucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072127", "l": "renal capsule development", "d": ["The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072706", "l": "response to sodium dodecyl sulfate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000950", "l": "positive regulation of xyloglucan metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010257", "l": "NADH dehydrogenase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046494", "l": "rhizobactin 1021 metabolic process", "d": ["The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990683", "l": "DNA double-strand break attachment to nuclear envelope", "d": ["A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002040", "l": "sprouting angiogenesis", "d": ["The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050689", "l": "negative regulation of defense response to virus by host", "d": ["Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060310", "l": "regulation of elastin catabolic process", "d": ["Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000761", "l": "positive regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0050848", "l": "regulation of calcium-mediated signaling", "d": ["Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097090", "l": "presynaptic membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900699", "l": "negative regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120176", "l": "positive regulation of torso signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the torso signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032788", "l": "saturated monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033530", "l": "raffinose metabolic process", "d": ["The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007161", "l": "calcium-independent cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010755", "l": "regulation of plasminogen activation", "d": ["Any process that modulates the rate, frequency or extent of plasminogen activation. 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This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904004", "l": "positive regulation of sebum secreting cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090032", "l": "negative regulation of steroid hormone biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009668", "l": "plastid membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070447", "l": "positive regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002601", "l": "regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032927", "l": "positive regulation of activin receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0090382", "l": "phagosome maturation", "d": ["A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903904", "l": "negative regulation of establishment of T cell polarity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016031", "l": "tRNA import into mitochondrion", "d": ["The process in which a tRNA is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042194", "l": "quinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904711", "l": "regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0040004", "l": "collagen and cuticulin-based cuticle attachment to epithelium", "d": ["Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060128", "l": "corticotropin hormone secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.457311365574192", "identifiers": [{"i": "GO:0009582", "l": "detection of abiotic stimulus", "d": ["The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002441", "l": "histamine secretion involved in inflammatory response", "d": ["The regulated release of histamine by a cell as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014064", "l": "positive regulation of serotonin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033020", "l": "cyclopentanol metabolic process", "d": ["The chemical reactions and pathways involving cyclopentanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007387", "l": "anterior compartment pattern formation", "d": ["The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904698", "l": "negative regulation of acinar cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045487", "l": "gibberellin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0006094", "l": "gluconeogenesis", "d": ["The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.849844446926966", "identifiers": [{"i": "GO:0007155", "l": "cell adhesion", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1900785", "l": "naphtho-gamma-pyrone metabolic process", "d": ["The chemical reactions and pathways involving naphtho-gamma-pyrone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000752", "l": "regulation of glucosylceramide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043311", "l": "positive regulation of eosinophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.227705824148586", "identifiers": [{"i": "GO:1903530", "l": "regulation of secretion by cell", "d": ["Any process that modulates the frequency, rate or extent of secretion by cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051542", "l": "elastin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904918", "l": "transmembrane L-histidine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990461", "l": "detoxification of iron ion", "d": ["Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902418", "l": "(+)-abscisic acid D-glucopyranosyl ester transmembrane transport", "d": ["The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902283", "l": "negative regulation of primary amine oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904507", "l": "positive regulation of telomere maintenance in response to DNA damage", "d": ["Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061243", "l": "mesonephric renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014806", "l": "smooth muscle hyperplasia", "d": ["A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072759", "l": "cellular response to topoisomerase inhibitor", "d": ["Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990626", "l": "mitochondrial outer membrane fusion", "d": ["The membrane organization process that joins two mitochondrial outer membranes to form a single membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032250", "l": "negative regulation of adenosine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905322", "l": "positive regulation of mesenchymal stem cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060168", "l": "positive regulation of adenosine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000709", "l": "meiotic joint molecule formation", "d": ["The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060510", "l": "type II pneumocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0036503", "l": "ERAD pathway", "d": ["The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071909", "l": "determination of stomach left/right asymmetry", "d": ["Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045066", "l": "regulatory T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000620", "l": "positive regulation of histone H4-K16 acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098004", "l": "virus tail fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075255", "l": "teliospore formation", "d": ["The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001099", "l": "maltotetraose transport", "d": ["The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902766", "l": "skeletal muscle satellite cell migration", "d": ["The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019252", "l": "starch biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009726", "l": "detection of endogenous stimulus", "d": ["The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035330", "l": "regulation of hippo signaling", "d": ["Any process that modulates the frequency, rate or extent of hippo signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009102", "l": "biotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015825", "l": "L-serine transport", "d": ["The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990545", "l": "mitochondrial thiamine pyrophosphate transmembrane transport", "d": ["The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090667", "l": "cell chemotaxis to vascular endothelial growth factor", "d": ["The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF)."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.236426385580998", "identifiers": [{"i": "GO:0006887", "l": "exocytosis", "d": ["A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000781", "l": "positive regulation of double-strand break repair", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903071", "l": "positive regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010668", "l": "ectodermal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010706", "l": "ganglioside biosynthetic process via lactosylceramide", "d": ["The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060648", "l": "mammary gland bud morphogenesis", "d": ["The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061356", "l": "regulation of Wnt protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048647", "l": "polyphenic determination", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071354", "l": "cellular response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902634", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060527", "l": "prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis", "d": ["The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900447", "l": "regulation of cell morphogenesis involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000710", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002636", "l": "positive regulation of germinal center formation", "d": ["Any process that activates or increases the frequency, rate, or extent of germinal center formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141066", "l": "disruption of host extracellular matrix", "d": ["The chemical reactions and pathways performed by an symbiont resulting in the breakdown of the extracellular matrix of its host."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062099", "l": "negative regulation of programmed necrotic cell death", "d": ["Any process that decreases the frequency, rate or extent of programmed necrotic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018171", "l": "peptidyl-cysteine oxidation", "d": ["The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061083", "l": "regulation of protein refolding", "d": ["Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034126", "l": "positive regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046839", "l": "phospholipid dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032960", "l": "regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006167", "l": "AMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010569", "l": "regulation of double-strand break repair via homologous recombination", "d": ["Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0006979", "l": "response to oxidative stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902216", "l": "positive regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044751", "l": "cellular response to human chorionic gonadotropin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0043666", "l": "regulation of phosphoprotein phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904926", "l": "response to palmitoleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035437", "l": "maintenance of protein localization in endoplasmic reticulum", "d": ["Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006256", "l": "UDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900725", "l": "osmoregulated periplasmic glucan metabolic process", "d": ["The chemical reactions and pathways involving osmoregulated periplasmic glucan."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0008154", "l": "actin polymerization or depolymerization", "d": ["Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035998", "l": "7,8-dihydroneopterin 3'-triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019630", "l": "quinate metabolic process", "d": ["The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035653", "l": "clathrin-coated vesicle cargo loading, AP-1-mediated", "d": ["Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044494", "l": "envenomation resulting in positive regulation of voltage-gated sodium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035432", "l": "positive regulation of gluconate transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.453469727007125", "identifiers": [{"i": "GO:0061534", "l": "gamma-aminobutyric acid secretion, neurotransmission", "d": ["The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120189", "l": "positive regulation of bile acid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0009658", "l": "chloroplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045616", "l": "regulation of keratinocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000493", "l": "negative regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.677603159285916", "identifiers": [{"i": "GO:0034470", "l": "ncRNA processing", "d": ["Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904391", "l": "response to ciliary neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048727", "l": "posterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034077", "l": "butanediol metabolic process", "d": ["The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0016445", "l": "somatic diversification of immunoglobulins", "d": ["The somatic process that results in the generation of sequence diversity of immunoglobulins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052707", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine", "d": ["The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045809", "l": "positive regulation of establishment of competence for transformation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000212", "l": "negative regulation of glutamate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001100", "l": "negative regulation of exit from mitosis", "d": ["Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000512", "l": "lncRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032570", "l": "response to progesterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030517", "l": "negative regulation of axon extension", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072239", "l": "metanephric glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000171", "l": "negative regulation of dendrite development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901208", "l": "negative regulation of heart looping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heart looping."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046682", "l": "response to cyclodiene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042196", "l": "chlorinated hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903528", "l": "regulation of dCDP biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dCDP biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0007019", "l": "microtubule depolymerization", "d": ["The removal of tubulin heterodimers from one or both ends of a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002308", "l": "CD8-positive, alpha-beta cytotoxic T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021686", "l": "cerebellar granular layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140023", "l": "tRNA adenosine deamination to inosine", "d": ["The removal of an amine group from an adenosine to produce inosine within a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905194", "l": "positive regulation of chloroplast fission", "d": ["Any process that activates or increases the frequency, rate or extent of chloroplast fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071413", "l": "cellular response to hydroxyisoflavone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071385", "l": "cellular response to glucocorticoid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006315", "l": "homing of group II introns", "d": ["Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072565", "l": "endothelial microparticle formation", "d": ["The cellular component organization process in which microparticles bud off from an endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021554", "l": "optic nerve development", "d": ["The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.24517279685756", "identifiers": [{"i": "GO:0019230", "l": "proprioception", "d": ["The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048208", "l": "COPII vesicle coating", "d": ["The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000034", "l": "regulation of seed maturation", "d": ["Any process that modulates the frequency, rate or extent of seed maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010041", "l": "response to iron(III) ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "29.515561398893677", "identifiers": [{"i": "GO:0009790", "l": "embryo development", "d": ["The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010908", "l": "regulation of heparan sulfate proteoglycan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0046889", "l": "positive regulation of lipid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901233", "l": "negative regulation of convergent extension involved in axis elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902205", "l": "regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033540", "l": "fatty acid beta-oxidation using acyl-CoA oxidase", "d": ["A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002840", "l": "regulation of T cell mediated immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035147", "l": "branch fusion, open tracheal system", "d": ["Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006061", "l": "sorbitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003347", "l": "epicardial cell to mesenchymal cell transition", "d": ["A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036494", "l": "positive regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110031", "l": "negative regulation of G2/MI transition of meiotic cell cycle", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.937454763326897", "identifiers": [{"i": "GO:0046631", "l": "alpha-beta T cell activation", "d": ["The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018870", "l": "anaerobic 2-aminobenzoate metabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071707", "l": "immunoglobulin heavy chain V-D-J recombination", "d": ["The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0006949", "l": "syncytium formation", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055107", "l": "Golgi to secretory granule transport", "d": ["The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033398", "l": "zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015012", "l": "heparan sulfate proteoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0018149", "l": "peptide cross-linking", "d": ["The formation of a covalent cross-link between or within protein chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080178", "l": "5-carbamoylmethyl uridine residue modification", "d": ["The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001986", "l": "negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure", "d": ["Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071519", "l": "actomyosin contractile ring actin filament bundle assembly", "d": ["A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141013", "l": "purine nucleotide import into lysosome", "d": ["The directed import of purine nucleotide from the cytosol, across the lysosomal membrane, into the lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905489", "l": "regulation of sensory neuron axon guidance", "d": ["Any process that modulates the frequency, rate or extent of sensory neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006041", "l": "glucosamine metabolic process", "d": ["The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033272", "l": "myo-inositol hexakisphosphate transport", "d": ["The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904883", "l": "negative regulation of telomerase catalytic core complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905630", "l": "response to glyceraldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010449", "l": "root meristem growth", "d": ["The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071659", "l": "negative regulation of IP-10 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035078", "l": "induction of programmed cell death by ecdysone", "d": ["Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046851", "l": "negative regulation of bone remodeling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120290", "l": "stalled replication fork localization to nuclear periphery", "d": ["A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002259", "l": "endothelial cell activation within high endothelial venule involved in immune response", "d": ["A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0061240", "l": "mesonephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060095", "l": "zinc potentiation of synaptic transmission, glycinergic", "d": ["Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046495", "l": "nicotinamide riboside metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010822", "l": "positive regulation of mitochondrion organization", "d": ["Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021740", "l": "principal sensory nucleus of trigeminal nerve development", "d": ["The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010983", "l": "positive regulation of high-density lipoprotein particle clearance", "d": ["Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905702", "l": "regulation of inhibitory synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of inhibitory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901864", "l": "capsorubin metabolic process", "d": ["The chemical reactions and pathways involving capsorubin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900438", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034095", "l": "negative regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034175", "l": "regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072334", "l": "UDP-galactose transmembrane transport", "d": ["The process in which UDP-galactose is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036496", "l": "regulation of translational initiation by eIF2 alpha dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061279", "l": "epithelial cell migration involved in mesonephric distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021817", "l": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "d": ["The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048690", "l": "regulation of axon extension involved in regeneration", "d": ["Any process that modulates the frequency, rate or extent of axon extension involved in regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035679", "l": "anterior lateral line neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0043324", "l": "pigment metabolic process involved in developmental pigmentation", "d": ["The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015905", "l": "bicyclomycin transmembrane transport", "d": ["The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. 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The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018227", "l": "peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0055017", "l": "cardiac muscle tissue growth", "d": ["The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070715", "l": "sodium-dependent organic cation transport", "d": ["The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014846", "l": "esophagus smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. 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The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1901159", "l": "xylulose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110121", "l": "gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008057", "l": "eye pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045455", "l": "ecdysteroid metabolic process", "d": ["The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0032387", "l": "negative regulation of intracellular transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0090030", "l": "regulation of steroid hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021796", "l": "cerebral cortex regionalization", "d": ["The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001210", "l": "regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090687", "l": "activation of meiosis I spindle assembly checkpoint", "d": ["Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901332", "l": "negative regulation of lateral root development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072488", "l": "ammonium transmembrane transport", "d": ["The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060245", "l": "detection of cell density", "d": ["The series of events in which information about the density of cells in a population is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0046485", "l": "ether lipid metabolic process", "d": ["The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045091", "l": "regulation of single stranded viral RNA replication via double stranded DNA intermediate", "d": ["Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072712", "l": "response to thiabendazole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046534", "l": "positive regulation of photoreceptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903384", "l": "negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000083", "l": "negative regulation of L-ascorbic acid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071239", "l": "cellular response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046369", "l": "galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904303", "l": "positive regulation of maternal process involved in parturition", "d": ["Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.55589269399384", "identifiers": [{"i": "GO:0043576", "l": "regulation of respiratory gaseous exchange", "d": ["Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150195", "l": "transport across blood-cerebrospinal fluid barrier", "d": ["The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043087", "l": "regulation of GTPase activity", "d": ["Any process that modulates the rate of GTP hydrolysis by a GTPase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070930", "l": "trans-translation-dependent protein tagging", "d": ["A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033659", "l": "disruption by symbiont of host mitochondrion", "d": ["The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032443", "l": "regulation of ergosterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098905", "l": "regulation of bundle of His cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010500", "l": "transmitting tissue development", "d": ["The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075267", "l": "aecium development", "d": ["The process in which a cup-like structure containing chains of aeciospores is formed. 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Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043378", "l": "positive regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072429", "l": "response to intra-S DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0045229", "l": "external encapsulating structure organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090670", "l": "RNA localization to Cajal body", "d": ["A process in which an RNA is transported to, or maintained in, a Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900441", "l": "negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905780", "l": "regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060424", "l": "lung field specification", "d": ["The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0006633", "l": "fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032724", "l": "positive regulation of fractalkine production", "d": ["Any process that activates or increases the frequency, rate, or extent of fractalkine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032048", "l": "cardiolipin metabolic process", "d": ["The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021623", "l": "oculomotor nerve formation", "d": ["The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106044", "l": "guanine deglycation", "d": ["The removal of a sugar or dicarbonyl from a glycated guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0035188", "l": "hatching", "d": ["The emergence of an immature organism from a protective structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0015705", "l": "iodide transport", "d": ["The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061093", "l": "negative regulation of phospholipid translocation", "d": ["Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902489", "l": "hepatoblast apoptotic process", "d": ["Any apoptotic process in a hepatoblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000393", "l": "spliceosomal conformational changes to generate catalytic conformation", "d": ["Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003301", "l": "physiological cardiac muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901025", "l": "ripoptosome assembly involved in extrinsic apoptotic signaling pathway", "d": ["The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0051223", "l": "regulation of protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033399", "l": "cis-zeatin metabolic process", "d": ["The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044071", "l": "perturbation of host cell cycle progression", "d": ["A process in which a symbiont interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035027", "l": "leading edge cell fate commitment", "d": ["The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904312", "l": "cellular response to gold(3+)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048664", "l": "neuron fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.862176725069006", "identifiers": [{"i": "GO:0050794", "l": "regulation of cellular process", "d": ["Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140845", "l": "regulation of promoter clearance from RNA polymerase II promoter", "d": ["A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.203304431560539", "identifiers": [{"i": "GO:0120035", "l": "regulation of plasma membrane bounded cell projection organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0075016", "l": "appressorium formation", "d": ["The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "15.43509208078026", "identifiers": [{"i": "GO:0008150", "l": "biological_process", "d": ["A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905362", "l": "negative regulation of endosomal vesicle fusion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031666", "l": "positive regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071315", "l": "cellular response to morphine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901865", "l": "capsorubin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of capsorubin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904994", "l": "regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990668", "l": "vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018879", "l": "biphenyl metabolic process", "d": ["The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.885542599809028", "identifiers": [{"i": "GO:0002524", "l": "hypersensitivity", "d": ["An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034157", "l": "positive regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140459", "l": "response to Gram-positive bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035071", "l": "salivary gland cell autophagic cell death", "d": ["The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042213", "l": "m-cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000596", "l": "negative regulation of optic nerve formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0023021", "l": "termination of signal transduction", "d": ["The signaling process in which signal transduction is brought to an end rather than being reversibly modulated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902798", "l": "positive regulation of snoRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of snoRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061352", "l": "cell chemotaxis involved in Malpighian tubule morphogenesis", "d": ["The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0050803", "l": "regulation of synapse structure or activity", "d": ["Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030714", "l": "anterior/posterior axis specification, follicular epithelium", "d": ["Polarization of the follicle cells of an insect ovary along the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034758", "l": "positive regulation of iron ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0050671", "l": "positive regulation of lymphocyte proliferation", "d": ["Any process that activates or increases the rate or extent of lymphocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904882", "l": "regulation of telomerase catalytic core complex assembly", "d": ["Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.632502155555215", "identifiers": [{"i": "GO:1901564", "l": "organonitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving organonitrogen compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007277", "l": "pole cell development", "d": ["The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002225", "l": "positive regulation of antimicrobial peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071377", "l": "cellular response to glucagon stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0031623", "l": "receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061855", "l": "negative regulation of neuroblast migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032615", "l": "interleukin-12 production", "d": ["The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051900", "l": "regulation of mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071243", "l": "cellular response to arsenic-containing substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.947183007037978", "identifiers": [{"i": "GO:0015695", "l": "organic cation transport", "d": ["The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007378", "l": "amnioserosa formation", "d": ["Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006544", "l": "glycine metabolic process", "d": ["The chemical reactions and pathways involving glycine, aminoethanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045764", "l": "positive regulation of amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904413", "l": "negative regulation of cardiac ventricle development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006701", "l": "progesterone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006828", "l": "manganese ion transport", "d": ["The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032148", "l": "activation of protein kinase B activity", "d": ["Any process that initiates the activity of the inactive enzyme protein kinase B."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034129", "l": "positive regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903377", "l": "negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019092", "l": "mitochondrial srRNA export from mitochondrion", "d": ["The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904846", "l": "negative regulation of establishment of bipolar cell polarity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052696", "l": "flavonoid glucuronidation", "d": ["The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045201", "l": "maintenance of neuroblast polarity", "d": ["The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904220", "l": "regulation of serine C-palmitoyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000988", "l": "regulation of hemicellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of hemicellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901870", "l": "ecgonone methyl ester metabolic process", "d": ["The chemical reactions and pathways involving ecgonone methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009449", "l": "gamma-aminobutyric acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043645", "l": "cephalosporin metabolic process", "d": ["The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009455", "l": "redox taxis", "d": ["The directed movement of a motile cell or organism in response to redox potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0032535", "l": "regulation of cellular component size", "d": ["A process that modulates the size of a cellular component."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0043549", "l": "regulation of kinase activity", "d": ["Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905040", "l": "otic placode development", "d": ["The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0006026", "l": "aminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000877", "l": "negative regulation of oligopeptide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0051318", "l": "G1 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044552", "l": "vasodilation in another organism", "d": ["A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904715", "l": "negative regulation of chaperone-mediated autophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900010", "l": "regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0061157", "l": "mRNA destabilization", "d": ["Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0045936", "l": "negative regulation of phosphate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061225", "l": "mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071652", "l": "regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071584", "l": "negative regulation of zinc ion transmembrane import", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090140", "l": "regulation of mitochondrial fission", "d": ["Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904682", "l": "cellular response to 3-methylcholanthrene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015871", "l": "choline transport", "d": ["The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045204", "l": "MAPK export from nucleus", "d": ["The directed movement of a MAP kinase from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0030416", "l": "methylamine metabolic process", "d": ["The chemical reactions and pathways involving methylamine (CH3NH2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019413", "l": "acetate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042669", "l": "regulation of inner ear auditory receptor cell fate specification", "d": ["Any process that mediates the specification of a cell into an auditory hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072282", "l": "metanephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048809", "l": "analia morphogenesis", "d": ["The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072256", "l": "metanephric glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046444", "l": "FMN metabolic process", "d": ["The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042696", "l": "menarche", "d": ["The beginning of the menstrual cycle; the first menstrual cycle in an individual."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000031", "l": "regulation of salicylic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003005", "l": "follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage", "d": ["The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061541", "l": "rhabdomere morphogenesis", "d": ["The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097327", "l": "response to antineoplastic agent", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060936", "l": "cardiac fibroblast cell development", "d": ["The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002071", "l": "glandular epithelial cell maturation", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043406", "l": "positive regulation of MAP kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of MAP kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031284", "l": "positive regulation of guanylate cyclase activity", "d": ["Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901947", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905321", "l": "negative regulation of mesenchymal stem cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035973", "l": "aggrephagy", "d": ["Selective degradation of protein aggregates by macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070145", "l": "mitochondrial asparaginyl-tRNA aminoacylation", "d": ["The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075228", "l": "positive regulation of encysted zoospore germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044694", "l": "pore-mediated entry of viral genome into host cell", "d": ["Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051515", "l": "positive regulation of monopolar cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032264", "l": "IMP salvage", "d": ["Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071247", "l": "cellular response to chromate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035896", "l": "positive regulation of mast cell degranulation in another organism", "d": ["Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904863", "l": "regulation of beta-catenin-TCF complex assembly", "d": ["Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905623", "l": "positive regulation of leaf development", "d": ["Any process that activates or increases the frequency, rate or extent of leaf development."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.798293818031638", "identifiers": [{"i": "GO:0070727", "l": "cellular macromolecule localization", "d": ["Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903619", "l": "negative regulation of transdifferentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0048754", "l": "branching morphogenesis of an epithelial tube", "d": ["The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034729", "l": "histone H3-K79 methylation", "d": ["The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045313", "l": "rhabdomere membrane biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071979", "l": "cytoskeleton-mediated cell swimming", "d": ["Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061154", "l": "endothelial tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071030", "l": "nuclear mRNA surveillance of spliceosomal pre-mRNA splicing", "d": ["The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070560", "l": "protein secretion by platelet", "d": ["The regulated release of proteins by a platelet or group of platelets."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051177", "l": "meiotic sister chromatid cohesion", "d": ["The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003100", "l": "regulation of systemic arterial blood pressure by endothelin", "d": ["The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098037", "l": "viral DNA genome packaging, 5' extended cos packaging", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904600", "l": "mating projection actin fusion focus assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904648", "l": "cellular response to rotenone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990274", "l": "mitotic actomyosin contractile ring disassembly", "d": ["Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904604", "l": "negative regulation of advanced glycation end-product receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070846", "l": "Hsp90 deacetylation", "d": ["The modification of an Hsp90 protein by removal of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071316", "l": "cellular response to nicotine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060623", "l": "regulation of chromosome condensation", "d": ["Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042363", "l": "fat-soluble vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052005", "l": "suppression by symbiont of host ethylene-mediated defense response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.753431535235705", "identifiers": [{"i": "GO:0044270", "l": "cellular nitrogen compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902374", "l": "regulation of rRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of rRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000553", "l": "positive regulation of T-helper 2 cell cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905293", "l": "negative regulation of neural crest cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019708", "l": "peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine", "d": ["The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032275", "l": "luteinizing hormone secretion", "d": ["The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905340", "l": "regulation of protein localization to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of protein localization to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010949", "l": "negative regulation of intestinal phytosterol absorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050893", "l": "sensory processing", "d": ["Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009659", "l": "leucoplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046378", "l": "enterobacterial common antigen metabolic process", "d": ["The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:2001235", "l": "positive regulation of apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035600", "l": "tRNA methylthiolation", "d": ["The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.56322629516173", "identifiers": [{"i": "GO:0006807", "l": "nitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000495", "l": "box H/ACA RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a box H/ACA RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009789", "l": "positive regulation of abscisic acid-activated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904325", "l": "positive regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000510", "l": "positive regulation of dendritic cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.618744678332945", "identifiers": [{"i": "GO:0090257", "l": "regulation of muscle system process", "d": ["Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0006833", "l": "water transport", "d": ["The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060979", "l": "vasculogenesis involved in coronary vascular morphogenesis", "d": ["The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052032", "l": "perturbation by symbiont of host inflammatory response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007341", "l": "penetration of zona pellucida", "d": ["The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150174", "l": "negative regulation of phosphatidylcholine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002916", "l": "positive regulation of central B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002233", "l": "leukocyte chemotaxis involved in immune response", "d": ["The movement of an immune cell in response to an external stimulus a part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060250", "l": "germ-line stem-cell niche homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019267", "l": "asparagine biosynthetic process from cysteine", "d": ["The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060613", "l": "fat pad development", "d": ["The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051594", "l": "detection of glucose", "d": ["The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904697", "l": "regulation of acinar cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of acinar cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090251", "l": "protein localization involved in establishment of planar polarity", "d": ["Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990926", "l": "short-term synaptic potentiation", "d": ["The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045570", "l": "regulation of imaginal disc growth", "d": ["Any process that modulates the frequency, rate or extent of the growth of the imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042740", "l": "exogenous antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039516", "l": "modulation by virus of host catalytic activity", "d": ["The process in which a virus effects a change in host enzyme activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070844", "l": "polyubiquitinated protein transport", "d": ["The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0034367", "l": "protein-containing complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0048546", "l": "digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the digestive tract are generated and organized. 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Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071255", "l": "Cvt vesicle assembly", "d": ["A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0046951", "l": "ketone body biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031269", "l": "pseudopodium assembly", "d": ["The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0072378", "l": "blood coagulation, fibrin clot formation", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904022", "l": "positive regulation of G protein-coupled receptor internalization", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.85341545293393", "identifiers": [{"i": "GO:0002285", "l": "lymphocyte activation involved in immune response", "d": ["A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903786", "l": "regulation of glutathione biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of glutathione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021861", "l": "forebrain radial glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072751", "l": "cellular response to L-thialysine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034443", "l": "negative regulation of lipoprotein oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902939", "l": "negative regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000814", "l": "positive regulation of barbed-end actin filament capping", "d": ["Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006676", "l": "mannosyl diphosphorylinositol ceramide metabolic process", "d": ["The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.181576135344244", "identifiers": [{"i": "GO:0030155", "l": "regulation of cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090363", "l": "regulation of proteasome core complex assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019653", "l": "anaerobic purine nucleobase catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.095679833930788", "identifiers": [{"i": "GO:0090068", "l": "positive regulation of cell cycle process", "d": ["Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033353", "l": "S-adenosylmethionine cycle", "d": ["A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042985", "l": "negative regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048312", "l": "intracellular distribution of mitochondria", "d": ["Any process that establishes the spatial arrangement of mitochondria within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031394", "l": "positive regulation of prostaglandin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044858", "l": "plasma membrane raft polarization", "d": ["The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030070", "l": "insulin processing", "d": ["The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905134", "l": "positive regulation of meiotic chromosome separation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900081", "l": "regulation of arginine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of arginine catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060988", "l": "lipid tube assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0019519", "l": "pentitol metabolic process", "d": ["The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0000460", "l": "maturation of 5.8S rRNA", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034670", "l": "chemotaxis to arachidonic acid", "d": ["The directed movement of a motile cell or organism in response to the presence of arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009052", "l": "pentose-phosphate shunt, non-oxidative branch", "d": ["The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106120", "l": "positive regulation of sterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009907", "l": "response to photoperiod, red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090370", "l": "negative regulation of cholesterol efflux", "d": ["Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006531", "l": "aspartate metabolic process", "d": ["The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042732", "l": "D-xylose metabolic process", "d": ["The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048499", "l": "synaptic vesicle membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900693", "l": "negative regulation of (+)-kotanin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902916", "l": "positive regulation of protein polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048275", "l": "N-terminal peptidyl-arginine acetylation", "d": ["The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031537", "l": "regulation of anthocyanin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090274", "l": "positive regulation of somatostatin secretion", "d": ["Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990185", "l": "regulation of lymphatic vascular permeability", "d": ["Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904871", "l": "positive regulation of protein localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140706", "l": "protein-containing complex localization to centriolar satellite", "d": ["A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048023", "l": "positive regulation of melanin biosynthetic process", "d": ["Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990781", "l": "response to immobilization stress combined with electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905789", "l": "positive regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901773", "l": "lincomycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lincomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990895", "l": "regulation of protein localization to cell cortex of cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090038", "l": "negative regulation of protein kinase C signaling", "d": ["Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090522", "l": "vesicle tethering involved in exocytosis", "d": ["The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902172", "l": "regulation of keratinocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0080147", "l": "root hair cell development", "d": ["The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001291", "l": "codeine metabolic process", "d": ["The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001893", "l": "maternal placenta development", "d": ["Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0031343", "l": "positive regulation of cell killing", "d": ["Any process that activates or increases the frequency, rate or extent of cell killing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009239", "l": "enterobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035562", "l": "negative regulation of chromatin binding", "d": ["Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036070", "l": "light-independent bacteriochlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043482", "l": "cellular pigment accumulation", "d": ["The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061188", "l": "negative regulation of rDNA heterochromatin formation", "d": ["Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006465", "l": "signal peptide processing", "d": ["The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019583", "l": "galactonate metabolic process", "d": ["The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035970", "l": "peptidyl-threonine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050765", "l": "negative regulation of phagocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061212", "l": "mesonephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035912", "l": "dorsal aorta morphogenesis", "d": ["The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904560", "l": "response to diphenidol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901460", "l": "regulation of response to formic acid", "d": ["Any process that modulates the frequency, rate or extent of response to formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0051209", "l": "release of sequestered calcium ion into cytosol", "d": ["The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0046174", "l": "polyol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000238", "l": "zygotene", "d": ["The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000652", "l": "regulation of secondary cell wall biogenesis", "d": ["Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021911", "l": "retinoic acid metabolic process in spinal cord anterior-posterior patterning", "d": ["The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033349", "l": "apiose metabolic process", "d": ["The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061284", "l": "specification of mesonephric proximal tubule identity", "d": ["The process in which the proximal tubule of the mesonephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106128", "l": "negative regulation of store-operated calcium entry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070445", "l": "regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060713", "l": "labyrinthine layer morphogenesis", "d": ["The process in which the labyrinthine layer of the placenta is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902009", "l": "positive regulation of toxin transport", "d": ["Any process that activates or increases the frequency, rate or extent of toxin transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097267", "l": "omega-hydroxylase P450 pathway", "d": ["The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901446", "l": "negative regulation of response to propan-1-ol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0007422", "l": "peripheral nervous system development", "d": ["The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903601", "l": "thermospermine metabolic process", "d": ["The chemical reactions and pathways involving thermospermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061111", "l": "epithelial-mesenchymal cell signaling involved in lung development", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097328", "l": "response to carboplatin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000454", "l": "snoRNA guided rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015628", "l": "protein secretion by the type II secretion system", "d": ["The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048209", "l": "regulation of vesicle targeting, to, from or within Golgi", "d": ["Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035928", "l": "rRNA import into mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019645", "l": "anaerobic electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904213", "l": "negative regulation of iodide transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052042", "l": "induction by symbiont of host programmed cell death", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900594", "l": "(+)-kotanin metabolic process", "d": ["The chemical reactions and pathways involving (+)-kotanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0120253", "l": "hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060431", "l": "primary lung bud formation", "d": ["The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120320", "l": "lateral pseudopodium retraction", "d": ["The myosin-based contraction and retraction of a lateral pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000098", "l": "negative regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032254", "l": "establishment of secretory granule localization", "d": ["The directed movement of a secretory granule to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046163", "l": "heme C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048630", "l": "skeletal muscle tissue growth", "d": ["The increase in size or mass of a skeletal muscle. 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Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120047", "l": "positive regulation of protein localization to medial cortical node", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031038", "l": "myosin II filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902125", "l": "(+)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006398", "l": "mRNA 3'-end processing by stem-loop binding and cleavage", "d": ["Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904874", "l": "positive regulation of telomerase RNA localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033253", "l": "regulation of penicillinase activity", "d": ["Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0010921", "l": "regulation of phosphatase activity", "d": ["Any process that modulates the rate or frequency of phosphatase activity. 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of integrin activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048617", "l": "embryonic foregut morphogenesis", "d": ["The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045993", "l": "negative regulation of translational initiation by iron", "d": ["Any process involving iron that stops, prevents or reduces the rate of translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046123", "l": "purine deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060055", "l": "angiogenesis involved in wound healing", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.297762971210318", "identifiers": [{"i": "GO:0019220", "l": "regulation of phosphate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:1901659", "l": "glycosyl compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosyl compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045574", "l": "sterigmatocystin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901534", "l": "positive regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:1904063", "l": "negative regulation of cation transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098749", "l": "cerebellar neuron development", "d": ["The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900485", "l": "positive regulation of protein targeting to vacuolar membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032972", "l": "regulation of muscle filament sliding speed", "d": ["Any process that modulates the velocity of muscle filament sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044780", "l": "bacterial-type flagellum assembly", "d": ["The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0010962", "l": "regulation of glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900087", "l": "positive regulation of G1/S transition of mitotic cell cycle", "d": ["Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903857", "l": "negative regulation of cytokinin dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034447", "l": "very-low-density lipoprotein particle clearance", "d": ["The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001767", "l": "establishment of lymphocyte polarity", "d": ["The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071964", "l": "establishment of cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071908", "l": "determination of intestine left/right asymmetry", "d": ["Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019755", "l": "one-carbon compound transport", "d": ["The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032917", "l": "polyamine acetylation", "d": ["The modification of polyamines by addition of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043108", "l": "pilus retraction", "d": ["The process of withdrawing a pilus back into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1905331", "l": "negative regulation of morphogenesis of an epithelium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021743", "l": "hypoglossal nucleus development", "d": ["The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002148", "l": "hypochlorous acid metabolic process", "d": ["The chemical reactions and pathways involving hypochlorous acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051206", "l": "silicate metabolic process", "d": ["The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001810", "l": "regulation of type I hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0072109", "l": "glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002638", "l": "negative regulation of immunoglobulin production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000640", "l": "positive regulation of SREBP signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060690", "l": "epithelial cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015714", "l": "phosphoenolpyruvate transport", "d": ["The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070233", "l": "negative regulation of T cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048381", "l": "lateral mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002388", "l": "immune response in Peyer's patch", "d": ["Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009804", "l": "coumarin metabolic process", "d": ["The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001131", "l": "methane biosynthetic process from dimethyl sulfide", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901341", "l": "positive regulation of store-operated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033021", "l": "cyclopentanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclopentanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000457", "l": "positive regulation of T-helper 17 cell extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090673", "l": "endothelial cell-matrix adhesion", "d": ["The binding of an endothelial cell to the extracellular matrix via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062096", "l": "kinetochore disassembly", "d": ["The disaggregation of a kinetochore into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019471", "l": "4-hydroxyproline metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052159", "l": "perturbation of host induced systemic resistance", "d": ["A process in which an organism effects a change that affects the induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061161", "l": "positive regulation of establishment of bipolar cell polarity regulating cell shape", "d": ["Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033377", "l": "maintenance of protein location in T cell secretory granule", "d": ["A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019414", "l": "aerobic respiration, using sulfur or sulfate as electron donor", "d": ["An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.964982859529293", "identifiers": [{"i": "GO:0003012", "l": "muscle system process", "d": ["A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072754", "l": "cellular response to purvalanol A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0032410", "l": "negative regulation of transporter activity", "d": ["Any process that stops or reduces the activity of a transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061767", "l": "negative regulation of lung blood pressure", "d": ["The process that decreases the force with which blood travels through the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:1905770", "l": "regulation of mesodermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900786", "l": "naphtho-gamma-pyrone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046427", "l": "positive regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072688", "l": "SHREC complex localization", "d": ["Any process in which a SHREC complex is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.75272396535307", "identifiers": [{"i": "GO:0072088", "l": "nephron epithelium morphogenesis", "d": ["The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090517", "l": "L-lysine transmembrane import into vacuole", "d": ["The directed movement of L-lysine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0015748", "l": "organophosphate ester transport", "d": ["The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030209", "l": "dermatan sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902055", "l": "positive regulation of neosartoricin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032495", "l": "response to muramyl dipeptide", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110098", "l": "positive regulation of calcium import into the mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.094833137172827", "identifiers": [{"i": "GO:0001503", "l": "ossification", "d": ["The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140145", "l": "copper ion export from vacuole", "d": ["The directed movement of copper ions out of the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034446", "l": "substrate adhesion-dependent cell spreading", "d": ["The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900943", "l": "positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014866", "l": "skeletal myofibril assembly", "d": ["The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141071", "l": "symbiont-mediated activation of host MAPK signal transduction pathway", "d": ["A process in which a symbiont subverts a MAPK signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.709680529981043", "identifiers": [{"i": "GO:0044281", "l": "small molecule metabolic process", "d": ["The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030382", "l": "sperm mitochondrion organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070484", "l": "dehydro-D-arabinono-1,4-lactone metabolic process", "d": ["The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901835", "l": "positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070434", "l": "positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031111", "l": "negative regulation of microtubule polymerization or depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0002066", "l": "columnar/cuboidal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071600", "l": "otic vesicle morphogenesis", "d": ["The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060957", "l": "endocardial cell fate commitment", "d": ["The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. 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The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006964", "l": "positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048567", "l": "ectodermal digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002022", "l": "detection of dietary excess", "d": ["The neurological process in which the brain senses excessive caloric intake."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905235", "l": "response to quercetin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904046", "l": "negative regulation of vascular endothelial growth factor production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043375", "l": "CD8-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903318", "l": "negative regulation of protein maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0036294", "l": "cellular response to decreased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060406", "l": "positive regulation of penile erection", "d": ["Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905629", "l": "positive regulation of serotonin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010649", "l": "regulation of cell communication by electrical coupling", "d": ["Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098728", "l": "germline stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0031503", "l": "protein-containing complex localization", "d": ["A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000657", "l": "negative regulation of apolipoprotein binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0006555", "l": "methionine metabolic process", "d": ["The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0046661", "l": "male sex differentiation", "d": ["The establishment of the sex of a male organism by physical differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062225", "l": "negative regulation of somatic muscle development", "d": ["Any process that decreases the rate, frequency or extent of somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018026", "l": "peptidyl-lysine monomethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0031331", "l": "positive regulation of cellular catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019461", "l": "glutamine catabolic process to fumarate, using glutamate synthase (NADPH)", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035971", "l": "peptidyl-histidine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0072074", "l": "kidney mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0072678", "l": "T cell migration", "d": ["The movement of a T cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002203", "l": "proteolysis by cytosolic proteases associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0101018", "l": "negative regulation of mitotic DNA replication initiation from late origin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0048813", "l": "dendrite morphogenesis", "d": ["The process in which the anatomical structures of a dendrite are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904761", "l": "negative regulation of myofibroblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002650", "l": "negative regulation of tolerance induction to self antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019573", "l": "D-arabinose catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1990138", "l": "neuron projection extension", "d": ["Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099403", "l": "maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010946", "l": "regulation of meiotic joint molecule formation", "d": ["Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090381", "l": "regulation of heart induction", "d": ["Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.582294905512683", "identifiers": [{"i": "GO:0043170", "l": "macromolecule metabolic process", "d": ["The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017055", "l": "negative regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009193", "l": "pyrimidine ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902869", "l": "regulation of amacrine cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of amacrine cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097069", "l": "cellular response to thyroxine stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060434", "l": "bronchus morphogenesis", "d": ["The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902529", "l": "negative regulation of protein linear polyubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000750", "l": "negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015760", "l": "glucose-6-phosphate transport", "d": ["The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090358", "l": "positive regulation of tryptophan metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905603", "l": "regulation of blood-brain barrier permeability", "d": ["Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0042326", "l": "negative regulation of phosphorylation", "d": ["Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032382", "l": "positive regulation of intracellular sterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097093", "l": "polyacyltrehalose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904957", "l": "negative regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044565", "l": "dendritic cell proliferation", "d": ["The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905391", "l": "regulation of protein localization to cell division site involved in cell separation after cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051157", "l": "arabitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901733", "l": "quercetin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quercetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0042461", "l": "photoreceptor cell development", "d": ["Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.769355763942954", "identifiers": [{"i": "GO:0001843", "l": "neural tube closure", "d": ["The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033599", "l": "regulation of mammary gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044541", "l": "zymogen activation in another organism", "d": ["The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032020", "l": "ISG15-protein conjugation", "d": ["The covalent addition to a protein of ISG15, a ubiquitin-like protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0052803", "l": "imidazole-containing compound metabolic process", "d": ["The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0019693", "l": "ribose phosphate metabolic process", "d": ["The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044496", "l": "negative regulation of blood pressure in another organism", "d": ["A process by which one organism decreases the force with which blood travels through the circulatory system of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:2000404", "l": "regulation of T cell migration", "d": ["Any process that modulates the frequency, rate or extent of T cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0032602", "l": "chemokine production", "d": ["The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002410", "l": "plasmacytoid dendritic cell chemotaxis", "d": ["The movement of a plasmacytoid dendritic cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035634", "l": "response to stilbenoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060665", "l": "regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling", "d": ["Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071905", "l": "protein N-linked glucosylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106297", "l": "E-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0000096", "l": "sulfur amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900959", "l": "regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0030219", "l": "megakaryocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072240", "l": "metanephric DCT cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036011", "l": "imaginal disc-derived leg segmentation", "d": ["Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072204", "l": "cell-cell signaling involved in metanephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0180018", "l": "cytoplasmic polyadenylation-dependent RNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002658", "l": "regulation of peripheral tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of peripheral tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033067", "l": "macrolide metabolic process", "d": ["The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002559", "l": "type I hypersensitivity mediated by basophils", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061582", "l": "intestinal epithelial cell migration", "d": ["The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900584", "l": "o-orsellinic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of o-orsellinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990426", "l": "mitotic recombination-dependent replication fork processing", "d": ["Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016553", "l": "base conversion or substitution editing", "d": ["Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061963", "l": "regulation of entry into reproductive diapause", "d": ["Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052156", "l": "perturbation of host T-cell mediated immune response", "d": ["A process in which an organism effects a change that affects the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034697", "l": "response to prostaglandin I", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007105", "l": "cytokinesis, division site positioning", "d": ["The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901944", "l": "miltiradiene metabolic process", "d": ["The chemical reactions and pathways involving miltiradiene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021621", "l": "hypoglossal nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120308", "l": "axonemal outer doublet assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001211", "l": "negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021812", "l": "neuronal-glial interaction involved in cerebral cortex radial glia guided migration", "d": ["The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0052372", "l": "modulation by symbiont of entry into host", "d": ["Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0007140", "l": "male meiotic nuclear division", "d": ["A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035199", "l": "salt aversion", "d": ["The specific avoidance actions or reactions of an organism in response to the perception of salt."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002736", "l": "regulation of plasmacytoid dendritic cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039672", "l": "suppression by virus of host natural killer cell activation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051661", "l": "maintenance of centrosome location", "d": ["Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016037", "l": "light absorption", "d": ["The reception of a photon by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009299", "l": "mRNA transcription", "d": ["The cellular synthesis of messenger RNA (mRNA) from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035015", "l": "elongation of arista core", "d": ["The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010405", "l": "arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060860", "l": "regulation of floral organ abscission", "d": ["Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140244", "l": "regulation of translation at presynapse", "d": ["Any process that regulates translation occurring at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:1903038", "l": "negative regulation of leukocyte cell-cell adhesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140964", "l": "intracellular auxin homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of auxin within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.046396088509496", "identifiers": [{"i": "GO:0032990", "l": "cell part morphogenesis", "d": ["The process in which the anatomical structures of a cell part are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901448", "l": "regulation of response to butan-1-ol", "d": ["Any process that modulates the frequency, rate or extent of response to butan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901165", "l": "positive regulation of trophoblast cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of trophoblast cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120074", "l": "regulation of endocardial cushion cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900849", "l": "regulation of pseurotin A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002239", "l": "response to oomycetes", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150067", "l": "regulation of tubulin deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of tubulin deacetylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902460", "l": "regulation of mesenchymal stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902040", "l": "positive regulation of seed dormancy process", "d": ["Any process that activates or increases the frequency, rate or extent of seed dormancy process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000625", "l": "regulation of miRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016330", "l": "second mitotic wave involved in compound eye morphogenesis", "d": ["A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. 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A reproductive fruiting body is a multicellular reproductive structure that contains spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019991", "l": "septate junction assembly", "d": ["The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070455", "l": "positive regulation of heme biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160031", "l": "endoplasmic reticulum membrane biogenesis", "d": ["The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033198", "l": "response to ATP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006169", "l": "adenosine salvage", "d": ["Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016081", "l": "synaptic vesicle docking", "d": ["The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. 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The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0000052", "l": "citrulline metabolic process", "d": ["The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006711", "l": "estrogen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022019", "l": "dorsal lateral ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060532", "l": "bronchus cartilage development", "d": ["The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060604", "l": "mammary gland duct cavitation", "d": ["Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019515", "l": "lactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046740", "l": "transport of virus in host, cell to cell", "d": ["The transport of a virus between adjacent cells in a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905433", "l": "negative regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060449", "l": "bud elongation involved in lung branching", "d": ["The process in which a bud in the lung grows out from the point where it is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032600", "l": "chemokine receptor transport out of membrane raft", "d": ["The directed movement of a chemokine receptor out of a membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007535", "l": "donor selection", "d": ["The process that determines which donor locus a cell uses, in preference to another, in mating type switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0046474", "l": "glycerophospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0006081", "l": "cellular aldehyde metabolic process", "d": ["The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:1901653", "l": "cellular response to peptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0007552", "l": "metamorphosis", "d": ["A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901347", "l": "negative regulation of secondary cell wall biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014890", "l": "smooth muscle atrophy", "d": ["A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002901", "l": "mature B cell apoptotic process", "d": ["Any apoptotic process in a B cell that is mature, having left the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035387", "l": "negative regulation of Roundabout signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900550", "l": "N',N'',N'''-triacetylfusarinine C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.367368887635308", "identifiers": [{"i": "GO:0043086", "l": "negative regulation of catalytic activity", "d": ["Any process that stops or reduces the activity of an enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901801", "l": "1,5-anhydro-D-fructose metabolic process", "d": ["The chemical reactions and pathways involving 1,5-anhydro-D-fructose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061886", "l": "negative regulation of mini excitatory postsynaptic potential", "d": ["Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048393", "l": "intermediate mesodermal cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045986", "l": "negative regulation of smooth muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099153", "l": "synaptic transmission, serotonergic", "d": ["The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071392", "l": "cellular response to estradiol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0086036", "l": "regulation of cardiac muscle cell membrane potential", "d": ["Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901222", "l": "regulation of non-canonical NF-kappaB signal transduction", "d": ["Any process that modulates the frequency, rate or extent of the non-canonical NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003054", "l": "circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072116", "l": "pronephros formation", "d": ["The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141018", "l": "adhesion of symbiont to host via host extracellular matrix", "d": ["The attachment of a symbiont to its host by binding to a component of the host extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045905", "l": "positive regulation of translational termination", "d": ["Any process that activates or increases the frequency, rate or extent of translational termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032180", "l": "ubiquinone biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905941", "l": "positive regulation of gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140468", "l": "HRI-mediated signaling", "d": ["A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071650", "l": "negative regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904734", "l": "positive regulation of electron transfer activity", "d": ["Any process that activates or increases the frequency, rate or extent of electron transfer activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035477", "l": "regulation of angioblast cell migration involved in selective angioblast sprouting", "d": ["Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.885542599809028", "identifiers": [{"i": "GO:0042593", "l": "glucose homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of glucose within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904862", "l": "inhibitory synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045608", "l": "negative regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006016", "l": "2-deoxyribose 1-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030512", "l": "negative regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903638", "l": "positive regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901542", "l": "regulation of ent-pimara-8(14),15-diene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0017143", "l": "insecticide metabolic process", "d": ["The chemical reactions and pathways involving insecticides, chemicals used to kill insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0007136", "l": "meiotic prophase II", "d": ["The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000311", "l": "regulation of AMPA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072392", "l": "phenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0080120", "l": "CAAX-box protein maturation", "d": ["A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035443", "l": "tripeptide transmembrane transport", "d": ["The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071405", "l": "cellular response to methanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001128", "l": "methane biosynthetic process from methylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a methylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0062035", "l": "sensory perception of cold stimulus", "d": ["The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046190", "l": "aerobic phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061030", "l": "epithelial cell differentiation involved in mammary gland alveolus development", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046153", "l": "ommochrome catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140727", "l": "siRNA-dependent pericentric heterochromatin formation", "d": ["The formation of pericentric heterochromatin by a process mediated by a small interfering RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140466", "l": "iron-sulfur cluster export from the mitochondrion", "d": ["The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904528", "l": "positive regulation of microtubule binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044838", "l": "cell quiescence", "d": ["A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043615", "l": "astrocyte cell migration", "d": ["The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031290", "l": "retinal ganglion cell axon guidance", "d": ["The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042838", "l": "D-glucarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902474", "l": "positive regulation of protein localization to synapse", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900071", "l": "regulation of sulfite transport", "d": ["Any process that modulates the frequency, rate or extent of sulfite transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001969", "l": "regulation of activation of membrane attack complex", "d": ["Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0050770", "l": "regulation of axonogenesis", "d": ["Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903841", "l": "cellular response to arsenite(3-)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:1900377", "l": "negative regulation of secondary metabolite biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040039", "l": "inductive cell migration", "d": ["Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045168", "l": "cell-cell signaling involved in cell fate commitment", "d": ["Signaling at long or short range between cells that results in the commitment of a cell to a certain fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903652", "l": "modulation by virus of host cytoplasmic transport", "d": ["Modulation by an infecting virus of host cytoplasmic transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0099120", "l": "socially cooperative development", "d": ["The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034080", "l": "CENP-A containing chromatin assembly", "d": ["The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060847", "l": "endothelial cell fate specification", "d": ["The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905907", "l": "negative regulation of amyloid fibril formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071457", "l": "cellular response to ozone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002780", "l": "antibacterial peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0035107", "l": "appendage morphogenesis", "d": ["The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902327", "l": "bacterial-type DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in bacterial-type DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990961", "l": "xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043380", "l": "regulation of memory T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of memory T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.138589647363986", "identifiers": [{"i": "GO:0043067", "l": "regulation of programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000163", "l": "regulation of planar cell polarity pathway involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071545", "l": "inositol phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000214", "l": "regulation of proline metabolic process", "d": ["Any process that modulates the frequency, rate or extent of proline metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097278", "l": "complement-dependent cytotoxicity", "d": ["Cell killing caused by the membrane attack complex formed following complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902406", "l": "mitotic actomyosin contractile ring maturation", "d": ["The cellular process in which the mitotic contractile ring cytokinetic ring attains its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900114", "l": "positive regulation of histone H3-K9 trimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901537", "l": "positive regulation of DNA demethylation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA demethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001919", "l": "regulation of receptor recycling", "d": ["Any process that modulates the frequency, rate, or extent of receptor recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0006879", "l": "intracellular iron ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000304", "l": "positive regulation of ceramide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002281", "l": "macrophage activation involved in immune response", "d": ["A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036017", "l": "response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042705", "l": "ocellus photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031042", "l": "O-glycan processing, core 6", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018363", "l": "peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium", "d": ["The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032968", "l": "positive regulation of transcription elongation by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072107", "l": "positive regulation of ureteric bud formation", "d": ["Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062003", "l": "negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097116", "l": "gephyrin clustering involved in postsynaptic density assembly", "d": ["The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901968", "l": "regulation of polynucleotide 3'-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060503", "l": "bud dilation involved in lung branching", "d": ["The process in which a bud in the lung increases radially."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000012", "l": "regulation of auxin polar transport", "d": ["Any process that modulates the frequency, rate or extent of auxin polar transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035553", "l": "oxidative single-stranded RNA demethylation", "d": ["Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900179", "l": "positive regulation of aflatoxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0034501", "l": "protein localization to kinetochore", "d": ["Any process in which a protein is transported to, or maintained at, the kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0015994", "l": "chlorophyll metabolic process", "d": ["The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034117", "l": "erythrocyte aggregation", "d": ["The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0015697", "l": "quaternary ammonium group transport", "d": ["The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060297", "l": "regulation of sarcomere organization", "d": ["Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900379", "l": "regulation of asperthecin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070788", "l": "conidiophore stalk development", "d": ["The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060132", "l": "prolactin secreting cell development", "d": ["The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0010155", "l": "regulation of proton transport", "d": ["Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.122742264235399", "identifiers": [{"i": "GO:0098656", "l": "monoatomic anion transmembrane transport", "d": ["The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048665", "l": "neuron fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045109", "l": "intermediate filament organization", "d": ["Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062029", "l": "positive regulation of stress granule assembly", "d": ["Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021526", "l": "medial motor column neuron differentiation", "d": ["The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902872", "l": "regulation of horizontal cell localization", "d": ["Any process that modulates the frequency, rate or extent of horizontal cell localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140157", "l": "ammonium import across plasma membrane", "d": ["The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0015846", "l": "polyamine transport", "d": ["The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905380", "l": "regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032096", "l": "negative regulation of response to food", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903852", "l": "positive regulation of cristae formation", "d": ["Any process that activates or increases the frequency, rate or extent of cristae formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030279", "l": "negative regulation of ossification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002129", "l": "wobble position guanine ribose methylation", "d": ["The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099605", "l": "regulation of action potential firing rate", "d": ["Any process that regulates the frequency of action potentials in a spike train."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.133821031307569", "identifiers": [{"i": "GO:0042330", "l": "taxis", "d": ["The directed movement of a motile cell or organism in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090167", "l": "Golgi distribution to daughter cells", "d": ["Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046363", "l": "ribitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033341", "l": "regulation of collagen binding", "d": ["Any process that modulates the frequency, rate or extent of collagen binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090293", "l": "nitrogen catabolite regulation of transcription", "d": ["A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061283", "l": "specification of mesonephric distal tubule identity", "d": ["The process in which the distal tubule of the mesonephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033197", "l": "response to vitamin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032801", "l": "receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021659", "l": "rhombomere 3 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031536", "l": "positive regulation of exit from mitosis", "d": ["Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021581", "l": "medulla oblongata structural organization", "d": ["The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902954", "l": "regulation of early endosome to recycling endosome transport", "d": ["Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048940", "l": "anterior lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090716", "l": "adaptive immune memory response", "d": ["An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007089", "l": "traversing start control point of mitotic cell cycle", "d": ["A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052316", "l": "phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901088", "l": "benzylpenicillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzylpenicillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018305", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009229", "l": "thiamine diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0062098", "l": "regulation of programmed necrotic cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed necrotic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903279", "l": "regulation of calcium:sodium antiporter activity", "d": ["Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071581", "l": "regulation of zinc ion transmembrane import", "d": ["Any process that modulates the frequency, rate or extent of zinc ion import."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008542", "l": "visual learning", "d": ["Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046355", "l": "mannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035320", "l": "imaginal disc-derived wing hair site selection", "d": ["Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051939", "l": "gamma-aminobutyric acid import", "d": ["The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071026", "l": "cytoplasmic RNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007460", "l": "R8 cell fate commitment", "d": ["The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061210", "l": "cell-cell signaling involved in mesonephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904302", "l": "negative regulation of maternal process involved in parturition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0009746", "l": "response to hexose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042075", "l": "nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "d": ["The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035759", "l": "mesangial cell-matrix adhesion", "d": ["The binding of a mesangial cell to the extracellular matrix via adhesion molecules. 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The blood vessel is the vasculature carrying blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110134", "l": "meiotic drive", "d": ["A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052096", "l": "formation of syncytium involving giant cell for nutrient acquisition", "d": ["The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001171", "l": "reverse transcription", "d": ["A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000017", "l": "alpha-glucoside transport", "d": ["The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901038", "l": "cyanidin 3-O-glucoside metabolic process", "d": ["The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071228", "l": "cellular response to tumor cell", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031288", "l": "sorocarp morphogenesis", "d": ["The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0071555", "l": "cell wall organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030451", "l": "regulation of complement activation, alternative pathway", "d": ["Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072274", "l": "metanephric glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0043011", "l": "myeloid dendritic cell differentiation", "d": ["The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901383", "l": "negative regulation of chorionic trophoblast cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009724", "l": "detection of abscisic acid stimulus", "d": ["The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001127", "l": "methane biosynthetic process from formic acid", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0044002", "l": "acquisition of nutrients from host", "d": ["The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160057", "l": "plant endodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a plant endodermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060024", "l": "rhythmic synaptic transmission", "d": ["Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0019079", "l": "viral genome replication", "d": ["Any process involved directly in viral genome replication, including viral nucleotide metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033621", "l": "nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH 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RNA, where it is a minor base."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0044182", "l": "filamentous growth of a population of unicellular organisms", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061551", "l": "trigeminal ganglion development", "d": ["The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098714", "l": "malate import across plasma membrane", "d": ["The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010404", "l": "cell wall hydroxyproline-rich glycoprotein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902318", "l": "synthesis of RNA primer involved in nuclear cell cycle DNA replication", "d": ["Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071630", "l": "nuclear protein quality control by the ubiquitin-proteasome system", "d": ["The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043286", "l": "regulation of poly(3-hydroxyalkanoate) biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000260", "l": "regulation of blood coagulation, common pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, common pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098822", "l": "peptidyl-cysteine modification to L-cysteine persulfide", "d": ["The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072162", "l": "metanephric mesenchymal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075137", "l": "response to host redox environment", "d": ["Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021540", "l": "corpus callosum morphogenesis", "d": ["The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035824", "l": "long tract gene conversion", "d": ["A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900513", "l": "negative regulation of starch utilization system complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001929", "l": "negative regulation of exocyst assembly", "d": ["Any process that stops, prevents, or reduces the rate or extent of exocyst assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000035", "l": "regulation of stem cell division", "d": ["Any process that modulates the frequency, rate or extent of stem cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089704", "l": "L-glutamate transmembrane export from vacuole", "d": ["The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033493", "l": "esculetin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0090497", "l": "mesenchymal cell migration", "d": ["The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090211", "l": "positive regulation of establishment of blood-brain barrier", "d": ["Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072153", "l": "renal interstitial fibroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046061", "l": "dATP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019316", "l": "D-allose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000023", "l": "maltose metabolic process", "d": ["The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035892", "l": "perturbation of platelet aggregation in another organism", "d": ["The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042777", "l": "proton motive force-driven plasma membrane ATP synthesis", "d": ["The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006191", "l": "deoxyinosine salvage", "d": ["Any process that generates deoxyinosine from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0019049", "l": "mitigation of host antiviral defense response", "d": ["A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042676", "l": "compound eye cone cell fate commitment", "d": ["The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903303", "l": "negative regulation of pyruvate kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905551", "l": "negative regulation of protein localization to endoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903216", "l": "regulation of protein processing involved in protein targeting to mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035342", "l": "positive regulation of inosine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901872", "l": "ecgonone methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecgonone methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110139", "l": "negative regulation of imaginal disc-derived leg joint morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904563", "l": "phosphatidylinositol 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902497", "l": "iron-sulfur cluster transmembrane transport", "d": ["A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.489128680191399", "identifiers": [{"i": "GO:0016043", "l": "cellular component organization", "d": ["A process that results 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"90.82444074280258", "identifiers": [{"i": "GO:1902900", "l": "gut granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gut granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903615", "l": "positive regulation of protein tyrosine phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0043649", "l": "dicarboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904838", "l": "regulation of male germ-line stem cell asymmetric division", "d": ["Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.687271825765198", "identifiers": [{"i": "GO:0019538", "l": "protein metabolic process", "d": ["The chemical reactions and pathways involving a protein. Includes protein modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051617", "l": "negative regulation of histamine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903872", "l": "regulation of DNA recombinase mediator complex assembly", "d": ["Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000564", "l": "regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090181", "l": "regulation of cholesterol metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032082", "l": "negative regulation of type III site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0061537", "l": "glycine secretion, neurotransmission", "d": ["The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033089", "l": "positive regulation of T cell differentiation in thymus", "d": ["Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019075", "l": "virus maturation", "d": ["The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071037", "l": "nuclear polyadenylation-dependent snRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003317", "l": "cardioblast cell midline fusion", "d": ["The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051878", "l": "lateral element assembly", "d": ["The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016038", "l": "absorption of visible light", "d": ["The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1904672", "l": "regulation of somatic stem cell population maintenance", "d": ["Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072100", "l": "specification of ureteric bud anterior/posterior symmetry", "d": ["The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001290", "l": "hydroperoxide metabolic process", "d": ["The chemical reactions and pathways involving a hydroperoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0031397", "l": "negative regulation of protein ubiquitination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046320", "l": "regulation of fatty acid oxidation", "d": ["Any process that modulates the frequency, rate or extent of fatty acid oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001868", "l": "regulation of complement activation, lectin pathway", "d": ["Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902691", "l": "respiratory basal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902034", "l": "negative regulation of hematopoietic stem cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070980", "l": "biphenyl catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060919", "l": "auxin import into cell", "d": ["The directed movement of auxins from outside of a cell into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046797", "l": "viral procapsid maturation", "d": ["The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030046", "l": "parallel actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031133", "l": "regulation of axon diameter", "d": ["Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0006274", "l": "DNA replication termination", "d": ["The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060208", "l": "proestrus", "d": ["The estrous cycle phase in which there is heightened follicular activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090272", "l": "negative regulation of fibroblast growth factor production", "d": ["Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0072676", "l": "lymphocyte migration", "d": ["The movement of a lymphocyte within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044727", "l": "epigenetic programing of male pronucleus", "d": ["The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.387656307797414", "identifiers": [{"i": "GO:0035592", "l": "establishment of protein localization to extracellular region", "d": ["The directed movement of a protein to a specific location within the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:2000050", "l": "regulation of non-canonical Wnt signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010444", "l": "guard mother cell differentiation", "d": ["The process in which a meristemoid acquires the specialized features of a guard mother cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904787", "l": "positive regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018140", "l": "peptide cross-linking via L-cysteine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0070726", "l": "cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990155", "l": "Dsc E3 ubiquitin ligase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904380", "l": "endoplasmic reticulum mannose trimming", "d": ["Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048133", "l": "male germ-line stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001994", "l": "norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure", "d": ["A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097170", "l": "ADP-L-glycero-beta-D-manno-heptose metabolic process", "d": ["The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033302", "l": "quercetin O-glucoside metabolic process", "d": ["The chemical reactions and pathways involving O-glucosylated derivatives of quercetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034620", "l": "cellular response to unfolded protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097293", "l": "XMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0010466", "l": "negative regulation of peptidase activity", "d": ["Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000922", "l": "negative regulation of arabinoxylan-containing compound catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902982", "l": "DNA strand elongation involved in premeiotic DNA replication", "d": ["Any DNA strand elongation involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035336", "l": "long-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010415", "l": "unsubstituted mannan metabolic process", "d": ["The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001310", "l": "gliotoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048866", "l": "stem cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904970", "l": "brush border assembly", "d": ["The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033324", "l": "choline biosynthetic process via N-monomethylethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033527", "l": "tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007470", "l": "prothoracic disc morphogenesis", "d": ["The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001546", "l": "preantral ovarian follicle growth", "d": ["Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090024", "l": "negative regulation of neutrophil chemotaxis", "d": ["Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.920847010046863", "identifiers": [{"i": "GO:1902531", "l": "regulation of intracellular signal transduction", "d": ["Any process that modulates the frequency, rate or extent of intracellular signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036510", "l": "trimming of terminal mannose on C branch", "d": ["The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903084", "l": "protein localization to condensed nuclear chromosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021525", "l": "lateral motor column neuron differentiation", "d": ["The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0039007", "l": "pronephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902618", "l": "cellular response to fluoride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0160077", "l": "lipid droplet fusion", "d": ["The process by which a single lipid droplet is created from the fusion of two or more lipid droplets."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000714", "l": "meiotic strand displacement", "d": ["The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018187", "l": "molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide", "d": ["The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000772", "l": "regulation of cellular senescence", "d": ["Any process that modulates the frequency, rate or extent of cellular senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0009743", "l": "response to carbohydrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072464", "l": "response to meiotic spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015778", "l": "hexuronide transmembrane transport", "d": ["The directed movement of hexuronide across a membrane. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080126", "l": "ovary septum development", "d": ["The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140321", "l": "symbiont-mediated suppression of host autophagy", "d": ["Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032471", "l": "negative regulation of endoplasmic reticulum calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071485", "l": "cellular response to absence of light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032701", "l": "negative regulation of interleukin-18 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032077", "l": "positive regulation of deoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061843", "l": "Sertoli cell barrier remodeling", "d": ["The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042870", "l": "D-glucarate transmembrane transport", "d": ["The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003369", "l": "establishment of cell polarity involved in mesendodermal cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140334", "l": "lipopolysaccharide localization to cell outer membrane", "d": ["A process in which a lipopolysaccharide is transported to the cell outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071932", "l": "replication fork reversal", "d": ["Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140423", "l": "effector-mediated suppression of host pattern-triggered immunity signaling", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0061984", "l": "catabolite repression", "d": ["A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046129", "l": "purine ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046007", "l": "negative regulation of activated T cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903146", "l": "regulation of autophagy of mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061302", "l": "smooth muscle cell-matrix adhesion", "d": ["The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060637", "l": "positive regulation of lactation by mesenchymal-epithelial cell signaling", "d": ["The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002397", "l": "MHC class I protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903691", "l": "positive regulation of wound healing, spreading of epidermal cells", "d": ["Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060844", "l": "arterial endothelial cell fate commitment", "d": ["The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034616", "l": "response to laminar fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0007033", "l": "vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901922", "l": "regulation of sclerotium development", "d": ["Any process that modulates the frequency, rate or extent of sclerotium development."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0030435", "l": "sporulation resulting in formation of a cellular spore", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009732", "l": "detection of hexose stimulus", "d": ["The series of events in which a stimulus from a hexose is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045227", "l": "capsule polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0046692", "l": "sperm competition", "d": ["Any process that contributes to the success of sperm fertilization in multiply-mated females."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019450", "l": "L-cysteine catabolic process to pyruvate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034087", "l": "establishment of mitotic sister chromatid cohesion", "d": ["The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071592", "l": "nicotinic acid riboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120273", "l": "ciliary centrin arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900961", "l": "positive regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1902101", "l": "positive regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905168", "l": "positive regulation of double-strand break repair via homologous recombination", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036399", "l": "TCR signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902272", "l": "regulation of (R)-carnitine transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.400267550270534", "identifiers": [{"i": "GO:0051641", "l": "cellular localization", "d": ["A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001309", "l": "gliotoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010497", "l": "plasmodesmata-mediated intercellular transport", "d": ["The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019546", "l": "arginine deiminase pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033542", "l": "fatty acid beta-oxidation, unsaturated, even number", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015756", "l": "fucose transmembrane transport", "d": ["The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075280", "l": "regulation of uredinium development", "d": ["Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046045", "l": "TMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900208", "l": "regulation of cardiolipin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cardiolipin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140974", "l": "cellular detoxification of sulfide", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046830", "l": "positive regulation of RNA import into nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018878", "l": "aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046317", "l": "regulation of glucosylceramide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000573", "l": "positive regulation of DNA biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044846", "l": "negative regulation by symbiont of indole acetic acid levels in host", "d": ["Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0097581", "l": "lamellipodium organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904650", "l": "negative regulation of fat cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019509", "l": "L-methionine salvage from methylthioadenosine", "d": ["The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099089", "l": "establishment of endoplasmic reticulum localization to postsynapse", "d": ["The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002086", "l": "diaphragm contraction", "d": ["A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060305", "l": "regulation of cell diameter", "d": ["Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072762", "l": "cellular response to carbendazim", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009225", "l": "nucleotide-sugar metabolic process", "d": ["The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030835", "l": "negative regulation of actin filament depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009082", "l": "branched-chain amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0016079", "l": "synaptic vesicle exocytosis", "d": ["Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061743", "l": "motor learning", "d": ["Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014011", "l": "Schwann cell proliferation involved in axon regeneration", "d": ["The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0046364", "l": "monosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905445", "l": "positive regulation of clathrin coat assembly", "d": ["Any process that activates or increases the frequency, rate or extent of clathrin coat assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060045", "l": "positive regulation of cardiac muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905888", "l": "negative regulation of cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090121", "l": "low-density lipoprotein particle disassembly involved in cholesterol transport", "d": ["The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900838", "l": "negative regulation of fumigaclavine C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072225", "l": "metanephric late distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000315", "l": "positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002024", "l": "diet induced thermogenesis", "d": ["The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060658", "l": "nipple morphogenesis", "d": ["The process in which the nipple is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021503", "l": "neural fold bending", "d": ["The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009445", "l": "putrescine metabolic process", "d": ["The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018403", "l": "protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009232", "l": "riboflavin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071836", "l": "nectar secretion", "d": ["The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044470", "l": "envenomation resulting in negative regulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0031123", "l": "RNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990656", "l": "t-SNARE clustering", "d": ["The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042069", "l": "regulation of catecholamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903179", "l": "regulation of dopamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of dopamine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0035601", "l": "protein deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.576180114155946", "identifiers": [{"i": "GO:0002822", "l": "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035761", "l": "dorsal motor nucleus of vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019650", "l": "glycolytic fermentation to butanediol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905830", "l": "positive regulation of prostaglandin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097579", "l": "extracellular sequestering of copper ion", "d": ["The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901472", "l": "regulation of Golgi calcium ion export", "d": ["Any process that modulates the frequency, rate or extent of Golgi calcium ion export."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042353", "l": "fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045917", "l": "positive regulation of complement activation", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000526", "l": "positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation", "d": ["Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903589", "l": "positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901781", "l": "p-cumate metabolic process", "d": ["The chemical reactions and pathways involving p-cumate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055121", "l": "response to high fluence blue light stimulus by blue high-fluence system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0018131", "l": "oxazole or thiazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903572", "l": "positive regulation of protein kinase D signaling", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase D signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002632", "l": "negative regulation of granuloma formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0003031", "l": "detection of carbon dioxide", "d": ["The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050830", "l": "defense response to Gram-positive bacterium", "d": ["Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009995", "l": "soluble molecule recognition", "d": ["The recognition of soluble molecules in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051609", "l": "inhibition of neurotransmitter uptake", "d": ["Any process that prevents the activation of the directed movement of a neurotransmitter into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000014", "l": "regulation of endosperm development", "d": ["Any process that modulates the frequency, rate or extent of endosperm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106402", "l": "Lewis x epitope biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006697", "l": "ecdysone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060261", "l": "positive regulation of transcription initiation by RNA polymerase II", "d": ["Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060384", "l": "innervation", "d": ["The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010128", "l": "benzoate catabolic process via CoA ligation", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031495", "l": "negative regulation of mating type switching", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904294", "l": "positive regulation of ERAD pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERAD pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990762", "l": "cytoplasmic alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097702", "l": "response to oscillatory fluid shear stress", "d": ["Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0043903", "l": "regulation of biological process involved in symbiotic interaction", "d": ["Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000975", "l": "positive regulation of pro-B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006561", "l": "proline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007258", "l": "JUN phosphorylation", "d": ["The process of introducing a phosphate group into a JUN protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905281", "l": "positive regulation of retrograde transport, endosome to Golgi", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0017015", "l": "regulation of transforming growth factor beta receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039722", "l": "suppression by virus of host toll-like receptor signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048611", "l": "embryonic ectodermal digestive tract development", "d": ["The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0003158", "l": "endothelium development", "d": ["The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140255", "l": "regulation of cellular response to phosphate starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904310", "l": "cellular response to cordycepin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071433", "l": "cell wall repair", "d": ["A process of cell wall organization that results in the restoration of the cell wall following damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0044646", "l": "envenomation resulting in modulation of complement activation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045747", "l": "positive regulation of Notch signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009074", "l": "aromatic amino acid family catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.930404882604968", "identifiers": [{"i": "GO:0010558", "l": "negative regulation of macromolecule biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019447", "l": "D-cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001123", "l": "maltoheptaose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a maltoheptaose."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042823", "l": "pyridoxal phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010744", "l": "positive regulation of macrophage derived foam cell differentiation", "d": ["Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0045017", "l": "glycerolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098841", "l": "protein localization to cell division site after cytokinesis", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904596", "l": "regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that modulates the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010059", "l": "positive regulation of atrichoblast fate specification", "d": ["Any process that induces or promotes atrichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044558", "l": "uterine smooth muscle relaxation", "d": ["A process in which the extent of smooth muscle contraction is reduced in the uterus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093002", "l": "response to nematicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086052", "l": "membrane repolarization during SA node cell action potential", "d": ["The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070973", "l": "protein localization to endoplasmic reticulum exit site", "d": ["A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075029", "l": "formation of appressorium germ tube hook structure", "d": ["The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090058", "l": "metaxylem development", "d": ["The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061723", "l": "glycophagy", "d": ["The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009191", "l": "ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0050832", "l": "defense response to fungus", "d": ["Reactions triggered in response to the presence of a fungus that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000915", "l": "regulation of glucuronoxylan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061704", "l": "glycolytic process from sucrose", "d": ["The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905338", "l": "negative regulation of cohesin unloading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060910", "l": "negative regulation of DNA replication initiation involved in plasmid copy number maintenance", "d": ["Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043302", "l": "positive regulation of leukocyte degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905426", "l": "positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033244", "l": "regulation of penicillin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035118", "l": "embryonic pectoral fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903961", "l": "positive regulation of anion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of anion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000494", "l": "positive regulation of interleukin-18-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006311", "l": "meiotic gene conversion", "d": ["The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016332", "l": "establishment or maintenance of polarity of embryonic epithelium", "d": ["Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009154", "l": "purine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033689", "l": "negative regulation of osteoblast proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009085", "l": "lysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090138", "l": "regulation of actin cytoskeleton organization by cell-cell adhesion", "d": ["Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902641", "l": "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902344", "l": "negative regulation of maltose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035247", "l": "peptidyl-arginine omega-N-methylation", "d": ["The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0048682", "l": "sprouting of injured axon", "d": ["The process involved in sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021849", "l": "neuroblast division in subventricular zone", "d": ["The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098934", "l": "retrograde dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009627", "l": "systemic acquired resistance", "d": ["The salicylic acid mediated response to a pathogen which confers broad spectrum resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018214", "l": "protein carboxylation", "d": ["The addition of a carboxy group to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.63134278132528", "identifiers": [{"i": "GO:0048589", "l": "developmental growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0072202", "l": "cell differentiation involved in metanephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903868", "l": "regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904197", "l": "positive regulation of granulosa cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046639", "l": "negative regulation of alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090548", "l": "response to nitrate starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900146", "l": "negative regulation of nodal signaling pathway involved in determination of left/right asymmetry", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098535", "l": "de novo centriole assembly involved in multi-ciliated epithelial cell differentiation", "d": ["Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032080", "l": "negative regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016121", "l": "carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060659", "l": "nipple sheath formation", "d": ["The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. 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This can happen through heterochromatin formation or differential chromatin loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072753", "l": "cellular response to glutathione", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905824", "l": "positive regulation of mitotic sister chromatid arm separation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035623", "l": "renal glucose absorption", "d": ["A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. 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In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.858950277264299", "identifiers": [{"i": "GO:1901990", "l": "regulation of mitotic cell cycle phase transition", "d": ["Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036485", "l": "dorsolateral trunk neural crest cell migration", "d": ["The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0110156", "l": "methylguanosine-cap decapping", "d": ["Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042204", "l": "s-triazine compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150038", "l": "postsynaptic dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0060839", "l": "endothelial cell fate commitment", "d": ["The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032295", "l": "ensheathment of neuronal cell bodies", "d": ["The process in which satellite glial cells isolate neuronal cell bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043077", "l": "initiation of acetate catabolic process", "d": ["The activation of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042956", "l": "maltodextrin transmembrane transport", "d": ["The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902543", "l": "negative regulation of protein localization to mitotic spindle pole body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0055007", "l": "cardiac muscle cell differentiation", "d": ["The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. 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MPA is the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900458", "l": "negative regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903133", "l": "negative regulation of tube lumen cavitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035362", "l": "protein-DNA ISRE complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003410", "l": "anterior rotation of the optic cup", "d": ["A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905751", "l": "positive regulation of endosome to plasma membrane protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019391", "l": "glucuronoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035746", "l": "granzyme A production", "d": ["The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032961", "l": "negative regulation of inositol trisphosphate biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090037", "l": "positive regulation of protein kinase C signaling", "d": ["Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900562", "l": "dehydroaustinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dehydroaustinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032755", "l": "positive regulation of interleukin-6 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-6 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010224", "l": "response to UV-B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031951", "l": "positive regulation of glucocorticoid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002042", "l": "cell migration involved in sprouting angiogenesis", "d": ["The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903646", "l": "positive regulation of chaperone-mediated protein folding", "d": ["Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.105588726333181", "identifiers": [{"i": "GO:0002376", "l": "immune system process", "d": ["Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045612", "l": "positive regulation of hemocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hemocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048860", "l": "glioblast division", "d": ["The process resulting in the physical partitioning and separation of a glioblast into daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904992", "l": "positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904902", "l": "ESCRT III complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1900864", "l": "mitochondrial RNA modification", "d": ["Any RNA modification that takes place in mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140114", "l": "cellular detoxification of fluoride", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903301", "l": "positive regulation of hexokinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hexokinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902849", "l": "positive regulation of neuronal signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of neuronal signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015960", "l": "diadenosine polyphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021750", "l": "vestibular nucleus development", "d": ["The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009594", "l": "detection of nutrient", "d": ["The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090384", "l": "phagosome-lysosome docking", "d": ["The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045197", "l": "establishment or maintenance of epithelial cell apical/basal polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080160", "l": "selenate transport", "d": ["The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042660", "l": "positive regulation of cell fate specification", "d": ["Any process that activates or enables a cell to adopt a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903257", "l": "selenoneine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of selenoneine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014827", "l": "intestine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.132204334157755", "identifiers": [{"i": "GO:0006304", "l": "DNA modification", "d": ["The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070947", "l": "neutrophil-mediated killing of fungus", "d": ["The directed killing of a fungal cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019369", "l": "arachidonic acid metabolic process", "d": ["The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018281", "l": "GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine", "d": ["The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042216", "l": "phenanthrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033478", "l": "UDP-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098996", "l": "disruption of host cell glycocalyx during viral entry", "d": ["The disruption of host cell glycocalyx by viral proteins during virus entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901045", "l": "negative regulation of egg-laying behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oviposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902868", "l": "positive regulation of retina development in camera-type eye", "d": ["Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006001", "l": "fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035358", "l": "regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902548", "l": "negative regulation of cellular response to vascular endothelial growth factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902251", "l": "negative regulation of erythrocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002528", "l": "regulation of vascular permeability involved in acute inflammatory response", "d": ["Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010069", "l": "zygote asymmetric cytokinesis in embryo sac", "d": ["The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010185", "l": "regulation of cellular defense response", "d": ["Any process that modulates the frequency, rate or extent of cellular defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061264", "l": "mesonephric glomerular mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003361", "l": "noradrenergic neuron differentiation involved in brainstem development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905023", "l": "positive regulation of threonine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045624", "l": "positive regulation of T-helper cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000150", "l": "regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904381", "l": "Golgi apparatus mannose trimming", "d": ["Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048653", "l": "anther development", "d": ["The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051041", "l": "positive regulation of calcium-independent cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0006563", "l": "L-serine metabolic process", "d": ["The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900899", "l": "regulation of heptadecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of heptadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060059", "l": "embryonic retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072259", "l": "metanephric interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902333", "l": "nuclear DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.176222887335875", "identifiers": [{"i": "GO:0051173", "l": "positive regulation of nitrogen compound metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.20383166423133", "identifiers": [{"i": "GO:0035148", "l": "tube formation", "d": ["Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003262", "l": "endocardial progenitor cell migration to the midline involved in heart field formation", "d": ["The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090095", "l": "regulation of metanephric cap mesenchymal cell proliferation", "d": ["Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901469", "l": "regulation of syringal lignin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of syringal lignin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010782", "l": "proboscis morphogenesis, labial disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070966", "l": "nuclear-transcribed mRNA catabolic process, no-go decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905204", "l": "negative regulation of connective tissue replacement", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010979", "l": "regulation of vitamin D 24-hydroxylase activity", "d": ["Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.201324080598809", "identifiers": [{"i": "GO:0016331", "l": "morphogenesis of embryonic epithelium", "d": ["The process in which the anatomical structures of embryonic epithelia are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031100", "l": "animal organ regeneration", "d": ["The regrowth of a lost or destroyed animal organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0060581", "l": "cell fate commitment involved in pattern specification", "d": ["The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033005", "l": "positive regulation of mast cell activation", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032687", "l": "negative regulation of interferon-alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.178947519258699", "identifiers": [{"i": "GO:0006812", "l": "monoatomic cation transport", "d": ["The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031651", "l": "negative regulation of heat generation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.618744678332945", "identifiers": [{"i": "GO:0015931", "l": "nucleobase-containing compound transport", "d": ["The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060652", "l": "mammary gland cord morphogenesis", "d": ["The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048865", "l": "stem cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006657", "l": "CDP-choline pathway", "d": ["The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002382", "l": "regulation of tissue kallikrein-kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020028", "l": "endocytic hemoglobin import into cell", "d": ["The directed movement of hemoglobin into a cell by receptor-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035764", "l": "dorsal motor nucleus of vagus nerve formation", "d": ["The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034265", "l": "isopentenyl adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0060441", "l": "epithelial tube branching involved in lung morphogenesis", "d": ["The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097320", "l": "plasma membrane tubulation", "d": ["A membrane tubulation process occurring in a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048548", "l": "regulation of pinocytosis", "d": ["Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905451", "l": "positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034478", "l": "phosphatidylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120196", "l": "negative regulation of anther dehiscence", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905276", "l": "regulation of epithelial tube formation", "d": ["Any process that modulates the frequency, rate or extent of epithelial tube formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.634102831637321", "identifiers": [{"i": "GO:2000145", "l": "regulation of cell motility", "d": ["Any process that modulates the frequency, rate or extent of cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120318", "l": "olfactory sociosexual communication", "d": ["The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010387", "l": "COP9 signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016143", "l": "S-glycoside metabolic process", "d": ["The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061209", "l": "cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120190", "l": "negative regulation of bile acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018377", "l": "protein myristoylation", "d": ["The covalent attachment of a myristoyl group to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051298", "l": "centrosome duplication", "d": ["The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0072522", "l": "purine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030239", "l": "myofibril assembly", "d": ["Formation of myofibrils, the repeating units of striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071380", "l": "cellular response to prostaglandin E stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021636", "l": "trigeminal nerve morphogenesis", "d": ["The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071283", "l": "cellular response to iron(III) ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120127", "l": "response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009711", "l": "purine alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075012", "l": "negative regulation of germ tube formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990116", "l": "ribosome-associated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019537", "l": "vibriobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032485", "l": "regulation of Ral protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ral protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036298", "l": "recombinational interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033075", "l": "isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.528927212007765", "identifiers": [{"i": "GO:0022600", "l": "digestive system process", "d": ["A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106116", "l": "positive regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048642", "l": "negative regulation of skeletal muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021991", "l": "neural plate thickening", "d": ["The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900928", "l": "positive regulation of L-threonine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-threonine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1901985", "l": "positive regulation of protein acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016360", "l": "sensory organ precursor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009777", "l": "photosynthetic phosphorylation", "d": ["Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034193", "l": "L-galactonate metabolic process", "d": ["The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015916", "l": "fatty-acyl-CoA transport", "d": ["The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000090", "l": "regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036149", "l": "phosphatidylinositol acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150117", "l": "positive regulation of cell-substrate junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090267", "l": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0014888", "l": "striated muscle adaptation", "d": ["Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900027", "l": "regulation of ruffle assembly", "d": ["Any process that modulates the frequency, rate or extent of ruffle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006586", "l": "indolalkylamine metabolic process", "d": ["The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033486", "l": "delphinidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a 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guanosine-cytidine insertion", "d": ["The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0033014", "l": "tetrapyrrole biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046383", "l": "dTDP-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904030", "l": "negative regulation of cyclin-dependent protein kinase activity", "d": ["Any 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N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099163", "l": "synaptic signaling by nitric oxide", "d": ["Cell-cell signaling to or from a synapse, mediated by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140883", "l": "induction by virus of host reticulophagy", "d": ["Any process in which a virus activates or increases the frequency, rate or extent of reticulophagy in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002915", "l": "negative regulation of central B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990559", "l": "mitochondrial coenzyme A transmembrane transport", "d": ["The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034232", "l": "ascospore wall chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033355", "l": "ascorbate glutathione cycle", "d": ["A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001925", "l": "negative regulation of B-1 B cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of B-1 B cell 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development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016258", "l": "N-glycan diversification", "d": ["The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903533", "l": "regulation of protein targeting", "d": ["Any process that modulates the frequency, rate or extent of protein targeting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045701", "l": "negative regulation of spermatid nuclear differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110058", "l": "positive regulation of blood vessel endothelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120278", "l": "negative regulation of cerebral blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900195", "l": "positive regulation of oocyte maturation", "d": ["Any process that activates or increases the frequency, rate or extent of oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030954", "l": "astral microtubule nucleation", "d": ["The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000236", "l": "negative regulation of tRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009990", "l": "contact guidance", "d": ["Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033195", "l": "response to alkyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0055115", "l": "entry into diapause", "d": ["The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900960", "l": "negative regulation of 17-methylnonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060640", "l": "positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling", "d": ["Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061931", "l": "positive regulation of erythrocyte enucleation", "d": ["Any process that increases the frequency, rate or extent of erythrocyte enucleation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001208", "l": "negative regulation of transcription elongation by RNA polymerase I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043611", "l": "isoprene metabolic process", "d": ["The chemical reactions and pathways involving isoprene, C5H8."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140977", "l": "cellular detoxification of acetone", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of acetone. These may include chemical modification, for example to methylglyoxal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014900", "l": "muscle hyperplasia", "d": ["A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003323", "l": "type B pancreatic cell development", "d": ["The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060674", "l": "placenta blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901167", "l": "3-chlorocatechol metabolic process", "d": ["The chemical reactions and pathways involving 3-chlorocatechol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070262", "l": "peptidyl-serine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035294", "l": "determination of wing disc primordium", "d": ["Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0022413", "l": "reproductive process in single-celled organism", "d": ["A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0003413", "l": "chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030588", "l": "pseudocleavage", "d": ["Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032735", "l": "positive regulation of interleukin-12 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-12 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036518", "l": "chemorepulsion of dopaminergic neuron axon", "d": ["The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904102", "l": "cellular response to acadesine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048651", "l": "polyphenic determination, influence by environmental factors", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032959", "l": "inositol trisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015820", "l": "leucine transport", "d": ["The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0001977", "l": "renal system process involved in regulation of blood volume", "d": ["A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0021545", "l": "cranial nerve development", "d": ["The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002663", "l": "positive regulation of B cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000548", "l": "negative regulation of dendritic cell dendrite assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019762", "l": "glucosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048324", "l": "regulation of axial mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018533", "l": "peptidyl-cysteine acetylation", "d": ["The acetylation of peptidyl-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905841", "l": "response to oxidopamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032793", "l": "positive regulation of CREB transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902184", "l": "negative regulation of shoot apical meristem development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903934", "l": "positive regulation of DNA primase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA primase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905709", "l": "negative regulation of membrane permeability", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0097194", "l": "execution phase of apoptosis", "d": ["A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904664", "l": "negative regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019673", "l": "GDP-mannose metabolic process", "d": ["The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903625", "l": "negative regulation of DNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901829", "l": "zeaxanthin bis(beta-D-glucoside) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902447", "l": "negative regulation of shade avoidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042531", "l": "positive regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902168", "l": "response to catechin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006598", "l": "polyamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0061536", "l": "glycine secretion", "d": ["The controlled release of glycine by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031108", "l": "holo-[acyl-carrier-protein] biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0060026", "l": "convergent extension", "d": ["The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034589", "l": "hydroxyproline transport", "d": ["The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035964", "l": "COPI-coated vesicle budding", "d": ["The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903368", "l": "regulation of foraging behavior", "d": ["Any process that modulates the frequency, rate or extent of foraging behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0048240", "l": "sperm capacitation", "d": ["A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903997", "l": "positive regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098514", "l": "detection of high humidity stimulus involved in sensory perception", "d": ["The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0043938", "l": "positive regulation of sporulation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902390", "l": "regulation of N-terminal peptidyl-serine acetylation", "d": ["Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061968", "l": "maintenance of left/right asymmetry", "d": ["The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0031342", "l": "negative regulation of cell killing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904280", "l": "negative regulation of transcription by RNA polymerase V", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035775", "l": "pronephric glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903982", "l": "negative regulation of microvillus length", "d": ["A process that decreases the length of a microvillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060612", "l": "adipose tissue development", "d": ["The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042082", "l": "GSI anchor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015796", "l": "galactitol transmembrane transport", "d": ["The directed movement of galactitol across a membrane. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090425", "l": "acinar cell differentiation", "d": ["The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903140", "l": "regulation of establishment of endothelial barrier", "d": ["Any process that modulates the frequency, rate or extent of establishment of endothelial barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051105", "l": "regulation of DNA ligation", "d": ["Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044564", "l": "envenomation resulting in occlusion of the pore of voltage-gated potassium channel in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032285", "l": "non-myelinated axon ensheathment", "d": ["The process in which a non-myelinating glial cell membrane closes around an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0009821", "l": "alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010967", "l": "regulation of polyamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042396", "l": "phosphagen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090675", "l": "intermicrovillar adhesion", "d": ["The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007295", "l": "growth of a germarium-derived egg chamber", "d": ["Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901800", "l": "positive regulation of proteasomal protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0016109", "l": "tetraterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900290", "l": "positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902278", "l": "positive regulation of pancreatic amylase secretion", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.019303412275349", "identifiers": [{"i": "GO:0048284", "l": "organelle fusion", "d": ["The creation of a single organelle from two or more organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046668", "l": "regulation of retinal cell programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072583", "l": "clathrin-dependent endocytosis", "d": ["An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031115", "l": "negative regulation of microtubule polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032120", "l": "ascospore-type prospore membrane formation", "d": ["The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070871", "l": "cell wall organization involved in conjugation with cellular fusion", "d": ["A process of cell wall organization that contributes to conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903803", "l": "L-glutamine import across plasma membrane", "d": ["The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903001", "l": "negative regulation of lipid transport across blood-brain barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019376", "l": "galactolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060011", "l": "Sertoli cell proliferation", "d": ["The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061924", "l": "regulation of formation of radial glial scaffolds", "d": ["Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043441", "l": "acetoacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120141", "l": "regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032341", "l": "aldosterone metabolic process", "d": ["The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001178", "l": "regulation of transcriptional start site selection at RNA polymerase II promoter", "d": ["Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021981", "l": "subpallium radially oriented migration", "d": ["The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010271", "l": "regulation of chlorophyll catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904372", "l": "positive regulation of protein localization to actin cortical patch", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052322", "l": "positive regulation of phytoalexin biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046657", "l": "folic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070709", "l": "RNA guanosine insertion", "d": ["The modification of an RNA molecule by insertion of a guanosine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071878", "l": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045002", "l": "double-strand break repair via single-strand annealing", "d": ["Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904635", "l": "positive regulation of podocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0098742", "l": "cell-cell adhesion via plasma-membrane adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048910", "l": "afferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051084", "l": "'de novo' post-translational protein folding", "d": ["The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905062", "l": "positive regulation of cardioblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019486", "l": "beta-alanine catabolic process to mevalonate semialdehyde, by transamination", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904526", "l": "regulation of microtubule binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0001581", "l": "detection of chemical stimulus involved in sensory perception of sour taste", "d": ["The series of events required for a sour taste stimulus to be received and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034255", "l": "regulation of urea metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904136", "l": "regulation of convergent extension involved in notochord morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034184", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.866957504416824", "identifiers": [{"i": "GO:0072001", "l": "renal system development", "d": ["The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061305", "l": "maintenance of bipolar cell polarity regulating cell shape", "d": ["The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007445", "l": "determination of imaginal disc primordium", "d": ["Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002100", "l": "tRNA wobble adenosine to inosine editing", "d": ["The process in which an adenosine in position 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process", "d": ["The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001195", "l": "maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0052646", "l": "alditol phosphate metabolic process", "d": ["The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900747", "l": "negative regulation of vascular endothelial growth factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062038", "l": "positive regulation of pheromone response MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000734", "l": "negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003250", "l": "regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901834", "l": "regulation of deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0008090", "l": "retrograde axonal transport", "d": ["The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900396", "l": "positive regulation of kojic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000335", "l": "regulation of endothelial microparticle formation", "d": ["Any process that modulates the frequency, rate or extent of endothelial microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001937", "l": "negative regulation of endothelial cell proliferation", "d": ["Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002408", "l": "myeloid dendritic cell chemotaxis", "d": ["The movement of a myeloid dendritic cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901848", "l": "nicotinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0002089", "l": "lens morphogenesis in camera-type eye", "d": ["The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904307", "l": "response to desipramine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001093", "l": "galactotriose transport", "d": ["The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003188", "l": "heart valve formation", "d": ["The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044658", "l": "pore formation in host plasma membrane", "d": ["The disruption of host plasma membrane integrity by formation of a pore, resulting in deregulated ion homeostasis, and cellular dysfunction that can result in cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070779", "l": "D-aspartate import across plasma membrane", "d": ["The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019877", "l": "diaminopimelate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900731", "l": "positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042367", "l": "biotin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001797", "l": "negative regulation of type IIa hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1902407", "l": "assembly of actomyosin apparatus involved in mitotic cytokinesis", "d": ["Any assembly of mitotic cytokinetic actomyosin apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072174", "l": "metanephric tubule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0017121", "l": "plasma membrane phospholipid scrambling", "d": ["The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904346", "l": "positive regulation of gastric mucosal blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903760", "l": "regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090252", "l": "epithelium migration involved in imaginal disc-derived wing morphogenesis", "d": ["The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072060", "l": "outer medullary collecting duct development", "d": ["The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030862", "l": "positive regulation of polarized epithelial cell differentiation", "d": ["Any process that activates or increases the rate or extent of polarized epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061328", "l": "posterior Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072177", "l": "mesonephric duct development", "d": ["The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019990", "l": "pteridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051574", "l": "positive regulation of histone H3-K9 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009104", "l": "lipopolysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021712", "l": "candelabrum cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045614", "l": "negative regulation of plasmatocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072076", "l": "nephrogenic mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000963", "l": "regulation of cellooligosaccharide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150079", "l": "negative regulation of neuroinflammatory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900544", "l": "positive regulation of purine nucleotide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901272", "l": "2-dehydro-3-deoxy-D-gluconic acid metabolic process", "d": ["The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032220", "l": "plasma membrane fusion involved in cytogamy", "d": ["The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009194", "l": "pyrimidine ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905231", "l": "cellular response to borneol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060998", "l": "regulation of dendritic spine development", "d": ["Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0051300", "l": "spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). 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This process results in the oriented division of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046203", "l": "spermidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042845", "l": "glycol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905198", "l": "manchette assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a manchette."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903925", "l": "response to bisphenol A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002499", "l": "proteolysis within endosome associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071205", "l": "protein localization to juxtaparanode region of axon", "d": ["Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090088", "l": "regulation of oligopeptide transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902935", "l": "protein localization to septin ring", "d": ["A process in which a protein is transported to, or maintained in, a location within a septin ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061698", "l": "protein deglutarylation", "d": ["The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0060147", "l": "regulation of post-transcriptional gene silencing", "d": ["Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160052", "l": "mitotic nuclear envelope segregation", "d": ["The mitotic cell cycle process in which the nuclear envelope, including nuclear pores, is equally distributed to the two daughter cells during the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0033058", "l": "directional locomotion", "d": ["Self-propelled movement of a cell or organism from one location to another along an axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046892", "l": "peptidyl-S-carbamoyl-L-cysteine dehydration", "d": ["The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035981", "l": "tongue muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051476", "l": "phosphoenolpyruvate-dependent mannosylglycerate phosphotransferase system", "d": ["A phosphoenolpyruvate-dependent sugar phosphotransferase transport specific for mammosylglycerate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071772", "l": "response to BMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080191", "l": "secondary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903121", "l": "regulation of TRAIL-activated apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000610", "l": "negative regulation of thyroid hormone generation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902231", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900125", "l": "regulation of hyaluronan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046322", "l": "negative regulation of fatty acid oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.164307912167025", "identifiers": [{"i": "GO:1901565", "l": "organonitrogen compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organonitrogen compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0002883", "l": "regulation of hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1905145", "l": "cellular response to acetylcholine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0070293", "l": "renal absorption", "d": ["A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001074", "l": "regulation of metanephric ureteric bud development", "d": ["Any process that modulates the frequency, rate or extent of metanephric ureteric bud development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000184", "l": "positive regulation of progesterone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098828", "l": "modulation of inhibitory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097198", "l": "histone H3-K36 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902724", "l": "positive regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0051354", "l": "negative regulation of oxidoreductase activity", "d": ["Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002635", "l": "negative regulation of germinal center formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061364", "l": "apoptotic process involved in luteolysis", "d": ["The apoptotic process that contributes to luteolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019858", "l": "cytosine metabolic process", "d": ["The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019555", "l": "glutamate catabolic process to ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.710521892834109", "identifiers": [{"i": "GO:0016573", "l": "histone acetylation", "d": ["The modification of a histone by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.164784581475494", "identifiers": [{"i": "GO:0006355", "l": "regulation of DNA-templated transcription", "d": ["Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.736668988739432", "identifiers": [{"i": "GO:0043043", "l": "peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0060119", "l": "inner ear receptor cell development", "d": ["The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.281072631542173", "identifiers": [{"i": "GO:0007276", "l": "gamete generation", "d": ["The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0080050", "l": "regulation of seed development", "d": ["Any process that modulates the frequency, rate or extent of seed development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106111", "l": "regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000740", "l": "negative regulation of mesenchymal stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009128", "l": "purine nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034444", "l": "regulation of plasma lipoprotein oxidation", "d": ["Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0009267", "l": "cellular response to starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032206", "l": "positive regulation of telomere maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:1903531", "l": "negative regulation of secretion by cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071910", "l": "determination of liver left/right asymmetry", "d": ["Determination of the asymmetric location of the liver with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0009078", "l": "pyruvate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:2000177", "l": "regulation of neural precursor cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of neural precursor cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140623", "l": "type I pilus assembly", "d": ["The assembly from its constituent parts of a type I pilus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009779", "l": "noncyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990194", "l": "cytoplasmic U snRNP body assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0014015", "l": "positive regulation of gliogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051281", "l": "positive regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006533", "l": "aspartate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0071470", "l": "cellular response to osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903109", "l": "positive regulation of mitochondrial transcription", "d": ["Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035819", "l": "positive regulation of renal sodium excretion by pressure natriuresis", "d": ["An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097118", "l": "neuroligin clustering involved in postsynaptic membrane assembly", "d": ["The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034139", "l": "regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042783", "l": "evasion of host immune response", "d": ["A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0050686", "l": "negative regulation of mRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032263", "l": "GMP salvage", "d": ["Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034633", "l": "retinol transport", "d": ["The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990852", "l": "protein transport along microtubule to spindle pole body", "d": ["The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043387", "l": "mycotoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048530", "l": "fruit morphogenesis", "d": ["The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050970", "l": "detection of electrical stimulus involved in magnetoreception", "d": ["The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0021515", "l": "cell differentiation in spinal cord", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015963", "l": "diadenosine triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904187", "l": "regulation of transformation of host cell by virus", "d": ["Any process that modulates the frequency, rate or extent of transformation of host cell by virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006362", "l": "transcription elongation by RNA polymerase I", "d": ["The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900364", "l": "negative regulation of mRNA polyadenylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021932", "l": "hindbrain radial glia guided cell migration", "d": ["The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070488", "l": "neutrophil aggregation", "d": ["The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002117", "l": "amphibian larval development", "d": ["The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071240", "l": "cellular response to food", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009900", "l": "dehiscence", "d": ["The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021744", "l": "dorsal motor nucleus of vagus nerve development", "d": ["The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098987", "l": "regulation of modification of synapse structure, modulating synaptic transmission", "d": ["Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001042", "l": "negative regulation of septum digestion after cytokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035212", "l": "cell competition in a multicellular organism", "d": ["Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000086", "l": "positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:1905952", "l": "regulation of lipid localization", "d": ["Any process that modulates the frequency, rate or extent of lipid localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0007190", "l": "activation of adenylate cyclase activity", "d": ["Any process that initiates the activity of the inactive enzyme adenylate cyclase."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045840", "l": "positive regulation of mitotic nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003034", "l": "detection of increased carbon dioxide by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000720", "l": "pyrimidine dimer repair by nucleotide-excision repair", "d": ["The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099646", "l": "neurotransmitter receptor transport, plasma membrane to endosome", "d": ["Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009214", "l": "cyclic nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009171", "l": "purine deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.031705934574305", "identifiers": [{"i": "GO:0003333", "l": "amino acid transmembrane transport", "d": ["The process in which an amino acid is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046298", "l": "2,4-dichlorobenzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901223", "l": "negative regulation of non-canonical NF-kappaB signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900690", "l": "negative regulation of gliotoxin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021800", "l": "cerebral cortex tangential migration", "d": ["The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070986", "l": "left/right axis specification", "d": ["The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140447", "l": "cytokine precursor processing", "d": ["The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052102", "l": "positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140655", "l": "mitochondrial proliferation", "d": ["The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042337", "l": "cuticle development involved in chitin-based cuticle molting cycle", "d": ["The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009660", "l": "amyloplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900520", "l": "positive regulation of response to pullulan", "d": ["Any process that activates or increases the frequency, rate or extent of response to pullulan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033322", "l": "homomethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048922", "l": "posterior lateral line neuromast deposition", "d": ["The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050799", "l": "cocaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.642706635493056", "identifiers": [{"i": "GO:0010608", "l": "post-transcriptional regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0007164", "l": "establishment of tissue polarity", "d": ["Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045780", "l": "positive regulation of bone resorption", "d": ["Any process that activates or increases the frequency, rate or extent of bone resorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045469", "l": "negative regulation of R8 cell spacing in compound eye", "d": ["Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0043488", "l": "regulation of mRNA stability", "d": ["Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0070585", "l": "protein localization to mitochondrion", "d": ["A process in which a protein is transported to, or maintained in, a location within the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901958", "l": "negative regulation of cutin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904496", "l": "positive regulation of substance P secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021813", "l": "cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration", "d": ["The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901629", "l": "regulation of presynaptic membrane organization", "d": ["Any process that modulates the frequency, rate or extent of presynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900143", "l": "positive regulation of oligodendrocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010996", "l": "response to auditory stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000487", "l": "positive regulation of glutamine transport", "d": ["Any process that activates or increases the frequency, rate or extent of glutamine transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048890", "l": "lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900834", "l": "regulation of emericellin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emericellin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034488", "l": "basic amino acid transmembrane export from vacuole", "d": ["The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905306", "l": "positive regulation of cardiac myofibril assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033487", "l": "pelargonidin 3-O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015996", "l": "chlorophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061824", "l": "cytosolic ciliogenesis", "d": ["The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042368", "l": "vitamin D biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0061615", "l": "glycolytic process through fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007449", "l": "proximal/distal pattern formation, imaginal disc", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048171", "l": "negative regulation of long-term neuronal synaptic plasticity", "d": ["A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903477", "l": "mitotic contractile ring actin filament bundle assembly", "d": ["Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900954", "l": "negative regulation of 18-methylnonadec-1-ene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904936", "l": "interneuron migration", "d": ["The orderly movement of an interneuron from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002614", "l": "negative regulation of monocyte antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042332", "l": "gravitaxis", "d": ["The directed movement of a motile cell or organism in response to gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1902435", "l": "regulation of male mating behavior", "d": ["Any process that modulates the frequency, rate or extent of male mating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045682", "l": "regulation of epidermis development", "d": ["Any process that modulates the frequency, rate or extent of epidermis development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021615", "l": "glossopharyngeal nerve morphogenesis", "d": ["The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:2001233", "l": "regulation of apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035699", "l": "T-helper 17 cell extravasation", "d": ["The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905514", "l": "positive regulation of short-term synaptic potentiation", "d": ["Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902077", "l": "negative regulation of lateral motor column neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0009664", "l": "plant-type cell wall organization", "d": ["A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043354", "l": "enucleate erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903495", "l": "cellular response to dehydroepiandrosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0110057", "l": "regulation of blood vessel endothelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0007379", "l": "segment specification", "d": ["The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048636", "l": "positive regulation of muscle organ development", "d": ["Any process that activates, maintains or increases the rate of muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007483", "l": "genital disc morphogenesis", "d": ["The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051572", "l": "negative regulation of histone H3-K4 methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032355", "l": "response to estradiol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0005983", "l": "starch catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021837", "l": "motogenic signaling involved in postnatal olfactory bulb interneuron migration", "d": ["The signaling that results in the stimulation of cell movement in the rostral migratory stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905464", "l": "positive regulation of DNA duplex unwinding", "d": ["Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036108", "l": "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045345", "l": "positive regulation of MHC class I biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030885", "l": "regulation of myeloid dendritic cell activation", "d": ["Any process that modulates the frequency or rate of myeloid dendritic cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:1900908", "l": "regulation of olefin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of olefin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048058", "l": "compound eye corneal lens development", "d": ["The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051791", "l": "medium-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a medium-chain fatty acid, a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006542", "l": "glutamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000049", "l": "positive regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071289", "l": "cellular response to nickel ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048080", "l": "negative regulation of cuticle pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904054", "l": "regulation of cholangiocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of cholangiocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016559", "l": "peroxisome fission", "d": ["The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900516", "l": "negative regulation of xylose catabolic process to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061262", "l": "mesonephric renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097753", "l": "membrane bending", "d": ["A membrane organization process resulting in the bending of a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008359", "l": "regulation of bicoid mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006651", "l": "diacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051191", "l": "prosthetic group biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001519", "l": "peptide amidation", "d": ["The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060848", "l": "endothelial cell fate determination", "d": ["A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140301", "l": "pollen-stigma interaction", "d": ["The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099047", "l": "clearance of foreign intracellular RNA", "d": ["A defense process that protects an organism from invading foreign RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060656", "l": "regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033479", "l": "UDP-D-galacturonate metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904810", "l": "negative regulation of dense core granule transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000241", "l": "diakinesis", "d": ["The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0051325", "l": "interphase", "d": ["The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900572", "l": "diorcinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diorcinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000323", "l": "negative regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904242", "l": "regulation of pancreatic trypsinogen secretion", "d": ["Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002810", "l": "regulation of antifungal peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060524", "l": "dichotomous subdivision of prostate epithelial cord terminal unit", "d": ["The process in which a prostate epithelial cord bifurcates at its end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042630", "l": "behavioral response to water deprivation", "d": ["Any process that results in a change in the behavior of an organism as a result of deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.271170648665588", "identifiers": [{"i": "GO:0006417", "l": "regulation of translation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905912", "l": "regulation of calcium ion export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000528", "l": "negative regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060052", "l": "neurofilament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021819", "l": "layer formation in cerebral cortex", "d": ["The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062000", "l": "positive regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902602", "l": "aluminum ion transmembrane transport", "d": ["The process in which an aluminium ion is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0071560", "l": "cellular response to transforming growth factor beta stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1901569", "l": "fatty acid derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fatty acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022005", "l": "midbrain-hindbrain boundary maturation during neural plate development", "d": ["A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001554", "l": "luteolysis", "d": ["The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019296", "l": "coenzyme M metabolic process", "d": ["The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007490", "l": "tergite morphogenesis", "d": ["The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015904", "l": "tetracycline transmembrane transport", "d": ["The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990936", "l": "vascular associated smooth muscle cell dedifferentiation", "d": ["The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090298", "l": "negative regulation of mitochondrial DNA replication", "d": ["Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904215", "l": "regulation of protein import into chloroplast stroma", "d": ["Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0042401", "l": "biogenic amine biosynthetic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070965", "l": "positive regulation of neutrophil mediated killing of fungus", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903946", "l": "negative regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000390", "l": "negative regulation of neutrophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904689", "l": "negative regulation of cytoplasmic translational initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009092", "l": "homoserine metabolic process", "d": ["The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0140962", "l": "multicellular organismal-level chemical homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042191", "l": "methylmercury metabolic process", "d": ["The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900486", "l": "positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903556", "l": "negative regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043243", "l": "positive regulation of protein-containing complex disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006853", "l": "carnitine shuttle", "d": ["The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003037", "l": "detection of pH by carotid body chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071418", "l": "cellular response to amine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990968", "l": "modulation by host of RNA binding by virus", "d": ["A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048790", "l": "maintenance of presynaptic active zone structure", "d": ["A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021878", "l": "forebrain astrocyte fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010712", "l": "regulation of collagen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036160", "l": "melanocyte-stimulating hormone secretion", "d": ["The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0120187", "l": "positive regulation of protein localization to chromatin", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0044406", "l": "adhesion of symbiont to host", "d": ["The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903493", "l": "response to clopidogrel", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061441", "l": "renal artery morphogenesis", "d": ["The process in which the anatomical structure of a renal artery is generated and organized. 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It is a cerebral stimulant and narcotic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002232", "l": "leukocyte chemotaxis involved in inflammatory response", "d": ["The movement of an immune cell in response to an external stimulus contributing to an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021703", "l": "locus ceruleus development", "d": ["The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034269", "l": "discadenine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048911", "l": "efferent axon development in anterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050889", "l": "determination of stimulus intensity", "d": ["The determination of the perceived strength of a sensory stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903604", "l": "cytochrome metabolic process", "d": ["The chemical reactions and pathways involving a cytochrome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061358", "l": "negative regulation of Wnt protein secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010244", "l": "response to low fluence blue light stimulus by blue low-fluence system", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010258", "l": "NADH dehydrogenase complex (plastoquinone) assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048100", "l": "wing disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904460", "l": "positive regulation of substance P secretion", "d": ["Any process that activates or increases the frequency, rate or extent of substance P secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0008053", "l": "mitochondrial fusion", "d": ["Merging of two or more mitochondria within a cell to form a single compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032472", "l": "Golgi calcium ion transport", "d": ["The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901737", "l": "(R)-mevalonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046620", "l": "regulation of organ growth", "d": ["Any process that modulates the frequency, rate or extent of growth of an organ of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0009064", "l": "glutamine family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002893", "l": "negative regulation of type II hypersensitivity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:1901264", "l": "carbohydrate derivative transport", "d": ["The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035813", "l": "regulation of renal sodium excretion", "d": ["Any process that modulates the amount of sodium excreted in urine over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034514", "l": "mitochondrial unfolded protein response", "d": ["The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.390126070323255", "identifiers": [{"i": "GO:0006869", "l": "lipid transport", "d": ["The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.368095522595297", "identifiers": [{"i": "GO:0016072", "l": "rRNA metabolic process", "d": ["The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001836", "l": "release of cytochrome c from mitochondria", "d": ["The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061192", "l": "negative regulation of vacuole fusion, non-autophagic", "d": ["Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990880", "l": "cellular detoxification of copper ion", "d": ["Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023002", "l": "nuclear migration to embryo sac poles", "d": ["Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905316", "l": "superior endocardial cushion morphogenesis", "d": ["The developmental process by which a superior endocardial cushion is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009172", "l": "purine deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060534", "l": "trachea cartilage development", "d": ["The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090391", "l": "granum assembly", "d": ["A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903021", "l": "regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands", "d": ["Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904675", "l": "regulation of somatic stem cell division", "d": ["Any process that modulates the frequency, rate or extent of somatic stem cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901831", "l": "all-trans-neoxanthin metabolic process", "d": ["The chemical reactions and pathways involving all-trans-neoxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904598", "l": "positive regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that activates or increases the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035709", "l": "memory T cell activation", "d": ["The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033337", "l": "dorsal fin development", "d": ["The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002267", "l": "follicular dendritic cell activation involved in immune response", "d": ["A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018287", "l": "iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide", "d": ["The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060379", "l": "cardiac muscle cell myoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901458", "l": "negative regulation of response to acetate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0051960", "l": "regulation of nervous system development", "d": ["Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002864", "l": "regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072318", "l": "clathrin coat disassembly", "d": ["The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071210", "l": "protein insertion into membrane raft", "d": ["The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106113", "l": "positive regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001232", "l": "positive regulation of protein localization to prospore membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048527", "l": "lateral root development", "d": ["The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046678", "l": "response to bacteriocin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905336", "l": "negative regulation of aggrephagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050925", "l": "negative regulation of negative chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061118", "l": "regulation of positive chemotaxis to cAMP", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0022612", "l": "gland morphogenesis", "d": ["The process in which the anatomical structures of a gland are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035090", "l": "maintenance of apical/basal cell polarity", "d": ["Retaining the established polarization of a cell along its apical/basal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0086026", "l": "atrial cardiac muscle cell to AV node cell signaling", "d": ["Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072052", "l": "juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002479", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0086048", "l": "membrane depolarization during bundle of His cell action potential", "d": ["The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1902778", "l": "response to alkane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000120", "l": "positive regulation of sodium-dependent phosphate transport", "d": ["Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001905", "l": "activation of membrane attack complex", "d": ["The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045602", "l": "negative regulation of endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045110", "l": "intermediate filament bundle assembly", "d": ["The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0046546", "l": "development of primary male sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061194", "l": "taste bud morphogenesis", "d": ["The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033494", "l": "ferulate metabolic process", "d": ["The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905184", "l": "positive regulation of protein serine/threonine phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0043575", "l": "detection of osmotic stimulus", "d": ["The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070096", "l": "mitochondrial outer membrane translocase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003199", "l": "endocardial cushion to mesenchymal transition involved in heart valve formation", "d": ["A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140572", "l": "vacuole fission", "d": ["The division of a vacuole within a cell to form two or more separate vacuoles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106216", "l": "positive regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046196", "l": "4-nitrophenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043249", "l": "erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090617", "l": "mitochondrial mRNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.836170798622533", "identifiers": [{"i": "GO:0006486", "l": "protein glycosylation", "d": ["A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0003044", "l": "regulation of systemic arterial blood pressure mediated by a chemical signal", "d": ["The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.519625387257847", "identifiers": [{"i": "GO:0006401", "l": "RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039678", "l": "viral genome ejection through host cell envelope", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902629", "l": "regulation of mRNA stability involved in cellular response to UV", "d": ["Any regulation of mRNA stability that is involved in cellular response to UV."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051160", "l": "L-xylitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150101", "l": "regulation of microtubule anchoring at centrosome", "d": ["Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0022410", "l": "circadian sleep/wake cycle process", "d": ["A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900551", "l": "N',N'',N'''-triacetylfusarinine C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0052546", "l": "cell wall pectin metabolic process", "d": ["The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050652", "l": "dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002101", "l": "tRNA wobble cytosine modification", "d": ["The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061453", "l": "interstitial cell of Cajal differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901717", "l": "positive regulation of gamma-aminobutyric acid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035846", "l": "oviduct epithelium development", "d": ["The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099082", "l": "retrograde trans-synaptic signaling by neuropeptide", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045648", "l": "positive regulation of erythrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0099550", "l": "trans-synaptic signaling, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051886", "l": "negative regulation of timing of anagen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902942", "l": "negative regulation of voltage-gated chloride channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902280", "l": "regulation of RNA helicase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048161", "l": "double layer follicle stage", "d": ["The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046492", "l": "heme B metabolic process", "d": ["The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002611", "l": "negative regulation of plasmacytoid dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0006022", "l": "aminoglycan metabolic process", "d": ["The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902727", "l": "negative regulation of growth factor dependent skeletal muscle satellite cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000432", "l": "negative regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.365551207689407", "identifiers": [{"i": "GO:1903311", "l": "regulation of mRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of mRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141068", "l": "autosome genomic imprinting", "d": ["The establishment of epigenetic modifications (imprints) in autosomal (non-sexual) chromosomes during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018062", "l": "peptidyl-tryptophan succinylation", "d": ["The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901286", "l": "iron-sulfur-molybdenum cofactor metabolic process", "d": ["The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903578", "l": "regulation of ATP metabolic process", "d": ["Any process that modulates the frequency, rate or extent of ATP metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.792968087059343", "identifiers": [{"i": "GO:0002521", "l": "leukocyte differentiation", "d": ["The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905378", "l": "cellular response to D-galactose", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009182", "l": "purine deoxyribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0006998", "l": "nuclear envelope organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140210", "l": "protein transport along microtubule to kinetochore", "d": ["Any process in which a protein is transported to the kinetochore along a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905074", "l": "negative regulation of tight junction disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000985", "l": "positive regulation of ATP citrate synthase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090282", "l": "positive regulation of transcription involved in G2/M transition of mitotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000218", "l": "negative regulation of invasive growth in response to glucose limitation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902823", "l": "negative regulation of late endosome to lysosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080148", "l": "negative regulation of response to water deprivation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006540", "l": "glutamate decarboxylation to succinate", "d": ["The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900781", "l": "fumiquinazoline C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035228", "l": "negative regulation of glutamate-cysteine ligase activity", "d": ["Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:1903039", "l": "positive regulation of leukocyte cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0062042", "l": "regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021965", "l": "spinal cord ventral commissure morphogenesis", "d": ["The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900737", "l": "negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0050870", "l": "positive regulation of T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045779", "l": "negative regulation of bone resorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072326", "l": "vulval cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034696", "l": "response to prostaglandin F", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000509", "l": "negative regulation of dendritic cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002567", "l": "somatic diversification of FREP-based immune receptors", "d": ["The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021649", "l": "vestibulocochlear nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033628", "l": "regulation of cell adhesion mediated by integrin", "d": ["Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046605", "l": "regulation of centrosome cycle", "d": ["Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901435", "l": "negative regulation of toluene catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018221", "l": "peptidyl-serine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048694", "l": "positive regulation of collateral sprouting of injured axon", "d": ["Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0043379", "l": "memory T cell differentiation", "d": ["The process in which a newly activated T cell acquires specialized features of a memory T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905008", "l": "regulation of L-lysine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-lysine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.632645734840118", "identifiers": [{"i": "GO:0048869", "l": "cellular developmental process", "d": ["A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070863", "l": "positive regulation of protein exit from endoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003210", "l": "cardiac atrium formation", "d": ["The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0150137", "l": "interleukin-37 production", "d": ["The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990632", "l": "branching involved in submandibular gland morphogenesis", "d": ["The process in which the branching structure of the submandibular gland is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006370", "l": "7-methylguanosine mRNA capping", "d": ["Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0099173", "l": "postsynapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051934", "l": "catecholamine uptake involved in synaptic transmission", "d": ["The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030207", "l": "chondroitin sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901806", "l": "beta-glucoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904668", "l": "positive regulation of ubiquitin protein ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099187", "l": "presynaptic cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032378", "l": "negative regulation of intracellular lipid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0005979", "l": "regulation of glycogen biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070941", "l": "eisosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046391", "l": "5-phosphoribose 1-diphosphate metabolic process", "d": ["The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905546", "l": "cellular response to phenylpropanoid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072251", "l": "metanephric juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0033048", "l": "negative regulation of mitotic sister chromatid segregation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140876", "l": "andrastin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905523", "l": "positive regulation of macrophage migration", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0015801", "l": "aromatic amino acid transport", "d": ["The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900304", "l": "negative regulation of laminaritriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038020", "l": "insulin receptor recycling", "d": ["The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046280", "l": "chalcone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014823", "l": "response to activity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071690", "l": "cardiac muscle myosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0018393", "l": "internal peptidyl-lysine acetylation", "d": ["The addition of an acetyl group to a non-terminal lysine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0051952", "l": "regulation of amine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990670", "l": "vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071311", "l": "cellular response to acetate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0015959", "l": "diadenosine polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045775", "l": "positive regulation of beta 2 integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048895", "l": "lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901330", "l": "negative regulation of odontoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0045190", "l": "isotype switching", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030278", "l": "regulation of ossification", "d": ["Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046089", "l": "cytosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901518", "l": "aspyridone A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspyridone A."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0050871", "l": "positive regulation of B cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0099118", "l": "microtubule-based protein transport", "d": ["A microtubule-based process that results in the transport of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035356", "l": "intracellular triglyceride homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035876", "l": "maintenance of meiotic sister chromatid cohesion, arms", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009293", "l": "transduction", "d": ["A type of horizontal gene transfer in which genetic material is introduced into a cell mediated by a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014057", "l": "positive regulation of acetylcholine secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099137", "l": "altruistic, chimeric, non-reproductive fruiting body development", "d": ["Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070660", "l": "inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration", "d": ["Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010747", "l": "positive regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072595", "l": "maintenance of protein localization in organelle", "d": ["Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000066", "l": "positive regulation of cortisol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070101", "l": "positive regulation of chemokine-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010555", "l": "response to mannitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044346", "l": "fibroblast apoptotic process", "d": ["Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009661", "l": "chromoplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046283", "l": "anthocyanin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035227", "l": "regulation of glutamate-cysteine ligase activity", "d": ["Any process that modulates the activity of glutamate-cysteine ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902263", "l": "apoptotic process involved in embryonic digit morphogenesis", "d": ["Any apoptotic process that is involved in embryonic digit morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052543", "l": "callose deposition in cell wall", "d": ["Any process in which callose is transported to, and/or maintained in, the cell wall. 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The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140889", "l": "DNA replication-dependent chromatin disassembly", "d": ["The disruption of nucleosomes during DNA replication to allow the replication machinery to access the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902439", "l": "cellular response to vanadate(3-)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0019062", "l": "virion attachment to host cell", "d": ["The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048343", "l": "paraxial mesodermal cell fate commitment", "d": ["The process in which a cell becomes committed to become a paraxial mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071421", "l": "manganese ion transmembrane transport", "d": ["A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.728321745325424", "identifiers": [{"i": "GO:0071695", "l": "anatomical structure maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019736", "l": "peptidyl-sarcosine incorporation", "d": ["The incorporation of sarcosine (N-methylglycine) into non-coded peptides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042381", "l": "hemolymph coagulation", "d": ["Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0007005", "l": "mitochondrion organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060494", "l": "inductive mesenchymal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048401", "l": "negative regulation of intermediate mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901289", "l": "succinyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021512", "l": "spinal cord anterior/posterior patterning", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0043050", "l": "pharyngeal pumping", "d": ["The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900871", "l": "chloroplast mRNA modification", "d": ["The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901114", "l": "erythromycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of erythromycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050495", "l": "peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903426", "l": "regulation of reactive oxygen species biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036018", "l": "cellular response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019756", "l": "cyanogenic glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0048193", "l": "Golgi vesicle transport", "d": ["The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043973", "l": "histone H3-K4 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014062", "l": "regulation of serotonin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of serotonin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000476", "l": "maturation of 4.5S rRNA", "d": ["Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035096", "l": "larval midgut cell programmed cell death", "d": ["The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098786", "l": "biofilm matrix disassembly", "d": ["A process that results in the disassembly of a biofilm matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034640", "l": "establishment of mitochondrion localization by microtubule attachment", "d": ["The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021780", "l": "glial cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032670", "l": "regulation of interleukin-26 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-26 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046386", "l": "deoxyribose phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904258", "l": "nuclear dicing body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0003231", "l": "cardiac ventricle development", "d": ["The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. 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Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903422", "l": "negative regulation of synaptic vesicle recycling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000969", "l": "positive regulation of AMPA receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021926", "l": "Golgi cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904040", "l": "positive regulation of iron export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.24517279685756", "identifiers": [{"i": "GO:0017145", "l": "stem cell division", "d": ["The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0030834", "l": "regulation of actin filament depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904884", "l": "positive regulation of telomerase catalytic core complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070408", "l": "carbamoyl phosphate metabolic process", "d": ["The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905917", "l": "positive regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905453", "l": "regulation of myeloid progenitor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900636", "l": "heptadecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heptadecane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039692", "l": "single stranded viral RNA replication via double stranded DNA intermediate", "d": ["A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904833", "l": "positive regulation of removal of superoxide radicals", "d": ["Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902784", "l": "response to undecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046397", "l": "galacturonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010111", "l": "glyoxysome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018887", "l": "4-carboxy-4'-sulfoazobenzene metabolic process", "d": ["The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071610", "l": "chemokine (C-C motif) ligand 1 production", "d": ["The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006581", "l": "acetylcholine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060413", "l": "atrial septum morphogenesis", "d": ["The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036285", "l": "SAGA complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062166", "l": "negative regulation of pseudohyphal septin ring assembly", "d": ["Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000254", "l": "regulation of male germ cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of male germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045033", "l": "peroxisome inheritance", "d": ["The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002428", "l": "antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0042730", "l": "fibrinolysis", "d": ["A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019462", "l": "glutamine catabolic process to fumarate, using glutaminase", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003304", "l": "myocardial epithelial involution involved in heart jogging", "d": ["The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1903306", "l": "negative regulation of regulated secretory pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060967", "l": "negative regulation of gene silencing by regulatory ncRNA", "d": ["Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023059", "l": "positive adaptation of signaling pathway", "d": ["The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0098781", "l": "ncRNA transcription", "d": ["The transcription of non (protein) coding RNA from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903950", "l": "negative regulation of AV node cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043969", "l": "histone H2B acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046719", "l": "regulation by virus of viral protein levels in host cell", "d": ["Any virus-mediated process that modulates the levels of viral proteins in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045915", "l": "positive regulation of catecholamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006098", "l": "pentose-phosphate shunt", "d": ["The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0018904", "l": "ether metabolic process", "d": ["The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905424", "l": "regulation of Wnt-mediated midbrain dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007434", "l": "adult salivary gland boundary specification", "d": ["Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072231", "l": "metanephric proximal convoluted tubule segment 1 development", "d": ["The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009167", "l": "purine ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035344", "l": "hypoxanthine transport", "d": ["The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902920", "l": "poly(hydroxyvalerate) metabolic process", "d": ["The chemical reactions and pathways involving poly(hydroxyvalerate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021520", "l": "spinal cord motor neuron cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090360", "l": "platelet-derived growth factor production", "d": ["The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003351", "l": "epithelial cilium movement involved in extracellular fluid movement", "d": ["The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035149", "l": "lumen formation, open tracheal system", "d": ["Creation of the central hole of a tube in an open tracheal system through which gases flow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048692", "l": "negative regulation of axon extension involved in regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042137", "l": "sequestering of neurotransmitter", "d": ["The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002043", "l": "blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043309", "l": "regulation of eosinophil degranulation", "d": ["Any process that modulates the frequency, rate, or extent of eosinophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031637", "l": "regulation of neuronal synaptic plasticity in response to neurotrophin", "d": ["The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036153", "l": "triglyceride acyl-chain remodeling", "d": ["Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.37651133774304", "identifiers": [{"i": "GO:0018022", "l": "peptidyl-lysine methylation", "d": ["The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902838", "l": "regulation of nuclear migration along microtubule", "d": ["Any process that modulates the frequency, rate or extent of nuclear migration along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003277", "l": "apoptotic process involved in endocardial cushion morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of an endocardial cushion. 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Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048686", "l": "regulation of sprouting of injured axon", "d": ["Any process that modulates the frequency, rate or extent of sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071766", "l": "Actinobacterium-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002913", "l": "positive regulation of lymphocyte anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051729", "l": "germline cell cycle switching, mitotic to meiotic cell cycle", "d": ["The process in which a germline cell switches cell cycle mode from mitotic to meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033342", "l": "negative regulation of collagen binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042707", "l": "ocellus photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070781", "l": "response to biotin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046016", "l": "positive regulation of transcription by glucose", "d": ["Any process involving glucose that activates or increases the rate of transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014061", "l": "regulation of norepinephrine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021979", "l": "hypothalamus cell differentiation", "d": ["The differentiation of cells that will contribute to the structure and function of the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003310", "l": "pancreatic A cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. 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A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046333", "l": "octopamine metabolic process", "d": ["The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0036315", "l": "cellular response to sterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0003416", "l": "endochondral bone growth", "d": ["The increase in size or mass of an endochondral bone that contributes to the shaping of the bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905242", "l": "response to 3,3',5-triiodo-L-thyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000871", "l": "negative regulation of progesterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042789", "l": "mRNA transcription by RNA polymerase II", "d": ["The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043396", "l": "corticotropin-releasing hormone secretion", "d": ["The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0016120", "l": "carotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044077", "l": "modulation by symbiont of host receptor-mediated endocytosis", "d": ["The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900671", "l": "negative regulation of F-9775A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018930", "l": "3-methylquinoline metabolic process", "d": ["The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061114", "l": "branching involved in pancreas morphogenesis", "d": ["The process in which the branches of the pancreas are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0000398", "l": "mRNA splicing, via spliceosome", "d": ["The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010196", "l": "nonphotochemical quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010079", "l": "maintenance of vegetative meristem identity", "d": ["The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904010", "l": "response to Aroclor 1254", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039636", "l": "suppression by virus of host cell wall biogenesis", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017126", "l": "nucleologenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071211", "l": "protein targeting to vacuole involved in autophagy", "d": ["The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035208", "l": "positive regulation of hemocyte proliferation", "d": ["Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090504", "l": "epiboly", "d": ["The expansion of one cell sheet over other cells or yolk."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060681", "l": "branch elongation involved in ureteric bud branching", "d": ["The growth of a branch of the ureteric bud along its axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000840", "l": "regulation of dehydroepiandrosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048612", "l": "post-embryonic ectodermal digestive tract development", "d": ["The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140673", "l": "transcription elongation-coupled chromatin remodeling", "d": ["A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060380", "l": "regulation of single-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048901", "l": "anterior lateral line neuromast development", "d": ["The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072724", "l": "response to 4-nitroquinoline N-oxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033004", "l": "negative regulation of mast cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043479", "l": "pigment accumulation in tissues in response to UV light", "d": ["The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1901978", "l": "positive regulation of cell cycle checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0015874", "l": "norepinephrine transport", "d": ["The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070982", "l": "L-asparagine metabolic process", "d": ["The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060694", "l": "regulation of cholesterol transporter activity", "d": ["Any process that modulates the rate, frequency, or extent of cholesterol transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120076", "l": "negative regulation of endocardial cushion cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000713", "l": "meiotic heteroduplex formation", "d": ["During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016543", "l": "male courtship behavior, orientation prior to leg tapping and wing vibration", "d": ["The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009727", "l": "detection of ethylene stimulus", "d": ["The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090056", "l": "regulation of chlorophyll metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080121", "l": "AMP transport", "d": ["The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002108", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009763", "l": "NAD-malic enzyme C4 photosynthesis", "d": ["The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061884", "l": "regulation of mini excitatory postsynaptic potential", "d": ["Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:1903900", "l": "regulation of viral life cycle", "d": ["Any process that modulates the frequency, rate or extent of viral life cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.544026779845908", "identifiers": [{"i": "GO:0019748", "l": "secondary metabolic process", "d": ["The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008586", "l": "imaginal disc-derived wing vein morphogenesis", "d": ["The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0035891", "l": "exit from host cell", "d": ["The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033672", "l": "positive regulation of NAD+ kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000083", "l": "regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902457", "l": "negative regulation of stomatal opening", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901817", "l": "beta-zeacarotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904342", "l": "negative regulation of colon smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051977", "l": "lysophospholipid transport", "d": ["The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0042274", "l": "ribosomal small subunit biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046108", "l": "uridine metabolic process", "d": ["The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0016236", "l": "macroautophagy", "d": ["The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006968", "l": "cellular defense response", "d": ["A defense response that is mediated by cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110125", "l": "negative regulation of myotube cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0050955", "l": "thermoception", "d": ["The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002620", "l": "negative regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0015701", "l": "bicarbonate transport", "d": ["The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904558", "l": "response to dextromethorphan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010060", "l": "negative regulation of atrichoblast fate specification", "d": ["Any process that suppresses atrichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033614", "l": "chloroplast proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010143", "l": "cutin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034107", "l": "negative regulation of erythrocyte clearance", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090338", "l": "positive regulation of formin-nucleated actin cable assembly", "d": ["Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090669", "l": "telomerase RNA stabilization", "d": ["Prevention of degradation of telomerase RNA (TERC) molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071548", "l": "response to dexamethasone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048846", "l": "axon extension involved in axon guidance", "d": ["The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0009414", "l": "response to water deprivation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001845", "l": "phagolysosome assembly", "d": ["The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019549", "l": "glutamate catabolic process to succinate via succinate semialdehyde", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032460", "l": "negative regulation of protein oligomerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046705", "l": "CDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106397", "l": "positive regulation of R7 cell fate commitment", "d": ["Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060809", "l": "mesodermal to mesenchymal transition involved in gastrulation", "d": ["The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905641", "l": "cellular response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0047497", "l": "mitochondrion transport along microtubule", "d": ["The directed movement of a mitochondrion along a microtubule, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905153", "l": "regulation of membrane invagination", "d": ["Any process that modulates the frequency, rate or extent of membrane invagination."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0001738", "l": "morphogenesis of a polarized epithelium", "d": ["The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990839", "l": "response to endothelin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014030", "l": "mesenchymal cell fate commitment", "d": ["The process in which a cell becomes committed to become a mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035745", "l": "T-helper 2 cell cytokine production", "d": ["Any process that contributes to cytokine production by a T-helper 2 cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010643", "l": "cell communication by chemical coupling", "d": ["The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061203", "l": "striated muscle paramyosin thick filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016243", "l": "regulation of autophagosome size", "d": ["Any process that modulates the size of the autophagosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048932", "l": "myelination of posterior lateral line nerve axons", "d": ["The formation of compact myelin sheaths around the axons of the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904225", "l": "positive regulation of glucuronosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042636", "l": "negative regulation of hair cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030995", "l": "cell septum edging catabolic process", "d": ["The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0062044", "l": "negative regulation of cardiac epithelial to mesenchymal transition", "d": ["Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016237", "l": "lysosomal microautophagy", "d": ["The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.017691718149159", "identifiers": [{"i": "GO:0034248", "l": "regulation of amide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090169", "l": "regulation of spindle assembly", "d": ["Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043104", "l": "positive regulation of GTP cyclohydrolase I activity", "d": ["Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032087", "l": "regulation of type IV site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905864", "l": "regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901927", "l": "cadinene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cadinene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904728", "l": "positive regulation of replicative senescence", "d": ["Any process that activates or increases the frequency, rate or extent of replicative senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990751", "l": "Schwann cell chemotaxis", "d": ["The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0160062", "l": "cutin-based cuticle development", "d": ["The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. Cutin-based cuticle is an extracellular structure composed of a covalently linked macromolecular scaffold of cutin and a variety of organic solvent-soluble lipids that are collectively termed waxes. Such structures are found on the external face of polysaccharide cell walls in land plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048888", "l": "neuromast mantle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900535", "l": "palmitic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of palmitic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033539", "l": "fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.388382942757389", "identifiers": [{"i": "GO:0006664", "l": "glycolipid metabolic process", "d": ["The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035430", "l": "regulation of gluconate transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901761", "l": "oxytetracycline metabolic process", "d": ["The chemical reactions and pathways involving oxytetracycline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019428", "l": "allantoin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097330", "l": "response to 5-fluoro-2'-deoxyuridine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0098708", "l": "glucose import across plasma membrane", "d": ["The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061967", "l": "establishment of left sidedness", "d": ["The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903881", "l": "regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016545", "l": "male courtship behavior, veined wing vibration", "d": ["The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150180", "l": "negative regulation of phosphatidylserine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045943", "l": "positive regulation of transcription by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034776", "l": "response to histamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003392", "l": "cell adhesion involved in retrograde extension", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903096", "l": "protein localization to meiotic spindle midzone", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072580", "l": "bacterial-type EF-P lysine modification", "d": ["The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010470", "l": "regulation of gastrulation", "d": ["Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0001911", "l": "negative regulation of leukocyte mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031494", "l": "regulation of mating type switching", "d": ["Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048670", "l": "regulation of collateral sprouting", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061402", "l": "positive regulation of transcription from RNA polymerase II promoter in response to acidic pH", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002471", "l": "monocyte antigen processing and presentation", "d": ["The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043381", "l": "negative regulation of memory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of memory T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071230", "l": "cellular response to amino acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032704", "l": "negative regulation of interleukin-20 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903692", "l": "methionine import across plasma membrane", "d": ["The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0007034", "l": "vacuolar transport", "d": ["The directed movement of substances into, out of or within a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061930", "l": "regulation of erythrocyte enucleation", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte enucleation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0030307", "l": "positive regulation of cell growth", "d": ["Any process that activates or increases the frequency, rate, extent or direction of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061521", "l": "hepatic stellate cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0010413", "l": "glucuronoxylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048227", "l": "plasma membrane to endosome transport", "d": ["Transport of a vesicle from the plasma membrane to the endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0048638", "l": "regulation of developmental growth", "d": ["Any process that modulates the frequency, rate or extent of developmental growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031944", "l": "negative regulation of glucocorticoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033217", "l": "regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0009832", "l": "plant-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901496", "l": "positive regulation of cysteine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033506", "l": "glucosinolate biosynthetic process from homomethionine", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000793", "l": "cell proliferation involved in heart valve development", "d": ["Any cell proliferation that is involved in heart valve development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032769", "l": "negative regulation of monooxygenase activity", "d": ["Any process that stops or reduces the activity of a monooxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032616", "l": "interleukin-13 production", "d": ["The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002838", "l": "negative regulation of immune response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900869", "l": "tatiopterin metabolic process", "d": ["The chemical reactions and pathways involving tatiopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900421", "l": "positive regulation of cellular alcohol catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905288", "l": "vascular associated smooth muscle cell apoptotic process", "d": ["Any apoptotic process in a vascular associated smooth muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902222", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042413", "l": "carnitine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1902983", "l": "DNA strand elongation involved in mitotic DNA replication", "d": ["Any DNA strand elongation involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001119", "l": "protein-DNA-RNA complex remodeling", "d": ["The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001296", "l": "N(omega)-methyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega)-methyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090312", "l": "positive regulation of protein deacetylation", "d": ["Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071854", "l": "cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly", "d": ["The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010742", "l": "macrophage derived foam cell differentiation", "d": ["The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006689", "l": "ganglioside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048560", "l": "establishment of anatomical structure orientation", "d": ["The process that determines the orientation of an anatomical structure with reference to an axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033351", "l": "UDP-D-apiose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031448", "l": "positive regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021683", "l": "cerebellar granular layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900223", "l": "positive regulation of amyloid-beta clearance", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903192", "l": "sesquarterpene metabolic process", "d": ["The chemical reactions and pathways involving sesquarterpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0008611", "l": "ether lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036118", "l": "hyaluranon cable assembly", "d": ["A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097092", "l": "polyacyltrehalose metabolic process", "d": ["The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072244", "l": "metanephric glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071281", "l": "cellular response to iron ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030422", "l": "siRNA processing", "d": ["A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0000915", "l": "actomyosin contractile ring assembly", "d": ["The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990786", "l": "cellular response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903007", "l": "positive regulation of Lys63-specific deubiquitinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060580", "l": "ventral spinal cord interneuron fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903588", "l": "negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0019660", "l": "glycolytic fermentation", "d": ["Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036187", "l": "cell growth mode switching, budding to filamentous", "d": ["The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009254", "l": "peptidoglycan turnover", "d": ["The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901746", "l": "prephenate(2-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prephenate(2-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002383", "l": "immune response in brain or nervous system", "d": ["An immune response taking place in the brain or nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090505", "l": "epiboly involved in wound healing", "d": ["The expansion of one cell sheet over other cells involved in wound healing."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0060911", "l": "cardiac cell fate commitment", "d": ["The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033362", "l": "lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086050", "l": "membrane repolarization during bundle of His cell action potential", "d": ["The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904341", "l": "regulation of colon smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of colon smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019657", "l": "glycolytic fermentation to propionate", "d": ["Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097011", "l": "cellular response to granulocyte macrophage colony-stimulating factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042372", "l": "phylloquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001177", "l": "negative regulation of mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0007424", "l": "open tracheal system development", "d": ["The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034183", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902830", "l": "negative regulation of spinal cord association neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901180", "l": "spheroidene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spheroidene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001311", "l": "lysobisphosphatidic acid metabolic process", "d": ["The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072435", "l": "response to mitotic G2 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002143", "l": "tRNA wobble position uridine thiolation", "d": ["The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904898", "l": "negative regulation of hepatic stellate cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070417", "l": "cellular response to cold", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014898", "l": "cardiac muscle hypertrophy in response to stress", "d": ["The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060516", "l": "primary prostatic bud elongation", "d": ["The increase in size of the prostatic bud as it forms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036257", "l": "multivesicular body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903391", "l": "regulation of adherens junction organization", "d": ["Any process that modulates the frequency, rate or extent of adherens junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090660", "l": "cerebrospinal fluid circulation", "d": ["The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046224", "l": "bacteriocin metabolic process", "d": ["The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900510", "l": "negative regulation of pentose catabolic process to ethanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003315", "l": "heart rudiment formation", "d": ["The developmental process pertaining to the initial formation of the heart rudiment."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0034306", "l": "regulation of sexual sporulation", "d": ["Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901028", "l": "regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009786", "l": "regulation of asymmetric cell division", "d": ["Any process that modulates the frequency, rate or extent of asymmetric cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902794", "l": "siRNA-independent facultative heterochromatin formation", "d": ["The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902266", "l": "intracellular abscisic acid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of abscisic acid within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000757", "l": "negative regulation of peptidyl-lysine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035395", "l": "negative regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046884", "l": "follicle-stimulating hormone secretion", "d": ["The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903534", "l": "regulation of lactose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of lactose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022022", "l": "septal cell proliferation", "d": ["The multiplication or reproduction of septal cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001280", "l": "positive regulation of unsaturated fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050948", "l": "positive regulation of early stripe melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010987", "l": "negative regulation of high-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141033", "l": "perturbation by symbiont of host actin cytoskeleton via actin polymerization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by polymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090674", "l": "endothelial cell-matrix adhesion via fibronectin", "d": ["The binding of an endothelial cell to the extracellular matrix via fibronectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046986", "l": "negative regulation of hemoglobin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0060688", "l": "regulation of morphogenesis of a branching structure", "d": ["Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904756", "l": "negative regulation of gut granule assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046071", "l": "dGTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070811", "l": "glycerol-2-phosphate transmembrane transport", "d": ["The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035287", "l": "head segmentation", "d": ["Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090718", "l": "adaptive immune effector response", "d": ["An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033611", "l": "oxalate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0106104", "l": "regulation of glutamate receptor clustering", "d": ["Any process that modulates the frequency, rate or extent of glutamate receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051906", "l": "maintenance of pigment granule location", "d": ["Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000559", "l": "regulation of CD24 production", "d": ["Any process that modulates the frequency, rate or extent of CD24 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010575", "l": "positive regulation of vascular endothelial growth factor production", "d": ["Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018234", "l": "peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine", "d": ["The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014833", "l": "skeletal muscle satellite stem cell asymmetric division", "d": ["The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902421", "l": "hydrogen metabolic process", "d": ["The chemical reactions and pathways involving H2 (dihydrogen)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002564", "l": "alternate splicing of immunoglobulin genes", "d": ["The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019129", "l": "peptidyl-leucine racemization", "d": ["The racemization of peptidyl-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010345", "l": "suberin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001054", "l": "negative regulation of mesenchymal cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072002", "l": "Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901301", "l": "regulation of cargo loading into COPII-coated vesicle", "d": ["Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043613", "l": "isoprene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035909", "l": "aorta morphogenesis", "d": ["The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.400129184613753", "identifiers": [{"i": "GO:1901701", "l": "cellular response to oxygen-containing compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033513", "l": "L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903220", "l": "positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904461", "l": "ergosteryl 3-beta-D-glucoside metabolic process", "d": ["The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002865", "l": "negative regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046455", "l": "organosilicon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023003", "l": "nuclear migration to the embryo sac center", "d": ["Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.408607444211199", "identifiers": [{"i": "GO:0061919", "l": "process utilizing autophagic mechanism", "d": ["A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006843", "l": "mitochondrial citrate transmembrane transport", "d": ["The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901881", "l": "positive regulation of protein depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0010965", "l": "regulation of mitotic sister chromatid separation", "d": ["Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0071305", "l": "cellular response to vitamin D", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902228", "l": "positive regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0000086", "l": "G2/M transition of mitotic cell cycle", "d": ["The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0018216", "l": "peptidyl-arginine methylation", "d": ["The addition of a methyl group to an arginine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014715", "l": "myoblast fate commitment in trunk", "d": ["The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0034293", "l": "sexual sporulation", "d": ["The formation of spores derived from the products of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061725", "l": "cytosolic lipolysis", "d": ["The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035201", "l": "leg disc anterior/posterior lineage restriction", "d": ["Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0018085", "l": "peptidyl-L-amino acid racemization", "d": ["The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061036", "l": "positive regulation of cartilage development", "d": ["Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031087", "l": "deadenylation-independent decapping of nuclear-transcribed mRNA", "d": ["Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030913", "l": "paranodal junction assembly", "d": ["Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0071166", "l": "ribonucleoprotein complex localization", "d": ["Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002552", "l": "serotonin secretion by mast cell", "d": ["The regulated release of serotonin by a mast cell or group of mast cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002174", "l": "mammary stem cell proliferation", "d": ["The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045695", "l": "negative regulation of embryo sac egg cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003177", "l": "pulmonary valve development", "d": ["The progression of the pulmonary valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090218", "l": "positive regulation of lipid kinase activity", "d": ["Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070238", "l": "activated T cell autonomous cell death", "d": ["A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090332", "l": "stomatal closure", "d": ["The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030809", "l": "negative regulation of nucleotide biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902795", "l": "siRNA-mediated facultative heterochromatin formation", "d": ["The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003021", "l": "detection of increased carbon dioxide by chemoreceptor signaling", "d": ["The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150118", "l": "negative regulation of cell-substrate junction organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042432", "l": "indole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033022", "l": "cyclopentanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclopentanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0048565", "l": "digestive tract development", "d": ["The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043638", "l": "puromycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990700", "l": "nucleolar chromatin organization", "d": ["Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016270", "l": "O-glycan processing, core 4", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035630", "l": "bone mineralization involved in bone maturation", "d": ["The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905681", "l": "negative regulation of innate immunity memory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902160", "l": "negative regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060750", "l": "epithelial cell proliferation involved in mammary gland duct elongation", "d": ["The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007469", "l": "antennal development", "d": ["The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900033", "l": "negative regulation of trichome patterning", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006583", "l": "melanin biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901814", "l": "astaxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of astaxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007300", "l": "ovarian nurse cell to oocyte transport", "d": ["Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022031", "l": "telencephalon astrocyte cell migration", "d": ["The orderly movement of an astrocyte cell through the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090120", "l": "lysosome to ER cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062165", "l": "positive regulation of pseudohyphal septin ring assembly", "d": ["Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044742", "l": "envenomation resulting in modulation of sensory perception of pain in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903442", "l": "response to lipoic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019732", "l": "antifungal humoral response", "d": ["An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.617157379190189", "identifiers": [{"i": "GO:0044093", "l": "positive regulation of molecular function", "d": ["Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0042710", "l": "biofilm formation", "d": ["A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902133", "l": "(+)-secoisolariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0071025", "l": "RNA surveillance", "d": ["A process that identifies and degrades defective or aberrant RNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097714", "l": "response to viscosity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036008", "l": "sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0006687", "l": "glycosphingolipid metabolic process", "d": ["The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150144", "l": "negative regulation of CD80 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033242", "l": "negative regulation of amine catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009836", "l": "fruit ripening, climacteric", "d": ["A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045314", "l": "regulation of compound eye photoreceptor development", "d": ["Any process that modulates the frequency, rate or extent of compound eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000926", "l": "positive regulation of cellodextrin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070285", "l": "pigment cell development", "d": ["The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0072312", "l": "metanephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.245311748130447", "identifiers": [{"i": "GO:0019751", "l": "polyol metabolic process", "d": ["The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901736", "l": "(R)-mevalonic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002316", "l": "follicular B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045769", "l": "negative regulation of asymmetric cell division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "34.336622866852061", "identifiers": [{"i": "GO:0050789", "l": "regulation of biological process", "d": ["Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903017", "l": "positive regulation of exo-alpha-sialidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901195", "l": "positive regulation of formation of translation preinitiation complex", "d": ["Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036091", "l": "positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006728", "l": "pteridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000481", "l": "positive regulation of cAMP-dependent protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0017014", "l": "protein nitrosylation", "d": ["The covalent addition of a nitric oxide group to an amino acid within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075328", "l": "formation of arbuscule for nutrient acquisition", "d": ["The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090393", "l": "sepal giant cell development", "d": ["The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0097712", "l": "vesicle targeting, trans-Golgi to periciliary membrane compartment", "d": ["The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090094", "l": "metanephric cap mesenchymal cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010184", "l": "cytokinin transport", "d": ["The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900298", "l": "negative regulation of hexasaccharide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905093", "l": "cellular response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0051348", "l": "negative regulation of transferase activity", "d": ["Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046112", "l": "nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0010981", "l": "regulation of cell wall macromolecule metabolic process", "d": ["Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. 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Muscle tissue is a contractile tissue made up of actin and myosin fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902247", "l": "geranylgeranyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036394", "l": "amylase secretion", "d": ["The controlled release of amylase from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090110", "l": "COPII-coated vesicle cargo loading", "d": ["The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150176", "l": "positive regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010898", "l": "positive regulation of triglyceride catabolic process", "d": ["Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900314", "l": "positive regulation of maltohexaose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltohexaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990540", "l": "mitochondrial manganese ion transmembrane transport", "d": ["The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044149", "l": "positive regulation of formation of structure involved in a symbiotic process", "d": ["Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901147", "l": "mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002710", "l": "negative regulation of T cell mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140133", "l": "suppression by symbiont of host cytokine production", "d": ["Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902899", "l": "fatty acid methyl ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty acid methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0003129", "l": "heart induction", "d": ["The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.16494433675436", "identifiers": [{"i": "GO:0007127", "l": "meiosis I", "d": ["The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070475", "l": "rRNA base methylation", "d": ["The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042420", "l": "dopamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.233048187013779", "identifiers": [{"i": "GO:0010604", "l": "positive regulation of macromolecule metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0042634", "l": "regulation of hair cycle", "d": ["Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900992", "l": "(-)-secologanin metabolic process", "d": ["The chemical reactions and pathways involving (-)-secologanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034460", "l": "uropod assembly", "d": ["The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060771", "l": "phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032065", "l": "maintenance of protein location in cell cortex", "d": ["A process in which a protein or protein complex is maintained in a specific location in the cell cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015885", "l": "5-formyltetrahydrofolate transport", "d": ["The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903848", "l": "negative regulation of aorta morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071029", "l": "nuclear ncRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903586", "l": "positive regulation of histone deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075519", "l": "microtubule-dependent intracellular transport of viral material", "d": ["The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045312", "l": "nor-spermidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035024", "l": "negative regulation of Rho protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061357", "l": "positive regulation of Wnt protein secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036235", "l": "acyl deglucuronidation", "d": ["The removal of glucuronic acid from an acyl-glucuronide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:2000030", "l": "regulation of response to red or far red light", "d": ["Any process that modulates the frequency, rate or extent of response to red or far red light."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905199", "l": "manchette disassembly", "d": ["The disaggregation of a manchette into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072266", "l": "metanephric capsule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0061136", "l": "regulation of proteasomal protein catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042308", "l": "negative regulation of protein import into nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045646", "l": "regulation of erythrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903284", "l": "positive regulation of glutathione peroxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097705", "l": "vascular endothelial cell response to pulsatile fluid shear stress", "d": ["Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035233", "l": "germ cell repulsion", "d": ["The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905747", "l": "negative regulation of saliva secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070487", "l": "monocyte aggregation", "d": ["The adhesion of one monocyte to one or more other monocytes via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901753", "l": "leukotriene A4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene A4."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000904", "l": "regulation of starch metabolic process", "d": ["Any process that modulates the frequency, rate or extent of starch metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031293", "l": "membrane protein intracellular domain proteolysis", "d": ["The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.381710255175513", "identifiers": [{"i": "GO:0031399", "l": "regulation of protein modification process", "d": ["Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042753", "l": "positive regulation of circadian rhythm", "d": ["Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903074", "l": "TRAIL death-inducing signaling complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015009", "l": "corrin metabolic process", "d": ["The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903026", "l": "negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019464", "l": "glycine decarboxylation via glycine cleavage system", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019418", "l": "sulfide oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902972", "l": "premeiotic DNA replication DNA ligation", "d": ["Any DNA ligation involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010070", "l": "zygote asymmetric cell division", "d": ["The division of the zygote into two daughter cells that will adopt developmentally distinct potentials."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048216", "l": "negative regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160076", "l": "negative regulation of non-canonical inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 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"biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060916", "l": "mesenchymal cell proliferation involved in lung development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. 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A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046833", "l": "positive regulation of RNA export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903066", "l": "regulation of protein localization to cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048282", "l": "determinate inflorescence morphogenesis", "d": ["The process in which the anatomical structures of determinate inflorescences are generated and organized. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904345", "l": "negative regulation of gastric mucosal blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015834", "l": "peptidoglycan-associated peptide transport", "d": ["The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904848", "l": "negative regulation of cell chemotaxis to fibroblast growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0032505", "l": "reproduction of a single-celled organism", "d": ["The biological process in which new individuals are produced by one or two single-celled organisms. 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The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.017691718149159", "identifiers": [{"i": "GO:0006865", "l": "amino acid transport", "d": ["The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003415", "l": "chondrocyte hypertrophy", "d": ["The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060256", "l": "regulation of flocculation", "d": ["Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": 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in the formation of shamixanthone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030703", "l": "eggshell formation", "d": ["Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051096", "l": "positive regulation of helicase activity", "d": ["Any process that activates or increases the activity of a helicase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048076", "l": "regulation of compound eye pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055110", "l": "involution involved in gastrulation with mouth forming second", "d": ["The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0090317", "l": "negative regulation of intracellular protein transport", "d": ["Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046330", "l": "positive regulation of JNK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903893", "l": "positive regulation of ATF6-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of 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"d": ["The progression of an ectodermal placode over time from its initial formation until its mature state. 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The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070372", "l": "regulation of ERK1 and ERK2 cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000047", "l": "regulation of cell-cell adhesion mediated by cadherin", "d": ["Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090137", "l": "epithelial cell-cell adhesion involved in epithelium migration", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901493", "l": "response to decalin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098700", "l": "neurotransmitter loading into synaptic vesicle", "d": ["The active transport of neurotransmitters into a synaptic vesicle. 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Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072131", "l": "kidney mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. 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B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900095", "l": "regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0043628", "l": "regulatory ncRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051152", "l": "positive regulation of smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:2000696", "l": "regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0002705", "l": "positive regulation of leukocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006522", "l": "alanine metabolic process", "d": ["The chemical reactions and pathways involving alanine, 2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0043434", "l": "response to peptide hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106022", "l": "positive regulation of vesicle docking", "d": ["Any process that activates or increases the frequency, rate or extent of vesicle docking."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018178", "l": "peptidyl-threonine adenylylation", "d": ["The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002779", "l": "antibacterial peptide secretion", "d": ["The regulated release of an antibacterial peptide from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045971", "l": "positive regulation of juvenile hormone catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051465", "l": "negative regulation of corticotropin-releasing hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009845", "l": "seed germination", "d": ["The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043537", "l": "negative regulation of blood vessel endothelial cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.339867169364453", "identifiers": [{"i": "GO:0006366", "l": "transcription by RNA polymerase II", "d": ["The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006356", "l": "regulation of transcription by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903120", "l": "protein localization to actin filament bundle", "d": ["A process in which a protein is transported to, or maintained in, the location of an actin filament bundle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044510", "l": "envenomation resulting in positive regulation of signal transduction in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0046643", "l": "regulation of gamma-delta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001154", "l": "regulation of glycolytic fermentation to ethanol", "d": ["Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007506", "l": "gonadal mesoderm development", "d": ["The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002490", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.189287888426115", "identifiers": [{"i": "GO:0043933", "l": "protein-containing complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070817", "l": "P-TEFb-cap methyltransferase complex localization", "d": ["Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072390", "l": "phenol metabolic process", "d": ["The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000689", "l": "actomyosin contractile ring assembly actin filament organization", "d": ["An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000148", "l": "regulation of planar cell polarity pathway involved in ventricular septum morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0035150", "l": "regulation of tube size", "d": ["Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097750", "l": "endosome membrane tubulation", "d": ["A membrane tubulation process occurring in an endosome membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048252", "l": "lauric acid metabolic process", "d": ["The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0033151", "l": "V(D)J recombination", "d": ["The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032833", "l": "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060592", "l": "mammary gland formation", "d": ["The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031468", "l": "nuclear membrane reassembly", "d": ["The reformation of the nuclear membranes following their breakdown in the context of a normal process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990485", "l": "anaerobic lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006972", "l": "hyperosmotic response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901163", "l": "regulation of trophoblast cell migration", "d": ["Any process that modulates the frequency, rate or extent of trophoblast cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903379", "l": "regulation of mitotic chromosome condensation", "d": ["Any process that modulates the frequency, rate or extent of mitotic chromosome condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072635", "l": "interleukin-31 production", "d": ["The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0062022", "l": "mitotic cohesin ssDNA (lagging strand) loading", "d": ["The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106061", "l": "negative regulation of exit from meiosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072764", "l": "cellular response to reversine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905642", "l": "negative regulation of DNA methylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0036066", "l": "protein O-linked fucosylation", "d": ["The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0051783", "l": "regulation of nuclear division", "d": ["Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010788", "l": "COPI coating of Golgi vesicle, cis-Golgi to rough ER", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070662", "l": "mast cell proliferation", "d": ["The expansion of a mast cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900888", "l": "negative regulation of pentadecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060225", "l": "positive regulation of retinal rod cell fate commitment", "d": ["Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033685", "l": "negative regulation of luteinizing hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060217", "l": "hemangioblast cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901708", "l": "(+)-3'-hydroxylarreatricin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0090697", "l": "post-embryonic plant organ morphogenesis", "d": ["Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990974", "l": "actin-dependent nuclear migration", "d": ["The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016133", "l": "brassinosteroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110079", "l": "regulation of placenta blood vessel development", "d": ["Any process that modulates the frequency, rate or extent of placenta blood vessel development."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0070050", "l": "neuron cellular homeostasis", "d": ["The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0010463", "l": "mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0052039", "l": "perturbation by symbiont of host cytoskeleton", "d": ["The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035855", "l": "megakaryocyte development", "d": ["The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061301", "l": "cerebellum vasculature morphogenesis", "d": ["The process in which the vasculature of the cerebellum is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000038", "l": "very long-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0009164", "l": "nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043703", "l": "photoreceptor cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018378", "l": "cytochrome c-heme linkage via heme-L-cysteine", "d": ["The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034093", "l": "positive regulation of maintenance of sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0046125", "l": "pyrimidine deoxyribonucleoside metabolic process", "d": ["The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031385", "l": "regulation of termination of mating projection growth", "d": ["Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061381", "l": "cell migration in diencephalon", "d": ["The orderly movement of a cell that will reside in the diencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.08567671964029", "identifiers": [{"i": "GO:0048592", "l": "eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031134", "l": "sister chromatid biorientation", "d": ["The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902079", "l": "D-valine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044465", "l": "modulation of sensory perception of pain in another organism", "d": ["A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046199", "l": "cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110040", "l": "pharynx morphogenesis", "d": ["The process in which the anatomical structures of the pharynx are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901837", "l": "negative regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010312", "l": "detoxification of zinc ion", "d": ["Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900847", "l": "negative regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060942", "l": "neural crest-derived cardiac fibroblast cell differentiation", "d": ["The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000861", "l": "regulation of estrogen secretion", "d": ["Any process that modulates the frequency, rate or extent of estrogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043478", "l": "pigment accumulation in response to UV light", "d": ["The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042218", "l": "1-aminocyclopropane-1-carboxylate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904199", "l": "positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003286", "l": "atrial septum intermedium development", "d": ["The progression of the atrial septum intermedium over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901941", "l": "(+)-epi-alpha-bisabolol metabolic process", "d": ["The chemical reactions and pathways involving (+)-epi-alpha-bisabolol."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:2000889", "l": "cellodextrin metabolic process", "d": ["The chemical reactions and pathways involving a cellodextrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003032", "l": "detection of oxygen", "d": ["The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0015919", "l": "peroxisomal membrane transport", "d": ["The directed movement of substances to, from or across the peroxisomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.517713470395833", "identifiers": [{"i": "GO:0035825", "l": "homologous recombination", "d": ["A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046222", "l": "aflatoxin metabolic process", "d": ["The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002334", "l": "transitional two stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903126", "l": "negative regulation of centriole-centriole cohesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070277", "l": "iodide oxidation", "d": ["The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901060", "l": "p-hydroxyphenyl lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006218", "l": "uridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000353", "l": "positive regulation of endothelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901283", "l": "5,6,7,8-tetrahydromethanopterin metabolic process", "d": ["The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1902931", "l": "negative regulation of alcohol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010509", "l": "intracellular polyamine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000084", "l": "regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045836", "l": "positive regulation of meiotic nuclear division", "d": ["Any process that activates or increases the frequency, rate or extent of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006429", "l": "leucyl-tRNA aminoacylation", "d": ["The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021556", "l": "central nervous system formation", "d": ["The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904759", "l": "protein localization to equatorial microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010947", "l": "negative regulation of meiotic joint molecule formation", "d": ["Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0030832", "l": "regulation of actin filament length", "d": ["Any process that controls the length of actin filaments in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060903", "l": "positive regulation of meiosis I", "d": ["Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042892", "l": "chloramphenicol transmembrane transport", "d": ["The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062085", "l": "positive regulation of capsule polysaccharide biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0060456", "l": "positive regulation of digestive system process", "d": ["Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990451", "l": "cellular stress response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048294", "l": "negative regulation of isotype switching to IgE isotypes", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019250", "l": "aerobic cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018029", "l": "peptidyl-lysine palmitoylation", "d": ["The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042262", "l": "DNA protection", "d": ["Any process in which DNA is protected from damage by, for example, oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1902991", "l": "regulation of amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048906", "l": "anterior lateral line neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901287", "l": "iron-sulfur-molybdenum cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000275", "l": "regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900769", "l": "fonsecin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fonsecin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010516", "l": "negative regulation of cellular response to nitrogen starvation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903798", "l": "regulation of miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902818", "l": "ethyl acetate metabolic process", "d": ["The chemical reactions and pathways involving ethyl acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.975184980816103", "identifiers": [{"i": "GO:0071805", "l": "potassium ion transmembrane transport", "d": ["A process in which a potassium ion is transported from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901126", "l": "candicidin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of candicidin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010568", "l": "regulation of budding cell apical bud growth", "d": ["Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034343", "l": "type III interferon production", "d": ["The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051030", "l": "snRNA transport", "d": ["The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903494", "l": "response to dehydroepiandrosterone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902482", "l": "regulatory T cell apoptotic process", "d": ["Any apoptotic process in a regulatory T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090112", "l": "COPII vesicle uncoating", "d": ["The process in which COPII vesicle coat proteins are disassembled, and released."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045497", "l": "female analia development", "d": ["The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900848", "l": "positive regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006284", "l": "base-excision repair", "d": ["In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0045859", "l": "regulation of protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900627", "l": "negative regulation of arugosin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902787", "l": "cellular response to dodecane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000970", "l": "regulation of detection of glucose", "d": ["Any process that modulates the frequency, rate or extent of detection of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052041", "l": "suppression by symbiont of host programmed cell death", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036349", "l": "galactose-specific flocculation", "d": ["The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075505", "l": "entry of intact viral capsid into host nucleus through nuclear pore complex", "d": ["Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900305", "l": "positive regulation of laminaritriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of laminaritriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.885542599809028", "identifiers": [{"i": "GO:0006997", "l": "nucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048321", "l": "axial mesodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904352", "l": "positive regulation of protein catabolic process in the vacuole", "d": ["Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090109", "l": "regulation of cell-substrate junction assembly", "d": ["Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061153", "l": "trachea gland development", "d": ["The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2001017", "l": "regulation of retrograde axon cargo transport", "d": ["Any process that modulates the frequency, rate or extent of retrograde axon cargo transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905498", "l": "positive regulation of triplex DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of triplex DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035377", "l": "transepithelial water transport", "d": ["The directed movement of water (H2O) from one side of an epithelium to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046478", "l": "lactosylceramide metabolic process", "d": ["The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008587", "l": "imaginal disc-derived wing margin morphogenesis", "d": ["The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.831361051524119", "identifiers": [{"i": "GO:0015711", "l": "organic anion transport", "d": ["The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002525", "l": "acute inflammatory response to non-antigenic stimulus", "d": ["An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060620", "l": "regulation of cholesterol import", "d": ["Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036060", "l": "slit diaphragm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032202", "l": "telomere assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. 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The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000475", "l": "negative regulation of opioid receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0016116", "l": "carotenoid metabolic process", "d": ["The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042495", "l": "detection of triacyl bacterial lipopeptide", "d": ["The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990443", "l": "peptidyl-threonine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060782", "l": "regulation of mesenchymal cell proliferation involved in prostate gland development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0009237", "l": "siderophore metabolic process", "d": ["The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061925", "l": "negative regulation of formation of radial glial scaffolds", "d": ["Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009257", "l": "10-formyltetrahydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0072210", "l": "metanephric nephron development", "d": ["The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010408", "l": "fasciclin-like arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019090", "l": "mitochondrial rRNA export from mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902847", "l": "regulation of neuronal signal transduction", "d": ["Any process that modulates the frequency, rate or extent of neuronal signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021660", "l": "rhombomere 3 formation", "d": ["The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0002709", "l": "regulation of T cell mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of T cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001287", "l": "negative regulation of caveolin-mediated endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070950", "l": "regulation of neutrophil mediated killing of bacterium", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014732", "l": "skeletal muscle atrophy", "d": ["A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903672", "l": "positive regulation of sprouting angiogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010541", "l": "acropetal auxin transport", "d": ["The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048600", "l": "oocyte fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990592", "l": "protein K69-linked ufmylation", "d": ["A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010928", "l": "regulation of auxin mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021654", "l": "rhombomere boundary formation", "d": ["The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035993", "l": "deltoid tuberosity development", "d": ["The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046285", "l": "flavonoid phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903048", "l": "regulation of acetylcholine-gated cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019410", "l": "aerobic respiration, using carbon monoxide as electron donor", "d": ["The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905838", "l": "regulation of telomeric D-loop disassembly", "d": ["Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905141", "l": "negative regulation of apical ectodermal ridge formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075527", "l": "viral RNA editing", "d": ["The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.582168120318478", "identifiers": [{"i": "GO:0048519", "l": "negative regulation of biological process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072092", "l": "ureteric bud invasion", "d": ["The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010734", "l": "negative regulation of protein glutathionylation", "d": ["Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010984", "l": "regulation of lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014050", "l": "negative regulation of glutamate secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075272", "l": "regulation of zygosporangium development", "d": ["Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007282", "l": "cystoblast division", "d": ["Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036107", "l": "4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process", "d": ["The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N)."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.481265292451688", "identifiers": [{"i": "GO:0007292", "l": "female gamete generation", "d": ["Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052089", "l": "modulation by symbiont of host salicylic acid-mediated defense response", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071227", "l": "cellular response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070873", "l": "regulation of glycogen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000945", "l": "regulation of amylopectin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of amylopectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:1901334", "l": "lactone metabolic process", "d": ["The chemical reactions and pathways involving lactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075240", "l": "regulation of zoospore formation", "d": ["Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090264", "l": "regulation of immune complex clearance by monocytes and macrophages", "d": ["Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007323", "l": "peptide pheromone maturation", "d": ["The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072008", "l": "glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900927", "l": "negative regulation of L-threonine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009937", "l": "regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900268", "l": "regulation of reverse transcription", "d": ["Any process that modulates the frequency, rate or extent of reverse transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900289", "l": "negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0042490", "l": "mechanoreceptor differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901512", "l": "(-)-microperfuranone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-microperfuranone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021634", "l": "optic nerve formation", "d": ["The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035854", "l": "eosinophil fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900787", "l": "naphtho-gamma-pyrone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905607", "l": "negative regulation of presynapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086071", "l": "atrial cardiac muscle cell-AV node cell adhesion involved in cell communication", "d": ["The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042184", "l": "xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036234", "l": "deglucuronidation", "d": ["The removal of glucuronic acid from a conjugated substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904132", "l": "positive regulation of convergent extension involved in neural plate elongation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048829", "l": "root cap development", "d": ["The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000612", "l": "regulation of thyroid-stimulating hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002404", "l": "antigen sampling in mucosal-associated lymphoid tissue", "d": ["The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021832", "l": "cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions", "d": ["The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0099622", "l": "cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033395", "l": "beta-alanine biosynthetic process via 3-hydroxypropionate", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048387", "l": "negative regulation of retinoic acid receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904817", "l": "serous membrane development", "d": ["The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052150", "l": "modulation by symbiont of host apoptotic process", "d": ["Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0048199", "l": "vesicle targeting, to, from or within Golgi", "d": ["The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019526", "l": "pentitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902226", "l": "regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0050867", "l": "positive regulation of cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097350", "l": "neutrophil clearance", "d": ["The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090255", "l": "cell proliferation involved in imaginal disc-derived wing morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033271", "l": "myo-inositol phosphate transport", "d": ["The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001714", "l": "endodermal cell fate specification", "d": ["The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060947", "l": "cardiac vascular smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007594", "l": "puparial adhesion", "d": ["The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031273", "l": "negative regulation of pseudopodium assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003242", "l": "cardiac chamber ballooning", "d": ["The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001881", "l": "receptor recycling", "d": ["The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072631", "l": "interleukin-29 production", "d": ["The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046077", "l": "dUDP metabolic process", "d": ["The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903347", "l": "negative regulation of bicellular tight junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060608", "l": "cell-cell adhesion involved in neural tube closure", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032981", "l": "mitochondrial respiratory chain complex I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902380", "l": "positive regulation of endoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of endoribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120145", "l": "protein localization to basal ectoplasmic specialization", "d": ["A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061042", "l": "vascular wound healing", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018251", "l": "peptidyl-tyrosine dehydrogenation", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007118", "l": "budding cell apical bud growth", "d": ["Growth at the tip of a bud, in a cell that reproduces by budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.632870622771613", "identifiers": [{"i": "GO:0022412", "l": "cellular process involved in reproduction in multicellular organism", "d": ["A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045739", "l": "positive regulation of DNA repair", "d": ["Any process that activates or increases the frequency, rate or extent of DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904917", "l": "L-arginine transmembrane transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019595", "l": "non-phosphorylated glucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060628", "l": "regulation of ER to Golgi vesicle-mediated transport", "d": ["Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009932", "l": "cell tip growth", "d": ["Growth that occurs specifically at the tip of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016558", "l": "protein import into peroxisome matrix", "d": ["The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009601", "l": "detection of insect", "d": ["The series of events in which a stimulus from an insect is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900106", "l": "positive regulation of hyaluranon cable assembly", "d": ["Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080094", "l": "response to trehalose-6-phosphate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060279", "l": "positive regulation of ovulation", "d": ["Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033033", "l": "negative regulation of myeloid cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0018126", "l": "protein hydroxylation", "d": ["The addition of a hydroxy group to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034149", "l": "positive regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000261", "l": "negative regulation of blood coagulation, common pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010599", "l": "lsiRNA processing", "d": ["A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071655", "l": "regulation of granulocyte colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035683", "l": "memory T cell extravasation", "d": ["The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019463", "l": "glycine catabolic process to creatine", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060273", "l": "crying behavior", "d": ["The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905087", "l": "positive regulation of bioluminescence", "d": ["Any process that activates or increases the frequency, rate or extent of bioluminescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903858", "l": "protein localization to old growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within an old growing cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009709", "l": "terpenoid indole alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0030978", "l": "alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002919", "l": "positive regulation of peripheral B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033343", "l": "positive regulation of collagen binding", "d": ["Any process that activates or increases the frequency, rate or extent of collagen binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110081", "l": "negative regulation of placenta blood vessel development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0030656", "l": "regulation of vitamin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0021513", "l": "spinal cord dorsal/ventral patterning", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015920", "l": "lipopolysaccharide transport", "d": ["The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097103", "l": "endothelial stalk cell fate specification", "d": ["The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051964", "l": "negative regulation of synapse assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035172", "l": "hemocyte proliferation", "d": ["The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018163", "l": "protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine", "d": ["The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0030639", "l": "polyketide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000782", "l": "regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0009069", "l": "serine family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061960", "l": "regulation of heme oxygenase activity", "d": ["Any process that modulates the frequency, or rate of heme oxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901894", "l": "regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903359", "l": "lateral cortical node assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071973", "l": "bacterial-type flagellum-dependent cell motility", "d": ["Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014703", "l": "oscillatory muscle contraction", "d": ["A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006948", "l": "induction by virus of host cell-cell fusion", "d": ["The process of syncytia-forming cell-cell fusion, caused by a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014038", "l": "regulation of Schwann cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106097", "l": "cellular response to ceramide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042851", "l": "L-alanine metabolic process", "d": ["The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001191", "l": "regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.812551020734105", "identifiers": [{"i": "GO:0033036", "l": "macromolecule localization", "d": ["Any process in which a macromolecule is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035307", "l": "positive regulation of protein dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002896", "l": "negative regulation of central B cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045592", "l": "regulation of cumulus cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039022", "l": "pronephric duct development", "d": ["The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900287", "l": "positive regulation of cellotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019309", "l": "mannose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001680", "l": "tRNA 3'-terminal CCA addition", "d": ["Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006829", "l": "zinc ion transport", "d": ["The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061438", "l": "renal system vasculature morphogenesis", "d": ["The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051275", "l": "beta-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110019", "l": "IRES-dependent translational initiation of circular RNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048889", "l": "neuromast support cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000783", "l": "negative regulation of establishment of cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042948", "l": "salicin transport", "d": ["The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032727", "l": "positive regulation of interferon-alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0070977", "l": "bone maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901885", "l": "2-hydroxybenzoyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042952", "l": "beta-ketoadipate pathway", "d": ["A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1990395", "l": "meiotic spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902646", "l": "regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905946", "l": "negative regulation of response to calcium ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061888", "l": "regulation of astrocyte activation", "d": ["Any process that modulates the frequency, rate or extent of astrocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042203", "l": "toluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990960", "l": "basophil homeostasis", "d": ["The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009169", "l": "purine ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048452", "l": "petal structural organization", "d": ["The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009203", "l": "ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019683", "l": "glyceraldehyde-3-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904023", "l": "regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043977", "l": "histone H2A-K5 acetylation", "d": ["The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.988400485557229", "identifiers": [{"i": "GO:0030217", "l": "T cell differentiation", "d": ["The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903592", "l": "positive regulation of lysozyme activity", "d": ["Any process that activates or increases the frequency, rate or extent of lysozyme activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060670", "l": "branching involved in labyrinthine layer morphogenesis", "d": ["The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904441", "l": "regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070490", "l": "protein pupylation", "d": ["The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006226", "l": "dUMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036302", "l": "atrioventricular canal development", "d": ["The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046845", "l": "branched duct epithelial cell fate determination, open tracheal system", "d": ["Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051229", "l": "meiotic spindle disassembly", "d": ["The controlled breakdown of the spindle during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902772", "l": "positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway", "d": ["Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044849", "l": "estrous cycle", "d": ["A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.697407499888214", "identifiers": [{"i": "GO:0034250", "l": "positive regulation of amide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021806", "l": "initiation of movement involved in cerebral cortex radial glia guided migration", "d": ["The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098669", "l": "superinfection exclusion", "d": ["The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000016", "l": "negative regulation of determination of dorsal identity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0034088", "l": "maintenance of mitotic sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900810", "l": "helvolic acid metabolic process", "d": ["The chemical reactions and pathways involving helvolic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071846", "l": "actin filament debranching", "d": ["An actin filament severing process that results in the removal of actin filament branches specifically at the branch points."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0060561", "l": "apoptotic process involved in morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044350", "l": "micropinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072280", "l": "establishment of planar polarity involved in metanephric nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903714", "l": "isoleucine transmembrane transport", "d": ["The directed movement of isoleucine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060699", "l": "regulation of endoribonuclease activity", "d": ["Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046588", "l": "negative regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075202", "l": "regulation of penetration hypha formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042797", "l": "tRNA transcription by RNA polymerase III", "d": ["The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006649", "l": "phospholipid transfer to membrane", "d": ["The transfer of a phospholipid from its site of synthesis to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019347", "l": "GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019272", "l": "L-alanine biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035163", "l": "embryonic hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0002062", "l": "chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043709", "l": "cell adhesion involved in single-species biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033690", "l": "positive regulation of osteoblast proliferation", "d": ["Any process that activates or increases the rate or extent of osteoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.022889380119096", "identifiers": [{"i": "GO:0051050", "l": "positive regulation of transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044845", "l": "chain elongation of O-linked mannose residue", "d": ["Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072766", "l": "centromere clustering at the mitotic interphase nuclear envelope", "d": ["The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045979", "l": "positive regulation of nucleoside metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010379", "l": "phaseic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010745", "l": "negative regulation of macrophage derived foam cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032233", "l": "positive regulation of actin filament bundle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072689", "l": "MCM complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990831", "l": "cellular response to carcinoembryonic antigen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010673", "l": "positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019358", "l": "nicotinate nucleotide salvage", "d": ["The generation of nicotinate nucleotide without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006593", "l": "ornithine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075298", "l": "regulation of zygospore formation", "d": ["Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160028", "l": "negative regulation of pyroptosis", "d": ["Any process that decreases the frequency, rate or extent of pyroptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051367", "l": "peptidyl-serine decanoylation", "d": ["The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099178", "l": "regulation of retrograde trans-synaptic signaling by endocanabinoid", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071573", "l": "shelterin complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:1904659", "l": "glucose transmembrane transport", "d": ["The process in which glucose is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903781", "l": "positive regulation of cardiac conduction", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061374", "l": "mammillothalamic axonal tract development", "d": ["The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902770", "l": "negative regulation of choline O-acetyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072765", "l": "centromere localization", "d": ["A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120185", "l": "MBF transcription complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032632", "l": "interleukin-3 production", "d": ["The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060689", "l": "cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903022", "l": "positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands", "d": ["Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097622", "l": "cytoplasmic translational elongation through polyproline stretches", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900188", "l": "negative regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061221", "l": "mesonephric mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075055", "l": "positive regulation of penetration peg formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051489", "l": "regulation of filopodium assembly", "d": ["Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061259", "l": "mesonephric glomerular mesangial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0030198", "l": "extracellular matrix organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048286", "l": "lung alveolus development", "d": ["The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051595", "l": "response to methylglyoxal", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051517", "l": "negative regulation of bipolar cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015702", "l": "chlorate transport", "d": ["The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.198535815504115", "identifiers": [{"i": "GO:0071692", "l": "protein localization to extracellular region", "d": ["Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034756", "l": "regulation of iron ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019383", "l": "(+)-camphor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003251", "l": "positive regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010773", "l": "meiotic DNA recombinase assembly involved in meiotic gene conversion", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018865", "l": "acrylonitrile metabolic process", "d": ["The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009741", "l": "response to brassinosteroid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0045822", "l": "negative regulation of heart contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042684", "l": "cardioblast cell fate commitment", "d": ["The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901684", "l": "arsenate ion transmembrane transport", "d": ["The process in which arsenate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904687", "l": "positive regulation of mitotic spindle disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046448", "l": "tropane alkaloid metabolic process", "d": ["The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070655", "l": "mechanosensory epithelium regeneration", "d": ["The regrowth of lost or destroyed mechanosensory epithelia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070213", "l": "protein auto-ADP-ribosylation", "d": ["The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0098712", "l": "L-glutamate import across plasma membrane", "d": ["The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033025", "l": "regulation of mast cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of mast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072305", "l": "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902267", "l": "regulation of polyamine transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of polyamine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061964", "l": "negative regulation of entry into reproductive diapause", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901177", "l": "lycopene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lycopene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002192", "l": "IRES-dependent translational initiation of linear mRNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009950", "l": "dorsal/ventral axis specification", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051658", "l": "maintenance of nucleus location", "d": ["Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098924", "l": "retrograde trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1905144", "l": "response to acetylcholine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033630", "l": "positive regulation of cell adhesion mediated by integrin", "d": ["Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051599", "l": "response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035157", "l": "negative regulation of fusion cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0019395", "l": "fatty acid oxidation", "d": ["The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903678", "l": "negative regulation of cap-independent translational initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030578", "l": "PML body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035483", "l": "gastric emptying", "d": ["The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031017", "l": "exocrine pancreas development", "d": ["The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0019852", "l": "L-ascorbic acid metabolic process", "d": ["The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902632", "l": "positive regulation of membrane hyperpolarization", "d": ["Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0006213", "l": "pyrimidine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052034", "l": "effector-mediated suppression of host pattern-triggered immunity", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001813", "l": "regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003418", "l": "growth plate cartilage chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046360", "l": "2-oxobutyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006500", "l": "N-terminal protein palmitoylation", "d": ["The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032229", "l": "negative regulation of synaptic transmission, GABAergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900185", "l": "positive regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061010", "l": "gallbladder development", "d": ["The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006799", "l": "polyphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042618", "l": "poly-hydroxybutyrate metabolic process", "d": ["The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021862", "l": "early neuron differentiation in forebrain", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900738", "l": "positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006907", "l": "pinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0070167", "l": "regulation of biomineral tissue development", "d": ["Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010160", "l": "formation of animal organ boundary", "d": ["The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035740", "l": "CD8-positive, alpha-beta T cell proliferation", "d": ["The expansion of a CD8-positive, alpha-beta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060642", "l": "white fat cell differentiation involved in mammary gland fat development", "d": ["The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000338", "l": "protein deneddylation", "d": ["The removal of a ubiquitin-like protein of the NEDD8 type from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045454", "l": "cell redox homeostasis", "d": ["Any process that maintains the redox environment of a cell or compartment within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090261", "l": "positive regulation of inclusion body assembly", "d": ["Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046331", "l": "lateral inhibition", "d": ["Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099562", "l": "maintenance of postsynaptic density structure", "d": ["A process which maintains the organization and the arrangement of proteins in the presynaptic density."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003428", "l": "chondrocyte intercalation involved in growth plate cartilage morphogenesis", "d": ["The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060892", "l": "limb basal epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120211", "l": "proacrosomal vesicle fusion", "d": ["Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902140", "l": "response to inositol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046426", "l": "negative regulation of receptor signaling pathway via JAK-STAT", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010791", "l": "DNA double-strand break processing involved in repair via synthesis-dependent strand annealing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0002347", "l": "response to tumor cell", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035899", "l": "suppression of blood coagulation in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007494", "l": "midgut development", "d": ["The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990431", "l": "priRNA 3'-end processing", "d": ["The process of forming the mature 3' end of a priRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018265", "l": "GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075283", "l": "sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140236", "l": "translation at presynapse", "d": ["Translation that occurs at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000300", "l": "regulation of synaptic vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903584", "l": "regulation of histone deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003265", "l": "regulation of primary heart field cardioblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051972", "l": "regulation of telomerase activity", "d": ["Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0051017", "l": "actin filament bundle assembly", "d": ["The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045751", "l": "negative regulation of Toll signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051958", "l": "methotrexate transport", "d": ["The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0050680", "l": "negative regulation of epithelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070168", "l": "negative regulation of biomineral tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099074", "l": "mitochondrion to lysosome transport", "d": ["Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0005981", "l": "regulation of glycogen catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120046", "l": "regulation of protein localization to medial cortical node", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032744", "l": "positive regulation of interleukin-20 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0046390", "l": "ribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098819", "l": "depolarization of postsynaptic membrane", "d": ["A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097048", "l": "dendritic cell apoptotic process", "d": ["Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001298", "l": "N(omega),N(omega)-dimethyl-L-arginine metabolic process", "d": ["The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098953", "l": "receptor diffusion trapping", "d": ["The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009957", "l": "epidermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902483", "l": "cytotoxic T cell pyroptotic process", "d": ["Any pyroptotic process in a cytotoxic T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0002462", "l": "tolerance induction to nonself antigen", "d": ["Tolerance induction in response to nonself antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031456", "l": "glycine betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1900190", "l": "regulation of single-species biofilm formation", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000207", "l": "negative regulation of ribosomal small subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006276", "l": "plasmid maintenance", "d": ["The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072653", "l": "interferon-omega production", "d": ["The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990775", "l": "endothelin production", "d": ["The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048442", "l": "sepal development", "d": ["The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090171", "l": "chondrocyte morphogenesis", "d": ["The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055108", "l": "Golgi to transport vesicle transport", "d": ["The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034116", "l": "positive regulation of heterotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1904892", "l": "regulation of receptor signaling pathway via STAT", "d": ["Any process that modulates the frequency, rate or extent of receptor signaling via STAT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120315", "l": "positive regulation of oocyte karyosome formation", "d": ["Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901745", "l": "prephenate(2-) metabolic process", "d": ["The chemical reactions and pathways involving prephenate(2-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0042214", "l": "terpene metabolic process", "d": ["The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900309", "l": "regulation of maltoheptaose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034628", "l": "'de novo' NAD biosynthetic process from aspartate", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019340", "l": "dibenzofuran catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080003", "l": "thalianol metabolic process", "d": ["The chemical reactions and pathways involving the triterpene thalianol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019580", "l": "galactarate metabolic process", "d": ["The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071031", "l": "nuclear mRNA surveillance of mRNA 3'-end processing", "d": ["The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0032885", "l": "regulation of polysaccharide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061213", "l": "positive regulation of mesonephros development", "d": ["Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030540", "l": "female genitalia development", "d": ["The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034720", "l": "histone H3-K4 demethylation", "d": ["The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:0050777", "l": "negative regulation of immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001971", "l": "negative regulation of activation of membrane attack complex", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010440", "l": "stomatal lineage progression", "d": ["The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904350", "l": "regulation of protein catabolic process in the vacuole", "d": ["Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120188", "l": "regulation of bile acid secretion", "d": ["Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990267", "l": "response to transition metal nanoparticle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007014", "l": "actin ubiquitination", "d": ["The modification of actin by addition of ubiquitin groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015703", "l": "chromate transport", "d": ["The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019698", "l": "D-galacturonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.496985616080835", "identifiers": [{"i": "GO:0016070", "l": "RNA metabolic process", "d": ["The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060619", "l": "cell migration involved in mammary placode formation", "d": ["The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097707", "l": "ferroptosis", "d": ["A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0035966", "l": "response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903523", "l": "negative regulation of blood circulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045949", "l": "positive regulation of phosphorus utilization", "d": ["Any process that activates or increases the frequency, rate or extent of phosphorus utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.73602946617558", "identifiers": [{"i": "GO:0016571", "l": "histone methylation", "d": ["The modification of histones by addition of methyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002265", "l": "astrocyte activation involved in immune response", "d": ["A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060964", "l": "regulation of miRNA-mediated gene silencing", "d": ["A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0048440", "l": "carpel development", "d": ["The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014868", "l": "cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003173", "l": "ventriculo bulbo valve development", "d": ["The progression of the ventriculo bulbo valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003274", "l": "endocardial cushion fusion", "d": ["The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007117", "l": "budding cell bud growth", "d": ["The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902110", "l": "positive regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035817", "l": "renal sodium ion absorption involved in negative regulation of renal sodium excretion", "d": ["Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0048569", "l": "post-embryonic animal organ development", "d": ["Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060530", "l": "smooth muscle cell differentiation involved in prostate glandular acinus development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905176", "l": "positive regulation of vascular associated smooth muscle cell dedifferentiation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901760", "l": "beta-L-Ara4N-lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902156", "l": "positive regulation of response to G1 DNA damage checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000885", "l": "galactoglucomannan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035135", "l": "post-embryonic anal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009204", "l": "deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001245", "l": "regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905020", "l": "positive regulation of methionine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075216", "l": "positive regulation of spore encystment on host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036159", "l": "inner dynein arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140084", "l": "sexual macrocyst formation", "d": ["The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046304", "l": "2-nitropropane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0000288", "l": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160024", "l": "Leydig cell proliferation", "d": ["The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901355", "l": "response to rapamycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0030336", "l": "negative regulation of cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902979", "l": "mitotic DNA replication termination", "d": ["Any DNA replication termination involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099113", "l": "negative regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that decreases the concentration of calcium ions in the presynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090442", "l": "trehalose catabolism in response to heat stress", "d": ["The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071076", "l": "RNA 3' uridylation", "d": ["The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090059", "l": "protoxylem development", "d": ["The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048201", "l": "vesicle targeting, plasma membrane to endosome", "d": ["The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034769", "l": "basement membrane disassembly", "d": ["The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902261", "l": "positive regulation of delayed rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006293", "l": "nucleotide-excision repair, preincision complex stabilization", "d": ["The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0033334", "l": "fin morphogenesis", "d": ["The process in which the anatomical structures of a fin are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902031", "l": "regulation of NADP metabolic process", "d": ["Any process that modulates the frequency, rate or extent of NADP metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003246", "l": "embryonic cardiac muscle cell growth involved in heart morphogenesis", "d": ["The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140921", "l": "negative regulation of thermomorphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090388", "l": "phagosome-lysosome docking involved in apoptotic cell clearance", "d": ["The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051780", "l": "behavioral response to nutrient", "d": ["Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0032204", "l": "regulation of telomere maintenance", "d": ["Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033364", "l": "mast cell secretory granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031221", "l": "arabinan metabolic process", "d": ["The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903755", "l": "positive regulation of SUMO transferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of SUMO transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0003056", "l": "regulation of vascular associated smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vascular smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072068", "l": "late distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140480", "l": "mitotic spindle pole body insertion into the nuclear envelope", "d": ["A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0051056", "l": "regulation of small GTPase mediated signal transduction", "d": ["Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030491", "l": "heteroduplex formation", "d": ["The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036032", "l": "neural crest cell delamination", "d": ["The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0048087", "l": "positive regulation of developmental pigmentation", "d": ["Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901316", "l": "positive regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002746", "l": "antigen processing and presentation following pinocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099068", "l": "postsynapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046814", "l": "coreceptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036447", "l": "cellular response to sugar-phosphate stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904311", "l": "response to gold(3+)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904903", "l": "ESCRT III complex disassembly", "d": ["The disaggregation of an ESCRT III complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003139", "l": "secondary heart field specification", "d": ["The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018293", "l": "protein-FAD linkage", "d": ["The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034439", "l": "lipoprotein lipid oxidation", "d": ["The modification of a lipoprotein by oxidation of the lipid group."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030654", "l": "beta-lactam antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051143", "l": "propanediol metabolic process", "d": ["The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007113", "l": "endomitotic cell cycle", "d": ["A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900925", "l": "positive regulation of glycine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of glycine import."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033215", "l": "reductive iron assimilation", "d": ["A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010214", "l": "seed coat development", "d": ["The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071263", "l": "negative regulation of translational initiation in response to starvation", "d": ["Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097700", "l": "vascular endothelial cell response to laminar fluid shear stress", "d": ["Any response to laminar fluid shear stress in a vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019100", "l": "male germ-line sex determination", "d": ["The determination of sex and sexual phenotype in a male organism's germ line."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.095260031314808", "identifiers": [{"i": "GO:0003014", "l": "renal system process", "d": ["A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120161", "l": "regulation of cold-induced thermogenesis", "d": ["Any process that modulates the frequency, rate or extent of cold-induced thermogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0002696", "l": "positive regulation of leukocyte activation", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902371", "l": "negative regulation of tRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0001745", "l": "compound eye morphogenesis", "d": ["The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032110", "l": "regulation of protein histidine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of protein histidine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072086", "l": "specification of loop of Henle identity", "d": ["The process in which the loop of Henle of the kidney nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043438", "l": "acetoacetic acid metabolic process", "d": ["The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039682", "l": "rolling circle viral DNA replication", "d": ["A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0046173", "l": "polyol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046244", "l": "salicylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902132", "l": "(+)-lariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141081", "l": "symbiont-mediated suppression of host inflammasome-mediated signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or stops an inflammasome-mediated signal transduction pathway in the host organism by interfering with its normal execution. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033687", "l": "osteoblast proliferation", "d": ["The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003153", "l": "closure of embryonic heart tube", "d": ["Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042344", "l": "indole glucosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035645", "l": "enteric smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033311", "l": "chlorophyll a biosynthetic process via phytyl diphosphate", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002155", "l": "regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051895", "l": "negative regulation of focal adhesion assembly", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090437", "l": "socket cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003405", "l": "optic vesicle elongation", "d": ["The developmental growth that results in the lengthening of the optic vesicle in the posterior direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902803", "l": "regulation of synaptic vesicle transport", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.749288388108862", "identifiers": [{"i": "GO:0006412", "l": "translation", "d": ["The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900913", "l": "positive regulation of olefin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060657", "l": "regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling", "d": ["Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904157", "l": "DN4 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072039", "l": "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0050808", "l": "synapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048774", "l": "cyanophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035186", "l": "syncytial blastoderm mitotic cell cycle", "d": ["Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090672", "l": "telomerase RNA localization", "d": ["Any process in which telomerase RNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021869", "l": "forebrain ventricular zone progenitor cell division", "d": ["The mitotic division of a basal progenitor giving rise to two neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061817", "l": "endoplasmic reticulum-plasma membrane tethering", "d": ["The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019396", "l": "gallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0051712", "l": "positive regulation of killing of cells of another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070758", "l": "regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150103", "l": "reactive gliosis", "d": ["A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902738", "l": "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000910", "l": "negative regulation of sterol import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sterol import."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090737", "l": "telomere maintenance via telomere trimming", "d": ["A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0048675", "l": "axon extension", "d": ["Long distance growth of a single axon process involved in cellular development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043420", "l": "anthranilate metabolic process", "d": ["The chemical reactions and pathways involving anthranilate (2-aminobenzoate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903788", "l": "positive regulation of glutathione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048239", "l": "negative regulation of DNA recombination at telomere", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043410", "l": "positive regulation of MAPK cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903307", "l": "positive regulation of regulated secretory pathway", "d": ["Any process that activates or increases the frequency, rate or extent of regulated secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045346", "l": "regulation of MHC class II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072722", "l": "response to amitrole", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043321", "l": "regulation of natural killer cell degranulation", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904876", "l": "negative regulation of DNA ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046498", "l": "S-adenosylhomocysteine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0046634", "l": "regulation of alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902606", "l": "regulation of large conductance calcium-activated potassium channel activity", "d": ["Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0072594", "l": "establishment of protein localization to organelle", "d": ["The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060965", "l": "negative regulation of miRNA-mediated gene silencing", "d": ["A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032331", "l": "negative regulation of chondrocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905240", "l": "negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046107", "l": "uracil biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901961", "l": "isobutanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isobutanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0061620", "l": "glycolytic process through glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061148", "l": "extracellular matrix organization involved in endocardium development", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901930", "l": "alpha-copaene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-copaene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071668", "l": "plant-type cell wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0043487", "l": "regulation of RNA stability", "d": ["Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990294", "l": "peptidyl-threonine trans-autophosphorylation", "d": ["The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0048799", "l": "animal organ maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019690", "l": "pyrimidine deoxyribonucleoside interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099139", "l": "cheating during chimeric sorocarp development", "d": ["Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002035", "l": "brain renin-angiotensin system", "d": ["The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:2000191", "l": "regulation of fatty acid transport", "d": ["Any process that modulates the frequency, rate or extent of fatty acid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021638", "l": "trigeminal nerve formation", "d": ["The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000373", "l": "Group II intron splicing", "d": ["The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902330", "l": "synthesis of RNA primer involved in bacterial-type DNA replication", "d": ["Any synthesis of RNA primer that is involved in bacterial-type DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051091", "l": "positive regulation of DNA-binding transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.332759152575946", "identifiers": [{"i": "GO:0009888", "l": "tissue development", "d": ["The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055048", "l": "anastral spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010803", "l": "regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0043173", "l": "nucleotide salvage", "d": ["Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046258", "l": "anaerobic 2,4,6-trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072681", "l": "fibronectin-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097184", "l": "response to azide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043692", "l": "monoterpene metabolic process", "d": ["The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0050684", "l": "regulation of mRNA processing", "d": ["Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032335", "l": "regulation of activin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904701", "l": "Wnt-Frizzled-LRP5/6 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060480", "l": "lung goblet cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140742", "l": "lncRNA transcription", "d": ["The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0010453", "l": "regulation of cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046052", "l": "UTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904649", "l": "regulation of fat cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of fat cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902909", "l": "negative regulation of melanosome transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019045", "l": "latent virus replication", "d": ["Any process required for latent viral replication in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045224", "l": "positive regulation of CD4 production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032930", "l": "positive regulation of superoxide anion generation", "d": ["Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022033", "l": "telencephalon microglial cell migration", "d": ["The orderly movement of microglial cells through the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072061", "l": "inner medullary collecting duct development", "d": ["The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010795", "l": "regulation of ubiquinone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.096636849693901", "identifiers": [{"i": "GO:0070588", "l": "calcium ion transmembrane transport", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901622", "l": "positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "d": ["Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0048663", "l": "neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031586", "l": "negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072763", "l": "cellular response to hesperadin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032343", "l": "aldosterone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.704640979746422", "identifiers": [{"i": "GO:0015844", "l": "monoamine transport", "d": ["The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046462", "l": "monoacylglycerol metabolic process", "d": ["The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905682", "l": "positive regulation of innate immunity memory response", "d": ["Any process that activates or increases the frequency, rate or extent of innate immunity memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900012", "l": "positive regulation of corticotropin-releasing hormone receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110089", "l": "regulation of hippocampal neuron apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0003084", "l": "positive regulation of systemic arterial blood pressure", "d": ["The process that increases the force with which blood travels through the systemic arterial circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904216", "l": "positive regulation of protein import into chloroplast stroma", "d": ["Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010236", "l": "plastoquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007038", "l": "endocytosed protein transport to vacuole", "d": ["The directed movement of proteins imported into a cell by endocytosis to the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021606", "l": "accessory nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018144", "l": "RNA-protein covalent cross-linking", "d": ["The formation of a covalent cross-link between RNA and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000857", "l": "positive regulation of mineralocorticoid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051632", "l": "negative regulation of acetylcholine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0042756", "l": "drinking behavior", "d": ["The specific behavior of an organism relating to the intake of liquids, especially water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003225", "l": "left ventricular trabecular myocardium morphogenesis", "d": ["The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042976", "l": "activation of Janus kinase activity", "d": ["The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048789", "l": "cytoskeletal matrix organization at active zone", "d": ["The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0150065", "l": "regulation of deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of deacetylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033396", "l": "beta-alanine biosynthetic process via 3-ureidopropionate", "d": ["The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0019720", "l": "Mo-molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075069", "l": "adhesion of symbiont infection cushion to host", "d": ["The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001145", "l": "negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007392", "l": "initiation of dorsal closure", "d": ["Events that occur at the start of dorsal closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035573", "l": "N-terminal peptidyl-serine trimethylation", "d": ["The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030724", "l": "testicular fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903441", "l": "protein localization to ciliary membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140201", "l": "urea import across plasma membrane", "d": ["The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045901", "l": "positive regulation of translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902038", "l": "positive regulation of hematopoietic stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072351", "l": "tricarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904513", "l": "negative regulation of initiation of premeiotic DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000943", "l": "negative regulation of amylopectin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070961", "l": "positive regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000006", "l": "regulation of metanephric comma-shaped body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043480", "l": "pigment accumulation in tissues", "d": ["The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021590", "l": "cerebellum maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035823", "l": "short tract gene conversion", "d": ["A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0042088", "l": "T-helper 1 type immune response", "d": ["An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018937", "l": "nitroglycerin metabolic process", "d": ["The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009903", "l": "chloroplast avoidance movement", "d": ["The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072065", "l": "long descending thin limb bend development", "d": ["The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0032507", "l": "maintenance of protein location in cell", "d": ["Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071365", "l": "cellular response to auxin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902829", "l": "regulation of spinal cord association neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051067", "l": "dihydropteridine metabolic process", "d": ["The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052702", "l": "cellular modified histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903067", "l": "negative regulation of protein localization to cell tip", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045489", "l": "pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070901", "l": "mitochondrial tRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045705", "l": "negative regulation of salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0006970", "l": "response to osmotic stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070809", "l": "negative regulation of Hulle cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901066", "l": "syringal lignin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of syringal lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000435", "l": "negative regulation of protein neddylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0036006", "l": "cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045752", "l": "positive regulation of Toll signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.923685701360682", "identifiers": [{"i": "GO:0016192", "l": "vesicle-mediated transport", "d": ["A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061362", "l": "negative regulation of maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901022", "l": "4-hydroxyphenylacetate metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxyphenylacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070148", "l": "mitochondrial glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043377", "l": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002030", "l": "inhibitory G protein-coupled receptor phosphorylation", "d": ["The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050947", "l": "negative regulation of early stripe melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.588454143880355", "identifiers": [{"i": "GO:0072330", "l": "monocarboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045048", "l": "protein insertion into ER membrane", "d": ["The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072423", "l": "response to DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.93094722630925", "identifiers": [{"i": "GO:0042221", "l": "response to chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903217", "l": "negative regulation of protein processing involved in protein targeting to mitochondrion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0110112", "l": "regulation of lipid transporter activity", "d": ["Any process that modulates the frequency, rate, or extent of lipid transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0019520", "l": "aldonic acid metabolic process", "d": ["The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018184", "l": "protein polyamination", "d": ["The modification of a protein amino acid by polyamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060290", "l": "transdifferentiation", "d": ["The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140872", "l": "viridicatumtoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.480280698451963", "identifiers": [{"i": "GO:0008406", "l": "gonad development", "d": ["The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. 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An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010625", "l": "positive regulation of Schwann cell proliferation", "d": ["Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015862", "l": "uridine transport", "d": ["The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0042476", "l": "odontogenesis", "d": ["The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045070", "l": "positive regulation of viral genome replication", "d": ["Any process that activates or increases the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0031047", "l": "regulatory ncRNA-mediated gene silencing", "d": ["A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902237", "l": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.848013378054922", "identifiers": [{"i": "GO:0007283", "l": "spermatogenesis", "d": ["The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019469", "l": "octopine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001502", "l": "cartilage condensation", "d": ["The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019731", "l": "antibacterial humoral response", "d": ["An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000979", "l": "positive regulation of forebrain neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034389", "l": "lipid droplet organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006179", "l": "guanosine salvage", "d": ["Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901102", "l": "gramicidin S catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gramicidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070607", "l": "regulation of cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072499", "l": "photoreceptor cell axon guidance", "d": ["The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0061842", "l": "microtubule organizing center localization", "d": ["Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008582", "l": "regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070171", "l": "negative regulation of tooth mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048385", "l": "regulation of retinoic acid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042439", "l": "ethanolamine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048170", "l": "positive regulation of long-term neuronal synaptic plasticity", "d": ["A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044082", "l": "perturbation of host small GTPase mediated signal transduction", "d": ["A process in which a symbiont alters or subverts a small GTPase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0042633", "l": "hair cycle", "d": ["The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0071697", "l": "ectodermal placode morphogenesis", "d": ["The process in which the anatomical structures of an ectodermal placode are generated and organized. 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Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.25778018697109", "identifiers": [{"i": "GO:2000242", "l": "negative regulation of reproductive process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032676", "l": "regulation of interleukin-7 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-7 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000296", "l": "spermine transport", "d": ["The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010336", "l": "gibberellic acid homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019123", "l": "peptidyl-methionine racemization", "d": ["The racemization of peptidyl-methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051673", "l": "disruption of plasma membrane integrity in another organism", "d": ["The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060588", "l": "negative regulation of lipoprotein lipid oxidation", "d": ["Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905591", "l": "regulation of optical nerve axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of optical nerve axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106278", "l": "regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001224", "l": "positive regulation of neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051363", "l": "peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein", "d": ["The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901647", "l": "positive regulation of synoviocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021973", "l": "corticospinal neuron axon decussation", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900851", "l": "positive regulation of pseurotin A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002128", "l": "tRNA nucleoside ribose methylation", "d": ["The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007403", "l": "glial cell fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902134", "l": "(+)-secoisolariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019659", "l": "glucose catabolic process to lactate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905883", "l": "regulation of triglyceride transport", "d": ["Any process that modulates the frequency, rate or extent of triglyceride transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002002", "l": "regulation of angiotensin levels in blood", "d": ["The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021990", "l": "neural plate formation", "d": ["The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001800", "l": "negative regulation of type IIb hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072090", "l": "mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901323", "l": "response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901259", "l": "chloroplast rRNA processing", "d": ["Any rRNA processing that takes place in chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035398", "l": "helper T cell enhancement of T cell mediated immune response", "d": ["Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002660", "l": "positive regulation of peripheral tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048496", "l": "maintenance of animal organ identity", "d": ["The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060995", "l": "cell-cell signaling involved in kidney development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010800", "l": "positive regulation of peptidyl-threonine phosphorylation", "d": ["Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070366", "l": "regulation of hepatocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901920", "l": "peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901290", "l": "succinyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006933", "l": "negative regulation of cell adhesion involved in substrate-bound cell migration", "d": ["The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903092", "l": "pyridoxine transmembrane transport", "d": ["The process in which pyridoxine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048702", "l": "embryonic neurocranium morphogenesis", "d": ["The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. 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An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042251", "l": "maintenance of polarity of larval imaginal disc epithelium", "d": ["The maintenance of an established polarized larval imaginal disc epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000927", "l": "regulation of cellodextrin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellodextrin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003283", "l": "atrial septum development", "d": ["The progression of the atrial septum over time, from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006565", "l": "L-serine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000347", "l": "positive regulation of hepatocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.929933841797123", "identifiers": [{"i": "GO:0060004", "l": "reflex", "d": ["An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032634", "l": "interleukin-5 production", "d": ["The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032770", "l": "positive regulation of monooxygenase activity", "d": ["Any process that activates or increases the activity of a monooxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002291", "l": "T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021584", "l": "pons formation", "d": ["The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033053", "l": "D-glutamine metabolic process", "d": ["The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045633", "l": "positive regulation of mechanoreceptor differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901122", "l": "bacitracin A metabolic process", "d": ["The chemical reactions and pathways involving bacitracin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1905477", "l": "positive regulation of protein localization to membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003364", "l": "lamellipodium assembly involved in mesendodermal cell migration", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034609", "l": "spicule insertion", "d": ["Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048756", "l": "sieve cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900073", "l": "regulation of neuromuscular synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140242", "l": "translation at postsynapse", "d": ["Translation that occurs at the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001542", "l": "ovulation from ovarian follicle", "d": ["The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904753", "l": "negative regulation of vascular associated smooth muscle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904140", "l": "negative regulation of microglial cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045772", "l": "positive regulation of autophagosome size", "d": ["Any process that increases autophagosome size."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903381", "l": "regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003340", "l": "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002541", "l": "activation of plasma proteins involved in acute inflammatory response", "d": ["Any process activating plasma proteins by proteolysis as part of an acute inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018289", "l": "molybdenum incorporation into metallo-sulfur cluster", "d": ["The incorporation of molybdenum into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060075", "l": "regulation of resting membrane potential", "d": ["Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045753", "l": "negative regulation of acetate catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046925", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine", "d": ["The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060402", "l": "calcium ion transport into cytosol", "d": ["The directed movement of calcium ions (Ca2+) into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043280", "l": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044856", "l": "plasma membrane raft localization", "d": ["Any process in which plasma membrane rafts are transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097111", "l": "endoplasmic reticulum-Golgi intermediate compartment organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061156", "l": "pulmonary artery morphogenesis", "d": ["The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032899", "l": "regulation of neurotrophin production", "d": ["Any process that modulates the frequency, rate, or extent of production of a neurotrophin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901364", "l": "funalenone metabolic process", "d": ["The chemical reactions and pathways involving funalenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046647", "l": "negative regulation of gamma-delta T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0040040", "l": "thermosensory behavior", "d": ["Behavior that is dependent upon the sensation of temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904356", "l": "regulation of telomere maintenance via telomere lengthening", "d": ["Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000059", "l": "negative regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042940", "l": "D-amino acid transport", "d": ["The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015856", "l": "cytosine transport", "d": ["The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900924", "l": "negative regulation of glycine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901757", "l": "butirosin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of butirosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060304", "l": "regulation of phosphatidylinositol dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901172", "l": "phytoene metabolic process", "d": ["The chemical reactions and pathways involving phytoene."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007484", "l": "imaginal disc-derived genitalia development", "d": ["The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061720", "l": "6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900692", "l": "regulation of (+)-kotanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015824", "l": "proline transport", "d": ["The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051688", "l": "maintenance of plastid location", "d": ["Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903844", "l": "regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046382", "l": "GDP-D-rhamnose metabolic process", "d": ["The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106212", "l": "centromere detachment from spindle pole body involved in meiotic chromosome organization", "d": ["The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072019", "l": "proximal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905556", "l": "ciliary vesicle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2001305", "l": "xanthone-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a xanthone-containing compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019617", "l": "protocatechuate catabolic process, meta-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0070787", "l": "conidiophore development", "d": ["The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1905962", "l": "glutamatergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905295", "l": "regulation of neural crest cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of neural crest cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901169", "l": "3-chlorocatechol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-chlorocatechol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090394", "l": "negative regulation of excitatory postsynaptic potential", "d": ["Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904470", "l": "regulation of endothelin production", "d": ["Any process that modulates the frequency, rate or extent of endothelin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010411", "l": "xyloglucan metabolic process", "d": ["The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901322", "l": "response to chloramphenicol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097484", "l": "dendrite extension", "d": ["Long distance growth of a single dendrite involved in cellular development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046645", "l": "positive regulation of gamma-delta T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035343", "l": "negative regulation of inosine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000354", "l": "cis assembly of pre-catalytic spliceosome", "d": ["Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901120", "l": "tobramycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tobramycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061002", "l": "negative regulation of dendritic spine morphogenesis", "d": ["Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. 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This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903676", "l": "positive regulation of cap-dependent translational initiation", "d": ["Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034642", "l": "mitochondrion migration along actin filament", "d": ["The directed movement of a mitochondrion along a microfilament, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0009651", "l": "response to salt stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035830", "l": "palmatine metabolic process", "d": ["The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0007162", "l": "negative regulation of cell adhesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061085", "l": "regulation of histone H3-K27 methylation", "d": ["Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. 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The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071663", "l": "positive regulation of granzyme B production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of granzyme B."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901858", "l": "regulation of mitochondrial DNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0030049", "l": "muscle filament sliding", "d": ["The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021666", "l": "rhombomere 5 formation", "d": ["The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015757", "l": "galactose transmembrane transport", "d": ["The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990386", "l": "mitotic cleavage furrow ingression", "d": ["Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007343", "l": "egg activation", "d": ["The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901185", "l": "negative regulation of ERBB signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903719", "l": "regulation of I-kappaB phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.926926926900272", "identifiers": [{"i": "GO:0007268", "l": "chemical synaptic transmission", "d": ["The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006929", "l": "substrate-dependent cell migration", "d": ["The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061939", "l": "c-di-GMP signaling", "d": ["Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901784", "l": "p-cresol metabolic process", "d": ["The chemical reactions and pathways involving p-cresol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072314", "l": "glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043306", "l": "positive regulation of mast cell degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of mast cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006298", "l": "mismatch repair", "d": ["A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002859", "l": "negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0001541", "l": "ovarian follicle development", "d": ["The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0008595", "l": "anterior/posterior axis specification, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072315", "l": "metanephric glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042065", "l": "glial cell growth", "d": ["Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042704", "l": "uterine wall breakdown", "d": ["The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0031023", "l": "microtubule organizing center organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000373", "l": "positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902190", "l": "2-methylbutanoyl-CoA(4-) catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "42.807218658408694", "identifiers": [{"i": "GO:0065008", "l": "regulation of biological quality", "d": ["Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0010594", "l": "regulation of endothelial cell migration", "d": ["Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070094", "l": "positive regulation of glucagon secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001316", "l": "kojic acid metabolic process", "d": ["The chemical reactions and pathways involving kojic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0050667", "l": "homocysteine metabolic process", "d": ["The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905446", "l": "regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.593796506745541", "identifiers": [{"i": "GO:0042127", "l": "regulation of cell population proliferation", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099564", "l": "modification of synaptic structure, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission via modification of the structure of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902127", "l": "(-)-lariciresinol metabolic process", "d": ["The chemical reactions and pathways involving (-)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0000963", "l": "mitochondrial RNA processing", "d": ["The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000501", "l": "regulation of natural killer cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0016117", "l": "carotenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "31.944301927609001", "identifiers": [{"i": "GO:0009653", "l": "anatomical structure morphogenesis", "d": ["The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009665", "l": "plastid inheritance", "d": ["The partitioning of plastids between daughter cells at cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045468", "l": "regulation of R8 cell spacing in compound eye", "d": ["Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900275", "l": "negative regulation of phospholipase C activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030903", "l": "notochord development", "d": ["The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045651", "l": "positive regulation of macrophage differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021729", "l": "superior reticular formation development", "d": ["The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034268", "l": "discadenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060772", "l": "leaf phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000764", "l": "positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.796949823561661", "identifiers": [{"i": "GO:0098542", "l": "defense response to other organism", "d": ["Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0006402", "l": "mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090356", "l": "negative regulation of auxin metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002279", "l": "mast cell activation involved in immune response", "d": ["The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006786", "l": "heme C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035700", "l": "astrocyte chemotaxis", "d": ["The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903810", "l": "L-histidine import across plasma membrane", "d": ["The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140274", "l": "repair of kinetochore microtubule attachment defect", "d": ["The cell cycle process where kinetochore microtubule attachment defects are corrected."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072000", "l": "extracellular polysaccharide catabolic process involved in ascospore release from ascus", "d": ["The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0043583", "l": "ear development", "d": ["The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018242", "l": "protein O-linked glycosylation via serine", "d": ["The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042842", "l": "D-xylose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044619", "l": "positive regulation of relaxation of uterine smooth muscle in another organism", "d": ["The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034436", "l": "glycoprotein transport", "d": ["The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900325", "l": "negative regulation of maltotriulose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000448", "l": "positive regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901585", "l": "regulation of acid-sensing ion channel activity", "d": ["Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903713", "l": "asparagine transmembrane transport", "d": ["The directed movement of asparagine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009372", "l": "quorum sensing", "d": ["The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902442", "l": "regulation of ripoptosome assembly involved in necroptotic process", "d": ["Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0048881", "l": "mechanosensory lateral line system development", "d": ["The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048907", "l": "anterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061113", "l": "pancreas morphogenesis", "d": ["Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0035306", "l": "positive regulation of dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0000917", "l": "division septum assembly", "d": ["The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031639", "l": "plasminogen activation", "d": ["The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043427", "l": "carbon fixation by 3-hydroxypropionate cycle", "d": ["An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051135", "l": "positive regulation of NK T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008612", "l": "peptidyl-lysine modification to peptidyl-hypusine", "d": ["The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097716", "l": "copper ion transport across blood-brain barrier", "d": ["The directed movement of copper (Cu) ions passing through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900270", "l": "positive regulation of reverse transcription", "d": ["Any process that activates or increases the frequency, rate or extent of reverse transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0046460", "l": "neutral lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048454", "l": "sepal structural organization", "d": ["The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0120178", "l": "steroid hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901631", "l": "positive regulation of presynaptic membrane organization", "d": ["Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061591", "l": "calcium activated galactosylceramide scrambling", "d": ["The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032823", "l": "regulation of natural killer cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018867", "l": "alpha-pinene metabolic process", "d": ["The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000794", "l": "regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043644", "l": "tetracycline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051917", "l": "regulation of fibrinolysis", "d": ["Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0008156", "l": "negative regulation of DNA replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900060", "l": "negative regulation of ceramide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:2001257", "l": "regulation of cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019404", "l": "galactitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990625", "l": "negative regulation of cytoplasmic translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905223", "l": "epicardium morphogenesis", "d": ["The developmental process by which an epicardium is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046985", "l": "positive regulation of hemoglobin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018962", "l": "3-phenylpropionate metabolic process", "d": ["The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0006403", "l": "RNA localization", "d": ["A process in which RNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075185", "l": "positive regulation of infection cushion formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001895", "l": "retina homeostasis", "d": ["A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901729", "l": "monensin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monensin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051167", "l": "xylulose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018013", "l": "N-terminal peptidyl-glycine methylation", "d": ["The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060220", "l": "camera-type eye photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003241", "l": "growth involved in heart morphogenesis", "d": ["Developmental growth that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015887", "l": "pantothenate transmembrane transport", "d": ["The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070307", "l": "lens fiber cell development", "d": ["The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019125", "l": "peptidyl-phenylalanine racemization", "d": ["The racemization of peptidyl-phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901953", "l": "positive regulation of anterograde dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904094", "l": "positive regulation of autophagic cell death", "d": ["Any process that activates or increases the frequency, rate or extent of autophagic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903090", "l": "pyridoxal transmembrane transport", "d": ["The process in which pyridoxal is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080029", "l": "cellular response to boron-containing substance levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036334", "l": "epidermal stem cell homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070832", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline", "d": ["The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071290", "l": "cellular response to platinum ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097088", "l": "interleukin-17F production", "d": ["The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070212", "l": "protein poly-ADP-ribosylation", "d": ["The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010034", "l": "response to acetate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050787", "l": "detoxification of mercury ion", "d": ["Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0])."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034298", "l": "arthrospore formation", "d": ["The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033336", "l": "caudal fin development", "d": ["The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904935", "l": "positive regulation of cell proliferation in midbrain", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035917", "l": "negative regulation of calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0043053", "l": "dauer entry", "d": ["Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904889", "l": "regulation of excitatory synapse assembly", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007354", "l": "zygotic determination of anterior/posterior axis, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021900", "l": "ventricular zone cell fate commitment", "d": ["The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905166", "l": "negative regulation of lysosomal protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.592359821609847", "identifiers": [{"i": "GO:1902476", "l": "chloride transmembrane transport", "d": ["The process in which chloride is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072146", "l": "DCT cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000997", "l": "regulation of cellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.969478998631025", "identifiers": [{"i": "GO:0051252", "l": "regulation of RNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072257", "l": "metanephric nephron tubule epithelial cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140641", "l": "mitotic spindle formation (spindle phase two)", "d": ["The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070306", "l": "lens fiber cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007438", "l": "oenocyte development", "d": ["The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002277", "l": "myeloid dendritic cell activation involved in immune response", "d": ["The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0055064", "l": "chloride ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070666", "l": "regulation of mast cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072121", "l": "head kidney maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0008347", "l": "glial cell migration", "d": ["The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1902337", "l": "regulation of apoptotic process involved in morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036275", "l": "response to 5-fluorouracil", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007084", "l": "mitotic nuclear membrane reassembly", "d": ["The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901732", "l": "quercetin metabolic process", "d": ["The chemical reactions and pathways involving quercetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006214", "l": "thymidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062177", "l": "radial spoke assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043643", "l": "tetracycline metabolic process", "d": ["The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015745", "l": "tartrate transmembrane transport", "d": ["The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032677", "l": "regulation of interleukin-8 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-8 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903127", "l": "positive regulation of centriole-centriole cohesion", "d": ["Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905832", "l": "positive regulation of spindle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of spindle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0050768", "l": "negative regulation of neurogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903911", "l": "positive regulation of receptor clustering", "d": ["Any process that activates or increases the frequency, rate or extent of receptor clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000348", "l": "regulation of CD40 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002926", "l": "tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "d": ["The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021684", "l": "cerebellar granular layer formation", "d": ["The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010101", "l": "post-embryonic root morphogenesis", "d": ["The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007465", "l": "R7 cell fate commitment", "d": ["The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060017", "l": "parathyroid gland development", "d": ["The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0006029", "l": "proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0040003", "l": "chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990414", "l": "replication-born double-strand break repair via sister chromatid exchange", "d": ["The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090643", "l": "inflorescence phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097475", "l": "motor neuron migration", "d": ["The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900311", "l": "positive regulation of maltoheptaose metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036104", "l": "Kdo2-lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.684144155919761", "identifiers": [{"i": "GO:0006518", "l": "peptide metabolic process", "d": ["The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904335", "l": "regulation of ductus arteriosus closure", "d": ["Any process that modulates the frequency, rate or extent of ductus arteriosus closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0008212", "l": "mineralocorticoid metabolic process", "d": ["The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046947", "l": "hydroxylysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021687", "l": "cerebellar molecular layer morphogenesis", "d": ["The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106024", "l": "negative regulation of pupariation", "d": ["Any process that stops, prevents or reduces the rate of onset of pupariation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060400", "l": "negative regulation of growth hormone receptor signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098693", "l": "regulation of synaptic vesicle cycle", "d": ["Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046205", "l": "nor-spermidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072729", "l": "cellular response to Gentian violet", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002858", "l": "regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901826", "l": "zeaxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of zeaxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:1902903", "l": "regulation of supramolecular fiber organization", "d": ["Any process that modulates the frequency, rate or extent of supramolecular fiber organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061589", "l": "calcium activated phosphatidylserine scrambling", "d": ["The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.969909400061496", "identifiers": [{"i": "GO:0009451", "l": "RNA modification", "d": ["The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904704", "l": "positive regulation of protein localization to adherens junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032463", "l": "negative regulation of protein homooligomerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044833", "l": "modulation by virus of host protein transport", "d": ["Any viral process that modulates the frequency, rate or extent of protein transport in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043608", "l": "formamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:2000833", "l": "positive regulation of steroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of steroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018119", "l": "peptidyl-cysteine S-nitrosylation", "d": ["The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072027", "l": "connecting tubule development", "d": ["The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044721", "l": "protein import into peroxisome matrix, substrate release", "d": ["The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000316", "l": "regulation of T-helper 17 type immune response", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 type immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046753", "l": "non-lytic viral release", "d": ["The exit of a viral particle from a host cell that does not involve cell lysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0018345", "l": "protein palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045226", "l": "extracellular polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046646", "l": "regulation of gamma-delta T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001197", "l": "basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any basement membrane assembly that is involved in embryonic body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032205", "l": "negative regulation of telomere maintenance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0016202", "l": "regulation of striated muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of striated muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071047", "l": "polyadenylation-dependent mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090163", "l": "establishment of epithelial cell planar polarity", "d": ["The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030177", "l": "positive regulation of Wnt signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003227", "l": "right ventricular trabecular myocardium morphogenesis", "d": ["The process in which the anatomical structures of the right ventricular myocardium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000661", "l": "positive regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of 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"flower structural organization", "d": ["The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030389", "l": "fructosamine metabolic process", "d": ["The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060448", "l": "dichotomous subdivision of terminal units involved in lung branching", "d": ["The process in which a lung bud bifurcates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000165", "l": "regulation of planar cell polarity pathway involved in pericardium morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009173", "l": "pyrimidine ribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034612", "l": "response to tumor necrosis factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071307", "l": "cellular response to vitamin K", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061554", "l": "ganglion formation", "d": ["The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043454", "l": "alkyne catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051902", "l": "negative regulation of mitochondrial depolarization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.697407499888214", "identifiers": [{"i": "GO:0098661", "l": "inorganic anion transmembrane transport", "d": ["The process in which an inorganic anion is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018185", "l": "poly-N-methyl-propylamination", "d": ["The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007486", "l": "imaginal disc-derived female genitalia development", "d": ["The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900056", "l": "negative regulation of leaf senescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010481", "l": "epidermal cell division", "d": ["Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019453", "l": "L-cysteine catabolic process via cystine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903923", "l": "positive regulation of protein processing in phagocytic vesicle", "d": ["Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034096", "l": "positive regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071269", "l": "L-homocysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034125", "l": "negative regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060162", "l": "negative regulation of phospholipase C-activating dopamine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0071063", "l": "sensory perception of wind", "d": ["The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014885", "l": "detection of injury involved in regulation of muscle adaptation", "d": ["The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901462", "l": "positive regulation of response to formic acid", "d": ["Any process that activates or increases the frequency, rate or extent of response to formic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904286", "l": "negative regulation of protein-pyridoxal-5-phosphate linkage", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002873", "l": "positive regulation of natural killer cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009778", "l": "cyclic photosynthetic phosphorylation", "d": ["A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0009235", "l": "cobalamin metabolic process", "d": ["The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072113", "l": "head kidney development", "d": ["The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0072530", "l": "purine-containing compound transmembrane transport", "d": ["The process in which a purine-containing compound is transported across a membrane. 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The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045631", "l": "regulation of mechanoreceptor differentiation", "d": ["Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000162", "l": "tryptophan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010841", "l": "positive regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035767", "l": "endothelial cell chemotaxis", "d": ["The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061469", "l": "regulation of type B pancreatic cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006449", "l": "regulation of translational termination", "d": ["Any process that modulates the frequency, rate or extent of translational termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902841", "l": "regulation of netrin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048198", "l": "Golgi vesicle bud deformation and release", "d": ["The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001032", "l": "regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010731", "l": "protein glutathionylation", "d": ["The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051884", "l": "regulation of timing of anagen", "d": ["Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000867", "l": "regulation of estrone secretion", "d": ["Any process that modulates the frequency, rate or extent of estrone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018903", "l": "1,3-dichloropropene metabolic process", "d": ["The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099548", "l": "trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905940", "l": "negative regulation of gonad development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901249", "l": "regulation of lung goblet cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lung goblet cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019346", "l": "transsulfuration", "d": ["The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006587", "l": "serotonin biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035706", "l": "T-helper 1 cell chemotaxis", "d": ["The directed movement of a T-helper 1 cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001016", "l": "positive regulation of skeletal muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042478", "l": "regulation of eye photoreceptor cell development", "d": ["Any process that modulates the frequency, rate or extent of eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990186", "l": "regulation of lymphatic vessel size", "d": ["Any process that modulates the size of lymphatic vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048923", "l": "posterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070235", "l": "regulation of activation-induced cell death of T cells", "d": ["Any process that modulates the occurrence or rate of activation-induced cell death of T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050933", "l": "early stripe melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043416", "l": "regulation of skeletal muscle tissue regeneration", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000354", "l": "regulation of ovarian follicle development", "d": ["Any process that modulates the frequency, rate or extent of ovarian follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061110", "l": "dense core granule biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0018023", "l": "peptidyl-lysine trimethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070889", "l": "platelet alpha granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009915", "l": "phloem sucrose loading", "d": ["The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0099188", "l": "postsynaptic cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902951", "l": "negative regulation of dendritic spine maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0034661", "l": "ncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036345", "l": "platelet maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010573", "l": "vascular endothelial growth factor production", "d": ["The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019360", "l": "nicotinamide nucleotide biosynthetic process from niacinamide", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0061383", "l": "trabecula morphogenesis", "d": ["The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006722", "l": "triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071585", "l": "detoxification of cadmium ion", "d": ["Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006111", "l": "regulation of gluconeogenesis", "d": ["Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141073", "l": "disruption by symbiont of host opsonization", "d": ["Any process in which a symbiont interferes with, inhibits or stops opsonization by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0090316", "l": "positive regulation of intracellular protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060806", "l": "negative regulation of cell differentiation involved in embryonic placenta development", "d": ["Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099140", "l": "presynaptic actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0060896", "l": "neural plate pattern specification", "d": ["The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0043939", "l": "negative regulation of sporulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061247", "l": "mesonephric glomerular mesangium development", "d": ["The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0007443", "l": "Malpighian tubule morphogenesis", "d": ["The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000388", "l": "spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)", "d": ["Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0038099", "l": "nodal receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048055", "l": "R2/R5 development", "d": ["The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018956", "l": "phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016561", "l": "protein import into peroxisome matrix, translocation", "d": ["The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071872", "l": "cellular response to epinephrine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051799", "l": "negative regulation of hair follicle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.200921040138688", "identifiers": [{"i": "GO:0007606", "l": "sensory perception of chemical stimulus", "d": ["The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018416", "l": "nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide", "d": ["The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031999", "l": "negative regulation of fatty acid beta-oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021539", "l": "subthalamus development", "d": ["The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090361", "l": "regulation of platelet-derived growth factor production", "d": ["Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036288", "l": "response to ximelagatran", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000195", "l": "negative regulation of female gonad development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007374", "l": "posterior midgut invagination", "d": ["Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000094", "l": "negative regulation of mesonephric nephron tubule epithelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048761", "l": "collenchyma cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0042359", "l": "vitamin D metabolic process", "d": ["The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0006575", "l": "cellular modified amino acid metabolic process", "d": ["The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019651", "l": "citrate catabolic process to diacetyl", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1902441", "l": "protein localization to meiotic spindle pole body", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001544", "l": "initiation of primordial ovarian follicle growth", "d": ["Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032753", "l": "positive regulation of interleukin-4 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-4 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900334", "l": "negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032784", "l": "regulation of DNA-templated transcription elongation", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010219", "l": "regulation of vernalization response", "d": ["Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000173", "l": "negative regulation of branching morphogenesis of a nerve", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070670", "l": "response to interleukin-4", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905578", "l": "regulation of ERBB3 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900283", "l": "negative regulation of cellobiose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010753", "l": "positive regulation of cGMP-mediated signaling", "d": ["Any process that increases the rate, frequency or extent of cGMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901791", "l": "3-(2,3-dihydroxyphenyl)propanoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002074", "l": "extraocular skeletal muscle development", "d": ["The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0048678", "l": "response to axon injury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903770", "l": "negative regulation of beta-galactosidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903210", "l": "podocyte apoptotic process", "d": ["Any apoptotic process in a glomerular visceral epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900307", "l": "negative regulation of maltoheptaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032946", "l": "positive regulation of mononuclear cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006546", "l": "glycine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900026", "l": "positive regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019553", "l": "glutamate catabolic process via L-citramalate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0016093", "l": "polyprenol metabolic process", "d": ["The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071279", "l": "cellular response to cobalt ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048802", "l": "notum morphogenesis", "d": ["The process in which the anatomical structures of the dorsal part of the body are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006491", "l": "N-glycan processing", "d": ["The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019629", "l": "propionate catabolic process, 2-methylcitrate cycle", "d": ["The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001112", "l": "DNA-templated transcription open complex formation", "d": ["Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001238", "l": "positive regulation of extrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0043266", "l": "regulation of potassium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060445", "l": "branching involved in salivary gland morphogenesis", "d": ["The process in which the branching structure of the salivary gland is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140241", "l": "translation at synapse", "d": ["Translation that occurs at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031541", "l": "negative regulation of anthocyanin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042672", "l": "retinal cone cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097091", "l": "synaptic vesicle clustering", "d": ["The process that results in grouping synaptic vesicles in presynaptic structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905086", "l": "negative regulation of bioluminescence", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903833", "l": "positive regulation of cellular response to amino acid starvation", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905904", "l": "positive regulation of mesoderm formation", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060278", "l": "regulation of ovulation", "d": ["Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071237", "l": "cellular response to bacteriocin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904476", "l": "negative regulation of small GTPase binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051155", "l": "positive regulation of striated muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0007039", "l": "protein catabolic process in the vacuole", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043319", "l": "positive regulation of cytotoxic T cell degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140614", "l": "1,8-dihydroxynaphthalene-melanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043316", "l": "cytotoxic T cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0052547", "l": "regulation of peptidase activity", "d": ["Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060209", "l": "estrus", "d": ["The estrous cycle phase in which a female is sexually receptive."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075256", "l": "regulation of teliospore formation", "d": ["Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032418", "l": "lysosome localization", "d": ["Any process in which a lysosome is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902788", "l": "response to isooctane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900862", "l": "negative regulation of cordyol C biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090188", "l": "negative regulation of pancreatic juice secretion", "d": ["Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903740", "l": "positive regulation of phosphatidate phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140464", "l": "subnuclear spatial organization of silent mating-type cassette heterochromatin", "d": ["The localization of silent mating-type cassette heterochromatin at a specific location in the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0016048", "l": "detection of temperature stimulus", "d": ["The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904566", "l": "cellular response to 1-oleoyl-sn-glycerol 3-phosphate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903806", "l": "L-isoleucine import across plasma membrane", "d": ["The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900854", "l": "positive regulation of terrequinone A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034131", "l": "regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048323", "l": "axial mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000978", "l": "negative regulation of forebrain neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0050854", "l": "regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070266", "l": "necroptotic process", "d": ["A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061360", "l": "optic chiasma development", "d": ["The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008616", "l": "queuosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0014856", "l": "skeletal muscle cell proliferation", "d": ["The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046473", "l": "phosphatidic acid metabolic process", "d": ["The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015767", "l": "lactose transport", "d": ["The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032381", "l": "negative regulation of intracellular sterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000743", "l": "nuclear migration involved in conjugation with cellular fusion", "d": ["The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034379", "l": "very-low-density lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030539", "l": "male genitalia development", "d": ["The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001765", "l": "membrane raft assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1903475", "l": "mitotic actomyosin contractile ring assembly", "d": ["Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0072224", "l": "metanephric glomerulus development", "d": ["The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900461", "l": "positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072579", "l": "glycine receptor clustering", "d": ["The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015744", "l": "succinate transport", "d": ["The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051601", "l": "exocyst localization", "d": ["Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903942", "l": "positive regulation of respiratory gaseous exchange", "d": ["Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042775", "l": "mitochondrial ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901788", "l": "benzoyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000733", "l": "regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140281", "l": "positive regulation of mitotic division septum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0097120", "l": "receptor localization to synapse", "d": ["Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072058", "l": "outer stripe development", "d": ["The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0009820", "l": "alkaloid metabolic process", "d": ["The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0035672", "l": "oligopeptide transmembrane transport", "d": ["The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000266", "l": "regulation of blood coagulation, intrinsic pathway", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030476", "l": "ascospore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060016", "l": "granulosa cell development", "d": ["The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0017008", "l": "protein-phycobiliviolin linkage", "d": ["The linkage of the chromophore phycobiliviolin to phycoerythrocyanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0007519", "l": "skeletal muscle tissue development", "d": ["The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061558", "l": "cranial ganglion maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002903", "l": "negative regulation of B cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140915", "l": "zinc ion import into zymogen granule", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042244", "l": "spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061999", "l": "regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0150172", "l": "regulation of phosphatidylcholine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010343", "l": "singlet oxygen-mediated programmed cell death", "d": ["Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000439", "l": "positive regulation of monocyte extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of monocyte extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090301", "l": "negative regulation of neural crest formation", "d": ["Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003011", "l": "involuntary skeletal muscle contraction", "d": ["A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018919", "l": "gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061128", "l": "positive regulation of chemotaxis to cAMP by DIF-2", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904976", "l": "cellular response to bleomycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006962", "l": "male-specific antibacterial humoral response", "d": ["An immune response against bacteria, specific to males and mediated through a body fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070550", "l": "rDNA chromatin condensation", "d": ["The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060636", "l": "negative regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.949061832187297", "identifiers": [{"i": "GO:0007517", "l": "muscle organ development", "d": ["The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097019", "l": "neurotransmitter receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010818", "l": "T cell chemotaxis", "d": ["The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061254", "l": "mesonephric glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009087", "l": "methionine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0009411", "l": "response to UV", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.306098259633643", "identifiers": [{"i": "GO:0080135", "l": "regulation of cellular response to stress", "d": ["Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071579", "l": "regulation of zinc ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021854", "l": "hypothalamus development", "d": ["The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902616", "l": "acyl carnitine transmembrane transport", "d": ["The process in which acyl carnitine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901932", "l": "bicyclogermacrene metabolic process", "d": ["The chemical reactions and pathways involving bicyclogermacrene."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0044381", "l": "glucose import in response to insulin stimulus", "d": ["The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021949", "l": "brainstem precerebellar neuron precursor migration", "d": ["The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.422285095499703", "identifiers": [{"i": "GO:0051247", "l": "positive regulation of protein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051798", "l": "positive regulation of hair follicle development", "d": ["Any process that activates or increases the frequency, rate or extent of hair follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021964", "l": "rubrospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0050891", "l": "multicellular organismal-level water homeostasis", "d": ["A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035648", "l": "circadian mating behavior", "d": ["The fluctuation in mating behavior that occurs over an approximately 24 hour cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010728", "l": "regulation of hydrogen peroxide biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905291", "l": "positive regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009616", "l": "RNAi-mediated antiviral immune response", "d": ["A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006748", "l": "lipoamide metabolic process", "d": ["The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043602", "l": "nitrate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0080182", "l": "histone H3-K4 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0007006", "l": "mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033320", "l": "UDP-D-xylose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018262", "l": "isopeptide cross-linking", "d": ["The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046491", "l": "L-methylmalonyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051413", "l": "response to cortisone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021756", "l": "striatum development", "d": ["The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048061", "l": "positive gravitaxis", "d": ["The directed movement of a motile cell or organism towards the source of gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090129", "l": "positive regulation of synapse maturation", "d": ["Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0098868", "l": "bone growth", "d": ["The increase in size or mass of a bone that contributes to the shaping of that bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014824", "l": "artery smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046188", "l": "methane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006564", "l": "L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001995", "l": "norepinephrine-epinephrine catabolic process in blood stream", "d": ["The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048800", "l": "antennal morphogenesis", "d": ["The process in which the anatomical structures of the antenna are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007477", "l": "notum development", "d": ["The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035040", "l": "sperm nuclear envelope removal", "d": ["Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009198", "l": "pyrimidine deoxyribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000449", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050992", "l": "dimethylallyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048448", "l": "stamen morphogenesis", "d": ["The process in which the anatomical structures of the stamen are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0141086", "l": "negative regulation of inflammasome-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044638", "l": "envenomation resulting in positive regulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120272", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150071", "l": "negative regulation of arginase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.618744678332945", "identifiers": [{"i": "GO:0060326", "l": "cell chemotaxis", "d": ["The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043484", "l": "regulation of RNA splicing", "d": ["Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018102", "l": "peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine", "d": ["The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006884", "l": "cell volume homeostasis", "d": ["Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904313", "l": "response to methamphetamine hydrochloride", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002106", "l": "endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033383", "l": "geranyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002500", "l": "proteolysis within lysosome associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902126", "l": "(+)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-pinoresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015943", "l": "formate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070208", "l": "protein heterotrimerization", "d": ["The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902888", "l": "protein localization to astral microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within an astral microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000616", "l": "negative regulation of histone H3-K9 acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099191", "l": "trans-synaptic signaling by BDNF", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007321", "l": "sperm displacement", "d": ["The physical displacement of sperm stored from previous mating encounters."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006065", "l": "UDP-glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050674", "l": "urothelial cell proliferation", "d": ["The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000745", "l": "nuclear migration involved in conjugation with mutual genetic exchange", "d": ["The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0006096", "l": "glycolytic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045706", "l": "positive regulation of salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035359", "l": "negative regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900100", "l": "positive regulation of plasma cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plasma cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014001", "l": "sclerenchyma cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034244", "l": "negative regulation of transcription elongation by RNA polymerase II", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1901722", "l": "regulation of cell proliferation involved in kidney development", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032487", "l": "regulation of Rap protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rap protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046336", "l": "ethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009710", "l": "tropane alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003169", "l": "coronary vein morphogenesis", "d": ["The process in which the anatomical structures of veins of the heart are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901938", "l": "(-)-exo-alpha-bergamotene metabolic process", "d": ["The chemical reactions and pathways involving (-)-exo-alpha-bergamotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0050658", "l": "RNA transport", "d": ["The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060378", "l": "regulation of brood size", "d": ["Any process that modulates brood size. 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Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045989", "l": "positive regulation of striated muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035678", "l": "neuromast hair cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060372", "l": "regulation of atrial cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000337", "l": "positive regulation of endothelial microparticle formation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045008", "l": "depyrimidination", "d": ["The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.441195081532641", "identifiers": [{"i": "GO:1903532", "l": "positive regulation of secretion by cell", "d": ["Any process that activates or increases the frequency, rate or extent of secretion by cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035938", "l": "estradiol secretion", "d": ["The regulated release of estradiol into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900632", "l": "tridecane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tridecane."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0014009", "l": "glial cell proliferation", "d": ["The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090707", "l": "establishment of plant organ orientation", "d": ["The process that determines the orientation of a plant organ or tissue with reference to an axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009861", "l": "jasmonic acid and ethylene-dependent systemic resistance", "d": ["The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.906789722440635", "identifiers": [{"i": "GO:0034660", "l": "ncRNA metabolic process", "d": ["The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2001185", "l": "regulation of CD8-positive, alpha-beta T cell activation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070392", "l": "detection of lipoteichoic acid", "d": ["The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0032392", "l": "DNA geometric change", "d": ["The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000424", "l": "micromitophagy", "d": ["Degradation of a mitochondrion by lysosomal microautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060915", "l": "mesenchymal cell differentiation involved in lung development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901608", "l": "regulation of vesicle transport along microtubule", "d": ["Any process that modulates the frequency, rate or extent of vesicle transport along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044468", "l": "envenomation resulting in modulation of blood coagulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042914", "l": "colicin transport", "d": ["The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039507", "l": "suppression by virus of host molecular function", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045578", "l": "negative regulation of B cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:2001243", "l": "negative regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099611", "l": "regulation of action potential firing threshold", "d": ["Any process that regulates the potential at which an axon potential is triggered."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050988", "l": "N-terminal peptidyl-methionine carboxylation", "d": ["The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018411", "l": "protein glucuronidation", "d": ["The modification of a protein by amino acid glucuronidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006152", "l": "purine nucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032207", "l": "regulation of telomere maintenance via recombination", "d": ["Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002720", "l": "positive regulation of cytokine production involved in immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0060433", "l": "bronchus development", "d": ["The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035442", "l": "dipeptide transmembrane transport", "d": ["The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:1902480", "l": "protein localization to mitotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a mitotic spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045681", "l": "positive regulation of R8 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of R8 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0048534", "l": "hematopoietic or lymphoid organ development", "d": ["The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046313", "l": "phosphoarginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900483", "l": "regulation of protein targeting to vacuolar membrane", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036152", "l": "phosphatidylethanolamine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090455", "l": "ornithine transmembrane import into vacuole", "d": ["The directed movement of ornithine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010187", "l": "negative regulation of seed germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120329", "l": "protein localization to centriolar satellite", "d": ["A process in which a protein is transported to, or maintained in, a location within a centriolar satellite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070981", "l": "L-asparagine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904387", "l": "cellular response to L-phenylalanine derivative", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140782", "l": "novofumigatonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990355", "l": "L-methionine salvage from methionine sulphoxide", "d": ["The generation of L-methionine from methionine sulphoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0030432", "l": "peristalsis", "d": ["A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0005982", "l": "starch metabolic process", "d": ["The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060515", "l": "prostate field specification", "d": ["The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018218", "l": "peptidyl-cysteine phosphorylation", "d": ["The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0051168", "l": "nuclear export", "d": ["The directed movement of substances out of the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:1902224", "l": "ketone body metabolic process", "d": ["The chemical reactions and pathways involving ketone body."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.020961935443736", "identifiers": [{"i": "GO:0048608", "l": "reproductive structure development", "d": ["The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075289", "l": "aplanospore formation", "d": ["The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.640334783545086", "identifiers": [{"i": "GO:0043085", "l": "positive regulation of catalytic activity", "d": ["Any process that activates or increases the activity of an enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0001773", "l": "myeloid dendritic cell activation", "d": ["The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903750", "l": "regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903783", "l": "negative regulation of sodium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019597", "l": "(R)-mandelate catabolic process to benzoate", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090152", "l": "establishment of protein localization to mitochondrial membrane involved in mitochondrial fission", "d": ["The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900939", "l": "negative regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021820", "l": "extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration", "d": ["The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:0061540", "l": "octopamine secretion, neurotransmission", "d": ["The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141064", "l": "zygotic genome activation", "d": ["A process that contributes to the onset of de novo transcription from the zygotic genome as part of the maternal-to-zygote transition in gene expression. The zygote overcomes the silencing that has been established. The cause of this silencing could be due to several factors: chromatin modifications leading to repression, or lack of adequate transcription machinery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110014", "l": "negative regulation of aggregation involved in sorocarp development", "d": ["Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070798", "l": "positive regulation of cleistothecium development", "d": ["Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042464", "l": "dosage compensation by hypoactivation of X chromosome", "d": ["Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002851", "l": "positive regulation of peripheral T cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904959", "l": "regulation of cytochrome-c oxidase activity", "d": ["Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032211", "l": "negative regulation of telomere maintenance via telomerase", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086049", "l": "membrane repolarization during AV node cell action potential", "d": ["The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905669", "l": "TORC1 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097296", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002608", "l": "negative regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.614083926907639", "identifiers": [{"i": "GO:0023057", "l": "negative regulation of signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032078", "l": "negative regulation of endodeoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097510", "l": "base-excision repair, AP site formation via deaminated base removal", "d": ["A base-excision repair, AP site formation process occurring via excision of a deaminated base."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0141005", "l": "retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism involving heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075284", "l": "asexual sporulation resulting in formation of a multicellular or syncytial spore", "d": ["The formation of a multicellular or syncytial spore via septations derived from mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071338", "l": "positive regulation of hair follicle cell proliferation", "d": ["Any process that activates or increases the rate or extent of hair follicle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070957", "l": "negative regulation of neutrophil mediated killing of gram-negative bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905033", "l": "positive regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009222", "l": "pyrimidine ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0009110", "l": "vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001101", "l": "maltopentaose transport", "d": ["The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030238", "l": "male sex determination", "d": ["The specification of male sex of an individual organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003244", "l": "radial growth involved in right ventricle morphogenesis", "d": ["The morphogenic growth in which the right ventricle grows along a radial axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.271958778998595", "identifiers": [{"i": "GO:0034249", "l": "negative regulation of amide metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033622", "l": "integrin activation", "d": ["The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901253", "l": "negative regulation of intracellular transport of viral material", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090325", "l": "regulation of locomotion involved in locomotory behavior", "d": ["Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061187", "l": "regulation of rDNA heterochromatin formation", "d": ["Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0060966", "l": "regulation of gene silencing by regulatory ncRNA", "d": ["Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0006278", "l": "RNA-templated DNA biosynthetic process", "d": ["A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1900430", "l": "positive regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904679", "l": "myo-inositol import across plasma membrane", "d": ["The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000389", "l": "mRNA 3'-splice site recognition", "d": ["Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046192", "l": "anaerobic phenol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900065", "l": "regulation of ethanol catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ethanol catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051103", "l": "DNA ligation involved in DNA repair", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0034766", "l": "negative regulation of monoatomic ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044029", "l": "positive regulation of gene expression via CpG island demethylation", "d": ["An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001173", "l": "regulation of histone H2B conserved C-terminal lysine ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045694", "l": "regulation of embryo sac egg cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038041", "l": "cross-receptor inhibition within G protein-coupled receptor heterodimer", "d": ["Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0035806", "l": "perturbation of blood coagulation in another organism", "d": ["The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098967", "l": "exocytic insertion of neurotransmitter receptor to postsynaptic membrane", "d": ["The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905163", "l": "negative regulation of phagosome maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002407", "l": "dendritic cell chemotaxis", "d": ["The movement of a dendritic cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905290", "l": "negative regulation of CAMKK-AMPK signaling cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042426", "l": "choline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904253", "l": "positive regulation of bile acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of bile acid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904376", "l": "negative regulation of protein localization to cell periphery", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030392", "l": "fructosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060374", "l": "mast cell differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070460", "l": "thyroid-stimulating hormone secretion", "d": ["The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905703", "l": "negative regulation of inhibitory synapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904518", "l": "protein localization to cytoplasmic microtubule plus-end", "d": ["A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045638", "l": "negative regulation of myeloid cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001263", "l": "regulation of C-C chemokine binding", "d": ["Any process that modulates the frequency, rate or extent of C-C chemokine binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030961", "l": "peptidyl-arginine hydroxylation", "d": ["The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901823", "l": "delta-carotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of delta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106230", "l": "protein depropionylation", "d": ["The removal of a propionyl group from a residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099141", "l": "cellular response to protozoan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035541", "l": "negative regulation of SNARE complex disassembly", "d": ["Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046419", "l": "octopine metabolic process", "d": ["The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904839", "l": "negative regulation of male germ-line stem cell asymmetric division", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051366", "l": "protein decanoylation", "d": ["The modification of a protein amino acid by formation of an ester or amide with decanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901388", "l": "regulation of transforming growth factor beta activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905568", "l": "regulation of ferrichrome biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000168", "l": "negative regulation of planar cell polarity pathway involved in neural tube closure", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061066", "l": "positive regulation of dauer larval development", "d": ["Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035190", "l": "syncytial nuclear migration", "d": ["The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901821", "l": "alpha-zeacarotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900580", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903174", "l": "fatty alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fatty alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061880", "l": "regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051479", "l": "mannosylglycerate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051519", "l": "activation of bipolar cell growth", "d": ["Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905748", "l": "hard palate morphogenesis", "d": ["The developmental process by which a hard palate is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034373", "l": "intermediate-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039669", "l": "viral entry into host cell via pilus retraction and membrane fusion", "d": ["The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072011", "l": "glomerular endothelium development", "d": ["The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002357", "l": "defense response to tumor cell", "d": ["Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000446", "l": "regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032980", "l": "keratinocyte activation", "d": ["A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035065", "l": "regulation of histone acetylation", "d": ["Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905544", "l": "L-methionine import across plasma membrane", "d": ["The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033327", "l": "Leydig cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904494", "l": "regulation of substance P secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051097", "l": "negative regulation of helicase activity", "d": ["Any process that stops or reduces the activity of a helicase."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090330", "l": "regulation of platelet aggregation", "d": ["Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.367368887635308", "identifiers": [{"i": "GO:1904062", "l": "regulation of monoatomic cation transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of cation transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901099", "l": "negative regulation of signal transduction in absence of ligand", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034625", "l": "fatty acid elongation, monounsaturated fatty acid", "d": ["Elongation of a fatty acid chain into which one C-C double bond has been introduced."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006477", "l": "protein sulfation", "d": ["The addition of a sulfate group as an ester to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021898", "l": "commitment of multipotent stem cells to neuronal lineage in forebrain", "d": ["The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044482", "l": "envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048488", "l": "synaptic vesicle endocytosis", "d": ["A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009650", "l": "UV protection", "d": ["Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042619", "l": "poly-hydroxybutyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043281", "l": "regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010636", "l": "positive regulation of mitochondrial fusion", "d": ["Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070759", "l": "negative regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062161", "l": "regulation of pyocyanine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019551", "l": "glutamate catabolic process to 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904193", "l": "negative regulation of cholangiocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905510", "l": "negative regulation of myosin II filament assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071460", "l": "cellular response to cell-matrix adhesion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0051307", "l": "meiotic chromosome separation", "d": ["The process in which chromosomes are physically detached from each other during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061945", "l": "regulation of protein K48-linked ubiquitination", "d": ["Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0009403", "l": "toxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046594", "l": "maintenance of pole plasm mRNA location", "d": ["The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0018117", "l": "protein adenylylation", "d": ["The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002435", "l": "immune complex clearance by erythrocytes", "d": ["The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002762", "l": "negative regulation of myeloid leukocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046159", "l": "ocellus pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000939", "l": "regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019749", "l": "cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte", "d": ["The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.404467932747075", "identifiers": [{"i": "GO:0019439", "l": "aromatic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019284", "l": "L-methionine salvage from S-adenosylmethionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048757", "l": "pigment granule maturation", "d": ["Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090708", "l": "specification of plant organ axis polarity", "d": ["The process in which the polarity of a plant organ axis is specified."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034164", "l": "negative regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904660", "l": "regulation of sensory perception of bitter taste", "d": ["Any process that modulates the frequency, rate or extent of sensory perception of bitter taste."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019097", "l": "pole plasm mitochondrial srRNA localization", "d": ["Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090248", "l": "cell migration involved in somitogenic axis elongation", "d": ["Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051645", "l": "Golgi localization", "d": ["Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045956", "l": "positive regulation of calcium ion-dependent exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901221", "l": "positive regulation of cardiac chamber morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0001655", "l": "urogenital system development", "d": ["The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902456", "l": "regulation of stomatal opening", "d": ["Any process that modulates the frequency, rate or extent of stomatal opening."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021566", "l": "hypoglossal nerve development", "d": ["The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905358", "l": "positive regulation of snRNA pseudouridine synthesis", "d": ["Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0072741", "l": "protein localization to cell division site", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003419", "l": "growth plate cartilage chondrocyte proliferation", "d": ["The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0030252", "l": "growth hormone secretion", "d": ["The regulated release of growth hormone from secretory granules into the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010102", "l": "lateral root morphogenesis", "d": ["The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903268", "l": "positive regulation of ornithine catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ornithine catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098676", "l": "modulation of host virulence by virus", "d": ["A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904819", "l": "parietal peritoneum development", "d": ["The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009199", "l": "ribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900667", "l": "regulation of endocrocin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032337", "l": "positive regulation of activin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045688", "l": "regulation of antipodal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of antipodal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901443", "l": "negative regulation of response to furfural", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0008206", "l": "bile acid metabolic process", "d": ["The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018321", "l": "protein glucuronylation", "d": ["The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019700", "l": "organic phosphonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098517", "l": "detection of low humidity", "d": ["The series of events in which low humidity is detected and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000702", "l": "regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904392", "l": "cellular response to ciliary neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904028", "l": "positive regulation of collagen fibril organization", "d": ["Any process that activates or increases the frequency, rate or extent of collagen fibril organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031556", "l": "transcriptional attenuation by ribosome", "d": ["A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098880", "l": "maintenance of postsynaptic specialization structure", "d": ["A process which maintains the organization and the arrangement of proteins in the presynaptic specialization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010663", "l": "positive regulation of striated muscle cell apoptotic process", "d": ["Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009089", "l": "lysine biosynthetic process via diaminopimelate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006539", "l": "glutamate catabolic process via 2-oxoglutarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903093", "l": "regulation of protein K48-linked deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015864", "l": "pyrimidine nucleoside transport", "d": ["The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071654", "l": "positive regulation of chemokine (C-C motif) ligand 1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010220", "l": "positive regulation of vernalization response", "d": ["Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0045123", "l": "cellular extravasation", "d": ["The migration of a leukocyte from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039534", "l": "negative regulation of MDA-5 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051039", "l": "positive regulation of transcription involved in meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009704", "l": "de-etiolation", "d": ["The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0090175", "l": "regulation of establishment of planar polarity", "d": ["Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0042749", "l": "regulation of circadian sleep/wake cycle", "d": ["Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090178", "l": "regulation of establishment of planar polarity involved in neural tube closure", "d": ["Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0007062", "l": "sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021627", "l": "olfactory nerve morphogenesis", "d": ["The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036067", "l": "light-dependent chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015786", "l": "UDP-glucose transmembrane transport", "d": ["The process in which UDP-glucose is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900284", "l": "positive regulation of cellobiose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007274", "l": "neuromuscular synaptic transmission", "d": ["The process of synaptic transmission from a neuron to a muscle, across a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0090085", "l": "regulation of protein deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein deubiquitination. 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This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0072338", "l": "lactam metabolic process", "d": ["The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033132", "l": "negative regulation of glucokinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900617", "l": "emericellamide A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of emericellamide A."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0045875", "l": "negative regulation of sister chromatid cohesion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048842", "l": "positive regulation of axon extension involved in axon guidance", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900767", "l": "fonsecin metabolic process", "d": ["The chemical reactions and pathways involving fonsecin."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0000209", "l": "protein polyubiquitination", "d": ["Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901096", "l": "regulation of autophagosome maturation", "d": ["Any process that modulates the frequency, rate or extent of autophagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046057", "l": "dADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140406", "l": "L-alanine export across the plasma membrane", "d": ["The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990792", "l": "cellular response to glial cell derived neurotrophic factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044484", "l": "envenomation resulting in fibrinolysis in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036100", "l": "leukotriene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1900371", "l": "regulation of purine nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0120193", "l": "tight junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. 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An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901586", "l": "negative regulation of acid-sensing ion channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904505", "l": "regulation of telomere maintenance in response to DNA damage", "d": ["Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046802", "l": "exit of virus from host cell nucleus by nuclear egress", "d": ["The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. 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[{"i": "GO:0002897", "l": "positive regulation of central B cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032631", "l": "interleukin-27 production", "d": ["The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010362", "l": "negative regulation of anion channel activity by blue light", "d": ["Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0097421", "l": "liver regeneration", "d": ["The regrowth of lost or destroyed liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019306", "l": "GDP-D-rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046497", "l": "nicotinate nucleotide metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0034284", "l": "response to monosaccharide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044537", "l": "regulation of circulating fibrinogen levels", "d": ["Any process that modulates the quantity of fibrinogen circulating in the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903014", "l": "cellular response to differentiation-inducing factor 1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031549", "l": "negative regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019390", "l": "glucuronoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905302", "l": "negative regulation of macropinocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043642", "l": "novobiocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031552", "l": "negative regulation of brain-derived 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and presentation following receptor mediated endocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021811", "l": "growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration", "d": ["Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901709", "l": "(+)-larreatricin metabolic process", "d": ["The chemical reactions and pathways involving (+)-larreatricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010889", "l": "regulation of sequestering of triglyceride", "d": ["Any process that modulates the rate, frequency or extent 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Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0021826", "l": "substrate-independent telencephalic tangential migration", "d": ["The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.065389299478184", "identifiers": [{"i": "GO:0006885", "l": "regulation of pH", "d": ["Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070234", "l": "positive regulation of T cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903336", "l": "negative regulation of vacuolar transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0001818", "l": "negative regulation of cytokine production", "d": ["Any process that stops, prevents, or reduces the rate of production of a cytokine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010842", "l": "retina layer formation", "d": ["The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990059", "l": "fruit valve development", "d": ["The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034165", "l": "positive regulation of toll-like receptor 9 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0071222", "l": "cellular response to lipopolysaccharide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072294", "l": "specification of metanephric connecting tubule identity", "d": ["The process in which the connecting tubule of the metanephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003236", "l": "sinus venosus morphogenesis", "d": ["The process in which the sinus venosus is generated and organized. 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Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000286", "l": "receptor internalization involved in canonical Wnt signaling pathway", "d": ["A receptor internalization process that contributes to canonical Wnt signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090362", "l": "positive regulation of platelet-derived growth factor production", "d": ["Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060820", "l": "inactivation of X chromosome by heterochromatin formation", "d": ["Compensating for the two-fold variation in X-chromosome: autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007310", "l": "oocyte dorsal/ventral axis specification", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. 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The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036271", "l": "response to methylphenidate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904247", "l": "positive regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035116", "l": "embryonic hindlimb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036158", "l": "outer dynein arm assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904422", "l": "cellular response to D-galactosamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007441", "l": "anterior midgut (ectodermal) morphogenesis", "d": ["The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and 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"ic": "81.247621244257502", "identifiers": [{"i": "GO:0050761", "l": "depsipeptide metabolic process", "d": ["The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0007584", "l": "response to nutrient", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900947", "l": "regulation of isoprene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of isoprene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0018027", "l": "peptidyl-lysine dimethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000233", "l": "negative regulation of rRNA processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019879", "l": "peptidyl-thyronine biosynthetic process from peptidyl-tyrosine", "d": ["The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033480", "l": "UDP-D-galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine 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Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042628", "l": "mating plug formation", "d": ["The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904337", "l": "positive regulation of ductus arteriosus closure", "d": ["Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070093", "l": "negative regulation of glucagon secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018909", "l": "dodecyl sulfate metabolic process", "d": ["The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097291", "l": "renal phosphate ion absorption", "d": ["A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036046", "l": "protein demalonylation", "d": ["The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061371", "l": "determination of heart left/right asymmetry", "d": ["Determination of the asymmetric location of the heart with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0003170", "l": "heart valve development", "d": ["The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900189", "l": "positive regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036366", "l": "transforming growth factor beta3 activation", "d": ["The release of transforming growth factor beta 3 (TGF-beta3) from its latent state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904972", "l": "negative regulation of viral translation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905375", "l": "cellular response to homocysteine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0016241", "l": "regulation of macroautophagy", "d": ["Any process that modulates the frequency, rate or extent of macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043452", "l": "cellular alkyne metabolic process", "d": ["The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051558", "l": "phlobaphene metabolic process", "d": ["The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009828", "l": "plant-type cell wall loosening", "d": ["The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000040", "l": "regulation of planar cell polarity pathway involved in axis elongation", "d": ["Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071773", "l": "cellular response to BMP stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900736", "l": "regulation of phospholipase C-activating G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903512", "l": "phytanic acid metabolic process", "d": ["The chemical reactions and pathways involving phytanic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009965", "l": "leaf morphogenesis", "d": ["The process in which the anatomical structures of the leaf are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048485", "l": "sympathetic nervous system development", "d": ["The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. 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This occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061833", "l": "protein localization to tricellular tight junction", "d": ["A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010743", "l": "regulation of macrophage derived foam cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045162", "l": "clustering of voltage-gated sodium channels", "d": ["The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043305", "l": "negative regulation of mast cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of mast cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900354", "l": "regulation of methanofuran metabolic process", "d": ["Any process that modulates the frequency, rate or extent of methanofuran metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000563", "l": "positive regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034775", "l": "glutathione transmembrane transport", "d": ["A process in which glutathione is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060251", "l": "regulation of glial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of glial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.881614058838615", "identifiers": [{"i": "GO:0048609", "l": "multicellular organismal reproductive process", "d": ["The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.759065934317029", "identifiers": [{"i": "GO:0035725", "l": "sodium ion transmembrane transport", "d": ["A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060763", "l": "mammary duct terminal end bud growth", "d": ["The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009684", "l": "indoleacetic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070960", "l": "positive regulation of neutrophil mediated cytotoxicity", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000718", "l": "nucleotide-excision repair, DNA damage removal", "d": ["The removal of the oligonucleotide that contains the DNA damage. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048684", "l": "positive regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019930", "l": "cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid", "d": ["The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097113", "l": "AMPA glutamate receptor clustering", "d": ["The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098881", "l": "exocytic insertion of neurotransmitter receptor to plasma membrane", "d": ["The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048838", "l": "release of seed from dormancy", "d": ["The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070881", "l": "regulation of proline transport", "d": ["Any process that modulates the frequency, rate or extent of proline transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901170", "l": "naphthalene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of naphthalene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110090", "l": "positive regulation of hippocampal neuron apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045478", "l": "fusome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036172", "l": "thiamine salvage", "d": ["A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090518", "l": "L-arginine transmembrane import into vacuole", "d": ["The directed movement of L-arginine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.718318631034926", "identifiers": [{"i": "GO:0099046", "l": "clearance of foreign intracellular nucleic acids", "d": ["A defense process that protects an organism from DNA or RNA from an invading organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901202", "l": "negative regulation of extracellular matrix assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901758", "l": "butirosin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butirosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0101023", "l": "vascular endothelial cell proliferation", "d": ["The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0017148", "l": "negative regulation of translation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042746", "l": "circadian sleep/wake cycle, wakefulness", "d": ["The part of the circadian sleep/wake cycle where the organism is not asleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035457", "l": "cellular response to interferon-alpha", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0034086", "l": "maintenance of sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010507", "l": "negative regulation of autophagy", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001886", "l": "endothelial cell morphogenesis", "d": ["The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901802", "l": "1,5-anhydro-D-fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000930", "l": "regulation of cellobiose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellobiose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032661", "l": "regulation of interleukin-18 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-18 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000529", "l": "positive regulation of myeloid dendritic cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031652", "l": "positive regulation of heat generation", "d": ["Any process that activates or increases the rate or extent of heat generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006934", "l": "substrate-bound cell migration, adhesion receptor recycling", "d": ["The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905865", "l": "negative regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902754", "l": "positive regulation of renal amino acid absorption", "d": ["Any process that activates or increases the frequency, rate or extent of renal amino acid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0008354", "l": "germ cell migration", "d": ["The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018876", "l": "benzonitrile metabolic process", "d": ["The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098706", "l": "iron ion import across cell outer membrane", "d": ["The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0018212", "l": "peptidyl-tyrosine modification", "d": ["The modification of peptidyl-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0048898", "l": "anterior lateral line system development", "d": ["The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016254", "l": "preassembly of GPI anchor in ER membrane", "d": ["The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000372", "l": "Group I intron splicing", "d": ["The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:1903018", "l": "regulation of glycoprotein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of glycoprotein metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003430", "l": "growth plate cartilage chondrocyte growth", "d": ["The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032816", "l": "positive regulation of natural killer cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009397", "l": "folic acid-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046084", "l": "adenine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007485", "l": "imaginal disc-derived male genitalia development", "d": ["The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090337", "l": "regulation of formin-nucleated actin cable assembly", "d": ["Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903186", "l": "regulation of vitellogenesis", "d": ["Any process that modulates the frequency, rate or extent of vitellogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904573", "l": "regulation of selenocysteine insertion sequence binding", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060712", "l": "spongiotrophoblast layer development", "d": ["The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034635", "l": "glutathione transport", "d": ["The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033369", "l": "establishment of protein localization to mast cell secretory granule", "d": ["The directed movement of a protein to a location within a secretory granule in a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099000", "l": "viral genome ejection through host cell envelope, contractile tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032509", "l": "endosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046217", "l": "indole phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000438", "l": "negative regulation of monocyte extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006624", "l": "vacuolar protein processing", "d": ["Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016185", "l": "synaptic vesicle budding from presynaptic endocytic zone membrane", "d": ["Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006895", "l": "Golgi to endosome transport", "d": ["The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072098", "l": "anterior/posterior pattern specification involved in kidney development", "d": ["The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060092", "l": "regulation of synaptic transmission, glycinergic", "d": ["Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046006", "l": "regulation of activated T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of activated T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.391713369466018", "identifiers": [{"i": "GO:0015718", "l": "monocarboxylic acid transport", "d": ["The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060409", "l": "positive regulation of acetylcholine metabolic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048823", "l": "nucleate erythrocyte development", "d": ["The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002501", "l": "peptide antigen assembly with MHC protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061727", "l": "methylglyoxal catabolic process to lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009210", "l": "pyrimidine ribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010611", "l": "regulation of cardiac muscle hypertrophy", "d": ["Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140820", "l": "cytosol to Golgi apparatus transport", "d": ["The directed movement of substances from the cytosol into the Golgi apparatus of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0042176", "l": "regulation of protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.885542599809028", "identifiers": [{"i": "GO:0072697", "l": "protein localization to cell cortex", "d": ["A process in which a protein is transported to, or maintained in, the cell cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090463", "l": "intracellular lysine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of lysine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010982", "l": "regulation of high-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141042", "l": "symbiont-mediated cAMP intoxication of host cell", "d": ["The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071550", "l": "death-inducing signaling complex assembly", "d": ["A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006175", "l": "dATP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.115141650693708", "identifiers": [{"i": "GO:0006810", "l": "transport", "d": ["The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0009266", "l": "response to temperature stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050990", "l": "N-terminal protein amino acid carbamoylation", "d": ["The carbamoylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006501", "l": "C-terminal protein lipidation", "d": ["The covalent attachment of a lipid group to the carboxy-terminus of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106342", "l": "omega-hydroxyceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019433", "l": "triglyceride catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.082220929773669", "identifiers": [{"i": "GO:0006396", "l": "RNA processing", "d": ["Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014005", "l": "microglia development", "d": ["The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021749", "l": "ventral cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0033674", "l": "positive regulation of kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048462", "l": "carpel formation", "d": ["The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021975", "l": "pons reticulospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071787", "l": "endoplasmic reticulum tubular network formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.422285095499703", "identifiers": [{"i": "GO:0051937", "l": "catecholamine transport", "d": ["The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007562", "l": "eclosion", "d": ["The emergence of an adult insect from a pupa case."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0035883", "l": "enteroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061974", "l": "perichondral bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072286", "l": "metanephric connecting tubule development", "d": ["The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905234", "l": "cellular response to codeine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051894", "l": "positive regulation of focal adhesion assembly", "d": ["Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902917", "l": "positive regulation of mating projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mating projection assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090326", "l": "positive regulation of locomotion involved in locomotory behavior", "d": ["Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051344", "l": "negative regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001268", "l": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018228", "l": "peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010273", "l": "detoxification of copper ion", "d": ["Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060559", "l": "positive regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071258", "l": "cellular response to gravity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.095679833930788", "identifiers": [{"i": "GO:0071482", "l": "cellular response to light stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072024", "l": "macula densa development", "d": ["The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060319", "l": "primitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048700", "l": "acquisition of desiccation tolerance in seed", "d": ["The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0030490", "l": "maturation of SSU-rRNA", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060624", "l": "regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075308", "l": "negative regulation of conidium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072159", "l": "epithelial cell migration involved in proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007110", "l": "meiosis I cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051211", "l": "anisotropic cell growth", "d": ["The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0044272", "l": "sulfur compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000717", "l": "nucleotide-excision repair, DNA duplex unwinding", "d": ["The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060827", "l": "regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903722", "l": "regulation of centriole elongation", "d": ["Any process that modulates the frequency, rate or extent of centriole elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0060457", "l": "negative regulation of digestive system process", "d": ["Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031540", "l": "regulation of anthocyanin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010338", "l": "leaf formation", "d": ["The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048328", "l": "regulation of axial mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.517713470395833", "identifiers": [{"i": "GO:0045785", "l": "positive regulation of cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008594", "l": "photoreceptor cell morphogenesis", "d": ["The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046436", "l": "D-alanine metabolic process", "d": ["The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003183", "l": "mitral valve morphogenesis", "d": ["The process in which the structure of the mitral valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072292", "l": "epithelial cell migration involved in metanephric proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902943", "l": "positive regulation of voltage-gated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003252", "l": "negative regulation of cell proliferation involved in heart valve morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901251", "l": "positive regulation of lung goblet cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021728", "l": "inferior reticular formation development", "d": ["The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:1900046", "l": "regulation of hemostasis", "d": ["Any process that modulates the frequency, rate or extent of hemostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072104", "l": "glomerular capillary formation", "d": ["The process that gives rise to a glomerular capillary. 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This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0032388", "l": "positive regulation of intracellular transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098582", "l": "innate vocalization behavior", "d": ["A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900665", "l": "negative regulation of emodin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035711", "l": "T-helper 1 cell activation", "d": ["The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140077", "l": "positive regulation of lipoprotein transport", "d": ["Any process that activates or increases the rate or extent of lipoprotein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000991", "l": "regulation of galactomannan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of galactomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072031", "l": "proximal convoluted tubule segment 1 development", "d": ["The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006709", "l": "progesterone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900628", "l": "positive regulation of arugosin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034240", "l": "negative regulation of macrophage fusion", "d": ["Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.196521192641157", "identifiers": [{"i": "GO:0051983", "l": "regulation of chromosome segregation", "d": ["Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048782", "l": "negative regulation of cyanophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0086042", "l": "cardiac muscle cell-cardiac muscle cell adhesion", "d": ["The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061236", "l": "mesonephric comma-shaped body morphogenesis", "d": ["The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031509", "l": "subtelomeric heterochromatin formation", "d": ["The compaction of chromatin into heterochromatin at the subtelomeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009303", "l": "rRNA transcription", "d": ["The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060184", "l": "cell cycle switching", "d": ["The process in which a cell switches cell cycle mode."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150024", "l": "oxidised low-density lipoprotein particle clearance", "d": ["The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0099637", "l": "neurotransmitter receptor transport", "d": ["The directed movement of neurotransmitter receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051550", "l": "aurone metabolic process", "d": ["The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905004", "l": "picolinic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of picolinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046050", "l": "UMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010225", "l": "response to UV-C", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000369", "l": "regulation of clathrin-dependent endocytosis", "d": ["Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034409", "l": "ascospore wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021789", "l": "branchiomotor neuron axon guidance in branchial arch mesenchyme", "d": ["The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062234", "l": "platelet activating factor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033081", "l": "regulation of T cell differentiation in thymus", "d": ["Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051687", "l": "maintenance of spindle location", "d": ["Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0043935", "l": "sexual sporulation resulting in formation of a cellular spore", "d": ["The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062224", "l": "positive regulation of somatic muscle development", "d": ["Any process that increases the rate, frequency or extent of somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071691", "l": "cardiac muscle thin filament assembly", "d": ["The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000656", "l": "regulation of apolipoprotein binding", "d": ["Any process that modulates the frequency, rate or extent of apolipoprotein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044532", "l": "modulation of apoptotic process in another organism", "d": ["A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905162", "l": "regulation of phagosome maturation", "d": ["Any process that modulates the frequency, rate or extent of phagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070651", "l": "nonfunctional rRNA decay", "d": ["An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990689", "l": "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990218", "l": "positive regulation by symbiont of abscisic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018231", "l": "peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001189", "l": "negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.759065934317029", "identifiers": [{"i": "GO:0070085", "l": "glycosylation", "d": ["The covalent attachment and further modification of carbohydrate residues to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070955", "l": "negative regulation of neutrophil mediated killing of symbiont cell", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060368", "l": "regulation of Fc receptor mediated stimulatory signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150098", "l": "glial cell-neuron signaling", "d": ["Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904536", "l": "regulation of mitotic telomere tethering at nuclear periphery", "d": ["Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0099500", "l": "vesicle fusion to plasma membrane", "d": ["Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901730", "l": "monensin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monensin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045954", "l": "positive regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048105", "l": "establishment of body hair planar orientation", "d": ["Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015839", "l": "cadaverine transport", "d": ["The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060068", "l": "vagina development", "d": ["The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035910", "l": "ascending aorta morphogenesis", "d": ["The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019071", "l": "viral DNA cleavage involved in viral genome maturation", "d": ["The cleavage of viral DNA into singular functional units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901774", "l": "lincomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lincomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051218", "l": "tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0000725", "l": "recombinational repair", "d": ["A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044518", "l": "positive regulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075513", "l": "caveolin-mediated endocytosis of virus by host cell", "d": ["Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002837", "l": "regulation of immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of an immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035922", "l": "foramen ovale closure", "d": ["The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0051225", "l": "spindle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019666", "l": "nitrogenous compound fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071303", "l": "cellular response to vitamin B3", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060453", "l": "regulation of gastric acid secretion", "d": ["Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086072", "l": "AV node cell-bundle of His cell adhesion involved in cell communication", "d": ["The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900147", "l": "regulation of Schwann cell migration", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0060788", "l": "ectodermal placode formation", "d": ["The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015694", "l": "mercury ion transport", "d": ["The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901998", "l": "toxin transport", "d": ["The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010200", "l": "response to chitin", "d": ["A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904362", "l": "regulation of calcitonin secretion", "d": ["Any process that modulates the frequency, rate or extent of calcitonin secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003196", "l": "ventriculo bulbo valve formation", "d": ["The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0008585", "l": "female gonad development", "d": ["The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903049", "l": "negative regulation of acetylcholine-gated cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060794", "l": "leaflet morphogenesis", "d": ["The process in which the anatomical structures of the leaflet are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0021696", "l": "cerebellar cortex morphogenesis", "d": ["The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0031055", "l": "chromatin remodeling at centromere", "d": ["Dynamic structural changes in centromeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905283", "l": "negative regulation of epidermal growth factor receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902234", "l": "positive regulation of positive thymic T cell selection", "d": ["Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0044645", "l": "modulation of complement activation in another organism", "d": ["A process that modulates the frequency, rate or extent of complement activation in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000950", "l": "branched-chain amino acid catabolic process to alcohol via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000280", "l": "regulation of root development", "d": ["Any process that modulates the frequency, rate or extent of root development."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0070595", "l": "(1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099170", "l": "postsynaptic modulation of chemical synaptic transmission", "d": ["Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002345", "l": "peripheral B cell receptor editing", "d": ["The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140538", "l": "negative regulation of conjugation with zygote", "d": ["A process that prevents a zygote from fusing an additional cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075226", "l": "encysted zoospore germination", "d": ["The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900638", "l": "negative regulation of asperfuranone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900719", "l": "regulation of uterine smooth muscle relaxation", "d": ["Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110124", "l": "positive regulation of myotube cell migration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046276", "l": "methylgallate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072032", "l": "proximal convoluted tubule segment 2 development", "d": ["The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110056", "l": "positive regulation of actin filament annealing", "d": ["Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902347", "l": "response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1901378", "l": "organic heteropentacyclic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032966", "l": "negative regulation of collagen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042139", "l": "early meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010764", "l": "negative regulation of fibroblast migration", "d": ["Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003336", "l": "corneocyte desquamation", "d": ["The delamination process that results in the shedding of a corneocyte from the surface of the epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009767", "l": "photosynthetic electron transport chain", "d": ["A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015679", "l": "plasma membrane copper ion transport", "d": ["The directed movement of copper ions across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009999", "l": "negative regulation of auditory receptor cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0019320", "l": "hexose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001112", "l": "regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031582", "l": "replication fork arrest at rDNA repeats", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014915", "l": "regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction", "d": ["Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904388", "l": "negative regulation of ncRNA transcription associated with protein coding gene TSS/TES", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901258", "l": "positive regulation of macrophage colony-stimulating factor production", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0106072", "l": "negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006655", "l": "phosphatidylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.704486469205186", "identifiers": [{"i": "GO:1903046", "l": "meiotic cell cycle process", "d": ["A process that is part of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901931", "l": "alpha-copaene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-copaene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000089", "l": "mitotic metaphase", "d": ["The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000754", "l": "regulation of sphingomyelin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032109", "l": "positive regulation of response to nutrient levels", "d": ["Any process that activates or increases the frequency, rate or extent of a response to nutrient levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903108", "l": "regulation of mitochondrial transcription", "d": ["Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009737", "l": "response to abscisic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021972", "l": "corticospinal neuron axon guidance through spinal cord", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.702982456578013", "identifiers": [{"i": "GO:0042063", "l": "gliogenesis", "d": ["The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098921", "l": "retrograde trans-synaptic signaling by endocannabinoid", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990092", "l": "calcium-dependent self proteolysis", "d": ["The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075186", "l": "negative regulation of infection cushion formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006237", "l": "deoxycytidine salvage", "d": ["Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000982", "l": "positive regulation of inner ear receptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003233", "l": "bulbus arteriosus morphogenesis", "d": ["The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070368", "l": "positive regulation of hepatocyte differentiation", "d": ["Any process that activates or increases the rate or extent of hepatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0070302", "l": "regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.73516189500215", "identifiers": [{"i": "GO:0098657", "l": "import into cell", "d": ["The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007427", "l": "epithelial cell migration, open tracheal system", "d": ["The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900096", "l": "negative regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072327", "l": "vulval cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032106", "l": "positive regulation of response to extracellular stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to an extracellular stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990983", "l": "tRNA demethylation", "d": ["The removal of a methyl group from one or more residues within a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902084", "l": "fumagillin metabolic process", "d": ["The chemical reactions and pathways involving fumagillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046607", "l": "positive regulation of centrosome cycle", "d": ["Any process that activates or increases the frequency, rate or extent of the centrosome cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033007", "l": "negative regulation of mast cell activation involved in immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902008", "l": "negative regulation of toxin transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903919", "l": "negative regulation of actin filament severing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001915", "l": "negative regulation of T cell mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1903975", "l": "regulation of glial cell migration", "d": ["Any process that modulates the frequency, rate or extent of glial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905787", "l": "regulation of detection of mechanical stimulus involved in sensory perception of touch", "d": ["Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0014909", "l": "smooth muscle cell migration", "d": ["The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903180", "l": "negative regulation of dopamine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019556", "l": "histidine catabolic process to glutamate and formamide", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033397", "l": "zeatin metabolic process", "d": ["The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009131", "l": "pyrimidine nucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900949", "l": "positive regulation of isoprene biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0051602", "l": "response to electrical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036528", "l": "peptidyl-lysine deglycation", "d": ["The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003412", "l": "establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis", "d": ["The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140446", "l": "fumigermin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0061780", "l": "mitotic cohesin loading", "d": ["The protein localization to 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"biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075030", "l": "modulation of formation of symbiont germ tube hook structure for appressorium development", "d": ["Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007158", "l": "neuron cell-cell adhesion", "d": ["The attachment of a neuron to another cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0046466", "l": "membrane lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140754", "l": "reorganization of cellular membranes to establish viral sites of replication", "d": ["A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009213", "l": "pyrimidine deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000760", "l": "adaptation to pheromone regulating conjugation with mutual genetic exchange", "d": ["In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0009712", "l": "catechol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034757", "l": "negative regulation of iron ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051681", "l": "6-alpha-maltosylglucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046602", "l": "regulation of mitotic centrosome separation", "d": ["Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.45299868619928", "identifiers": [{"i": "GO:0014032", "l": "neural crest cell development", "d": ["The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032354", "l": "response to follicle-stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904873", "l": "negative regulation of telomerase RNA localization to Cajal body", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032752", "l": "positive regulation of interleukin-3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-3 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042373", "l": "vitamin K metabolic process", "d": ["The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042712", "l": "paternal behavior", "d": ["Male behaviors associated with the care and rearing offspring."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015814", "l": "p-aminobenzoyl-glutamate transport", "d": ["The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003185", "l": "sinoatrial valve morphogenesis", "d": ["The process in which the structure of the sinoatrial valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0008216", "l": "spermidine metabolic process", "d": ["The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071623", "l": "negative regulation of granulocyte chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. 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Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0031589", "l": "cell-substrate adhesion", "d": ["The attachment of a cell to the underlying substrate via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051308", "l": "male meiosis chromosome separation", "d": ["The process in which paired chromosomes are physically detached from each other during male meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002472", "l": "macrophage antigen processing and presentation", "d": ["The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071462", "l": "cellular response to water stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902313", "l": "positive regulation of copper ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060412", "l": "ventricular septum morphogenesis", "d": ["The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036236", "l": "acyl glucuronidation", "d": ["The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048725", "l": "cibarial fish-trap bristle development", "d": ["The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033467", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process", "d": ["The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034345", "l": "negative regulation of type III interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000925", "l": "negative regulation of cellodextrin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099642", "l": "retrograde axonal protein transport", "d": ["The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071931", "l": "positive regulation of transcription involved in G1/S transition of mitotic cell cycle", "d": ["Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045794", "l": "negative regulation of cell volume", "d": ["Any process that decreases cell volume."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085014", "l": "dormancy entry of symbiont in host", "d": ["Entry into a dormant state of the symbiont within the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904354", "l": "negative regulation of telomere capping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000973", "l": "regulation of pro-B cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pro-B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042340", "l": "keratan sulfate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035646", "l": "endosome to melanosome transport", "d": ["The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033481", "l": "galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061523", "l": "cilium disassembly", "d": ["A cellular process that results in the breakdown of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015787", "l": "UDP-glucuronic acid transmembrane transport", "d": ["The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098586", "l": "cellular response to virus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141006", "l": "piRNA-mediated retrotransposon silencing by heterochromatin formation", "d": ["A retrotransposon silencing mechanism in which a piRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902252", "l": "positive regulation of erythrocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904053", "l": "positive regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002793", "l": "positive regulation of peptide secretion", "d": ["Any process that activates or increases the frequency, rate, or extent of peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018001", "l": "N-terminal peptidyl-valine acetylation", "d": ["The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048579", "l": "negative regulation of long-day photoperiodism, flowering", "d": ["Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044577", "l": "xylose catabolic process to ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001044", "l": "regulation of integrin-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0070228", "l": "regulation of lymphocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046105", "l": "thymidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019491", "l": "ectoine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003213", "l": "cardiac right atrium morphogenesis", "d": ["The process in which the right cardiac atrium is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902068", "l": "regulation of sphingolipid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of sphingolipid signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002415", "l": "immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor", "d": ["The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0052541", "l": "plant-type cell wall cellulose metabolic process", "d": ["The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1904700", "l": "granulosa cell apoptotic process", "d": ["Any apoptotic process in a granulosa cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000655", "l": "negative regulation of cellular response to testosterone stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905613", "l": "regulation of developmental vegetative growth", "d": ["Any process that modulates the frequency, rate or extent of developmental vegetative growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.577298431659159", "identifiers": [{"i": "GO:0090596", "l": "sensory organ morphogenesis", "d": ["Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903948", "l": "negative regulation of atrial cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0061097", "l": "regulation of protein tyrosine kinase activity", "d": ["Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:1901663", "l": "quinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032529", "l": "follicle cell microvillus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001002", "l": "positive regulation of xylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0098721", "l": "uracil import across plasma membrane", "d": ["The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030167", "l": "proteoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902350", "l": "cellular response to chloroquine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034241", "l": "positive regulation of macrophage fusion", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002150", "l": "hypochlorous acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hypochlorous acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0001976", "l": "nervous system process involved in regulation of systemic arterial blood pressure", "d": ["The regulation of blood pressure mediated by detection of stimuli and a neurological response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090481", "l": "pyrimidine nucleotide-sugar transmembrane transport", "d": ["The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033490", "l": "cholesterol biosynthetic process via lathosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016061", "l": "regulation of light-activated channel activity", "d": ["Any process that modulates the frequency, rate or extent of light-activated channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905238", "l": "cellular response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008056", "l": "ocellus development", "d": ["The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002835", "l": "negative regulation of response to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000132", "l": "negative regulation of tyramine signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021524", "l": "visceral motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.027937138254075", "identifiers": [{"i": "GO:0034220", "l": "monoatomic ion transmembrane transport", "d": ["A process in which a monoatomic ion is transported across a membrane. 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Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901471", "l": "positive regulation of syringal lignin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046454", "l": "dimethylsilanediol metabolic process", "d": ["The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035833", "l": "berbamunine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.534642734314296", "identifiers": [{"i": "GO:0043543", "l": "protein acylation", "d": ["The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903060", "l": "negative regulation of protein lipidation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045588", "l": "positive regulation of gamma-delta T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990069", "l": "stomatal opening", "d": ["The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048292", "l": "isotype switching to IgD isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016191", "l": "synaptic vesicle uncoating", "d": ["The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0045055", "l": "regulated exocytosis", "d": ["A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010985", "l": "negative regulation of lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060887", "l": "limb epidermis development", "d": ["The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902961", "l": "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006393", "l": "termination of mitochondrial transcription", "d": ["A transcription termination process that completes the production of a primary mitochondrial transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:1904375", "l": "regulation of protein localization to cell periphery", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140208", "l": "apoptotic process in response to mitochondrial fragmentation", "d": ["Any apoptotic process that occurs as a result of mitochondrial fragmentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1902151", "l": "regulation of response to DNA integrity checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045635", "l": "negative regulation of melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902026", "l": "regulation of cartilage condensation", "d": ["Any process that modulates the frequency, rate or extent of cartilage condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106227", "l": "peptidyl-lysine glutarylation", "d": ["The glutarylation of a lysine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905749", "l": "regulation of endosome to plasma membrane protein transport", "d": ["Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0009615", "l": "response to virus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050979", "l": "magnetoreception by sensory perception of mechanical stimulus", "d": ["The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048463", "l": "carpel structural organization", "d": ["The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075713", "l": "establishment of integrated proviral latency", "d": ["A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003356", "l": "regulation of cilium beat frequency", "d": ["Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902213", "l": "positive regulation of prolactin signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "28.523909666045636", "identifiers": [{"i": "GO:0007275", "l": "multicellular organism development", "d": ["The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061407", "l": "positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031451", "l": "positive regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903590", "l": "regulation of lysozyme activity", "d": ["Any process that modulates the frequency, rate or extent of lysozyme activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090270", "l": "regulation of fibroblast growth factor production", "d": ["Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032055", "l": "negative regulation of translation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905095", "l": "negative regulation of apolipoprotein A-I-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905579", "l": "negative regulation of ERBB3 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060218", "l": "hematopoietic stem cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0051353", "l": "positive regulation of oxidoreductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0032060", "l": "bleb assembly", "d": ["The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036183", "l": "asperthecin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045653", "l": "negative regulation of megakaryocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043314", "l": "negative regulation of neutrophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of neutrophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051391", "l": "tRNA acetylation", "d": ["The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009689", "l": "induction of phytoalexin biosynthetic process", "d": ["The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061516", "l": "monocyte proliferation", "d": ["The expansion of a monocyte population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030583", "l": "myxococcal fruiting body development", "d": ["The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.323668158560849", "identifiers": [{"i": "GO:0007548", "l": "sex differentiation", "d": ["The establishment of the sex of an organism by physical differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018889", "l": "2-chloro-N-isopropylacetanilide metabolic process", "d": ["The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018923", "l": "limonene metabolic process", "d": ["The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039634", "l": "killing by virus of host cell during superinfection exclusion", "d": ["The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905766", "l": "positive regulation of protection from non-homologous end joining at telomere", "d": ["Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019604", "l": "toluene oxidation to catechol", "d": ["The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032825", "l": "positive regulation of natural killer cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048212", "l": "Golgi vesicle uncoating", "d": ["The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033585", "l": "L-phenylalanine biosynthetic process from chorismate via phenylpyruvate", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061867", "l": "establishment of mitotic spindle asymmetry", "d": ["The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001682", "l": "tRNA 5'-leader removal", "d": ["Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000175", "l": "negative regulation of pro-T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110114", "l": "negative regulation of lipid transporter activity", "d": ["Any process that decreases the frequency, rate, or extent of lipid transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052168", "l": "modulation by symbiont of defense-related host calcium-dependent protein kinase pathway", "d": ["Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051165", "l": "2,5-dihydroxypyridine metabolic process", "d": ["The chemical reactions and pathways involving 2,5-dihydroxypyridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016111", "l": "polyterpenoid metabolic process", "d": ["The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0039503", "l": "suppression by virus of host innate immune response", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019361", "l": "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090324", "l": "negative regulation of oxidative phosphorylation", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045953", "l": "negative regulation of natural killer cell mediated cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010051", "l": "xylem and phloem pattern formation", "d": ["The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900944", "l": "regulation of isoprene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of isoprene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0051310", "l": "metaphase chromosome alignment", "d": ["A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905384", "l": "regulation of protein localization to presynapse", "d": ["Any process that modulates the frequency, rate or extent of protein localization to presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071170", "l": "site-specific DNA replication termination", "d": ["A DNA replication termination process that takes place at a specific termination site."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009212", "l": "pyrimidine deoxyribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0032352", "l": "positive regulation of hormone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006187", "l": "dGTP biosynthetic process from dGDP", "d": ["The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0009886", "l": "post-embryonic animal morphogenesis", "d": ["The process, occurring after animal embryonic development, by which anatomical structures are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018003", "l": "peptidyl-lysine N6-acetylation", "d": ["The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000883", "l": "positive regulation of starch catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of starch catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903177", "l": "negative regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0072665", "l": "protein localization to vacuole", "d": ["A process in which a protein is transported to, or maintained at, a location in a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000972", "l": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006808", "l": "regulation of nitrogen utilization", "d": ["Any process that modulates the frequency, rate or extent of nitrogen utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045338", "l": "farnesyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009859", "l": "pollen hydration", "d": ["The process in which water is taken up by pollen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904551", "l": "cellular response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043113", "l": "receptor clustering", "d": ["The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901750", "l": "leukotriene D4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene D4."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.820827815612489", "identifiers": [{"i": "GO:0001957", "l": "intramembranous ossification", "d": ["Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904113", "l": "negative regulation of muscle filament sliding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060767", "l": "epithelial cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903355", "l": "negative regulation of distal tip cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "16.126783056119848", "identifiers": [{"i": "GO:0009987", "l": "cellular process", "d": ["Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990810", "l": "microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019620", "l": "aerobic benzoate metabolic process", "d": ["The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031627", "l": "telomeric loop formation", "d": ["The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018990", "l": "ecdysis, chitin-based cuticle", "d": ["The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000544", "l": "regulation of endothelial cell chemotaxis to fibroblast growth factor", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003424", "l": "establishment of cell polarity involved in growth plate cartilage chondrocyte division", "d": ["The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905829", "l": "negative regulation of prostaglandin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900507", "l": "negative regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018359", "l": "protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine", "d": ["The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120174", "l": "stress-induced homeostatically regulated protein degradation pathway", "d": ["A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002205", "l": "somatic hypermutation of immunoglobulin genes involved in immune response", "d": ["Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904443", "l": "positive regulation of thyroid gland epithelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001897", "l": "cytolysis by symbiont of host cells", "d": ["The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0022615", "l": "protein to membrane docking", "d": ["The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080110", "l": "sporopollenin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072489", "l": "methylammonium transmembrane transport", "d": ["The process in which methylammonium is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140450", "l": "protein targeting to Golgi apparatus", "d": ["The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0045491", "l": "xylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098912", "l": "membrane depolarization during atrial cardiac muscle cell action potential", "d": ["The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021570", "l": "rhombomere 4 development", "d": ["The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009206", "l": "purine ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046256", "l": "2,4,6-trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0008037", "l": "cell recognition", "d": ["The process in which a cell in an organism interprets its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010574", "l": "regulation of vascular endothelial growth factor production", "d": ["Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060945", "l": "cardiac neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003294", "l": "atrial ventricular junction remodeling", "d": ["The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002789", "l": "negative regulation of antifungal peptide production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903270", "l": "regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904910", "l": "regulation of establishment of RNA localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0106074", "l": "aminoacyl-tRNA metabolism involved in translational fidelity", "d": ["Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061055", "l": "myotome development", "d": ["The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0043200", "l": "response to amino acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900631", "l": "tridecane metabolic process", "d": ["The chemical reactions and pathways involving tridecane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097284", "l": "hepatocyte apoptotic process", "d": ["Any apoptotic process in a hepatocyte, the main structural component of the liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046127", "l": "pyrimidine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071945", "l": "regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed", "d": ["A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900367", "l": "positive regulation of defense response to insect", "d": ["Any process that activates or increases the frequency, rate or extent of defense response to insect."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022035", "l": "rhombomere cell migration", "d": ["The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901415", "l": "positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060885", "l": "clearance of cells from fusion plate by apoptotic process", "d": ["Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003087", "l": "positive regulation of the force of heart contraction by neuronal epinephrine", "d": ["The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905257", "l": "positive regulation of RNA binding transcription factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052700", "l": "ergothioneine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0042403", "l": "thyroid hormone metabolic process", "d": ["The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902197", "l": "isovaleryl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016539", "l": "intein-mediated protein splicing", "d": ["The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018915", "l": "ethylbenzene metabolic process", "d": ["The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0015855", "l": "pyrimidine nucleobase transport", "d": ["The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0085033", "l": "induction of host canonical NF-kappaB signal transduction", "d": ["A process that initiates, promotes, or enhances a canonical NF-kappaB-mediated signaling cascade. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032293", "l": "non-myelinated axon ensheathment in central nervous system", "d": ["The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0071326", "l": "cellular response to monosaccharide stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900666", "l": "positive regulation of emodin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000936", "l": "regulation of cellotriose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellotriose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099630", "l": "postsynaptic neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042350", "l": "GDP-L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034489", "l": "neutral amino acid transmembrane export from vacuole", "d": ["The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042494", "l": "detection of bacterial lipoprotein", "d": ["The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904401", "l": "cellular response to Thyroid stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0090493", "l": "catecholamine uptake", "d": ["The directed movement of catecholamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904114", "l": "positive regulation of muscle filament sliding", "d": ["Any process that activates or increases the frequency, rate or extent of muscle filament sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903657", "l": "negative regulation of type IV pilus biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0001754", "l": "eye photoreceptor cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990168", "l": "protein K33-linked deubiquitination", "d": ["A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035383", "l": "thioester metabolic process", "d": ["The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043100", "l": "pyrimidine nucleobase salvage", "d": ["Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905601", "l": "negative regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0036508", "l": "protein alpha-1,2-demannosylation", "d": ["The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901836", "l": "regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043979", "l": "histone H2B-K5 acetylation", "d": ["The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905913", "l": "negative regulation of calcium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903428", "l": "positive regulation of reactive oxygen species biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140300", "l": "serine import into mitochondrion", "d": ["The process in which serine is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902757", "l": "bis(molybdopterin guanine dinucleotide)molybdenum metabolic process", "d": ["The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035875", "l": "maintenance of meiotic sister chromatid cohesion, centromeric", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0046864", "l": "isoprenoid transport", "d": ["The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015895", "l": "alkane transport", "d": ["The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000032", "l": "regulation of secondary shoot formation", "d": ["Any process that modulates the frequency, rate or extent of secondary shoot formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006488", "l": "dolichol-linked oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042675", "l": "compound eye cone cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009215", "l": "purine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060570", "l": "negative regulation of peptide hormone processing", "d": ["Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0030168", "l": "platelet activation", "d": ["A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070794", "l": "negative regulation of conidiophore development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900790", "l": "pseurotin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pseurotin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043158", "l": "heterocyst development", "d": ["The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039560", "l": "disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity", "d": ["Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:1903463", "l": "regulation of mitotic cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0097746", "l": "blood vessel diameter maintenance", "d": ["Any process that modulates the diameter of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030587", "l": "sorocarp development", "d": ["The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902192", "l": "2-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031125", "l": "rRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060643", "l": "epithelial cell differentiation involved in mammary gland bud morphogenesis", "d": ["The process in which a cell of the mammary placode becomes a cell of the mammary gland bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106303", "l": "mannogen metabolic process", "d": ["The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000636", "l": "positive regulation of primary miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of primary microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072158", "l": "proximal tubule morphogenesis", "d": ["The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990432", "l": "siRNA 3'-end processing", "d": ["The process of forming the mature 3' end of a siRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.903751730683766", "identifiers": [{"i": "GO:0035295", "l": "tube development", "d": ["The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006613", "l": "cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006044", "l": "N-acetylglucosamine metabolic process", "d": ["The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033693", "l": "neurofilament bundle assembly", "d": ["The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905364", "l": "regulation of endosomal vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of endosomal vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901899", "l": "positive regulation of relaxation of cardiac muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045792", "l": "negative regulation of cell size", "d": ["Any process that reduces cell size."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000430", "l": "regulation of transcription from RNA polymerase II promoter by glucose", "d": ["Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019273", "l": "L-alanine biosynthetic process via ornithine", "d": ["The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046384", "l": "2-deoxyribose 1-phosphate metabolic process", "d": ["The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072743", "l": "cellular response to erythromycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061112", "l": "negative regulation of bud outgrowth involved in lung branching", "d": ["Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903244", "l": "positive regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110026", "l": "regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044563", "l": "envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015877", "l": "biopterin transport", "d": ["The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030032", "l": "lamellipodium assembly", "d": ["Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:2000272", "l": "negative regulation of signaling receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905397", "l": "activated CD8-positive, alpha-beta T cell apoptotic process", "d": ["Any apoptotic process in an activated CD8-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044860", "l": "protein localization to plasma membrane raft", "d": ["A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0002011", "l": "morphogenesis of an epithelial sheet", "d": ["The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039554", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048024", "l": "regulation of mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000744", "l": "positive regulation of anterior head development", "d": ["Any process that activates or increases the frequency, rate or extent of anterior head development."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0002661", "l": "regulation of B cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106233", "l": "glycosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0071621", "l": "granulocyte chemotaxis", "d": ["The movement of a granulocyte in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021514", "l": "ventral spinal cord interneuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014865", "l": "detection of activity", "d": ["The series of events in which an activity stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.710521892834109", "identifiers": [{"i": "GO:0010720", "l": "positive regulation of cell development", "d": ["Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098596", "l": "imitative learning", "d": ["Learning in which new behaviors are acquired through imitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042416", "l": "dopamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075524", "l": "ribosomal skipping", "d": ["A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031337", "l": "positive regulation of sulfur amino acid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072399", "l": "response to cytokinesis checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015901", "l": "cycloheximide transport", "d": ["The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014004", "l": "microglia differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035799", "l": "ureter maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032679", "l": "regulation of TRAIL production", "d": ["Any process that modulates the frequency, rate, or extent of TRAIL production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070936", "l": "protein K48-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009835", "l": "fruit ripening", "d": ["An developmental maturation process that has as participant a fruit. 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An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033122", "l": "negative regulation of purine nucleotide catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071643", "l": "regulation of chemokine (C-C motif) ligand 4 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904029", "l": "regulation of cyclin-dependent protein kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900358", "l": "negative regulation of nigerotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0150116", "l": "regulation of cell-substrate junction organization", "d": ["Any process that modulates the frequency, rate or extent of cell-substrate junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0090183", "l": "regulation of kidney development", "d": ["Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002866", "l": "positive regulation of acute inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035610", "l": "protein side chain deglutamylation", "d": ["The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001075", "l": "negative regulation of metanephric ureteric bud development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905646", "l": "positive regulation of FACT complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of FACT complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090124", "l": "N-4 methylation of cytosine", "d": ["The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901846", "l": "positive regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006264", "l": "mitochondrial DNA replication", "d": ["The process in which new strands of DNA are synthesized in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045325", "l": "peptidyl-tryptophan hydroxylation", "d": ["The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006771", "l": "riboflavin metabolic process", "d": ["The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0048563", "l": "post-embryonic animal organ morphogenesis", "d": ["Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071786", "l": "endoplasmic reticulum tubular network organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048837", "l": "sorocarp sorus development", "d": ["The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061072", "l": "iris morphogenesis", "d": ["The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010479", "l": "stele development", "d": ["The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071294", "l": "cellular response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098746", "l": "fast, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003150", "l": "muscular septum morphogenesis", "d": ["The process in which the muscular septum is generated and organized. 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An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009590", "l": "detection of gravity", "d": ["The series of events in which a gravitational stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032900", "l": "negative regulation of neurotrophin production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904963", "l": "regulation of phytol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phytol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0007160", "l": "cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904074", "l": "negative regulation of trophectodermal cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071000", "l": "response to magnetism", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902256", "l": "regulation of apoptotic process involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046878", "l": "positive regulation of saliva secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of saliva."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061102", "l": "stomach neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900772", "l": "fumitremorgin B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046155", "l": "rhodopsin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055093", "l": "response to hyperoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007614", "l": "short-term memory", "d": ["The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.867130974462597", "identifiers": [{"i": "GO:0009966", "l": "regulation of signal transduction", "d": ["Any process that modulates the frequency, rate or extent of signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0022618", "l": "protein-RNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060282", "l": "positive regulation of oocyte development", "d": ["Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901696", "l": "cannabinoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cannabinoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900344", "l": "positive regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002724", "l": "regulation of T cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of T cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0099601", "l": "regulation of neurotransmitter receptor activity", "d": ["Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009233", "l": "menaquinone metabolic process", "d": ["The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043483", "l": "anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light", "d": ["The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075025", "l": "initiation of appressorium formation", "d": ["The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043569", "l": "negative regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904119", "l": "negative regulation of otic vesicle morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140009", "l": "L-aspartate import across plasma membrane", "d": ["The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032534", "l": "regulation of microvillus assembly", "d": ["A process that modulates the formation of a microvillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.973714123956164", "identifiers": [{"i": "GO:2001141", "l": "regulation of RNA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of RNA biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140291", "l": "peptidyl-glutamate ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylglutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002389", "l": "tolerance induction in Peyer's patch", "d": ["Tolerance induction taking place in the Peyer's patches."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901092", "l": "positive regulation of protein tetramerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein tetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:1905819", "l": "negative regulation of chromosome separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019665", "l": "anaerobic amino acid catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071313", "l": "cellular response to caffeine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050873", "l": "brown fat cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905677", "l": "regulation of adaptive immune effector response", "d": ["Any process that modulates the frequency, rate or extent of adaptive immune effector response."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.702255451054775", "identifiers": [{"i": "GO:0006793", "l": "phosphorus metabolic process", "d": ["The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002844", "l": "negative regulation of tolerance induction to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046372", "l": "D-arabinose metabolic process", "d": ["The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0008535", "l": "respiratory chain complex IV assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003201", "l": "epithelial to mesenchymal transition involved in coronary vasculature morphogenesis", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034092", "l": "negative regulation of maintenance of sister chromatid cohesion", "d": ["Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043577", "l": "chemotropism", "d": ["The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006363", "l": "termination of RNA polymerase I transcription", "d": ["A transcription termination process that completes the production of a ribosomal RNA transcript. RNAP I termination requires binding of a terminator protein to specific sequences downstream of the transcription unit."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042052", "l": "rhabdomere development", "d": ["The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034392", "l": "negative regulation of smooth muscle cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901067", "l": "ferulate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ferulate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901444", "l": "positive regulation of response to furfural", "d": ["Any process that activates or increases the frequency, rate or extent of response to furfural."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010660", "l": "regulation of muscle cell apoptotic process", "d": ["Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075508", "l": "entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm", "d": ["Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900431", "l": "regulation of filamentous growth of a population of unicellular organisms in response to heat", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098779", "l": "positive regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060907", "l": "positive regulation of macrophage cytokine production", "d": ["Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048132", "l": "female germ-line stem cell asymmetric division", "d": ["The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042066", "l": "perineurial glial growth", "d": ["Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000523", "l": "regulation of T cell costimulation", "d": ["Any process that modulates the frequency, rate or extent of T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061772", "l": "xenobiotic transport across blood-nerve barrier", "d": ["The directed movement of a xenobiotic through the blood-nerve barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.945349939901874", "identifiers": [{"i": "GO:0010948", "l": "negative regulation of cell cycle process", "d": ["Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000570", "l": "positive regulation of T-helper 2 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060169", "l": "negative regulation of adenosine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014720", "l": "tonic skeletal muscle contraction", "d": ["A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.697407499888214", "identifiers": [{"i": "GO:0019216", "l": "regulation of lipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032483", "l": "regulation of Rab protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rab protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0019319", "l": "hexose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030204", "l": "chondroitin sulfate metabolic process", "d": ["The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0106056", "l": "regulation of calcineurin-mediated signaling", "d": ["Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070760", "l": "positive regulation of interleukin-35-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032243", "l": "negative regulation of nucleoside transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0033028", "l": "myeloid cell apoptotic process", "d": ["Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032681", "l": "regulation of lymphotoxin A production", "d": ["Any process that modulates the frequency, rate, or extent of lymphotoxin A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001314", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0071988", "l": "protein localization to spindle pole body", "d": ["A process in which a protein is transported to, or maintained at, the spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036277", "l": "response to anticonvulsant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061094", "l": "regulation of turning behavior involved in mating", "d": ["Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.095679833930788", "identifiers": [{"i": "GO:0120251", "l": "hydrocarbon biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061753", "l": "substrate localization to autophagosome", "d": ["The localization process by which an autophagic substrate is delivered to a forming autophagosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072658", "l": "maintenance of protein location in membrane", "d": ["Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051896", "l": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0060113", "l": "inner ear receptor cell differentiation", "d": ["The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042045", "l": "epithelial fluid transport", "d": ["The directed movement of fluid across epithelia."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015700", "l": "arsenite transport", "d": ["The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060528", "l": "secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development", "d": ["The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903816", "l": "positive regulation of collecting lymphatic vessel constriction", "d": ["Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900399", "l": "positive regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002585", "l": "positive regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000394", "l": "positive regulation of lamellipodium morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001799", "l": "regulation of type IIb hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006756", "l": "AMP phosphorylation", "d": ["The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0051349", "l": "positive regulation of lyase activity", "d": ["Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035388", "l": "positive regulation of Roundabout signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090035", "l": "positive regulation of chaperone-mediated protein complex assembly", "d": ["Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051611", "l": "regulation of serotonin uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090139", "l": "mitochondrial chromosome packaging", "d": ["A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002803", "l": "positive regulation of antibacterial peptide production", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.388382942757389", "identifiers": [{"i": "GO:0051651", "l": "maintenance of location in cell", "d": ["Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0007619", "l": "courtship behavior", "d": ["The behavior of an organism for the purpose of attracting sexual partners."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0019359", "l": "nicotinamide nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.16748027341059", "identifiers": [{"i": "GO:0034765", "l": "regulation of monoatomic ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000378", "l": "negative regulation of reactive oxygen species metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061961", "l": "positive regulation of heme oxygenase activity", "d": ["Any process that activates or increases the frequency or rate of heme oxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075507", "l": "entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome", "d": ["Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0016137", "l": "glycoside metabolic process", "d": ["The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903024", "l": "positive regulation of ascospore-type prospore membrane formation", "d": ["Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021599", "l": "abducens nerve formation", "d": ["The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071946", "l": "cis-acting DNA replication termination", "d": ["A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071378", "l": "cellular response to growth hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060451", "l": "negative regulation of hindgut contraction", "d": ["Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903779", "l": "regulation of cardiac conduction", "d": ["Any process that modulates the frequency, rate or extent of cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071364", "l": "cellular response to epidermal growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003386", "l": "amphid sensory organ development", "d": ["The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.528458322397171", "identifiers": [{"i": "GO:1903522", "l": "regulation of blood circulation", "d": ["Any process that modulates the frequency, rate or extent of blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900491", "l": "regulation of [4Fe-4S] cluster assembly", "d": ["Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000565", "l": "negative regulation of CD8-positive, alpha-beta T cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0061525", "l": "hindgut development", "d": ["The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0048320", "l": "axial mesoderm formation", "d": ["The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061414", "l": "positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034491", "l": "neutral amino acid transmembrane import into vacuole", "d": ["The directed movement of neutral amino acids into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990692", "l": "trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006097", "l": "glyoxylate cycle", "d": ["A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071320", "l": "cellular response to cAMP", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0019585", "l": "glucuronate metabolic process", "d": ["The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015014", "l": "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000157", "l": "negative regulation of ubiquitin-specific protease activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021577", "l": "hindbrain structural organization", "d": ["The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0009948", "l": "anterior/posterior axis specification", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901957", "l": "regulation of cutin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cutin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019356", "l": "nicotinate nucleotide biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901818", "l": "beta-zeacarotene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000869", "l": "positive regulation of estrone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048931", "l": "posterior lateral line nerve glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022036", "l": "rhombomere cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902871", "l": "positive regulation of amacrine cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030844", "l": "positive regulation of intermediate filament depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002371", "l": "dendritic cell cytokine production", "d": ["Any process that contributes to cytokine production by a dendritic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002566", "l": "somatic diversification of immune receptors via somatic mutation", "d": ["The process in which immune receptor genes are diversified through somatic mutation."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.836170798622533", "identifiers": [{"i": "GO:0050863", "l": "regulation of T cell activation", "d": ["Any process that modulates the frequency, rate or extent of T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002662", "l": "negative regulation of B cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031120", "l": "snRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019677", "l": "NAD catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009153", "l": "purine deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900897", "l": "negative regulation of heptadecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0060740", "l": "prostate gland epithelium morphogenesis", "d": ["The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000996", "l": "positive regulation of mannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080051", "l": "cutin transport", "d": ["The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110104", "l": "mRNA alternative polyadenylation", "d": ["The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044486", "l": "modulation of transmission of nerve impulse in another organism", "d": ["The process in which an organism effects a change in the transmission of a nerve impulse in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901057", "l": "trimethylenediamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trimethylenediamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007028", "l": "cytoplasm organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071999", "l": "extracellular polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150023", "l": "apical dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019490", "l": "2-aminobenzenesulfonate desulfonation", "d": ["The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002025", "l": "norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "d": ["A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051683", "l": "establishment of Golgi localization", "d": ["The directed movement of the Golgi to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007317", "l": "regulation of pole plasm oskar mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0098760", "l": "response to interleukin-7", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014861", "l": "regulation of skeletal muscle contraction via regulation of action potential", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902182", "l": "shoot apical meristem development", "d": ["The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:1901292", "l": "nucleoside phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0055094", "l": "response to lipoprotein particle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018911", "l": "1,2,4-trichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060931", "l": "sinoatrial node cell development", "d": ["The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106121", "l": "positive regulation of cobalamin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031581", "l": "hemidesmosome assembly", "d": ["Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904989", "l": "positive regulation of endothelial cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051114", "l": "peptidyl-histidine uridylylation", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070174", "l": "negative regulation of enamel mineralization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042874", "l": "D-glucuronate transmembrane transport", "d": ["The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904000", "l": "positive regulation of eating behavior", "d": ["Any process that activates or increases the frequency, rate or extent of eating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010936", "l": "negative regulation of macrophage cytokine production", "d": ["Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904320", "l": "positive regulation of smooth muscle contraction involved in micturition", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000316", "l": "sulfite transport", "d": ["The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021601", "l": "abducens nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900204", "l": "apoptotic process involved in metanephric collecting duct development", "d": ["Any apoptotic process that is involved in metanephric collecting duct development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098814", "l": "spontaneous synaptic transmission", "d": ["The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0048581", "l": "negative regulation of post-embryonic development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061948", "l": "premature acrosome loss", "d": ["The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036168", "l": "filamentous growth of a population of unicellular organisms in response to heat", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903324", "l": "negative regulation of snoRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.47237971304007", "identifiers": [{"i": "GO:0019724", "l": "B cell mediated immunity", "d": ["Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0098630", "l": "aggregation of unicellular organisms", "d": ["The clustering together of unicellular organisms in suspension form aggregates."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.296567419392041", "identifiers": [{"i": "GO:1901361", "l": "organic cyclic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic cyclic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070058", "l": "tRNA gene clustering", "d": ["The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002434", "l": "immune complex clearance", "d": ["A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0048884", "l": "neuromast development", "d": ["The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902987", "l": "negative regulation of lysine biosynthetic process via aminoadipic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.022889380119096", "identifiers": [{"i": "GO:0002694", "l": "regulation of leukocyte activation", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0072047", "l": "proximal/distal pattern formation involved in nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. 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An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050821", "l": "protein stabilization", "d": ["Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010024", "l": "phytochromobilin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015958", "l": "bis(5'-nucleosidyl) oligophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' 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"identifiers": [{"i": "GO:1990277", "l": "parasexual reproduction with cellular fusion", "d": ["A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0055070", "l": "copper ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032653", "l": "regulation of interleukin-10 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-10 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046058", "l": "cAMP metabolic process", "d": ["The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]} {"type": 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"identifiers": [{"i": "GO:0090081", "l": "regulation of heart induction by regulation of canonical Wnt signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006901", "l": "vesicle coating", "d": ["A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071831", "l": "intermediate-density lipoprotein particle clearance", "d": ["The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021936", "l": "regulation of cerebellar granule cell precursor proliferation", "d": ["The process that modulates the frequency, rate or extent of granule cell precursor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902381", "l": "11-oxo-beta-amyrin metabolic process", "d": ["The chemical reactions and pathways involving 11-oxo-beta-amyrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052094", "l": "formation of haustorium for nutrient acquisition", "d": ["The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903799", "l": "negative regulation of miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042211", "l": "dimethylsilanediol catabolic process", "d": ["The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120175", "l": "regulation of torso signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the torso signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903596", "l": "regulation of gap junction assembly", "d": ["Any process that modulates the frequency, rate or extent of gap junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046760", "l": "viral budding from Golgi membrane", "d": ["A viral budding that starts with formation of a membrane curvature in the host Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000858", "l": "regulation of 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{"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090162", "l": "establishment of epithelial cell polarity", "d": ["The specification and formation of anisotropic intracellular organization of an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018294", "l": "protein-FAD linkage via S-(8alpha-FAD)-L-cysteine", "d": ["The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0060258", "l": "negative regulation of filamentous growth", "d": ["Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:2000769", "l": "regulation of establishment or maintenance of cell 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A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. 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breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070571", "l": "negative regulation of neuron projection regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990000", "l": "amyloid fibril formation", "d": ["The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035889", "l": "otolith tethering", "d": ["The attachment of a developing otolith to the kinocilia of tether cells in the inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000350", "l": "positive regulation of CD40 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902428", "l": "negative regulation of water channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905099", "l": "positive regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.16748027341059", "identifiers": [{"i": "GO:0046165", "l": "alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090014", "l": "leaflet formation", "d": ["The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904412", "l": "regulation of cardiac ventricle development", "d": ["Any process that modulates the frequency, rate or extent of cardiac ventricle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:1902533", "l": "positive regulation of intracellular signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060257", "l": "negative regulation of flocculation", "d": ["Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000099", "l": "regulation of establishment or maintenance of bipolar cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006791", "l": "sulfur utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097496", "l": "blood vessel lumen ensheathment", "d": ["A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000562", "l": "negative regulation of CD4-positive, alpha-beta T cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052785", "l": "cellulose catabolism by endo-processive cellulases", "d": ["The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031289", "l": "actin phosphorylation", "d": ["The transfer of one or more phosphate groups to an actin molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075139", "l": "response to host iron concentration", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052074", "l": "positive regulation by symbiont of host salicylic acid-mediated defense response", "d": ["Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905505", "l": "positive regulation of motile cilium assembly", "d": ["Any process that activates or increases the frequency, rate or extent of motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021835", "l": "chemoattraction involved in embryonic olfactory bulb interneuron precursor migration", "d": ["The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060176", "l": "regulation of aggregation involved in sorocarp development", "d": ["Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048373", "l": "lateral mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009848", "l": "indoleacetic acid biosynthetic process via tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905012", "l": "regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060717", "l": "chorion development", "d": ["The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0009448", "l": "gamma-aminobutyric acid metabolic process", "d": ["The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002691", "l": "regulation of cellular extravasation", "d": ["Any process that modulates the frequency, rate, or extent of cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036276", "l": "response to antidepressant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0050807", "l": "regulation of synapse organization", "d": ["Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052021", "l": "modulation by symbiont of ethylene levels in host", "d": ["The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032662", "l": "regulation of interleukin-19 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-19 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905701", "l": "positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.310881285254894", "identifiers": [{"i": "GO:0050881", "l": "musculoskeletal movement", "d": ["The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042864", "l": "pyochelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033660", "l": "suppression by symbiont of host resistance gene-dependent defense response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901939", "l": "(-)-exo-alpha-bergamotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021723", "l": "medullary reticular formation development", "d": ["The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036289", "l": "peptidyl-serine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0099517", "l": "synaptic vesicle transport along microtubule", "d": ["The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033520", "l": "phytol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075248", "l": "regulation of aeciospore formation", "d": ["Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901723", "l": "negative regulation of cell proliferation involved in kidney development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032228", "l": "regulation of synaptic transmission, GABAergic", "d": ["Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010661", "l": "positive regulation of muscle cell apoptotic process", "d": ["Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046512", "l": "sphingosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0051208", "l": "sequestering of calcium ion", "d": ["The process of binding or confining calcium ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034300", "l": "sporangiospore formation", "d": ["The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046147", "l": "tetrahydrobiopterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070075", "l": "tear secretion", "d": ["The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007375", "l": "anterior midgut invagination", "d": ["Internalization of the anterior midgut into the interior of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090271", "l": "positive regulation of fibroblast growth factor production", "d": ["Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0007432", "l": "salivary gland boundary specification", "d": ["Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106112", "l": "negative regulation of mitotic cohesin ssDNA (lagging strand) loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140404", "l": "effector-mediated perturbation of host innate immune response by symbiont", "d": ["A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048807", "l": "female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039648", "l": "modulation by symbiont of host protein ubiquitination", "d": ["Any process by which a symbiont increases or decreases ubiquitination of target proteins of a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903574", "l": "negative regulation of cellular response to amino acid starvation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904055", "l": "negative regulation of cholangiocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021677", "l": "rhombomere 8 formation", "d": ["The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042690", "l": "negative regulation of crystal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1901679", "l": "nucleotide transmembrane transport", "d": ["The directed movement of nucleotide across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060014", "l": "granulosa cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043097", "l": "pyrimidine nucleoside salvage", "d": ["Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007026", "l": "negative regulation of microtubule depolymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006715", "l": "farnesol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0006406", "l": "mRNA export from nucleus", "d": ["The directed movement of mRNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018402", "l": "protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051763", "l": "sesquiterpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0043462", "l": "regulation of ATP-dependent activity", "d": ["Any process that modulates the rate of an ATP-dependent activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075250", "l": "negative regulation of aeciospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018921", "l": "3-hydroxybenzyl alcohol metabolic process", "d": ["The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019652", "l": "lactate fermentation to propionate and acetate", "d": ["The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035962", "l": "response to interleukin-13", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034340", "l": "response to type I interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098907", "l": "regulation of SA node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140609", "l": "phycocyanobilin biosynthetic process", "d": ["The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014049", "l": "positive regulation of glutamate secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042875", "l": "D-galactonate transmembrane transport", "d": ["The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903489", "l": "positive regulation of lactation", "d": ["Any process that activates or increases the frequency, rate or extent of lactation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015876", "l": "acetyl-CoA transport", "d": ["The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048669", "l": "collateral sprouting in absence of injury", "d": ["The process in which outgrowths develop from the axons of intact undamaged neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070802", "l": "regulation of metula development", "d": ["Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0051589", "l": "negative regulation of neurotransmitter transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0032413", "l": "negative regulation of ion transmembrane transporter activity", "d": ["Any process that stops or reduces the activity of an ion transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043587", "l": "tongue morphogenesis", "d": ["The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045122", "l": "aflatoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0030534", "l": "adult behavior", "d": ["Behavior in a fully developed and mature organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000053", "l": "regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035617", "l": "stress granule disassembly", "d": ["The disaggregation of a stress granule into its constituent protein and RNA parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904344", "l": "regulation of gastric mucosal blood circulation", "d": ["Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003393", "l": "neuron migration involved in retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0032291", "l": "axon ensheathment in central nervous system", "d": ["The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070199", "l": "establishment of protein localization to chromosome", "d": ["The directed movement of a protein to a specific location on a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070658", "l": "neuromast hair cell differentiation involved in neuromast regeneration", "d": ["Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006314", "l": "intron homing", "d": ["Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061373", "l": "mammillary axonal complex development", "d": ["The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006686", "l": "sphingomyelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0032371", "l": "regulation of sterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0016333", "l": "morphogenesis of follicular epithelium", "d": ["The process in which the anatomical structures of a follicular epithelium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0043268", "l": "positive regulation of potassium ion transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905183", "l": "negative regulation of protein serine/threonine phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060195", "l": "negative regulation of antisense RNA transcription", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016060", "l": "metarhodopsin inactivation", "d": ["The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901155", "l": "paromomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paromomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010759", "l": "positive regulation of macrophage chemotaxis", "d": ["Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002450", "l": "B cell antigen processing and presentation", "d": ["The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030649", "l": "aminoglycoside antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021786", "l": "branchiomotor neuron axon guidance in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014838", "l": "myoblast fate specification involved in skeletal muscle regeneration", "d": ["The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061890", "l": "positive regulation of astrocyte activation", "d": ["Any process that increases the frequency, rate or extent of astrocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032346", "l": "positive regulation of aldosterone metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031653", "l": "heat dissipation", "d": ["Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042365", "l": "water-soluble vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010183", "l": "pollen tube guidance", "d": ["The process in which the growth of pollen tube is directed towards the female gametophyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904087", "l": "negative regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901260", "l": "peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification", "d": ["Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032238", "l": "adenosine transport", "d": ["The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061870", "l": "positive regulation of hepatic stellate cell migration", "d": ["Any process that increases the frequency, rate or extent of hepatic stellate cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061026", "l": "cardiac muscle tissue regeneration", "d": ["The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.203304431560539", "identifiers": [{"i": "GO:0071396", "l": "cellular response to lipid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.24517279685756", "identifiers": [{"i": "GO:0008033", "l": "tRNA processing", "d": ["The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0048367", "l": "shoot system development", "d": ["The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000352", "l": "trans assembly of SL-containing precatalytic spliceosome", "d": ["Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.576528283568315", "identifiers": [{"i": "GO:0005975", "l": "carbohydrate metabolic process", "d": ["The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904426", "l": "positive regulation of GTP binding", "d": ["Any process that activates or increases the frequency, rate or extent of GTP binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901793", "l": "3-(3-hydroxyphenyl)propanoate metabolic process", "d": ["The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034307", "l": "regulation of ascospore formation", "d": ["Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902774", "l": "late endosome to lysosome transport", "d": ["The directed movement of substances from late endosome to lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001122", "l": "maltoheptaose metabolic process", "d": ["The chemical reactions and pathways involving a maltoheptaose."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061172", "l": "regulation of establishment of bipolar cell polarity", "d": ["Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905529", "l": "regulation of uracil import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of uracil import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048573", "l": "photoperiodism, flowering", "d": ["A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000753", "l": "positive regulation of glucosylceramide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000935", "l": "positive regulation of cellotriose metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048510", "l": "regulation of timing of transition from vegetative to reproductive phase", "d": ["The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009700", "l": "indole phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034694", "l": "response to prostaglandin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:2001088", "l": "trisaccharide transport", "d": ["The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006249", "l": "dCMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098506", "l": "polynucleotide 3' dephosphorylation", "d": ["The process of removing one or more phosphate groups from the 3' end of a polynucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061275", "l": "mesonephric proximal tubule development", "d": ["The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035311", "l": "wing cell fate specification", "d": ["The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035334", "l": "Notch receptor processing, ligand-independent", "d": ["The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032203", "l": "telomere formation via telomerase", "d": ["A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031525", "l": "menthol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048935", "l": "peripheral nervous system neuron development", "d": ["The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904153", "l": "negative regulation of retrograde protein transport, ER to cytosol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0042724", "l": "thiamine-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070340", "l": "detection of bacterial lipopeptide", "d": ["The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046442", "l": "aerobactin metabolic process", "d": ["The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901454", "l": "regulation of response to toluene", "d": ["Any process that modulates the frequency, rate or extent of response to toluene."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0000002", "l": "mitochondrial genome maintenance", "d": ["The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.904083843162937", "identifiers": [{"i": "GO:0021700", "l": "developmental maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072091", "l": "regulation of stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010189", "l": "vitamin E biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904818", "l": "visceral peritoneum development", "d": ["The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0070542", "l": "response to fatty acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904449", "l": "negative regulation of aspartate secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071983", "l": "exit from reproductive diapause", "d": ["The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070959", "l": "negative regulation of neutrophil mediated killing of fungus", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050977", "l": "magnetoreception by sensory perception of chemical stimulus", "d": ["The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904654", "l": "negative regulation of lung alveolus development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905418", "l": "positive regulation of amoeboid sperm motility", "d": ["Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019330", "l": "aldoxime metabolic process", "d": ["The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006744", "l": "ubiquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046772", "l": "viral budding from outer nuclear membrane", "d": ["The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0050918", "l": "positive chemotaxis", "d": ["The directed movement of a motile cell or organism towards a higher concentration of a chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0035835", "l": "indole alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900166", "l": "regulation of glial cell-derived neurotrophic factor production", "d": ["Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000622", "l": "regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043164", "l": "Gram-negative-bacterium-type cell wall biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000974", "l": "negative regulation of pro-B cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035900", "l": "response to isolation stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140050", "l": "negative regulation of endocardial cushion to mesenchymal transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010980", "l": "positive regulation of vitamin D 24-hydroxylase activity", "d": ["Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099149", "l": "regulation of postsynaptic neurotransmitter receptor internalization", "d": ["Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003384", "l": "apical constriction involved in gastrulation", "d": ["The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060857", "l": "establishment of glial blood-brain barrier", "d": ["Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:2001259", "l": "positive regulation of cation channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0042386", "l": "hemocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901741", "l": "positive regulation of myoblast fusion", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018922", "l": "iprodione metabolic process", "d": ["The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903356", "l": "positive regulation of distal tip cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of distal tip cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006671", "l": "phytosphingosine metabolic process", "d": ["The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150093", "l": "amyloid-beta clearance by transcytosis", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043950", "l": "positive regulation of cAMP-mediated signaling", "d": ["Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061446", "l": "endocardial cushion cell fate determination", "d": ["The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019689", "l": "pyrimidine nucleoside interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031029", "l": "regulation of septation initiation signaling", "d": ["Any process that modulates the frequency, rate or extent of septation initiation signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0035315", "l": "hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015970", "l": "guanosine tetraphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900196", "l": "regulation of penicillin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of penicillin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000617", "l": "positive regulation of histone H3-K9 acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050934", "l": "late stripe melanocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905861", "l": "intranuclear rod assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903762", "l": "positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0086045", "l": "membrane depolarization during AV node cell action potential", "d": ["The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002053", "l": "positive regulation of mesenchymal cell proliferation", "d": ["The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0099084", "l": "postsynaptic specialization organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903683", "l": "positive regulation of epithelial cell-cell adhesion involved in epithelium migration", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902003", "l": "regulation of amyloid-beta formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid-beta formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904615", "l": "cellular response to biphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090077", "l": "foam cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034286", "l": "response to maltose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080175", "l": "phragmoplast microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003308", "l": "negative regulation of Wnt signaling pathway involved in heart development", "d": ["Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010142", "l": "farnesyl diphosphate biosynthetic process, mevalonate pathway", "d": ["The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045056", "l": "transcytosis", "d": ["The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070471", "l": "uterine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900789", "l": "pseurotin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pseurotin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007043", "l": "cell-cell junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a junction between cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903296", "l": "positive regulation of glutamate secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010918", "l": "positive regulation of mitochondrial membrane potential", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0050687", "l": "negative regulation of defense response to virus", "d": ["Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990791", "l": "dorsal root ganglion development", "d": ["The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072702", "l": "response to methyl methanesulfonate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.518338488785304", "identifiers": [{"i": "GO:0046907", "l": "intracellular transport", "d": ["The directed movement of substances within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902659", "l": "regulation of glucose mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044313", "l": "protein K6-linked deubiquitination", "d": ["A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0032369", "l": "negative regulation of lipid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043180", "l": "rhythmic inhibition", "d": ["Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901263", "l": "positive regulation of sorocarp spore cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051923", "l": "sulfation", "d": ["The addition of a sulfate group to a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006824", "l": "cobalt ion transport", "d": ["The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903340", "l": "positive regulation of cell wall organization or biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010223", "l": "secondary shoot formation", "d": ["The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009413", "l": "response to flooding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021618", "l": "hypoglossal nerve morphogenesis", "d": ["The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000351", "l": "regulation of endothelial cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0035916", "l": "modulation of calcium channel activity in another organism", "d": ["Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003273", "l": "cell migration involved in endocardial cushion formation", "d": ["The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903814", "l": "regulation of collecting lymphatic vessel constriction", "d": ["Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905803", "l": "negative regulation of cellular response to manganese ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905406", "l": "positive regulation of mitotic cohesin loading", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061623", "l": "glycolytic process from galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060870", "l": "cell wall disassembly involved in floral organ abscission", "d": ["A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0043299", "l": "leukocyte degranulation", "d": ["The regulated exocytosis of secretory granules by a leukocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006474", "l": "N-terminal protein amino acid acetylation", "d": ["The acetylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0008356", "l": "asymmetric cell division", "d": ["The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902898", "l": "fatty acid methyl ester metabolic process", "d": ["The chemical reactions and pathways involving fatty acid methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901220", "l": "negative regulation of cardiac chamber morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006386", "l": "termination of RNA polymerase III transcription", "d": ["A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042811", "l": "pheromone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0032890", "l": "regulation of organic acid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006084", "l": "acetyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006761", "l": "dihydrofolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0086005", "l": "ventricular cardiac muscle cell action potential", "d": ["An action potential that occurs in a ventricular cardiac muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901599", "l": "(-)-pinoresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-pinoresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0015723", "l": "bilirubin transport", "d": ["The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.368095522595297", "identifiers": [{"i": "GO:0071897", "l": "DNA biosynthetic process", "d": ["The biosynthetic process resulting in the formation of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043102", "l": "amino acid salvage", "d": ["Any process which produces an amino acid from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900036", "l": "positive regulation of cellular response to heat", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110005", "l": "positive regulation of tRNA C5-cytosine methylation", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034145", "l": "positive regulation of toll-like receptor 4 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.788731709144329", "identifiers": [{"i": "GO:0044355", "l": "clearance of foreign intracellular DNA", "d": ["A defense process that protects an organism from invading foreign DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901614", "l": "positive regulation of terminal button organization", "d": ["Any process that activates or increases the frequency, rate or extent of terminal button organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.808184427458961", "identifiers": [{"i": "GO:0043413", "l": "macromolecule glycosylation", "d": ["The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097279", "l": "histamine secretion mediated by IgE immunoglobulin", "d": ["Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0086092", "l": "regulation of the force of heart contraction by cardiac conduction", "d": ["A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120291", "l": "negative regulation of mitotic recombination-dependent replication fork processing", "d": ["Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. 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The digestive tract is the anatomical structure through which food passes and is processed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002651", "l": "positive regulation of tolerance induction to self antigen", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009603", "l": "detection of symbiotic fungus", "d": ["The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051897", "l": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904435", "l": "regulation of transferrin receptor binding", "d": ["Any process that modulates the frequency, rate or extent of transferrin receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903526", "l": "negative regulation of membrane tubulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042198", "l": "nylon metabolic process", "d": ["The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904389", "l": "rod bipolar cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.345324670587374", "identifiers": [{"i": "GO:0009891", "l": "positive regulation of biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901673", "l": "regulation of mitotic spindle assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic spindle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031590", "l": "wybutosine metabolic process", "d": ["The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039709", "l": "cytoplasmic capsid assembly", "d": ["The assembly of a virus capsid that occurs in the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030909", "l": "non-intein-mediated protein splicing", "d": ["The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000396", "l": "negative regulation of ubiquitin-dependent endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090229", "l": "negative regulation of red or far-red light signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035712", "l": "T-helper 2 cell activation", "d": ["The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061255", "l": "mesonephric glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901296", "l": "negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035075", "l": "response to ecdysone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0070664", "l": "negative regulation of leukocyte proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990258", "l": "histone glutamine methylation", "d": ["The modification of a histone by addition of a methyl group to an glutamine residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035702", "l": "monocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032745", "l": "positive regulation of interleukin-21 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-21 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0007350", "l": "blastoderm segmentation", "d": ["The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015687", "l": "ferric-hydroxamate import into cell", "d": ["A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097317", "l": "invasive growth in response to biotic stimulus", "d": ["The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035009", "l": "negative regulation of melanization defense response", "d": ["Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902227", "l": "negative regulation of macrophage colony-stimulating factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072385", "l": "minus-end-directed organelle transport along microtubule", "d": ["The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039703", "l": "RNA replication", "d": ["The cellular metabolic process in which a cell duplicates one or more molecules of RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901182", "l": "regulation of camalexin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of camalexin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030393", "l": "fructoselysine metabolic process", "d": ["The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902833", "l": "positive regulation of cell proliferation in dorsal spinal cord", "d": ["Any process that activates or increases the frequency, rate or extent of cell 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"d": ["Any viral process that interferes with the processing of mRNA in the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045208", "l": "MAPK phosphatase export from nucleus", "d": ["The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000946", "l": "negative regulation of amylopectin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.592817335335198", "identifiers": [{"i": "GO:0009593", "l": "detection of chemical stimulus", "d": ["The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042463", "l": "ocellus photoreceptor cell development", "d": ["Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904653", "l": "regulation of lung alveolus development", "d": ["Any process that modulates the frequency, rate or extent of lung alveolus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046627", "l": "negative regulation of insulin receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052129", "l": "negative energy taxis", "d": ["The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030035", "l": "microspike assembly", "d": ["Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000032", "l": "cell wall mannoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901032", "l": "negative regulation of response to reactive oxygen species", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.634102831637321", "identifiers": [{"i": "GO:0034097", "l": "response to cytokine", "d": ["Any process that 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"d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007453", "l": "clypeo-labral disc morphogenesis", "d": ["The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010226", "l": "response to lithium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045985", "l": "positive regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0021550", "l": "medulla oblongata development", "d": ["The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060314", "l": "regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0008653", "l": "lipopolysaccharide metabolic process", "d": ["The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051141", "l": "negative regulation of NK T cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097345", "l": "mitochondrial outer membrane permeabilization", "d": ["The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106077", "l": "histone succinylation", "d": ["The modification of a histone by the addition of an succinyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045040", "l": "protein insertion into mitochondrial outer membrane", "d": ["The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.85341545293393", "identifiers": [{"i": "GO:0007611", "l": "learning or memory", "d": ["The acquisition and processing of information and/or the storage and retrieval of this information over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046096", "l": "deoxyuridine metabolic process", "d": ["The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072126", "l": "positive regulation of glomerular mesangial cell proliferation", "d": ["Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021612", "l": "facial nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018916", "l": "nitrobenzene metabolic process", "d": ["The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900951", "l": "negative regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.519451917212066", "identifiers": [{"i": "GO:0051607", "l": "defense response to virus", "d": ["Reactions triggered in response to the presence of a virus that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019744", "l": "hopanoid metabolic process", "d": ["The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0007476", "l": "imaginal disc-derived wing morphogenesis", "d": ["The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075017", "l": "regulation of appressorium formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont appressorium formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0090311", "l": "regulation of protein deacetylation", "d": ["Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032987", "l": "protein-lipid complex disassembly", "d": ["The disaggregation of a protein-lipid complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.291117080290377", "identifiers": [{"i": "GO:0007585", "l": "respiratory gaseous exchange by respiratory system", "d": ["The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061105", "l": "regulation of stomach neuroendocrine cell differentiation", "d": ["Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046347", "l": "mannosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106296", "l": "D-series resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001556", "l": "oocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044495", "l": "modulation of blood pressure in another organism", "d": ["A process by which one organism modulates the force with which blood travels through the circulatory system of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035169", "l": "lymph gland plasmatocyte differentiation", "d": ["The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002523", "l": "leukocyte migration involved in inflammatory response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060708", "l": "spongiotrophoblast differentiation", "d": ["The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140861", "l": "DNA repair-dependent chromatin remodeling", "d": ["A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035493", "l": "SNARE complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070142", "l": "synaptic vesicle budding", "d": ["Evagination of a membrane to form a synaptic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051202", "l": "phytochromobilin metabolic process", "d": ["The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0018342", "l": "protein prenylation", "d": ["The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044790", "l": "suppression of viral release by host", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.84994440557243", "identifiers": [{"i": "GO:0050953", "l": "sensory perception of light stimulus", "d": ["The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900288", "l": "regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process", "d": ["Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090133", "l": "mesendoderm migration", "d": ["The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010832", "l": "negative regulation of myotube differentiation", "d": ["Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009136", "l": "purine nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010903", "l": "negative regulation of very-low-density lipoprotein particle remodeling", "d": ["Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.032325769543199", "identifiers": [{"i": "GO:0044848", "l": "biological phase", "d": ["A distinct period or stage in a biological process or cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044520", "l": "envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904329", "l": "negative regulation of myofibroblast contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006554", "l": "lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160059", "l": "programmed cell death in response to retinoic acid", "d": ["Cell death resulting from activation of endogenous cellular processes and occurring as a result of a retinoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903281", "l": "positive regulation of calcium:sodium antiporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0061440", "l": "kidney vasculature development", "d": ["The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.400129184613753", "identifiers": [{"i": "GO:0150063", "l": "visual system development", "d": ["The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010482", "l": "regulation of epidermal cell division", "d": ["Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000395", "l": "regulation of ubiquitin-dependent endocytosis", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0048103", "l": "somatic stem cell division", "d": ["The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0018210", "l": "peptidyl-threonine modification", "d": ["The modification of peptidyl-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905632", "l": "protein localization to euchromatin", "d": ["A process in which a protein is transported to, or maintained in, a location within an euchromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071838", "l": "cell proliferation in bone marrow", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903339", "l": "negative regulation of cell wall organization or biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110013", "l": "positive regulation of aggregation involved in sorocarp development", "d": ["Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0044501", "l": "perturbation of signal transduction in another organism", "d": ["The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904866", "l": "ventral tegmental area development", "d": ["The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0016114", "l": "terpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071292", "l": "cellular response to silver ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072184", "l": "renal vesicle progenitor cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0055006", "l": "cardiac cell development", "d": ["The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.833128032771839", "identifiers": [{"i": "GO:0002833", "l": "positive regulation of response to biotic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033084", "l": "regulation of immature T cell proliferation in thymus", "d": ["Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903527", "l": "positive regulation of membrane tubulation", "d": ["Any process that activates or increases the frequency, rate or extent of membrane tubulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003194", "l": "sinoatrial valve formation", "d": ["The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080157", "l": "regulation of plant-type cell wall organization or biogenesis", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0014820", "l": "tonic smooth muscle contraction", "d": ["A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071298", "l": "cellular response to L-ascorbic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901499", "l": "response to hexane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010456", "l": "cell proliferation in dorsal spinal cord", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900232", "l": "negative regulation of single-species biofilm formation on inanimate substrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032640", "l": "tumor necrosis factor production", "d": ["The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901174", "l": "phytoene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytoene."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010248", "l": "establishment or maintenance of transmembrane electrochemical gradient", "d": ["The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0070942", "l": "neutrophil mediated cytotoxicity", "d": ["The directed killing of a target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061274", "l": "mesonephric distal tubule development", "d": ["The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160048", "l": "craniofacial suture closure", "d": ["The process of fusing together the edges of a craniofacial suture."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140540", "l": "negative regulation melanotic encapsulation of foreign target", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014716", "l": "skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration", "d": ["Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0007618", "l": "mating", "d": ["The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002419", "l": "T cell mediated cytotoxicity directed against tumor cell target", "d": ["The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046881", "l": "positive regulation of follicle-stimulating hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006337", "l": "nucleosome disassembly", "d": ["The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901822", "l": "delta-carotene metabolic process", "d": ["The chemical reactions and pathways involving delta-carotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009877", "l": "nodulation", "d": ["The formation of nitrogen-fixing root nodules on plant roots."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140462", "l": "pericentric heterochromatin organization", "d": ["The organization of chromatin into heterochromatin at the pericentric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071391", "l": "cellular response to estrogen stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042539", "l": "hypotonic salinity response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071868", "l": "cellular response to monoamine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0040019", "l": "positive regulation of embryonic development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905339", "l": "positive regulation of cohesin unloading", "d": ["Any process that activates or increases the frequency, rate or extent of cohesin unloading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140502", "l": "effector-mediated suppression of host salicylic acid-mediated innate immune signaling", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903225", "l": "negative regulation of endodermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019742", "l": "pentacyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050945", "l": "positive regulation of iridophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of iridophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033137", "l": "negative regulation of peptidyl-serine phosphorylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010672", "l": "regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051133", "l": "regulation of NK T cell activation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904143", "l": "positive regulation of carotenoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010414", "l": "glucuronoarabinoxylan metabolic process", "d": ["The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007147", "l": "female meiosis II", "d": ["The cell cycle process in which the second meiotic division occurs in the female germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903370", "l": "positive regulation of foraging behavior", "d": ["Any process that activates or increases the frequency, rate or extent of foraging behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0016577", "l": "histone demethylation", "d": ["The modification of histones by removal of methyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051365", "l": "cellular response to potassium ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902933", "l": "isopentenol metabolic process", "d": ["The chemical reactions and pathways involving isopentenol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039573", "l": "suppression by virus of host complement activation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010900", "l": "negative regulation of phosphatidylcholine catabolic process", "d": ["Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070778", "l": "L-aspartate transmembrane transport", "d": ["The directed movement of L-aspartate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0099543", "l": "trans-synaptic signaling by soluble gas", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032958", "l": "inositol phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:1901976", "l": "regulation of cell cycle checkpoint", "d": ["Any process that modulates the frequency, rate or extent of cell cycle checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021576", "l": "hindbrain formation", "d": ["The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006573", "l": "valine metabolic process", "d": ["The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.083535053380338", "identifiers": [{"i": "GO:0019438", "l": "aromatic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060013", "l": "righting reflex", "d": ["A reflex process in which an animal immediately tries to turn over after being placed in a supine position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018060", "l": "N-terminal peptidyl-cysteine deamination", "d": ["The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0030397", "l": "membrane disassembly", "d": ["The controlled breakdown of any cell membrane in the context of a normal process such as autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0035738", "l": "envenomation resulting in modulation of process in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903591", "l": "negative regulation of lysozyme activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032383", "l": "regulation of intracellular cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061033", "l": "secretion by lung epithelial cell involved in lung growth", "d": ["The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070657", "l": "neuromast regeneration", "d": ["The regrowth of a neuromast following its loss or destruction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039707", "l": "pore formation by virus in membrane of host cell", "d": ["The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0060420", "l": "regulation of heart growth", "d": ["Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009291", "l": "unidirectional conjugation", "d": ["The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells. Some or all of the chromosome(s) of the donor cell is transferred into the recipient cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060486", "l": "club cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034160", "l": "negative regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010875", "l": "positive regulation of cholesterol efflux", "d": ["Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006404", "l": "RNA import into nucleus", "d": ["The import of RNA from the cytoplasm to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034110", "l": "regulation of homotypic cell-cell adhesion", "d": ["Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003275", "l": "apoptotic process involved in outflow tract morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900249", "l": "positive regulation of cytoplasmic translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003214", "l": "cardiac left ventricle morphogenesis", "d": ["The process in which the left cardiac ventricle is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0015975", "l": "energy derivation by oxidation of reduced inorganic compounds", "d": ["The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014816", "l": "skeletal muscle satellite cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a satellite cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0044820", "l": "mitotic telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003316", "l": "establishment of myocardial progenitor cell apical/basal polarity", "d": ["The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000274", "l": "regulation of epithelial cell migration, open tracheal system", "d": ["Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002848", "l": "positive regulation of T cell tolerance induction to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033584", "l": "tyrosine biosynthetic process from chorismate via L-arogenate", "d": ["The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0019740", "l": "nitrogen utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903058", "l": "positive regulation of melanosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of melanosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010709", "l": "heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing", "d": ["The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904644", "l": "cellular response to curcumin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042200", "l": "cyanuric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1900910", "l": "positive regulation of olefin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of olefin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032424", "l": "negative regulation of mismatch repair", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015903", "l": "fluconazole transport", "d": ["The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075325", "l": "spore dispersal", "d": ["Any process in which an organism disseminates its spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0007630", "l": "jump response", "d": ["The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904059", "l": "regulation of locomotor rhythm", "d": ["Any process that modulates the frequency, rate or extent of locomotor rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901868", "l": "ecgonine methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.454737133015534", "identifiers": [{"i": "GO:0002456", "l": "T cell mediated immunity", "d": ["Any process involved in the carrying out of an immune response by a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:1903317", "l": "regulation of protein maturation", "d": ["Any process that modulates the frequency, rate or extent of protein maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1902047", "l": "polyamine transmembrane transport", "d": ["The process in which a polyamine macromolecule is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075323", "l": "positive regulation of oomycete sporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071955", "l": "recycling endosome to Golgi transport", "d": ["The directed movement of substances from recycling endosomes to the Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015867", "l": "ATP transport", "d": ["The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009144", "l": "purine nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140886", "l": "suppression by virus of host interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090618", "l": "DNA clamp unloading", "d": ["The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0018158", "l": "protein oxidation", "d": ["The modification of a protein amino acid by oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050944", "l": "negative regulation of xanthophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044814", "l": "glycolytic fermentation via PFL pathway", "d": ["The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0030317", "l": "flagellated sperm motility", "d": ["The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903078", "l": "positive regulation of protein localization to plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031173", "l": "otolith mineralization completed early in development", "d": ["The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046664", "l": "dorsal closure, amnioserosa morphology change", "d": ["The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0180010", "l": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "d": ["Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional mRNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000176", "l": "positive regulation of pro-T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044073", "l": "modulation by symbiont of host translation", "d": ["The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019569", "l": "L-arabinose catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035397", "l": "helper T cell enhancement of adaptive immune response", "d": ["Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060745", "l": "mammary gland branching involved in pregnancy", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061147", "l": "endocardial endothelium development", "d": ["The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042419", "l": "epinephrine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903728", "l": "luteal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901193", "l": "regulation of formation of translation preinitiation complex", "d": ["Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018361", "l": "peptidyl-glutamine 2-methylation", "d": ["The methylation of glutamine to form 2-methyl-L-glutamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003296", "l": "apoptotic process involved in atrial ventricular junction remodeling", "d": ["Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009264", "l": "deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001009", "l": "regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0007634", "l": "optokinetic behavior", "d": ["The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900839", "l": "positive regulation of fumigaclavine C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072227", "l": "metanephric macula densa development", "d": ["The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002557", "l": "histamine secretion by basophil", "d": ["The regulated release of histamine by a basophil or group of basophils."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902708", "l": "response to plumbagin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021529", "l": "spinal cord oligodendrocyte cell differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0072683", "l": "T cell extravasation", "d": ["The migration of a T cell from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010023", "l": "proanthocyanidin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of proanthocyanidin."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006074", "l": "(1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000073", "l": "initial mitotic spindle pole body separation", "d": ["The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900709", "l": "positive regulation of tensidol A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072704", "l": "response to mercaptoethanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0061900", "l": "glial cell activation", "d": ["A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061100", "l": "lung neuroendocrine cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0050764", "l": "regulation of phagocytosis", "d": ["Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061152", "l": "trachea submucosa development", "d": ["The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110141", "l": "L-glutamate import into mitochondrion", "d": ["The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0052318", "l": "regulation of phytoalexin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160061", "l": "respiratory chemosensitivity", "d": ["A homeostatic process by which the sensing of CO2 and/or H+ by the brain leads to appropriate altering in breathing to regulate blood gas and tissue pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902317", "l": "nuclear DNA replication termination", "d": ["Any DNA replication termination that is involved in nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044076", "l": "positive regulation by symbiont of host vacuole organization", "d": ["The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042868", "l": "antisense RNA metabolic process", "d": ["The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905029", "l": "positive regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090029", "l": "negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "d": ["Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990497", "l": "regulation of cytoplasmic translation in response to stress", "d": ["Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021523", "l": "somatic motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061873", "l": "regulation of hepatic stellate cell contraction", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900357", "l": "regulation of nigerotriose transport", "d": ["Any process that modulates the frequency, rate or extent of nigerotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051624", "l": "inhibition of norepinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of norepinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032307", "l": "negative regulation of prostaglandin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900469", "l": "negative regulation of phosphatidylserine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033072", "l": "vancomycin biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070130", "l": "negative regulation of mitochondrial translation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032916", "l": "positive regulation of transforming growth factor beta3 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060317", "l": "cardiac epithelial to mesenchymal transition", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046151", "l": "eye pigment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905612", "l": "positive regulation of mRNA cap binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA cap binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007270", "l": "neuron-neuron synaptic transmission", "d": ["The process of synaptic transmission from a neuron to another neuron across a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015811", "l": "L-cystine transport", "d": ["The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060878", "l": "pouch outgrowth involved in semicircular canal formation", "d": ["The morphogenetic process in which an epithelial sheet bends along 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A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048893", "l": "afferent axon development in lateral line nerve", "d": ["The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2001135", "l": "regulation of endocytic recycling", "d": ["Any process that modulates the frequency, rate or extent of endocytic recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060233", "l": "oenocyte delamination", "d": ["The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0075310", "l": "regulation of sporangium development", "d": ["Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903085", "l": "regulation of sinapate ester biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007077", "l": "mitotic nuclear membrane disassembly", "d": ["The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000329", "l": "negative regulation of T-helper 17 cell lineage commitment", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904703", "l": "negative regulation of protein localization to adherens junction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902169", "l": "cellular response to catechin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903607", "l": "cytochrome c biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytochrome c."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.225967377332346", "identifiers": [{"i": "GO:0098609", "l": "cell-cell adhesion", "d": ["The attachment of one cell to another cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045542", "l": "positive regulation of cholesterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.180458012661006", "identifiers": [{"i": "GO:1901617", "l": "organic hydroxy compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organic hydroxy compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0036115", "l": "fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1902102", "l": "regulation of metaphase/anaphase 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It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0036260", "l": "RNA capping", "d": ["The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021746", "l": "solitary nucleus development", "d": ["The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015847", "l": "putrescine transport", "d": ["The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0030186", "l": "melatonin metabolic process", "d": ["The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009219", "l": "pyrimidine deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905079", "l": "regulation of cerebellar neuron development", "d": ["Any process that modulates the frequency, rate or extent of cerebellar neuron development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010477", "l": "response to sulfur dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061075", "l": "positive regulation of neural retina development", "d": ["Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090074", "l": "negative regulation of protein homodimerization activity", "d": ["Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901779", "l": "pentalenolactone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentalenolactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:1904019", "l": "epithelial cell apoptotic process", "d": ["Any apoptotic process in an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044601", "l": "protein denucleotidylation", "d": ["The removal of a nucleotide from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0014010", "l": "Schwann cell proliferation", "d": ["The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061281", "l": "specification of mesonephric connecting tubule identity", "d": ["The process in which the connecting tubule of the mesonephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046677", "l": "response to antibiotic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090184", "l": "positive regulation of kidney development", "d": ["Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.80017642001669", "identifiers": [{"i": "GO:0007599", "l": "hemostasis", "d": ["The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900346", "l": "negative regulation of methane biosynthetic process from methanethiol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0008654", "l": "phospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0008272", "l": "sulfate transport", "d": ["The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905080", "l": "negative regulation of cerebellar neuron development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036116", "l": "long-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039501", "l": "suppression by virus of host type I interferon production", "d": ["Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006535", "l": "cysteine biosynthetic process from serine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060929", "l": "atrioventricular node cell fate commitment", "d": ["The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043553", "l": "negative regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0034329", "l": "cell junction assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990481", "l": "mRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an mRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042496", "l": "detection of diacyl bacterial lipopeptide", "d": ["The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045232", "l": "S-layer organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903974", "l": "positive regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045820", "l": "negative regulation of glycolytic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903188", "l": "positive regulation of vitellogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of vitellogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901112", "l": "actinorhodin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of actinorhodin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018899", "l": "1,2-dichloroethane metabolic process", "d": ["The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003385", "l": "cell-cell signaling involved in amphid sensory organ development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900581", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000541", "l": "positive regulation of protein geranylgeranylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046898", "l": "response to cycloheximide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048704", "l": "embryonic skeletal system morphogenesis", "d": ["The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060493", "l": "mesenchymal-endodermal cell signaling involved in lung induction", "d": ["Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072226", "l": "metanephric long descending thin limb bend development", "d": ["The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1902296", "l": "DNA strand elongation involved in cell cycle DNA replication", "d": ["Any DNA strand elongation that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070617", "l": "negative regulation of thiamine diphosphate biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075264", "l": "regulation of oogonium development", "d": ["Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060281", "l": "regulation of oocyte development", "d": ["Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000385", "l": "positive regulation of ectoderm development", "d": ["Any process that activates or increases the frequency, rate or extent of ectoderm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0052029", "l": "symbiont-mediated suppression of host signal transduction pathway", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a host signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042074", "l": "cell migration involved in gastrulation", "d": ["The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903855", "l": "positive regulation of stress response to copper ion", "d": ["Any process that activates or increases the frequency, rate or extent of stress response to copper ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0015774", "l": "polysaccharide transport", "d": ["The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010964", "l": "regulation of regulatory ncRNA-mediated heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.592359821609847", "identifiers": [{"i": "GO:0030183", "l": "B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010896", "l": "regulation of triglyceride catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060551", "l": "regulation of fructose 1,6-bisphosphate metabolic process", "d": ["Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106383", "l": "dAMP salvage", "d": ["Any process which produces a dAMP from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901384", "l": "positive regulation of chorionic trophoblast cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061530", "l": "aspartate secretion, neurotransmission", "d": ["The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902065", "l": "response to L-glutamate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052575", "l": "carbohydrate localization", "d": ["Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:1901888", "l": "regulation of cell junction assembly", "d": ["Any process that modulates the frequency, rate or extent of cell junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006431", "l": "methionyl-tRNA aminoacylation", "d": ["The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031619", "l": "homologous chromosome orientation in meiotic metaphase I", "d": ["The cell cycle process in which the sister centromeres and kinetochores of one chromosome are fused and orientated so the chromosomes attach to microtubules that emanate from the same spindle pole. This process ensures that homologous l chromosomes are segregated at anaphase of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033135", "l": "regulation of peptidyl-serine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097474", "l": "retinal cone cell apoptotic process", "d": ["Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900226", "l": "negative regulation of NLRP3 inflammasome complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0050730", "l": "regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000601", "l": "positive regulation of Arp2/3 complex-mediated actin nucleation", "d": ["Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046100", "l": "hypoxanthine metabolic process", "d": ["The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905259", "l": "negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904328", "l": "regulation of myofibroblast contraction", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044656", "l": "regulation of post-lysosomal vacuole size", "d": ["Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010590", "l": "regulation of septum digestion after cytokinesis", "d": ["Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901887", "l": "2-hydroxybenzoyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900351", "l": "regulation of methanofuran biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1990822", "l": "basic amino acid transmembrane transport", "d": ["The directed movement of basic amino acids from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046150", "l": "melanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097500", "l": "receptor localization to non-motile cilium", "d": ["A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090720", "l": "primary adaptive immune response", "d": ["An adaptive immune response against an antigen not previously encountered by immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0023058", "l": "adaptation of signaling pathway", "d": ["The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010828", "l": "positive regulation of glucose transmembrane transport", "d": ["Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044643", "l": "envenomation resulting in positive regulation of complement activation, alternative pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051693", "l": "actin filament capping", "d": ["The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018978", "l": "anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process", "d": ["The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1903467", "l": "negative regulation of mitotic DNA replication initiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904861", "l": "excitatory synapse assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.379440784744453", "identifiers": [{"i": "GO:2000026", "l": "regulation of multicellular organismal development", "d": ["Any process that modulates the frequency, rate or extent of multicellular organismal development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905588", "l": "plant-type cell wall modification involved in stomatal movement", "d": ["Any plant-type cell wall modification that is involved in stomatal movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010749", "l": "regulation of nitric oxide mediated signal transduction", "d": ["Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.75272396535307", "identifiers": [{"i": "GO:0006699", "l": "bile acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019921", "l": "peptidyl-1-thioglycine biosynthetic process, carboxy-terminal", "d": ["The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0050672", "l": "negative regulation of lymphocyte proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060749", "l": "mammary gland alveolus development", "d": ["The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042673", "l": "regulation of retinal cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a retinal cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044867", "l": "modulation by host of viral catalytic activity", "d": ["The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002714", "l": "positive regulation of B cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031114", "l": "regulation of microtubule depolymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042928", "l": "ferrichrome import into cell", "d": ["A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901152", "l": "vistamycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vistamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090385", "l": "phagosome-lysosome fusion", "d": ["The creation of a phagolysosome from a phagosome and a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900227", "l": "positive regulation of NLRP3 inflammasome complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061169", "l": "positive regulation of hair placode formation", "d": ["Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033108", "l": "mitochondrial respiratory chain complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000186", "l": "negative regulation of phosphate transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000748", "l": "conjugation with mutual genetic exchange", "d": ["A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0036214", "l": "contractile ring localization", "d": ["The process in which a contractile ring is positioned or maintained in a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905072", "l": "cardiac jelly development", "d": ["The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006420", "l": "arginyl-tRNA aminoacylation", "d": ["The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097490", "l": "sympathetic neuron projection extension", "d": ["Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098885", "l": "modification of postsynaptic actin cytoskeleton", "d": ["Any process that modifies the structure of a postsynaptic actin cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061646", "l": "positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0043949", "l": "regulation of cAMP-mediated signaling", "d": ["Any process which modulates the frequency, rate or extent of cAMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0061756", "l": "leukocyte adhesion to vascular endothelial cell", "d": ["The attachment of a leukocyte to vascular endothelial cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0015793", "l": "glycerol transmembrane transport", "d": ["The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060318", "l": "definitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002269", "l": "leukocyte activation involved in inflammatory response", "d": ["A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904676", "l": "negative regulation of somatic stem cell division", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.425307508868073", "identifiers": [{"i": "GO:0031325", "l": "positive regulation of cellular metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080149", "l": "sucrose induced translational repression", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903142", "l": "positive regulation of establishment of endothelial barrier", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071231", "l": "cellular response to folic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035112", "l": "genitalia morphogenesis", "d": ["The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006653", "l": "1,2-diacyl-sn-glycero-3-phosphocholine metabolic process", "d": ["The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044503", "l": "modulation of G protein-coupled receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902736", "l": "positive regulation of receptor-mediated virion attachment to host cell", "d": ["Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0001821", "l": "histamine secretion", "d": ["The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902821", "l": "1-undecene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-undecene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048904", "l": "anterior lateral line neuromast cupula development", "d": ["The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075291", "l": "positive regulation of aplanospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030960", "l": "peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine", "d": ["The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030994", "l": "primary cell septum disassembly", "d": ["Dissolution of the primary septum during cell separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045188", "l": "regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0007286", "l": "spermatid development", "d": ["The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0098927", "l": "vesicle-mediated transport between endosomal compartments", "d": ["A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035219", "l": "prothoracic disc development", "d": ["Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019228", "l": "neuronal action potential", "d": ["An action potential that occurs in a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003365", "l": "establishment of cell polarity involved in ameboidal cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030953", "l": "astral microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009189", "l": "deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1905359", "l": "protein localization to meiotic spindle", "d": ["A process in which a protein is transported to, or maintained in, a location within a meiotic spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900891", "l": "negative regulation of pentadecane metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071708", "l": "immunoglobulin light chain V-J recombination", "d": ["The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072075", "l": "metanephric mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905906", "l": "regulation of amyloid fibril formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid fibril formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002138", "l": "retinoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903546", "l": "protein localization to photoreceptor outer segment", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070494", "l": "regulation of thrombin-activated receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031622", "l": "positive regulation of fever generation", "d": ["Any process that activates or increases the frequency, rate, or extent of fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.590866249919607", "identifiers": [{"i": "GO:0001775", "l": "cell activation", "d": ["A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007137", "l": "meiotic metaphase II", "d": ["The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006068", "l": "ethanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.769355763942954", "identifiers": [{"i": "GO:0050673", "l": "epithelial cell proliferation", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033586", "l": "L-phenylalanine biosynthetic process from chorismate via L-arogenate", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021802", "l": "somal translocation", "d": ["The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072432", "l": "response to G1 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0005988", "l": "lactose metabolic process", "d": ["The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019260", "l": "1,2-dichloroethane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043322", "l": "negative regulation of natural killer cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of natural killer cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0048562", "l": "embryonic organ morphogenesis", "d": ["Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.20186355550635", "identifiers": [{"i": "GO:0043171", "l": "peptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035263", "l": "genital disc sexually dimorphic development", "d": ["The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046124", "l": "purine deoxyribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019481", "l": "L-alanine catabolic process, by transamination", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0002778", "l": "antibacterial peptide production", "d": ["The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001140", "l": "positive regulation of phospholipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipid transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075271", "l": "zygosporangium development", "d": ["The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018151", "l": "peptide cross-linking via L-histidyl-L-tyrosine", "d": ["The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071452", "l": "cellular response to singlet oxygen", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009073", "l": "aromatic amino acid family biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904901", "l": "positive regulation of myosin II filament organization", "d": ["Any process that activates or increases the frequency, rate or extent of myosin II filament organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901210", "l": "regulation of cardiac chamber formation", "d": ["Any process that modulates the frequency, rate or extent of cardiac chamber formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021613", "l": "facial nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062087", "l": "positive regulation of vein smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vein smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010233", "l": "phloem transport", "d": ["The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045069", "l": "regulation of viral genome replication", "d": ["Any process that modulates the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043622", "l": "cortical microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044828", "l": "negative regulation by host of viral genome replication", "d": ["A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072725", "l": "cellular response to 4-nitroquinoline N-oxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904525", "l": "positive regulation of DNA amplification", "d": ["Any process that activates or increases the frequency, rate or extent of DNA amplification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048162", "l": "multi-layer follicle stage", "d": ["The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048508", "l": "embryonic meristem development", "d": ["The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0044154", "l": "histone H3-K14 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106110", "l": "vomitoxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009643", "l": "photosynthetic acclimation", "d": ["A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007073", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.773755611440492", "identifiers": [{"i": "GO:0044255", "l": "cellular lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060138", "l": "fetal process involved in parturition", "d": ["A reproductive process occurring in the embryo that results in birth."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.306098259633643", "identifiers": [{"i": "GO:0006821", "l": "chloride transport", "d": ["The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904574", "l": "negative regulation of selenocysteine insertion sequence binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045311", "l": "invasive growth in response to pheromone", "d": ["The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008617", "l": "guanosine metabolic process", "d": ["The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000990", "l": "positive regulation of hemicellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042122", "l": "alginic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072449", "l": "response to G1 cell size control checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021928", "l": "basket cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021757", "l": "caudate nucleus development", "d": ["The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071727", "l": "cellular response to triacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0080186", "l": "developmental vegetative growth", "d": ["The increase in size or mass of non-reproductive plant parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042683", "l": "negative regulation of compound eye cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060365", "l": "coronal suture morphogenesis", "d": ["The process in which the coronal suture is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002411", "l": "T cell tolerance induction to tumor cell", "d": ["A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021985", "l": "neurohypophysis development", "d": ["The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060189", "l": "positive regulation of protein desumoylation", "d": ["Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018230", "l": "peptidyl-L-cysteine S-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090428", "l": "perianth development", "d": ["The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902053", "l": "regulation of neosartoricin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0034090", "l": "maintenance of meiotic sister chromatid cohesion", "d": ["The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0036010", "l": "protein localization to endosome", "d": ["A process in which a protein is transported to, or maintained in, a location within an endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009960", "l": "endosperm development", "d": ["The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900691", "l": "positive regulation of gliotoxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032872", "l": "regulation of stress-activated MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060178", "l": "regulation of exocyst localization", "d": ["Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140922", "l": "positive regulation of thermomorphogenesis", "d": ["Any process that increases the rate, frequency or extent of thermomorphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:2000136", "l": "regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902005", "l": "regulation of proline biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of proline biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990708", "l": "conditioned place preference", "d": ["The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007561", "l": "imaginal disc eversion", "d": ["The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072139", "l": "glomerular parietal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060696", "l": "regulation of phospholipid catabolic process", "d": ["Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097353", "l": "centrolateral pattern formation", "d": ["The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901497", "l": "response to diphenyl ether", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990171", "l": "SCF complex disassembly in response to cadmium stress", "d": ["The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902198", "l": "3-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0039657", "l": "suppression by virus of host gene expression", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901878", "l": "positive regulation of calcium ion binding", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0062223", "l": "regulation of somatic muscle development", "d": ["Any process that regulates the rate, frequency or extent of somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045976", "l": "negative regulation of mitotic cell cycle, embryonic", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002847", "l": "negative regulation of T cell tolerance induction to tumor cell", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018004", "l": "N-terminal protein formylation", "d": ["The formylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032125", "l": "micronucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015819", "l": "lysine transport", "d": ["The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904439", "l": "negative regulation of iron ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905808", "l": "positive regulation of synapse pruning", "d": ["Any process that activates or increases the frequency, rate or extent of synapse pruning."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0055018", "l": "regulation of cardiac muscle fiber development", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle fiber development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003345", "l": "proepicardium cell migration involved in pericardium morphogenesis", "d": ["The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016099", "l": "monoterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106289", "l": "negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071403", "l": "cellular response to high density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009048", "l": "dosage compensation by inactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0150146", "l": "cell junction disassembly", "d": ["The disaggregation of a cell junction into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901671", "l": "positive regulation of superoxide dismutase activity", "d": ["Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901530", "l": "response to hypochlorite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901710", "l": "regulation of homoserine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of homoserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0031341", "l": "regulation of cell killing", "d": ["Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048627", "l": "myoblast development", "d": ["The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075275", "l": "telium development", "d": ["The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905294", "l": "positive regulation of neural crest cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035862", "l": "dITP metabolic process", "d": ["The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.488569800933099", "identifiers": [{"i": "GO:0045595", "l": "regulation of cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0015838", "l": "amino-acid betaine transport", "d": ["The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075047", "l": "negative regulation of formation by symbiont of haustorium for nutrient acquisition from host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005998", "l": "xylulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902024", "l": "L-histidine transport", "d": ["The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0014729", "l": "regulation of the velocity of shortening of skeletal muscle modulating contraction", "d": ["Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034355", "l": "NAD salvage", "d": ["Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002646", "l": "regulation of central tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of central tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051080", "l": "meiosis II nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes during the second division of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002639", "l": "positive regulation of immunoglobulin production", "d": ["Any process that activates or increases the frequency, rate, or extent of immunoglobulin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:1902969", "l": "mitotic DNA replication", "d": ["Any nuclear DNA replication that is involved in a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:2001242", "l": "regulation of intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905735", "l": "regulation of L-proline import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010513", "l": "positive regulation of phosphatidylinositol biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903936", "l": "cellular response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901969", "l": "positive regulation of polynucleotide 3'-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080001", "l": "mucilage extrusion from seed coat", "d": ["The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000744", "l": "karyogamy involved in conjugation with mutual genetic exchange", "d": ["During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060732", "l": "positive regulation of inositol phosphate biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061805", "l": "mitotic spindle elongation (spindle phase three)", "d": ["The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060954", "l": "neural crest-derived cardiac glial cell development", "d": ["The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060226", "l": "negative regulation of retinal cone cell fate commitment", "d": ["Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0062021", "l": "mitotic cohesin dsDNA (leading strand) loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060329", "l": "cytoplasmic actin-based contraction involved in rearward cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903295", "l": "negative regulation of glutamate secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904826", "l": "regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060586", "l": "multicellular organismal-level iron ion homeostasis", "d": ["A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048190", "l": "wing disc dorsal/ventral pattern formation", "d": ["The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0034976", "l": "response to endoplasmic reticulum stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070383", "l": "DNA cytosine deamination", "d": ["The removal of an amino group from a cytosine residue in DNA, forming a uracil residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006618", "l": "SRP-dependent cotranslational protein targeting to membrane, signal sequence processing", "d": ["The removal of the signal peptide from a nascent protein during cotranslational membrane targeting."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001787", "l": "natural killer cell proliferation", "d": ["The expansion of a natural killer cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044566", "l": "chondrocyte activation", "d": ["A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902518", "l": "response to cyclophosphamide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032696", "l": "negative regulation of interleukin-13 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034299", "l": "reproductive blastospore formation", "d": ["The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901437", "l": "regulation of toluene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of toluene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002618", "l": "positive regulation of macrophage antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002498", "l": "proteolysis within endoplasmic reticulum associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.837549707345602", "identifiers": [{"i": "GO:0018130", "l": "heterocycle biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002863", "l": "positive regulation of inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030538", "l": "embryonic genitalia morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010907", "l": "positive regulation of glucose metabolic process", "d": ["Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003212", "l": "cardiac left atrium morphogenesis", "d": ["The process in which the left cardiac atrium is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002797", "l": "regulation of antibacterial peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140131", "l": "positive regulation of lymphocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060359", "l": "response to ammonium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1990776", "l": "response to angiotensin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0040013", "l": "negative regulation of locomotion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042751", "l": "estivation", "d": ["Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. 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An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120137", "l": "positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0098801", "l": "regulation of renal system process", "d": ["Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030965", "l": "plasma membrane electron transport, NADH to quinone", "d": ["The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072220", "l": "metanephric descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.260233749456212", "identifiers": [{"i": "GO:0044282", "l": "small molecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033373", "l": "maintenance of protease location in mast cell secretory granule", "d": ["A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046073", "l": "dTMP metabolic process", "d": ["The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044633", "l": "modulation of complement activation, alternative pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902111", "l": "response to diethyl maleate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0043277", "l": "apoptotic cell clearance", "d": ["The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904857", "l": "regulation of endothelial cell 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control."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900281", "l": "positive regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048745", "l": "smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030922", "l": "peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine", "d": ["The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902427", "l": "regulation of water channel activity", "d": ["Any process that modulates the frequency, rate or extent of water channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019232", "l": "perception of rate of movement", "d": ["The series of events by which an organism senses the speed and direction of movement of the body and its parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033562", "l": "co-transcriptional gene silencing by RNA interference machinery", "d": ["A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046440", "l": "L-lysine metabolic process", "d": ["The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140744", "l": "negative regulation of lncRNA transcription", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042855", "l": "eugenol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046580", "l": "negative regulation of Ras protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018226", "l": "peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0007391", "l": "dorsal closure", "d": ["The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042206", "l": "halogenated hydrocarbon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048930", "l": "glial cell migration in posterior lateral line nerve", "d": ["The movement of a glial cell along the axons in the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990388", "l": "xylem-to-phloem iron transport", "d": ["The directed movement of iron ions into the phloem from the xylem."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021583", "l": "pons morphogenesis", "d": ["The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003368", "l": "cell-matrix adhesion involved in mesendodermal cell migration", "d": ["The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900112", "l": "regulation of histone H3-K9 trimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030725", "l": "germline ring canal formation", "d": ["Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032497", "l": "detection of lipopolysaccharide", "d": ["The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090410", "l": "malonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051969", "l": "regulation of transmission of nerve impulse", "d": ["Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902771", "l": "positive regulation of choline O-acetyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904109", "l": "positive regulation of cholesterol import", "d": ["Any process that activates or increases the frequency, rate or extent of cholesterol import."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904006", "l": "negative regulation of phospholipase D activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.222260007810753", "identifiers": [{"i": "GO:0071705", "l": "nitrogen compound transport", "d": ["The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0051261", "l": "protein depolymerization", "d": ["The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901830", "l": "zeaxanthin bis(beta-D-glucoside) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0090276", "l": "regulation of peptide hormone secretion", "d": ["Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904075", "l": "positive regulation of trophectodermal cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072716", "l": "response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051364", "l": "N-terminal peptidyl-proline N-formylation", "d": ["The formylation of the N-terminal proline of proteins to form the derivative N-formylproline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097379", "l": "dorsal spinal cord interneuron posterior axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:1901993", "l": "regulation of meiotic cell cycle phase transition", "d": ["Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072723", "l": "cellular response to amitrole", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901329", "l": "regulation of odontoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of odontoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006251", "l": "dCDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903395", "l": "regulation of secondary cell septum biogenesis", "d": ["Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106088", "l": "regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060533", "l": "bronchus cartilage morphogenesis", "d": ["The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110162", "l": "regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010162", "l": "seed dormancy process", "d": ["A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048053", "l": "R1/R6 development", "d": ["The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072062", "l": "proximal convoluted tubule segment 1 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071346", "l": "cellular response to type II interferon", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106134", "l": "positive regulation of cardiac muscle cell contraction", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010337", "l": "regulation of salicylic acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035321", "l": "maintenance of imaginal disc-derived wing hair orientation", "d": ["Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060818", "l": "inactivation of paternal X chromosome by genomic imprinting", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006428", "l": "isoleucyl-tRNA aminoacylation", "d": ["The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043520", "l": "regulation of myosin II filament assembly", "d": ["Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075314", "l": "regulation of basidium development", "d": ["Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905562", "l": "regulation of vascular endothelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106381", "l": "purine deoxyribonucleotide salvage", "d": ["Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019412", "l": "aerobic respiration, using hydrogen as electron donor", "d": ["The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043922", "l": "negative regulation by host of viral transcription", "d": ["Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010825", "l": "positive regulation of centrosome duplication", "d": ["Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009846", "l": "pollen germination", "d": ["The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905951", "l": "mitochondrion DNA recombination", "d": ["Any DNA recombination that takes place in mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106246", "l": "regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014052", "l": "regulation of gamma-aminobutyric acid secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014040", "l": "positive regulation of Schwann cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141059", "l": "disruption of host antimicrobial peptide activity", "d": ["Any process in which a symbiont interferes with a host antimicrobial peptide, for example by cleavage or degredation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015946", "l": "methanol oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009811", "l": "stilbene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046202", "l": "cyanide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160023", "l": "sneeze reflex", "d": ["A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015797", "l": "mannitol transmembrane transport", "d": ["The directed movement of mannitol across a membrane. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006881", "l": "extracellular sequestering of iron ion", "d": ["The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033635", "l": "modulation by symbiont of host response to abiotic stimulus", "d": ["Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048717", "l": "anterior cibarial plate morphogenesis", "d": ["The process in which the anatomical structures of the anterior cibarial plate are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0002168", "l": "instar larval development", "d": ["The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0060811", "l": "intracellular mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000836", "l": "positive regulation of androgen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androgen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031915", "l": "positive regulation of synaptic plasticity", "d": ["A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010653", "l": "negative regulation of cell communication by chemical coupling", "d": ["Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0090305", "l": "nucleic acid phosphodiester bond hydrolysis", "d": ["The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045741", "l": "positive regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035293", "l": "chitin-based larval cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060391", "l": "positive regulation of SMAD protein signal transduction", "d": ["Any process that increases the rate, frequency or extent of SMAD protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0035195", "l": "miRNA-mediated post-transcriptional gene silencing", "d": ["A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010172", "l": "embryonic body morphogenesis", "d": ["The process in which the anatomical structures of the embryonic soma are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904042", "l": "negative regulation of cystathionine beta-synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904547", "l": "regulation of cellular response to glucose starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to glucose starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0120316", "l": "sperm flagellum assembly", "d": ["The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001107", "l": "negative regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098925", "l": "retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission", "d": ["Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001407", "l": "glycerophosphodiester transmembrane transport", "d": ["The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0019674", "l": "NAD metabolic process", "d": ["The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043059", "l": "regulation of forward locomotion", "d": ["Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0050714", "l": "positive regulation of protein secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071471", "l": "cellular response to non-ionic osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019385", "l": "methanogenesis, from acetate", "d": ["The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060770", "l": "negative regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010610", "l": "regulation of mRNA stability involved in response to stress", "d": ["Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097531", "l": "mast cell migration", "d": ["The movement of a mast cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016318", "l": "ommatidial rotation", "d": ["The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000865", "l": "negative regulation of estradiol secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014828", "l": "distal stomach smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0006558", "l": "L-phenylalanine metabolic process", "d": ["The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902191", "l": "2-methylbutanoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018336", "l": "peptidyl-tyrosine hydroxylation", "d": ["The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0042092", "l": "type 2 immune response", "d": ["An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902984", "l": "pre-replicative complex assembly involved in premeiotic DNA replication", "d": ["Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002908", "l": "regulation of peripheral B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of peripheral B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0046660", "l": "female sex differentiation", "d": ["The establishment of the sex of a female organism by physical differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0052548", "l": "regulation of endopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071647", "l": "negative regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061621", "l": "canonical glycolysis", "d": ["The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. 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It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010602", "l": "regulation of 1-aminocyclopropane-1-carboxylate metabolic process", "d": ["Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905655", "l": "negative regulation of artery smooth muscle contraction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0002313", "l": "mature B cell differentiation involved in immune response", "d": ["The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901275", "l": "tartrate metabolic process", "d": ["The chemical reactions and pathways involving tartrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021709", "l": "cerebellar basket cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006684", "l": "sphingomyelin metabolic process", "d": ["The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071271", "l": "1-butanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0140115", "l": "export across plasma membrane", "d": ["The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045618", "l": "positive regulation of keratinocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051627", "l": "negative regulation of epinephrine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.517713470395833", "identifiers": [{"i": "GO:1901568", "l": "fatty acid derivative metabolic process", "d": ["The chemical reactions and pathways involving fatty acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0140253", "l": "cell-cell fusion", "d": ["A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006216", "l": "cytidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046114", "l": "guanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905463", "l": "negative regulation of DNA duplex unwinding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042425", "l": "choline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071171", "l": "site-specific DNA replication termination at RTS1 barrier", "d": ["A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900278", "l": "positive regulation of proteinase activated receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902748", "l": "positive regulation of lens fiber cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015717", "l": "triose phosphate transport", "d": ["The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140500", "l": "regulation of reticulophagy", "d": ["Any process that modulates the frequency, rate or extent of reticulophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046579", "l": "positive regulation of Ras protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904875", "l": "regulation of DNA ligase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905312", "l": "positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046216", "l": "indole phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007418", "l": "ventral midline development", "d": ["The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001507", "l": "acetylcholine catabolic process in synaptic cleft", "d": ["The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097275", "l": "intracellular ammonium homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900028", "l": "negative regulation of ruffle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061926", "l": "positive regulation of formation of radial glial scaffolds", "d": ["Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034141", "l": "positive regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032669", "l": "regulation of interleukin-25 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-25 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001924", "l": "regulation of B-1 B cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0021781", "l": "glial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061104", "l": "adrenal chromaffin cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140250", "l": "regulation protein catabolic process at synapse", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990959", "l": "eosinophil homeostasis", "d": ["The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010792", "l": "DNA double-strand break processing involved in repair via single-strand annealing", "d": ["The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032455", "l": "nerve growth factor processing", "d": ["The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010514", "l": "induction of conjugation with cellular fusion", "d": ["The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.071335352100078", "identifiers": [{"i": "GO:0042698", "l": "ovulation cycle", "d": ["The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001552", "l": "ovarian follicle atresia", "d": ["A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002667", "l": "regulation of T cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of T cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048767", "l": "root hair elongation", "d": ["The process in which the root hair grows longer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036514", "l": "dopaminergic neuron axon guidance", "d": ["The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007371", "l": "ventral midline determination", "d": ["The regionalization process in which the area where the ventral midline will form is specified."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070859", "l": "positive regulation of bile acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034122", "l": "negative regulation of toll-like receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006425", "l": "glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035624", "l": "receptor transactivation", "d": ["The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003243", "l": "circumferential growth involved in left ventricle morphogenesis", "d": ["The morphogenetic growth in which the left ventricle grows expanding its external boundary."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900155", "l": "negative regulation of bone trabecula formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0009311", "l": "oligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072584", "l": "caveolin-mediated endocytosis", "d": ["An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034496", "l": "multivesicular body membrane disassembly", "d": ["The controlled breakdown of the membranes of multivesicular bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106426", "l": "regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of tge kainate selective glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140879", "l": "conidiogenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061070", "l": "female urethra development", "d": ["The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090315", "l": "negative regulation of protein targeting to membrane", "d": ["Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018339", "l": "peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid", "d": ["The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901116", "l": "cephamycin C metabolic process", "d": ["The chemical reactions and pathways involving cephamycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097333", "l": "response to olanzapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048034", "l": "heme O biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070777", "l": "D-aspartate transport", "d": ["The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "34.889241718715965", "identifiers": [{"i": "GO:0007154", "l": "cell communication", "d": ["Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071951", "l": "conversion of methionyl-tRNA to N-formyl-methionyl-tRNA", "d": ["The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019686", "l": "purine nucleoside interconversion", "d": ["The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006673", "l": "inositol phosphoceramide metabolic process", "d": ["The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044804", "l": "nucleophagy", "d": ["A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019499", "l": "cyanide metabolic process", "d": ["The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. 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Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042306", "l": "regulation of protein import into nucleus", "d": ["Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007540", "l": "sex determination, establishment of X:A ratio", "d": ["The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090679", "l": "cell differentiation involved in phenotypic switching", "d": ["A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.211190354407904", "identifiers": [{"i": "GO:0002263", "l": "cell activation involved in immune response", "d": ["A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106042", "l": "negative regulation of GABA-A receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090352", "l": "regulation of nitrate assimilation", "d": ["Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052024", "l": "positive regulation by symbiont of hormone or growth regulator levels in host", "d": ["The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032882", "l": "regulation of chitin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060135", "l": "maternal process involved in female pregnancy", "d": ["A reproductive process occurring in the mother that allows an embryo or fetus to develop within it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019664", "l": "mixed acid fermentation", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030310", "l": "poly-N-acetyllactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021818", "l": "modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration", "d": ["The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021747", "l": "cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048446", "l": "petal morphogenesis", "d": ["The process in which the anatomical structures of the petal are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.811621335125167", "identifiers": [{"i": "GO:0030001", "l": "metal ion transport", "d": ["The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0006302", "l": "double-strand break repair", "d": ["The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0036267", "l": "invasive filamentous growth", "d": ["The growth of colonies in filamentous chains of cells into a substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071371", "l": "cellular response to gonadotropin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021639", "l": "trochlear nerve morphogenesis", "d": ["The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902877", "l": "positive regulation of embryonic pattern specification", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic pattern specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0007064", "l": "mitotic sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0007435", "l": "salivary gland morphogenesis", "d": ["The process in which the anatomical structures of the salivary gland are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032540", "l": "positive regulation of host-seeking behavior", "d": ["Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002019", "l": "regulation of renal output by angiotensin", "d": ["The process in which angiotensin directly modulates the rate of urine output by the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904723", "l": "negative regulation of Wnt-Frizzled-LRP5/6 complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060148", "l": "positive regulation of post-transcriptional gene silencing", "d": ["Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902210", "l": "positive regulation of bacterial-type flagellum assembly", "d": ["Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902692", "l": "regulation of neuroblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of neuroblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022015", "l": "radial glial cell division in pallium", "d": ["The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090230", "l": "regulation of centromere complex assembly", "d": ["Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901963", "l": "regulation of cell proliferation involved in outflow tract morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006235", "l": "dTTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044726", "l": "epigenetic programing of female pronucleus", "d": ["The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048819", "l": "regulation of hair follicle maturation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000111", "l": "positive regulation of macrophage apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015968", "l": "stringent response", "d": ["A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904160", "l": "protein localization to chloroplast starch grain", "d": ["A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030002", "l": "intracellular monoatomic anion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.421156191289441", "identifiers": [{"i": "GO:0006139", "l": "nucleobase-containing compound metabolic process", "d": ["Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0001570", "l": "vasculogenesis", "d": ["The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010813", "l": "neuropeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:1905475", "l": "regulation of protein localization to membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031450", "l": "negative regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048025", "l": "negative regulation of mRNA splicing, via spliceosome", "d": ["Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090421", "l": "embryonic meristem initiation", "d": ["Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900711", "l": "negative regulation of tensidol B biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071472", "l": "cellular response to salt stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055019", "l": "negative regulation of cardiac muscle fiber development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.998193119084064", "identifiers": [{"i": "GO:0048705", "l": "skeletal system morphogenesis", "d": ["The process in which the anatomical structures of the skeleton are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021681", "l": "cerebellar granular layer development", "d": ["The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0001677", "l": "formation of translation initiation ternary complex", "d": ["Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046211", "l": "(+)-camphor biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046141", "l": "corrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0060444", "l": "branching involved in mammary gland duct morphogenesis", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046453", "l": "dipyrrin metabolic process", "d": ["The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090119", "l": "vesicle-mediated cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0002685", "l": "regulation of leukocyte migration", "d": ["Any process that modulates the frequency, rate, or extent of leukocyte migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901571", "l": "fatty acid derivative transport", "d": ["The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110055", "l": "negative regulation of actin filament annealing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120222", "l": "regulation of blastocyst development", "d": ["Any process that modulates the frequency, rate or extent of blastocyst development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903907", "l": "negative regulation of plasma membrane raft polarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071569", "l": "protein ufmylation", "d": ["Covalent attachment of the ubiquitin-like protein UFM1 to another protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032623", "l": "interleukin-2 production", "d": ["The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061107", "l": "seminal vesicle development", "d": ["The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090089", "l": "regulation of dipeptide transport", "d": ["Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903647", "l": "negative regulation of chlorophyll catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032645", "l": "regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097501", "l": "stress response to metal ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0060541", "l": "respiratory system development", "d": ["The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990227", "l": "paranodal junction maintenance", "d": ["The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010892", "l": "positive regulation of mitochondrial translation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0035196", "l": "miRNA processing", "d": ["A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905335", "l": "regulation of aggrephagy", "d": ["Any process that modulates the frequency, rate or extent of aggrephagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098972", "l": "anterograde dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903723", "l": "negative regulation of centriole elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 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tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044387", "l": "negative regulation of protein kinase activity by regulation of protein phosphorylation", "d": ["The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015835", "l": "peptidoglycan transport", "d": ["The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010134", "l": "sulfate assimilation via adenylyl sulfate reduction", "d": ["The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the 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mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055089", "l": "fatty acid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019801", "l": "cyclization of asparagine involved in intein-mediated protein splicing", "d": ["The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0009798", "l": "axis specification", "d": ["The establishment, maintenance and elaboration of a pattern along a line or around a point."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0045493", "l": "xylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051124", "l": "synaptic assembly at neuromuscular junction", "d": ["The assembly of a synapse at a neuromuscular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010045", "l": "response to nickel cation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051154", "l": "negative regulation of striated muscle cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048659", "l": "smooth muscle cell proliferation", "d": ["The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021951", "l": "chemoattraction involved in precerebellar neuron migration", "d": ["The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.431355563592696", "identifiers": [{"i": "GO:0022414", "l": "reproductive process", "d": ["A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902465", "l": "negative regulation of histone H3-K27 trimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039018", "l": "nephrostome development", "d": ["The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018357", "l": "protein-phycourobilin linkage via phycourobilin-bis-L-cysteine", "d": ["The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060080", "l": "inhibitory postsynaptic potential", "d": ["A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. 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An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000451", "l": "rRNA 2'-O-methylation", "d": ["The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036076", "l": "ligamentous ossification", "d": ["Ossification wherein bone tissue forms within ligamentous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010116", "l": "positive regulation of abscisic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903931", "l": "positive regulation of pyrimidine-containing compound salvage", "d": ["Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090279", "l": "regulation of calcium ion import", "d": ["Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014883", "l": "transition between fast and slow fiber", "d": ["The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072708", "l": "response to sorbitol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060265", "l": "positive regulation of respiratory burst involved in inflammatory response", "d": ["Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0003197", "l": "endocardial cushion development", "d": ["The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032804", "l": "negative regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990394", "l": "cellular response to cell wall damage", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903660", "l": "negative regulation of complement-dependent cytotoxicity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.618371369379382", "identifiers": [{"i": "GO:0007269", "l": "neurotransmitter secretion", "d": ["The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1904823", "l": "purine nucleobase transmembrane transport", "d": ["The process in which a purine nucleobase is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002492", "l": "peptide antigen assembly with MHC class Ib protein complex", "d": ["The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010442", "l": "guard cell morphogenesis", "d": ["Generation and organization of the polarized cell that is capable of turgor driven movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021572", "l": "rhombomere 6 development", "d": ["The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:0045833", "l": "negative regulation of lipid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060358", "l": "negative regulation of leucine import", "d": ["Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001113", "l": "negative regulation of cellular response to hepatocyte growth factor stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902639", "l": "propan-2-ol metabolic process", "d": ["The chemical reactions and pathways involving propan-2-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000855", "l": "regulation of mineralocorticoid secretion", "d": ["Any process that modulates the frequency, rate or extent of mineralocorticoid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160006", "l": "Fc receptor-mediated immune complex endocytosis", "d": ["An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044407", "l": "single-species biofilm formation in or on host organism", "d": ["A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035907", "l": "dorsal aorta development", "d": ["The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0050433", "l": "regulation of catecholamine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of catecholamines."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0021510", "l": "spinal cord development", "d": ["The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090313", "l": "regulation of protein targeting to membrane", "d": ["Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045962", "l": "positive regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0014014", "l": "negative regulation of gliogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900149", "l": "positive regulation of Schwann cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006043", "l": "glucosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046210", "l": "nitric oxide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0048749", "l": "compound eye development", "d": ["The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014007", "l": "negative regulation of microglia differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.312708028507217", "identifiers": [{"i": "GO:0006939", "l": "smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014873", "l": "response to muscle activity involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009959", "l": "negative gravitropism", "d": ["The orientation of plant parts away from gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035524", "l": "proline transmembrane transport", "d": ["The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010606", "l": "positive regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098816", "l": "mini excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046265", "l": "thiocyanate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901052", "l": "sarcosine metabolic process", "d": ["The chemical reactions and pathways involving sarcosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900886", "l": "positive regulation of tridecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0060411", "l": "cardiac septum morphogenesis", "d": ["The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903234", "l": "negative regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900504", "l": "negative regulation of cellulosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006669", "l": "sphinganine-1-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904737", "l": "positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:2001251", "l": "negative regulation of chromosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035873", "l": "lactate transmembrane transport", "d": ["The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0014829", "l": "vascular associated smooth muscle contraction", "d": ["A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1990571", "l": "meiotic centromere clustering", "d": ["The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902129", "l": "(-)-lariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (-)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0060021", "l": "roof of mouth development", "d": ["The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110021", "l": "cardiac muscle myoblast proliferation", "d": ["The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048106", "l": "establishment of thoracic bristle planar orientation", "d": ["Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061191", "l": "positive regulation of vacuole fusion, non-autophagic", "d": ["Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021732", "l": "midbrain-hindbrain boundary maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009155", "l": "purine deoxyribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097376", "l": "interneuron axon guidance", "d": ["The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001796", "l": "regulation of type IIa hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097054", "l": "L-glutamate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905003", "l": "picolinic acid metabolic process", "d": ["The chemical reactions and pathways involving picolinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900384", "l": "regulation of flavonol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of flavonol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.206455864469035", "identifiers": [{"i": "GO:0009719", "l": "response to endogenous stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035895", "l": "modulation of mast cell degranulation in another organism", "d": ["Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051299", "l": "centrosome separation", "d": ["The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098904", "l": "regulation of AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903899", "l": "positive regulation of PERK-mediated unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070424", "l": "regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045983", "l": "positive regulation of purine nucleobase metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031116", "l": "positive regulation of microtubule polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.116718332021435", "identifiers": [{"i": "GO:0031323", "l": "regulation of cellular metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1901656", "l": "glycoside transport", "d": ["The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030501", "l": "positive regulation of bone mineralization", "d": ["Any process that activates or increases the frequency, rate or extent of bone mineralization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990046", "l": "stress-induced mitochondrial fusion", "d": ["Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038176", "l": "positive regulation of SREBP signaling pathway in response to decreased oxygen levels", "d": ["Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097428", "l": "protein maturation by iron-sulfur cluster transfer", "d": ["The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032705", "l": "negative regulation of interleukin-21 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019046", "l": "release from viral latency", "d": ["The process by which a virus begins to replicate following a latency replication decision (switch)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045656", "l": "negative regulation of monocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903888", "l": "regulation of plant epidermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:2000736", "l": "regulation of stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0015766", "l": "disaccharide transport", "d": ["The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033524", "l": "sinapate ester metabolic process", "d": ["The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021727", "l": "intermediate reticular formation development", "d": ["The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099001", "l": "viral genome ejection through host cell envelope, long flexible tail mechanism", "d": ["Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0003321", "l": "positive regulation of blood pressure by epinephrine-norepinephrine", "d": ["Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003305", "l": "cell migration involved in heart jogging", "d": ["The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003148", "l": "outflow tract septum morphogenesis", "d": ["The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009261", "l": "ribonucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033538", "l": "ajugose biosynthetic process using galactan:galactan galactosyltransferase", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032976", "l": "release of matrix enzymes from mitochondria", "d": ["The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903063", "l": "negative regulation of reverse cholesterol transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0160033", "l": "regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that modulates the frequency, rate or extent of the Toll receptor ligand protein activation cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035633", "l": "maintenance of blood-brain barrier", "d": ["Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010916", "l": "negative regulation of very-low-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0019883", "l": "antigen processing and presentation of endogenous antigen", "d": ["The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019245", "l": "D(-)-lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036034", "l": "mediator complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.084299901261197", "identifiers": [{"i": "GO:0002507", "l": "tolerance induction", "d": ["A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905309", "l": "positive regulation of cohesin loading", "d": ["Any process that activates or increases the frequency, rate or extent of cohesin loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098825", "l": "peptidyl-histidine guanylation", "d": ["The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097318", "l": "invasive growth in response to abiotic stimulus", "d": ["The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900814", "l": "monodictyphenone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of monodictyphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019337", "l": "tetrachloroethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048619", "l": "embryonic hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0070482", "l": "response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0001764", "l": "neuron migration", "d": ["The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070291", "l": "N-acylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090423", "l": "phytochelatin-metal complex formation", "d": ["A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072279", "l": "convergent extension involved in metanephric nephron morphogenesis", "d": ["The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060700", "l": "regulation of ribonuclease activity", "d": ["Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034224", "l": "cellular response to zinc ion starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070197", "l": "meiotic attachment of telomere to nuclear envelope", "d": ["The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097282", "l": "immunoglobulin-mediated neutralization", "d": ["The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010835", "l": "regulation of protein ADP-ribosylation", "d": ["Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900055", "l": "regulation of leaf senescence", "d": ["Any process that modulates the frequency, rate or extent of leaf senescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0044062", "l": "regulation of excretion", "d": ["Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045879", "l": "negative regulation of smoothened signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:2001234", "l": "negative regulation of apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902233", "l": "negative regulation of positive thymic T cell selection", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0018157", "l": "peptide cross-linking via an oxazole or thiazole", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043945", "l": "positive regulation of asexual sporulation resulting in formation of a cellular spore", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045186", "l": "zonula adherens assembly", "d": ["Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1903649", "l": "regulation of cytoplasmic transport", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0046034", "l": "ATP metabolic process", "d": ["The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048796", "l": "swim bladder maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902332", "l": "bacterial-type DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding that is involved in bacterial-type DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0060810", "l": "intracellular mRNA localization involved in pattern specification process", "d": ["Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1900909", "l": "negative regulation of olefin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021856", "l": "hypothalamic tangential migration using cell-axon interactions", "d": ["The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070243", "l": "regulation of thymocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of thymocyte death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010549", "l": "regulation of membrane disassembly", "d": ["Any process that modulates the frequency, rate or extent of membrane disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035165", "l": "embryonic crystal cell differentiation", "d": ["The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019988", "l": "charged-tRNA amino acid modification", "d": ["The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035530", "l": "chemokine (C-C motif) ligand 6 production", "d": ["The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018341", "l": "peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine", "d": ["The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903282", "l": "regulation of glutathione peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of glutathione peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903189", "l": "glyoxal metabolic process", "d": ["The chemical reactions and pathways involving glyoxal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021668", "l": "rhombomere 6 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071879", "l": "positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0016101", "l": "diterpenoid metabolic process", "d": ["The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010310", "l": "regulation of hydrogen peroxide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033052", "l": "cyanoamino acid metabolic process", "d": ["The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052162", "l": "modulation by symbiont of defense-related host calcium ion flux", "d": ["Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090465", "l": "intracellular arginine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of arginine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0016322", "l": "neuron remodeling", "d": ["The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002121", "l": "inter-male aggressive behavior", "d": ["Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901867", "l": "ecgonine methyl ester metabolic process", "d": ["The chemical reactions and pathways involving ecgonine methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021748", "l": "dorsal cochlear nucleus development", "d": ["The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046385", "l": "deoxyribose phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0140718", "l": "facultative heterochromatin formation", "d": ["The compaction of chromatin into a conformation that is refactory to transcription but that be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000797", "l": "regulation of amniotic stem cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0042129", "l": "regulation of T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:0046890", "l": "regulation of lipid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097289", "l": "alpha-ribazole metabolic process", "d": ["The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035394", "l": "regulation of chemokine (C-X-C motif) ligand 9 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009150", "l": "purine ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009394", "l": "2'-deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0043523", "l": "regulation of neuron apoptotic process", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090322", "l": "regulation of superoxide metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902498", "l": "regulation of protein autoubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein autoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0001656", "l": "metanephros development", "d": ["The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903341", "l": "regulation of meiotic DNA double-strand break formation", "d": ["Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0034091", "l": "regulation of maintenance of sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034247", "l": "snoRNA splicing", "d": ["The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072072", "l": "kidney stroma development", "d": ["The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045014", "l": "carbon catabolite repression of transcription by glucose", "d": ["A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043150", "l": "DNA synthesis involved in double-strand break repair via homologous recombination", "d": ["The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060116", "l": "vestibular receptor cell morphogenesis", "d": ["Any process that alters the size or shape of a vestibular receptor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000246", "l": "positive regulation of FtsZ-dependent cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010666", "l": "positive regulation of cardiac muscle cell apoptotic process", "d": ["Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048672", "l": "positive regulation of collateral sprouting", "d": ["Any process that activates or increases the frequency, rate or extent of collateral sprouting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905534", "l": "positive regulation of leucine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1901018", "l": "positive regulation of potassium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0090101", "l": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120271", "l": "negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018057", "l": "peptidyl-lysine oxidation", "d": ["The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0045187", "l": "regulation of circadian sleep/wake cycle, sleep", "d": ["Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034037", "l": "purine ribonucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900912", "l": "negative regulation of olefin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036321", "l": "ghrelin secretion", "d": ["The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002540", "l": "leukotriene production involved in inflammatory response", "d": ["The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000307", "l": "regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001304", "l": "lipoxin B4 metabolic process", "d": ["The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120182", "l": "regulation of focal adhesion disassembly", "d": ["Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030592", "l": "DNA ADP-ribosylation", "d": ["The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045115", "l": "regulation of beta 2 integrin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098705", "l": "copper ion import across plasma membrane", "d": ["The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010830", "l": "regulation of myotube differentiation", "d": ["Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045968", "l": "negative regulation of juvenile hormone biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903369", "l": "negative regulation of foraging behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0014897", "l": "striated muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0015908", "l": "fatty acid transport", "d": ["The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0050769", "l": "positive regulation of neurogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032248", "l": "positive regulation of purine nucleoside transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035887", "l": "aortic smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098873", "l": "neuronal action potential back-propagation", "d": ["Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043415", "l": "positive regulation of skeletal muscle tissue regeneration", "d": ["Any process that activates or increase the rate of skeletal muscle regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110043", "l": "positive regulation of pharynx morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044319", "l": "wound healing, spreading of cells", "d": ["The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106101", "l": "ER-dependent peroxisome localization", "d": ["A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048207", "l": "vesicle targeting, rough ER to cis-Golgi", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036051", "l": "protein localization to trailing edge", "d": ["A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046697", "l": "decidualization", "d": ["The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090055", "l": "positive regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that increases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072106", "l": "regulation of ureteric bud formation", "d": ["Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904806", "l": "regulation of protein oxidation", "d": ["Any process that modulates the frequency, rate or extent of protein oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009662", "l": "etioplast organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016562", "l": "protein import into peroxisome matrix, receptor recycling", "d": ["The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140885", "l": "suppression by virus of host type III interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type III interferon-mediated signaling in the host organism. Type III interferon is also known as interferon-lambda."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904404", "l": "response to formaldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:2000181", "l": "negative regulation of blood vessel morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061003", "l": "positive regulation of dendritic spine morphogenesis", "d": ["Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045853", "l": "negative regulation of bicoid mRNA localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009270", "l": "response to humidity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.930558860186586", "identifiers": [{"i": "GO:0048878", "l": "chemical homeostasis", "d": ["Any biological process involved in the maintenance of an internal steady state of a chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901906", "l": "diadenosine pentaphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine pentaphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014825", "l": "stomach fundus smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905434", "l": "positive regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0061389", "l": "regulation of direction of cell growth", "d": ["Any process that modulates the direction of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002891", "l": "positive regulation of immunoglobulin mediated immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018441", "l": "iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide", "d": ["The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006117", "l": "acetaldehyde metabolic process", "d": ["The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0085032", "l": "pertubation of host canonical NF-kappaB cascade", "d": ["A process in which a symbiont alters or subverts a canonical NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000488", "l": "positive regulation of brassinosteroid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0009806", "l": "lignan metabolic process", "d": ["The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035128", "l": "post-embryonic forelimb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:1901654", "l": "response to ketone", "d": ["A response that results in a state of tolerance to ketone."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0098711", "l": "iron ion import across plasma membrane", "d": ["The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000706", "l": "negative regulation of dense core granule biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031064", "l": "negative regulation of histone deacetylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043174", "l": "nucleoside salvage", "d": ["Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071719", "l": "sodium-independent leukotriene transport", "d": ["The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000972", "l": "positive regulation of detection of glucose", "d": ["Any process that activates or increases the frequency, rate or extent of detection of glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033331", "l": "ent-kaurene metabolic process", "d": ["The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.20186355550635", "identifiers": [{"i": "GO:0002526", "l": "acute inflammatory response", "d": ["Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905767", "l": "regulation of double-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062052", "l": "starch granule initiation", "d": ["The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061386", "l": "closure of optic fissure", "d": ["The closure of the temporary ventral gap in the optic cup that contributes to its shaping."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048089", "l": "regulation of female pigmentation", "d": ["Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0045912", "l": "negative regulation of carbohydrate metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905758", "l": "positive regulation of primary cell septum biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001109", "l": "promoter clearance during DNA-templated transcription", "d": ["Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002931", "l": "response to ischemia", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902153", "l": "regulation of response to DNA damage checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010624", "l": "regulation of Schwann cell proliferation", "d": ["Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000700", "l": "positive regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044321", "l": "response to leptin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019381", "l": "atrazine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903138", "l": "negative regulation of cell wall integrity MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0012502", "l": "induction of programmed cell death", "d": ["A process which directly activates any of the steps required for programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0045861", "l": "negative regulation of proteolysis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046720", "l": "citric acid secretion", "d": ["The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019311", "l": "sorbose metabolic process", "d": ["The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003095", "l": "pressure natriuresis", "d": ["The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904088", "l": "positive regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902424", "l": "negative regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046946", "l": "hydroxylysine metabolic process", "d": ["The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043051", "l": "regulation of pharyngeal pumping", "d": ["Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905850", "l": "positive regulation of forward locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of forward locomotion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090051", "l": "negative regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.308852722163607", "identifiers": [{"i": "GO:0009889", "l": "regulation of biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902200", "l": "3-methylbut-2-enoyl-CoA(4-) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048484", "l": "enteric nervous system development", "d": ["The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018244", "l": "protein N-linked glycosylation via tryptophan", "d": ["The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905923", "l": "positive regulation of acetylcholine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046040", "l": "IMP metabolic process", "d": ["The chemical reactions and pathways involving IMP, inosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2001104", "l": "heptasaccharide transport", "d": ["The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900141", "l": "regulation of oligodendrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061519", "l": "macrophage homeostasis", "d": ["The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032276", "l": "regulation of gonadotropin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905116", "l": "positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002149", "l": "hypochlorous acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypochlorous acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052324", "l": "plant-type cell wall cellulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902141", "l": "cellular response to inositol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090084", "l": "negative regulation of inclusion body assembly", "d": ["Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903332", "l": "regulation of protein folding", "d": ["Any process that modulates the frequency, rate or extent of protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070954", "l": "negative regulation of neutrophil mediated cytotoxicity", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018426", "l": "O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0043632", "l": "modification-dependent macromolecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000953", "l": "positive regulation of xyloglucan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018083", "l": "peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine", "d": ["The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034155", "l": "regulation of toll-like receptor 7 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902638", "l": "neural crest cell differentiation involved in parathyroid gland development", "d": ["Any neural crest cell differentiation that is involved in parathyroid gland development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052131", "l": "positive aerotaxis", "d": ["The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043155", "l": "negative regulation of photosynthesis, light reaction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140878", "l": "griseofulvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016269", "l": "O-glycan processing, core 3", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010159", "l": "specification of animal organ position", "d": ["The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902681", "l": "regulation of replication fork arrest at rDNA repeats", "d": ["Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905563", "l": "negative regulation of vascular endothelial cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030255", "l": "protein secretion by the type IV secretion system", "d": ["The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900291", "l": "regulation of galactotriose transport", "d": ["Any process that modulates the frequency, rate or extent of galactotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072417", "l": "response to spindle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of spindle checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035963", "l": "cellular response to interleukin-13", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010989", "l": "negative regulation of low-density lipoprotein particle clearance", "d": ["Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.731230465243208", "identifiers": [{"i": "GO:0006954", "l": "inflammatory response", "d": ["The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001264", "l": "negative regulation of C-C chemokine binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042815", "l": "bipolar cell growth", "d": ["The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090217", "l": "negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity", "d": ["Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090096", "l": "positive regulation of metanephric cap mesenchymal cell proliferation", "d": ["Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0009273", "l": "peptidoglycan-based cell wall biogenesis", "d": ["The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071233", "l": "cellular response to leucine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.769355763942954", "identifiers": [{"i": "GO:0040029", "l": "epigenetic regulation of gene expression", "d": ["A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080127", "l": "fruit septum development", "d": ["The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042355", "l": "L-fucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904582", "l": "positive regulation of intracellular mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061000", "l": "negative regulation of dendritic spine development", "d": ["Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019408", "l": "dolichol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.528458322397171", "identifiers": [{"i": "GO:0035821", "l": "modulation of process of another organism", "d": ["The process in which an organism effects a change in the structure or processes of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046312", "l": "phosphoarginine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055004", "l": "atrial cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1902570", "l": "protein localization to nucleolus", "d": ["A process in which a protein is transported to, or maintained in, a location within a nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900712", "l": "positive regulation of tensidol B biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070831", "l": "basement membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904595", "l": "positive regulation of termination of RNA polymerase II transcription", "d": ["Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0100008", "l": "regulation of fever generation by prostaglandin biosynthetic process", "d": ["Any prostaglandin biosynthetic process process that regulates fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006589", "l": "octopamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120008", "l": "positive regulation of glutamatergic neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031287", "l": "positive regulation of sorocarp stalk cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901763", "l": "oxytetracycline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxytetracycline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905422", "l": "negative regulation of plant organ morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905009", "l": "negative regulation of L-lysine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0072132", "l": "mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060369", "l": "positive regulation of Fc receptor mediated stimulatory signaling pathway", "d": ["Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000478", "l": "positive regulation of metanephric podocyte development", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061978", "l": "mandibular condyle articular cartilage development", "d": ["The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900230", "l": "positive regulation of single-species biofilm formation in or on host organism", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010696", "l": "positive regulation of mitotic spindle pole body separation", "d": ["Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071395", "l": "cellular response to jasmonic acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007458", "l": "progression of morphogenetic furrow involved in compound eye morphogenesis", "d": ["The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070304", "l": "positive regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140249", "l": "protein catabolic process at postsynapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0099172", "l": "presynapse organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0098840", "l": "protein transport along microtubule", "d": ["The directed movement of a protein along a microtubule, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0042278", "l": "purine nucleoside metabolic process", "d": ["The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006301", "l": "postreplication repair", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021616", "l": "glossopharyngeal nerve formation", "d": ["The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140409", "l": "positive regulation of mRNA alternative polyadenylation", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002045", "l": "regulation of cell adhesion involved in intussusceptive angiogenesis", "d": ["The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048143", "l": "astrocyte activation", "d": ["A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000160", "l": "negative regulation of planar cell polarity pathway involved in heart morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903839", "l": "positive regulation of mRNA 3'-UTR binding", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0045851", "l": "pH reduction", "d": ["Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044471", "l": "envenomation resulting in pore formation in membrane of another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060302", "l": "negative regulation of cytokine activity", "d": ["Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090082", "l": "positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990514", "l": "5' transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019741", "l": "pentacyclic triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042046", "l": "W-molybdopterin cofactor metabolic process", "d": ["The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140280", "l": "negative regulation of mitotic division septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010120", "l": "camalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0010975", "l": "regulation of neuron projection development", "d": ["Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900596", "l": "(+)-kotanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-kotanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106036", "l": "assembly of apicomedial cortex actomyosin", "d": ["A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019099", "l": "female germ-line sex determination", "d": ["The determination of sex and sexual phenotype in a female organism's germ line."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090327", "l": "negative regulation of locomotion involved in locomotory behavior", "d": ["Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0044784", "l": "metaphase/anaphase transition of cell cycle", "d": ["The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033544", "l": "fatty acid beta-oxidation, unsaturated, even number, epimerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1904729", "l": "regulation of intestinal lipid absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal lipid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071455", "l": "cellular response to hyperoxia", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061721", "l": "6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009787", "l": "regulation of abscisic acid-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904451", "l": "regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051461", "l": "positive regulation of corticotropin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010227", "l": "floral organ abscission", "d": ["The controlled shedding of floral organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052091", "l": "modulation of nutrient release by host", "d": ["Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.059531638367481", "identifiers": [{"i": "GO:0040007", "l": "growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050434", "l": "positive regulation of viral transcription", "d": ["Any process that activates or increases the frequency, rate or extent of viral transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032690", "l": "negative regulation of interleukin-1 alpha production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003235", "l": "sinus venosus development", "d": ["The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035161", "l": "imaginal disc lineage restriction", "d": ["Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0021544", "l": "subpallium development", "d": ["The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006532", "l": "aspartate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071223", "l": "cellular response to lipoteichoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905901", "l": "positive regulation of smooth muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0001522", "l": "pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine within an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032215", "l": "positive regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0000154", "l": "rRNA modification", "d": ["The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021891", "l": "olfactory bulb interneuron development", "d": ["The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080093", "l": "regulation of photorespiration", "d": ["Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035522", "l": "monoubiquitinated histone H2A deubiquitination", "d": ["The removal of the ubiquitin group from a monoubiquitinated histone H2A protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.100229552557821", "identifiers": [{"i": "GO:0060284", "l": "regulation of cell development", "d": ["Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044080", "l": "perturbation of host cGMP-mediated signal transduction", "d": ["A process in which a symbiont alters or subverts a cGMP-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900850", "l": "negative regulation of pseurotin A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097251", "l": "leukotriene B4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0090022", "l": "regulation of neutrophil chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0031344", "l": "regulation of cell projection organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046014", "l": "negative regulation of T cell homeostatic proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904569", "l": "regulation of selenocysteine incorporation", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine incorporation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048814", "l": "regulation of dendrite morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of dendrite morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080169", "l": "cellular response to boron-containing substance deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106354", "l": "tRNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901783", "l": "p-cumate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cumate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090719", "l": "adaptive immune effector response involving T cells and B lineage cells", "d": ["An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990001", "l": "inhibition of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099014", "l": "neuronal dense core vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000960", "l": "regulation of cellooligosaccharide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072709", "l": "cellular response to sorbitol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0046352", "l": "disaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900327", "l": "regulation of mannotriose transport", "d": ["Any process that modulates the frequency, rate or extent of mannotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035708", "l": "interleukin-4-dependent isotype switching to IgE isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4)."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0009690", "l": "cytokinin metabolic process", "d": ["The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072049", "l": "comma-shaped body morphogenesis", "d": ["The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034453", "l": "microtubule anchoring", "d": ["Any process in which a microtubule is maintained in a specific location in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034242", "l": "negative regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006114", "l": "glycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0015772", "l": "oligosaccharide transport", "d": ["The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903233", "l": "regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099644", "l": "protein localization to presynaptic membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901212", "l": "positive regulation of cardiac chamber formation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac chamber formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904400", "l": "response to Thyroid stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0075071", "l": "symbiont-mediated perturbation of host autophagy", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048481", "l": "plant ovule development", "d": ["The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.577164708155649", "identifiers": [{"i": "GO:0002683", "l": "negative regulation of immune system process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071330", "l": "cellular response to trehalose-6-phosphate stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905716", "l": "negative regulation of cornification", "d": ["Any process that stops, prevents or reduces the 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(e.g. mannitol, sorbitol) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120007", "l": "negative regulation of glutamatergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032819", "l": "positive regulation of natural killer cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902306", "l": "negative regulation of sodium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070162", "l": "adiponectin secretion", "d": ["The regulated release of adiponectin, a protein hormone, by adipose tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048299", "l": "regulation of isotype switching to IgD isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060140", "l": "modulation by virus of syncytium formation via plasma membrane fusion", "d": ["The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001156", "l": "regulation of proline catabolic process to glutamate", "d": ["Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014850", "l": "response to muscle activity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0060235", "l": "lens induction in camera-type eye", "d": ["Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009176", "l": "pyrimidine deoxyribonucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046739", "l": "transport of virus in multicellular host", "d": ["The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090190", "l": "positive regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905430", "l": "cellular response to glycine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904324", "l": "negative regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039705", "l": "viral translational readthrough", "d": ["The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035994", "l": "response to muscle stretch", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036341", "l": "chitin-based cuticle sclerotization by protein cross-linking", "d": ["The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032197", "l": "retrotransposition", "d": ["A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035508", "l": "positive regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160060", "l": "sleep homeostasis", "d": ["A homeostatic process in which the drive for sleep increases sleep propensity with prolonged wakefulness."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002314", "l": "germinal center B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010626", "l": "negative regulation of Schwann cell proliferation", "d": ["Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048713", "l": "regulation of oligodendrocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.450199040858031", "identifiers": [{"i": "GO:0048523", "l": "negative regulation of cellular process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009246", "l": "enterobacterial common antigen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0030221", "l": "basophil differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900161", "l": "regulation of phospholipid scramblase activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipid scramblase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902212", "l": "negative regulation of prolactin signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060514", "l": "prostate induction", "d": ["The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035608", "l": "protein deglutamylation", "d": ["The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000947", "l": "positive regulation of amylopectin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006277", "l": "DNA amplification", "d": ["The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046484", "l": "oxazole or thiazole metabolic process", "d": ["The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903871", "l": "DNA recombinase mediator complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901429", "l": "negative regulation of syringal lignin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032097", "l": "positive regulation of response to food", "d": ["Any process that activates, maintains, or increases the rate of a response to a food stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010373", "l": "negative regulation of gibberellin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090414", "l": "molybdate ion export from vacuole", "d": ["The directed movement of molybdate ions out of the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090057", "l": "root radial pattern formation", "d": ["The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904544", "l": "positive regulation of free ubiquitin chain polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033029", "l": "regulation of neutrophil apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060579", "l": "ventral spinal cord interneuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903520", "l": "negative regulation of mammary gland involution", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904781", "l": "positive regulation of protein localization to centrosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090521", "l": "podocyte cell migration", "d": ["The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071710", "l": "membrane macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019489", "l": "methylgallate metabolic process", "d": ["The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090408", "l": "phloem nitrate loading", "d": ["The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032678", "l": "regulation of interleukin-9 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-9 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021645", "l": "vagus nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0071709", "l": "membrane assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045848", "l": "positive regulation of nitrogen utilization", "d": ["Any process that activates or increases the frequency, rate or extent of nitrogen utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141043", "l": "evasion of host innate immune recognition", "d": ["A process by which a symbiont avoids recognition by host's innate immune response by altering a conserved molecule recognized by the host's cell surface and intracellular innate immune receptors, including Toll-like receptors, and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043932", "l": "ossification involved in bone remodeling", "d": ["The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0021697", "l": "cerebellar cortex formation", "d": ["The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051451", "l": "myoblast migration", "d": ["The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071700", "l": "olfactory placode maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000232", "l": "regulation of rRNA processing", "d": ["Any process that modulates the frequency, rate or extent of rRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006055", "l": "CMP-N-acetylneuraminate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010029", "l": "regulation of seed germination", "d": ["Any process that modulates the frequency, rate or extent of seed germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036296", "l": "response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090728", "l": "negative regulation of brood size", "d": ["Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006562", "l": "proline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002613", "l": "regulation of monocyte antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060442", "l": "branching involved in prostate gland morphogenesis", "d": ["The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140471", "l": "positive regulation of transepithelial migration of symbiont in host", "d": ["Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900801", "l": "cspyrone B1 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cspyrone B1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021763", "l": "subthalamic nucleus development", "d": ["The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000684", "l": "negative regulation of cellular response to X-ray", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904510", "l": "positive regulation of protein localization to basolateral plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002599", "l": "negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060040", "l": "retinal bipolar neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045828", "l": "positive regulation of isoprenoid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140429", "l": "positive regulation of mitotic sister chromatid biorientation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900564", "l": "chanoclavine-I metabolic process", "d": ["The chemical reactions and pathways involving chanoclavine-I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016058", "l": "maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling", "d": ["Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002209", "l": "behavioral defense response", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat to that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000162", "l": "negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061528", "l": "aspartate secretion", "d": ["The regulated release of aspartate by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009694", "l": "jasmonic acid metabolic process", "d": ["The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045965", "l": "negative regulation of ecdysteroid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903593", "l": "regulation of histamine secretion by mast cell", "d": ["Any process that modulates the frequency, rate or extent of histamine secretion by mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042918", "l": "alkanesulfonate transport", "d": ["The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070454", "l": "negative regulation of heme biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097698", "l": "telomere maintenance via base-excision repair", "d": ["A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0099504", "l": "synaptic vesicle cycle", "d": ["A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008078", "l": "mesodermal cell migration", "d": ["The orderly movement of mesodermal cells from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010771", "l": "negative regulation of cell morphogenesis", "d": ["Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904626", "l": "positive regulation of glycine secretion, neurotransmission", "d": ["Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904272", "l": "L-tryptophan import across plasma membrane", "d": ["The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0072376", "l": "protein activation cascade", "d": ["A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0002922", "l": "positive regulation of humoral immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a humoral immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045611", "l": "negative regulation of hemocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0070592", "l": "cell wall polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007474", "l": "imaginal disc-derived wing vein specification", "d": ["The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010093", "l": "specification of floral organ identity", "d": ["The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904674", "l": "positive regulation of somatic stem cell population maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015953", "l": "pyrimidine nucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002001", "l": "renin secretion into blood stream", "d": ["The regulated release of renin into the blood stream by juxtoglomerular cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060300", "l": "regulation of cytokine activity", "d": ["Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033252", "l": "regulation of beta-lactamase activity", "d": ["Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060934", "l": "His-Purkinje system cell fate commitment", "d": ["The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060790", "l": "tooth placode formation", "d": ["The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901583", "l": "tetrapeptide import across plasma membrane", "d": ["The directed movement of a tetrapeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042714", "l": "dosage compensation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034243", "l": "regulation of transcription elongation by RNA polymerase II", "d": ["Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061179", "l": "negative regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035635", "l": "entry of bacterium into host cell", "d": ["The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:1902679", "l": "negative regulation of RNA biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.621042396951871", "identifiers": [{"i": "GO:0097254", "l": "renal tubular secretion", "d": ["The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036036", "l": "cardiac neural crest cell delamination", "d": ["The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075203", "l": "positive regulation of penetration hypha formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097498", "l": "endothelial tube lumen extension", "d": ["Any endothelial tube morphogenesis process by which the tube is increased in length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072119", "l": "head kidney structural organization", "d": ["The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000029", "l": "regulation of proanthocyanidin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090107", "l": "regulation of high-density lipoprotein particle assembly", "d": ["Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150179", "l": "positive regulation of phosphatidylserine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019920", "l": "peptidyl-1-thioglycine biosynthetic process, internal", "d": ["The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046201", "l": "cyanate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072553", "l": "terminal button organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990611", "l": "regulation of cytoplasmic translational initiation in response to stress", "d": ["Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048326", "l": "positive regulation of axial mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060744", "l": "mammary gland branching involved in thelarche", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904627", "l": "response to phorbol 13-acetate 12-myristate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035160", "l": "maintenance of epithelial integrity, open tracheal system", "d": ["Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903648", "l": "positive regulation of chlorophyll catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019064", "l": "fusion of virus membrane with host plasma membrane", "d": ["Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061699", "l": "peptidyl-lysine deglutarylation", "d": ["The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010615", "l": "positive regulation of cardiac muscle adaptation", "d": ["Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015817", "l": "histidine transport", "d": ["The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070609", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051893", "l": "regulation of focal adhesion assembly", "d": ["Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0042435", "l": "indole-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.036537793402566", "identifiers": [{"i": "GO:0098660", "l": "inorganic ion transmembrane transport", "d": ["The process in which an inorganic ion is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0022028", "l": "tangential migration from the subventricular zone to the olfactory bulb", "d": ["The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060832", "l": "oocyte animal/vegetal axis specification", "d": ["The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032722", "l": "positive regulation of chemokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of chemokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0000272", "l": "polysaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072167", "l": "specification of mesonephric tubule identity", "d": ["The process in which the tubules of the mesonephros acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905693", "l": "regulation of phosphatidic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0061241", "l": "mesonephric nephron epithelium development", "d": ["The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045895", "l": "positive regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0000266", "l": "mitochondrial fission", "d": ["The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0061726", "l": "mitochondrion disassembly", "d": ["The disaggregation of a mitochondrion into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090640", "l": "phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine", "d": ["The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0050802", "l": "circadian sleep/wake cycle, sleep", "d": ["The part of the circadian sleep/wake cycle where the organism is asleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085020", "l": "protein K6-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900080", "l": "positive regulation of arginine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0055078", "l": "sodium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007297", "l": "follicle cell of egg chamber migration", "d": ["The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044873", "l": "lipoprotein localization to membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010133", "l": "proline catabolic process to glutamate", "d": ["The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035459", "l": "vesicle cargo loading", "d": ["The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009970", "l": "cellular response to sulfate starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001262", "l": "positive regulation of semaphorin-plexin signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000231", "l": "positive regulation of pancreatic stellate cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080166", "l": "stomium development", "d": ["The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070395", "l": "lipoteichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034172", "l": "negative regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0060538", "l": "skeletal muscle organ development", "d": ["The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042850", "l": "L-sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0071453", "l": "cellular response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.968527344256771", "identifiers": [{"i": "GO:0160043", "l": "catecholamine secretion, neurotransmission", "d": ["The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003343", "l": "septum transversum development", "d": ["The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903401", "l": "L-lysine transmembrane transport", "d": ["The directed movement of L-lysine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072573", "l": "tolerance induction to lipopolysaccharide", "d": ["Tolerance induction directed at lipopolysaccharide antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039664", "l": "lysis of host organelle involved in viral entry into host cell", "d": ["The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150031", "l": "regulation of protein localization to lysosome", "d": ["Any process that modulates the frequency, rate or extent of protein localization to lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905513", "l": "negative regulation of short-term synaptic potentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905082", "l": "regulation of mitochondrial translational elongation", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042785", "l": "evasion of host immune response via modulation of host cytokine network", "d": ["Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007086", "l": "vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly", "d": ["The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015972", "l": "guanosine pentaphosphate metabolic process", "d": ["The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021970", "l": "corticospinal neuron axon guidance through the basilar pons", "d": ["The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001143", "l": "N-methylnicotinate transport", "d": ["The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0006271", "l": "DNA strand elongation involved in DNA replication", "d": ["The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030026", "l": "intracellular manganese ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of manganese ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035053", "l": "dorsal vessel heart proper cell fate commitment", "d": ["The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010192", "l": "mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140042", "l": "lipid droplet formation", "d": ["A process that results in the assembly, arrangement of constituent parts of a lipid droplet."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090017", "l": "anterior neural plate formation", "d": ["The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0090592", "l": "DNA synthesis involved in DNA replication", "d": ["Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903598", "l": "positive regulation of gap junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of gap junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048251", "l": "elastic fiber assembly", "d": ["Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009133", "l": "nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0032954", "l": "regulation of cytokinetic process", "d": ["Any process that modulates the frequency, rate or extent of a cytokinetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:1901503", "l": "ether biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ether."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905171", "l": "positive regulation of protein localization to phagocytic vesicle", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:2000831", "l": "regulation of steroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of steroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061142", "l": "mesothelial-mesenchymal cell signaling involved in early lung development", "d": ["Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905614", "l": "negative regulation of developmental vegetative growth", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071662", "l": "negative regulation of granzyme B production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062212", "l": "regulation of mitotic DNA replication initiation from early origin", "d": ["Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035393", "l": "chemokine (C-X-C motif) ligand 9 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905297", "l": "positive regulation of neural crest cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.084586243466561", "identifiers": [{"i": "GO:0007267", "l": "cell-cell signaling", "d": ["Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002478", "l": "antigen processing and presentation of exogenous peptide antigen", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006742", "l": "NADP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043276", "l": "anoikis", "d": ["Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990489", "l": "anaerobic pectin catabolic process", "d": ["The chemical reactions and pathways resulting in the 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"86.236661114203869", "identifiers": [{"i": "GO:0045734", "l": "regulation of acetate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033609", "l": "oxalate metabolic process", "d": ["The chemical reactions and pathways involving oxalate, the organic acid ethanedioate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110061", "l": "regulation of angiotensin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904784", "l": "NLRP1 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000538", "l": "positive regulation of B cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of B cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001130", "l": "methane biosynthetic process from trimethylamine", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016105", "l": "triterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070155", "l": "mitochondrial methionyl-tRNA aminoacylation", "d": ["The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018063", "l": "cytochrome c-heme linkage", "d": ["The linkage of cytochromes and other heme proteins to heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062175", "l": "brexanolone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of brexanolone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061885", "l": "positive regulation of mini excitatory postsynaptic potential", "d": ["Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051013", "l": "microtubule severing", "d": ["The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045662", "l": "negative regulation of myoblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. 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The colon is that part of the large intestine that connects the small intestine to the rectum."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060264", "l": "regulation of respiratory burst involved in inflammatory response", "d": ["Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010937", "l": "regulation of cytoplasmic microtubule depolymerization", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044544", "l": "envenomation resulting in plasminogen activation in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0001979", "l": "regulation of systemic arterial blood pressure by chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902902", "l": "negative regulation of autophagosome assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010809", "l": "negative regulation of synaptic vesicle priming", "d": ["Any process that decreases the frequency, rate or extent of synaptic vesicle priming. 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It can cause local irritation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990809", "l": "endoplasmic reticulum tubular network membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021698", "l": "cerebellar cortex structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0070253", "l": "somatostatin secretion", "d": ["The regulated release of somatostatin from secretory granules in the D cells of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030974", "l": "thiamine pyrophosphate transmembrane transport", "d": ["The process in which thiamine pyrophosphate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0052805", "l": "imidazole-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901250", "l": "negative regulation of lung goblet cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015735", "l": "uronic acid transmembrane transport", "d": ["The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000761", "l": "conjugant formation", "d": ["During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001543", "l": "ovarian follicle rupture", "d": ["Disruption of theca cell layer releasing follicular fluid and/or the oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072639", "l": "interleukin-33 production", "d": ["The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900498", "l": "negative regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036084", "l": "GDP-fucose import into endoplasmic reticulum lumen", "d": ["The directed movement of GDP-fucose into the endoplasmic reticulum lumen. 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The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035046", "l": "pronuclear migration", "d": ["The directed movement of the male and female pronuclei towards each other prior to their fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120059", "l": "negative regulation of small intestinal transit", "d": ["Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010878", "l": "cholesterol storage", "d": ["The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0031943", "l": "regulation of glucocorticoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010955", "l": "negative regulation of protein processing", "d": ["Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000453", "l": "negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902181", "l": "verruculogen biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of verruculogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900360", "l": "regulation of pentasaccharide transport", "d": ["Any process that modulates the frequency, rate or extent of pentasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0060216", "l": "definitive hemopoiesis", "d": ["A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061425", "l": "positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042473", "l": "outer ear morphogenesis", "d": ["The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090314", "l": "positive regulation of protein targeting to membrane", "d": ["Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010409", "l": "extensin metabolic process", "d": ["The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009735", "l": "response to cytokinin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904365", "l": "regulation of chemokinesis", "d": ["Any process that modulates the frequency, rate or extent of chemokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0048925", "l": "lateral line system development", "d": ["The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. 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The lateral line system develops from cranial ectodermal placodes situated between the eye and ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002270", "l": "plasmacytoid dendritic cell activation", "d": ["A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070813", "l": "hydrogen sulfide metabolic process", "d": ["The chemical reactions and pathways involving hydrogen sulfide, H2S."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090289", "l": "regulation of osteoclast proliferation", "d": ["Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071464", "l": "cellular response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). 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Muramyl dipeptide is derived from peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018924", "l": "mandelate metabolic process", "d": ["The chemical reactions and pathways involving mandelate, the anion of mandelic acid. 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This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009802", "l": "cinnamic acid ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140821", "l": "UDP-beta-L-arabinofuranose import into Golgi lumen", "d": ["The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014028", "l": "notochord formation", "d": ["The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042574", "l": "retinal metabolic process", "d": ["The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051001", "l": "negative regulation of nitric-oxide synthase activity", "d": ["Any process that stops or reduces the activity of the enzyme nitric-oxide synthase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031119", "l": "tRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in a tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061248", "l": "mesonephric glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. 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This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040005", "l": "chitin-based cuticle attachment to epithelium", "d": ["Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051259", "l": "protein complex oligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010966", "l": "regulation of phosphate transport", "d": ["Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036274", "l": "response to lapatinib", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033308", "l": "hydroxyectoine transport", "d": ["The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002311", "l": "gamma-delta T cell proliferation involved in immune response", "d": ["The expansion of a gamma-delta T cell 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"biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034394", "l": "protein localization to cell surface", "d": ["A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1990735", "l": "gamma-tubulin complex localization to mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901095", "l": "positive regulation of protein homotetramerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein homotetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072191", "l": "ureter smooth muscle 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"biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060836", "l": "lymphatic endothelial cell differentiation", "d": ["The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.422285095499703", "identifiers": [{"i": "GO:0034330", "l": "cell junction organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0097529", "l": "myeloid leukocyte migration", "d": ["The movement of a myeloid leukocyte within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052704", "l": "ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide", "d": ["The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035983", "l": "response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035741", "l": "activated CD4-positive, alpha-beta T cell proliferation", "d": ["The expansion of an activated CD4-positive, alpha-beta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044627", "l": "modulation of complement activation, classical pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903980", "l": "positive regulation of microglial cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032702", "l": "negative regulation of interleukin-19 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0007549", "l": "dosage compensation", "d": ["Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904049", "l": "negative regulation of spontaneous neurotransmitter secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051369", "l": "peptidyl-threonine decanoylation", "d": ["The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150173", "l": "positive regulation of phosphatidylcholine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900045", "l": "negative regulation of protein K63-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1901021", "l": "positive regulation of calcium ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061017", "l": "hepatoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904614", "l": "response to biphenyl", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046548", "l": "retinal rod cell development", "d": ["Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002943", "l": "tRNA dihydrouridine synthesis", "d": ["The process whereby a uridine in a transfer RNA is converted to dihydrouridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0010951", "l": "negative regulation of endopeptidase activity", "d": ["Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002432", "l": "granuloma formation", "d": ["The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036350", "l": "mannose-specific flocculation", "d": ["The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002814", "l": "negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048347", "l": "negative regulation of paraxial mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060808", "l": "positive regulation of mesodermal to mesenchymal transition involved in gastrulation", "d": ["Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009637", "l": "response to blue light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000830", "l": "positive regulation of parathyroid hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021633", "l": "optic nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097066", "l": "response to thyroid hormone", "d": ["A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045707", "l": "regulation of adult salivary gland boundary specification", "d": ["Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046103", "l": "inosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071835", "l": "mating pheromone secretion involved in regulation of conjugation with cellular fusion", "d": ["The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016062", "l": "adaptation of rhodopsin mediated signaling", "d": ["The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050731", "l": "positive regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048349", "l": "regulation of paraxial mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071236", "l": "cellular response to antibiotic", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006376", "l": "mRNA splice site recognition", "d": ["Selection of a splice site by components of the assembling spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000951", "l": "regulation of xyloglucan catabolic process", "d": ["Any process that modulates the frequency, rate or extent of xyloglucan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0086002", "l": "cardiac muscle cell action potential involved in contraction", "d": ["An action potential that occurs in a cardiac muscle cell and is involved in its contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031539", "l": "positive regulation of anthocyanin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050739", "l": "peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium", "d": ["The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904011", "l": "cellular response to Aroclor 1254", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900728", "l": "cardiac neural crest cell delamination involved in outflow tract morphogenesis", "d": ["Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902892", "l": "positive regulation of root hair elongation", "d": ["Any process that activates or increases the frequency, rate or extent of root hair elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1905710", "l": "positive regulation of membrane permeability", "d": ["Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060377", "l": "negative regulation of mast cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002354", "l": "central B cell negative selection", "d": ["Any process leading to negative selection of B cells in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902104", "l": "positive regulation of metaphase/anaphase transition of meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018968", "l": "tetrahydrofuran metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045916", "l": "negative regulation of complement activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090462", "l": "intracellular ornithine homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019521", "l": "D-gluconate metabolic process", "d": ["The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052003", "l": "symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway", "d": ["A process in which a virus interferes with, inhibits or disrupts a host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097242", "l": "amyloid-beta clearance", "d": ["The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903243", "l": "negative regulation of cardiac muscle hypertrophy in response to stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.14738226640344", "identifiers": [{"i": "GO:0002682", "l": "regulation of immune system process", "d": ["Any process that modulates the frequency, rate, or extent of an immune system process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048834", "l": "specification of petal number", "d": ["Any process that modulates the number of petals formed in a flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1901077", "l": "regulation of relaxation of muscle", "d": ["Any process that modulates the frequency, rate or extent of relaxation of muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019254", "l": "carnitine metabolic process, CoA-linked", "d": ["The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072313", "l": "metanephric glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904255", "l": "negative regulation of iron ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903500", "l": "negative regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002176", "l": "male germ cell proliferation", "d": ["The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0071219", "l": "cellular response to molecule of bacterial origin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021643", "l": "vagus nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902970", "l": "premeiotic DNA replication DNA duplex unwinding", "d": ["Any DNA duplex unwinding involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019287", "l": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001814", "l": "negative regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.45299868619928", "identifiers": [{"i": "GO:0030099", "l": "myeloid cell differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061251", "l": "mesonephric glomerular epithelial cell development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901946", "l": "miltiradiene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of miltiradiene."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0018991", "l": "egg-laying behavior", "d": ["A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904101", "l": "response to acadesine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901403", "l": "positive regulation of tetrapyrrole metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000075", "l": "negative regulation of cytokinesis, site selection", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031945", "l": "positive regulation of glucocorticoid metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061366", "l": "behavioral response to chemical pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033602", "l": "negative regulation of dopamine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900103", "l": "positive regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000418", "l": "positive regulation of eosinophil migration", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002783", "l": "antifungal peptide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antifungal peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034177", "l": "positive regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042983", "l": "amyloid precursor protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900845", "l": "positive regulation of monodictyphenone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071477", "l": "cellular hypotonic salinity response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000513", "l": "positive regulation of granzyme A production", "d": ["Any process that activates or increases the frequency, rate or extent of granzyme A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904534", "l": "negative regulation of telomeric loop disassembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035913", "l": "ventral aorta morphogenesis", "d": ["The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071865", "l": "regulation of apoptotic process in bone marrow cell", "d": ["Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022023", "l": "radial glial cell fate commitment in forebrain", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106064", "l": "regulation of cobalamin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0007625", "l": "grooming behavior", "d": ["The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903232", "l": "melanosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030920", "l": "peptidyl-serine acetylation", "d": ["The acetylation of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0046374", "l": "teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990938", "l": "peptidyl-aspartic acid autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098725", "l": "symmetric cell division", "d": ["Cell division in which both daughter cells are of the same type."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042688", "l": "crystal cell differentiation", "d": ["The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033120", "l": "positive regulation of RNA splicing", "d": ["Any process that activates or increases the frequency, rate or extent of RNA splicing."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051205", "l": "protein insertion into membrane", "d": ["The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006910", "l": "phagocytosis, recognition", "d": ["The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019442", "l": "tryptophan catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021664", "l": "rhombomere 5 morphogenesis", "d": ["The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044357", "l": "regulation of rRNA stability", "d": ["Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034201", "l": "response to oleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007481", "l": "haltere disc morphogenesis", "d": ["The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039602", "l": "suppression by virus of host transcription initiation from RNA polymerase II promoter", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051140", "l": "regulation of NK T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of natural killer T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901325", "l": "response to antimycin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904710", "l": "positive regulation of granulosa cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900098", "l": "regulation of plasma cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of plasma cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033376", "l": "establishment of protein localization to T cell secretory granule", "d": ["The directed movement of a protein to a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045625", "l": "regulation of T-helper 1 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052800", "l": "bicyclic nitroimidazole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060997", "l": "dendritic spine morphogenesis", "d": ["The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051759", "l": "sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation", "d": ["The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072193", "l": "ureter smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.576180114155946", "identifiers": [{"i": "GO:0006914", "l": "autophagy", "d": ["The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061971", "l": "replacement bone morphogenesis", "d": ["The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000452", "l": "snoRNA guided rRNA 2'-O-methylation", "d": ["The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097430", "l": "copper ion import across prospore membrane", "d": ["The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006882", "l": "intracellular zinc ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of zinc ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019349", "l": "ribitol metabolic process", "d": ["The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036085", "l": "GDP-fucose import into Golgi lumen", "d": ["The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035845", "l": "photoreceptor cell outer segment organization", "d": ["A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014884", "l": "detection of muscle inactivity involved in regulation of muscle adaptation", "d": ["The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002482", "l": "antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008058", "l": "ocellus pigment granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002485", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904990", "l": "regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003234", "l": "bulbus arteriosus formation", "d": ["The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990859", "l": "cellular response to endothelin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010430", "l": "fatty acid omega-oxidation", "d": ["A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071325", "l": "cellular response to mannitol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035760", "l": "cytoplasmic polyadenylation-dependent rRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071206", "l": "establishment of protein localization to juxtaparanode region of axon", "d": ["The directed movement of a protein to the juxtaparanode region of an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009906", "l": "response to photoperiod, blue light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905526", "l": "regulation of Golgi lumen acidification", "d": ["Any process that modulates the frequency, rate or extent of Golgi lumen acidification."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.412000789628095", "identifiers": [{"i": "GO:0044068", "l": "modulation by symbiont of host cellular process", "d": ["Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010004", "l": "gastrulation involving germ band extension", "d": ["A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051000", "l": "positive regulation of nitric-oxide synthase activity", "d": ["Any process that activates or increases the activity of the enzyme nitric-oxide synthase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042821", "l": "pyridoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904036", "l": "negative regulation of epithelial cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035768", "l": "endothelial cell chemotaxis to fibroblast growth factor", "d": ["The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007545", "l": "processes downstream of sex determination signal", "d": ["The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902312", "l": "negative regulation of copper ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060315", "l": "negative regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010572", "l": "positive regulation of platelet activation", "d": ["Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003299", "l": "muscle hypertrophy in response to stress", "d": ["The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904126", "l": "convergent extension involved in notochord morphogenesis", "d": ["Any convergent extension that is involved in notochord morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061706", "l": "glycolytic process from sucrose through glucose and fructose", "d": ["The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.245311748130447", "identifiers": [{"i": "GO:0031669", "l": "cellular response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061477", "l": "response to aromatase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071267", "l": "L-methionine salvage", "d": ["Any process that generates L-methionine from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002940", "l": "tRNA N2-guanine methylation", "d": ["The process whereby a guanine in a tRNA is methylated at the N2 position of guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090122", "l": "cholesterol ester hydrolysis involved in cholesterol transport", "d": ["The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030837", "l": "negative regulation of actin filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060207", "l": "diestrus", "d": ["The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0099124", "l": "axonal dopamine secretion", "d": ["The regulated release of dopamine from an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904262", "l": "negative regulation of TORC1 signaling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033499", "l": "galactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006069", "l": "ethanol oxidation", "d": ["An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904473", "l": "response to L-dopa", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001742", "l": "oenocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0006446", "l": "regulation of translational initiation", "d": ["Any process that modulates the frequency, rate or extent of translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090233", "l": "negative regulation of spindle checkpoint", "d": ["Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033088", "l": "negative regulation of immature T cell proliferation in thymus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000458", "l": "endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "d": ["Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905643", "l": "positive regulation of DNA methylation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0090605", "l": "submerged biofilm formation", "d": ["A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990045", "l": "sclerotium development", "d": ["The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014813", "l": "skeletal muscle satellite cell commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904514", "l": "positive regulation of initiation of premeiotic DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035713", "l": "response to nitrogen dioxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015973", "l": "guanosine pentaphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006660", "l": "phosphatidylserine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0072402", "l": "response to DNA integrity checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042371", "l": "vitamin K biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000244", "l": "spliceosomal tri-snRNP complex assembly", "d": ["The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051038", "l": "negative regulation of transcription involved in meiotic cell cycle", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901843", "l": "positive regulation of high voltage-gated calcium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000271", "l": "positive regulation of fibroblast apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061286", "l": "mesonephric capsule morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903407", "l": "negative regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060932", "l": "His-Purkinje system cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.256959333395912", "identifiers": [{"i": "GO:0051239", "l": "regulation of multicellular organismal process", "d": ["Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905561", "l": "positive regulation of kinetochore assembly", "d": ["Any process that activates or increases the frequency, rate or extent of kinetochore assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001059", "l": "transcription by RNA polymerase IV", "d": ["The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900552", "l": "asperfuranone metabolic process", "d": ["The chemical reactions and pathways involving asperfuranone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001551", "l": "ovarian follicle endowment", "d": ["Association of oocytes with supporting epithelial granulosa cells to form primordial follicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001126", "l": "positive regulation of translational frameshifting", "d": ["Any process that activates or increases the frequency, rate or extent of translational frameshifting."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046782", "l": "regulation of viral transcription", "d": ["Any process that modulates the frequency, rate or extent of the transcription of the viral genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0016118", "l": "carotenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902866", "l": "regulation of retina development in camera-type eye", "d": ["Any process that modulates the frequency, rate or extent of retina development in camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002792", "l": "negative regulation of peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.859901931638547", "identifiers": [{"i": "GO:0005976", "l": "polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0010517", "l": "regulation of phospholipase activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051123", "l": "RNA polymerase II preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050862", "l": "positive regulation of T cell receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903726", "l": "negative regulation of phospholipid metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046308", "l": "Z-phenylacetaldoxime catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160022", "l": "apocrine secretion", "d": ["The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032340", "l": "positive regulation of inhibin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.240937671532407", "identifiers": [{"i": "GO:0044380", "l": "protein localization to cytoskeleton", "d": ["A process in which a protein is transported to, or maintained in, a location within the cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002542", "l": "Factor XII activation", "d": ["Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060702", "l": "negative regulation of endoribonuclease activity", "d": ["Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002082", "l": "regulation of oxidative phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900136", "l": "regulation of chemokine activity", "d": ["Any process that modulates the frequency, rate or extent of chemokine activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1905898", "l": "positive regulation of response to endoplasmic reticulum stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060908", "l": "plasmid copy number maintenance", "d": ["The maintenance of the number of copies of extrachromosomal plasmid DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046689", "l": "response to mercury ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085016", "l": "dormancy exit of symbiont in host", "d": ["Exit from dormant state, also known as resuscitation, of the symbiont within the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0016578", "l": "histone deubiquitination", "d": ["The modification of histones by removal of ubiquitin groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070343", "l": "white fat cell proliferation", "d": ["The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0010657", "l": "muscle cell apoptotic process", "d": ["A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900337", "l": "negative regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070650", "l": "actin filament bundle distribution", "d": ["Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900703", "l": "positive regulation of orcinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900212", "l": "negative regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0022617", "l": "extracellular matrix disassembly", "d": ["A process that results in the breakdown of the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070269", "l": "pyroptosis", "d": ["A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0052703", "l": "cellular modified histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903444", "l": "negative regulation of brown fat cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062088", "l": "negative regulation of vein smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of vein smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0018206", "l": "peptidyl-methionine modification", "d": ["The modification of peptidyl-methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902291", "l": "cell cycle DNA replication DNA ligation", "d": ["Any DNA ligation that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0086013", "l": "membrane repolarization during cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905560", "l": "negative regulation of kinetochore assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097737", "l": "acquisition of mycelium reproductive competence", "d": ["A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045339", "l": "farnesyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090232", "l": "positive regulation of spindle checkpoint", "d": ["Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0016122", "l": "xanthophyll metabolic process", "d": ["The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905504", "l": "negative regulation of motile cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000694", "l": "regulation of phragmoplast microtubule organization", "d": ["Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.929933841797123", "identifiers": [{"i": "GO:0061640", "l": "cytoskeleton-dependent cytokinesis", "d": ["A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904908", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072342", "l": "response to anion stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902884", "l": "positive regulation of response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002910", "l": "positive regulation of peripheral B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033339", "l": "pectoral fin development", "d": ["The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035309", "l": "wing and notum subfield formation", "d": ["The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0052020", "l": "modification by symbiont of host cell wall", "d": ["The process in which an organism effects a change in the structure or function of the host cell wall. 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The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043616", "l": "keratinocyte proliferation", "d": ["The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0097035", "l": "regulation of membrane lipid distribution", "d": ["Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048836", "l": "specification of increased petal number", "d": ["Any process that increases the number of petals produced in a developing flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061462", "l": "protein localization to lysosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903622", "l": "regulation of RNA polymerase III activity", "d": ["Any process that modulates the frequency, rate or extent of RNA polymerase III activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0030111", "l": "regulation of Wnt signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000473", "l": "positive regulation of hematopoietic stem cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044269", "l": "glycerol ether catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905371", "l": "ceramide phosphoethanolamine metabolic process", "d": ["The chemical reactions and pathways involving ceramide phosphoethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061031", "l": "endodermal digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071408", "l": "cellular response to cycloalkane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032447", "l": "protein urmylation", "d": ["Covalent attachment of the ubiquitin-like protein URM1 to another protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902723", "l": "negative regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2001222", "l": "regulation of neuron migration", "d": ["Any process that modulates the frequency, rate or extent of neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050989", "l": "N-terminal protein amino acid carboxylation", "d": ["The carboxylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904911", "l": "negative regulation of establishment of RNA localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010956", "l": "negative regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075343", "l": "modulation by symbiont of abscisic acid levels in host", "d": ["The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046776", "l": "suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061001", "l": "regulation of dendritic spine morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036306", "l": "embryonic heart tube elongation", "d": ["The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0045930", "l": "negative regulation of mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0003179", "l": "heart valve morphogenesis", "d": ["The process in which the structure of a heart valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0048882", "l": "lateral line development", "d": ["The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010683", "l": "tricyclic triterpenoid metabolic process", "d": ["The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052710", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0032642", "l": "regulation of chemokine production", "d": ["Any process that modulates the frequency, rate, or extent of chemokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905233", "l": "response to codeine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072750", "l": "cellular response to leptomycin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0006560", "l": "proline metabolic process", "d": ["The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900326", "l": "positive regulation of maltotriulose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltotriulose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002013", "l": "detection of carbon dioxide by vasomotor center", "d": ["The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0098780", "l": "response to mitochondrial depolarisation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060611", "l": "mammary gland fat development", "d": ["The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905524", "l": "negative regulation of protein autoubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0090696", "l": "post-embryonic plant organ development", "d": ["Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006308", "l": "DNA catabolic process", "d": ["The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097323", "l": "B cell adhesion", "d": ["The attachment of a B cell to another cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010446", "l": "response to alkaline pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0016128", "l": "phytosteroid metabolic process", "d": ["The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106396", "l": "regulation of R7 cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of R7 cell fate commitment."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030450", "l": "regulation of complement activation, classical pathway", "d": ["Any process that modulates the frequency, rate or extent of the classical pathway of complement activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900688", "l": "positive regulation of gerfelin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048092", "l": "negative regulation of male pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051770", "l": "positive regulation of nitric-oxide synthase biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901199", "l": "positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress", "d": ["Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021863", "l": "forebrain neuroblast differentiation", "d": ["The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0006639", "l": "acylglycerol metabolic process", "d": ["The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2001228", "l": "regulation of response to gamma radiation", "d": ["Any process that modulates the frequency, rate or extent of response to gamma radiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002930", "l": "trabecular meshwork development", "d": ["The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0042398", "l": "cellular modified amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900926", "l": "regulation of L-threonine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-threonine import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110113", "l": "positive regulation of lipid transporter activity", "d": ["Any process that increases the frequency, rate, or extent of lipid transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018028", "l": "peptidyl-lysine myristoylation", "d": ["The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1903115", "l": "regulation of actin filament-based movement", "d": ["Any process that modulates the frequency, rate or extent of actin filament-based movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075522", "l": "IRES-dependent viral translational initiation", "d": ["Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002283", "l": "neutrophil activation involved in immune response", "d": ["The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071959", "l": "maintenance of mitotic sister chromatid cohesion, arms", "d": ["The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046075", "l": "dTTP metabolic process", "d": ["The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034773", "l": "histone H4-K20 trimethylation", "d": ["The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1902363", "l": "regulation of protein localization to spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032201", "l": "telomere maintenance via semi-conservative replication", "d": ["The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006229", "l": "dUTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090351", "l": "seedling development", "d": ["The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141032", "l": "perturbation by symbiont of host actin cytoskeleton via actin filament reorganization", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080181", "l": "lateral root branching", "d": ["Any process involved in the formation of branches in lateral roots."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051068", "l": "dihydrolipoamide metabolic process", "d": ["The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901871", "l": "ecgonone methyl ester catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060917", "l": "regulation of (1->6)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015976", "l": "carbon utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018900", "l": "dichloromethane metabolic process", "d": ["The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071699", "l": "olfactory placode morphogenesis", "d": ["The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016057", "l": "regulation of membrane potential in photoreceptor cell", "d": ["Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0006282", "l": "regulation of DNA repair", "d": ["Any process that modulates the frequency, rate or extent of DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006507", "l": "GPI anchor release", "d": ["The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033563", "l": "dorsal/ventral axon guidance", "d": ["The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140712", "l": "negative regulation of Frizzled Nuclear Import pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097052", "l": "L-kynurenine metabolic process", "d": ["The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000747", "l": "negative regulation of defecation rhythm", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052151", "l": "positive regulation by symbiont of host apoptotic process", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007479", "l": "leg disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010455", "l": "positive regulation of cell fate commitment", "d": ["Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003182", "l": "coronary sinus valve morphogenesis", "d": ["The process in which the structure of the coronary sinus valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018203", "l": "peptidyl-isoleucine modification", "d": ["The modification of peptidyl-isoleucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003223", "l": "ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.747898232598239", "identifiers": [{"i": "GO:0044419", "l": "biological process involved in interspecies interaction between organisms", "d": ["Any process evolved to enable an interaction with an organism of a different species."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0060042", "l": "retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042780", "l": "tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0001783", "l": "B cell apoptotic process", "d": ["Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018094", "l": "protein polyglycylation", "d": ["The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097392", "l": "chemokine (C-X-C motif) ligand 16 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0033273", "l": "response to vitamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000534", "l": "positive regulation of renal albumin absorption", "d": ["Any process that activates or increases the frequency, rate or extent of renal albumin absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902755", "l": "sulfurated eukaryotic molybdenum cofactor(2-) metabolic process", "d": ["The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0098935", "l": "dendritic transport", "d": ["The directed movement of organelles or molecules along microtubules in dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046960", "l": "sensitization", "d": ["An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090256", "l": "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis", "d": ["Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072230", "l": "metanephric proximal straight tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001033", "l": "negative regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.579038937824933", "identifiers": [{"i": "GO:0030072", "l": "peptide hormone secretion", "d": ["The regulated release of a peptide hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072134", "l": "nephrogenic mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. 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Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120331", "l": "endothelial tube formation", "d": ["The developmental process pertaining to the initial formation of an endothelial tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901004", "l": "ubiquinone-6 metabolic process", "d": ["The chemical reactions and pathways involving ubiquinone-6. 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A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019544", "l": "arginine catabolic process to glutamate", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900639", "l": "positive regulation of asperfuranone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042997", "l": "negative regulation of Golgi to plasma membrane protein transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036228", "l": "protein localization to nuclear inner membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071244", "l": "cellular response to carbon dioxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001865", "l": "NK T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a NK T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0048259", "l": "regulation of receptor-mediated endocytosis", "d": ["Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007370", "l": "ventral furrow formation", "d": ["Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900647", "l": "negative regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046828", "l": "regulation of RNA import into nucleus", "d": ["Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.925062519739775", "identifiers": [{"i": "GO:0030029", "l": "actin filament-based process", "d": ["Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048900", "l": "anterior lateral line neuromast primordium migration", "d": ["The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002158", "l": "osteoclast proliferation", "d": ["The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0048242", "l": "epinephrine secretion", "d": ["The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:1905954", "l": "positive regulation of lipid localization", "d": ["Any process that activates or increases the frequency, rate or extent of lipid localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010026", "l": "trichome differentiation", "d": ["The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050929", "l": "induction of negative chemotaxis", "d": ["Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903461", "l": "Okazaki fragment processing involved in mitotic DNA replication", "d": ["Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.779589259036598", "identifiers": [{"i": "GO:0016054", "l": "organic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010931", "l": "macrophage tolerance induction", "d": ["A process involving any mechanism for tolerance induction in macrophages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048033", "l": "heme O metabolic process", "d": ["The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0071375", "l": "cellular response to peptide hormone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072746", "l": "cellular response to tetracycline", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045869", "l": "negative regulation of single stranded viral RNA replication via double stranded DNA intermediate", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0030242", "l": "autophagy of peroxisome", "d": ["The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090378", "l": "seed trichome elongation", "d": ["The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071596", "l": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048497", "l": "maintenance of floral organ identity", "d": ["The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901917", "l": "regulation of exoribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exoribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0031297", "l": "replication fork processing", "d": ["The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900797", "l": "cordyol C metabolic process", "d": ["The chemical reactions and pathways involving cordyol C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000914", "l": "phragmoplast assembly", "d": ["The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033507", "l": "glucosinolate biosynthetic process from phenylalanine", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900493", "l": "positive regulation of [4Fe-4S] cluster assembly", "d": ["Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002625", "l": "regulation of T cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035052", "l": "dorsal vessel aortic cell fate commitment", "d": ["The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140882", "l": "zinc export across plasma membrane", "d": ["The directed movement of zinc ions from a cell, into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905111", "l": "positive regulation of pulmonary blood vessel remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009557", "l": "antipodal cell differentiation", "d": ["The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0098732", "l": "macromolecule deacylation", "d": ["The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904899", "l": "positive regulation of hepatic stellate cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043297", "l": "apical junction assembly", "d": ["The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905127", "l": "negative regulation of axo-dendritic protein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000626", "l": "negative regulation of miRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904692", "l": "positive regulation of type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061626", "l": "pharyngeal arch artery morphogenesis", "d": ["The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901247", "l": "negative regulation of lung ciliated cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072216", "l": "positive regulation of metanephros development", "d": ["Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045613", "l": "regulation of plasmatocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of plasmatocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003249", "l": "cell proliferation involved in heart valve morphogenesis", "d": ["The multiplication or reproduction of cells that contributes to the shaping of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042847", "l": "sorbose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021509", "l": "roof plate formation", "d": ["The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.06015934163878", "identifiers": [{"i": "GO:0099111", "l": "microtubule-based transport", "d": ["A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033133", "l": "positive regulation of glucokinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903964", "l": "monounsaturated fatty acid metabolic process", "d": ["The chemical reactions and pathways involving monounsaturated fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000569", "l": "regulation of T-helper 2 cell activation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 2 cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060470", "l": "positive regulation of cytosolic calcium ion concentration involved in egg activation", "d": ["The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030846", "l": "termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["An RNA polymerase II transcription termination process in which cleavage and polyadenylylation of the mRNA 3' end are coupled to transcription termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0071676", "l": "negative regulation of mononuclear cell migration", "d": ["Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0046794", "l": "transport of virus", "d": ["The directed movement of a virus, or part of a virus, into, out of, or within a host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010091", "l": "trichome branching", "d": ["Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003422", "l": "growth plate cartilage morphogenesis", "d": ["The process in which the anatomical structures of growth plate cartilage are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048375", "l": "negative regulation of lateral mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990764", "l": "myofibroblast contraction", "d": ["The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002288", "l": "NK T cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000952", "l": "aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044536", "l": "envenomation resulting in depletion of circulating fibrinogen in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072597", "l": "maintenance of protein location in chloroplast", "d": ["Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905209", "l": "positive regulation of cardiocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002648", "l": "positive regulation of central tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of central tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045630", "l": "positive regulation of T-helper 2 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009152", "l": "purine ribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015841", "l": "chromaffin granule amine transport", "d": ["The directed movement of amines into, out of or within chromaffin granules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030581", "l": "symbiont intracellular protein transport in host", "d": ["The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003254", "l": "regulation of membrane depolarization", "d": ["Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075503", "l": "fusion of virus membrane with host macropinosome membrane", "d": ["Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031564", "l": "transcription antitermination", "d": ["A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048445", "l": "carpel morphogenesis", "d": ["The process in which the anatomical structures of the carpel are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030590", "l": "first cell cycle pseudocleavage", "d": ["A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901933", "l": "bicyclogermacrene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0071103", "l": "DNA conformation change", "d": ["A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904559", "l": "cellular response to dextromethorphan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006566", "l": "threonine metabolic process", "d": ["The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009304", "l": "tRNA transcription", "d": ["The synthesis of transfer RNA (tRNA) from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080141", "l": "regulation of jasmonic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080052", "l": "response to histidine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033340", "l": "pelvic fin development", "d": ["The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010478", "l": "chlororespiration", "d": ["A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075525", "l": "viral translational termination-reinitiation", "d": ["A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036525", "l": "protein deglycation", "d": ["The removal of a sugar or dicarbonyl from a glycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0061224", "l": "mesonephric glomerulus development", "d": ["The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0006364", "l": "rRNA processing", "d": ["Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097315", "l": "response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033049", "l": "clavulanic acid metabolic process", "d": ["The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000515", "l": "negative regulation of CD4-positive, alpha-beta T cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032380", "l": "regulation of intracellular sterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060117", "l": "auditory receptor cell development", "d": ["The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060928", "l": "atrioventricular node cell development", "d": ["The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075263", "l": "oogonium development", "d": ["The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0008380", "l": "RNA splicing", "d": ["The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051988", "l": "regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090263", "l": "positive regulation of canonical Wnt signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002353", "l": "plasma kallikrein-kinin cascade", "d": ["A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000658", "l": "positive regulation of apolipoprotein binding", "d": ["Any process that activates or increases the frequency, rate or extent of apolipoprotein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0009250", "l": "glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062026", "l": "negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "d": ["Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140874", "l": "paraherquonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002888", "l": "positive regulation of myeloid leukocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0021984", "l": "adenohypophysis development", "d": ["The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905154", "l": "negative regulation of membrane invagination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071807", "l": "replication fork arrest involved in DNA replication termination", "d": ["A replication fork arrest process that contributes to the termination of DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140147", "l": "zinc ion export from vacuole", "d": ["The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043407", "l": "negative regulation of MAP kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904050", "l": "positive regulation of spontaneous neurotransmitter secretion", "d": ["Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901033", "l": "positive regulation of response to reactive oxygen species", "d": ["Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0007556", "l": "regulation of juvenile hormone metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0048915", "l": "posterior lateral line system development", "d": ["The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035125", "l": "embryonic anal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032712", "l": "negative regulation of interleukin-3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901959", "l": "positive regulation of cutin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052036", "l": "suppression by symbiont of host inflammatory response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900592", "l": "violaceol II catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of violaceol II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106148", "l": "4-hydroxyindole-3- carbonyl nitrile biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052081", "l": "perturbation of defense-related host salicylic acid-mediated signal transduction pathway", "d": ["A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021628", "l": "olfactory nerve formation", "d": ["The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905167", "l": "positive regulation of lysosomal protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017187", "l": "peptidyl-glutamic acid carboxylation", "d": ["The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046447", "l": "terpenoid indole alkaloid metabolic process", "d": ["The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902988", "l": "neurofibrillary tangle assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042444", "l": "phenylethylamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0009953", "l": "dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045672", "l": "positive regulation of osteoclast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of osteoclast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014857", "l": "regulation of skeletal muscle cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903782", "l": "regulation of sodium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032290", "l": "peripheral nervous system myelin formation", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046069", "l": "cGMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046300", "l": "2,4-dichlorophenoxyacetic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006408", "l": "snRNA export from nucleus", "d": ["The directed movement of snRNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903539", "l": "protein localization to postsynaptic membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050924", "l": "positive regulation of negative chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905872", "l": "negative regulation of protein localization to cell leading edge", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0048507", "l": "meristem development", "d": ["The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090508", "l": "phenylethylamine biosynthetic process involved in synaptic transmission", "d": ["The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0044114", "l": "development of symbiont in host", "d": ["The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043453", "l": "alkyne biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070121", "l": "Kupffer's vesicle development", "d": ["The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901098", "l": "positive regulation of autophagosome maturation", "d": ["Any process that activates or increases the frequency, rate or extent of autophagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0009409", "l": "response to cold", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905799", "l": "regulation of intraciliary retrograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904796", "l": "regulation of core promoter binding", "d": ["Any process that modulates the frequency, rate or extent of core promoter binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031318", "l": "detection of folic acid", "d": ["The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036182", "l": "asperthecin metabolic process", "d": ["The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.8317879456661", "identifiers": [{"i": "GO:0050801", "l": "monoatomic ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050950", "l": "positive regulation of late stripe melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000880", "l": "positive regulation of dipeptide transport", "d": ["Any process that activates or increases the frequency, rate or extent of dipeptide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904433", "l": "negative regulation of ferrous iron binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.569289279670436", "identifiers": [{"i": "GO:0030855", "l": "epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000863", "l": "positive regulation of estrogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046279", "l": "3,4-dihydroxybenzoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075224", "l": "positive regulation of sporangium germination", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014818", "l": "skeletal muscle satellite cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046416", "l": "D-amino acid metabolic process", "d": ["The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048722", "l": "anterior cibarial plate development", "d": ["The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048840", "l": "otolith development", "d": ["The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900813", "l": "monodictyphenone metabolic process", "d": ["The chemical reactions and pathways involving monodictyphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006780", "l": "uroporphyrinogen III biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uroporphyrinogen III."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002721", "l": "regulation of B cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of B cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900267", "l": "positive regulation of substance P receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of substance P receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051583", "l": "dopamine uptake involved in synaptic transmission", "d": ["The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043639", "l": "benzoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003404", "l": "optic vesicle morphogenesis", "d": ["The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061197", "l": "fungiform papilla morphogenesis", "d": ["The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902654", "l": "aromatic primary alcohol metabolic process", "d": ["The chemical reactions and pathways involving aromatic primary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035067", "l": "negative regulation of histone acetylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990679", "l": "histone H4-K12 deacetylation", "d": ["The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903805", "l": "L-valine import across plasma membrane", "d": ["The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900496", "l": "positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019658", "l": "glucose fermentation to lactate and acetate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044476", "l": "envenomation resulting in negative regulation of low voltage-gated calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905854", "l": "negative regulation of heparan sulfate binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046087", "l": "cytidine metabolic process", "d": ["The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014739", "l": "positive regulation of muscle hyperplasia", "d": ["Any process that activates or increases the frequency, rate or extent of muscle hyperplasia."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0021511", "l": "spinal cord patterning", "d": ["The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021961", "l": "posterior commissure morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0099514", "l": "synaptic vesicle cytoskeletal transport", "d": ["The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000948", "l": "regulation of xyloglucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of xyloglucan metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0030261", "l": "chromosome condensation", "d": ["The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018893", "l": "dibenzofuran metabolic process", "d": ["The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042915", "l": "group A colicin transport", "d": ["The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003053", "l": "circadian regulation of heart rate", "d": ["Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098698", "l": "postsynaptic specialization assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0006206", "l": "pyrimidine nucleobase metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002941", "l": "synoviocyte proliferation", "d": ["The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003187", "l": "ventriculo bulbo valve morphogenesis", "d": ["The process in which the structure of the ventriculo bulbo valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "32.030975051093591", "identifiers": [{"i": "GO:0040016", "l": "embryonic cleavage", "d": ["The first few specialized divisions of an activated animal egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "38.105224564912184", "identifiers": [{"i": "GO:0002165", "l": "instar larval or pupal development", "d": ["The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902086", "l": "fumagillin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumagillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055112", "l": "delamination involved in gastrulation with mouth forming second", "d": ["The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010193", "l": "response to ozone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001076", "l": "positive regulation of metanephric ureteric bud development", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903032", "l": "negative regulation of microtubule plus-end binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009972", "l": "cytidine deamination", "d": ["The removal of amino group in the presence of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901883", "l": "4-hydroxycoumarin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0010421", "l": "hydrogen peroxide-mediated programmed cell death", "d": ["Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0050996", "l": "positive regulation of lipid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905528", "l": "positive regulation of Golgi lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042423", "l": "catecholamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030164", "l": "protein denaturation", "d": ["Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060535", "l": "trachea cartilage morphogenesis", "d": ["The process in which the anatomical structures of cartilage in the trachea are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141025", "l": "adhesion of symbiont to host cell surface via host glycoprotein", "d": ["The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034168", "l": "negative regulation of toll-like receptor 10 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043612", "l": "isoprene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoprene, C5H8."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060898", "l": "eye field cell fate commitment involved in camera-type eye formation", "d": ["The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048696", "l": "regulation of collateral sprouting in absence of injury", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061691", "l": "detoxification of hydrogen peroxide", "d": ["Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007396", "l": "suture of dorsal opening", "d": ["Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000310", "l": "regulation of NMDA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051795", "l": "positive regulation of timing of catagen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903197", "l": "positive regulation of L-dopa biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071347", "l": "cellular response to interleukin-1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0098035", "l": "viral DNA genome packaging via site-specific sequence recognition", "d": ["The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071220", "l": "cellular response to bacterial lipoprotein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071877", "l": "regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035495", "l": "regulation of SNARE complex disassembly", "d": ["Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061081", "l": "positive regulation of myeloid leukocyte cytokine production involved in immune response", "d": ["Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904995", "l": "negative regulation of leukocyte adhesion to vascular endothelial cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0072491", "l": "toluene-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031158", "l": "negative regulation of aggregate size involved in sorocarp development", "d": ["Any process that decreases the size of the aggregate formed during sorocarp formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0072243", "l": "metanephric nephron epithelium development", "d": ["The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061611", "l": "mannose to fructose-6-phosphate metabolic process", "d": ["The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048794", "l": "swim bladder development", "d": ["The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062164", "l": "regulation of pseudohyphal septin ring assembly", "d": ["Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905858", "l": "regulation of heparan sulfate proteoglycan binding", "d": ["Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071515", "l": "mating-type locus imprinting", "d": ["A genomic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035918", "l": "negative regulation of voltage-gated calcium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016113", "l": "polyterpenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060600", "l": "dichotomous subdivision of an epithelial terminal unit", "d": ["The process in which an epithelial cord, rod or tube bifurcates at its end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045781", "l": "negative regulation of cell budding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.095679833930788", "identifiers": [{"i": "GO:1901293", "l": "nucleoside phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019246", "l": "L(+)-lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0002701", "l": "negative regulation of production of molecular mediator of immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033298", "l": "contractile vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120094", "l": "negative regulation of peptidyl-lysine crotonylation", "d": ["Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014035", "l": "neural crest cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904956", "l": "regulation of midbrain dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0014037", "l": "Schwann cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903662", "l": "L-altrarate metabolic process", "d": ["The chemical reactions and pathways involving L-altrarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000343", "l": "positive regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061117", "l": "negative regulation of heart growth", "d": ["Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042264", "l": "peptidyl-aspartic acid hydroxylation", "d": ["The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046177", "l": "D-gluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032374", "l": "regulation of cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0120263", "l": "positive regulation of heterochromatin organization", "d": ["Any process that activates or increases the frequency, rate or extent of heterochromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035568", "l": "N-terminal peptidyl-proline methylation", "d": ["The methylation of the N-terminal proline of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006178", "l": "guanine salvage", "d": ["Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "39.042876286430278", "identifiers": [{"i": "GO:0023052", "l": "signaling", "d": ["The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002105", "l": "endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "d": ["Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071335", "l": "hair follicle cell proliferation", "d": ["The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071501", "l": "cellular response to sterol depletion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002546", "l": "negative regulation of tissue kallikrein-kinin cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905363", "l": "positive regulation of endosomal vesicle fusion", "d": ["Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039673", "l": "evasion by virus of host dendritic cell activity", "d": ["Any process by which a virus avoids the effects mediated by the host organism's dendritic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080034", "l": "host response to induction by symbiont of tumor, nodule or growth in host", "d": ["Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.518184511203678", "identifiers": [{"i": "GO:0006468", "l": "protein phosphorylation", "d": ["The process of introducing a phosphate group on to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0051568", "l": "histone H3-K4 methylation", "d": ["The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106115", "l": "negative regulation of mitotic cohesin dsDNA (leading strand) loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071871", "l": "response to epinephrine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905205", "l": "positive regulation of connective tissue replacement", "d": ["Any process that activates or increases the frequency, rate or extent of connective tissue replacement."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1901891", "l": "regulation of cell septum assembly", "d": ["Any process that modulates the frequency, rate or extent of cell septum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072218", "l": "metanephric ascending thin limb development", "d": ["The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901913", "l": "regulation of capsule organization", "d": ["Any process that modulates the frequency, rate or extent of capsule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900319", "l": "negative regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0019217", "l": "regulation of fatty acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048072", "l": "compound eye pigmentation", "d": ["Establishment of a pattern of pigment in the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072169", "l": "specification of posterior mesonephric tubule identity", "d": ["The process in which the tubules of the posterior mesonephros acquire their identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903565", "l": "negative regulation of protein localization to cilium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "30.085106882796598", "identifiers": [{"i": "GO:0048513", "l": "animal organ development", "d": ["Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0000050", "l": "urea cycle", "d": ["The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031063", "l": "regulation of histone deacetylation", "d": ["Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019478", "l": "D-amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902073", "l": "positive regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021699", "l": "cerebellar cortex maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0010906", "l": "regulation of glucose metabolic process", "d": ["Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002874", "l": "regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046866", "l": "tetraterpenoid transport", "d": ["The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002346", "l": "B cell positive selection", "d": ["Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014886", "l": "transition between slow and fast fiber", "d": ["The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000705", "l": "regulation of dense core granule biogenesis", "d": ["Any process that modulates the frequency, rate or extent of dense core granule biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000304", "l": "response to singlet oxygen", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904693", "l": "midbrain morphogenesis", "d": ["The developmental process by which a midbrain is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010364", "l": "regulation of ethylene biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033292", "l": "T-tubule organization", "d": ["A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0009713", "l": "catechol-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990383", "l": "cellular response to biotin starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018134", "l": "peptide cross-linking via glycine oxazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046169", "l": "methanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006383", "l": "transcription by RNA polymerase III", "d": ["The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097337", "l": "response to ziprasidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009127", "l": "purine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120140", "l": "negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901960", "l": "isobutanol metabolic process", "d": ["The chemical reactions and pathways involving isobutanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902685", "l": "positive regulation of receptor localization to synapse", "d": ["Any process that activates or increases the frequency, rate or extent of receptor localization to synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019411", "l": "aerobic respiration, using ferrous ions as electron donor", "d": ["The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902229", "l": "regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006176", "l": "dATP biosynthetic process from ADP", "d": ["The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009610", "l": "response to symbiotic fungus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090134", "l": "cell migration involved in mesendoderm migration", "d": ["The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014041", "l": "regulation of neuron maturation", "d": ["Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072566", "l": "chemokine (C-X-C motif) ligand 1 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014914", "l": "myoblast maturation involved in muscle regeneration", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070680", "l": "asparaginyl-tRNAAsn biosynthesis via transamidation", "d": ["A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097370", "l": "protein O-GlcNAcylation via threonine", "d": ["The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036155", "l": "acylglycerol acyl-chain remodeling", "d": ["Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008615", "l": "pyridoxine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900169", "l": "regulation of glucocorticoid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061186", "l": "negative regulation of silent mating-type cassette heterochromatin formation", "d": ["Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140194", "l": "negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905816", "l": "negative regulation of dorsal/ventral axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003075", "l": "renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure", "d": ["The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045225", "l": "negative regulation of CD4 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0002286", "l": "T cell activation involved in immune response", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033638", "l": "modulation by symbiont of host heat acclimation", "d": ["Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042832", "l": "defense response to protozoan", "d": ["Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1903326", "l": "regulation of tRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.661584743224637", "identifiers": [{"i": "GO:0050920", "l": "regulation of chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002396", "l": "MHC protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0050868", "l": "negative regulation of T cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060984", "l": "epicardium-derived cardiac vascular smooth muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106248", "l": "positive regulation of poly(A)-specific ribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046327", "l": "glycerol biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:1903169", "l": "regulation of calcium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0075528", "l": "perturbation by virus of host immune response", "d": ["A process in which a virus effects a change in the host immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006407", "l": "rRNA export from nucleus", "d": ["The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002323", "l": "natural killer cell activation involved in immune response", "d": ["The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034112", "l": "positive regulation of homotypic cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.152088137740293", "identifiers": [{"i": "GO:0002218", "l": "activation of innate immune response", "d": ["Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0140420", "l": "heme import into cell", "d": ["The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900092", "l": "negative regulation of raffinose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032710", "l": "negative regulation of interleukin-26 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046396", "l": "D-galacturonate metabolic process", "d": ["The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043301", "l": "negative regulation of leukocyte degranulation", "d": ["Any process that stops, prevents, or reduces the rate of leukocyte degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048681", "l": "negative regulation of axon regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0007498", "l": "mesoderm development", "d": ["The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. 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"100", "identifiers": [{"i": "GO:0018019", "l": "N-terminal peptidyl-glutamine methylation", "d": ["The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140430", "l": "positive regulation of chromosome passenger complex localization to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097638", "l": "L-arginine import across plasma membrane", "d": ["The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072756", "l": "cellular response to paraquat", "d": ["Any process that results in a change in state or activity of a 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[{"i": "GO:0003276", "l": "apoptotic process involved in heart valve morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0031346", "l": "positive regulation of cell projection organization", "d": ["Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060364", "l": "frontal suture morphogenesis", "d": ["The process in which the frontal suture is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060423", "l": "foregut regionalization", "d": ["The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000805", "l": "negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000088", "l": "mitotic prophase", "d": ["The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000650", "l": "negative regulation of sodium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000025", "l": "maltose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031646", "l": "positive regulation of nervous system process", "d": ["Any process that activates or increases the frequency, rate or extent of a neurophysiological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.55589269399384", "identifiers": [{"i": "GO:0071345", "l": "cellular response to cytokine stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071904", "l": "protein N-linked N-acetylgalactosaminylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048263", "l": "determination of dorsal identity", "d": ["Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032240", "l": "negative regulation of nucleobase-containing compound transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098713", "l": "leucine import across plasma membrane", "d": ["The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0030473", "l": "nuclear migration along microtubule", "d": ["The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900373", "l": "positive regulation of purine nucleotide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.597807799500664", "identifiers": [{"i": "GO:0032504", "l": "multicellular organism reproduction", "d": ["The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901509", "l": "regulation of endothelial tube morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070170", "l": "regulation of tooth mineralization", "d": ["Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902569", "l": "negative regulation of activation of Janus kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.51244992395911", "identifiers": [{"i": "GO:0006091", "l": "generation of precursor metabolites and energy", "d": ["The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904099", "l": "negative regulation of protein O-linked glycosylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009099", "l": "valine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006307", "l": "DNA dealkylation involved in DNA repair", "d": ["The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010890", "l": "positive regulation of sequestering of triglyceride", "d": ["Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045922", "l": "negative regulation of fatty acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060884", "l": "clearance of cells from fusion plate", "d": ["The morphogenetic process in which cells are removed from the inner loop of a semicircular canal."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060280", "l": "negative regulation of ovulation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031524", "l": "menthol metabolic process", "d": ["The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006666", "l": "3-keto-sphinganine metabolic process", "d": ["The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035211", "l": "spermathecum morphogenesis", "d": ["The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043683", "l": "type IV pilus assembly", "d": ["The assembly from its constituent parts of a type IV pilus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042689", "l": "regulation of crystal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of crystal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0009954", "l": "proximal/distal pattern formation", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036416", "l": "tRNA stabilization", "d": ["Prevention of degradation of tRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0044359", "l": "modulation of molecular function in another organism", "d": ["The process in which an organism effects a change in the function of proteins in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0106118", "l": "regulation of sterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a sterol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.145115725829193", "identifiers": [{"i": "GO:0051606", "l": "detection of stimulus", "d": ["The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080086", "l": "stamen filament development", "d": ["The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030263", "l": "apoptotic chromosome condensation", "d": ["The compaction of chromatin during apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0098900", "l": "regulation of action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072738", "l": "cellular response to diamide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061606", "l": "N-terminal protein amino acid propionylation", "d": ["The propionylation of the N-terminal amino acid of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000455", "l": "enzyme-directed rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0010976", "l": "positive regulation of neuron projection development", "d": ["Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031286", "l": "negative regulation of sorocarp stalk cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0160017", "l": "regulation of platelet rolling", "d": ["Any process that modulates the frequency, rate or extent of platelet rolling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021939", "l": "extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation", "d": ["The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060252", "l": "positive regulation of glial cell proliferation", "d": ["Any process that activates or increases the rate or extent of glial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035278", "l": "miRNA-mediated gene silencing by inhibition of translation", "d": ["An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0086067", "l": "AV node cell to bundle of His cell communication", "d": ["The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034477", "l": "U6 snRNA 3'-end processing", "d": ["Any process involved in forming the mature 3' end of a U6 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010950", "l": "positive regulation of endopeptidase activity", "d": ["Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009944", "l": "polarity specification of adaxial/abaxial axis", "d": ["The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003163", "l": "sinoatrial node development", "d": ["The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0001935", "l": "endothelial cell proliferation", "d": ["The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0002532", "l": "production of molecular mediator involved in inflammatory response", "d": ["The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060687", "l": "regulation of branching involved in prostate gland morphogenesis", "d": ["Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060725", "l": "regulation of coreceptor activity", "d": ["Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902288", "l": "regulation of defense response to oomycetes", "d": ["Any process that modulates the frequency, rate or extent of defense response to oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050984", "l": "peptidyl-serine sulfation", "d": ["The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090603", "l": "sieve element differentiation", "d": ["The process whereby a relatively unspecialized cell acquires specialized features of a sieve element."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.704640979746422", "identifiers": [{"i": "GO:0048762", "l": "mesenchymal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905255", "l": "regulation of RNA binding transcription factor activity", "d": ["Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0003263", "l": "cardioblast proliferation", "d": ["The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002401", "l": "tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT)."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051480", "l": "regulation of cytosolic calcium ion concentration", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072165", "l": "anterior mesonephric tubule development", "d": ["The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018895", "l": "dibenzothiophene metabolic process", "d": ["The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061106", "l": "negative regulation of stomach neuroendocrine cell differentiation", "d": ["Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901262", "l": "negative regulation of sorocarp spore cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035857", "l": "eosinophil fate specification", "d": ["The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0080144", "l": "intracellular amino acid homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.936984400389605", "identifiers": [{"i": "GO:1901360", "l": "organic cyclic compound metabolic process", "d": ["The chemical reactions and pathways involving organic cyclic compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015722", "l": "canalicular bile acid transport", "d": ["Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061195", "l": "taste bud formation", "d": ["The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0035788", "l": "cell migration involved in metanephros development", "d": ["The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039506", "l": "modulation by virus of host molecular function", "d": ["The process in which a virus effects a change in the function of a host protein via a direct interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036244", "l": "cellular response to neutral pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021701", "l": "cerebellar Golgi cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1903312", "l": "negative regulation of mRNA metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0009312", "l": "oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030399", "l": "autophagosome membrane disassembly", "d": ["The controlled breakdown of the membranes of autophagosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009910", "l": "negative regulation of flower development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of flower development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071045", "l": "nuclear histone mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0002517", "l": "T cell tolerance induction", "d": ["A process involving any mechanism for tolerance induction in T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002403", "l": "T cell tolerance induction in mucosal-associated lymphoid tissue", "d": ["Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070399", "l": "wall teichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033141", "l": "positive regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002584", "l": "negative regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902897", "l": "regulation of postsynaptic density protein 95 clustering", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090650", "l": "cellular response to oxygen-glucose deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900340", "l": "negative regulation of methane biosynthetic process from formic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane 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arginine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033657", "l": "disruption by symbiont of host chloroplast part", "d": ["The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031319", "l": "detection of cAMP", "d": ["The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0001504", "l": "neurotransmitter uptake", "d": ["The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072680", "l": "extracellular matrix-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048526", "l": "imaginal disc-derived wing expansion", "d": ["The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075520", "l": "actin-dependent intracellular transport of virus", "d": ["The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072102", "l": "glomerulus morphogenesis", "d": ["The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099509", "l": "regulation of presynaptic cytosolic calcium ion concentration", "d": ["Any process that regulates the concentration of calcium in the presynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901466", "l": "regulation of ferulate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of ferulate catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000671", "l": "regulation of motor neuron apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of motor neuron apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.492932992387935", "identifiers": [{"i": "GO:0001505", "l": "regulation of neurotransmitter levels", "d": ["Any process that modulates levels of neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010166", "l": "wax metabolic process", "d": ["The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000290", "l": "regulation of myotome development", "d": ["Any process that modulates the frequency, rate or extent of myotome development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002855", "l": "regulation of natural killer cell mediated immune response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905070", "l": "anterior visceral endoderm cell migration", "d": ["The orderly movement of an anterior visceral endoderm cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900449", "l": "regulation of glutamate receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903517", "l": "negative regulation of single strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0007316", "l": "pole plasm RNA localization", "d": ["Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002949", "l": "tRNA threonylcarbamoyladenosine modification", "d": ["The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051915", "l": "induction of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000447", "l": "negative regulation of macrophage migration inhibitory factor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051337", "l": "amitosis", "d": ["Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0048002", "l": "antigen processing and presentation of peptide antigen", "d": ["The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032537", "l": "host-seeking behavior", "d": ["The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106135", "l": "negative regulation of cardiac muscle cell contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060254", "l": "regulation of N-terminal protein palmitoylation", "d": ["Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904379", "l": "protein localization to cytosolic proteasome complex involved in ERAD pathway", "d": ["Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071296", "l": "cellular response to biotin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021579", "l": "medulla oblongata morphogenesis", "d": ["The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060062", "l": "Spemann organizer formation at the dorsal lip of the blastopore", "d": ["Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0015851", "l": "nucleobase transport", "d": ["The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021798", "l": "forebrain dorsal/ventral pattern formation", "d": ["The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019649", "l": "formaldehyde assimilation", "d": ["The pathways in which formaldehyde is processed and used as a carbon source for the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010733", "l": "positive regulation of protein glutathionylation", "d": ["Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905673", "l": "positive regulation of lysosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of lysosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903766", "l": "positive regulation of potassium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905790", "l": "regulation of mechanosensory behavior", "d": ["Any process that modulates the frequency, rate or extent of mechanosensory behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1901381", "l": "positive regulation of potassium ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902236", "l": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050946", "l": "positive regulation of xanthophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of xanthophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051788", "l": "response to misfolded protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097398", "l": "cellular response to interleukin-17", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007473", "l": "wing disc proximal/distal pattern formation", "d": ["The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075342", "l": "disruption by symbiont of host cell PML body", "d": ["The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060151", "l": "peroxisome localization", "d": ["Any process in which a peroxisome is transported to, and/or maintained in, a specific location. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002036", "l": "regulation of L-glutamate import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-glutamate import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1905809", "l": "negative regulation of synapse organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006738", "l": "nicotinamide riboside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0061037", "l": "negative regulation of cartilage development", "d": ["Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010043", "l": "response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900809", "l": "fumigaclavine C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fumigaclavine C, a fungal ergot alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901123", "l": "bacitracin A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacitracin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018955", "l": "phenanthrene metabolic process", "d": ["The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003218", "l": "cardiac left ventricle formation", "d": ["The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070834", "l": "phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035554", "l": "termination of Roundabout signal transduction", "d": ["The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902131", "l": "(+)-lariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0048144", "l": "fibroblast proliferation", "d": ["The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.005221697540719", "identifiers": [{"i": "GO:0046700", "l": "heterocycle catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021625", "l": "oculomotor nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000770", "l": "negative regulation of establishment or maintenance of cell polarity regulating cell shape", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903077", "l": "negative regulation of protein localization to plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080053", "l": "response to phenylalanine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000440", "l": "regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902176", "l": "negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905320", "l": "regulation of mesenchymal stem cell migration", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0010092", "l": "specification of animal organ identity", "d": ["The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046432", "l": "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process", "d": ["The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990167", "l": "protein K27-linked deubiquitination", "d": ["A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006678", "l": "glucosylceramide metabolic process", "d": ["The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900177", "l": "regulation of aflatoxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900979", "l": "positive regulation of tatiopterin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070413", "l": "trehalose metabolism in response to stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043327", "l": "chemotaxis to cAMP", "d": ["The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072142", "l": "juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002359", "l": "B-1 B cell proliferation", "d": ["The expansion of a B-1 B cell by cell division. Follows B cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046119", "l": "7-methylguanosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045997", "l": "negative regulation of ecdysteroid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044546", "l": "NLRP3 inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044127", "l": "regulation of development of symbiont in host", "d": ["Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001111", "l": "RNA polymerase II promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0017185", "l": "peptidyl-lysine hydroxylation", "d": ["The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061456", "l": "mesenchymal stem cell migration involved in uteric bud morphogenesis", "d": ["The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045680", "l": "negative regulation of R8 cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052865", "l": "1-deoxy-D-xylulose 5-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035262", "l": "gonad morphogenesis", "d": ["The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032261", "l": "purine nucleotide salvage", "d": ["Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046074", "l": "dTMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046295", "l": "glycolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0007128", "l": "meiotic prophase I", "d": ["The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.858950277264299", "identifiers": [{"i": "GO:0046651", "l": "lymphocyte proliferation", "d": ["The expansion of a lymphocyte population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051516", "l": "regulation of bipolar cell growth", "d": ["Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007055", "l": "spindle assembly involved in male meiosis II", "d": ["The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000093", "l": "regulation of mesonephric nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010510", "l": "regulation of acetyl-CoA biosynthetic process from pyruvate", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901164", "l": "negative regulation of trophoblast cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034963", "l": "box C/D RNA processing", "d": ["Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016134", "l": "saponin metabolic process", "d": ["The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0010154", "l": "fruit development", "d": ["The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902822", "l": "regulation of late endosome to lysosome transport", "d": ["Any process that modulates the frequency, rate or extent of late endosome to lysosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046514", "l": "ceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060149", "l": "negative regulation of post-transcriptional gene silencing", "d": ["Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014747", "l": "positive regulation of tonic skeletal muscle contraction", "d": ["Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045200", "l": "establishment of neuroblast polarity", "d": ["The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110002", "l": "regulation of tRNA methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905690", "l": "nucleus disassembly", "d": ["The disaggregation of a nucleus into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905541", "l": "regulation of L-arginine import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031650", "l": "regulation of heat generation", "d": ["Any process that modulates the rate or extent of heat generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072513", "l": "positive regulation of secondary heart field cardioblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033496", "l": "sinapate metabolic process", "d": ["The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0072485", "l": "response to spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051083", "l": "'de novo' cotranslational protein folding", "d": ["The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061077", "l": "chaperone-mediated protein folding", "d": ["The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045583", "l": "regulation of cytotoxic T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031366", "l": "N-terminal peptidyl-asparagine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0071921", "l": "cohesin loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120323", "l": "lipid ubiquitination", "d": ["The process in which one or more ubiquitin groups are added to a lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048533", "l": "sporocyte differentiation", "d": ["The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048855", "l": "adenohypophysis morphogenesis", "d": ["The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0021549", "l": "cerebellum development", "d": ["The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0042440", "l": "pigment metabolic process", "d": ["The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0006826", "l": "iron ion transport", "d": ["The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044525", "l": "peptidyl-cystine sulfhydration", "d": ["The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048455", "l": "stamen formation", "d": ["The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046443", "l": "FAD metabolic process", "d": ["The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060529", "l": "squamous basal epithelial stem cell differentiation involved in prostate gland acinus development", "d": ["The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903492", "l": "response to acetylsalicylate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000897", "l": "amylopectin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an amylopectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075300", "l": "negative regulation of zygospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075506", "l": "entry of viral genome into host nucleus through nuclear pore complex via importin", "d": ["Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002210", "l": "behavioral response to wounding", "d": ["A behavioral response resulting from wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901087", "l": "benzylpenicillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of benzylpenicillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060164", "l": "regulation of timing of neuron differentiation", "d": ["The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120303", "l": "visually-mediated background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018317", "l": "protein C-linked glycosylation via tryptophan", "d": ["The glycosylation of a carbon atom of a peptidyl-tryptophan residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019310", "l": "inositol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051485", "l": "terpenoid biosynthetic process, mevalonate-dependent", "d": ["The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045605", "l": "negative regulation of epidermal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032986", "l": "protein-DNA complex disassembly", "d": ["The disaggregation of a protein-DNA complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0006525", "l": "arginine metabolic process", "d": ["The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044795", "l": "trans-Golgi network to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097744", "l": "renal urate salt excretion", "d": ["The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0016068", "l": "type I hypersensitivity", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900598", "l": "demethylkotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of demethylkotanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019929", "l": "peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid", "d": ["The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001144", "l": "regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060405", "l": "regulation of penile erection", "d": ["Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905598", "l": "negative regulation of low-density lipoprotein receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071169", "l": "establishment of protein localization to chromatin", "d": ["The directed movement of a protein to a part of a chromosome that is organized into chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060056", "l": "mammary gland involution", "d": ["The tissue remodeling that removes differentiated mammary epithelia during weaning."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032376", "l": "positive regulation of cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904364", "l": "positive regulation of calcitonin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of calcitonin secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900633", "l": "pentadecane metabolic process", "d": ["The chemical reactions and pathways involving pentadecane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903885", "l": "negative regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051685", "l": "maintenance of ER location", "d": ["Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905945", "l": "regulation of response to calcium ion", "d": ["Any process that modulates the frequency, rate or extent of response to calcium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903100", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902464", "l": "regulation of histone H3-K27 trimethylation", "d": ["Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061669", "l": "spontaneous neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032723", "l": "positive regulation of connective tissue growth factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140732", "l": "positive regulation of amphiregulin production", "d": ["Any process that activates or increases the frequency, rate or extent of production of amphiregulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0043217", "l": "myelin maintenance", "d": ["The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016200", "l": "synaptic target attraction", "d": ["The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021896", "l": "forebrain astrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0010506", "l": "regulation of autophagy", "d": ["Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039504", "l": "suppression by virus of host adaptive immune response", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019602", "l": "toluene oxidation via 3-hydroxytoluene", "d": ["The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003055", "l": "circadian regulation of heart rate by the suprachiasmatic nucleus", "d": ["The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045035", "l": "sensory organ precursor cell division", "d": ["The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002845", "l": "positive regulation of tolerance induction to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032016", "l": "negative regulation of Ran protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043686", "l": "co-translational protein modification", "d": ["The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.735851798688778", "identifiers": [{"i": "GO:2000241", "l": "regulation of reproductive process", "d": ["Any process that modulates the frequency, rate or extent of reproductive process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0046777", "l": "protein autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904515", "l": "positive regulation of TORC2 signaling", "d": ["Any process that activates or increases the frequency, rate or extent of TORC2 signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061806", "l": "regulation of DNA recombination at centromere", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007141", "l": "male meiosis I", "d": ["A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062174", "l": "brexanolone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brexanolone."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032808", "l": "lacrimal gland development", "d": ["The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0002920", "l": "regulation of humoral immune response", "d": ["Any process that modulates the frequency, rate, or extent of a humoral immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901153", "l": "paromomycin metabolic process", "d": ["The chemical reactions and pathways involving paromomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080180", "l": "2-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 2-methylguanosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046517", "l": "octamethylcyclotetrasiloxane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002812", "l": "biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0040024", "l": "dauer larval development", "d": ["The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000144", "l": "positive regulation of DNA-templated transcription initiation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036368", "l": "cone photoresponse recovery", "d": ["The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003038", "l": "detection of reduced oxygen by aortic body chemoreceptor signaling", "d": ["The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060328", "l": "cytoplasmic actin-based contraction involved in forward cell motility", "d": ["The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002606", "l": "positive regulation of dendritic cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052573", "l": "UDP-D-galactose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009902", "l": "chloroplast relocation", "d": ["The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033360", "l": "lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060890", "l": "limb spinous cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106136", "l": "lectin-induced modified bacterial internalization", "d": ["The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045108", "l": "regulation of intermediate filament polymerization or depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071912", "l": "asynchronous neurotransmitter secretion", "d": ["Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901314", "l": "regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019322", "l": "pentose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.368095522595297", "identifiers": [{"i": "GO:0042537", "l": "benzene-containing compound metabolic process", "d": ["The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019283", "l": "L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000213", "l": "positive regulation of glutamate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003224", "l": "left ventricular compact myocardium morphogenesis", "d": ["The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990456", "l": "mitochondrion-endoplasmic reticulum membrane tethering", "d": ["The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009126", "l": "purine nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033543", "l": "fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903906", "l": "regulation of plasma membrane raft polarization", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane raft polarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061883", "l": "clathrin-dependent endocytosis involved in vitellogenesis", "d": ["A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904803", "l": "regulation of translation involved in cellular response to UV", "d": ["Any regulation of translation that is involved in cellular response to UV."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010664", "l": "negative regulation of striated muscle cell apoptotic process", "d": ["Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0009639", "l": "response to red or far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021516", "l": "dorsal spinal cord development", "d": ["The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0021605", "l": "cranial nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0045730", "l": "respiratory burst", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018070", "l": "peptidyl-serine phosphopantetheinylation", "d": ["The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0001659", "l": "temperature homeostasis", "d": ["A homeostatic process in which an organism modulates its internal body temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000953", "l": "branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032637", "l": "interleukin-8 production", "d": ["The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002725", "l": "negative regulation of T cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903742", "l": "regulation of anterograde synaptic vesicle transport", "d": ["Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902926", "l": "inulin metabolic process", "d": ["The chemical reactions and pathways involving inulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0071478", "l": "cellular response to radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900749", "l": "(R)-carnitine transport", "d": ["The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043054", "l": "dauer exit", "d": ["Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904836", "l": "facioacoustic ganglion morphogenesis", "d": ["The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000780", "l": "negative regulation of double-strand break repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000835", "l": "negative regulation of androgen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042040", "l": "metal incorporation into metallo-molybdopterin complex", "d": ["The incorporation of a metal into a metallo-molybdopterin complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015966", "l": "diadenosine tetraphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042245", "l": "RNA repair", "d": ["Any process that results in the repair of damaged RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036179", "l": "osteoclast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902858", "l": "propionyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving propionyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031322", "l": "ascospore-type prospore-specific spindle pole body remodeling", "d": ["A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904104", "l": "negative regulation of convergent extension involved in gastrulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0006953", "l": "acute-phase response", "d": ["An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0035215", "l": "genital disc development", "d": ["Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036031", "l": "recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex", "d": ["The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002815", "l": "biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905825", "l": "regulation of selenocysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of selenocysteine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902021", "l": "regulation of bacterial-type flagellum-dependent cell motility", "d": ["Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0002704", "l": "negative regulation of leukocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048205", "l": "COPI coating of Golgi vesicle", "d": ["The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905593", "l": "positive regulation of optical nerve axon regeneration", "d": ["Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060791", "l": "sebaceous gland placode formation", "d": ["The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905147", "l": "regulation of smooth muscle hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061556", "l": "trigeminal ganglion morphogenesis", "d": ["The process in which the anatomical structure of a trigeminal ganglion is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900829", "l": "D-tyrosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043149", "l": "stress fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075054", "l": "modulation of penetration peg formation", "d": ["Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021847", "l": "ventricular zone neuroblast division", "d": ["The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060778", "l": "primary leaflet morphogenesis", "d": ["The process in which the primary leaflet attains its shape. 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The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045766", "l": "positive regulation of angiogenesis", "d": ["Any process that activates or increases angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0006270", "l": "DNA replication initiation", "d": ["The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000866", "l": "positive regulation of estradiol secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estradiol secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0150106", "l": "regulation of protein localization to cell-cell junction", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0052314", "l": "phytoalexin metabolic process", "d": ["The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030854", "l": "positive regulation of granulocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of granulocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006599", "l": "phosphagen metabolic process", "d": ["The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160019", "l": "negative regulation of platelet rolling", "d": ["Any process that decreases the rate, frequency, or extent of platelet rolling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045316", "l": "negative regulation of compound eye photoreceptor development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902895", "l": "positive regulation of miRNA transcription", "d": ["Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035238", "l": "vitamin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.629028984204552", "identifiers": [{"i": "GO:0045058", "l": "T cell selection", "d": ["The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090511", "l": "periclinal cell division", "d": ["A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090436", "l": "leaf pavement cell development", "d": ["The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. 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A diuretic is an agent that promotes the excretion of urine through its effects on kidney function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051872", "l": "sphingosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033310", "l": "chlorophyll a catabolic process", "d": ["The chemical reactions and pathways leading to the breakdown of chlorophyll a."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009729", "l": "detection of brassinosteroid stimulus", "d": ["The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900753", "l": "doxorubicin transport", "d": ["The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034133", "l": "positive regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120093", "l": "regulation of peptidyl-lysine crotonylation", "d": ["Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061913", "l": "positive regulation of growth plate cartilage chondrocyte proliferation", "d": ["Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035545", "l": "determination of left/right asymmetry in nervous system", "d": ["The establishment of the nervous system with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007638", "l": "mechanosensory behavior", "d": ["Behavior that is dependent upon the sensation of a mechanical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007376", "l": "cephalic furrow formation", "d": ["Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. 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This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000738", "l": "positive regulation of stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014893", "l": "response to rest involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002107", "l": "generation of mature 3'-end of 5S rRNA generated by RNA polymerase III", "d": ["The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006611", "l": "protein export from nucleus", "d": ["The directed movement of a protein from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043463", "l": "regulation of rhamnose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0006665", "l": "sphingolipid metabolic process", "d": ["The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106272", "l": "protein localization to ERGIC", "d": ["A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021958", "l": "gracilis tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002522", "l": "leukocyte migration involved in immune response", "d": ["The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098544", "l": "maintenance of protein complex location", "d": ["Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015794", "l": "glycerol-3-phosphate transmembrane transport", "d": ["The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0048580", "l": "regulation of post-embryonic development", "d": ["Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905511", "l": "positive regulation of myosin II filament assembly", "d": ["Any process that activates or increases the frequency, rate or extent of myosin II filament assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072715", "l": "cellular response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0033006", "l": "regulation of mast cell activation involved in immune response", "d": ["Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901075", "l": "negative regulation of engulfment of apoptotic cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061941", "l": "positive regulation of c-di-GMP signaling", "d": ["Any process that increases the rate, frequency or extent of c-di-GMP signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017183", "l": "protein histidyl modification to diphthamide", "d": ["The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901269", "l": "lipooligosaccharide metabolic process", "d": ["The chemical reactions and pathways involving lipooligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018132", "l": "peptide cross-linking via L-cysteine oxazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032929", "l": "negative regulation of superoxide anion generation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901433", "l": "positive regulation of response to cycloalkane", "d": ["Any process that activates or increases the frequency, rate or extent of response to cycloalkane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043031", "l": "negative regulation of macrophage activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033233", "l": "regulation of protein sumoylation", "d": ["Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002900", "l": "positive regulation of central B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of central B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060572", "l": "morphogenesis of an epithelial bud", "d": ["The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0018315", "l": "molybdenum incorporation into molybdenum-molybdopterin complex", "d": ["The incorporation of molybdenum into a molybdenum-molybdopterin complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099557", "l": "trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044578", "l": "butyryl-CoA biosynthetic process", "d": ["The chemical reactions and pathway resulting in the formation of butyryl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002494", "l": "lipid antigen transport", "d": ["The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080177", "l": "plastoglobule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000674", "l": "regulation of type B pancreatic cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000472", "l": "negative regulation of hematopoietic stem cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0045745", "l": "positive regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0014855", "l": "striated muscle cell proliferation", "d": ["The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090706", "l": "specification of plant organ position", "d": ["The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901268", "l": "cephalosporin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cephalosporin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097119", "l": "postsynaptic density protein 95 clustering", "d": ["The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002583", "l": "regulation of antigen processing and presentation of peptide antigen", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061936", "l": "fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm", "d": ["The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904420", "l": "positive regulation of telomeric loop formation", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019600", "l": "toluene oxidation", "d": ["The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001247", "l": "positive regulation of phosphatidylcholine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018957", "l": "phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048730", "l": "epidermis morphogenesis", "d": ["The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046179", "l": "keto-D-gluconate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062001", "l": "negative regulation of cardiac endothelial to mesenchymal transition", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990110", "l": "callus formation", "d": ["The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900539", "l": "fumonisin metabolic process", "d": ["The chemical reactions and pathways involving fumonisin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000455", "l": "regulation of T-helper 17 cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0001569", "l": "branching involved in blood vessel morphogenesis", "d": ["The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system."]}]} {"type": "biolink:BiologicalProcess", "ic": "27.202429065809714", "identifiers": [{"i": "GO:0032501", "l": "multicellular organismal process", "d": ["Any biological process, occurring at the level of a multicellular organism, pertinent to its function."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0015807", "l": "L-amino acid transport", "d": ["The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0032092", "l": "positive regulation of protein binding", "d": ["Any process that activates or increases the frequency, rate or extent of protein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043942", "l": "negative regulation of sexual sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006122", "l": "mitochondrial electron transport, ubiquinol to cytochrome c", "d": ["The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0030593", "l": "neutrophil chemotaxis", "d": ["The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001325", "l": "formation of extrachromosomal circular DNA", "d": ["Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071907", "l": "determination of digestive tract left/right asymmetry", "d": ["Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002453", "l": "peripheral B cell anergy", "d": ["Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0006644", "l": "phospholipid metabolic process", "d": ["The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904093", "l": "negative regulation of autophagic cell death", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0030282", "l": "bone mineralization", "d": ["The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044836", "l": "D-xylose fermentation", "d": ["The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.85341545293393", "identifiers": [{"i": "GO:0070647", "l": "protein modification by small protein conjugation or removal", "d": ["A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001214", "l": "positive regulation of vasculogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of vasculogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039666", "l": "virion attachment to host cell pilus", "d": ["The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044479", "l": "envenomation resulting in modulation of mast cell degranulation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032323", "l": "lipoate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014060", "l": "regulation of epinephrine secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061485", "l": "memory T cell proliferation", "d": ["The expansion of a memory T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901303", "l": "negative regulation of cargo loading into COPII-coated vesicle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900395", "l": "negative regulation of kojic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048482", "l": "plant ovule morphogenesis", "d": ["The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051762", "l": "sesquiterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044351", "l": "macropinocytosis", "d": ["An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060382", "l": "regulation of DNA strand elongation", "d": ["Any process that modulates the rate, frequency or extent of DNA strand elongation. 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Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031282", "l": "regulation of guanylate cyclase activity", "d": ["Any process that modulates the frequency, rate or extent of guanylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901896", "l": "positive regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018061", "l": "peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine", "d": ["The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034296", "l": "zygospore formation", "d": ["The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075304", "l": "negative regulation of basidiospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.245311748130447", "identifiers": [{"i": "GO:0032368", "l": "regulation of lipid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046183", "l": "L-idonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051040", "l": "regulation of calcium-independent cell-cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071823", "l": "protein-carbohydrate complex subunit organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0035886", "l": "vascular associated smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090400", "l": "stress-induced premature senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0071826", "l": "protein-RNA complex organization", "d": ["Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070933", "l": "histone H4 deacetylation", "d": ["The modification of histone H4 by the removal of one or more acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.782924002860781", "identifiers": [{"i": "GO:0072527", "l": "pyrimidine-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905135", "l": "biotin import across plasma membrane", "d": ["The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901986", "l": "response to ketamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902119", "l": "regulation of meiotic spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of meiotic spindle elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0043447", "l": "alkane biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021848", "l": "neuroblast division in subpallium", "d": ["The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000804", "l": "regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901895", "l": "negative regulation of ATPase-coupled calcium transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002875", "l": "negative regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072700", "l": "response to bismuth", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036088", "l": "D-serine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0048247", "l": "lymphocyte chemotaxis", "d": ["The directed movement of a lymphocyte in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.527357013177497", "identifiers": [{"i": "GO:0044238", "l": "primary metabolic process", "d": ["The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. 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The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060270", "l": "main body follicle cell migration", "d": ["The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035729", "l": "cellular response to hepatocyte growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062107", "l": "regulation of protein localization to non-growing cell tip", "d": ["Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901797", "l": "negative regulation of signal transduction by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0044458", "l": "motile cilium assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a motile cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0002886", "l": "regulation of myeloid leukocyte mediated immunity", "d": ["Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901061", "l": "guaiacyl lignin metabolic process", "d": ["The chemical reactions and pathways involving guaiacyl lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032538", "l": "regulation of host-seeking behavior", "d": ["Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0070341", "l": "fat cell proliferation", "d": ["The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0000271", "l": "polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.594400196502249", "identifiers": [{"i": "GO:0072028", "l": "nephron morphogenesis", "d": ["The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060711", "l": "labyrinthine layer development", "d": ["The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070426", "l": "positive regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033259", "l": "plastid DNA replication", "d": ["The process in which new strands of DNA are synthesized in a plastid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098829", "l": "intestinal folate absorption", "d": ["Uptake of folic into the blood by absorption from the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000289", "l": "nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031413", "l": "regulation of buoyancy", "d": ["Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901079", "l": "positive regulation of relaxation of muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0050915", "l": "sensory perception of sour taste", "d": ["The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904360", "l": "negative regulation of spore germination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spore germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045660", "l": "positive regulation of neutrophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021905", "l": "forebrain-midbrain boundary formation", "d": ["The process whose specific outcome is the creation of the forebrain-midbrain boundary."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.272121670738876", "identifiers": [{"i": "GO:0006629", "l": "lipid metabolic process", "d": ["The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046059", "l": "dAMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0002294", "l": "CD4-positive, alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072629", "l": "interleukin-28B production", "d": ["The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902466", "l": "positive regulation of histone H3-K27 trimethylation", "d": ["Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905213", "l": "negative regulation of mitotic chromosome condensation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046451", "l": "diaminopimelate metabolic process", "d": ["The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.668081988194295", "identifiers": [{"i": "GO:0042110", "l": "T cell activation", "d": ["The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905130", "l": "carcinine import across plasma membrane", "d": ["The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006127", "l": "glycerophosphate shuttle", "d": ["The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903396", "l": "negative regulation of secondary cell septum biogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031647", "l": "regulation of protein stability", "d": ["Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044361", "l": "negative regulation of voltage-gated potassium channel activity in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075225", "l": "negative regulation of sporangium germination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031990", "l": "mRNA export from nucleus in response to heat stress", "d": ["The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010934", "l": "macrophage cytokine production", "d": ["The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061359", "l": "regulation of Wnt signaling pathway by Wnt protein secretion", "d": ["Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000678", "l": "negative regulation of transcription regulatory region DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901413", "l": "regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032415", "l": "regulation of sodium:proton antiporter activity", "d": ["Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072336", "l": "negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902797", "l": "negative regulation of snoRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901559", "l": "response to ribavirin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000958", "l": "negative regulation of cyclodextrin 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009865", "l": "pollen tube adhesion", "d": ["The process in which the pollen tube adheres to cells of the stigma and style."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002628", "l": "regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0007624", "l": "ultradian rhythm", "d": ["The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099161", "l": "regulation of presynaptic dense core granule exocytosis", "d": ["Any process that modulates the frequency, rate or extent of 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"lateral growth", "d": ["Growth of a plant axis (shoot axis or root) that originates from a lateral meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905420", "l": "vascular associated smooth muscle cell differentiation involved in phenotypic switching", "d": ["Any vascular smooth muscle cell differentiation that is involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901327", "l": "response to tacrolimus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0001582", "l": "detection of chemical stimulus involved in sensory perception of sweet taste", "d": ["The series of events required for a sweet taste stimulus to be received and converted to a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901430", "l": "positive regulation of syringal lignin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006582", "l": "melanin metabolic process", "d": ["The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046780", "l": "suppression by virus of host mRNA splicing", "d": ["Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050965", "l": "detection of temperature stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061510", "l": "asymmetric protein localization to new mitotic spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071349", "l": "cellular response to interleukin-12", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990927", "l": "calcium ion regulated lysosome exocytosis", "d": ["The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009236", "l": "cobalamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905219", "l": "regulation of platelet formation", "d": ["Any process that modulates the frequency, rate or extent of platelet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060950", "l": "cardiac glial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014849", "l": "ureter smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009750", "l": "response to fructose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010036", "l": "response to boron-containing substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090050", "l": "positive regulation of cell migration involved in sprouting angiogenesis", "d": ["Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.052146566951166", "identifiers": [{"i": "GO:0010468", "l": "regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032939", "l": "positive regulation of translation in response to oxidative stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042869", "l": "aldarate transmembrane transport", "d": ["The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032095", "l": "regulation of response to food", "d": ["Any process that modulates the frequency, rate or extent of a response to a food stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042547", "l": "cell wall modification involved in multidimensional cell growth", "d": ["The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000269", "l": "regulation of fibroblast apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of fibroblast apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0035194", "l": "regulatory ncRNA-mediated post-transcriptional gene silencing", "d": ["A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000228", "l": "positive regulation of pancreatic A cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070415", "l": "trehalose metabolism in response to cold stress", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071500", "l": "cellular response to nitrosative stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904662", "l": "positive regulation of sensory perception of bitter taste", "d": ["Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021755", "l": "eurydendroid cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904801", "l": "positive regulation of neuron remodeling", "d": ["Any process that activates or increases the frequency, rate or extent of neuron remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000593", "l": "negative regulation of metanephric DCT cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009969", "l": "xyloglucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044868", "l": "modulation by host of viral molecular function", "d": ["A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000199", "l": "positive regulation of ribonucleoprotein complex localization", "d": ["Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904233", "l": "negative regulation of aconitate hydratase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000621", "l": "regulation of DNA replication termination", "d": ["Any process that modulates the frequency, rate or extent of DNA replication termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048650", "l": "caste determination, influence by environmental factors", "d": ["The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090364", "l": "regulation of proteasome assembly", "d": ["Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019289", "l": "rhizobactin 1021 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009686", "l": "gibberellin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072278", "l": "metanephric comma-shaped body morphogenesis", "d": ["The process in which the metanephric comma-shaped body is generated and organized. 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"ic": "89.347505587204751", "identifiers": [{"i": "GO:0015889", "l": "cobalamin transport", "d": ["The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010395", "l": "rhamnogalacturonan I metabolic process", "d": ["The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050841", "l": 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"identifiers": [{"i": "GO:0015949", "l": "nucleobase-containing small molecule interconversion", "d": ["The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000980", "l": "regulation of inner ear receptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900002", "l": "positive regulation of anthocyanin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902058", "l": "regulation of sporocarp development involved in sexual 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0072339", "l": "lactam biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051012", "l": "microtubule sliding", "d": ["The movement of one microtubule along another microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061223", "l": "mesonephric mesenchymal cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002473", "l": "non-professional antigen presenting cell antigen processing and presentation", "d": ["The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0009996", "l": "negative regulation of cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from adopting a specific cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901017", "l": "negative regulation of potassium ion transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0071331", "l": "cellular response to hexose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905387", "l": "response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061443", "l": "endocardial cushion cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043030", "l": "regulation of macrophage activation", "d": ["Any process that modulates the frequency or rate of macrophage activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903328", "l": "positive regulation of tRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042790", "l": "nucleolar large rRNA transcription by RNA polymerase I", "d": ["The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007448", "l": "anterior/posterior pattern specification, imaginal disc", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. 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An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015799", "l": "propanediol transport", "d": ["The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032726", "l": "positive regulation of hepatocyte growth factor production", "d": ["Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.441195081532641", "identifiers": [{"i": "GO:0001558", "l": "regulation of cell growth", "d": ["Any process that modulates the frequency, rate, extent or direction of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090606", "l": "single-species surface biofilm formation", "d": ["A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903751", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140914", "l": "zinc ion import into secretory vesicle", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a secretory vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0042632", "l": "cholesterol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905631", "l": "cellular response to glyceraldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033008", "l": "positive regulation of mast cell activation involved in immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019451", "l": "L-cysteine catabolic process to pyruvate, using cysteine dioxygenase", "d": ["The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006798", "l": "polyphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006121", "l": "mitochondrial electron transport, succinate to ubiquinone", "d": ["The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140380", "l": "psilocybin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903612", "l": "positive regulation of calcium-dependent ATPase activity", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051565", "l": "negative regulation of smooth endoplasmic reticulum calcium ion concentration", "d": ["Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:0060179", "l": "male mating behavior", "d": ["The specific behavior of a male organism that is associated with reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039686", "l": "bidirectional double-stranded viral DNA replication", "d": ["A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048149", "l": "behavioral response to ethanol", "d": ["Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097213", "l": "regulation of lysosomal membrane permeability", "d": ["Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904130", "l": "regulation of convergent extension involved in neural plate elongation", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018275", "l": "N-terminal peptidyl-cysteine acetylation", "d": ["The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0033280", "l": "response to vitamin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072703", "l": "cellular response to methyl methanesulfonate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039557", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904338", "l": "regulation of dopaminergic neuron differentiation", "d": ["Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0034404", "l": "nucleobase-containing small molecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048169", "l": "regulation of long-term neuronal synaptic plasticity", "d": ["A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0006986", "l": "response to unfolded protein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0000018", "l": "regulation of DNA recombination", "d": ["Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106107", "l": "regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:1903053", "l": "regulation of extracellular matrix organization", "d": ["Any process that modulates the frequency, rate or extent of extracellular matrix organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902564", "l": "negative regulation of neutrophil activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0030324", "l": "lung development", "d": ["The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010775", "l": "meiotic strand invasion involved in meiotic gene conversion", "d": ["The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018906", "l": "methyl tert-butyl ether metabolic process", "d": ["The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062173", "l": "brexanolone metabolic process", "d": ["The chemical reactions and pathways by which living organisms transform brexanolone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021519", "l": "spinal cord association neuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033400", "l": "trans-zeatin metabolic process", "d": ["The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055091", "l": "phospholipid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002876", "l": "positive regulation of chronic inflammatory response to antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048335", "l": "negative regulation of mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003259", "l": "cardioblast anterior-lateral migration", "d": ["The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046774", "l": "suppression by virus of host intracellular interferon activity", "d": ["Any viral process that results in the inhibition of interferon activity within the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1901298", "l": "regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035571", "l": "N-terminal peptidyl-serine monomethylation", "d": ["The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000693", "l": "positive regulation of seed maturation", "d": ["Any process that activates or increases the frequency, rate or extent of seed maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000587", "l": "negative regulation of platelet-derived growth factor receptor-beta signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070964", "l": "positive regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072248", "l": "metanephric podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001049", "l": "regulation of tendon cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of tendon cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045812", "l": "negative regulation of Wnt signaling pathway, calcium modulating pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061713", "l": "anterior neural tube closure", "d": ["The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045855", "l": "negative regulation of pole plasm oskar mRNA localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019603", "l": "toluene oxidation via 4-hydroxytoluene", "d": ["The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099138", "l": "altruistic, chimeric sorocarp development", "d": ["Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901436", "l": "positive regulation of toluene catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of toluene catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048564", "l": "photosystem I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000735", "l": "removal of nonhomologous ends", "d": ["The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902071", "l": "regulation of hypoxia-inducible factor-1alpha signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036249", "l": "cadmium ion import into vacuole", "d": ["The directed movement of cadmium ions into the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905382", "l": "positive regulation of snRNA transcription by RNA polymerase II", "d": ["Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150045", "l": "regulation of synaptic signaling by nitric oxide", "d": ["Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071975", "l": "cell swimming", "d": ["Cell motility that results in the smooth movement of a cell through a liquid medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0030421", "l": "defecation", "d": ["The expulsion of feces from the rectum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001757", "l": "somite specification", "d": ["The process in which individual somites establish identity during embryogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903248", "l": "regulation of citrulline biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of citrulline biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903501", "l": "positive regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901915", "l": "positive regulation of capsule organization", "d": ["Any process that activates or increases the frequency, rate or extent of capsule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006269", "l": "DNA replication, synthesis of RNA primer", "d": ["The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036268", "l": "swimming", "d": ["Self-propelled movement of an organism from one location to another through water, often by means of active fin movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045947", "l": "negative regulation of translational initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000449", "l": "regulation of CD8-positive, alpha-beta T cell extravasation", "d": ["Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0006706", "l": "steroid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150143", "l": "regulation of CD80 production", "d": ["Any process that modulates the frequency, rate or extent of CD80 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061173", "l": "positive regulation of establishment of bipolar cell polarity", "d": ["Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0005999", "l": "xylulose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071528", "l": "tRNA re-export from nucleus", "d": ["The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010218", "l": "response to far red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061765", "l": "perturbation by virus of host non-canonical NF-kappaB signal transduction", "d": ["A process in which a symbiont alters or subverts a non-canonical NF-kappaB signaling cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061848", "l": "cellular response to cholecystokinin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140141", "l": "mitochondrial potassium ion transmembrane transport", "d": ["The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002587", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.937454763326897", "identifiers": [{"i": "GO:0007409", "l": "axonogenesis", "d": ["De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010460", "l": "positive regulation of heart rate", "d": ["Any process that activates or increases the frequency or rate of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007279", "l": "pole cell formation", "d": ["Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071323", "l": "cellular response to chitin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.623410725809201", "identifiers": [{"i": "GO:0051640", "l": "organelle localization", "d": ["Any process in which an organelle is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902164", "l": "positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071961", "l": "mitotic sister chromatid cohesion, arms", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035703", "l": "monocyte migration into blood stream", "d": ["The movement of a monocyte from the bone marrow to the blood stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035018", "l": "adult chitin-based cuticle pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060861", "l": "positive regulation of floral organ abscission", "d": ["Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904782", "l": "negative regulation of NMDA glutamate receptor activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052086", "l": "suppression of host B-cell mediated immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010711", "l": "negative regulation of collagen catabolic process", "d": ["Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140325", "l": "negative regulation of protein localization to medial cortex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006528", "l": "asparagine metabolic process", "d": ["The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061159", "l": "establishment of bipolar cell polarity involved in cell morphogenesis", "d": ["The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019266", "l": "asparagine biosynthetic process from oxaloacetate", "d": ["The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905146", "l": "lysosomal protein catabolic process", "d": ["Any cellular protein catabolic process that takes place in a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090528", "l": "smooth septate junction assembly", "d": ["The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051262", "l": "protein tetramerization", "d": ["The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003092", "l": "renal water retention", "d": ["The process in which renal water excretion is decreased."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060244", "l": "negative regulation of cell proliferation involved in contact inhibition", "d": ["Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032715", "l": "negative regulation of interleukin-6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904986", "l": "positive regulation of quinolinate biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903057", "l": "negative regulation of melanosome organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902007", "l": "regulation of toxin transport", "d": ["Any process that modulates the frequency, rate or extent of toxin transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043586", "l": "tongue development", "d": ["The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0039663", "l": "membrane fusion involved in viral entry into host cell", "d": ["Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990564", "l": "protein polyufmylation", "d": ["Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000441", "l": "negative regulation of toll-like receptor 15 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0001835", "l": "blastocyst hatching", "d": ["The hatching of the cellular blastocyst from the zona pellucida."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000056", "l": "ribosomal small subunit export from nucleus", "d": ["The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000624", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021976", "l": "medulla reticulospinal tract morphogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900205", "l": "apoptotic process involved in metanephric nephron tubule development", "d": ["Any apoptotic process that is involved in metanephric nephron tubule development."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051153", "l": "regulation of striated muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of striated muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018907", "l": "dimethyl sulfoxide metabolic process", "d": ["The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051626", "l": "regulation of epinephrine uptake", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046398", "l": "UDP-glucuronate metabolic process", "d": ["The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034067", "l": "protein localization to Golgi apparatus", "d": ["A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0093001", "l": "glycolysis from storage polysaccharide through glucose-1-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.78964318410506", "identifiers": [{"i": "GO:0042640", "l": "anagen", "d": ["The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009567", "l": "double fertilization forming a zygote and endosperm", "d": ["Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051069", "l": "galactomannan metabolic process", "d": ["The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060686", "l": "negative regulation of prostatic bud formation", "d": ["Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904543", "l": "negative regulation of free ubiquitin chain polymerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046690", "l": "response to tellurium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140192", "l": "regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990397", "l": "queuosine salvage", "d": ["Any process which produces queuosine from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071277", "l": "cellular response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905305", "l": "negative regulation of cardiac myofibril assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0007029", "l": "endoplasmic reticulum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010425", "l": "DNA methylation on cytosine within a CNG sequence", "d": ["The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042488", "l": "positive regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903229", "l": "xanthosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of xanthosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014853", "l": "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction", "d": ["Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070301", "l": "cellular response to hydrogen peroxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009644", "l": "response to high light intensity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019264", "l": "glycine biosynthetic process from serine", "d": ["The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032599", "l": "protein transport out of membrane raft", "d": ["The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098005", "l": "viral head-tail joining", "d": ["Process by which virus heads and tails are attached to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080193", "l": "diffuse secondary thickening", "d": ["Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0048645", "l": "animal organ formation", "d": ["The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0001771", "l": "immunological synapse formation", "d": ["The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035750", "l": "protein localization to myelin sheath abaxonal region", "d": ["Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030842", "l": "regulation of intermediate filament depolymerization", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0141067", "l": "intracellular nitrogen homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990969", "l": "modulation by host of viral RNA-binding transcription factor activity", "d": ["A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031054", "l": "pre-miRNA processing", "d": ["A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032219", "l": "cell wall macromolecule catabolic process involved in cytogamy", "d": ["The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062010", "l": "primitive palate development", "d": ["The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036197", "l": "zymosterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905186", "l": "regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021507", "l": "posterior neuropore closure", "d": ["The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140588", "l": "chromatin looping", "d": ["A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090192", "l": "regulation of glomerulus development", "d": ["Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000444", "l": "negative regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0072012", "l": "glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014707", "l": "branchiomeric skeletal muscle development", "d": ["The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060549", "l": "regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "d": ["Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035696", "l": "monocyte extravasation", "d": ["The migration of a monocyte from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048697", "l": "positive regulation of collateral sprouting in absence of injury", "d": ["Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010833", "l": "telomere maintenance via telomere lengthening", "d": ["Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.735851798688778", "identifiers": [{"i": "GO:0006816", "l": "calcium ion transport", "d": ["The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0043392", "l": "negative regulation of DNA binding", "d": ["Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035207", "l": "negative regulation of hemocyte proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0001657", "l": "ureteric bud development", "d": ["The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902438", "l": "response to vanadate(3-)", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150140", "l": "regulation of CD86 production", "d": ["Any process that modulates the frequency, rate or extent of CD86 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009157", "l": "deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902219", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0002690", "l": "positive regulation of leukocyte chemotaxis", "d": ["Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902563", "l": "regulation of neutrophil activation", "d": ["Any process that modulates the frequency, rate or extent of neutrophil activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032985", "l": "protein-carbohydrate complex disassembly", "d": ["The disaggregation of a protein-carbohydrate complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0014003", "l": "oligodendrocyte development", "d": ["The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903064", "l": "positive regulation of reverse cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045050", "l": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140743", "l": "regulation of lncRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900222", "l": "negative regulation of amyloid-beta clearance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000400", "l": "positive regulation of thymocyte aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of thymocyte aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051106", "l": "positive regulation of DNA ligation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051292", "l": "nuclear pore complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006973", "l": "intracellular accumulation of glycerol", "d": ["The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0120261", "l": "regulation of heterochromatin organization", "d": ["Any process that modulates the frequency, rate, extent or location of heterochromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903564", "l": "regulation of protein localization to cilium", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0002483", "l": "antigen processing and presentation of endogenous peptide antigen", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032530", "l": "regulation of microvillus organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902762", "l": "regulation of embryonic skeletal joint development", "d": ["Any process that modulates the frequency, rate or extent of embryonic skeletal joint development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051005", "l": "negative regulation of lipoprotein lipase activity", "d": ["Any process that stops or reduces the activity of the enzyme lipoprotein lipase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062248", "l": "cleistothecium formation", "d": ["The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018985", "l": "pronuclear envelope synthesis", "d": ["Synthesis and ordering of the envelope of pronuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0008306", "l": "associative learning", "d": ["Learning by associating a stimulus (the cause) with a particular outcome (the effect)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0009813", "l": "flavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0044277", "l": "cell wall disassembly", "d": ["A process that results in the breakdown of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051028", "l": "mRNA transport", "d": ["The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905119", "l": "response to haloperidol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000958", "l": "mitochondrial mRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001299", "l": "N(omega),N(omega)-dimethyl-L-arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000055", "l": "positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification", "d": ["Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902573", "l": "positive regulation of serine-type peptidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902913", "l": "positive regulation of neuroepithelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060875", "l": "lateral semicircular canal development", "d": ["The progession of the lateral semicircular canal from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0031033", "l": "myosin filament organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905287", "l": "positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation", "d": ["Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060999", "l": "positive regulation of dendritic spine development", "d": ["Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098877", "l": "neurotransmitter receptor transport to plasma membrane", "d": ["The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.648646756982281", "identifiers": [{"i": "GO:0050882", "l": "voluntary musculoskeletal movement", "d": ["The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001108", "l": "positive regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0039674", "l": "exit of virus from host cell nucleus", "d": ["The directed movement of the viral genome or a viral particle out of the host cell nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903817", "l": "negative regulation of voltage-gated potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061481", "l": "response to TNF agonist", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010129", "l": "anaerobic cyclohexane-1-carboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043153", "l": "entrainment of circadian clock by photoperiod", "d": ["The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048719", "l": "epistomal sclerite morphogenesis", "d": ["The process in which the anatomical structures of the epistomal sclerite are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0022400", "l": "regulation of rhodopsin mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140645", "l": "neutrophic extracellular trap formation", "d": ["The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006012", "l": "galactose metabolic process", "d": ["The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009432", "l": "SOS response", "d": ["An error-prone process for repairing damaged microbial DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090250", "l": "cell-cell adhesion involved in establishment of planar polarity", "d": ["The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900757", "l": "regulation of D-amino-acid oxidase activity", "d": ["Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051478", "l": "mannosylglycerate metabolic process", "d": ["The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090638", "l": "phosphatidylcholine biosynthesis from phosphatidylethanolamine", "d": ["The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019759", "l": "glycosinolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006596", "l": "polyamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045748", "l": "positive regulation of R8 cell spacing in compound eye", "d": ["Any process that activates or enforces the correct R8 cell spacing in a compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0002088", "l": "lens development in camera-type eye", "d": ["The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042387", "l": "plasmatocyte differentiation", "d": ["The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072267", "l": "metanephric capsule specification", "d": ["The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905602", "l": "positive regulation of receptor-mediated endocytosis involved in cholesterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009231", "l": "riboflavin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002689", "l": "negative regulation of leukocyte chemotaxis", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034218", "l": "ascospore wall chitin metabolic process", "d": ["The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900837", "l": "regulation of fumigaclavine C biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032648", "l": "regulation of interferon-beta production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-beta production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009103", "l": "lipopolysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140438", "l": "protein stearoylation", "d": ["The covalent attachment of a stearoyl group to an amino acid in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000708", "l": "meiotic strand invasion", "d": ["The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048505", "l": "regulation of timing of cell differentiation", "d": ["The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0051303", "l": "establishment of chromosome localization", "d": ["The directed movement of a chromosome to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010656", "l": "negative regulation of muscle cell apoptotic process", "d": ["Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905157", "l": "positive regulation of photosynthesis", "d": ["Any process that activates or increases the frequency, rate or extent of photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061794", "l": "conidium development", "d": ["The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030199", "l": "collagen fibril organization", "d": ["Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110147", "l": "protein maturation by nickel ion transfer", "d": ["A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046519", "l": "sphingoid metabolic process", "d": ["The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090170", "l": "regulation of Golgi inheritance", "d": ["Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120311", "l": "ciliary pro-basal body maturation", "d": ["A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060058", "l": "positive regulation of apoptotic process involved in mammary gland involution", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000001", "l": "mitochondrion inheritance", "d": ["The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0071806", "l": "protein transmembrane transport", "d": ["The process in which a protein is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051623", "l": "positive regulation of norepinephrine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072178", "l": "nephric duct morphogenesis", "d": ["The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070391", "l": "response to lipoteichoic acid", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140624", "l": "EGAD pathway", "d": ["The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009875", "l": "pollen-pistil interaction", "d": ["The interaction between a pollen grain and pistil."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099606", "l": "microtubule plus-end directed mitotic chromosome migration", "d": ["The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030886", "l": "negative regulation of myeloid dendritic cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048937", "l": "lateral line nerve glial cell development", "d": ["The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0099072", "l": "regulation of postsynaptic membrane neurotransmitter receptor levels", "d": ["Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046587", "l": "positive regulation of calcium-dependent cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002511", "l": "central B cell receptor editing", "d": ["Receptor editing occurring in B cells in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900672", "l": "positive regulation of F-9775A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0055119", "l": "relaxation of cardiac muscle", "d": ["The process in which the extent of cardiac muscle contraction is reduced."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002048", "l": "pyoverdine metabolic process", "d": ["The chemical reactions and pathways involving the siderochrome pyoverdine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035815", "l": "positive regulation of renal sodium excretion", "d": ["Any process that increases the amount of sodium excreted in urine over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018872", "l": "arsonoacetate metabolic process", "d": ["The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048453", "l": "sepal formation", "d": ["The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060695", "l": "negative regulation of cholesterol transporter activity", "d": ["Any process that decreases the rate, frequency, or extent of cholesterol transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035155", "l": "negative regulation of terminal cell fate specification, open tracheal system", "d": ["Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.800603314158678", "identifiers": [{"i": "GO:0016071", "l": "mRNA metabolic process", "d": ["The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.858217064347613", "identifiers": [{"i": "GO:0048518", "l": "positive regulation of biological process", "d": ["Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001034", "l": "positive regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042270", "l": "protection from natural killer cell mediated cytotoxicity", "d": ["The process of protecting a cell from natural killer cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903699", "l": "tarsal gland development", "d": ["The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901400", "l": "positive regulation of transforming growth factor beta3 activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015677", "l": "copper ion import", "d": ["The directed movement of copper ions into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006888", "l": "endoplasmic reticulum to Golgi vesicle-mediated transport", "d": ["The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044209", "l": "AMP salvage", "d": ["The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000085", "l": "mitotic G2 phase", "d": ["The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001150", "l": "positive regulation of dipeptide transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032675", "l": "regulation of interleukin-6 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-6 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051514", "l": "negative regulation of monopolar cell growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000128", "l": "regulation of octopamine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of octopamine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044854", "l": "plasma membrane raft assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000875", "l": "negative regulation of glyoxylate cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900088", "l": "regulation of inositol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of inositol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009130", "l": "pyrimidine nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021630", "l": "olfactory nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150136", "l": "regulation of interleukin-37 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-37 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140647", "l": "P450-containing electron transport chain", "d": ["A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905520", "l": "positive regulation of presynaptic active zone assembly", "d": ["Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019095", "l": "pole plasm mitochondrial rRNA localization", "d": ["Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902836", "l": "positive regulation of proline import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of proline import into cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032056", "l": "positive regulation of translation in response to stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.041249355605835", "identifiers": [{"i": "GO:0040012", "l": "regulation of locomotion", "d": ["Any process that modulates the frequency, rate or extent of locomotion of a cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002341", "l": "central B cell anergy", "d": ["Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900708", "l": "negative regulation of tensidol A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050842", "l": "copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide", "d": ["The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905589", "l": "positive regulation of L-arginine import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046452", "l": "dihydrofolate metabolic process", "d": ["The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044072", "l": "suppression of host cell cycle progression", "d": ["A process in which a symbiont interferes with, inhibits or stops progression through the host cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009860", "l": "pollen tube growth", "d": ["Growth of pollen via tip extension of the intine wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990784", "l": "response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072250", "l": "metanephric podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904014", "l": "response to serotonin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120116", "l": "glucagon processing", "d": ["The formation of mature glucagon by proteolysis of the precursor proglucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035988", "l": "chondrocyte proliferation", "d": ["The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900744", "l": "regulation of p38MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of p38MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002763", "l": "positive regulation of myeloid leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060466", "l": "activation of meiosis involved in egg activation", "d": ["Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006349", "l": "regulation of gene expression by genomic imprinting", "d": ["An epigenetic mechanism of regulation of gene expression in which epigenetic modifications (imprints) are established during gametogenesis. For a given gene to show parentally biased expression, the imprint are established exclusively in one of the two parental genomes, thus generating an asymmetry between the maternal and paternal alleles."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060684", "l": "epithelial-mesenchymal cell signaling", "d": ["Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032812", "l": "positive regulation of epinephrine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044762", "l": "negative regulation by symbiont of host neurotransmitter secretion", "d": ["Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0106295", "l": "resolvin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034287", "l": "detection of monosaccharide stimulus", "d": ["The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039592", "l": "perturbation by virus of G2/M transition of host mitotic cell cycle", "d": ["A process in which a virus interferes with the progression of the host mitotic cell cycle from G2 phase to M phase, leading to arrest in G2 phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048539", "l": "bone marrow development", "d": ["The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904881", "l": "cellular response to hydrogen sulfide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045220", "l": "positive regulation of FasL production", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001059", "l": "D-tagatose 6-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075247", "l": "aeciospore formation", "d": ["The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000003", "l": "positive regulation of DNA damage checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0062125", "l": "regulation of mitochondrial gene expression", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050902", "l": "leukocyte adhesive activation", "d": ["The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901692", "l": "regulation of compound eye retinal cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903883", "l": "positive regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006524", "l": "alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903432", "l": "regulation of TORC1 signaling", "d": ["Any process that modulates the frequency, rate or extent of TORC1 signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052647", "l": "pentitol phosphate metabolic process", "d": ["The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048341", "l": "paraxial mesoderm formation", "d": ["The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901230", "l": "negative regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097264", "l": "self proteolysis", "d": ["The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021610", "l": "facial nerve morphogenesis", "d": ["The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032621", "l": "interleukin-18 production", "d": ["The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003322", "l": "pancreatic A cell development", "d": ["The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046683", "l": "response to organophosphorus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042161", "l": "lipoprotein oxidation", "d": ["The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061207", "l": "mesonephric juxtaglomerulus cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032185", "l": "septin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072734", "l": "cellular response to staurosporine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035469", "l": "determination of pancreatic left/right asymmetry", "d": ["Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070394", "l": "lipoteichoic acid metabolic process", "d": ["The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901995", "l": "positive regulation of meiotic cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070489", "l": "T cell aggregation", "d": ["The adhesion of one T cell to one or more other T cells via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0016102", "l": "diterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902697", "l": "valine catabolic process to isobutanol", "d": ["The chemical reactions and pathways resulting in the breakdown of valine to isobutanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0008277", "l": "regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035139", "l": "pelvic fin morphogenesis", "d": ["The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003398", "l": "glial cell differentiation involved in amphid sensory organ development", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0016119", "l": "carotene metabolic process", "d": ["The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051220", "l": "cytoplasmic sequestering of protein", "d": ["The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903606", "l": "cytochrome c metabolic process", "d": ["The chemical reactions and pathways involving cytochrome c."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033321", "l": "homomethionine metabolic process", "d": ["The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021555", "l": "midbrain-hindbrain boundary morphogenesis", "d": ["The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903599", "l": "positive regulation of autophagy of mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0031106", "l": "septin ring organization", "d": ["Control of the formation, spatial distribution, and breakdown of the septin ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001110", "l": "RNA polymerase III promoter clearance", "d": ["A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000374", "l": "regulation of oxygen metabolic process", "d": ["Any process that modulates the frequency, rate or extent of oxygen metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904147", "l": "response to nonylphenol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000447", "l": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071549", "l": "cellular response to dexamethasone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000993", "l": "positive regulation of galactomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060022", "l": "hard palate development", "d": ["The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0048444", "l": "floral organ morphogenesis", "d": ["The process in which the anatomical structures of the floral organ are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019576", "l": "aerobic fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0006414", "l": "translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0006000", "l": "fructose metabolic process", "d": ["The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000992", "l": "negative regulation of galactomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006958", "l": "complement activation, classical pathway", "d": ["Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097326", "l": "melanocyte adhesion", "d": ["The attachment of a melanocyte to another cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:2000278", "l": "regulation of DNA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of DNA biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060301", "l": "positive regulation of cytokine activity", "d": ["Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0101010", "l": "pulmonary blood vessel remodeling", "d": ["The reorganization or renovation of existing pulmonary blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050829", "l": "defense response to Gram-negative bacterium", "d": ["Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0022011", "l": "myelination in peripheral nervous system", "d": ["The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001292", "l": "codeine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042666", "l": "negative regulation of ectodermal cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007539", "l": "primary sex determination, soma", "d": ["The transmission of information about sexual status from the initial, general, determination to signals specific to the soma."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071043", "l": "CUT metabolic process", "d": ["The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018953", "l": "p-cymene metabolic process", "d": ["The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009263", "l": "deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140058", "l": "neuron projection arborization", "d": ["The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090709", "l": "regulation of timing of plant organ formation", "d": ["Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000417", "l": "negative regulation of eosinophil migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0048639", "l": "positive regulation of developmental growth", "d": ["Any process that activates, maintains or increases the rate of developmental growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2001026", "l": "regulation of endothelial cell chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097616", "l": "positive regulation by host of symbiont type IV pilus-dependent motility", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0086015", "l": "SA node cell action potential", "d": ["An action potential that occurs in a sinoatrial node cardiac muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905035", "l": "negative regulation of antifungal innate immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000252", "l": "negative regulation of feeding behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046043", "l": "TDP metabolic process", "d": ["The chemical reactions and pathways involving TDP, ribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990705", "l": "cholangiocyte proliferation", "d": ["The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009692", "l": "ethylene metabolic process", "d": ["The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901396", "l": "negative regulation of transforming growth factor beta2 activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035943", "l": "estrone secretion", "d": ["The regulated release of estrone into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019231", "l": "perception of static position", "d": ["The perception of the orientation of different parts of the body with respect to one another."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061445", "l": "endocardial cushion cell fate commitment", "d": ["The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021501", "l": "prechordal plate formation", "d": ["The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.344397115515811", "identifiers": [{"i": "GO:0010556", "l": "regulation of macromolecule biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0017006", "l": "protein-tetrapyrrole linkage", "d": ["The covalent linking of a tetrapyrrole to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060099", "l": "regulation of phagocytosis, engulfment", "d": ["Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902472", "l": "regulation of mitotic cytokinesis, division site positioning", "d": ["Any process that modulates the frequency, rate or extent of mitotic cytokinesis, division site positioning."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070946", "l": "neutrophil-mediated killing of gram-positive bacterium", "d": ["The directed killing of a gram-positive bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000887", "l": "glucuronoarabinoxylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904366", "l": "negative regulation of chemokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046054", "l": "dGMP metabolic process", "d": ["The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140199", "l": "negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990115", "l": "RNA polymerase III assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048632", "l": "negative regulation of skeletal muscle tissue growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904952", "l": "hydroxycinnamic acid transport", "d": ["The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043032", "l": "positive regulation of macrophage activation", "d": ["Any process that stimulates, induces or increases the rate of macrophage activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060653", "l": "epithelial cell differentiation involved in mammary gland cord morphogenesis", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033068", "l": "macrolide biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0072414", "l": "response to mitotic cell cycle checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010384", "l": "cell wall proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001698", "l": "gastrin-induced gastric acid secretion", "d": ["The regulated release of gastric acid induced by the interaction of gastrin with its receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903832", "l": "regulation of cellular response to amino acid starvation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018295", "l": "protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine", "d": ["The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046431", "l": "(R)-4-hydroxymandelate metabolic process", "d": ["The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905014", "l": "positive regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043517", "l": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0000741", "l": "karyogamy", "d": ["The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904885", "l": "beta-catenin destruction complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046710", "l": "GDP metabolic process", "d": ["The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:2000142", "l": "regulation of DNA-templated transcription initiation", "d": ["Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060645", "l": "peripheral mammary gland bud epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098823", "l": "peptidyl-cysteine modification to S-amindino-L-cysteine", "d": ["The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0032377", "l": "regulation of intracellular lipid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000406", "l": "positive regulation of T cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of T cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061163", "l": "endoplasmic reticulum polarization", "d": ["The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090602", "l": "sieve element enucleation", "d": ["The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075070", "l": "adhesion of symbiont hyphopodium to host", "d": ["The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901923", "l": "negative regulation of sclerotium development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904444", "l": "regulation of establishment of Sertoli cell barrier", "d": ["Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061755", "l": "positive regulation of circulating fibrinogen levels", "d": ["Any process that increases the quantity of fibrinogen circulating in the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0072659", "l": "protein localization to plasma membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052001", "l": "adhesion to host cell via type IV pili", "d": ["Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046724", "l": "oxalic acid secretion", "d": ["The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009238", "l": "enterobactin metabolic process", "d": ["The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110161", "l": "positive regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034031", "l": "ribonucleoside bisphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042243", "l": "asexual spore wall assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099093", "l": "calcium export from the mitochondrion", "d": ["A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033469", "l": "gibberellin 12 metabolic process", "d": ["The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990946", "l": "meiosis I/meiosis II transition", "d": ["The cell cycle process in which a cell progresses from meiosis I to meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060974", "l": "cell migration involved in heart formation", "d": ["The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009140", "l": "pyrimidine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071711", "l": "basement membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000614", "l": "positive regulation of thyroid-stimulating hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075221", "l": "negative regulation of zoospore encystment on host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0046885", "l": "regulation of hormone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000301", "l": "negative regulation of synaptic vesicle exocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002159", "l": "desmosome assembly", "d": ["A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006735", "l": "NADH regeneration", "d": ["A metabolic process that generates a pool of NADH by the reduction of NAD+."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071273", "l": "morphine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0021877", "l": "forebrain neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060720", "l": "spongiotrophoblast cell proliferation", "d": ["The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000295", "l": "regulation of hydrogen peroxide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097503", "l": "sialylation", "d": ["The covalent attachment of sialic acid to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070754", "l": "regulation of interleukin-35 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-35 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097391", "l": "chemokine (C-X-C motif) ligand 13 production", "d": ["The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0042471", "l": "ear morphogenesis", "d": ["The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042219", "l": "cellular modified amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002271", "l": "plasmacytoid dendritic cell activation involved in immune response", "d": ["A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0052040", "l": "modulation by symbiont of host programmed cell death", "d": ["Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0000422", "l": "autophagy of mitochondrion", "d": ["The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900892", "l": "positive regulation of pentadecane metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031580", "l": "membrane raft distribution", "d": ["The process that establishes the spatial arrangement of membrane rafts within a cellular membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042487", "l": "regulation of odontogenesis of dentin-containing tooth", "d": ["Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050732", "l": "negative regulation of peptidyl-tyrosine phosphorylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035499", "l": "carnosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060033", "l": "anatomical structure regression", "d": ["The developmental process in which an anatomical stucture is destroyed as a part of its normal progression."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000850", "l": "negative regulation of glucocorticoid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061069", "l": "male urethra development", "d": ["The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033359", "l": "lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006254", "l": "CTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048769", "l": "sarcomerogenesis", "d": ["The process in which sarcomeres are added in series within a fiber."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019242", "l": "methylglyoxal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044759", "l": "negative regulation by symbiont of host synaptic transmission", "d": ["Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001795", "l": "type IIb hypersensitivity", "d": ["An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042480", "l": "negative regulation of eye photoreceptor cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090269", "l": "fibroblast growth factor production", "d": ["The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003230", "l": "cardiac atrium development", "d": ["The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0003062", "l": "regulation of heart rate by chemical signal", "d": ["The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990953", "l": "intramanchette transport", "d": ["The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010777", "l": "meiotic mismatch repair involved in reciprocal meiotic recombination", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031952", "l": "regulation of protein autophosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072647", "l": "interferon-epsilon production", "d": ["The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990113", "l": "RNA polymerase I assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "46.632465937736391", "identifiers": [{"i": "GO:0006952", "l": "defense response", "d": ["Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019498", "l": "n-octane oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150069", "l": "negative regulation of tubulin deacetylase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015899", "l": "aminotriazole transport", "d": ["The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0042327", "l": "positive regulation of phosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0009262", "l": "deoxyribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0046513", "l": "ceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032820", "l": "regulation of natural killer cell proliferation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018177", "l": "protein uridylylation", "d": ["The addition of phospho-uridine to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905935", "l": "positive regulation of cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072263", "l": "metanephric intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:1902806", "l": "regulation of cell cycle G1/S phase transition", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990091", "l": "sodium-dependent self proteolysis", "d": ["The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060647", "l": "mesenchymal cell condensation involved in mammary fat development", "d": ["The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900243", "l": "negative regulation of synaptic vesicle endocytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090214", "l": "spongiotrophoblast layer developmental growth", "d": ["The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0030301", "l": "cholesterol transport", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900957", "l": "negative regulation of 17-methylnonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016325", "l": "oocyte microtubule cytoskeleton organization", "d": ["Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.632625170261541", "identifiers": [{"i": "GO:0046942", "l": "carboxylic acid transport", "d": ["The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000913", "l": "negative regulation of galactoglucomannan catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0030243", "l": "cellulose metabolic process", "d": ["The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018109", "l": "peptidyl-arginine phosphorylation", "d": ["The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035831", "l": "palmatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900948", "l": "negative regulation of isoprene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.310881285254894", "identifiers": [{"i": "GO:0009894", "l": "regulation of catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021888", "l": "hypothalamus gonadotrophin-releasing hormone neuron development", "d": ["The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000572", "l": "positive regulation of interleukin-4-dependent isotype switching to IgE isotypes", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0045620", "l": "negative regulation of lymphocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0051145", "l": "smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0002544", "l": "chronic inflammatory response", "d": ["Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051444", "l": "negative regulation of ubiquitin-protein transferase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901392", "l": "regulation of transforming growth factor beta1 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044030", "l": "regulation of DNA methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043693", "l": "monoterpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900570", "l": "diorcinol metabolic process", "d": ["The chemical reactions and pathways involving diorcinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003371", "l": "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903070", "l": "negative regulation of ER-associated ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006647", "l": "phosphatidyl-N-monomethylethanolamine biosynthetic process", "d": ["The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140745", "l": "siRNA transcription", "d": ["The transcription of a small interfering RNA from an RNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061613", "l": "glycolytic process from glycerol", "d": ["The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900934", "l": "positive regulation of nonadec-1-ene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0089709", "l": "L-histidine transmembrane transport", "d": ["The directed movement of L-histidine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0032835", "l": "glomerulus development", "d": ["The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901358", "l": "beta-D-galactofuranose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050993", "l": "dimethylallyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving dimethylallyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051523", "l": "cell growth mode switching, monopolar to bipolar", "d": ["The process in which a cell switches from monopolar cell growth to bipolar cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061622", "l": "glycolytic process through glucose-1-phosphate", "d": ["The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035092", "l": "sperm DNA condensation", "d": ["The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042199", "l": "cyanuric acid metabolic process", "d": ["The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900973", "l": "positive regulation of sarcinapterin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902329", "l": "bacterial-type DNA replication termination", "d": ["Any DNA replication termination that is involved in bacterial-type DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045221", "l": "negative regulation of FasL production", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090375", "l": "negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060289", "l": "compartment boundary maintenance", "d": ["A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901943", "l": "(+)-epi-alpha-bisabolol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034441", "l": "plasma lipoprotein particle oxidation", "d": ["The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052649", "l": "coenzyme gamma-F420-2 metabolic process", "d": ["The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000679", "l": "positive regulation of transcription regulatory region DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032064", "l": "positive regulation of translational initiation in response to osmotic stress", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.326385679795735", "identifiers": [{"i": "GO:0007051", "l": "spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901506", "l": "regulation of acylglycerol transport", "d": ["Any process that modulates the frequency, rate or extent of acylglycerol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019234", "l": "sensory perception of fast pain", "d": ["The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042150", "l": "plasmid recombination", "d": ["A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060461", "l": "right lung morphogenesis", "d": ["The process in which anatomical structures of the right lung are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0009561", "l": "megagametogenesis", "d": ["The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903710", "l": "spermine transmembrane transport", "d": ["The process in which spermine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904491", "l": "protein localization to ciliary transition zone", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070575", "l": "peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation", "d": ["The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009174", "l": "pyrimidine ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0034656", "l": "nucleobase-containing small molecule catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044396", "l": "actin cortical patch organization", "d": ["A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000984", "l": "negative regulation of ATP citrate synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0007202", "l": "activation of phospholipase C activity", "d": ["The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048733", "l": "sebaceous gland development", "d": ["The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060097", "l": "cytoskeletal rearrangement involved in phagocytosis, engulfment", "d": ["The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000948", "l": "amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071406", "l": "cellular response to methylmercury", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006794", "l": "phosphorus utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003091", "l": "renal water homeostasis", "d": ["Renal process involved in the maintenance of an internal steady state of water in the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042938", "l": "dipeptide transport", "d": ["The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902523", "l": "positive regulation of protein K63-linked ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903581", "l": "regulation of basophil degranulation", "d": ["Any process that modulates the frequency, rate or extent of basophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.615557865864595", "identifiers": [{"i": "GO:0099643", "l": "signal release from synapse", "d": ["Any signal release from a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045876", "l": "positive regulation of sister chromatid cohesion", "d": ["Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0044342", "l": "type B pancreatic cell proliferation", "d": ["The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032768", "l": "regulation of monooxygenase activity", "d": ["Any process that modulates the activity of a monooxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048351", "l": "negative regulation of paraxial mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0044718", "l": "siderophore transmembrane transport", "d": ["The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051280", "l": "negative regulation of release of sequestered calcium ion into cytosol", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016242", "l": "negative regulation of macroautophagy", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:2000027", "l": "regulation of animal organ morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of animal organ morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030038", "l": "contractile actin filament bundle assembly", "d": ["Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120138", "l": "regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014730", "l": "skeletal muscle regeneration at neuromuscular junction", "d": ["The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009452", "l": "7-methylguanosine RNA capping", "d": ["The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990029", "l": "vasomotion", "d": ["The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905530", "l": "negative regulation of uracil import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0071322", "l": "cellular response to carbohydrate stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010895", "l": "negative regulation of ergosterol biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1903020", "l": "positive regulation of glycoprotein metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009450", "l": "gamma-aminobutyric acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048614", "l": "post-embryonic ectodermal digestive tract morphogenesis", "d": ["The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014736", "l": "negative regulation of muscle atrophy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045813", "l": "positive regulation of Wnt signaling pathway, calcium modulating pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009224", "l": "CMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018188", "l": "peptidyl-proline di-hydroxylation", "d": ["The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019656", "l": "glucose catabolic process to D-lactate and ethanol", "d": ["The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002076", "l": "osteoblast development", "d": ["The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0031507", "l": "heterochromatin formation", "d": ["An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0141076", "l": "symbiont-mediated suppression of host TRAF-mediated signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a TRAF-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019857", "l": "5-methylcytosine metabolic process", "d": ["The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006039", "l": "cell wall chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106434", "l": "retinal isomerization", "d": ["The reactions involved in isomerization of all trans to all cis retnal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903932", "l": "regulation of DNA primase activity", "d": ["Any process that modulates the frequency, rate or extent of DNA primase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090629", "l": "lagging strand initiation", "d": ["The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021927", "l": "deep nuclear neuron precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006615", "l": "SRP-dependent cotranslational protein targeting to membrane, docking", "d": ["The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019345", "l": "cysteine biosynthetic process via S-sulfo-L-cysteine", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001294", "l": "malonyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905443", "l": "regulation of clathrin coat assembly", "d": ["Any process that modulates the frequency, rate or extent of clathrin coat assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016077", "l": "sno(s)RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0000820", "l": "regulation of glutamine family amino acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048260", "l": "positive regulation of receptor-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061304", "l": "retinal blood vessel morphogenesis", "d": ["The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900153", "l": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0006817", "l": "phosphate ion transport", "d": ["The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0033047", "l": "regulation of mitotic sister chromatid segregation", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061299", "l": "retina vasculature morphogenesis in camera-type eye", "d": ["The process in which the vasculature of the retina is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903698", "l": "positive regulation of microvillus assembly", "d": ["Any process that activates or increases the frequency, rate or extent of microvillus assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045782", "l": "positive regulation of cell budding", "d": ["Any process that activates or increases the frequency, rate or extent of cell budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006017", "l": "deoxyribose 1,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0007252", "l": "I-kappaB phosphorylation", "d": ["The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009646", "l": "response to absence of light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006549", "l": "isoleucine metabolic process", "d": ["The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901754", "l": "vitamin D3 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vitamin D3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905856", "l": "negative regulation of pentose-phosphate shunt", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0031280", "l": "negative regulation of cyclase activity", "d": ["Any process that stops or reduces the activity of a cyclase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120011", "l": "intermembrane sterol transfer", "d": ["The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.505740659167984", "identifiers": [{"i": "GO:0006066", "l": "alcohol metabolic process", "d": ["The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006273", "l": "lagging strand elongation", "d": ["The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0030100", "l": "regulation of endocytosis", "d": ["Any process that modulates the frequency, rate or extent of endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1900429", "l": "negative regulation of filamentous growth of a population of unicellular organisms", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002884", "l": "negative regulation of hypersensitivity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009401", "l": "phosphoenolpyruvate-dependent sugar phosphotransferase system", "d": ["The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046278", "l": "3,4-dihydroxybenzoate metabolic process", "d": ["The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901844", "l": "regulation of cell communication by electrical coupling involved in cardiac conduction", "d": ["Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140636", "l": "copper import into the mitochondrion", "d": ["The process in which copper is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033466", "l": "trans-zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045776", "l": "negative regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is decreased."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.681872163386743", "identifiers": [{"i": "GO:0071417", "l": "cellular response to organonitrogen compound", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015988", "l": "energy coupled proton transmembrane transport, against electrochemical gradient", "d": ["The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110160", "l": "negative regulation of mitotic spindle formation (spindle phase one)", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903608", "l": "protein localization to cytoplasmic stress granule", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002727", "l": "regulation of natural killer cell cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905685", "l": "negative regulation of plasma membrane repair", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140290", "l": "peptidyl-serine ADP-deribosylation", "d": ["The removal of ADP-ribose from ADP-ribosylserine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900137", "l": "negative regulation of chemokine activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902985", "l": "mitotic pre-replicative complex assembly", "d": ["Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035170", "l": "lymph gland crystal cell differentiation", "d": ["The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900752", "l": "malonic acid transport", "d": ["The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000178", "l": "negative regulation of neural precursor cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034405", "l": "response to fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045113", "l": "regulation of integrin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045589", "l": "regulation of regulatory T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901807", "l": "capsanthin metabolic process", "d": ["The chemical reactions and pathways involving capsanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000265", "l": "positive regulation of blood coagulation, extrinsic pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071309", "l": "cellular response to phylloquinone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000965", "l": "positive regulation of cellooligosaccharide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018116", "l": "peptidyl-lysine adenylylation", "d": ["The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0002515", "l": "B cell anergy", "d": ["Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032345", "l": "negative regulation of aldosterone metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046706", "l": "CDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097551", "l": "mitochondrial double-strand break repair", "d": ["The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031632", "l": "positive regulation of synaptic vesicle fusion to presynaptic active zone membrane", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000230", "l": "negative regulation of pancreatic stellate cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0007315", "l": "pole plasm assembly", "d": ["Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000431", "l": "regulation of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033051", "l": "aminophosphonate metabolic process", "d": ["The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071245", "l": "cellular response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.720637850670617", "identifiers": [{"i": "GO:1901566", "l": "organonitrogen compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of organonitrogen compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904906", "l": "positive regulation of endothelial cell-matrix adhesion via fibronectin", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035122", "l": "embryonic medial fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050685", "l": "positive regulation of mRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021538", "l": "epithalamus development", "d": ["The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0044145", "l": "modulation of formation of structure involved in a symbiotic process", "d": ["Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903744", "l": "positive regulation of anterograde synaptic vesicle transport", "d": ["Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000302", "l": "positive regulation of synaptic vesicle exocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043103", "l": "hypoxanthine salvage", "d": ["Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010548", "l": "regulation of thylakoid membrane disassembly", "d": ["Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051309", "l": "female meiosis chromosome separation", "d": ["The process in which paired chromosomes are physically detached from each other during female meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071264", "l": "positive regulation of translational initiation in response to starvation", "d": ["Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060437", "l": "lung growth", "d": ["The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0002065", "l": "columnar/cuboidal epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045841", "l": "negative regulation of mitotic metaphase/anaphase transition", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048308", "l": "organelle inheritance", "d": ["The partitioning of organelles between daughter cells at cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080185", "l": "effector-mediated induction of plant hypersensitive response by symbiont", "d": ["A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1905421", "l": "regulation of plant organ morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of plant organ morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070564", "l": "positive regulation of vitamin D receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110164", "l": "positive regulation of mitotic spindle elongation (spindle phase three)", "d": ["Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051210", "l": "isotropic cell growth", "d": ["The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033076", "l": "isoquinoline alkaloid metabolic process", "d": ["The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060633", "l": "negative regulation of transcription initiation by RNA polymerase II", "d": ["Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019423", "l": "sulfur oxidation, ferric ion-dependent", "d": ["A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044618", "l": "modulation of relaxation of uterine smooth muscle in another organism", "d": ["The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901803", "l": "1,5-anhydro-D-fructose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0009847", "l": "spore germination", "d": ["The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008071", "l": "maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded", "d": ["Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035069", "l": "larval midgut histolysis", "d": ["The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0000128", "l": "flocculation", "d": ["The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0030436", "l": "asexual sporulation", "d": ["The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0043970", "l": "histone H3-K9 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071977", "l": "bacterial-type flagellum-dependent swimming motility", "d": ["Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006516", "l": "glycoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075510", "l": "macropinocytosis involved in viral entry into host cell", "d": ["Any macropinocytosis that is involved in the uptake of a virus into a host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009992", "l": "intracellular water homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of water within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990798", "l": "pancreas regeneration", "d": ["The regrowth of a destroyed pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010746", "l": "regulation of long-chain fatty acid import across plasma membrane", "d": ["Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032375", "l": "negative regulation of cholesterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033194", "l": "response to hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019262", "l": "N-acetylneuraminate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0008228", "l": "opsonization", "d": ["The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0080184", "l": "response to phenylpropanoid", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000423", "l": "negative regulation of eosinophil chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.014669355571556", "identifiers": [{"i": "GO:0009636", "l": "response to toxic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000461", "l": "endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0006352", "l": "DNA-templated transcription initiation", "d": ["The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0022611", "l": "dormancy process", "d": ["A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902565", "l": "positive regulation of neutrophil activation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.653168928076894", "identifiers": [{"i": "GO:0048469", "l": "cell maturation", "d": ["The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097107", "l": "postsynaptic density assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901838", "l": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "d": ["Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061095", "l": "positive regulation of turning behavior involved in mating", "d": ["Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001225", "l": "regulation of chloride transport", "d": ["Any process that modulates the frequency, rate or extent of chloride transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048339", "l": "paraxial mesoderm development", "d": ["The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033531", "l": "stachyose metabolic process", "d": ["The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905032", "l": "negative regulation of membrane repolarization during cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901727", "l": "positive regulation of histone deacetylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of histone deacetylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.265635824335227", "identifiers": [{"i": "GO:0046394", "l": "carboxylic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900113", "l": "negative regulation of histone H3-K9 trimethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002290", "l": "gamma-delta T cell activation involved in immune response", "d": ["The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090340", "l": "positive regulation of secretion of lysosomal enzymes", "d": ["Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048268", "l": "clathrin coat assembly", "d": ["The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033370", "l": "maintenance of protein location in mast cell secretory granule", "d": ["A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072161", "l": "mesenchymal cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002569", "l": "somatic diversification of immune receptors by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061869", "l": "regulation of hepatic stellate cell migration", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042631", "l": "cellular response to water deprivation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902393", "l": "negative regulation of exodeoxyribonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0075215", "l": "modulation of spore encystment on host", "d": ["Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901282", "l": "fructoselysine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructoselysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0031167", "l": "rRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042190", "l": "vanillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990466", "l": "protein autosumoylation", "d": ["The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.594400196502249", "identifiers": [{"i": "GO:0120255", "l": "olefinic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000433", "l": "positive regulation of cytokinesis, actomyosin contractile ring assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0098763", "l": "mitotic cell cycle phase", "d": ["One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035333", "l": "Notch receptor processing, ligand-dependent", "d": ["The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902655", "l": "aromatic primary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic primary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035225", "l": "determination of genital disc primordium", "d": ["Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1902262", "l": "apoptotic process involved in blood vessel morphogenesis", "d": ["Any apoptotic process that is involved in blood vessel morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000105", "l": "positive regulation of DNA-templated DNA replication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032908", "l": "regulation of transforming growth factor beta1 production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.020961935443736", "identifiers": [{"i": "GO:0010629", "l": "negative regulation of gene expression", "d": ["Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010040", "l": "response to iron(II) ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002850", "l": "negative regulation of peripheral T cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0046887", "l": "positive regulation of hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904919", "l": "transmembrane L-cystine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000253", "l": "positive regulation of feeding behavior", "d": ["Any process that activates or increases the frequency, rate or extent of feeding behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032815", "l": "negative regulation of natural killer cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021600", "l": "abducens nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098940", "l": "anterograde trans-synaptic signaling by nitric oxide", "d": ["Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043247", "l": "telomere maintenance in response to DNA damage", "d": ["Any process that occur in response to the presence of critically short or damaged telomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0010770", "l": "positive regulation of cell morphogenesis", "d": ["Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902012", "l": "poly(ribitol phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098970", "l": "postsynaptic neurotransmitter receptor diffusion trapping", "d": ["The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900833", "l": "D-leucine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070998", "l": "sensory perception of gravity", "d": ["The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120070", "l": "negative regulation of stomach fundus smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072046", "l": "establishment of planar polarity involved in nephron morphogenesis", "d": ["Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061889", "l": "negative regulation of astrocyte activation", "d": ["Any process that decreases the frequency, rate or extent of astrocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.6720795298599", "identifiers": [{"i": "GO:0009725", "l": "response to hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0050995", "l": "negative regulation of lipid catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072222", "l": "metanephric early distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.769355763942954", "identifiers": [{"i": "GO:0061005", "l": "cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051356", "l": "visual perception involved in equilibrioception", "d": ["The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061837", "l": "neuropeptide processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070400", "l": "teichoic acid D-alanylation", "d": ["The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021916", "l": "inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors", "d": ["Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007036", "l": "vacuolar calcium ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009909", "l": "regulation of flower development", "d": ["Any process that modulates the frequency, rate or extent of flower development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007414", "l": "axonal defasciculation", "d": ["Separation of axons away from a bundle of axons known as a fascicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042840", "l": "D-glucuronate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000008", "l": "regulation of protein localization to cell surface", "d": ["Any process that modulates the frequency, rate or extent of protein localization to the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905784", "l": "regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140209", "l": "zinc ion import into endoplasmic reticulum", "d": ["The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048741", "l": "skeletal muscle fiber development", "d": ["The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901780", "l": "pentalenolactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentalenolactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.697875049310156", "identifiers": [{"i": "GO:0032103", "l": "positive regulation of response to external stimulus", "d": ["Any process that activates, maintains or increases the rate of a response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032671", "l": "regulation of interleukin-27 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-27 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904673", "l": "negative regulation of somatic stem cell population maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120229", "l": "protein localization to motile cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a motile cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0002249", "l": "lymphocyte anergy", "d": ["Any process contributing to lymphocyte anergy, a state of functional inactivation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904677", "l": "positive regulation of somatic stem cell division", "d": ["Any process that activates or increases the frequency, rate or extent of somatic stem cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0007442", "l": "hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1903170", "l": "negative regulation of calcium ion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046083", "l": "adenine metabolic process", "d": ["The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060211", "l": "regulation of nuclear-transcribed mRNA poly(A) tail shortening", "d": ["Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905869", "l": "negative regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042726", "l": "flavin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043708", "l": "cell adhesion involved in biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034982", "l": "mitochondrial protein processing", "d": ["The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014882", "l": "regulation of myofibril number", "d": ["Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032208", "l": "negative regulation of telomere maintenance via recombination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007546", "l": "somatic processes downstream of sex determination signal", "d": ["The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009200", "l": "deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000956", "l": "positive regulation of cyclodextrin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0016441", "l": "post-transcriptional gene silencing", "d": ["The inactivation of gene expression that occurs after transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0039020", "l": "pronephric nephron tubule development", "d": ["The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900343", "l": "negative regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097446", "l": "protein localization to eisosome filament", "d": ["A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900716", "l": "regulation of violaceol II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015971", "l": "guanosine tetraphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015911", "l": "long-chain fatty acid import across plasma membrane", "d": ["The directed movement of a long-chain fatty acid from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048081", "l": "positive regulation of cuticle pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904248", "l": "regulation of age-related resistance", "d": ["Any process that modulates the extent of age-related resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042532", "l": "negative regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021706", "l": "locus ceruleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032828", "l": "positive regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1904396", "l": "regulation of neuromuscular junction development", "d": ["Any process that modulates the frequency, rate or extent of neuromuscular junction development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902355", "l": "endothelial tube lumen extension involved in blood vessel lumen ensheathment", "d": ["Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062195", "l": "microtubule bundle maintenance", "d": ["The organization process that preserves a microtubule bundle in a stable functional or structural state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990213", "l": "negative regulation by symbiont of salicylic acid levels in host", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902250", "l": "regulation of erythrocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010618", "l": "aerenchyma formation", "d": ["The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0007595", "l": "lactation", "d": ["The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070143", "l": "mitochondrial alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042374", "l": "phylloquinone metabolic process", "d": ["The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006013", "l": "mannose metabolic process", "d": ["The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042638", "l": "exogen", "d": ["The shedding phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904374", "l": "cellular response to kainic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905743", "l": "calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration", "d": ["Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043466", "l": "pyrimidine nucleobase fermentation", "d": ["The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904228", "l": "positive regulation of glycogen synthase activity, transferring glucose-1-phosphate", "d": ["Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901090", "l": "regulation of protein tetramerization", "d": ["Any process that modulates the frequency, rate or extent of protein tetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0140527", "l": "reciprocal homologous recombination", "d": ["A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0014013", "l": "regulation of gliogenesis", "d": ["Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903570", "l": "regulation of protein kinase D signaling", "d": ["Any process that modulates the frequency, rate or extent of protein kinase D signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060978", "l": "angiogenesis involved in coronary vascular morphogenesis", "d": ["Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061377", "l": "mammary gland lobule development", "d": ["The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905017", "l": "positive regulation of isoleucine-tRNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0046718", "l": "viral entry into host cell", "d": ["The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033332", "l": "ent-kaurene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ent-kaurene. 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Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902867", "l": "negative regulation of retina development in camera-type eye", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0090151", "l": "establishment of protein localization to mitochondrial membrane", "d": ["The directed movement of a protein to a specific location in the mitochondrial membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044497", "l": "positive regulation of blood pressure in another organism", "d": ["A process by which one organism increases the force with which blood travels through the circulatory system of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006246", "l": "dTDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010925", "l": "positive regulation of inositol-polyphosphate 5-phosphatase activity", "d": ["Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021803", "l": "extension of leading cell process to pial surface", "d": ["The extension of a long process to the pial surface as a cell leaves the ventricular zone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901082", "l": "positive regulation of relaxation of smooth muscle", "d": ["Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902238", "l": "regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060334", "l": "regulation of type II interferon-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019588", "l": "anaerobic glycerol catabolic process", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034772", "l": "histone H4-K20 dimethylation", "d": ["The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032876", "l": "negative regulation of DNA endoreduplication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046249", "l": "alpha-pinene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090299", "l": "regulation of neural crest formation", "d": ["Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900707", "l": "regulation of tensidol A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0048738", "l": "cardiac muscle tissue development", "d": ["The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000554", "l": "regulation of T-helper 1 cell cytokine production", "d": ["Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099006", "l": "viral entry via permeabilization of endosomal membrane", "d": ["The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072180", "l": "mesonephric duct morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009998", "l": "negative regulation of retinal cone cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0033301", "l": "cell cycle comprising mitosis without cytokinesis", "d": ["A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002586", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072054", "l": "renal outer medulla development", "d": ["The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098045", "l": "virus baseplate assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus baseplate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900589", "l": "violaceol I catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of violaceol I."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097201", "l": "negative regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905221", "l": "positive regulation of platelet formation", "d": ["Any process that activates or increases the frequency, rate or extent of platelet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042297", "l": "vocal learning", "d": ["A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903971", "l": "positive regulation of response to macrophage colony-stimulating factor", "d": ["Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010622", "l": "specification of ovule identity", "d": ["The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090714", "l": "innate immunity memory response", "d": ["An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0048438", "l": "floral whorl development", "d": ["The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070070", "l": "proton-transporting V-type ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070641", "l": "vitamin D4 metabolic process", "d": ["The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006309", "l": "apoptotic DNA fragmentation", "d": ["The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000336", "l": "negative regulation of endothelial microparticle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071678", "l": "olfactory bulb axon guidance", "d": ["The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0019094", "l": "pole plasm mRNA localization", "d": ["Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031954", "l": "positive regulation of protein autophosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900890", "l": "regulation of pentadecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of pentadecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042691", "l": "positive regulation of crystal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of crystal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900825", "l": "regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032573", "l": "response to phylloquinone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0051418", "l": "microtubule nucleation by microtubule organizing center", "d": ["The 'de novo' formation of a microtubule, mediated by the microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902521", "l": "response to etoposide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046762", "l": "viral budding from endoplasmic reticulum membrane", "d": ["A viral budding that starts with formation of a membrane curvature in the host ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061581", "l": "corneal epithelial cell migration", "d": ["The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018173", "l": "peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060550", "l": "positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "d": ["Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904419", "l": "negative regulation of telomeric loop formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051559", "l": "phlobaphene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097628", "l": "distal tip cell migration", "d": ["The orderly movement of a distal tip cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010157", "l": "response to chlorate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035223", "l": "leg disc pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation in the leg imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061162", "l": "establishment of monopolar cell polarity", "d": ["The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071503", "l": "response to heparin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046487", "l": "glyoxylate metabolic process", "d": ["The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0002707", "l": "negative regulation of lymphocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0023022", "l": "termination of T cell signal transduction", "d": ["The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0005992", "l": "trehalose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006919", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904860", "l": "DNA synthesis involved in mitotic DNA replication", "d": ["Any DNA biosynthetic process that is involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000293", "l": "negative regulation of defecation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defecation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060311", "l": "negative regulation of elastin catabolic process", "d": ["Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036453", "l": "transitive RNA interference", "d": ["An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030632", "l": "D-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060764", "l": "cell-cell signaling involved in mammary gland development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021591", "l": "ventricular system development", "d": ["The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905699", "l": "regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033615", "l": "mitochondrial proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019533", "l": "cellobiose transport", "d": ["The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1900620", "l": "acetate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007462", "l": "R1/R6 cell fate commitment", "d": ["The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901300", "l": "positive regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0034614", "l": "cellular response to reactive oxygen species", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048574", "l": "long-day photoperiodism, flowering", "d": ["A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060785", "l": "regulation of apoptosis involved in tissue homeostasis", "d": ["Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048460", "l": "flower formation", "d": ["The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009443", "l": "pyridoxal 5'-phosphate salvage", "d": ["Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019854", "l": "L-ascorbic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072677", "l": "eosinophil migration", "d": ["The movement of an eosinophil within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006597", "l": "spermine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006857", "l": "oligopeptide transport", "d": ["The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019716", "l": "N-terminal peptidyl-alanine monomethylation", "d": ["The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141026", "l": "adhesion of symbiont to host cell surface via host membrane cholesterol", "d": ["The attachment of a symbiont to its host by binding to cholesterol on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0045601", "l": "regulation of endothelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072203", "l": "cell proliferation involved in metanephros development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.710521892834109", "identifiers": [{"i": "GO:0071887", "l": "leukocyte apoptotic process", "d": ["Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.170119586754993", "identifiers": [{"i": "GO:0007052", "l": "mitotic spindle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901626", "l": "regulation of postsynaptic membrane organization", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902873", "l": "negative regulation of horizontal cell localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045636", "l": "positive regulation of melanocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002032", "l": "desensitization of G protein-coupled receptor signaling pathway by arrestin", "d": ["The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008052", "l": "sensory organ boundary specification", "d": ["The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001870", "l": "positive regulation of complement activation, lectin pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072108", "l": "positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900932", "l": "regulation of nonadec-1-ene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034159", "l": "regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071324", "l": "cellular response to disaccharide stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048557", "l": "embryonic digestive tract morphogenesis", "d": ["The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036273", "l": "response to statin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002315", "l": "marginal zone B cell differentiation", "d": ["The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900452", "l": "regulation of long-term synaptic depression", "d": ["Any process that modulates the frequency, rate or extent of long term synaptic depression."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0032944", "l": "regulation of mononuclear cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mononuclear cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002827", "l": "positive regulation of T-helper 1 type immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0006144", "l": "purine nucleobase metabolic process", "d": ["The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070676", "l": "intralumenal vesicle formation", "d": ["The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903579", "l": "negative regulation of ATP metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010323", "l": "negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905246", "l": "negative regulation of aspartic-type peptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019589", "l": "anaerobic glycerol catabolic process to propane-1,3-diol", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039536", "l": "negative regulation of RIG-I signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032525", "l": "somite rostral/caudal axis specification", "d": ["The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0051924", "l": "regulation of calcium ion transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090357", "l": "regulation of tryptophan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990771", "l": "clathrin-dependent extracellular exosome endocytosis", "d": ["The clathrin-mediated endocytosis of an extracellular exosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900310", "l": "negative regulation of maltoheptaose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071671", "l": "regulation of smooth muscle cell chemotaxis", "d": ["Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006723", "l": "cuticle hydrocarbon biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051954", "l": "positive regulation of amine transport", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061942", "l": "negative regulation of c-di-GMP signaling", "d": ["Any process that decreases the rate, frequency or extent of c-di-GMP signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006891", "l": "intra-Golgi vesicle-mediated transport", "d": ["The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097300", "l": "programmed necrotic cell death", "d": ["A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0001649", "l": "osteoblast differentiation", "d": ["The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003122", "l": "norepinephrine-mediated vasodilation", "d": ["A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042989", "l": "sequestering of actin monomers", "d": ["The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075254", "l": "negative regulation of uredospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002592", "l": "regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045902", "l": "negative regulation of translational fidelity", "d": ["Any process that decreases the ability of the translational apparatus to interpret the genetic code."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.632870622771613", "identifiers": [{"i": "GO:0051938", "l": "L-glutamate import", "d": ["The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032761", "l": "positive regulation of lymphotoxin A production", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002899", "l": "negative regulation of central B cell deletion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060970", "l": "embryonic heart tube dorsal/ventral pattern formation", "d": ["The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021573", "l": "rhombomere 7 development", "d": ["The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000487", "l": "maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019377", "l": "glycolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035221", "l": "genital disc pattern formation", "d": ["The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904330", "l": "positive regulation of myofibroblast contraction", "d": ["Any process that activates or increases the frequency, rate or extent of myofibroblast contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003064", "l": "regulation of heart rate by hormone", "d": ["The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902097", "l": "positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061263", "l": "mesonephric glomerular mesangial cell development", "d": ["The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048851", "l": "hypophysis formation", "d": ["The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006002", "l": "fructose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039593", "l": "peturbation by virus of host exit from mitosis", "d": ["A process in which a virus interferes with the host cell completing the M phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006627", "l": "protein processing involved in protein targeting to mitochondrion", "d": ["The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060734", "l": "regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055111", "l": "ingression involved in gastrulation with mouth forming second", "d": ["The migration of individual cells into the embryo involved in deuterostomic gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071384", "l": "cellular response to corticosteroid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905143", "l": "eukaryotic translation initiation factor 2 complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060605", "l": "tube lumen cavitation", "d": ["The formation of a lumen by hollowing out a solid rod or cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0001547", "l": "antral ovarian follicle growth", "d": ["Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.245311748130447", "identifiers": [{"i": "GO:0061647", "l": "histone H3-K9 modification", "d": ["The modification of histone H3 at a lysine in position 9 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021518", "l": "spinal cord commissural neuron specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901897", "l": "regulation of relaxation of cardiac muscle", "d": ["Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055045", "l": "antipodal cell degeneration", "d": ["The process in which the antipodal cells undergo programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901578", "l": "negative regulation of alkane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072325", "l": "vulval cell fate commitment", "d": ["The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903562", "l": "microtubule bundle formation involved in mitotic spindle midzone assembly", "d": ["Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002297", "l": "T-helper 2 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000085", "l": "negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140928", "l": "inhibition of non-skeletal tissue mineralization", "d": ["A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900846", "l": "regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021741", "l": "spinal trigeminal nucleus development", "d": ["The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010714", "l": "positive regulation of collagen metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "40.973077713173531", "identifiers": [{"i": "GO:0051716", "l": "cellular response to stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033274", "l": "response to vitamin B2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902959", "l": "regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021557", "l": "oculomotor nerve development", "d": ["The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904851", "l": "positive regulation of establishment of protein localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901086", "l": "benzylpenicillin metabolic process", "d": ["The chemical reactions and pathways involving benzylpenicillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900306", "l": "regulation of maltoheptaose transport", "d": ["Any process that modulates the frequency, rate or extent of maltoheptaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042186", "l": "o-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018249", "l": "protein dehydration", "d": ["The removal of a water group from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045760", "l": "positive regulation of action potential", "d": ["Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099628", "l": "neurotransmitter receptor diffusion trapping", "d": ["The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0002181", "l": "cytoplasmic translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099180", "l": "zinc ion import into synaptic vesicle", "d": ["The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002420", "l": "natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903277", "l": "negative regulation of sodium ion export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002860", "l": "positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120122", "l": "prolactin metabolic process", "d": ["The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051582", "l": "positive regulation of neurotransmitter uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061807", "l": "positive regulation of DNA recombination at centromere", "d": ["Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048926", "l": "electrosensory lateral line system development", "d": ["The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002530", "l": "regulation of systemic arterial blood pressure involved in acute-phase response", "d": ["Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901775", "l": "mitomycin C metabolic process", "d": ["The chemical reactions and pathways involving mitomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071360", "l": "cellular response to exogenous dsRNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002627", "l": "positive regulation of T cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900700", "l": "positive regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0071616", "l": "acyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901552", "l": "positive regulation of endothelial cell development", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0021594", "l": "rhombomere formation", "d": ["The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903404", "l": "positive regulation of renal phosphate excretion", "d": ["Any process that activates or increases the frequency, rate or extent of renal phosphate excretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006154", "l": "adenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019554", "l": "glutamate catabolic process to oxaloacetate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031642", "l": "negative regulation of myelination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072122", "l": "extraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090234", "l": "regulation of kinetochore assembly", "d": ["Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000267", "l": "negative regulation of blood coagulation, intrinsic pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002034", "l": "maintenance of blood vessel diameter homeostasis by renin-angiotensin", "d": ["The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001272", "l": "positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001297", "l": "N(omega)-methyl-L-arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035386", "l": "regulation of Roundabout 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[{"i": "GO:0007044", "l": "cell-substrate junction assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042549", "l": "photosystem II stabilization", "d": ["The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903323", "l": "regulation of snoRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of snoRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001953", "l": "negative regulation of cell-matrix adhesion", "d": ["Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902232", "l": "regulation of positive thymic T cell selection", "d": ["Any process that modulates the frequency, rate or extent of positive thymic T cell selection."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031460", "l": "glycine betaine transport", "d": ["The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:1905818", "l": "regulation of chromosome separation", "d": ["Any process that modulates the frequency, rate or extent of chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903943", "l": "regulation of hepatocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035944", "l": "perforin production", "d": ["The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106058", "l": "positive regulation of calcineurin-mediated signaling", "d": ["Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015913", "l": "short-chain fatty acid transmembrane transport", "d": ["The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046595", "l": "establishment of pole plasm mRNA localization", "d": ["Any process that results in the directed movement of mRNA to the oocyte pole plasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901337", "l": "thioester transport", "d": ["The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071934", "l": "thiamine transmembrane transport", "d": ["The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045347", "l": "negative regulation of MHC class II biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031991", "l": "regulation of actomyosin contractile ring contraction", "d": ["Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1904745", "l": "Atg1/ULK1 kinase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002881", "l": "negative regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070934", "l": "CRD-mediated mRNA stabilization", "d": ["An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0075261", "l": "positive regulation of spore-bearing organ development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990379", "l": "lipid transport across blood-brain barrier", "d": ["The directed movement of lipid molecules passing through the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140632", "l": "canonical inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061073", "l": "ciliary body morphogenesis", "d": ["The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072096", "l": "negative regulation of branch elongation involved in ureteric bud branching", "d": ["Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048486", "l": "parasympathetic nervous system development", "d": ["The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0035179", "l": "larval turning behavior", "d": ["Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015746", "l": "citrate transport", "d": ["The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061280", "l": "epithelial cell migration involved in mesonephric proximal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060518", "l": "cell migration involved in prostatic bud elongation", "d": ["The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900119", "l": "positive regulation of execution phase of apoptosis", "d": ["Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008103", "l": "oocyte microtubule cytoskeleton polarization", "d": ["Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905860", "l": "positive regulation of heparan sulfate proteoglycan binding", "d": ["Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.306098259633643", "identifiers": [{"i": "GO:1901657", "l": "glycosyl compound metabolic process", "d": ["The chemical reactions and pathways involving glycosyl compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902957", "l": "negative regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071514", "l": "genomic imprinting", "d": ["The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903002", "l": "positive regulation of lipid transport across blood-brain barrier", "d": ["Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070723", "l": "response to cholesterol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001120", "l": "methanofuran biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a methanofuran."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000339", "l": "negative regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1902145", "l": "regulation of response to cell cycle checkpoint signaling", "d": ["Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0086004", "l": "regulation of cardiac muscle cell contraction", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048537", "l": "mucosa-associated lymphoid tissue development", "d": ["The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904665", "l": "positive regulation of N-terminal peptidyl-methionine acetylation", "d": ["Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0072087", "l": "renal vesicle development", "d": ["The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905483", "l": "regulation of motor neuron migration", "d": ["Any process that modulates the frequency, rate or extent of motor neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0019405", "l": "alditol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070468", "l": "dentin extracellular matrix secretion", "d": ["The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001403", "l": "invasive growth in response to glucose limitation", "d": ["A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0051446", "l": "positive regulation of meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900601", "l": "endocrocin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of endocrocin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019317", "l": "fucose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0071295", "l": "cellular response to vitamin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021824", "l": "cerebral cortex tangential migration using cell-axon interactions", "d": ["The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050669", "l": "negative regulation of homocysteine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006746", "l": "FADH2 metabolic process", "d": ["The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021680", "l": "cerebellar Purkinje cell layer development", "d": ["The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904414", "l": "positive regulation of cardiac ventricle development", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac ventricle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900798", "l": "cordyol C catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cordyol C."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0001736", "l": "establishment of planar polarity", "d": ["Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021704", "l": "locus ceruleus morphogenesis", "d": ["The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060161", "l": "positive regulation of dopamine receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071422", "l": "succinate transmembrane transport", "d": ["The process in which succinate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071646", "l": "regulation of macrophage inflammatory protein-1 gamma production", "d": ["Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043536", "l": "positive regulation of blood vessel endothelial cell migration", "d": ["Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062191", "l": "galactoxylomannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903682", "l": "negative regulation of epithelial cell-cell adhesion involved in epithelium migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901856", "l": "negative regulation of cellular respiration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.47237971304007", "identifiers": [{"i": "GO:0048232", "l": "male gamete generation", "d": ["Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034132", "l": "negative regulation of toll-like receptor 1 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0043244", "l": "regulation of protein-containing complex disassembly", "d": ["Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031452", "l": "negative regulation of heterochromatin formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905592", "l": "negative regulation of optical nerve axon regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001117", "l": "tetrahydromethanopterin metabolic process", "d": ["The chemical reactions and pathways involving a tetrahydromethanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021839", "l": "interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex", "d": ["The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031113", "l": "regulation of microtubule polymerization", "d": ["Any process that modulates the frequency, rate or extent of microtubule polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000102", "l": "negative regulation of mammary stem cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902082", "l": "positive regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060038", "l": "cardiac muscle cell proliferation", "d": ["The expansion of a cardiac muscle cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043965", "l": "symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction", "d": ["A process in which a virus interferes with, inhibits or disrupts an adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904821", "l": "chloroplast disassembly", "d": ["The disaggregation of a chloroplast into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009695", "l": "jasmonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000762", "l": "pheromone-induced unidirectional conjugation", "d": ["Unidirectional transfer of genetic information triggered by to a pheromone signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051545", "l": "negative regulation of elastin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034761", "l": "positive regulation of iron ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000872", "l": "positive regulation of progesterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of progesterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035365", "l": "regulation of thymine transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0051054", "l": "positive regulation of DNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990858", "l": "cellular response to lectin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006015", "l": "5-phosphoribose 1-diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0050796", "l": "regulation of insulin secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904520", "l": "regulation of myofibroblast cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021950", "l": "chemorepulsion involved in precerebellar neuron migration", "d": ["The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060037", "l": "pharyngeal system development", "d": ["The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990505", "l": "mitotic DNA replication maintenance of fidelity", "d": ["Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.507900205332078", "identifiers": [{"i": "GO:0051235", "l": "maintenance of location", "d": ["Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000641", "l": "regulation of early endosome to late endosome transport", "d": ["Any process that modulates the frequency, rate or extent of early endosome to late endosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.391713369466018", "identifiers": [{"i": "GO:0071214", "l": "cellular response to abiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000479", "l": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046694", "l": "sperm incapacitation", "d": ["The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070625", "l": "zymogen granule exocytosis", "d": ["The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0160075", "l": "non-canonical inflammasome complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a non-canonical inflammasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015015", "l": "heparan sulfate proteoglycan biosynthetic process, enzymatic modification", "d": ["The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018888", "l": "3-chloroacrylic acid metabolic process", "d": ["The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061719", "l": "glucose catabolic process to pyruvate utilizing ADP", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900037", "l": "regulation of cellular response to hypoxia", "d": ["Any process that modulates the frequency, rate or extent of cellular response to hypoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0033240", "l": "positive regulation of amine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031138", "l": "negative regulation of conjugation with cellular fusion", "d": ["Any process that decreases the rate or frequency of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003172", "l": "sinoatrial valve development", "d": ["The progression of the sinoatrial valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0106011", "l": "regulation of protein localization to medial cortex", "d": ["Any process that regulates the localization of a protein to the medial cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039540", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072183", "l": "negative regulation of nephron tubule epithelial cell differentiation", "d": ["Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0016482", "l": "cytosolic transport", "d": ["The directed movement of substances or organelles within the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006681", "l": "galactosylceramide metabolic process", "d": ["The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0032945", "l": "negative regulation of mononuclear cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042338", "l": "cuticle development involved in collagen and cuticulin-based cuticle molting cycle", "d": ["Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900687", "l": "negative regulation of gerfelin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905724", "l": "positive regulation of trypanothione biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905408", "l": "negative regulation of creatine transmembrane transporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045429", "l": "positive regulation of nitric oxide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904052", "l": "negative regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001828", "l": "inner cell mass cellular morphogenesis", "d": ["The morphogenesis of cells in the inner cell mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000234", "l": "positive regulation of rRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of rRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019382", "l": "carbon tetrachloride catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0016197", "l": "endosomal transport", "d": ["The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002484", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904858", "l": "negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043315", "l": "positive regulation of neutrophil degranulation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0002579", "l": "positive regulation of antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150090", "l": "multiple spine synapse organization, single dendrite", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036343", "l": "psychomotor behavior", "d": ["The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901271", "l": "lipooligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipooligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0006505", "l": "GPI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043282", "l": "pharyngeal muscle development", "d": ["The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904913", "l": "regulation of establishment of protein-containing complex localization to telomere", "d": ["Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051898", "l": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046076", "l": "dTTP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019286", "l": "glycine betaine biosynthetic process from glycine", "d": ["The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150044", "l": "regulation of postsynaptic dense core vesicle exocytosis", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0043954", "l": "cellular component maintenance", "d": ["The organization process that preserves a cellular component in a stable functional or structural state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019265", "l": "glycine biosynthetic process, by transamination of glyoxylate", "d": ["The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902298", "l": "cell cycle DNA replication maintenance of fidelity", "d": ["Any maintenance of fidelity that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140217", "l": "positive regulation of D-aspartate import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000256", "l": "allantoin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0033338", "l": "medial fin development", "d": ["The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036272", "l": "response to gemcitabine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010213", "l": "non-photoreactive DNA repair", "d": ["A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990672", "l": "medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006527", "l": "arginine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070133", "l": "negative regulation of mitochondrial translational initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018976", "l": "1,2,3-tribromopropane metabolic process", "d": ["The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015880", "l": "coenzyme A transport", "d": ["The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010158", "l": "abaxial cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901910", "l": "adenosine 5'-(hexahydrogen pentaphosphate) metabolic process", "d": ["The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046433", "l": "2-aminoethylphosphonate metabolic process", "d": ["The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072235", "l": "metanephric distal tubule development", "d": ["The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045737", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CDK activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002342", "l": "central B cell deletion", "d": ["The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0022012", "l": "subpallium cell proliferation in forebrain", "d": ["The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905695", "l": "positive regulation of phosphatidic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003281", "l": "ventricular septum development", "d": ["The progression of the ventricular septum over time from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008153", "l": "para-aminobenzoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.920847010046863", "identifiers": [{"i": "GO:0034219", "l": "carbohydrate transmembrane transport", "d": ["The process in which a carbohydrate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0007567", "l": "parturition", "d": ["The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032920", "l": "putrescine acetylation", "d": ["The modification of putrescine by addition of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.081498309310845", "identifiers": [{"i": "GO:1903131", "l": "mononuclear cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141011", "l": "siRNA-mediated retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903352", "l": "L-ornithine transmembrane transport", "d": ["The directed movement of L-ornithine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060343", "l": "trabecula formation", "d": ["The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007355", "l": "anterior region determination", "d": ["Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901787", "l": "benzoyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving benzoyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070983", "l": "dendrite guidance", "d": ["The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900967", "l": "positive regulation of methanophenazine metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045173", "l": "O-sialoglycoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072211", "l": "metanephric pyramids development", "d": ["The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032186", "l": "cellular bud neck septin ring organization", "d": ["Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902839", "l": "negative regulation of nuclear migration along microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018892", "l": "cyclohexylsulfamate metabolic process", "d": ["The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0046822", "l": "regulation of nucleocytoplasmic transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903195", "l": "regulation of L-dopa biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098715", "l": "malonic acid import across plasma membrane", "d": ["The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003339", "l": "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0001824", "l": "blastocyst development", "d": ["The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070730", "l": "cAMP transport", "d": ["The directed movement of cyclic AMP (cAMP), into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060546", "l": "negative regulation of necroptotic process", "d": ["Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903623", "l": "negative regulation of RNA polymerase III activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048280", "l": "vesicle fusion with Golgi apparatus", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070360", "l": "actin polymerization-dependent cell migration in host", "d": ["The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045498", "l": "sex comb development", "d": ["The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903913", "l": "regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000430", "l": "positive regulation of neutrophil aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006580", "l": "ethanolamine metabolic process", "d": ["The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901176", "l": "lycopene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lycopene."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015691", "l": "cadmium ion transport", "d": ["The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038015", "l": "positive regulation of insulin receptor signaling pathway by insulin receptor internalization", "d": ["Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062095", "l": "endoplasmic reticulum-peroxisome tethering", "d": ["The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097410", "l": "hippocampal interneuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0120054", "l": "intestinal motility", "d": ["Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021787", "l": "chemorepulsion of branchiomotor neuron axon in neural tube", "d": ["The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001103", "l": "maltohexaose transport", "d": ["The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061330", "l": "Malpighian tubule stellate cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0098727", "l": "maintenance of cell number", "d": ["Any process by which the numbers of cells of a particular type or in a tissue are maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075183", "l": "infection cushion formation", "d": ["The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0051048", "l": "negative regulation of secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048057", "l": "R3/R4 development", "d": ["The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0001933", "l": "negative regulation of protein phosphorylation", "d": ["Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0051445", "l": "regulation of meiotic cell cycle", "d": ["Any process that modulates the rate or extent of progression through the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000051", "l": "negative regulation of non-canonical Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900182", "l": "positive regulation of protein localization to nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061986", "l": "negative regulation of transcription by glucose", "d": ["Any process involving glucose that decreases the frequency, rate or extent or transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0034204", "l": "lipid translocation", "d": ["The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003397", "l": "neuron migration involved in amphid sensory organ dendrite retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019505", "l": "resorcinol metabolic process", "d": ["The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018936", "l": "anaerobic nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002537", "l": "nitric oxide production involved in inflammatory response", "d": ["The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001004", "l": "negative regulation of pectin catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905675", "l": "negative regulation of adaptive immune memory response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0007020", "l": "microtubule nucleation", "d": ["The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019628", "l": "urate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010701", "l": "positive regulation of norepinephrine secretion", "d": ["Any process that increases the frequency, rate or extent of the regulated release of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903724", "l": "positive regulation of centriole elongation", "d": ["Any process that activates or increases the frequency, rate or extent of centriole elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903367", "l": "positive regulation of fear response", "d": ["Any process that activates or increases the frequency, rate or extent of fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000118", "l": "regulation of sodium-dependent phosphate transport", "d": ["Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0061231", "l": "mesonephric glomerulus vasculature development", "d": ["The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051190", "l": "prosthetic group catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0070486", "l": "leukocyte aggregation", "d": ["The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036517", "l": "chemoattraction of serotonergic neuron axon", "d": ["The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0000375", "l": "RNA splicing, via transesterification reactions", "d": ["Splicing of RNA via a series of two transesterification reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902215", "l": "negative regulation of interleukin-4-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0071774", "l": "response to fibroblast growth factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904142", "l": "negative regulation of carotenoid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000901", "l": "cyclodextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cyclodextrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0035108", "l": "limb morphogenesis", "d": ["The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140146", "l": "calcium ion import into vacuole", "d": ["The directed movement of calcium cations into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007035", "l": "vacuolar acidification", "d": ["Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905110", "l": "negative regulation of pulmonary blood vessel remodeling", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905914", "l": "positive regulation of calcium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0055057", "l": "neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002607", "l": "regulation of myeloid dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071896", "l": "protein localization to adherens junction", "d": ["Any process in which a protein is transported to, and/or maintained at the adherens junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140028", "l": "pore formation during contractile vacuole discharge", "d": ["The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090008", "l": "hypoblast development", "d": ["The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044555", "l": "negative regulation of heart rate in another organism", "d": ["Any process that stops, prevents or reduces the frequency of heart contraction of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990052", "l": "ER to chloroplast lipid transport", "d": ["The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045175", "l": "basal protein localization", "d": ["Any process in which a protein is transported to, or maintained in, basal regions of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900216", "l": "positive regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090495", "l": "low-density lipoprotein particle disassembly", "d": ["The disaggregation of a low-density lipoprotein particle into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072050", "l": "S-shaped body morphogenesis", "d": ["The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097206", "l": "nephrocyte filtration", "d": ["The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019465", "l": "aspartate transamidation", "d": ["The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0046755", "l": "viral budding", "d": ["A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901725", "l": "regulation of histone deacetylase activity", "d": ["Any process that modulates the frequency, rate or extent of histone deacetylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003382", "l": "epithelial cell morphogenesis", "d": ["The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045684", "l": "positive regulation of epidermis development", "d": ["Any process that activates or increases the frequency, rate or extent of epidermis development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061116", "l": "ductus venosus closure", "d": ["The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060598", "l": "dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis", "d": ["The process in which the terminal end of a mammary duct bifurcates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016973", "l": "poly(A)+ mRNA export from nucleus", "d": ["The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000519", "l": "positive regulation of T-helper 1 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002781", "l": "antifungal peptide production", "d": ["The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061340", "l": "establishment or maintenance of monopolar cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019643", "l": "reductive tricarboxylic acid cycle", "d": ["A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000954", "l": "methionine catabolic process to 3-methylthiopropanoate", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904240", "l": "negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046056", "l": "dADP metabolic process", "d": ["The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072300", "l": "positive regulation of metanephric glomerulus development", "d": ["Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032057", "l": "negative regulation of translational initiation in response to stress", "d": ["Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097049", "l": "motor neuron apoptotic process", "d": ["Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000940", "l": "negative regulation of plant-type cell wall cellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0006482", "l": "protein demethylation", "d": ["The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901274", "l": "2-dehydro-3-deoxy-D-gluconic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046373", "l": "L-arabinose metabolic process", "d": ["The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033258", "l": "plastid DNA metabolic process", "d": ["The chemical reactions and pathways involving plastid DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030889", "l": "negative regulation of B cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902856", "l": "negative regulation of non-motile cilium assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031949", "l": "regulation of glucocorticoid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0086017", "l": "Purkinje myocyte action potential", "d": ["An action potential that occurs in a Purkinje myocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099610", "l": "action potential initiation", "d": ["The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060813", "l": "anterior mRNA localization involved in anterior/posterior axis specification", "d": ["Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061944", "l": "negative regulation of protein K48-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903547", "l": "regulation of growth hormone activity", "d": ["Any process that modulates the frequency, rate or extent of growth hormone activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018247", "l": "protein-phosphoribosyl dephospho-coenzyme A linkage", "d": ["The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072269", "l": "metanephric long descending thin limb development", "d": ["The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0008593", "l": "regulation of Notch signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the Notch signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042857", "l": "chrysobactin metabolic process", "d": ["The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060019", "l": "radial glial cell differentiation", "d": ["The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001825", "l": "blastocyst formation", "d": ["The initial formation of a blastocyst from a solid ball of cells known as a morula."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.421868923100455", "identifiers": [{"i": "GO:0002790", "l": "peptide secretion", "d": ["The controlled release of a peptide from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900824", "l": "positive regulation of ergot alkaloid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032826", "l": "regulation of natural killer cell differentiation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051396", "l": "positive regulation of nerve growth factor receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045856", "l": "positive regulation of pole plasm oskar mRNA localization", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000983", "l": "regulation of ATP citrate synthase activity", "d": ["Any process that modulates the frequency, rate or extent of ATP citrate synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039003", "l": "pronephric field specification", "d": ["The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010846", "l": "activation of reciprocal meiotic recombination", "d": ["Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120066", "l": "pyloric canal smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019122", "l": "peptidyl-D-alanine racemization", "d": ["The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000198", "l": "negative regulation of ribonucleoprotein complex localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032601", "l": "connective tissue growth factor production", "d": ["The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0042048", "l": "olfactory behavior", "d": ["The behavior of an organism in response to an odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006700", "l": "C21-steroid hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905654", "l": "regulation of artery smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of artery smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031129", "l": "inductive cell-cell signaling", "d": ["Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010640", "l": "regulation of platelet-derived growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071366", "l": "cellular response to indolebutyric acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048760", "l": "plant parenchymal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045642", "l": "positive regulation of basophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of basophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061688", "l": "glycolytic process via Entner-Doudoroff Pathway", "d": ["A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0048241", "l": "epinephrine transport", "d": ["The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140460", "l": "response to Gram-negative bacterium", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120068", "l": "regulation of stomach fundus smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901491", "l": "negative regulation of lymphangiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036295", "l": "cellular response to increased oxygen levels", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000235", "l": "regulation of tRNA processing", "d": ["Any process that modulates the frequency, rate or extent of tRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160049", "l": "negative regulation of cGAS/STING signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000282", "l": "regulation of cellular amino acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032000", "l": "positive regulation of fatty acid beta-oxidation", "d": ["Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045719", "l": "negative regulation of glycogen biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0008614", "l": "pyridoxine metabolic process", "d": ["The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036493", "l": "positive regulation of translation in response to endoplasmic reticulum stress", "d": ["Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106395", "l": "positive regulation of palmitic acid catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of a palmitic acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.174459315679599", "identifiers": [{"i": "GO:0018193", "l": "peptidyl-amino acid modification", "d": ["The alteration of an amino acid residue in a peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021948", "l": "inward migration of deep nuclear neurons", "d": ["The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0009855", "l": "determination of bilateral symmetry", "d": ["The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075043", "l": "melanization of appressorium wall", "d": ["The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010760", "l": "negative regulation of macrophage chemotaxis", "d": ["Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072195", "l": "kidney smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903420", "l": "protein localization to endoplasmic reticulum tubular network", "d": ["A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900004", "l": "negative regulation of serine-type endopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006863", "l": "purine nucleobase transport", "d": ["The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905187", "l": "negative regulation of metaphase/anaphase transition of meiosis I", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0044837", "l": "actomyosin contractile ring organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010968", "l": "regulation of microtubule nucleation", "d": ["Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902473", "l": "regulation of protein localization to synapse", "d": ["Any process that modulates the frequency, rate or extent of protein localization to synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032327", "l": "W-molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010874", "l": "regulation of cholesterol efflux", "d": ["Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034127", "l": "regulation of MyD88-independent toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.761895506129477", "identifiers": [{"i": "GO:0044403", "l": "biological process involved in symbiotic interaction", "d": ["A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0033013", "l": "tetrapyrrole metabolic process", "d": ["The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035766", "l": "cell chemotaxis to fibroblast growth factor", "d": ["The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010058", "l": "regulation of atrichoblast fate specification", "d": ["Any process that modulates atrichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002425", "l": "tolerance induction in urogenital tract", "d": ["Tolerance induction taking place in the urogenital tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0046271", "l": "phenylpropanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030651", "l": "peptide antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904944", "l": "positive regulation of cardiac ventricle formation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903861", "l": "positive regulation of dendrite extension", "d": ["Any process that activates or increases the frequency, rate or extent of dendrite extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0001755", "l": "neural crest cell migration", "d": ["The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006892", "l": "post-Golgi vesicle-mediated transport", "d": ["The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002307", "l": "CD8-positive, alpha-beta regulatory T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048047", "l": "mating behavior, sex discrimination", "d": ["The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0110009", "l": "formin-nucleated actin cable organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003285", "l": "septum secundum development", "d": ["The progression of the septum secundum over time, from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016540", "l": "protein autoprocessing", "d": ["Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035531", "l": "regulation of chemokine (C-C motif) ligand 6 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060692", "l": "mesenchymal cell differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1904746", "l": "negative regulation of apoptotic process involved in development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006930", "l": "substrate-dependent cell migration, cell extension", "d": ["The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002496", "l": "proteolysis associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903995", "l": "regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072672", "l": "neutrophil extravasation", "d": ["The migration of a neutrophil from the blood vessels into the surrounding tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070668", "l": "positive regulation of mast cell proliferation", "d": ["Any process that activates or increases the rate or extent of mast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905943", "l": "negative regulation of formation of growth cone in injured axon", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035570", "l": "N-terminal peptidyl-serine methylation", "d": ["The methylation of the N-terminal serine of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000886", "l": "glucuronoxylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902599", "l": "sulfathiazole transmembrane transport", "d": ["The directed movement of sulfathiazole across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070807", "l": "positive regulation of phialide development", "d": ["Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0018965", "l": "s-triazine compound metabolic process", "d": ["The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0018107", "l": "peptidyl-threonine phosphorylation", "d": ["The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070629", "l": "(1->4)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903393", "l": "positive regulation of adherens junction organization", "d": ["Any process that activates or increases the frequency, rate or extent of adherens junction organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001880", "l": "Mullerian duct regression", "d": ["The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021845", "l": "neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration", "d": ["The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034971", "l": "histone H3-R17 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002723", "l": "positive regulation of B cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106393", "l": "regulation of palmitic acid catabolic process", "d": ["Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0006312", "l": "mitotic recombination", "d": ["The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034194", "l": "D-galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002072", "l": "optic cup morphogenesis involved in camera-type eye development", "d": ["The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016036", "l": "cellular response to phosphate starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000971", "l": "tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060459", "l": "left lung development", "d": ["The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080173", "l": "male-female gamete recognition during double fertilization forming a zygote and endosperm", "d": ["The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003248", "l": "heart capillary growth", "d": ["The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0007598", "l": "blood coagulation, extrinsic pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902033", "l": "regulation of hematopoietic stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080020", "l": "regulation of coenzyme A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045894", "l": "negative regulation of mating-type specific transcription, DNA-templated", "d": ["Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140048", "l": "manganese ion export across plasma membrane", "d": ["The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009240", "l": "isopentenyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061336", "l": "cell morphogenesis involved in Malpighian tubule morphogenesis", "d": ["The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001200", "l": "positive regulation of dendritic cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045796", "l": "negative regulation of intestinal cholesterol absorption", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032322", "l": "ubiquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072731", "l": "cellular response to papulacandin B", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007359", "l": "posterior abdomen determination", "d": ["The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048917", "l": "posterior lateral line ganglion development", "d": ["The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060731", "l": "positive regulation of intestinal epithelial structure maintenance", "d": ["Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0010393", "l": "galacturonan metabolic process", "d": ["The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.693743768401106", "identifiers": [{"i": "GO:0042246", "l": "tissue regeneration", "d": ["The regrowth of lost or destroyed tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044349", "l": "DNA excision", "d": ["The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0034407", "l": "cell wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0034331", "l": "cell junction maintenance", "d": ["The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048361", "l": "root epithelial mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904479", "l": "negative regulation of intestinal absorption", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900670", "l": "regulation of F-9775A biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0018970", "l": "toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043310", "l": "negative regulation of eosinophil degranulation", "d": ["Any process that stops, prevents, or reduces the rate of eosinophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902664", "l": "positive regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0062163", "l": "pseudohyphal septin ring assembly", "d": ["The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006435", "l": "threonyl-tRNA aminoacylation", "d": ["The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0019954", "l": "asexual reproduction", "d": ["A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033572", "l": "transferrin transport", "d": ["The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061230", "l": "mesonephric juxtaglomerulus cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042481", "l": "regulation of odontogenesis", "d": ["Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070880", "l": "fungal-type cell wall beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044529", "l": "regulation of mitochondrial rRNA stability", "d": ["Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006230", "l": "TMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045655", "l": "regulation of monocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of monocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032061", "l": "negative regulation of translation in response to osmotic stress", "d": ["Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045644", "l": "negative regulation of eosinophil differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "47.55960263780473", "identifiers": [{"i": "GO:0006996", "l": "organelle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0098534", "l": "centriole assembly", "d": ["A cellular process that results in the assembly of one or more centrioles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900187", "l": "regulation of cell adhesion involved in single-species biofilm formation", "d": ["Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001717", "l": "conversion of seryl-tRNAsec to selenocys-tRNAsec", "d": ["The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903389", "l": "negative regulation of synaptic vesicle uncoating", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140990", "l": "primary piRNA processing", "d": ["The process involved in converting precursor piRNAs into non-overlapping, contiguous primary piRNAs (approximately 24-30-nt piRNAs with a preference for a 5' uridine (U) via the endonucleolytic activity of cytosolic PIWI. This may include pre-piRNA maturation of 3' ends by trimming and 2'-O-methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071925", "l": "thymic stromal lymphopoietin production", "d": ["The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090212", "l": "negative regulation of establishment of blood-brain barrier", "d": ["Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051695", "l": "actin filament uncapping", "d": ["The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071287", "l": "cellular response to manganese ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033979", "l": "box H/ACA RNA metabolic process", "d": ["The chemical reactions and pathways involving box H/ACA type small nucleolar RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014842", "l": "regulation of skeletal muscle satellite cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036280", "l": "cellular response to L-canavanine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021745", "l": "nucleus ambiguus development", "d": ["The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099176", "l": "regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090323", "l": "prostaglandin secretion involved in immune response", "d": ["The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002666", "l": "positive regulation of T cell tolerance induction", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070365", "l": "hepatocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043971", "l": "histone H3-K18 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0070948", "l": "regulation of neutrophil mediated cytotoxicity", "d": ["Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0003307", "l": "regulation of Wnt signaling pathway involved in heart development", "d": ["Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009604", "l": "detection of symbiotic bacterium", "d": ["The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141082", "l": "symbiont-mediated detoxification of host-generated reactive oxygen species", "d": ["A process in which a symbiont interferes with, inhibits or disrupts the host reactive oxygen species (ROS)-mediated innate immune response by directly degrading host ROS. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099553", "l": "trans-synaptic signaling by endocannabinoid, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046931", "l": "pore complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1901419", "l": "regulation of response to alcohol", "d": ["Any process that modulates the frequency, rate or extent of response to alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0018211", "l": "peptidyl-tryptophan modification", "d": ["The chemical alteration of a tryptophan residue in a peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.381710255175513", "identifiers": [{"i": "GO:0044092", "l": "negative regulation of molecular function", "d": ["Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033378", "l": "establishment of protease localization to T cell secretory granule", "d": ["The directed movement of a protease to a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016555", "l": "uridine to cytidine editing", "d": ["The conversion of a uridine residue to cytosine in an RNA molecule by amination."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905395", "l": "response to flavonoid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0033152", "l": "immunoglobulin V(D)J recombination", "d": ["The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904590", "l": "negative regulation of protein import", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein import."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032006", "l": "regulation of TOR signaling", "d": ["Any process that modulates the frequency, rate or extent of TOR signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042538", "l": "hyperosmotic salinity response", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905778", "l": "negative regulation of exonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120061", "l": "negative regulation of gastric emptying", "d": ["Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050901", "l": "leukocyte tethering or rolling", "d": ["Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1903791", "l": "uracil transmembrane transport", "d": ["The process in which uracil is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044655", "l": "phagosome reneutralization", "d": ["Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0009880", "l": "embryonic pattern specification", "d": ["The process that results in the patterns of cell differentiation that will arise in an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003058", "l": "hormonal regulation of the force of heart contraction", "d": ["The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010378", "l": "temperature compensation of the circadian clock", "d": ["The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0030071", "l": "regulation of mitotic metaphase/anaphase transition", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060488", "l": "orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates perpendicular to the plane of the previous bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030575", "l": "nuclear body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010988", "l": "regulation of low-density lipoprotein particle clearance", "d": ["Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033491", "l": "coniferin metabolic process", "d": ["The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0042417", "l": "dopamine metabolic process", "d": ["The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0085029", "l": "extracellular matrix assembly", "d": ["The aggregation, arrangement and bonding together of the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0141008", "l": "retrotransposon silencing by mRNA destabilization", "d": ["A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070790", "l": "phialide development", "d": ["The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905277", "l": "negative regulation of epithelial tube formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051520", "l": "termination of bipolar cell growth", "d": ["Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061141", "l": "lung ciliated cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903771", "l": "positive regulation of beta-galactosidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006957", "l": "complement activation, alternative pathway", "d": ["Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010215", "l": "cellulose microfibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042441", "l": "eye pigment metabolic process", "d": ["The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110003", "l": "regulation of tRNA C5-cytosine methylation", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000905", "l": "negative regulation of starch metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900127", "l": "positive regulation of hyaluronan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000594", "l": "positive regulation of metanephric DCT cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120268", "l": "paraflagellar rod assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900440", "l": "regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048504", "l": "regulation of timing of animal organ formation", "d": ["Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:1901342", "l": "regulation of vasculature development", "d": ["Any process that modulates the frequency, rate or extent of vasculature development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002302", "l": "CD8-positive, alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019327", "l": "lead sulfide oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905282", "l": "regulation of epidermal growth factor receptor signaling pathway involved in heart process", "d": ["Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060298", "l": "positive regulation of sarcomere organization", "d": ["Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009559", "l": "embryo sac central cell differentiation", "d": ["The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030838", "l": "positive regulation of actin filament polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of actin polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0002445", "l": "type II hypersensitivity", "d": ["An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035041", "l": "sperm DNA decondensation", "d": ["Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "38.162955126451941", "identifiers": [{"i": "GO:0035209", "l": "pupal development", "d": ["The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009720", "l": "detection of hormone stimulus", "d": ["The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904613", "l": "cellular response to 2,3,7,8-tetrachlorodibenzodioxine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021632", "l": "optic nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904117", "l": "cellular response to vasopressin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009717", "l": "isoflavonoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0019577", "l": "aldaric acid metabolic process", "d": ["The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032803", "l": "regulation of low-density lipoprotein particle receptor catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035456", "l": "response to interferon-beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048929", "l": "efferent axon development in posterior lateral line nerve", "d": ["The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021574", "l": "rhombomere 8 development", "d": ["The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0072599", "l": "establishment of protein localization to endoplasmic reticulum", "d": ["The directed movement of a protein to a specific location in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902610", "l": "response to N-phenylthiourea", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010089", "l": "xylem development", "d": ["The formation of the principal water-conducting tissue of a vascular plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0002536", "l": "respiratory burst involved in inflammatory response", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001230", "l": "positive regulation of response to gamma radiation", "d": ["Any process that activates or increases the frequency, rate or extent of response to gamma radiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035812", "l": "renal sodium excretion", "d": ["The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900020", "l": "positive regulation of protein kinase C activity", "d": ["Any process that activates or increases the frequency, rate or extent of protein kinase C activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905491", "l": "positive regulation of sensory neuron axon guidance", "d": ["Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045299", "l": "otolith mineralization", "d": ["The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000468", "l": "regulation of peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904277", "l": "negative regulation of wax biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0017000", "l": "antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900032", "l": "regulation of trichome patterning", "d": ["Any process that modulates the frequency, rate or extent of trichome patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900664", "l": "regulation of emodin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of emodin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046712", "l": "GDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904617", "l": "negative regulation of actin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of actin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021805", "l": "cell movement involved in somal translocation", "d": ["The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051600", "l": "regulation of endocytosis by exocyst localization", "d": ["Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097717", "l": "copper ion transport across blood-cerebrospinal fluid barrier", "d": ["The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900084", "l": "regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1904478", "l": "regulation of intestinal absorption", "d": ["Any process that modulates the frequency, rate or extent of intestinal absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0034398", "l": "telomere tethering at nuclear periphery", "d": ["The process in which a telomere is maintained in a specific location at the nuclear periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0050916", "l": "sensory perception of sweet taste", "d": ["The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015792", "l": "arabinitol transmembrane transport", "d": ["The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900134", "l": "negative regulation of renin secretion into blood stream", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061074", "l": "regulation of neural retina development", "d": ["Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090222", "l": "centrosome-templated microtubule nucleation", "d": ["The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030210", "l": "heparin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051620", "l": "norepinephrine uptake", "d": ["The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061678", "l": "Entner-Doudoroff pathway", "d": ["A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0035987", "l": "endodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0090626", "l": "plant epidermis morphogenesis", "d": ["The process in which the anatomical structures of the plant epidermis are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009294", "l": "DNA-mediated transformation", "d": ["The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901106", "l": "tetracenomycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracenomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070425", "l": "negative regulation of nucleotide-binding oligomerization domain containing signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0048334", "l": "regulation of mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060894", "l": "limb spinous cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902048", "l": "neosartoricin metabolic process", "d": ["The chemical reactions and pathways involving neosartoricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.771456014425979", "identifiers": [{"i": "GO:0043687", "l": "post-translational protein modification", "d": ["The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006207", "l": "'de novo' pyrimidine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900264", "l": "positive regulation of DNA-directed DNA polymerase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002849", "l": "regulation of peripheral T cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035946", "l": "mitochondrial mRNA surveillance", "d": ["The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060768", "l": "regulation of epithelial cell proliferation involved in prostate gland development", "d": ["Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075201", "l": "penetration hypha formation", "d": ["The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002352", "l": "B cell negative selection", "d": ["Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.115557823092956", "identifiers": [{"i": "GO:0006950", "l": "response to stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0097722", "l": "sperm motility", "d": ["Any process involved in the controlled movement of a sperm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000025", "l": "regulation of leaf formation", "d": ["Any process that modulates the frequency, rate or extent of leaf formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002807", "l": "positive regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106400", "l": "double-strand break repair via transcription-associated homologous recombination", "d": ["A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070429", "l": "negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0097711", "l": "ciliary basal body-plasma membrane docking", "d": ["The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane."]}, {"i": "REACT:R-HSA-5620912.1", "d": []}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904007", "l": "positive regulation of phospholipase D activity", "d": ["Any process that activates or increases the frequency, rate or extent of phospholipase D activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035318", "l": "imaginal disc-derived wing hair outgrowth", "d": ["Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036074", "l": "metaplastic ossification", "d": ["Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032667", "l": "regulation of interleukin-23 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-23 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010135", "l": "ureide metabolic process", "d": ["The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010353", "l": "response to trehalose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002085", "l": "inhibition of neuroepithelial cell differentiation", "d": ["Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904812", "l": "rRNA acetylation involved in maturation of SSU-rRNA", "d": ["Any rRNA acetylation that is involved in maturation of SSU-rRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052164", "l": "symbiont defense to host-produced reactive oxygen species", "d": ["A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035915", "l": "pore formation in membrane of another organism", "d": ["The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900653", "l": "negative regulation of demethylkotanin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090539", "l": "peptide pheromone export by transmembrane transport", "d": ["The directed movement of a peptide pheromone across a membrane and out of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032740", "l": "positive regulation of interleukin-17 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902764", "l": "positive regulation of embryonic skeletal joint development", "d": ["Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905608", "l": "positive regulation of presynapse assembly", "d": ["Any process that activates or increases the frequency, rate or extent of presynapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902394", "l": "positive regulation of exodeoxyribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098838", "l": "folate transmembrane transport", "d": ["The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018250", "l": "peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine", "d": ["The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900603", "l": "tensidol A metabolic process", "d": ["The chemical reactions and pathways involving tensidol A."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1900150", "l": "regulation of defense response to fungus", "d": ["Any process that modulates the frequency, rate or extent of defense response to fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900879", "l": "(Z)-nonadeca-1,14-diene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002621", "l": "positive regulation of non-professional antigen presenting cell antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075242", "l": "negative regulation of zoospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002839", "l": "positive regulation of immune response to tumor cell", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902173", "l": "negative regulation of keratinocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043688", "l": "conversion of aspartyl-tRNA to asparaginyl-tRNA", "d": ["The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900521", "l": "regulation of response to amylopectin", "d": ["Any process that modulates the frequency, rate or extent of response to amylopectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.093520287766694", "identifiers": [{"i": "GO:0045088", "l": "regulation of innate immune response", "d": ["Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043944", "l": "negative regulation of asexual sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000918", "l": "division septum site selection", "d": ["The process of marking the site where a division septum will form."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0072164", "l": "mesonephric tubule development", "d": ["The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045950", "l": "negative regulation of mitotic recombination", "d": ["Any process that inhibits or decreases the rate of DNA recombination during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0062111", "l": "zinc ion import into organelle", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905620", "l": "negative regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002555", "l": "histamine secretion by platelet", "d": ["The regulated release of histamine by a platelet or group of platelets."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071300", "l": "cellular response to retinoic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035470", "l": "positive regulation of vascular wound healing", "d": ["Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046348", "l": "amino sugar catabolic process", "d": ["The chemical 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903917", "l": "positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0100011", "l": "positive regulation of fever generation by prostaglandin secretion", "d": ["Any prostaglandin secretion process that positively_regulates fever generation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046948", "l": "hydroxylysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.290762085176738", "identifiers": [{"i": "GO:0002562", "l": "somatic diversification of immune receptors via germline recombination within a single locus", "d": ["The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009201", "l": "ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032848", "l": "negative regulation of cellular pH reduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045778", "l": "positive regulation of ossification", "d": ["Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900236", "l": "positive regulation of Kit signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Kit signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060313", "l": "negative regulation of blood vessel remodeling", "d": ["Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015704", "l": "cyanate transport", "d": ["The directed movement of cyanate, 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Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032647", "l": "regulation of interferon-alpha production", "d": ["Any process that modulates the frequency, rate, or extent of interferon-alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070244", "l": "negative regulation of thymocyte apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045746", "l": "negative regulation of Notch signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902124", "l": "(+)-pinoresinol metabolic process", "d": ["The chemical reactions and pathways involving (+)-pinoresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060666", "l": "dichotomous subdivision of terminal units involved in salivary gland branching", "d": ["The process in which a salivary epithelial cord bifurcates at its end."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032288", "l": "myelin assembly", "d": ["The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072037", "l": "mesenchymal stem cell differentiation involved in nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039505", "l": "suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II", "d": ["Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033658", "l": "disruption by symbiont of host chloroplast thylakoid", "d": ["The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080179", "l": "1-methylguanosine metabolic process", "d": ["The chemical reactions and pathways involving 1-methylguanosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.602212321893283", "identifiers": [{"i": "GO:0048585", "l": "negative regulation of response to stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043007", "l": "maintenance of rDNA", "d": ["Any process involved in sustaining the fidelity and copy number of rDNA repeats."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090201", "l": "negative regulation of release of cytochrome c from mitochondria", "d": ["Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018159", "l": "peptidyl-methionine oxidation", "d": ["The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035268", "l": "protein mannosylation", "d": ["The addition of a mannose residue to a protein acceptor molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902974", "l": "meiotic DNA replication initiation", "d": ["Any DNA replication initiation involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903968", "l": "cellular response to micafungin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015805", "l": "S-adenosyl-L-methionine transport", "d": ["The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006105", "l": "succinate metabolic process", "d": ["The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0043618", "l": "regulation of transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048542", "l": "lymph gland development", "d": ["The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019607", "l": "phenylethylamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061220", "l": "mesonephric macula densa development", "d": ["The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060263", "l": "regulation of respiratory burst", "d": ["Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015716", "l": "organic phosphonate transport", "d": ["The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001829", "l": "trophectodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033629", "l": "negative regulation of cell adhesion mediated by integrin", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905090", "l": "negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034051", "l": "negative regulation of plant-type hypersensitive response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.468128090455764", "identifiers": [{"i": "GO:0006836", "l": "neurotransmitter transport", "d": ["The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904453", "l": "positive regulation of potassium:proton exchanging ATPase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014733", "l": "regulation of skeletal muscle adaptation", "d": ["Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048830", "l": "adventitious root development", "d": ["The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044752", "l": "response to human chorionic gonadotropin", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070610", "l": "regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060834", "l": "oral/aboral axis specification", "d": ["The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042794", "l": "plastid rRNA transcription", "d": ["The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018147", "l": "molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)", "d": ["The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902631", "l": "negative regulation of membrane hyperpolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051333", "l": "meiotic nuclear membrane reassembly", "d": ["The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0031330", "l": "negative regulation of cellular catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018429", "l": "copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide", "d": ["The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035934", "l": "corticosterone secretion", "d": ["The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140654", "l": "tryprostatin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tryprostatin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900443", "l": "regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010321", "l": "regulation of vegetative phase change", "d": ["Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036451", "l": "cap mRNA methylation", "d": ["Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1902315", "l": "nuclear cell cycle DNA replication initiation", "d": ["Any DNA replication initiation that is involved in nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016345", "l": "female meiotic chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900501", "l": "negative regulation of butyryl-CoA catabolic process to butyrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:2000257", "l": "regulation of protein activation cascade", "d": ["Any process that modulates the frequency, rate or extent of protein activation cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080113", "l": "regulation of seed growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the seed of an plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000060", "l": "positive regulation of ubiquitin-dependent protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018207", "l": "peptidyl-phenylalanine modification", "d": ["The modification of peptidyl-phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0002293", "l": "alpha-beta T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140203", "l": "spermidine import across plasma membrane", "d": ["The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048744", "l": "negative regulation of skeletal muscle fiber development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003099", "l": "positive regulation of the force of heart contraction by chemical signal", "d": ["Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900320", "l": "positive regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070562", "l": "regulation of vitamin D receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051058", "l": "negative regulation of small GTPase mediated signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002867", "l": "regulation of B cell deletion", "d": ["Any process that modulates the frequency, rate, or extent of B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071491", "l": "cellular response to red light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150151", "l": "regulation of interleukin-17A production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-17A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048395", "l": "regulation of intermediate mesodermal cell fate determination", "d": ["Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001803", "l": "regulation of type III hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061472", "l": "karyomere membrane fusion", "d": ["Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990438", "l": "U6 2'-O-snRNA methylation", "d": ["The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032639", "l": "TRAIL production", "d": ["The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000605", "l": "positive regulation of secondary growth", "d": ["Any process that activates or increases the frequency, rate or extent of secondary growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901609", "l": "negative regulation of vesicle transport along microtubule", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150191", "l": "positive regulation of interleukin-32 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-32 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903703", "l": "enterocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051585", "l": "negative regulation of dopamine uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900734", "l": "positive regulation of polyketide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000491", "l": "positive regulation of hepatic stellate cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.632188235961429", "identifiers": [{"i": "GO:0043436", "l": "oxoacid metabolic process", "d": ["The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045046", "l": "protein import into peroxisome membrane", "d": ["The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000291", "l": "regulation of myoblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of myoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060483", "l": "lobar bronchus mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030719", "l": "P granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034408", "l": "ascospore wall beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905665", "l": "positive regulation of calcium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.312708028507217", "identifiers": [{"i": "GO:0048593", "l": "camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034727", "l": "piecemeal microautophagy of the nucleus", "d": ["Degradation of a cell nucleus by lysosomal microautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902270", "l": "(R)-carnitine transmembrane transport", "d": ["The process in which (R)-carnitine is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000697", "l": "negative regulation of epithelial cell differentiation involved in kidney development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006548", "l": "histidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009819", "l": "drought recovery", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021710", "l": "cerebellar stellate cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903276", "l": "regulation of sodium ion export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007529", "l": "establishment of synaptic specificity at neuromuscular junction", "d": ["The biological process in which a synapse between a motor neuron and a muscle is initially formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0000959", "l": "mitochondrial RNA metabolic process", "d": ["The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0048266", "l": "behavioral response to pain", "d": ["Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097280", "l": "histamine secretion mediated by immunoglobulin", "d": ["Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.316995470978959", "identifiers": [{"i": "GO:0015812", "l": "gamma-aminobutyric acid transport", "d": ["The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902487", "l": "protein localization to non-growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031146", "l": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.423552501508112", "identifiers": [{"i": "GO:0022409", "l": "positive regulation of cell-cell adhesion", "d": ["Any process that activates or increases the rate or extent of cell adhesion to another cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000491", "l": "small nucleolar ribonucleoprotein complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905461", "l": "positive regulation of vascular associated smooth muscle cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0120034", "l": "positive regulation of plasma membrane bounded cell projection assembly", "d": ["Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902016", "l": "poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010188", "l": "response to microbial phytotoxin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036090", "l": "cleavage furrow ingression", "d": ["Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141080", "l": "symbiont-mediated activation of host interferon signaling pathway", "d": ["A process in which a symbiont subverts an interferon-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000341", "l": "regulation of chemokine (C-X-C motif) ligand 2 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.577164708155649", "identifiers": [{"i": "GO:0006814", "l": "sodium ion transport", "d": ["The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902597", "l": "positive regulation of DNA replication origin binding", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication origin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090473", "l": "lys-arg specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007487", "l": "analia development", "d": ["The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010645", "l": "regulation of cell communication by chemical coupling", "d": ["Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014076", "l": "response to fluoxetine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070541", "l": "response to platinum ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000179", "l": "positive regulation of neural precursor cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060316", "l": "positive regulation of ryanodine-sensitive calcium-release channel activity", "d": ["Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070370", "l": "cellular heat acclimation", "d": ["Any process that increases heat tolerance of a cell in response to high temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1902657", "l": "protein localization to prospore membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a prospore membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0006487", "l": "protein N-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060347", "l": "heart trabecula formation", "d": ["The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0006570", "l": "tyrosine metabolic process", "d": ["The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0034310", "l": "primary alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900685", "l": "positive regulation of fumonisin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070586", "l": "cell-cell adhesion involved in gastrulation", "d": ["The attachment of one cell to another cell affecting gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032255", "l": "maintenance of secretory granule location", "d": ["Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060955", "l": "neural crest-derived cardiac glial cell fate commitment", "d": ["The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009447", "l": "putrescine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060543", "l": "negative regulation of strand invasion", "d": ["Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039691", "l": "double stranded viral RNA replication", "d": ["A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0045137", "l": "development of primary sexual characteristics", "d": ["The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019128", "l": "peptidyl-tryptophan racemization", "d": ["The racemization of peptidyl-tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071286", "l": "cellular response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032435", "l": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900468", "l": "regulation of phosphatidylserine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034136", "l": "negative regulation of toll-like receptor 2 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062121", "l": "linear element maturation", "d": ["The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018882", "l": "(+)-camphor metabolic process", "d": ["The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010124", "l": "phenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009146", "l": "purine nucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903651", "l": "positive regulation of cytoplasmic transport", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009444", "l": "pyruvate oxidation", "d": ["The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016261", "l": "selenocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902108", "l": "regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046219", "l": "indolalkylamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003320", "l": "heart rudiment involution", "d": ["The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0089722", "l": "phosphoenolpyruvate transmembrane transport", "d": ["The directed movement of phosphoenolpytuvate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033319", "l": "UDP-D-xylose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036299", "l": "non-recombinational interstrand cross-link repair", "d": ["Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033145", "l": "positive regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001947", "l": "heart looping", "d": ["The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060130", "l": "thyroid-stimulating hormone-secreting cell development", "d": ["The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160020", "l": "positive regulation of ferroptosis", "d": ["Any process that activates or increases the frequency, rate or extent of ferroptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052026", "l": "modulation by symbiont of host transcription", "d": ["Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036247", "l": "phytochelatin 3 import into vacuole", "d": ["The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.594648570918388", "identifiers": [{"i": "GO:1901137", "l": "carbohydrate derivative biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbohydrate derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030466", "l": "silent mating-type cassette heterochromatin formation", "d": ["Repression of transcription at silent mating-type loci by alteration of the structure of chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010845", "l": "positive regulation of reciprocal meiotic recombination", "d": ["Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048572", "l": "short-day photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051610", "l": "serotonin uptake", "d": ["The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007060", "l": "male meiosis chromosome segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045603", "l": "positive regulation of endothelial cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0072048", "l": "renal system pattern specification", "d": ["Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043953", "l": "protein transport by the Tat complex", "d": ["The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.412000789628095", "identifiers": [{"i": "GO:0045619", "l": "regulation of lymphocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904025", "l": "positive regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1903555", "l": "regulation of tumor necrosis factor superfamily cytokine production", "d": ["Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001997", "l": "positive regulation of the force of heart contraction by epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072667", "l": "maintenance of protein location in vacuole", "d": ["Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110012", "l": "protein localization to P-body", "d": ["Any process in which a protein is transported to, or maintained at, a P-body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070712", "l": "RNA cytidine-uridine insertion", "d": ["The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003052", "l": "circadian regulation of systemic arterial blood pressure", "d": ["Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090143", "l": "nucleoid organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903712", "l": "cysteine transmembrane transport", "d": ["The directed movement of cysteine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901351", "l": "regulation of phosphatidylglycerol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045018", "l": "retrograde transport, vacuole to Golgi", "d": ["The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060607", "l": "cell-cell adhesion involved in sealing an epithelial fold", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001050", "l": "negative regulation of tendon cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904219", "l": "positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000028", "l": "regulation of photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of photoperiodism, flowering."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031643", "l": "positive regulation of myelination", "d": ["Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021850", "l": "subpallium glioblast cell division", "d": ["The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046160", "l": "heme a metabolic process", "d": ["The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046067", "l": "dGDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021678", "l": "third ventricle development", "d": ["The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007111", "l": "meiosis II cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904107", "l": "protein localization to microvillus membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a microvillus membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903056", "l": "regulation of melanosome organization", "d": ["Any process that modulates the frequency, rate or extent of melanosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.236426385580998", "identifiers": [{"i": "GO:0042391", "l": "regulation of membrane potential", "d": ["Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:2000756", "l": "regulation of peptidyl-lysine acetylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000743", "l": "negative regulation of anterior head development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140027", "l": "contractile vacuole localization", "d": ["The directed movement of the contractile vacuole to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060922", "l": "atrioventricular node cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001010", "l": "negative regulation of plant-type cell wall cellulose biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072157", "l": "epithelial cell migration involved in distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014876", "l": "response to injury involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.200525186403624", "identifiers": [{"i": "GO:0050954", "l": "sensory perception of mechanical stimulus", "d": ["The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002622", "l": "regulation of B cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150177", "l": "negative regulation of phosphatidylethanolamine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903544", "l": "response to butyrate", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902429", "l": "positive regulation of water channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of water channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071639", "l": "positive regulation of monocyte chemotactic protein-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048776", "l": "negative regulation of leucophore differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046927", "l": "peptidyl-threonine racemization", "d": ["The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904326", "l": "negative regulation of circadian sleep/wake cycle, wakefulness", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901158", "l": "neomycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of neomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033686", "l": "positive regulation of luteinizing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0016574", "l": "histone ubiquitination", "d": ["The modification of histones by addition of ubiquitin groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048480", "l": "stigma development", "d": ["The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002665", "l": "negative regulation of T cell tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007302", "l": "nurse cell nucleus anchoring", "d": ["Attachment of the nurse cell nucleus to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018272", "l": "protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine", "d": ["The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090044", "l": "positive regulation of tubulin deacetylation", "d": ["Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002365", "l": "gamma-delta T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034276", "l": "kynurenic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0097305", "l": "response to alcohol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006171", "l": "cAMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002918", "l": "negative regulation of peripheral B cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009135", "l": "purine nucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010072", "l": "primary shoot apical meristem specification", "d": ["The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042452", "l": "deoxyguanosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075018", "l": "positive regulation of appressorium formation", "d": ["Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904597", "l": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0002653", "l": "negative regulation of tolerance induction dependent upon immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000736", "l": "double-strand break repair via single-strand annealing, removal of nonhomologous ends", "d": ["During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.969489883774216", "identifiers": [{"i": "GO:0061007", "l": "hepaticobiliary system process", "d": ["An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071410", "l": "cellular response to cyclopentenone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061430", "l": "bone trabecula morphogenesis", "d": ["The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072020", "l": "proximal straight tubule development", "d": ["The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904752", "l": "regulation of vascular associated smooth muscle cell migration", "d": ["Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072744", "l": "cellular response to trichodermin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0015011", "l": "nickel-tetrapyrrole coenzyme metabolic process", "d": ["The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060275", "l": "maintenance of stationary phase in response to starvation", "d": ["The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901343", "l": "negative regulation of vasculature development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0006695", "l": "cholesterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990878", "l": "cellular response to gastrin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0110118", "l": "negative regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050935", "l": "iridophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1990840", "l": "response to lectin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003293", "l": "heart valve cell differentiation", "d": ["The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007313", "l": "maternal specification of dorsal/ventral axis, oocyte, soma encoded", "d": ["Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048331", "l": "axial mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090131", "l": "mesenchyme migration", "d": ["The process in which the population of cells that make up a mesenchyme undergo directed movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045146", "l": "initiation of acetate catabolic process by acetate", "d": ["The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.752564210074205", "identifiers": [{"i": "GO:0006399", "l": "tRNA metabolic process", "d": ["The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034233", "l": "regulation of cell wall chitin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140884", "l": "suppression by virus of host type II interferon-mediated signaling pathway", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000723", "l": "negative regulation of cardiac vascular smooth muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003059", "l": "positive regulation of the force of heart contraction by epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001752", "l": "compound eye photoreceptor fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010766", "l": "negative regulation of sodium ion transport", "d": ["Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000668", "l": "regulation of dendritic cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035426", "l": "extracellular matrix-cell signaling", "d": ["Any process that mediates the transfer of information between the extracellular matrix and a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002468", "l": "dendritic cell antigen processing and presentation", "d": ["The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0021535", "l": "cell migration in hindbrain", "d": ["The orderly movement of a cell that will reside in the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072728", "l": "response to Gentian violet", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002355", "l": "detection of tumor cell", "d": ["The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900917", "l": "regulation of octadecene metabolic process", "d": ["Any process that modulates the frequency, rate or extent of octadecene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0090090", "l": "negative regulation of canonical Wnt signaling pathway", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061950", "l": "negative regulation of premature acrosome loss", "d": ["Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.340239173509978", "identifiers": [{"i": "GO:0140352", "l": "export from cell", "d": ["The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032786", "l": "positive regulation of DNA-templated transcription, elongation", "d": ["Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046924", "l": "peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine", "d": ["The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000730", "l": "regulation of termination of RNA polymerase I transcription", "d": ["Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021792", "l": "chemoattraction of branchiomotor axon", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0035822", "l": "gene conversion", "d": ["A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:1902116", "l": "negative regulation of organelle assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1901623", "l": "regulation of lymphocyte chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008205", "l": "ecdysone metabolic process", "d": ["The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000556", "l": "positive regulation of T-helper 1 cell cytokine production", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000204", "l": "negative regulation of ribosomal large subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021989", "l": "olfactory cortex development", "d": ["The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035029", "l": "dorsal closure, leading edge cell fate commitment", "d": ["The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061738", "l": "late endosomal microautophagy", "d": ["The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000196", "l": "positive regulation of female gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of female gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990641", "l": "response to iron ion starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072479", "l": "response to mitotic cell cycle spindle assembly checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:1903828", "l": "negative regulation of protein localization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062143", "l": "L-propargylglycine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046882", "l": "negative regulation of follicle-stimulating hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098737", "l": "protein insertion into plasma membrane", "d": ["The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900407", "l": "regulation of cellular response to oxidative stress", "d": ["Any process that modulates the frequency, rate or extent of cellular response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0045433", "l": "male courtship behavior, veined wing generated song production", "d": ["The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0001658", "l": "branching involved in ureteric bud morphogenesis", "d": ["The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032905", "l": "transforming growth factor beta1 production", "d": ["The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905918", "l": "regulation of CoA-transferase activity", "d": ["Any process that modulates the frequency, rate or extent of CoA-transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000071", "l": "regulation of defense response by callose deposition", "d": ["Any process that modulates the frequency, rate or extent of defense response by callose deposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021669", "l": "rhombomere 6 formation", "d": ["The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903424", "l": "fluoride transmembrane transport", "d": ["The process in which fluoride is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060242", "l": "contact inhibition", "d": ["The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.888616052091592", "identifiers": [{"i": "GO:0002200", "l": "somatic diversification of immune receptors", "d": ["The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060697", "l": "positive regulation of phospholipid catabolic process", "d": ["Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0044491", "l": "positive regulation of molecular function in another organism", "d": ["Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0008315", "l": "G2/MI transition of meiotic cell cycle", "d": ["The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1903524", "l": "positive regulation of blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.7322052342289", "identifiers": [{"i": "GO:0021675", "l": "nerve development", "d": ["The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:1902850", "l": "microtubule cytoskeleton organization involved in mitosis", "d": ["Any microtubule cytoskeleton organization that is involved in mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035366", "l": "negative regulation of thymine transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0090487", "l": "secondary metabolite catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043248", "l": "proteasome assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140060", "l": "axon arborization", "d": ["The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990548", "l": "mitochondrial FAD transmembrane transport", "d": ["The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019715", "l": "peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid", "d": ["The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0061912", "l": "selective autophagy", "d": ["The macroautophagy process in which specific structures are targeted by the autophagy process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021504", "l": "neural fold hinge point formation", "d": ["The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.721054312086878", "identifiers": [{"i": "GO:0042552", "l": "myelination", "d": ["The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.04413933979864", "identifiers": [{"i": "GO:0031329", "l": "regulation of cellular catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.928990792433112", "identifiers": [{"i": "GO:0090567", "l": "reproductive shoot system development", "d": ["The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140651", "l": "futile creatine cycle", "d": ["The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000727", "l": "positive regulation of cardiac muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060126", "l": "somatotropin secreting cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035063", "l": "nuclear speck organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032332", "l": "positive regulation of chondrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099639", "l": "neurotransmitter receptor transport, endosome to plasma membrane", "d": ["The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035153", "l": "epithelial cell type specification, open tracheal system", "d": ["Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905640", "l": "response to acetaldehyde", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070149", "l": "mitochondrial glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033347", "l": "tetrose metabolic process", "d": ["The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043331", "l": "response to dsRNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099554", "l": "trans-synaptic signaling by soluble gas, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000436", "l": "positive regulation of protein neddylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein neddylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003145", "l": "embryonic heart tube formation via epithelial folding", "d": ["The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000485", "l": "regulation of glutamine transport", "d": ["Any process that modulates the frequency, rate or extent of glutamine transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000412", "l": "histone peptidyl-prolyl isomerization", "d": ["The modification of a histone by cis-trans isomerization of a proline residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097064", "l": "ncRNA export from nucleus", "d": ["The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071800", "l": "podosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000765", "l": "response to pheromone regulating pheromone-induced unidirectional conjugation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045061", "l": "thymic T cell selection", "d": ["The process of T cell selection that occurs in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007496", "l": "anterior midgut development", "d": ["The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902166", "l": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098784", "l": "biofilm matrix organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046518", "l": "octamethylcyclotetrasiloxane metabolic process", "d": ["The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010090", "l": "trichome morphogenesis", "d": ["The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035016", "l": "elongation of arista lateral", "d": ["The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903573", "l": "negative regulation of response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900616", "l": "emericellamide A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000938", "l": "positive regulation of cellotriose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901550", "l": "regulation of endothelial cell development", "d": ["Any process that modulates the frequency, rate or extent of endothelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032923", "l": "organic phosphonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0034698", "l": "response to gonadotropin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032967", "l": "positive regulation of collagen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072281", "l": "mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055016", "l": "hypochord development", "d": ["The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009407", "l": "toxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0086047", "l": "membrane depolarization during Purkinje myocyte cell action potential", "d": ["The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0021536", "l": "diencephalon development", "d": ["The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902698", "l": "pentose catabolic process to butyrate", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to butyrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010114", "l": "response to red light", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010054", "l": "trichoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090320", "l": "regulation of chylomicron remnant clearance", "d": ["Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021764", "l": "amygdala development", "d": ["The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060266", "l": "negative regulation of respiratory burst involved in inflammatory response", "d": ["Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901984", "l": "negative regulation of protein acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061120", "l": "regulation of positive chemotaxis to cAMP by DIF-1", "d": ["Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071701", "l": "regulation of MAPK export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904347", "l": "regulation of small intestine smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:1901658", "l": "glycosyl compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosyl compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090297", "l": "positive regulation of mitochondrial DNA replication", "d": ["Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002879", "l": "positive regulation of acute inflammatory response to non-antigenic stimulus", "d": ["Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021508", "l": "floor plate formation", "d": ["The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0031018", "l": "endocrine pancreas development", "d": ["The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0007293", "l": "germarium-derived egg chamber formation", "d": ["Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042509", "l": "regulation of tyrosine phosphorylation of STAT protein", "d": ["Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090668", "l": "endothelial cell chemotaxis to vascular endothelial growth factor", "d": ["The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046493", "l": "lipid A metabolic process", "d": ["The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0045666", "l": "positive regulation of neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097704", "l": "cellular response to oscillatory fluid shear stress", "d": ["Any response to oscillatory fluid shear stress that occurs at the level of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0052031", "l": "modulation by symbiont of host defense response", "d": ["Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046314", "l": "phosphocreatine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032750", "l": "positive regulation of interleukin-26 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-26 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120154", "l": "negative regulation of ERBB4 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062097", "l": "chemosynthesis", "d": ["The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019672", "l": "ethanol-acetate fermentation to butyrate and caproate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036300", "l": "B cell receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016131", "l": "brassinosteroid metabolic process", "d": ["The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006437", "l": "tyrosyl-tRNA aminoacylation", "d": ["The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043055", "l": "maintenance of dauer", "d": ["Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036340", "l": "chitin-based cuticle sclerotization by biomineralization", "d": ["The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902948", "l": "negative regulation of tau-protein kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048792", "l": "spontaneous exocytosis of neurotransmitter", "d": ["The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000007", "l": "negative regulation of metanephric comma-shaped body morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000133", "l": "positive regulation of tyramine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006058", "l": "mannoprotein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140298", "l": "endocytic iron import into cell", "d": ["Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.75272396535307", "identifiers": [{"i": "GO:0035282", "l": "segmentation", "d": ["The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903010", "l": "regulation of bone development", "d": ["Any process that modulates the frequency, rate or extent of bone development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046880", "l": "regulation of follicle-stimulating hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0075009", "l": "germ tube formation", "d": ["Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051933", "l": "amino acid neurotransmitter reuptake", "d": ["The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051940", "l": "regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032244", "l": "positive regulation of nucleoside transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0034440", "l": "lipid oxidation", "d": ["The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990349", "l": "gap junction-mediated intercellular transport", "d": ["The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046065", "l": "dCTP metabolic process", "d": ["The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0060512", "l": "prostate gland morphogenesis", "d": ["The process in which the anatomical structures of a prostate gland are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061975", "l": "articular cartilage development", "d": ["The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.833593486544025", "identifiers": [{"i": "GO:0043207", "l": "response to external biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007621", "l": "negative regulation of female receptivity", "d": ["Any process that stops, prevents or reduces the receptiveness of a female to male advances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140384", "l": "metacyclogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010361", "l": "regulation of anion channel activity by blue light", "d": ["Any process in which blue light modulates the frequency, rate or extent of anion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903256", "l": "selenoneine metabolic process", "d": ["The chemical reactions and pathways involving selenoneine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030847", "l": "termination of RNA polymerase II transcription, exosome-dependent", "d": ["The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0086043", "l": "bundle of His cell action potential", "d": ["An action potential that occurs in a bundle of His cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030963", "l": "peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine", "d": ["The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900118", "l": "negative regulation of execution phase of apoptosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070945", "l": "neutrophil-mediated killing of gram-negative bacterium", "d": ["The directed killing of a gram-negative bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010138", "l": "pyrimidine ribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010827", "l": "regulation of glucose transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055009", "l": "atrial cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structure of cardiac atrium muscle is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050936", "l": "xanthophore differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019584", "l": "galactonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900213", "l": "positive regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0008343", "l": "adult feeding behavior", "d": ["Feeding behavior in a fully developed and mature organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903847", "l": "regulation of aorta morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of aorta morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0002237", "l": "response to molecule of bacterial origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0015721", "l": "bile acid and bile salt transport", "d": ["The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045728", "l": "respiratory burst after phagocytosis", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035543", "l": "positive regulation of SNARE complex assembly", "d": ["Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071314", "l": "cellular response to cocaine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045479", "l": "vesicle targeting to fusome", "d": ["The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.052146566951166", "identifiers": [{"i": "GO:0022607", "l": "cellular component assembly", "d": ["The aggregation, arrangement and bonding together of a cellular component."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007294", "l": "germarium-derived oocyte fate determination", "d": ["The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140958", "l": "target-directed miRNA degradation", "d": ["The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1902486", "l": "protein localization to growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a growing cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061295", "l": "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060556", "l": "regulation of vitamin D biosynthetic process", "d": ["Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046417", "l": "chorismate metabolic process", "d": ["The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001087", "l": "sophorose transport", "d": ["The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032906", "l": "transforming growth factor beta2 production", "d": ["The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051889", "l": "negative regulation of timing of exogen", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034586", "l": "21U-RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140543", "l": "positive regulation of piRNA transcription", "d": ["Any process that increases the frequency, rate or extent of the synthesis of piRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0032271", "l": "regulation of protein polymerization", "d": ["Any process that modulates the frequency, rate or extent of the process of creating protein polymers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046338", "l": "phosphatidylethanolamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.198535815504115", "identifiers": [{"i": "GO:0008284", "l": "positive regulation of cell population proliferation", "d": ["Any process that activates or increases the rate or extent of cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901907", "l": "diadenosine pentaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032830", "l": "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032594", "l": "protein transport within lipid bilayer", "d": ["The directed movement of a protein from one location to another within a lipid bilayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072242", "l": "metanephric DCT cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070483", "l": "detection of hypoxia", "d": ["The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061847", "l": "response to cholecystokinin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019761", "l": "glucosinolate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903516", "l": "regulation of single strand break repair", "d": ["Any process that modulates the frequency, rate or extent of single strand break repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010065", "l": "primary meristem tissue development", "d": ["The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904691", "l": "negative regulation of type B pancreatic cell proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010375", "l": "stomatal complex patterning", "d": ["The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036392", "l": "chemokine (C-C motif) ligand 20 production", "d": ["The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060938", "l": "epicardium-derived cardiac fibroblast cell differentiation", "d": ["The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901853", "l": "5,6,7,8-tetrahydrosarcinapterin metabolic process", "d": ["The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006011", "l": "UDP-glucose metabolic process", "d": ["The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061413", "l": "regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source", "d": ["A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018032", "l": "protein amidation", "d": ["Addition of an amide group from a glycine to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048765", "l": "root hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a root hair cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0042659", "l": "regulation of cell fate specification", "d": ["Any process that mediates the adoption of a specific fate by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061137", "l": "bud dilation", "d": ["The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003370", "l": "cell-cell adhesion involved in mesendodermal cell migration", "d": ["The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099641", "l": "anterograde axonal protein transport", "d": ["The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010032", "l": "meiotic chromosome condensation", "d": ["Compaction of chromatin structure prior to meiosis in eukaryotic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048559", "l": "establishment of floral organ orientation", "d": ["The process that determines the orientation of the floral organs with reference to the central axis of the flower."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099545", "l": "trans-synaptic signaling by trans-synaptic complex", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006080", "l": "substituted mannan metabolic process", "d": ["The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900206", "l": "regulation of pronephric nephron tubule development", "d": ["Any process that modulates the frequency, rate or extent of pronephric nephron tubule development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033529", "l": "raffinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002321", "l": "natural killer cell progenitor differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000811", "l": "negative regulation of anoikis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anoikis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900024", "l": "regulation of substrate adhesion-dependent cell spreading", "d": ["Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006787", "l": "porphyrin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0086070", "l": "SA node cell to atrial cardiac muscle cell communication", "d": ["The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0042752", "l": "regulation of circadian rhythm", "d": ["Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.615524802961822", "identifiers": [{"i": "GO:0006119", "l": "oxidative phosphorylation", "d": ["The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019271", "l": "aerobactin transport", "d": ["The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901563", "l": "response to camptothecin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043636", "l": "bisphenol A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990019", "l": "protein storage vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061764", "l": "late endosome to lysosome transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016487", "l": "farnesol metabolic process", "d": ["The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009093", "l": "cysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901188", "l": "negative regulation of ephrin receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045219", "l": "regulation of FasL production", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010094", "l": "specification of carpel identity", "d": ["The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036111", "l": "very long-chain fatty-acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.831061310706126", "identifiers": [{"i": "GO:0044283", "l": "small molecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0097028", "l": "dendritic cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009827", "l": "plant-type cell wall modification", "d": ["The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032026", "l": "response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099016", "l": "evasion by virus of DNA end degradation", "d": ["A process by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900884", "l": "regulation of tridecane biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0048916", "l": "posterior lateral line development", "d": ["The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033228", "l": "cysteine export across plasma membrane", "d": ["The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106220", "l": "pyocyanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046154", "l": "rhodopsin metabolic process", "d": ["The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904382", "l": "mannose trimming involved in glycoprotein ERAD pathway", "d": ["The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033384", "l": "geranyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of geranyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901023", "l": "4-hydroxyphenylacetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046844", "l": "chorion micropyle formation", "d": ["Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031916", "l": "regulation of synaptic metaplasticity", "d": ["A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903560", "l": "3-cyano-L-alanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.703977263494721", "identifiers": [{"i": "GO:0030031", "l": "cell projection assembly", "d": ["Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0060760", "l": "positive regulation of response to cytokine stimulus", "d": ["Any process that increases the rate, frequency, or extent of a response to cytokine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.411236363514533", "identifiers": [{"i": "GO:0051172", "l": "negative regulation of nitrogen compound metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043382", "l": "positive regulation of memory T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of memory T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.357135392541679", "identifiers": [{"i": "GO:0048437", "l": "floral organ development", "d": ["The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042427", "l": "serotonin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010718", "l": "positive regulation of epithelial to mesenchymal transition", "d": ["Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900115", "l": "extracellular regulation of signal transduction", "d": ["Any regulation of signal transduction that takes place in the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902729", "l": "negative regulation of proteoglycan biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120163", "l": "negative regulation of cold-induced thermogenesis", "d": ["Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904057", "l": "negative regulation of sensory perception of pain", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032739", "l": "positive regulation of interleukin-16 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-16 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.182134323627913", "identifiers": [{"i": "GO:0050911", "l": "detection of chemical stimulus involved in sensory perception of smell", "d": ["The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033528", "l": "S-methylmethionine cycle", "d": ["A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099574", "l": "regulation of protein catabolic process at synapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating protein degradation at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904618", "l": "positive regulation of actin binding", "d": ["Any process that activates or increases the frequency, rate or extent of actin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0051453", "l": "regulation of intracellular pH", "d": ["Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902135", "l": "(+)-secoisolariciresinol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.152093828606723", "identifiers": [{"i": "GO:0000819", "l": "sister chromatid segregation", "d": ["The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072671", "l": "mitochondria-associated ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900514", "l": "positive regulation of starch utilization system complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0065004", "l": "protein-DNA complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0009807", "l": "lignan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061294", "l": "mesonephric renal vesicle induction", "d": ["Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0072384", "l": "organelle transport along microtubule", "d": ["The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031043", "l": "O-glycan processing, core 7", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033504", "l": "floor plate development", "d": ["The progression of the floor plate over time from its initial formation until its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045064", "l": "T-helper 2 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002264", "l": "endothelial cell activation involved in immune response", "d": ["A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090062", "l": "regulation of trehalose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0016266", "l": "O-glycan processing", "d": ["The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090546", "l": "chlorophyll fluorescence", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032832", "l": "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038175", "l": "negative regulation of SREBP signaling pathway in response to increased oxygen levels", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2000771", "l": "positive regulation of establishment or maintenance of cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070479", "l": "nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001516", "l": "prostaglandin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902831", "l": "positive regulation of spinal cord association neuron differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.850331132069329", "identifiers": [{"i": "GO:0048583", "l": "regulation of response to stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048246", "l": "macrophage chemotaxis", "d": ["The movement of a macrophage in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031848", "l": "protection from non-homologous end joining at telomere", "d": ["A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090254", "l": "cell elongation involved in imaginal disc-derived wing morphogenesis", "d": ["The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046086", "l": "adenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150018", "l": "basal dendrite development", "d": ["The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030813", "l": "positive regulation of nucleotide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071606", "l": "chemokine (C-C motif) ligand 4 production", "d": ["The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901579", "l": "positive regulation of alkane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009744", "l": "response to sucrose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046361", "l": "2-oxobutyrate metabolic process", "d": ["The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075244", "l": "regulation of oospore formation", "d": ["Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010266", "l": "response to vitamin B1", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043974", "l": "histone H3-K27 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019313", "l": "allose metabolic process", "d": ["The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033060", "l": "ocellus pigmentation", "d": ["The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085019", "l": "formation of tubovesicular network for nutrient acquisition", "d": ["The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160027", "l": "egg deposition", "d": ["The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015941", "l": "pantothenate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019073", "l": "viral DNA genome packaging", "d": ["The packing of viral DNA into a capsid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990747", "l": "pancreatic trypsinogen secretion", "d": ["The regulated release of trypsinogen from the cells of the exocrine pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048677", "l": "axon extension involved in regeneration", "d": ["Long distance growth of a single axon process involved in regeneration of the neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901003", "l": "negative regulation of fermentation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fermentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000239", "l": "pachytene", "d": ["The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051639", "l": "actin filament network formation", "d": ["The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042442", "l": "melatonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071853", "l": "fungal-type cell wall disassembly", "d": ["A cellular process that results in the breakdown of a fungal-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060781", "l": "mesenchymal cell proliferation involved in prostate gland development", "d": ["The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140515", "l": "mitotic nuclear bridge organization", "d": ["A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048625", "l": "myoblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070800", "l": "negative regulation of conidiophore stalk development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018186", "l": "peroxidase-heme linkage", "d": ["The covalent linkage of heme to peroxidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900648", "l": "positive regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015737", "l": "galacturonate transmembrane transport", "d": ["The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060141", "l": "positive regulation of syncytium formation by virus", "d": ["The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000893", "l": "cellotriose metabolic process", "d": ["The chemical reactions and pathways involving a cellotriose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002728", "l": "negative regulation of natural killer cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046157", "l": "siroheme catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904048", "l": "regulation of spontaneous neurotransmitter secretion", "d": ["Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140467", "l": "integrated stress response signaling", "d": ["The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:1902645", "l": "tertiary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tertiary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904159", "l": "megasporocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043383", "l": "negative T cell selection", "d": ["The process of elimination of immature T cells which react strongly with self-antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0015750", "l": "pentose transmembrane transport", "d": ["The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000333", "l": "negative regulation of blood microparticle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902804", "l": "negative regulation of synaptic vesicle transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0021533", "l": "cell differentiation in hindbrain", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044473", "l": "envenomation resulting in negative regulation of calcium channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097680", "l": "double-strand break repair via classical nonhomologous end joining", "d": ["An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905687", "l": "regulation of diacylglycerol kinase activity", "d": ["Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045209", "l": "MAPK phosphatase export from nucleus, leptomycin B sensitive", "d": ["Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.029089830461487", "identifiers": [{"i": "GO:0035239", "l": "tube morphogenesis", "d": ["The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090515", "l": "L-glutamate transmembrane import into vacuole", "d": ["The directed movement of L-glutamate into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052154", "l": "perturbation of host B-cell mediated immune response", "d": ["A process in which an organism effects a change that affects the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045797", "l": "positive regulation of intestinal cholesterol absorption", "d": ["Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.401997675337611", "identifiers": [{"i": "GO:0032880", "l": "regulation of protein localization", "d": ["Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070673", "l": "response to interleukin-18", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905405", "l": "regulation of mitotic cohesin loading", "d": ["Any process that modulates the frequency, rate or extent of mitotic cohesin loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140676", "l": "oscillatory cAMP signaling", "d": ["Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030576", "l": "Cajal body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009772", "l": "photosynthetic electron transport in photosystem II", "d": ["A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905193", "l": "negative regulation of chloroplast fission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007542", "l": "primary sex determination, germ-line", "d": ["The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018213", "l": "peptidyl-valine modification", "d": ["The modification of peptidyl-valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015692", "l": "lead ion transport", "d": ["The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000256", "l": "positive regulation of male germ cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of male germ cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061643", "l": "chemorepulsion of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031153", "l": "slug development involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002589", "l": "regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019248", "l": "D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde", "d": ["The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905150", "l": "regulation of voltage-gated sodium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033189", "l": "response to vitamin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031948", "l": "positive regulation of glucocorticoid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120060", "l": "regulation of gastric emptying", "d": ["Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060165", "l": "regulation of timing of subpallium neuron differentiation", "d": ["The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061226", "l": "proximal/distal pattern formation involved in mesonephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000818", "l": "negative regulation of myoblast proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021931", "l": "rostral hindbrain neuronal precursor cell proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0021795", "l": "cerebral cortex cell migration", "d": ["The orderly movement of cells from one site to another in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901840", "l": "negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051221", "l": "tungsten incorporation into metallo-sulfur cluster", "d": ["The incorporation of tungsten into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034342", "l": "response to type III interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043320", "l": "natural killer cell degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033030", "l": "negative regulation of neutrophil apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000033", "l": "regulation of seed dormancy process", "d": ["Any process that modulates the frequency, rate or extent of seed dormancy process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901744", "l": "2-deoxystreptamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060776", "l": "simple leaf morphogenesis", "d": ["The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043362", "l": "nucleate erythrocyte maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050666", "l": "regulation of homocysteine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015715", "l": "nucleotide-sulfate transport", "d": ["The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060222", "l": "regulation of retinal cone cell fate commitment", "d": ["Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0051961", "l": "negative regulation of nervous system development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021771", "l": "lateral geniculate nucleus development", "d": ["The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045016", "l": "mitochondrial magnesium ion transmembrane transport", "d": ["The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035763", "l": "dorsal motor nucleus of vagus nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900591", "l": "violaceol II metabolic process", "d": ["The chemical reactions and pathways involving violaceol II."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0021766", "l": "hippocampus development", "d": ["The progression of the hippocampus over time from its initial formation until its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010268", "l": "brassinosteroid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043516", "l": "regulation of DNA damage response, signal transduction by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090161", "l": "Golgi ribbon formation", "d": ["The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070897", "l": "transcription preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903594", "l": "negative regulation of histamine secretion by mast cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033552", "l": "response to vitamin B3", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902633", "l": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007078", "l": "lamin depolymerization", "d": ["The cell cycle process in which lamin is depolymerized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904134", "l": "negative regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002480", "l": "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0019229", "l": "regulation of vasoconstriction", "d": ["Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120207", "l": "endocytosis, site selection", "d": ["The process of selecting and or marking the position where endocytosis will occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.652206388559449", "identifiers": [{"i": "GO:0007565", "l": "female pregnancy", "d": ["The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903165", "l": "response to polycyclic arene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046133", "l": "pyrimidine ribonucleoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052786", "l": "alpha-linked polysaccharide catabolism to maltotriose", "d": ["The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000480", "l": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070193", "l": "synaptonemal complex organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903905", "l": "positive regulation of establishment of T cell polarity", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071483", "l": "cellular response to blue light", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010724", "l": "regulation of definitive erythrocyte differentiation", "d": ["Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140247", "l": "protein catabolic process at presynapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098914", "l": "membrane repolarization during atrial cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0060759", "l": "regulation of response to cytokine stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0007612", "l": "learning", "d": ["Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0055117", "l": "regulation of cardiac muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000022", "l": "regulation of jasmonic acid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038012", "l": "negative regulation of Wnt signaling pathway by Wnt receptor internalization", "d": ["Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000344", "l": "positive regulation of acrosome reaction", "d": ["Any process that activates or increases the frequency, rate or extent of the acrosome reaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002325", "l": "natural killer cell differentiation involved in immune response", "d": ["The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035216", "l": "haltere disc development", "d": ["Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0021955", "l": "central nervous system neuron axonogenesis", "d": ["Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032023", "l": "trypsinogen activation", "d": ["The proteolytic processing of trypsinogen to the active form, trypsin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010235", "l": "guard mother cell cytokinesis", "d": ["The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903438", "l": "positive regulation of mitotic cytokinetic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015782", "l": "CMP-N-acetylneuraminate transmembrane transport", "d": ["The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043448", "l": "alkane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099183", "l": "trans-synaptic signaling by BDNF, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072649", "l": "interferon-kappa production", "d": ["The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900086", "l": "positive regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990268", "l": "response to gold nanoparticle", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904038", "l": "regulation of iron export across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036052", "l": "protein localization to uropod", "d": ["A process in which a protein is transported to, or maintained in, a uropod. 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Interferon-gamma is also known as type II interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905467", "l": "positive regulation of G-quadruplex DNA unwinding", "d": ["Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900718", "l": "positive regulation of violaceol II biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036339", "l": "lymphocyte adhesion to endothelial cell of high endothelial venule", "d": ["The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0099136", "l": "chimeric non-reproductive fruiting body development", "d": ["Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032595", "l": "B cell receptor transport within lipid bilayer", "d": ["The directed movement of a B cell receptor within a lipid bilayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048261", "l": "negative regulation of receptor-mediated endocytosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904333", "l": "positive regulation of error-prone translesion synthesis", "d": ["Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018401", "l": "peptidyl-proline hydroxylation to 4-hydroxy-L-proline", "d": ["The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051877", "l": "pigment granule aggregation in cell center", "d": ["The directed movement of dispersed pigment granules towards the center of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080128", "l": "anther septum development", "d": ["The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0001776", "l": "leukocyte homeostasis", "d": ["The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051674", "l": "localization of cell", "d": ["Any process in which a cell is transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070476", "l": "rRNA (guanine-N7)-methylation", "d": ["The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048716", "l": "labrum morphogenesis", "d": ["The process in which the anatomical structures of labrum are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090200", "l": "positive regulation of release of cytochrome c from mitochondria", "d": ["Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000349", "l": "generation of catalytic spliceosome for first transesterification step", "d": ["Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001094", "l": "xylotriose transport", "d": ["The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903445", "l": "protein transport from ciliary membrane to plasma membrane", "d": ["The directed movement of protein from ciliary membrane to plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072252", "l": "metanephric juxtaglomerulus cell development", "d": ["The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0045136", "l": "development of secondary sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:1903305", "l": "regulation of regulated secretory pathway", "d": ["Any process that modulates the frequency, rate or extent of regulated secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901706", "l": "mesenchymal cell differentiation involved in bone development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071333", "l": "cellular response to glucose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045337", "l": "farnesyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of farnesyl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021870", "l": "Cajal-Retzius cell differentiation", "d": ["The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000279", "l": "negative regulation of DNA biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070605", "l": "regulation of (1->3)-alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903418", "l": "protein localization to plasma membrane of cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033140", "l": "negative regulation of peptidyl-serine phosphorylation of STAT protein", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900877", "l": "nonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nonadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1902807", "l": "negative regulation of cell cycle G1/S phase transition", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902647", "l": "negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099009", "l": "viral genome circularization", "d": ["The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.990212222697807", "identifiers": [{"i": "GO:0009892", "l": "negative regulation of metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903112", "l": "positive regulation of single-strand break repair via homologous recombination", "d": ["Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120302", "l": "background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001192", "l": "negative regulation of gamma-delta T cell activation involved in immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002534", "l": "cytokine production involved in inflammatory response", "d": ["The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090735", "l": "DNA repair complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097046", "l": "replication fork progression beyond termination site", "d": ["Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003165", "l": "Purkinje myocyte development", "d": ["The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001808", "l": "negative regulation of type IV hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010207", "l": "photosystem II assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043963", "l": "perturbation of host adenylate cyclase-mediated signal transduction", "d": ["A process in which a symbiont alters or subverts an adenylate cyclase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903259", "l": "exon-exon junction complex disassembly", "d": ["The disaggregation of an exon-exon junction complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902445", "l": "regulation of mitochondrial membrane permeability involved in programmed necrotic cell death", "d": ["Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035509", "l": "negative regulation of myosin-light-chain-phosphatase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044416", "l": "induction by symbiont of host defense response", "d": ["The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0071624", "l": "positive regulation of granulocyte chemotaxis", "d": ["Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0051931", "l": "regulation of sensory perception", "d": ["Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046328", "l": "regulation of JNK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032641", "l": "lymphotoxin A production", "d": ["The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051085", "l": "chaperone cofactor-dependent protein refolding", "d": ["The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061063", "l": "positive regulation of nematode larval development", "d": ["Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0009190", "l": "cyclic nucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051131", "l": "chaperone-mediated protein complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0021846", "l": "cell proliferation in forebrain", "d": ["The creation of greater cell numbers in the forebrain due to cell division of progenitor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051966", "l": "regulation of synaptic transmission, glutamatergic", "d": ["Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0070601", "l": "centromeric sister chromatid cohesion", "d": ["The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046051", "l": "UTP metabolic process", "d": ["The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046741", "l": "transport of virus in host, tissue to tissue", "d": ["The transport of a virus between tissues in a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052783", "l": "reuteran metabolic process", "d": ["The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031425", "l": "chloroplast RNA processing", "d": ["The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001574", "l": "ganglioside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045670", "l": "regulation of osteoclast differentiation", "d": ["Any process that modulates the frequency, rate or extent of osteoclast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007221", "l": "positive regulation of transcription of Notch receptor target", "d": ["The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019474", "l": "L-lysine catabolic process to acetyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045223", "l": "regulation of CD4 production", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046471", "l": "phosphatidylglycerol metabolic process", "d": ["The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080167", "l": "response to karrikin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0014889", "l": "muscle atrophy", "d": ["A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098532", "l": "histone H3-K27 trimethylation", "d": ["The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035202", "l": "tracheal pit formation in open tracheal system", "d": ["Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900630", "l": "methanophenazine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methanophenazine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061132", "l": "pancreas induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072103", "l": "glomerulus vasculature morphogenesis", "d": ["The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0001706", "l": "endoderm formation", "d": ["The formation of the endoderm during gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904271", "l": "L-proline import across plasma membrane", "d": ["The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061308", "l": "cardiac neural crest cell development involved in heart development", "d": ["The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001146", "l": "positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905621", "l": "positive regulation of alpha-(1->3)-fucosyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030157", "l": "pancreatic juice secretion", "d": ["The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006719", "l": "juvenile hormone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097397", "l": "cellular response to interleukin-32", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007489", "l": "maintenance of imaginal histoblast diploidy", "d": ["The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002300", "l": "CD8-positive, alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014858", "l": "positive regulation of skeletal muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071301", "l": "cellular response to vitamin B1", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098884", "l": "postsynaptic neurotransmitter receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900058", "l": "regulation of sulfate assimilation", "d": ["Any process that modulates the frequency, rate or extent of sulfate assimilation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905867", "l": "epididymis development", "d": ["The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048586", "l": "regulation of long-day photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:1905777", "l": "regulation of exonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of exonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052062", "l": "induction by symbiont of host phytoalexin production", "d": ["The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0106014", "l": "regulation of inflammatory response to wounding", "d": ["Any process that modulates the frequency, rate or extent of the inflammatory response to wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.665902432881424", "identifiers": [{"i": "GO:0009308", "l": "amine metabolic process", "d": ["The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003114", "l": "positive regulation of heart rate by circulating norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000434", "l": "regulation of protein neddylation", "d": ["Any process that modulates the frequency, rate or extent of protein neddylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043363", "l": "nucleate erythrocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000627", "l": "positive regulation of miRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of miRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016204", "l": "determination of muscle attachment site", "d": ["The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902366", "l": "regulation of Notch signaling pathway involved in somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098790", "l": "ncRNA transcription associated with protein coding gene TSS/TES", "d": ["The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006210", "l": "thymine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900556", "l": "emericellamide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071726", "l": "cellular response to diacyl bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061143", "l": "alveolar primary septum development", "d": ["The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903656", "l": "regulation of type IV pilus biogenesis", "d": ["Any process that modulates the frequency, rate or extent of type IV pilus biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990820", "l": "response to mitotic DNA integrity checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072719", "l": "cellular response to cisplatin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048831", "l": "regulation of shoot system development", "d": ["Any process that modulates the frequency, rate or extent of shoot development."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002369", "l": "T cell cytokine production", "d": ["Any process that contributes to cytokine production by a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044659", "l": "viral release from host cell by cytolysis", "d": ["The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097045", "l": "phosphatidylserine exposure on blood platelet", "d": ["A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0070227", "l": "lymphocyte apoptotic process", "d": ["Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0099541", "l": "trans-synaptic signaling by lipid", "d": ["Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106288", "l": "regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA", "d": ["Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0046552", "l": "photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018912", "l": "1,4-dichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903043", "l": "positive regulation of chondrocyte hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097210", "l": "response to gonadotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071291", "l": "cellular response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034303", "l": "myxospore formation", "d": ["The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052028", "l": "symbiont-mediated activation of host signal transduction pathway", "d": ["A process in which a symbiont subverts a signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048587", "l": "regulation of short-day photoperiodism, flowering", "d": ["Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141044", "l": "epigenetic programming in the endosperm", "d": ["The global programming of epigenetic modifications following binucleate central cell fertilization. This involves DNA methylation at the silent allele. In the endosperm, maternal genomes are hypomethylated compared with the paternal genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900743", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to pH", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061774", "l": "cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903818", "l": "positive regulation of voltage-gated potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045610", "l": "regulation of hemocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of hemocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061735", "l": "DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072284", "l": "metanephric S-shaped body morphogenesis", "d": ["The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032772", "l": "negative regulation of tyrosinase activity", "d": ["Any process that stops or reduces the activity of a tyrosinase enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0097065", "l": "anterior head development", "d": ["The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050813", "l": "epothilone metabolic process", "d": ["The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990109", "l": "rejection of pollen from other species", "d": ["The recognition and rejection of pollen of one species by cells in the stigma of another species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051885", "l": "positive regulation of timing of anagen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099547", "l": "regulation of translation at synapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990643", "l": "cellular response to granulocyte colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010325", "l": "raffinose family oligosaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization)."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0032414", "l": "positive regulation of ion transmembrane transporter activity", "d": ["Any process that activates or increases the activity of an ion transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035353", "l": "nicotinamide mononucleotide transmembrane transport", "d": ["The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032732", "l": "positive regulation of interleukin-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-1 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0042755", "l": "eating behavior", "d": ["The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0009812", "l": "flavonoid metabolic process", "d": ["The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0051175", "l": "negative regulation of sulfur metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016092", "l": "prenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000463", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0031102", "l": "neuron projection regeneration", "d": ["The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0045665", "l": "negative regulation of neuron differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002554", "l": "serotonin secretion by platelet", "d": ["The regulated release of serotonin by a platelet or group of platelets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014837", "l": "myoblast fate determination involved in skeletal muscle regeneration", "d": ["The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070580", "l": "base J metabolic process", "d": ["The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097211", "l": "cellular response to gonadotropin-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046098", "l": "guanine metabolic process", "d": ["The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043647", "l": "inositol phosphate metabolic process", "d": ["The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010402", "l": "pectic arabinan metabolic process", "d": ["The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901118", "l": "cephamycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cephamycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006123", "l": "mitochondrial electron transport, cytochrome c to oxygen", "d": ["The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062172", "l": "lutein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lutein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035566", "l": "regulation of metanephros size", "d": ["Any process that modulates the size of a metanephric kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034275", "l": "kynurenic acid metabolic process", "d": ["The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032329", "l": "serine transport", "d": ["The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0043368", "l": "positive T cell selection", "d": ["The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039016", "l": "cell-cell signaling involved in pronephros development", "d": ["Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903901", "l": "negative regulation of viral life cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042544", "l": "melibiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900198", "l": "positive regulation of penicillin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990680", "l": "response to melanocyte-stimulating hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0051099", "l": "positive regulation of binding", "d": ["Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006727", "l": "ommochrome biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031148", "l": "DIF-1 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902860", "l": "propionyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propionyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043397", "l": "regulation of corticotropin-releasing hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901703", "l": "protein localization involved in auxin polar transport", "d": ["Any protein localization that is involved in auxin polar transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072514", "l": "trehalose transport in response to water deprivation", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075299", "l": "positive regulation of zygospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106225", "l": "peptidyl-lysine 2-hydroxyisobutyrylation", "d": ["The 2-hydroxyisobutyrylation of a lysine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903249", "l": "negative regulation of citrulline biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042342", "l": "cyanogenic glycoside catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000799", "l": "positive regulation of amniotic stem cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046181", "l": "ketogluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140965", "l": "secondary piRNA processing", "d": ["A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010407", "l": "non-classical arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903514", "l": "release of sequestered calcium ion into cytosol by endoplasmic reticulum", "d": ["The directed movement of calcium ion from endoplasmic reticulum to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900614", "l": "F-9775B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of F-9775B."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090016", "l": "regulation of leaflet formation", "d": ["Any process that modulates the frequency, rate or extent of leaflet formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072066", "l": "prebend segment development", "d": ["The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035736", "l": "cell proliferation involved in compound eye morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000860", "l": "positive regulation of aldosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of aldosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036344", "l": "platelet morphogenesis", "d": ["Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070672", "l": "response to interleukin-15", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.45299868619928", "identifiers": [{"i": "GO:0044042", "l": "glucan metabolic process", "d": ["The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019300", "l": "rhamnose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046549", "l": "retinal cone cell development", "d": ["Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0007613", "l": "memory", "d": ["The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061966", "l": "establishment of left/right asymmetry", "d": ["The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0033260", "l": "nuclear DNA replication", "d": ["The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070478", "l": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "d": ["The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060288", "l": "formation of a compartment boundary", "d": ["Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990549", "l": "mitochondrial NAD transmembrane transport", "d": ["The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008363", "l": "larval chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140980", "l": "intracellular nucleoside homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905177", "l": "tracheary element differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044636", "l": "envenomation resulting in modulation of complement activation, classical pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902324", "l": "positive regulation of methyl-branched fatty acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0044088", "l": "regulation of vacuole organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904363", "l": "negative regulation of calcitonin secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070378", "l": "positive regulation of ERK5 cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904446", "l": "positive regulation of establishment of Sertoli cell barrier", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061479", "l": "response to reverse transcriptase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0016075", "l": "rRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0030641", "l": "regulation of cellular pH", "d": ["Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0015886", "l": "heme transport", "d": ["The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021620", "l": "hypoglossal nerve formation", "d": ["The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046482", "l": "para-aminobenzoic acid metabolic process", "d": ["The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0019430", "l": "removal of superoxide radicals", "d": ["Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014852", "l": "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140542", "l": "regulation of piRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of the synthesis of a piRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075120", "l": "symbiont-mediated suppression of host G protein-coupled receptor signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a G protein-coupled receptor signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000644", "l": "regulation of receptor catabolic process", "d": ["Any process that modulates the frequency, rate or extent of receptor catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044211", "l": "CTP salvage", "d": ["Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010344", "l": "seed oilbody biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905341", "l": "negative regulation of protein localization to kinetochore", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900706", "l": "positive regulation of siderophore biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000097", "l": "sulfur amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060440", "l": "trachea formation", "d": ["The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007433", "l": "larval salivary gland boundary specification", "d": ["Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1903319", "l": "positive regulation of protein maturation", "d": ["Any process that activates or increases the frequency, rate or extent of protein maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0050884", "l": "neuromuscular process controlling posture", "d": ["Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900293", "l": "positive regulation of galactotriose transport", "d": ["Any process that activates or increases the frequency, rate or extent of galactotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0001961", "l": "positive regulation of cytokine-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.640334783545086", "identifiers": [{"i": "GO:0002027", "l": "regulation of heart rate", "d": ["Any process that modulates the frequency or rate of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0043038", "l": "amino acid activation", "d": ["The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061320", "l": "pericardial nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015868", "l": "purine ribonucleotide transport", "d": ["The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031022", "l": "nuclear migration along microfilament", "d": ["The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007172", "l": "signal complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0003156", "l": "regulation of animal organ formation", "d": ["Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019512", "l": "lactose catabolic process via tagatose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.604533386108319", "identifiers": [{"i": "GO:0009058", "l": "biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032614", "l": "interleukin-11 production", "d": ["The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048661", "l": "positive regulation of smooth muscle cell proliferation", "d": ["Any process that activates or increases the rate or extent of smooth muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006710", "l": "androgen catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048077", "l": "negative regulation of compound eye pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904239", "l": "regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002412", "l": "antigen transcytosis by M cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010197", "l": "polar nucleus fusion", "d": ["The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045128", "l": "negative regulation of reciprocal meiotic recombination", "d": ["Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904268", "l": "positive regulation of Schwann cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060131", "l": "corticotropin hormone secreting cell development", "d": ["The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019522", "l": "ketogluconate metabolic process", "d": ["The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018232", "l": "peptide cross-linking via S-(L-isoglutamyl)-L-cysteine", "d": ["The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0043385", "l": "mycotoxin metabolic process", "d": ["The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904086", "l": "regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032759", "l": "positive regulation of TRAIL production", "d": ["Any process that activates or increases the frequency, rate, or extent of TRAIL production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900286", "l": "negative regulation of cellotriose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903772", "l": "regulation of viral budding via host ESCRT complex", "d": ["Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903297", "l": "regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.21615411226859", "identifiers": [{"i": "GO:0015849", "l": "organic acid transport", "d": ["The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051776", "l": "detection of redox state", "d": ["The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900303", "l": "regulation of laminaritriose transport", "d": ["Any process that modulates the frequency, rate or extent of laminaritriose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900930", "l": "negative regulation of L-tyrosine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035289", "l": "posterior head segmentation", "d": ["Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045149", "l": "acetoin metabolic process", "d": ["The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903315", "l": "negative regulation of nitrogen cycle metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904655", "l": "positive regulation of lung alveolus development", "d": ["Any process that activates or increases the frequency, rate or extent of lung alveolus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071670", "l": "smooth muscle cell chemotaxis", "d": ["The directed movement of a smooth muscle cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902462", "l": "positive regulation of mesenchymal stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072309", "l": "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis", "d": ["The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033525", "l": "sinapate ester biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042841", "l": "D-glucuronate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060455", "l": "negative regulation of gastric acid secretion", "d": ["Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150020", "l": "basal dendrite arborization", "d": ["The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150037", "l": "regulation of calcium-dependent activation of synaptic vesicle fusion", "d": ["Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006991", "l": "response to sterol depletion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905688", "l": "negative regulation of diacylglycerol kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033348", "l": "tetrose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036333", "l": "hepatocyte homeostasis", "d": ["Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003391", "l": "amphid sensory organ dendrite retrograde extension", "d": ["The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032663", "l": "regulation of interleukin-2 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-2 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072040", "l": "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis", "d": ["Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904290", "l": "negative regulation of mitotic DNA damage checkpoint", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018155", "l": "peptide cross-linking via sn-(2S,6R)-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006177", "l": "GMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006963", "l": "positive regulation of antibacterial peptide biosynthetic process", "d": ["Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035811", "l": "negative regulation of urine volume", "d": ["Any process that decreases the amount of urine excreted from the body over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0089703", "l": "L-aspartate transmembrane export from vacuole", "d": ["The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900159", "l": "positive regulation of bone mineralization involved in bone maturation", "d": ["Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032733", "l": "positive regulation of interleukin-10 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-10 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007504", "l": "larval fat body development", "d": ["The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006478", "l": "peptidyl-tyrosine sulfation", "d": ["The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0110116", "l": "regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901672", "l": "positive regulation of systemic acquired resistance", "d": ["Any process that activates or increases the frequency, rate or extent of systemic acquired resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035542", "l": "regulation of SNARE complex assembly", "d": ["Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.33683708723639", "identifiers": [{"i": "GO:0016042", "l": "lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061144", "l": "alveolar secondary septum development", "d": ["The progression of a secondary alveolar septum over time, from its formation to the mature structure. 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The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001555", "l": "oocyte growth", "d": ["The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036497", "l": "eIF2alpha dephosphorylation in response to endoplasmic reticulum stress", "d": ["The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015917", "l": "aminophospholipid transport", "d": ["The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003072", "l": "renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "d": ["The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110128", "l": "phloem sucrose unloading", "d": ["The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071924", "l": "chemokine (C-C motif) ligand 22 production", "d": ["The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902395", "l": "regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity", "d": ["Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000919", "l": "cell plate assembly", "d": ["The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0042661", "l": "regulation of mesodermal cell fate specification", "d": ["Any process that modulates the frequency, rate or extent of mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018940", "l": "orcinol metabolic process", "d": ["The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061471", "l": "karyomere assembly", "d": ["The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071369", "l": "cellular response to ethylene stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032363", "l": "FMN catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090091", "l": "positive regulation of extracellular matrix disassembly", "d": ["Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045103", "l": "intermediate filament-based process", "d": ["Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0060840", "l": "artery development", "d": ["The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030574", "l": "collagen catabolic process", "d": ["The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043251", "l": "sodium-dependent organic anion transport", "d": ["The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000064", "l": "regulation of cortisol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cortisol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0048641", "l": "regulation of skeletal muscle tissue development", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007430", "l": "terminal branching, open tracheal system", "d": ["Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032242", "l": "regulation of nucleoside transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070079", "l": "histone H4-R3 demethylation", "d": ["The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902488", "l": "cholangiocyte apoptotic process", "d": ["Any apoptotic process in a cholangiocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0006656", "l": "phosphatidylcholine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035335", "l": "peptidyl-tyrosine dephosphorylation", "d": ["The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048293", "l": "regulation of isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009955", "l": "adaxial/abaxial pattern specification", "d": ["The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006283", "l": "transcription-coupled nucleotide-excision repair", "d": ["The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0110096", "l": "cellular response to aldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019668", "l": "anaerobic catabolism of pairs of amino acids", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900898", "l": "positive regulation of heptadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051573", "l": "negative regulation of histone H3-K9 methylation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0006691", "l": "leukotriene metabolic process", "d": ["The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902235", "l": "regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904539", "l": "negative regulation of glycolytic process through fructose-6-phosphate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900234", "l": "regulation of Kit signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of Kit signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048094", "l": "male pigmentation", "d": ["Establishment of a pattern of pigment in males."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044477", "l": "envenomation resulting in negative regulation of platelet aggregation in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033604", "l": "negative regulation of catecholamine secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061298", "l": "retina vasculature development in camera-type eye", "d": ["The process whose specific outcome is the progression of the 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initiation", "d": ["Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042305", "l": "specification of segmental identity, mandibular segment", "d": ["The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060960", "l": "cardiac neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009788", "l": "negative regulation of abscisic acid-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007516", "l": "hemocyte development", "d": ["The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901007", "l": "(S)-scoulerine metabolic process", "d": ["The chemical reactions and pathways involving (S)-scoulerine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042128", "l": "nitrate assimilation", "d": ["The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032227", "l": "negative regulation of synaptic transmission, dopaminergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000511", "l": "regulation of granzyme A production", "d": ["Any process that modulates the frequency, rate or extent of granzyme A production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033548", "l": "myo-inositol hexakisphosphate biosynthetic process, lipid-independent", "d": ["The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900324", "l": "regulation of maltotriulose transport", "d": ["Any process that modulates the frequency, rate or extent of maltotriulose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1903350", "l": "response to dopamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097480", "l": "establishment of synaptic vesicle localization", "d": ["The directed movement of a synaptic vesicle or vesicles to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062109", "l": "regulation of DNA recombinase disassembly", "d": ["Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002393", "l": "lysosomal enzyme production involved in inflammatory response", "d": ["The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1901160", "l": "primary amino compound metabolic process", "d": ["The chemical reactions and pathways involving primary amino compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001173", "l": "DNA-templated transcriptional start site selection", "d": ["Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002349", "l": "histamine production involved in inflammatory response", "d": ["The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903870", "l": "positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0018992", "l": "germ-line sex determination", "d": ["The determination of sex and sexual phenotype in an organism's germ line."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010119", "l": "regulation of stomatal movement", "d": ["Any process that modulates the frequency, rate or extent of stomatal movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0016126", "l": "sterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905959", "l": "positive regulation of cellular response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042885", "l": "microcin B17 transport", "d": ["The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060672", "l": "epithelial cell morphogenesis involved in placental branching", "d": ["The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007305", "l": "vitelline membrane formation involved in chorion-containing eggshell formation", "d": ["Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0075260", "l": "regulation of spore-bearing organ development", "d": ["Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900842", "l": "positive regulation of helvolic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0022601", "l": "menstrual cycle phase", "d": ["The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019051", "l": "induction by virus of host apoptotic process", "d": ["Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902185", "l": "positive regulation of shoot apical meristem development", "d": ["Any process that activates or increases the frequency, rate or extent of shoot apical meristem development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903280", "l": "negative regulation of calcium:sodium antiporter activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042415", "l": "norepinephrine metabolic process", "d": ["The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904864", "l": "negative regulation of beta-catenin-TCF complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1905939", "l": "regulation of gonad development", "d": ["Any process that modulates the frequency, rate or extent of gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006025", "l": "galactosaminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010096", "l": "specification of sepal identity", "d": ["The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905385", "l": "negative regulation of protein localization to presynapse", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0021814", "l": "cell motility involved in cerebral cortex radial glia guided migration", "d": ["The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061754", "l": "negative regulation of circulating fibrinogen levels", "d": ["Any process that reduces the quantity of fibrinogen circulating in the bloodstream."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140469", "l": "GCN2-mediated signaling", "d": ["A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036516", "l": "chemoattraction of dopaminergic neuron axon", "d": ["The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0055090", "l": "acylglycerol homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045054", "l": "constitutive secretory pathway", "d": ["A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0001101", "l": "response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905485", "l": "positive regulation of motor neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of motor neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0061552", "l": "ganglion morphogenesis", "d": ["The process in which the anatomical structures of ganglion are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019399", "l": "cyclohexanol oxidation", "d": ["The cyclohexanol metabolic process in which cyclohexanol is converted to adipate."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046836", "l": "glycolipid transport", "d": ["The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901731", "l": "positive regulation of platelet aggregation", "d": ["Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903867", "l": "extraembryonic membrane development", "d": ["The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072287", "l": "metanephric distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a metanephric distal tubule are generated and organized. 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These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021565", "l": "accessory nerve development", "d": ["The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.204937007788899", "identifiers": [{"i": "GO:0006837", "l": "serotonin transport", "d": ["The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033350", "l": "apiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904744", "l": "positive regulation of telomeric DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061590", "l": "calcium activated phosphatidylcholine scrambling", "d": ["The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0097106", "l": "postsynaptic density organization", "d": ["A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0062033", "l": "positive regulation of mitotic sister chromatid segregation", "d": ["Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002565", "l": "somatic diversification of immune receptors via gene conversion", "d": ["The process in which immune receptor genes are diversified through gene conversion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060819", "l": "inactivation of X chromosome by genomic imprinting", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genomic imprinting."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061868", "l": "hepatic stellate cell migration", "d": ["The orderly movement of a hepatic stellate cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090717", "l": "adaptive immune memory response involving T cells and B cells", "d": ["An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0042762", "l": "regulation of sulfur metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010650", "l": "positive regulation of cell communication by electrical coupling", "d": ["Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900792", "l": "shamixanthone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shamixanthone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905326", "l": "positive regulation of meiosis I spindle assembly checkpoint", "d": ["Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901186", "l": "positive regulation of ERBB signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903141", "l": "negative regulation of establishment of endothelial barrier", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033307", "l": "phytol salvage", "d": ["A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061029", "l": "eyelid development in camera-type eye", "d": ["The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140717", "l": "entry into host through the stromata", "d": ["Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903815", "l": "negative regulation of collecting lymphatic vessel constriction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902265", "l": "abscisic acid homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903250", "l": "positive regulation of citrulline biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044392", "l": "peptidyl-lysine malonylation", "d": ["The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006768", "l": "biotin metabolic process", "d": ["The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904702", "l": "regulation of protein localization to adherens junction", "d": ["Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018081", "l": "peptide cross-linking via lanthionine or 3-methyl-lanthionine", "d": ["The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901792", "l": "3-(2,3-dihydroxyphenyl)propanoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042202", "l": "N-cyclopropylmelamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018189", "l": "pyrroloquinoline quinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060190", "l": "negative regulation of protein desumoylation", "d": ["Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021551", "l": "central nervous system morphogenesis", "d": ["The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904750", "l": "negative regulation of protein localization to nucleolus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900868", "l": "sarcinapterin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sarcinapterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002906", "l": "negative regulation of mature B cell apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019389", "l": "glucuronoside metabolic process", "d": ["The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903886", "l": "positive regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902730", "l": "positive regulation of proteoglycan biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990834", "l": "response to odorant", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0001932", "l": "regulation of protein phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0010389", "l": "regulation of G2/M transition of mitotic cell cycle", "d": ["Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010305", "l": "leaf vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the leaf of vascular plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003337", "l": "mesenchymal to epithelial transition involved in metanephros morphogenesis", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046060", "l": "dATP metabolic process", "d": ["The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.587491604362903", "identifiers": [{"i": "GO:0009101", "l": "glycoprotein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905148", "l": "negative regulation of smooth muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0007528", "l": "neuromuscular junction development", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032457", "l": "fast endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039698", "l": "polyadenylation of viral mRNA by polymerase stuttering", "d": ["Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902528", "l": "regulation of protein linear polyubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein linear polyubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015863", "l": "xanthosine transport", "d": ["The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099576", "l": "regulation of protein catabolic process at postsynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903430", "l": "negative regulation of cell maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018011", "l": "N-terminal peptidyl-alanine methylation", "d": ["The methylation of the N-terminal alanine of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0072017", "l": "distal tubule development", "d": ["The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032708", "l": "negative regulation of interleukin-24 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000730", "l": "DNA recombinase assembly", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060585", "l": "positive regulation of prostaglandin-endoperoxide synthase activity", "d": ["Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007380", "l": "specification of segmental identity, head", "d": ["The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1902175", "l": "regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904275", "l": "tricellular tight junction disassembly", "d": ["The disaggregation of a tricellular tight junction into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009696", "l": "salicylic acid metabolic process", "d": ["The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061962", "l": "negative regulation of heme oxygenase activity", "d": ["Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010057", "l": "trichoblast fate specification", "d": ["The process involved in the specification of a trichoblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0045777", "l": "positive regulation of blood pressure", "d": ["Any process in which the force of blood traveling through the circulatory system is increased."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052053", "l": "negative regulation by symbiont of host catalytic activity", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:1990542", "l": "mitochondrial transmembrane transport", "d": ["The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006241", "l": "CTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901232", "l": "regulation of convergent extension involved in axis elongation", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062030", "l": "negative regulation of stress granule assembly", "d": ["Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061790", "l": "dense core granule docking", "d": ["The initial attachment of a dense core granule membrane to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901498", "l": "response to tetralin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061482", "l": "response to irinotecan", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032926", "l": "negative regulation of activin receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902426", "l": "deactivation of mitotic spindle assembly checkpoint", "d": ["A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902225", "l": "negative regulation of acrosome reaction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046628", "l": "positive regulation of insulin receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of insulin receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904977", "l": "lymphatic endothelial cell migration", "d": ["The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990690", "l": "Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043535", "l": "regulation of blood vessel endothelial cell migration", "d": ["Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070534", "l": "protein K63-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0017009", "l": "protein-phycocyanobilin linkage", "d": ["The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039683", "l": "rolling circle double-stranded viral DNA replication", "d": ["A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902459", "l": "positive regulation of stem cell population maintenance", "d": ["Any process that activates or increases the frequency, rate or extent of stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048818", "l": "positive regulation of hair follicle maturation", "d": ["Any process that activates or increases the frequency, rate or extent of hair follicle maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036358", "l": "lipoteichoic acid D-alanylation", "d": ["The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0043981", "l": "histone H4-K5 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035719", "l": "tRNA import into nucleus", "d": ["The directed movement of tRNA from the cytoplasm to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0006874", "l": "intracellular calcium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045104", "l": "intermediate filament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046354", "l": "mannan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1902686", "l": "mitochondrial outer membrane permeabilization involved in programmed cell death", "d": ["The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030302", "l": "deoxynucleotide transport", "d": ["The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042754", "l": "negative regulation of circadian rhythm", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior."]}]} {"type": 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of preblastoderm mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003204", "l": "cardiac skeleton development", "d": ["The progression of the cardiac skeleton over time, from its formation to the mature structure. 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Results in release of the virus contents into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001046", "l": "positive regulation of integrin-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051466", "l": "positive regulation of corticotropin-releasing hormone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042540", "l": "hemoglobin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904245", "l": "regulation of polynucleotide adenylyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071140", "l": "resolution of mitotic recombination intermediates", "d": ["The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010399", "l": "rhamnogalacturonan I backbone metabolic process", "d": ["The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904552", "l": "regulation of chemotaxis to arachidonic acid", "d": ["Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032212", "l": "positive regulation of telomere maintenance via telomerase", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061781", "l": "mitotic cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042049", "l": "intracellular acyl-CoA homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of acyl-CoA within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036471", "l": "cellular response to glyoxal", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008065", "l": "establishment of blood-nerve barrier", "d": ["The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990417", "l": "snoRNA release from pre-rRNA", "d": ["The release of snoRNA from pre-rRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033121", "l": "regulation of purine nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002087", "l": "regulation of respiratory gaseous exchange by nervous system process", "d": ["A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. 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"identifiers": [{"i": "GO:1904550", "l": "response to arachidonic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035644", "l": "phosphoanandamide dephosphorylation", "d": ["The process of removing one or more phosphate groups from a phosphorylated anandamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071361", "l": "cellular response to ethanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.659114980698789", "identifiers": [{"i": "GO:0097205", "l": "renal filtration", "d": ["A renal system process in which 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metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006747", "l": "FAD biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006070", "l": "octanol metabolic process", "d": ["The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018356", "l": "protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine", "d": ["The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904256", "l": "positive regulation of iron ion transmembrane transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097070", "l": "ductus arteriosus closure", "d": ["The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0034198", "l": "cellular response to amino acid starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902526", "l": "negative regulation of protein monoubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009716", "l": "flavonoid phytoalexin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043640", "l": "benzoate catabolic process via hydroxylation", "d": ["The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0006089", "l": "lactate metabolic process", "d": ["The chemical reactions and pathways involving lactate, the anion of lactic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032278", "l": "positive regulation of gonadotropin secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070278", "l": "extracellular matrix constituent secretion", "d": ["The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099185", "l": "postsynaptic intermediate filament cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.491863471761647", "identifiers": [{"i": "GO:0031668", "l": "cellular response to extracellular stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034173", "l": "positive regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006052", "l": "N-acetylmannosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010020", "l": "chloroplast fission", "d": ["The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905535", "l": "regulation of eukaryotic translation initiation factor 4F complex assembly", "d": ["Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903041", "l": "regulation of chondrocyte hypertrophy", "d": ["Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0090278", "l": "negative regulation of peptide hormone secretion", "d": ["Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901601", "l": "strigolactone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of strigolactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000436", "l": "carbon catabolite activation of transcription from RNA polymerase II promoter", "d": ["Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048346", "l": "positive regulation of paraxial mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0036135", "l": "Schwann cell migration", "d": ["The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902780", "l": "response to nonane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006232", "l": "TDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.312708028507217", "identifiers": [{"i": "GO:0051493", "l": "regulation of cytoskeleton organization", "d": ["Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051553", "l": "flavone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014836", "l": "myoblast fate commitment involved in skeletal muscle regeneration", "d": ["The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019586", "l": "galacturonate metabolic process", "d": ["The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0099623", "l": "regulation of cardiac muscle cell membrane repolarization", "d": ["Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090208", "l": "positive regulation of triglyceride metabolic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060625", "l": "regulation of protein deneddylation", "d": ["Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018260", "l": "protein guanylylation", "d": ["The addition of phospho-guanosine to a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001174", "l": "transcriptional start site selection at RNA polymerase II promoter", "d": ["Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000483", "l": "endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0072237", "l": "metanephric proximal tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048775", "l": "regulation of leucophore differentiation", "d": ["Any process that modulates the frequency, rate or extent of leucophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0050926", "l": "regulation of positive chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032043", "l": "mitochondrial DNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043330", "l": "response to exogenous dsRNA", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901414", "l": "negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900518", "l": "regulation of response to pullulan", "d": ["Any process that modulates the frequency, rate or extent of response to pullulan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019547", "l": "arginine catabolic process to ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045852", "l": "pH elevation", "d": ["Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902384", "l": "glycyrrhetinate metabolic process", "d": ["The chemical reactions and pathways involving glycyrrhetinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048402", "l": "intermediate mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070886", "l": "positive regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071285", "l": "cellular response to lithium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048674", "l": "collateral sprouting of injured axon", "d": ["The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903801", "l": "L-leucine import across plasma membrane", "d": ["The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018914", "l": "chlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034393", "l": "positive regulation of smooth muscle cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0008358", "l": "maternal determination of anterior/posterior axis, embryo", "d": ["The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:1903725", "l": "regulation of phospholipid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phospholipid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0043112", "l": "receptor metabolic process", "d": ["The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900608", "l": "tensidol B biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tensidol B."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.33219452504607", "identifiers": [{"i": "GO:0019953", "l": "sexual reproduction", "d": ["A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043213", "l": "bacteriocin transport", "d": ["The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.710521892834109", "identifiers": [{"i": "GO:0032412", "l": "regulation of monoatomic ion transmembrane transporter activity", "d": ["Any process that modulates the activity of an ion transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010139", "l": "pyrimidine deoxyribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044348", "l": "plant-type cell wall cellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0002228", "l": "natural killer cell mediated immunity", "d": ["The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901229", "l": "regulation of non-canonical Wnt signaling pathway via JNK cascade", "d": ["Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0022038", "l": "corpus callosum development", "d": ["The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032124", "l": "macronucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0000305", "l": "response to oxygen radical", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002493", "l": "lipid antigen assembly with MHC class Ib protein complex", "d": ["The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0044242", "l": "cellular lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099043", "l": "cargo loading involved in clathrin-dependent endocytosis", "d": ["Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000309", "l": "positive regulation of tumor necrosis factor (ligand) superfamily member 11 production", "d": ["Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903935", "l": "response to sodium arsenite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0072077", "l": "renal vesicle morphogenesis", "d": ["The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032773", "l": "positive regulation of tyrosinase activity", "d": ["Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900812", "l": "helvolic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of helvolic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010823", "l": "negative regulation of mitochondrion organization", "d": ["Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080188", "l": "gene silencing by RNA-directed DNA methylation", "d": ["A small RNA-based gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106213", "l": "kinetochore disassembly involved in meiotic chromosome organization", "d": ["The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900244", "l": "positive regulation of synaptic vesicle endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0002759", "l": "regulation of antimicrobial humoral response", "d": ["Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903344", "l": "regulation of protein polyglycylation", "d": ["Any process that modulates the frequency, rate or extent of protein polyglycylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904005", "l": "regulation of phospholipase D activity", "d": ["Any process that modulates the frequency, rate or extent of phospholipase D activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033541", "l": "fatty acid beta-oxidation, unsaturated, odd number", "d": ["A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021691", "l": "cerebellar Purkinje cell layer maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032014", "l": "positive regulation of ARF protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048810", "l": "female analia morphogenesis", "d": ["The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010547", "l": "thylakoid membrane disassembly", "d": ["The controlled breakdown of the thylakoid membrane in the context of a normal process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0071632", "l": "optomotor response", "d": ["Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021893", "l": "cerebral cortex GABAergic interneuron fate commitment", "d": ["The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0051170", "l": "import into nucleus", "d": ["The directed movement of substances into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900968", "l": "regulation of sarcinapterin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099551", "l": "trans-synaptic signaling by neuropeptide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042861", "l": "achromobactin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0030323", "l": "respiratory tube development", "d": ["The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160058", "l": "plant endodermal cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a plant endodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0007308", "l": "oocyte construction", "d": ["The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0099011", "l": "neuronal dense core vesicle exocytosis", "d": ["The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045654", "l": "positive regulation of megakaryocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098939", "l": "dendritic transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in nerve cell dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002012", "l": "vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure", "d": ["A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090158", "l": "endoplasmic reticulum membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075195", "l": "negative regulation of haustorium mother cell formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.534962635636688", "identifiers": [{"i": "GO:0006325", "l": "chromatin organization", "d": ["The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140403", "l": "effector-mediated suppression of host innate immune response", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046049", "l": "UMP metabolic process", "d": ["The chemical reactions and pathways involving UMP, uridine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019244", "l": "lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate."]}, {"i": "REACT:R-HSA-71849.1", "d": []}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150011", "l": "regulation of neuron projection arborization", "d": ["Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001193", "l": "maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II", "d": ["Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0002887", "l": "negative regulation of myeloid leukocyte mediated immunity", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900437", "l": "regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus", "d": ["Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032572", "l": "response to menaquinone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016339", "l": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900885", "l": "negative regulation of tridecane biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905315", "l": "cell proliferation involved in endocardial cushion morphogenesis", "d": ["Any cell proliferation that is involved in endocardial cushion morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901815", "l": "astaxanthin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of astaxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015720", "l": "allantoin transport", "d": ["The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003222", "l": "ventricular trabecula myocardium morphogenesis", "d": ["The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0010016", "l": "shoot system morphogenesis", "d": ["The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1903059", "l": "regulation of protein lipidation", "d": ["Any process that modulates the frequency, rate or extent of protein lipidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140982", "l": "detoxification of aluminum ion", "d": ["Any process that reduce or remove the toxicity of aluminum ions. These can include transport of the aluminum away from sensitive areas, sequesteration, or chemical modification to an inert form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140331", "l": "aminophospholipid translocation", "d": ["The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0052779", "l": "amino disaccharide metabolic process", "d": ["The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.987180592322588", "identifiers": [{"i": "GO:0016050", "l": "vesicle organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031542", "l": "positive regulation of anthocyanin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0006937", "l": "regulation of muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009558", "l": "embryo sac cellularization", "d": ["The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901103", "l": "gramicidin S biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gramicidin S."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0015803", "l": "branched-chain amino acid transport", "d": ["The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046366", "l": "allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002489", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032402", "l": "melanosome transport", "d": ["The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061729", "l": "GDP-mannose biosynthetic process from fructose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate."]}, {"i": "REACT:R-HSA-446205", "l": "Synthesis of GDP-mannose (Homo sapiens)", "d": []}]} {"type": "biolink:BiologicalProcess", "ic": "56.121789804970717", "identifiers": [{"i": "GO:0034654", "l": "nucleobase-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070292", "l": "N-acylphosphatidylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903365", "l": "regulation of fear response", "d": ["Any process that modulates the frequency, rate or extent of fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002581", "l": "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1990772", "l": "substance P secretion", "d": ["The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042402", "l": "cellular biogenic amine catabolic process", "d": ["The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900969", "l": "negative regulation of sarcinapterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904523", "l": "regulation of DNA amplification", "d": ["Any process that modulates the frequency, rate or extent of DNA amplification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903446", "l": "geraniol metabolic process", "d": ["The chemical reactions and pathways involving geraniol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000317", "l": "negative regulation of T-helper 17 type immune response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070543", "l": "response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902978", "l": "premeiotic DNA replication termination", "d": ["Any DNA replication termination involved in meiotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048262", "l": "determination of dorsal/ventral asymmetry", "d": ["Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140207", "l": "tripeptide import across plasma membrane", "d": ["The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060682", "l": "primary ureteric bud growth", "d": ["The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015869", "l": "protein-DNA complex transport", "d": ["The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905908", "l": "positive regulation of amyloid fibril formation", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid fibril formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990638", "l": "response to granulocyte colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000524", "l": "negative regulation of T cell costimulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034213", "l": "quinolinate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039671", "l": "evasion by virus of host natural killer cell activity", "d": ["Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903700", "l": "caecum development", "d": ["The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106028", "l": "neuron projection retraction", "d": ["The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.6720795298599", "identifiers": [{"i": "GO:0006109", "l": "regulation of carbohydrate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034760", "l": "negative regulation of iron ion transmembrane transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904853", "l": "protein localization to ascospore wall", "d": ["A process in which a protein is transported to, or maintained in, a location within an ascospore wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010084", "l": "specification of animal organ axis polarity", "d": ["The process in which the polarity of an animal organ axis is specified."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000954", "l": "regulation of cyclodextrin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0060918", "l": "auxin transport", "d": ["The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034631", "l": "microtubule anchoring at spindle pole body", "d": ["Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072714", "l": "response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905486", "l": "regulation of anterior/posterior axon guidance", "d": ["Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030418", "l": "nicotianamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042339", "l": "keratan sulfate metabolic process", "d": ["The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060519", "l": "cell adhesion involved in prostatic bud elongation", "d": ["The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071249", "l": "cellular response to nitrate", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904683", "l": "regulation of metalloendopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of metalloendopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0019941", "l": "modification-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904907", "l": "regulation of maintenance of mitotic sister chromatid cohesion, telomeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051294", "l": "establishment of spindle orientation", "d": ["Any process that set the alignment of spindle relative to other cellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106062", "l": "positive regulation of exit from meiosis", "d": ["Any process that activates or increases the frequency, rate or extent of exit from meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904879", "l": "positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "33.650106285053191", "identifiers": [{"i": "GO:0065007", "l": "biological regulation", "d": ["Any process that modulates a measurable attribute of any biological process, quality or function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090319", "l": "positive regulation of chylomicron remodeling", "d": ["Any process that increases the rate, frequency, or extent of chylomicron remodeling. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:0040017", "l": "positive regulation of locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010439", "l": "regulation of glucosinolate biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060646", "l": "internal mammary gland bud epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042201", "l": "N-cyclopropylmelamine metabolic process", "d": ["The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019364", "l": "pyridine nucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060558", "l": "regulation of calcidiol 1-monooxygenase activity", "d": ["Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001276", "l": "regulation of leucine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of leucine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.607857429186669", "identifiers": [{"i": "GO:1901576", "l": "organic substance biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090367", "l": "negative regulation of mRNA modification", "d": ["Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002801", "l": "negative regulation of antifungal peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042776", "l": "proton motive force-driven mitochondrial ATP synthesis", "d": ["The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0038016", "l": "insulin receptor internalization", "d": ["A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0051055", "l": "negative regulation of lipid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034630", "l": "RITS complex localization", "d": ["Any process in which a RITS complex is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014734", "l": "skeletal muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006108", "l": "malate metabolic process", "d": ["The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902690", "l": "positive regulation of NAD metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of NAD metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046435", "l": "3-(3-hydroxy)phenylpropionate metabolic process", "d": ["The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071681", "l": "cellular response to indole-3-methanol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051066", "l": "dihydrobiopterin metabolic process", "d": ["The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902530", "l": "positive regulation of protein linear polyubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904798", "l": "positive regulation of core promoter binding", "d": ["Any process that activates or increases the frequency, rate or extent of core promoter binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009083", "l": "branched-chain amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904794", "l": "negative regulation of euchromatin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901482", "l": "L-lysine import into vacuole involved in cellular response to nitrogen starvation", "d": ["A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901398", "l": "regulation of transforming growth factor beta3 activation", "d": ["Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033346", "l": "asparagine catabolic process via 2-oxosuccinamate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903012", "l": "positive regulation of bone development", "d": ["Any process that activates or increases the frequency, rate or extent of bone development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097287", "l": "7-cyano-7-deazaguanine metabolic process", "d": ["The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120150", "l": "regulation of mitotic actomyosin contractile ring disassembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046457", "l": "prostanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902601", "l": "silver ion transmembrane transport", "d": ["The directed movement of silver ion across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072581", "l": "protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine", "d": ["The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900419", "l": "regulation of cellular alcohol catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0034643", "l": "establishment of mitochondrion localization, microtubule-mediated", "d": ["The directed movement of the mitochondrion to a specific location, by a process involving microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990120", "l": "messenger ribonucleoprotein complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903385", "l": "regulation of homophilic cell adhesion", "d": ["Any process that modulates the frequency, rate or extent of homophilic cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900470", "l": "positive regulation of phosphatidylserine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042376", "l": "phylloquinone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042135", "l": "neurotransmitter catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061549", "l": "sympathetic ganglion development", "d": ["The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070348", "l": "negative regulation of brown fat cell proliferation", "d": ["Any process that stops or decreases the rate or extent of brown fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046804", "l": "peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide", "d": ["The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905048", "l": "regulation of metallopeptidase activity", "d": ["Any process that modulates the frequency, rate or extent of metallopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0005989", "l": "lactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902840", "l": "positive regulation of nuclear migration along microtubule", "d": ["Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120248", "l": "acetylenic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.022889380119096", "identifiers": [{"i": "GO:0008016", "l": "regulation of heart contraction", "d": ["Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900192", "l": "positive regulation of single-species biofilm formation", "d": ["Any process that activates or increases the frequency, rate or extent of single-species biofilm formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006004", "l": "fucose metabolic process", "d": ["The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007298", "l": "border follicle cell migration", "d": ["The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039653", "l": "suppression by virus of host transcription", "d": ["Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2001100", "l": "pentasaccharide transport", "d": ["The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0080111", "l": "DNA demethylation", "d": ["The removal of a methyl group from one or more nucleotides within an DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.519625387257847", "identifiers": [{"i": "GO:0071554", "l": "cell wall organization or biogenesis", "d": ["A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903613", "l": "regulation of protein tyrosine phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0034381", "l": "plasma lipoprotein particle clearance", "d": ["The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001661", "l": "conditioned taste aversion", "d": ["A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900342", "l": "regulation of methane biosynthetic process from dimethyl sulfide", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072265", "l": "metanephric capsule morphogenesis", "d": ["The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900582", "l": "o-orsellinic acid metabolic process", "d": ["The chemical reactions and pathways involving o-orsellinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.381699370032315", "identifiers": [{"i": "GO:0010646", "l": "regulation of cell communication", "d": ["Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0000091", "l": "mitotic anaphase A", "d": ["The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070508", "l": "cholesterol import", "d": ["The directed movement of cholesterol into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900241", "l": "positive regulation of phenotypic switching", "d": ["Any process that activates or increases the frequency, rate or extent of phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905518", "l": "regulation of presynaptic active zone assembly", "d": ["Any process that modulates the frequency, rate or extent of presynaptic active zone assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048163", "l": "scattered antral spaces stage", "d": ["The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061624", "l": "fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046371", "l": "dTDP-mannose metabolic process", "d": ["The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902081", "l": "negative regulation of calcium ion import into sarcoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014881", "l": "regulation of myofibril size", "d": ["Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060773", "l": "flower phyllotactic patterning", "d": ["The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901533", "l": "negative regulation of hematopoietic progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0072348", "l": "sulfur compound transport", "d": ["The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.113052157604244", "identifiers": [{"i": "GO:0009890", "l": "negative regulation of biosynthetic process", "d": ["Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901860", "l": "positive regulation of mitochondrial DNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042351", "l": "'de novo' GDP-L-fucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072004", "l": "kidney field specification", "d": ["The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036089", "l": "cleavage furrow formation", "d": ["Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000203", "l": "regulation of ribosomal large subunit export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052067", "l": "disruption of host phagocytosis", "d": ["A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021532", "l": "neural tube patterning", "d": ["The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072151", "l": "mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070584", "l": "mitochondrion morphogenesis", "d": ["The process in which the anatomical structures of a mitochondrion are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090610", "l": "bundle sheath cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0030493", "l": "bacteriochlorophyll metabolic process", "d": ["The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904260", "l": "negative regulation of basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.246254797494437", "identifiers": [{"i": "GO:0030334", "l": "regulation of cell migration", "d": ["Any process that modulates the frequency, rate or extent of cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902325", "l": "negative regulation of chlorophyll biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905351", "l": "pericyte cell migration", "d": ["The orderly movement of a pericyte cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904456", "l": "negative regulation of neuronal action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905377", "l": "response to D-galactose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070446", "l": "negative regulation of oligodendrocyte progenitor proliferation", "d": ["Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010061", "l": "regulation of trichoblast fate specification", "d": ["Any process that modulates trichoblast fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046288", "l": "isoflavonoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0044786", "l": "cell cycle DNA replication", "d": ["The DNA-dependent DNA replication that takes place as part of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009300", "l": "antisense RNA transcription", "d": ["The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903988", "l": "iron ion export across plasma membrane", "d": ["The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071613", "l": "granzyme B production", "d": ["The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006509", "l": "membrane protein ectodomain proteolysis", "d": ["The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052403", "l": "negative regulation by host of symbiont catalytic activity", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034161", "l": "positive regulation of toll-like receptor 8 signaling pathway", "d": ["Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0050957", "l": "equilibrioception", "d": ["The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033148", "l": "positive regulation of intracellular estrogen receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045496", "l": "male analia development", "d": ["The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099546", "l": "protein catabolic process, modulating synaptic transmission", "d": ["Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900883", "l": "17-methylnonadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070241", "l": "positive regulation of activated T cell autonomous cell death", "d": ["Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038014", "l": "negative regulation of insulin receptor signaling pathway by insulin receptor internalization", "d": ["Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.828717300131117", "identifiers": [{"i": "GO:0030879", "l": "mammary gland development", "d": ["The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000237", "l": "positive regulation of tRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044761", "l": "negative regulation by symbiont of host cholinergic synaptic transmission", "d": ["Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010448", "l": "vegetative meristem growth", "d": ["The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060034", "l": "notochord cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071217", "l": "cellular response to external biotic stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072268", "l": "pattern specification involved in metanephros development", "d": ["Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006042", "l": "glucosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901143", "l": "insulin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042479", "l": "positive regulation of eye photoreceptor cell development", "d": ["Any process that activates or increases the frequency, rate or extent of eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0042168", "l": "heme metabolic process", "d": ["The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097290", "l": "alpha-ribazole biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051079", "l": "meiosis I nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes during the first division of meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075521", "l": "microtubule-dependent intracellular transport of viral material towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0051647", "l": "nucleus localization", "d": ["Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042369", "l": "vitamin D catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000632", "l": "negative regulation of pre-miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003387", "l": "neuron differentiation involved in amphid sensory organ development", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010799", "l": "regulation of peptidyl-threonine phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098545", "l": "maintenance of protein complex location in cytoplasm", "d": ["Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904211", "l": "membrane protein proteolysis involved in retrograde protein transport, ER to cytosol", "d": ["Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046324", "l": "regulation of glucose import", "d": ["Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902043", "l": "positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "d": ["Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0009062", "l": "fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110101", "l": "L-valine transmembrane import into vacuole", "d": ["The directed movement of L-valine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120179", "l": "adherens junction disassembly", "d": ["The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904890", "l": "negative regulation of excitatory synapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060185", "l": "outer ear unfolding", "d": ["The opening and spreading out of the outer ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033223", "l": "2-aminoethylphosphonate transport", "d": ["The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009211", "l": "pyrimidine deoxyribonucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000878", "l": "positive regulation of oligopeptide transport", "d": ["Any process that activates or increases the frequency, rate or extent of oligopeptide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070574", "l": "cadmium ion transmembrane transport", "d": ["A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003432", "l": "cell growth involved in growth plate cartilage chondrocyte morphogenesis", "d": ["The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046296", "l": "glycolate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060952", "l": "cardiac glial cell development", "d": ["The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0098869", "l": "cellular oxidant detoxification", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055012", "l": "ventricular cardiac muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060567", "l": "negative regulation of termination of DNA-templated transcription", "d": ["Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905165", "l": "regulation of lysosomal protein catabolic process", "d": ["Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002337", "l": "B-1a B cell differentiation", "d": ["The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0040002", "l": "collagen and cuticulin-based cuticle development", "d": ["Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002309", "l": "T cell proliferation involved in immune response", "d": ["The expansion of a T cell population by cell division as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071423", "l": "malate transmembrane transport", "d": ["A process in which a malate ion is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048102", "l": "autophagic cell death", "d": ["A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019671", "l": "glutamate catabolic process via mesaconate and citramalate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901319", "l": "positive regulation of trehalose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of trehalose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0080164", "l": "regulation of nitric oxide metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904237", "l": "positive regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0072490", "l": "toluene-containing compound metabolic process", "d": ["The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045317", "l": "equator specification", "d": ["The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0034063", "l": "stress granule assembly", "d": ["The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044098", "l": "DNA secretion by the type IV secretion system", "d": ["The controlled release of DNA by a cell, via the type IV secretion system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061219", "l": "mesonephric mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901089", "l": "acetate ester metabolic process involved in fermentation", "d": ["Any acetate ester metabolic process that is involved in fermentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060345", "l": "spleen trabecula formation", "d": ["The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043061", "l": "meiotic metaphase II chromosome alignment", "d": ["A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiosis II chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098670", "l": "entry receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900398", "l": "negative regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072115", "l": "head kidney morphogenesis", "d": ["The process in which the anatomical structures of the head kidney are generated and organized. 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An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070223", "l": "sulfide oxidation, using sulfur dioxygenase", "d": ["A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002503", "l": "peptide antigen assembly with MHC class II protein complex", "d": ["The binding of a peptide to the antigen binding groove of an MHC class II protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043489", "l": "RNA stabilization", "d": ["Prevention of degradation of RNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.752564210074205", "identifiers": [{"i": "GO:0044003", "l": "modulation by symbiont of host process", "d": ["The process in which a symbiont organism effects a change in the structure or processes of 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014053", "l": "negative regulation of gamma-aminobutyric acid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.693390461713108", "identifiers": [{"i": "GO:0030030", "l": "cell projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035475", "l": "angioblast cell migration involved in selective angioblast sprouting", "d": ["The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001137", "l": "positive regulation of endocytic recycling", "d": ["Any process that activates or increases the frequency, rate or extent of endocytic recycling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072670", "l": "mitochondrial tRNA threonylcarbamoyladenosine modification", "d": ["The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031112", "l": "positive regulation of microtubule polymerization or depolymerization", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007225", "l": "patched ligand maturation", "d": ["The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019082", "l": "viral protein processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072105", "l": "ureteric peristalsis", "d": ["A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1905207", "l": "regulation of cardiocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0050919", "l": "negative chemotaxis", "d": ["The directed movement of a motile cell or organism towards a lower concentration of a chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.86427600823658", "identifiers": [{"i": "GO:0097435", "l": "supramolecular fiber organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000691", "l": "negative regulation of cardiac muscle cell myoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903499", "l": "regulation of mitotic actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048721", "l": "clypeus morphogenesis", "d": ["The process in which the anatomical structures of the clypeus are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0045144", "l": "meiotic sister chromatid segregation", "d": ["The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000318", "l": "positive regulation of T-helper 17 type immune response", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002491", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class II", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036372", "l": "opsin transport", "d": ["The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062196", "l": "regulation of lysosome size", "d": ["Any process that modulates the size of a lysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.236426385580998", "identifiers": [{"i": "GO:0060986", "l": "endocrine hormone secretion", "d": ["The regulated release of a hormone into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0061140", "l": "lung secretory cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. 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Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904820", "l": "peritoneum development", "d": ["The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097084", "l": "vascular associated smooth muscle cell development", "d": ["The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000381", "l": "negative regulation of mesoderm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990478", "l": "response to ultrasound", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060338", "l": "regulation of type I interferon-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0042816", "l": "vitamin B6 metabolic process", "d": ["The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090104", "l": "pancreatic epsilon cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. 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The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048146", "l": "positive regulation of fibroblast proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042839", "l": "D-glucuronate metabolic process", "d": ["The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061257", "l": "mesonephric podocyte development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. 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Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0008214", "l": "protein dealkylation", "d": ["The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021902", "l": "commitment of neuronal cell to specific neuron type in forebrain", "d": ["The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033545", "l": "myo-inositol hexakisphosphate biosynthetic process, lipid-dependent", "d": ["The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009175", "l": "pyrimidine ribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043154", "l": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010262", "l": "somatic embryogenesis", "d": ["Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140917", "l": "zinc ion import into mitochondrion", "d": ["The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019504", "l": "L-proline betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006227", "l": "dUDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903123", "l": "regulation of thioredoxin peroxidase activity", "d": ["Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0050898", "l": "nitrile metabolic process", "d": ["The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901124", "l": "bacitracin A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of bacitracin A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032875", "l": "regulation of DNA endoreduplication", "d": ["Any process that modulates the frequency, rate or extent of DNA endoreduplication."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0009410", "l": "response to xenobiotic stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. 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"92.728541327098611", "identifiers": [{"i": "GO:0070206", "l": "protein trimerization", "d": ["The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030153", "l": "bacteriocin immunity", "d": ["A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009563", "l": "synergid differentiation", "d": ["The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044855", "l": "plasma membrane raft distribution", "d": ["The process that establishes the spatial arrangement of membrane rafts within a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035185", "l": "preblastoderm mitotic cell cycle", "d": ["The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.216808612803263", "identifiers": [{"i": "GO:0001909", "l": "leukocyte mediated cytotoxicity", "d": ["The directed killing of a target cell by a leukocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018897", "l": "dibenzothiophene desulfurization", "d": ["The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099158", "l": "regulation of recycling endosome localization within postsynapse", "d": ["Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003105", "l": "negative regulation of glomerular filtration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. 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A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042331", "l": "phototaxis", "d": ["The directed movement of a motile cell or organism in response to light."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904749", "l": "regulation of protein localization to nucleolus", "d": ["Any process that modulates the frequency, rate or extent of protein localization to nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042966", "l": "biotin carboxyl carrier protein biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.429197379601746", "identifiers": [{"i": "GO:0050906", "l": "detection of stimulus involved in sensory perception", "d": ["The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905044", "l": "regulation of Schwann cell proliferation involved in axon regeneration", "d": ["Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036367", "l": "light adaption", "d": ["The ability of a photoreceptor to adjust to varying levels of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990108", "l": "protein linear deubiquitination", "d": ["A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009252", "l": "peptidoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000292", "l": "RNA fragment catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097385", "l": "programmed necrotic cell death in response to starvation", "d": ["A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097343", "l": "ripoptosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035901", "l": "cellular response to isolation stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061739", "l": "protein lipidation involved in autophagosome assembly", "d": ["The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.249364371823347", "identifiers": [{"i": "GO:0006397", "l": "mRNA processing", "d": ["Any process involved in 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reduces the frequency, rate or extent of nurse cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075290", "l": "regulation of aplanospore formation", "d": ["Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0046246", "l": "terpene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0008608", "l": "attachment of spindle microtubules to kinetochore", "d": ["The process in which spindle 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STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010352", "l": "lithium ion export across the plasma membrane", "d": ["The directed movement of lithium ion out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001058", "l": "D-tagatose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving a D-tagatose 6-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061692", "l": "cellular detoxification of hydrogen peroxide", "d": ["Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900129", "l": "positive regulation of G-protein activated inward rectifier potassium channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007384", "l": "specification of segmental identity, thorax", "d": ["The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1902624", "l": "positive regulation of neutrophil migration", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0141061", "l": "disruption of cell in another organism", "d": ["The disruption of a cell of another organism, leading to damage or temporary subversion of that cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070706", "l": "RNA nucleotide deletion", "d": ["The modification of an RNA molecule by removal of a single nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034176", "l": "negative regulation of toll-like receptor 12 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002717", "l": "positive regulation of natural killer cell mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002099", "l": "tRNA wobble guanine modification", "d": ["The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.17729949190246", "identifiers": [{"i": "GO:0043009", "l": "chordate embryonic development", "d": ["The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002593", "l": "negative regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901740", "l": "negative regulation of myoblast fusion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0015740", "l": "C4-dicarboxylate transport", "d": ["The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061196", "l": "fungiform papilla development", "d": ["The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905822", "l": "regulation of mitotic sister chromatid arm separation", "d": ["Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019240", "l": "citrulline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904707", "l": "positive regulation of vascular associated smooth muscle cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902907", "l": "proteasome storage granule disassembly", "d": ["The disaggregation of a proteasome storage granule into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110052", "l": "toxic metabolite repair", "d": ["A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051450", "l": "myoblast proliferation", "d": ["The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060845", "l": "venous endothelial cell fate commitment", "d": ["The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051949", "l": "negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021663", "l": "rhombomere 4 formation", "d": ["The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051335", "l": "meiosis II nuclear membrane reassembly", "d": ["The reformation of the nuclear membrane during meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0097709", "l": "connective tissue replacement", "d": ["The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905844", "l": "negative regulation of cellular response to gamma radiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903983", "l": "positive regulation of 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"identifiers": [{"i": "GO:0015962", "l": "diadenosine triphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036395", "l": "pancreatic amylase secretion", "d": ["The controlled release of amylase from a cell of the pancreas."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018877", "l": "beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:1900911", "l": "regulation of olefin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of olefin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000076", "l": "positive regulation of cytokinesis, site selection", "d": ["Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050831", "l": "male-specific defense response to bacterium", "d": ["A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904533", "l": "regulation of telomeric loop disassembly", "d": ["Any process that modulates the frequency, rate or extent of telomeric loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.855577547738939", "identifiers": [{"i": "GO:0051171", "l": "regulation of nitrogen compound metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0070230", "l": "positive regulation of lymphocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036527", "l": "peptidyl-arginine deglycation", "d": ["The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900826", "l": "negative regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.25778018697109", "identifiers": [{"i": "GO:1901616", "l": "organic hydroxy compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905909", "l": "regulation of dauer entry", "d": ["Any process that modulates the frequency, rate or extent of dauer entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062233", "l": "F2-isoprostane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F2-isoprostane."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0072171", "l": "mesonephric tubule morphogenesis", "d": ["The process in which the anatomical 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A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048571", "l": "long-day photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001188", "l": "regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell", "d": ["Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045904", "l": "negative regulation of translational termination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990066", "l": "energy quenching", "d": ["The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030718", "l": "germ-line stem cell population maintenance", "d": ["Any process by which an organism or tissue maintains a population of germ-line stem cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903749", "l": "positive regulation of establishment of protein localization to mitochondrion", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0055001", "l": "muscle cell development", "d": ["The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1990845", "l": "adaptive thermogenesis", "d": ["The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905633", "l": "establishment of protein localization to euchromatin", "d": ["The directed movement of a protein to a specific location in an euchromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032789", "l": "unsaturated monocarboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990255", "l": "subsynaptic reticulum organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048134", "l": "germ-line cyst formation", "d": ["Formation of a group of interconnected cells derived from a single gonial founder cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0120186", "l": "negative regulation of protein localization to chromatin", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071679", "l": "commissural neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046342", "l": "CDP-diacylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901633", "l": "negative regulation of synaptic vesicle membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.192536265397877", "identifiers": [{"i": "GO:0007605", "l": "sensory perception of sound", "d": ["The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901630", "l": "negative regulation of presynaptic membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010694", "l": "positive regulation of alkaline phosphatase activity", "d": ["Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903406", "l": "regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090063", "l": "positive regulation of microtubule nucleation", "d": ["Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901962", "l": "S-adenosyl-L-methionine transmembrane transport", "d": ["The directed movement of S-adenosyl-L-methionine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900607", "l": "tensidol B catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of tensidol B."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003203", "l": "endocardial cushion morphogenesis", "d": ["The process in which the anatomical structure of the endocardial cushion is generated and organized. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002195", "l": "2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis", "d": ["The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0042053", "l": "regulation of dopamine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0010972", "l": "negative regulation of G2/M transition of mitotic cell cycle", "d": ["Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097101", "l": "blood vessel endothelial cell fate specification", "d": ["The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0001539", "l": "cilium or flagellum-dependent cell motility", "d": ["Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060743", "l": "epithelial cell maturation involved in prostate gland development", "d": ["The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060085", "l": "smooth muscle relaxation of the bladder outlet", "d": ["A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002925", "l": "positive regulation of humoral immune response mediated by circulating immunoglobulin", "d": ["Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110027", "l": "negative regulation of DNA strand resection involved in replication fork processing", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001003", "l": "regulation of pectin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of pectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075316", "l": "negative regulation of basidium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030916", "l": "otic vesicle formation", "d": ["The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900799", "l": "cordyol C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cordyol C."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051968", "l": "positive regulation of synaptic transmission, glutamatergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0006641", "l": "triglyceride metabolic process", "d": ["The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903348", "l": "positive regulation of bicellular tight junction assembly", "d": ["Any process that activates or increases the frequency, rate or extent of tight junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0000378", "l": "RNA exon ligation", "d": ["The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0048086", "l": "negative regulation of developmental pigmentation", "d": ["Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001205", "l": "negative regulation of osteoclast development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901500", "l": "response to p-xylene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905842", "l": "cellular response to oxidopamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905782", "l": "positive regulation of phosphatidylserine exposure on apoptotic cell surface", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006982", "l": "response to lipid hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046171", "l": "octanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051387", "l": "negative regulation of neurotrophin TRK receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002202", "l": "somatic diversification of variable lymphocyte receptors of jawless fish", "d": ["The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901059", "l": "p-hydroxyphenyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034695", "l": "response to prostaglandin E", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.259351300077434", "identifiers": [{"i": "GO:0001667", "l": "ameboidal-type cell migration", "d": ["Cell migration that is accomplished by extension and retraction of a pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018269", "l": "GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902769", "l": "regulation of choline O-acetyltransferase activity", "d": ["Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075276", "l": "regulation of telium development", "d": ["Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:2000967", "l": "negative regulation of cell wall polysaccharide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0061215", "l": "mesonephric nephron development", "d": ["The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010752", "l": "regulation of cGMP-mediated signaling", "d": ["Any process that modulates the rate, frequency or extent of cGMP-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002732", "l": "positive regulation of dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160068", "l": "negative regulation of pollen tube guidance", "d": ["Any process that decreases the rate, frequency or extent of pollen tube guidance towards ovules. 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The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.152088137740293", "identifiers": [{"i": "GO:0043934", "l": "sporulation", "d": ["The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0006030", "l": "chitin metabolic process", "d": ["The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031077", "l": "post-embryonic camera-type eye development", "d": ["The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.152088137740293", "identifiers": [{"i": "GO:0002437", "l": "inflammatory response to antigenic stimulus", "d": ["An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045575", "l": "basophil activation", "d": ["The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060408", "l": "regulation of acetylcholine metabolic process", "d": ["Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. 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The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099549", "l": "trans-synaptic signaling by carbon monoxide", "d": ["Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045699", "l": "positive regulation of synergid differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of synergid cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905355", "l": "spine apparatus assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a spine apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006498", "l": "N-terminal protein lipidation", "d": ["The covalent attachment of a lipid group to the amino terminus of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0030595", "l": "leukocyte chemotaxis", "d": ["The movement of a leukocyte in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044511", "l": "envenomation resulting in modulation of receptor activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0015884", "l": "folic acid transport", "d": ["The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060231", "l": "mesenchymal to epithelial transition", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901344", "l": "response to leptomycin B", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009688", "l": "abscisic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903953", "l": "negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000101", "l": "regulation of mammary stem cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of mammary stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046679", "l": "response to streptomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0031016", "l": "pancreas development", "d": ["The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905149", "l": "positive regulation of smooth muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070071", "l": "proton-transporting two-sector ATPase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:1905330", "l": "regulation of morphogenesis of an epithelium", "d": ["Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060436", "l": "bronchiole morphogenesis", "d": ["The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061158", "l": "3'-UTR-mediated mRNA destabilization", "d": ["An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0040027", "l": "negative regulation of vulval development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099502", "l": "calcium-dependent activation of synaptic vesicle fusion", "d": ["The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045222", "l": "CD4 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048620", "l": "post-embryonic hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062041", "l": "positive regulation of meiotic sister chromatid arm separation", "d": ["Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0018143", "l": "nucleic acid-protein covalent cross-linking", "d": ["The formation of a covalent cross-link between a nucleic acid and a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098671", "l": "adhesion receptor-mediated virion attachment to host cell", "d": ["The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900593", "l": "violaceol II biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of violaceol II."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042994", "l": "cytoplasmic sequestering of transcription factor", "d": ["The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905462", "l": "regulation of DNA duplex unwinding", "d": ["Any process that modulates the frequency, rate or extent of DNA duplex unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0015995", "l": "chlorophyll biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905190", "l": "negative regulation of metaphase/anaphase transition of meiosis II", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.524735720299773", "identifiers": [{"i": "GO:0009581", "l": "detection of external stimulus", "d": ["The series of events in which an external stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900242", "l": "regulation of synaptic vesicle endocytosis", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140374", "l": "antiviral innate immune response", "d": ["A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030710", "l": "regulation of border follicle cell delamination", "d": ["Any process that regulates the frequency, rate or extent of border cell delamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000299", "l": "negative regulation of Rho-dependent protein serine/threonine kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032644", "l": "regulation of fractalkine production", "d": ["Any process that modulates the frequency, rate, or extent of fractalkine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0000321", "l": "re-entry into mitotic cell cycle after pheromone arrest", "d": ["The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019227", "l": "neuronal action potential propagation", "d": ["The propagation of an action potential along an axon, away from the soma."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090368", "l": "regulation of ornithine metabolic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002246", "l": "wound healing involved in inflammatory response", "d": ["The series of events that restore integrity to damaged tissue that contribute to an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002050", "l": "pyoverdine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0010952", "l": "positive regulation of peptidase activity", "d": ["Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905097", "l": "regulation of guanyl-nucleotide exchange factor activity", "d": ["Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051512", "l": "positive regulation of unidimensional cell growth", "d": ["Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000303", "l": "regulation of ceramide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010366", "l": "negative regulation of ethylene biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000720", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001045", "l": "negative regulation of integrin-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0044362", "l": "negative regulation of molecular function in another organism", "d": ["Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0051926", "l": "negative regulation of calcium ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019530", "l": "taurine metabolic process", "d": ["The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060143", "l": "positive regulation of syncytium formation by plasma membrane fusion", "d": ["Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018881", "l": "bromoxynil metabolic process", "d": ["The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000088", "l": "negative regulation of mesonephric glomerulus development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000348", "l": "mRNA branch site recognition", "d": ["Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051919", "l": "positive regulation of fibrinolysis", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0044826", "l": "viral genome integration into host DNA", "d": ["The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905412", "l": "negative regulation of mitotic cohesin loading", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0061642", "l": "chemoattraction of axon", "d": ["The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090561", "l": "nuclear migration during mitotic telophase", "d": ["The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0042747", "l": "circadian sleep/wake cycle, REM sleep", "d": ["A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031000", "l": "response to caffeine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072470", "l": "response to cell size control checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of cell size control checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045883", "l": "positive regulation of sulfur utilization", "d": ["Any process that activates or increases the frequency, rate or extent of sulfur utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0009699", "l": "phenylpropanoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032869", "l": "cellular response to insulin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0052027", "l": "perturbation of host signal transduction pathway", "d": ["A process in which a symbiont alters or subverts a signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001005", "l": "positive regulation of pectin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of pectin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903183", "l": "negative regulation of SUMO transferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032979", "l": "protein insertion into mitochondrial inner membrane from matrix", "d": ["The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003191", "l": "coronary sinus valve formation", "d": ["The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046185", "l": "aldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070154", "l": "mitochondrial lysyl-tRNA aminoacylation", "d": ["The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006682", "l": "galactosylceramide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075318", "l": "regulation of ascus development", "d": ["Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018910", "l": "benzene metabolic process", "d": ["The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901778", "l": "pentalenolactone metabolic process", "d": ["The chemical reactions and pathways involving pentalenolactone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904897", "l": "regulation of hepatic stellate cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0072172", "l": "mesonephric tubule formation", "d": ["The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003380", "l": "establishment or maintenance of cytoskeleton polarity involved in gastrulation", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0031923", "l": "pyridoxine transport", "d": ["The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061270", "l": "mesonephric intraglomerular mesangial cell proliferation", "d": ["The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072044", "l": "collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903895", "l": "negative regulation of IRE1-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042352", "l": "GDP-L-fucose salvage", "d": ["The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0003085", "l": "negative regulation of systemic arterial blood pressure", "d": ["The process that reduces the force with which blood travels through the systemic arterial circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051044", "l": "positive regulation of membrane protein ectodomain proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043685", "l": "conversion of glutamyl-tRNA to glutaminyl-tRNA", "d": ["The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032260", "l": "response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010715", "l": "regulation of extracellular matrix disassembly", "d": ["Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106005", "l": "RNA 5'-cap (guanine-N7)-methylation", "d": ["The process whereby a guanine in 5-cap is methylated at the N7 position of guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051764", "l": "actin crosslink formation", "d": ["The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902443", "l": "negative regulation of ripoptosome assembly involved in necroptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901305", "l": "negative regulation of spermidine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010186", "l": "positive regulation of cellular defense response", "d": ["Any process that activates or increases the frequency, rate or extent of cellular defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006106", "l": "fumarate metabolic process", "d": ["The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009217", "l": "purine deoxyribonucleoside triphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045919", "l": "positive regulation of cytolysis", "d": ["Any process that activates or increases the frequency, rate or extent of cytolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0072114", "l": "pronephros morphogenesis", "d": ["The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903842", "l": "response to arsenite ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048570", "l": "notochord morphogenesis", "d": ["The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905745", "l": "negative regulation of mRNA cis splicing, via spliceosome", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0039694", "l": "viral RNA genome replication", "d": ["The replication of a viral RNA genome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044829", "l": "positive regulation by host of viral genome replication", "d": ["A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042663", "l": "regulation of endodermal cell fate specification", "d": ["Any process that mediates the specification of a cell into an endoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042362", "l": "fat-soluble vitamin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035205", "l": "positive regulation of lamellocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000476", "l": "positive regulation of opioid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0046120", "l": "deoxyribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007075", "l": "positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072141", "l": "renal interstitial fibroblast development", "d": ["The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904206", "l": "positive regulation of skeletal muscle hypertrophy", "d": ["Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140887", "l": "positive regulation of nucleosome disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of the controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902846", "l": "positive regulation of mitotic spindle elongation", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0021952", "l": "central nervous system projection neuron axonogenesis", "d": ["Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060210", "l": "metestrus", "d": ["The estrous cycle phase in which there is subsiding follicular function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901121", "l": "tobramycin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tobramycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0010458", "l": "exit from mitosis", "d": ["The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052321", "l": "negative regulation of phytoalexin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009730", "l": "detection of carbohydrate stimulus", "d": ["The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072137", "l": "condensed mesenchymal cell proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042483", "l": "negative regulation of odontogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006359", "l": "regulation of transcription by RNA polymerase III", "d": ["Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003362", "l": "noradrenergic neuron fate commitment involved in brainstem development", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.73602946617558", "identifiers": [{"i": "GO:0040034", "l": "regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000284", "l": "positive regulation of amino acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.411932347165482", "identifiers": [{"i": "GO:0051128", "l": "regulation of cellular component organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904236", "l": "negative regulation of substrate-dependent cell migration, cell attachment to substrate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901012", "l": "(S)-reticuline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (S)-reticuline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018162", "l": "peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine", "d": ["The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905664", "l": "regulation of calcium ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033476", "l": "indoleacetic acid ester conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0034377", "l": "plasma lipoprotein particle assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0086029", "l": "Purkinje myocyte to ventricular cardiac muscle cell signaling", "d": ["Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032756", "l": "positive regulation of interleukin-7 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-7 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902785", "l": "cellular response to undecane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900828", "l": "D-tyrosine metabolic process", "d": ["The chemical reactions and pathways involving D-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0042174", "l": "negative regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902085", "l": "fumagillin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fumagillin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098864", "l": "stabilization of host tight cell-cell junction", "d": ["The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901914", "l": "negative regulation of capsule organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905366", "l": "negative regulation of intralumenal vesicle formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901882", "l": "4-hydroxycoumarin metabolic process", "d": ["The chemical reactions and pathways involving 4-hydroxycoumarin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060390", "l": "regulation of SMAD protein signal transduction", "d": ["Any process that modulates the rate, frequency or extent of SMAD protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905218", "l": "cellular response to astaxanthin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045689", "l": "negative regulation of antipodal cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0036037", "l": "CD8-positive, alpha-beta T cell activation", "d": ["The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010919", "l": "regulation of inositol phosphate biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1901880", "l": "negative regulation of protein depolymerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048942", "l": "posterior lateral line nerve glial cell morphogenesis involved in differentiation", "d": ["The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045428", "l": "regulation of nitric oxide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009964", "l": "negative regulation of flavonoid biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905851", "l": "negative regulation of backward locomotion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034052", "l": "positive regulation of plant-type hypersensitive response", "d": ["Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.815485452747296", "identifiers": [{"i": "GO:0014046", "l": "dopamine secretion", "d": ["The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901418", "l": "positive regulation of response to ethanol", "d": ["Any process that activates or increases the frequency, rate or extent of response to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061367", "l": "behavioral response to acetic acid induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902619", "l": "regulation of microtubule minus-end binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule minus-end binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0000966", "l": "RNA 5'-end processing", "d": ["Any process involved in forming the mature 5' end of an RNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060446", "l": "branching involved in open tracheal system development", "d": ["The process in which the anatomical structures of branches in the open tracheal system are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070153", "l": "mitochondrial leucyl-tRNA aminoacylation", "d": ["The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050940", "l": "regulation of late stripe melanocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0001959", "l": "regulation of cytokine-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902964", "l": "positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060723", "l": "regulation of cell proliferation involved in embryonic placenta development", "d": ["Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048693", "l": "regulation of collateral sprouting of injured axon", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0031400", "l": "negative regulation of protein modification process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032423", "l": "regulation of mismatch repair", "d": ["Any process that modulates the frequency, rate or extent of mismatch repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010607", "l": "negative regulation of cytoplasmic mRNA processing body assembly", "d": ["Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046117", "l": "queuosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010520", "l": "regulation of reciprocal meiotic recombination", "d": ["Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072739", "l": "response to anisomycin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030220", "l": "platelet formation", "d": ["The process in which platelets bud from long processes extended by megakaryocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035158", "l": "regulation of tube diameter, open tracheal system", "d": ["Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035001", "l": "dorsal trunk growth, open tracheal system", "d": ["Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030495", "l": "bacteriochlorophyll catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0098704", "l": "carbohydrate import across plasma membrane", "d": ["The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097340", "l": "inhibition of cysteine-type endopeptidase activity", "d": ["Any process that prevents the activation of an inactive cysteine-type endopeptidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.230470622368927", "identifiers": [{"i": "GO:0021915", "l": "neural tube development", "d": ["The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001744", "l": "insect visual primordium formation", "d": ["Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007454", "l": "labial disc morphogenesis", "d": ["The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990688", "l": "Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane", "d": ["The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902207", "l": "positive regulation of interleukin-2-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1902904", "l": "negative regulation of supramolecular fiber organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:1904951", "l": "positive regulation of establishment of protein localization", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of protein localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0007133", "l": "meiotic anaphase I", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0045931", "l": "positive regulation of mitotic cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110010", "l": "basolateral protein secretion", "d": ["The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002545", "l": "chronic inflammatory response to non-antigenic stimulus", "d": ["A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046463", "l": "acylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034258", "l": "nicotinamide riboside transport", "d": ["The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046166", "l": "glyceraldehyde-3-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021718", "l": "superior olivary nucleus development", "d": ["The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902949", "l": "positive regulation of tau-protein kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990264", "l": "peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity", "d": ["Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0040031", "l": "snRNA modification", "d": ["The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003282", "l": "ventricular septum intermedium development", "d": ["The progression of the ventricular septum intermedium over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901909", "l": "diadenosine hexaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033390", "l": "putrescine biosynthetic process from arginine via N-carbamoylputrescine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003086", "l": "regulation of systemic arterial blood pressure by local renal renin-angiotensin", "d": ["The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0035850", "l": "epithelial cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016240", "l": "autophagosome membrane docking", "d": ["The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046723", "l": "malic acid secretion", "d": ["The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097308", "l": "cellular response to farnesol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901405", "l": "negative regulation of tetrapyrrole catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032834", "l": "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901041", "l": "positive regulation of peptide antigen transport", "d": ["Any process that activates or increases the frequency, rate or extent of peptide antigen transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010130", "l": "anaerobic ethylbenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0097006", "l": "regulation of plasma lipoprotein particle levels", "d": ["Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010125", "l": "mycothiol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902436", "l": "negative regulation of male mating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990396", "l": "single-strand break repair via homologous recombination", "d": ["The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042304", "l": "regulation of fatty acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045604", "l": "regulation of epidermal cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072213", "l": "metanephric capsule development", "d": ["The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071801", "l": "regulation of podosome assembly", "d": ["Any process that modulates the frequency, rate or extent of podosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903168", "l": "positive regulation of pyrroline-5-carboxylate reductase activity", "d": ["Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019261", "l": "1,4-dichlorobenzene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110117", "l": "positive regulation of compound eye photoreceptor cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018009", "l": "N-terminal peptidyl-L-cysteine N-palmitoylation", "d": ["The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071985", "l": "multivesicular body sorting pathway", "d": ["A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035037", "l": "sperm entry", "d": ["An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070350", "l": "regulation of white fat cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of white fat cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006788", "l": "heme oxidation", "d": ["The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003327", "l": "type B pancreatic cell fate commitment", "d": ["The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903102", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044181", "l": "filamentous growth of a multicellular organism", "d": ["The process in which a multicellular organism grows in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070242", "l": "thymocyte apoptotic process", "d": ["Any apoptotic process in a thymocyte, an immature T cell located in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0018352", "l": "protein-pyridoxal-5-phosphate linkage", "d": ["The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0086065", "l": "cell communication involved in cardiac conduction", "d": ["Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.453592996529309", "identifiers": [{"i": "GO:0061138", "l": "morphogenesis of a branching epithelium", "d": ["The process in which the anatomical structures of a branched epithelium are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900035", "l": "negative regulation of cellular response to heat", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0072426", "l": "response to G2 DNA damage checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150075", "l": "negative regulation of protein-glutamine gamma-glutamyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0002385", "l": "mucosal immune response", "d": ["An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045759", "l": "negative regulation of action potential", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046379", "l": "extracellular polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving polysaccharides used in extracellular structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060930", "l": "sinoatrial node cell fate commitment", "d": ["The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902076", "l": "regulation of lateral motor column neuron migration", "d": ["Any process that modulates the frequency, rate or extent of lateral motor column neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060484", "l": "lung-associated mesenchyme development", "d": ["The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042664", "l": "negative regulation of endodermal cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from specifying into an endoderm cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0099638", "l": "endosome to plasma membrane protein transport", "d": ["The directed movement of proteins from the endosome to the plasma membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010042", "l": "response to manganese ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901189", "l": "positive regulation of ephrin receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.163959742754642", "identifiers": [{"i": "GO:0016447", "l": "somatic recombination of immunoglobulin gene segments", "d": ["The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001132", "l": "methane biosynthetic process from 3-(methylthio)propionic acid", "d": ["The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902604", "l": "p-aminobenzoyl-glutamate transmembrane transport", "d": ["The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043568", "l": "positive regulation of insulin-like growth factor receptor signaling pathway", "d": ["Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032974", "l": "amino acid transmembrane export from vacuole", "d": ["The directed movement of amino acids out of the vacuole, across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002487", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045004", "l": "DNA replication proofreading", "d": ["Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0015816", "l": "glycine transport", "d": ["The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034203", "l": "glycolipid translocation", "d": ["The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905027", "l": "regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039574", "l": "disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity", "d": ["Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0030950", "l": "establishment or maintenance of actin cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901256", "l": "regulation of macrophage colony-stimulating factor production", "d": ["Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0018948", "l": "xylene metabolic process", "d": ["The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044597", "l": "daunorubicin metabolic process", "d": ["The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008583", "l": "mystery cell differentiation", "d": ["The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003284", "l": "septum primum development", "d": ["The progression of the septum primum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060644", "l": "mammary gland epithelial cell differentiation", "d": ["The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072143", "l": "mesangial cell development", "d": ["The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014036", "l": "neural crest cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.577556932535018", "identifiers": [{"i": "GO:0001709", "l": "cell fate determination", "d": ["The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904045", "l": "cellular response to aldosterone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003161", "l": "cardiac conduction system development", "d": ["The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900322", "l": "negative regulation of maltotetraose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:2001258", "l": "negative regulation of cation channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009635", "l": "response to herbicide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0010324", "l": "membrane invagination", "d": ["The infolding of a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046543", "l": "development of secondary female sexual characteristics", "d": ["The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000560", "l": "positive regulation of CD24 production", "d": ["Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030043", "l": "actin filament fragmentation", "d": ["The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001281", "l": "regulation of muscle cell chemotaxis toward tendon cell", "d": ["Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044850", "l": "menstrual cycle", "d": ["A type of ovulation cycle where the endometrium is shed if pregnancy does not occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097095", "l": "frontonasal suture morphogenesis", "d": ["The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0150178", "l": "regulation of phosphatidylserine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097339", "l": "glycolate transmembrane transport", "d": ["The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031953", "l": "negative regulation of protein autophosphorylation", "d": ["Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075293", "l": "response to host pH environment", "d": ["Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902848", "l": "negative regulation of neuronal signal transduction", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018989", "l": "apolysis", "d": ["The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072196", "l": "proximal/distal pattern formation involved in pronephric nephron development", "d": ["The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036150", "l": "phosphatidylserine acyl-chain remodeling", "d": ["Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035292", "l": "specification of segmental identity, trunk", "d": ["The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905609", "l": "positive regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000989", "l": "negative regulation of hemicellulose catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904200", "l": "iodide transmembrane transport", "d": ["The process in which iodide is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032901", "l": "positive regulation of neurotrophin production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0008211", "l": "glucocorticoid metabolic process", "d": ["The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901315", "l": "negative regulation of histone H2A K63-linked ubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901540", "l": "ent-pimara-8(14),15-diene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061940", "l": "regulation of c-di-GMP signaling", "d": ["Any process that modulates the rate frequency or extent of c-di-GMP signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009904", "l": "chloroplast accumulation movement", "d": ["The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.63134278132528", "identifiers": [{"i": "GO:0006338", "l": "chromatin remodeling", "d": ["A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902620", "l": "positive regulation of microtubule minus-end binding", "d": ["Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021821", "l": "negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination", "d": ["The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903251", "l": "multi-ciliated epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009181", "l": "purine ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033465", "l": "cis-zeatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903378", "l": "positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141088", "l": "symbiont-mediated activation of host autophagy", "d": ["A process in which a symbiont initiates, promotes, or enhances the activation of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019532", "l": "oxalate transport", "d": ["The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031654", "l": "regulation of heat dissipation", "d": ["Any process that modulates the rate or extent of heat dissipation."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.492932992387935", "identifiers": [{"i": "GO:0000003", "l": "reproduction", "d": ["The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045838", "l": "positive regulation of membrane potential", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045059", "l": "positive thymic T cell selection", "d": ["The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0016321", "l": "female meiosis chromosome segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0002327", "l": "immature B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an immature B cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901367", "l": "response to L-cysteine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0150003", "l": "regulation of spontaneous synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033085", "l": "negative regulation of T cell differentiation in thymus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106081", "l": "maltose import across plasma membrane", "d": ["The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051468", "l": "detection of glucocorticoid hormone stimulus", "d": ["The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001945", "l": "lymph vessel development", "d": ["The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002748", "l": "antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen", "d": ["Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051104", "l": "DNA-dependent DNA replication DNA ligation", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903235", "l": "positive regulation of calcium ion-dependent exocytosis of neurotransmitter", "d": ["Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900124", "l": "negative regulation of nodal receptor complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905151", "l": "negative regulation of voltage-gated sodium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0090033", "l": "positive regulation of filamentous growth", "d": ["Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000078", "l": "positive regulation of type B pancreatic cell development", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic B cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0006493", "l": "protein O-linked glycosylation", "d": ["A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019388", "l": "galactose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0006085", "l": "acetyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045470", "l": "R8 cell-mediated photoreceptor organization", "d": ["The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000100", "l": "regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060060", "l": "post-embryonic retina morphogenesis in camera-type eye", "d": ["The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106380", "l": "purine ribonucleotide salvage", "d": ["Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002895", "l": "regulation of central B cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of central B cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075118", "l": "perturbation of host G protein-coupled receptor signal transduction pathway", "d": ["Any process in which the symbiont alters a host G protein-coupled receptor signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905400", "l": "negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008055", "l": "ocellus pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120058", "l": "positive regulation of small intestinal transit", "d": ["Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0022037", "l": "metencephalon development", "d": ["The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022009", "l": "central nervous system vasculogenesis", "d": ["The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051976", "l": "lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048330", "l": "positive regulation of axial mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0120027", "l": "regulation of osmosensory signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of osmosensory signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048390", "l": "intermediate mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the intermediate mesoderm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009265", "l": "2'-deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0045744", "l": "negative regulation of G protein-coupled receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019303", "l": "D-ribose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990068", "l": "seed dehydration", "d": ["The seed development process whose outcome is the drying of a maturing seed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001561", "l": "fatty acid alpha-oxidation", "d": ["A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070126", "l": "mitochondrial translational termination", "d": ["The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035865", "l": "cellular response to potassium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006603", "l": "phosphocreatine metabolic process", "d": ["The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904357", "l": "negative regulation of telomere maintenance via telomere lengthening", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902855", "l": "regulation of non-motile cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of non-motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904508", "l": "regulation of protein localization to basolateral plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903218", "l": "regulation of malate dehydrogenase (decarboxylating) (NADP+) activity", "d": ["Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902744", "l": "negative regulation of lamellipodium organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903287", "l": "negative regulation of potassium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046008", "l": "regulation of female receptivity, post-mating", "d": ["Any process that modulates the receptiveness of a female to male advances subsequent to mating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902386", "l": "glycyrrhetinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycyrrhetinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035011", "l": "melanotic encapsulation of foreign target", "d": ["Formation of a multilayered, melanized sheath of cells around a foreign invader."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031449", "l": "regulation of slow-twitch skeletal muscle fiber contraction", "d": ["Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905916", "l": "negative regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032373", "l": "positive regulation of sterol transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098911", "l": "regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. 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{"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033492", "l": "esculetin metabolic process", "d": ["The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090615", "l": "mitochondrial mRNA processing", "d": ["Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051644", "l": "plastid localization", "d": ["Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000330", "l": "positive regulation of T-helper 17 cell lineage commitment", "d": ["Any process that activates or increases the frequency, rate or extent of 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"81.247621244257502", "identifiers": [{"i": "GO:0044038", "l": "cell wall macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990556", "l": "mitochondrial isopropylmalate transmembrane transport", "d": ["The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990170", "l": "stress response to cadmium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0008589", "l": "regulation of smoothened signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of smoothened signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048090", "l": "negative regulation of female pigmentation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097624", "l": "UDP-galactose transmembrane import into Golgi lumen", "d": ["The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007079", "l": "mitotic chromosome movement towards spindle pole", "d": ["The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902120", "l": "negative regulation of meiotic spindle elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900017", "l": "positive regulation of cytokine production involved in inflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043552", "l": "positive regulation of phosphatidylinositol 3-kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070958", "l": "negative regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0007411", "l": "axon guidance", "d": ["The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0009116", "l": "nucleoside metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061076", "l": "negative regulation of neural retina development", "d": ["Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902221", "l": "erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033625", "l": "positive regulation of integrin activation", "d": ["Any process that activates or increases the frequency, rate, or extent of integrin activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051417", "l": "microtubule nucleation by spindle pole body", "d": ["The 'de novo' formation of a microtubule, mediated by the spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015974", "l": "guanosine pentaphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903333", "l": "negative regulation of protein folding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "43.651882686219452", "identifiers": [{"i": "GO:0007600", "l": "sensory perception", "d": ["The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. 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Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034124", "l": "regulation of MyD88-dependent toll-like receptor signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1901463", "l": "regulation of tetrapyrrole biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0086069", "l": "bundle of His cell to Purkinje myocyte communication", "d": ["The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072316", "l": "alpha-glucan catabolic process involved in ascospore release from ascus", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019697", "l": "L-xylitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002436", "l": "immune complex clearance by monocytes and macrophages", "d": ["The process of immune complex clearance by monocytes or macrophages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035853", "l": "chromosome passenger complex localization to spindle midzone", "d": ["A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042212", "l": "cresol metabolic process", "d": ["The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.75272396535307", "identifiers": [{"i": "GO:1905508", "l": "protein localization to microtubule organizing center", "d": ["A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010272", "l": "response to silver ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038013", "l": "positive regulation of Wnt signaling pathway by Wnt receptor internalization", "d": ["Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075019", "l": "negative regulation of appressorium formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900178", "l": "negative regulation of aflatoxin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021886", "l": "hypothalamus gonadotrophin-releasing hormone neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045607", "l": "regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of auditory hair cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0046148", "l": "pigment biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002131", "l": "wobble position cytosine ribose methylation", "d": ["The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090403", "l": "oxidative stress-induced premature senescence", "d": ["A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000226", "l": "regulation of pancreatic A cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010954", "l": "positive regulation of protein processing", "d": ["Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007558", "l": "regulation of juvenile hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of juvenile hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140961", "l": "cellular detoxification of metal ion", "d": ["Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085015", "l": "dormancy maintenance of symbiont in host", "d": ["Any process in which a dormant state is maintained by the symbiont within the host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901456", "l": "positive regulation of response to toluene", "d": ["Any process that activates or increases the frequency, rate or extent of response to toluene."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043419", "l": "urea catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0008355", "l": "olfactory learning", "d": ["Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000268", "l": "positive regulation of blood coagulation, intrinsic pathway", "d": ["Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044591", "l": "response to amylopectin", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0010717", "l": "regulation of epithelial to mesenchymal transition", "d": ["Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. 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This is essential for efficient flow of gases through the tracheal network."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019621", "l": "creatinine catabolic process to formate", "d": ["The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900316", "l": "negative regulation of maltopentaose transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014710", "l": "negative regulation of somitomeric trunk muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110076", "l": "negative regulation of ferroptosis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902520", "l": "response to doxorubicin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039665", "l": "permeabilization of host organelle membrane involved in viral entry into host cell", "d": ["Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903800", "l": "positive regulation of miRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905737", "l": "positive regulation of L-proline import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099578", "l": "regulation of translation at postsynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008362", "l": "chitin-based embryonic cuticle biosynthetic process", "d": ["Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902152", "l": "positive regulation of response to DNA integrity checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000843", "l": "regulation of testosterone secretion", "d": ["Any process that modulates the frequency, rate or extent of testosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048824", "l": "pigment cell precursor differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor."]}]} {"type": "biolink:BiologicalProcess", "ic": "36.481291867264524", "identifiers": [{"i": "GO:0007399", "l": "nervous system development", "d": ["The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002747", "l": "antigen processing and presentation following phagocytosis", "d": ["Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0007000", "l": "nucleolus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002805", "l": "regulation of antimicrobial peptide biosynthetic process", "d": ["Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018949", "l": "m-xylene metabolic process", "d": ["The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0052155", "l": "perturbation of host cell-mediated immune response", "d": ["A process in which an organism effects a change that affects cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044485", "l": "envenomation resulting in fibrinogenolysis in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019294", "l": "keto-3-deoxy-D-manno-octulosonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009398", "l": "FMN biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061444", "l": "endocardial cushion cell development", "d": ["The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.748105804263417", "identifiers": [{"i": "GO:0051098", "l": "regulation of binding", "d": ["Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904192", "l": "regulation of cholangiocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003353", "l": "positive regulation of cilium movement", "d": ["Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036246", "l": "phytochelatin 2 import into vacuole", "d": ["The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150158", "l": "positive regulation of interleukin-34 production", "d": ["Any process that activates or increases the frequency, rate or extent of interleukin-34 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039520", "l": "induction by virus of host autophagy", "d": ["Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0099703", "l": "induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration", "d": ["The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. 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Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018154", "l": "peptide cross-linking via (2R,6R)-lanthionine", "d": ["The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006183", "l": "GTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000434", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter by galactose", "d": ["Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0086018", "l": "SA node cell to atrial cardiac muscle cell signaling", "d": ["Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035360", "l": "positive regulation of peroxisome proliferator activated receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000201", "l": "negative regulation of ribosomal subunit export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019624", "l": "atrazine catabolic process to isopropylamine", "d": ["The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900978", "l": "negative regulation of tatiopterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002630", "l": "positive regulation of proteolysis associated with antigen processing and presentation", "d": ["Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035518", "l": "histone H2A monoubiquitination", "d": ["The modification of histone H2A by addition of a single ubiquitin group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033590", "l": "response to cobalamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905792", "l": "positive regulation of mechanosensory behavior", "d": ["Any process that activates or increases the frequency, rate or extent of mechanosensory behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042140", "l": "late meiotic recombination nodule assembly", "d": ["During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0050952", "l": "sensory perception of electrical stimulus", "d": ["The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0060536", "l": "cartilage morphogenesis", "d": ["The process in which the anatomical structures of cartilage are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007522", "l": "visceral muscle development", "d": ["The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033325", "l": "choline biosynthetic process via phosphoryl-ethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900369", "l": "negative regulation of post-transcriptional gene silencing by regulatory ncRNA", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110018", "l": "cap-independent translational initiation of circular RNA", "d": ["The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061639", "l": "Cdv-dependent cytokinesis", "d": ["A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009195", "l": "pyrimidine ribonucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0009595", "l": "detection of biotic stimulus", "d": ["The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003147", "l": "neural crest cell migration involved in heart formation", "d": ["The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046315", "l": "phosphocreatine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046520", "l": "sphingoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035505", "l": "positive regulation of myosin light chain kinase activity", "d": ["Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0018933", "l": "nicotine metabolic process", "d": ["The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.70470389845471", "identifiers": [{"i": "GO:0001958", "l": "endochondral ossification", "d": ["Replacement ossification wherein bone tissue replaces cartilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032685", "l": "negative regulation of granulocyte macrophage colony-stimulating factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070444", "l": "oligodendrocyte progenitor proliferation", "d": ["The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106280", "l": "positive regulation of UDP-N-acetylglucosamine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0005997", "l": "xylulose metabolic process", "d": ["The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044395", "l": "protein targeting to vacuolar membrane", "d": ["The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090036", "l": "regulation of protein kinase C signaling", "d": ["Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0019835", "l": "cytolysis", "d": ["The rupture of cell membranes and the loss of cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001802", "l": "type III hypersensitivity", "d": ["An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903595", "l": "positive regulation of histamine secretion by mast cell", "d": ["Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901001", "l": "negative regulation of response to salt stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000903", "l": "cellooligosaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0046578", "l": "regulation of Ras protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Ras protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070358", "l": "actin polymerization-dependent cell motility", "d": ["A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002439", "l": "chronic inflammatory response to antigenic stimulus", "d": ["A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900477", "l": "negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051914", "l": "positive regulation of synaptic plasticity by chemical substance", "d": ["The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904386", "l": "response to L-phenylalanine derivative", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0099117", "l": "protein transport along microtubule to cell tip", "d": ["The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042422", "l": "norepinephrine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061332", "l": "Malpighian tubule bud morphogenesis", "d": ["The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019338", "l": "pentachlorophenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901406", "l": "positive regulation of tetrapyrrole catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071480", "l": "cellular response to gamma radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0035882", "l": "defecation rhythm", "d": ["The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.898660913853604", "identifiers": [{"i": "GO:0050886", "l": "endocrine process", "d": ["The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060830", "l": "ciliary receptor clustering involved in smoothened signaling pathway", "d": ["Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140204", "l": "pyridoxal import across plasma membrane", "d": ["The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0061687", "l": "detoxification of inorganic compound", "d": ["Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034411", "l": "cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:1903510", "l": "mucopolysaccharide metabolic process", "d": ["The chemical reactions and pathways involving mucopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120235", "l": "regulation of post-translational protein targeting to membrane, translocation", "d": ["Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009088", "l": "threonine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0016188", "l": "synaptic vesicle maturation", "d": ["Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006102", "l": "isocitrate metabolic process", "d": ["The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000890", "l": "cellodextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a cellodextrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003104", "l": "positive regulation of glomerular filtration", "d": ["Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021830", "l": "interneuron migration from the subpallium to the cortex", "d": ["The directed movement of interneurons from the subpallium to the cortex during forebrain development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045606", "l": "positive regulation of epidermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904815", "l": "negative regulation of protein localization to chromosome, telomeric region", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006048", "l": "UDP-N-acetylglucosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902844", "l": "positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway", "d": ["A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904407", "l": "positive regulation of nitric oxide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0072377", "l": "blood coagulation, common pathway", "d": ["A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0015878", "l": "biotin transport", "d": ["The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080119", "l": "ER body organization", "d": ["A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903796", "l": "negative regulation of inorganic anion transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0014904", "l": "myotube cell development", "d": ["The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902527", "l": "positive regulation of protein monoubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein monoubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090506", "l": "axillary shoot meristem initiation", "d": ["A developmental process that results in the initiation of an axillary shoot meristem. 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"identifiers": [{"i": "GO:0006469", "l": "negative regulation of protein kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070755", "l": "negative regulation of interleukin-35 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0034605", "l": "cellular response to heat", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062089", "l": "regulation of taurine biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of taurine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0072655", "l": "establishment of protein localization to mitochondrion", "d": ["The directed movement of a protein to the mitochondrion or a part of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006075", "l": "(1->3)-beta-D-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080192", "l": "primary thickening", "d": ["Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0015804", "l": "neutral amino acid transport", "d": ["The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "51.986287646268401", "identifiers": [{"i": "GO:0010033", "l": "response to organic substance", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019280", "l": "L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine", "d": ["The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043519", "l": "regulation of myosin II filament organization", "d": ["Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904188", "l": "negative regulation of transformation of host cell by virus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070682", "l": "proteasome regulatory particle assembly", "d": ["The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904156", "l": "DN3 thymocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905922", "l": "negative regulation of acetylcholine biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060953", "l": "cardiac glial cell fate commitment", "d": ["The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009562", "l": "embryo sac nuclear migration", "d": ["The directed movement of an embryo sac nucleus to the pole or center of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0085044", "l": "disassembly by symbiont of host cuticle", "d": ["The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090172", "l": "microtubule cytoskeleton organization involved in homologous chromosome segregation", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035521", "l": "monoubiquitinated histone deubiquitination", "d": ["The removal of the ubiquitin group from a monoubiquitinated histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000374", "l": "Group III intron splicing", "d": ["The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009234", "l": "menaquinone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072758", "l": "response to topoisomerase inhibitor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051037", "l": "regulation of transcription involved in meiotic cell cycle", "d": ["Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021622", "l": "oculomotor nerve morphogenesis", "d": ["The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0007405", "l": "neuroblast proliferation", "d": ["The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035297", "l": "regulation of Malpighian tubule diameter", "d": ["Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0033865", "l": "nucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0150200", "l": "regulation of transport across blood-brain barrier", "d": ["Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0019692", "l": "deoxyribose phosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0090075", "l": "relaxation of muscle", "d": ["A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1904948", "l": "midbrain dopaminergic neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071275", "l": "cellular response to aluminum ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072627", "l": "interleukin-28A production", "d": ["The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904146", "l": "positive regulation of meiotic cell cycle process involved in oocyte maturation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905706", "l": "regulation of mitochondrial ATP synthesis coupled proton transport", "d": ["Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.239986017158159", "identifiers": [{"i": "GO:0043393", "l": "regulation of protein binding", "d": ["Any process that modulates the frequency, rate or extent of protein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010836", "l": "negative regulation of protein ADP-ribosylation", "d": ["Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900663", "l": "positive regulation of emericellamide A biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902434", "l": "sulfate import across plasma membrane", "d": ["The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043373", "l": "CD4-positive, alpha-beta T cell lineage commitment", "d": ["The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042215", "l": "anaerobic phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902281", "l": "negative regulation of RNA helicase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001998", "l": "angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure", "d": ["The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009753", "l": "response to jasmonic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036444", "l": "calcium import into the mitochondrion", "d": ["A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043928", "l": "exonucleolytic catabolism of deadenylated mRNA", "d": ["The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0033143", "l": "regulation of intracellular steroid hormone receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0042273", "l": "ribosomal large subunit biogenesis", "d": ["A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140541", "l": "piRNA transcription", "d": ["The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003239", "l": "conus arteriosus morphogenesis", "d": ["The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070397", "l": "wall teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044528", "l": "regulation of mitochondrial mRNA stability", "d": ["Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.511465329959393", "identifiers": [{"i": "GO:0071495", "l": "cellular response to endogenous stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009188", "l": "ribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905432", "l": "regulation of retrograde trans-synaptic signaling by neuropeptide", "d": ["Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009825", "l": "multidimensional cell growth", "d": ["The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032464", "l": "positive regulation of protein homooligomerization", "d": ["Any process that activates or increases the frequency, rate or extent of protein homooligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000752", "l": "agglutination involved in conjugation with cellular fusion", "d": ["The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071694", "l": "maintenance of protein location in extracellular region", "d": ["Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0030653", "l": "beta-lactam antibiotic metabolic process", "d": ["The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.433245225553328", "identifiers": [{"i": "GO:0031347", "l": "regulation of defense response", "d": ["Any process that modulates the frequency, rate or extent of a defense response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002722", "l": "negative regulation of B cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051555", "l": "flavonol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002306", "l": "CD4-positive gamma-delta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060007", "l": "linear vestibuloocular reflex", "d": ["A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905717", "l": "positive regulation of cornification", "d": ["Any process that activates or increases the frequency, rate or extent of cornification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036109", "l": "alpha-linolenic acid metabolic process", "d": ["The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021648", "l": "vestibulocochlear nerve morphogenesis", "d": ["The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903006", "l": "positive regulation of protein K63-linked deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0032438", "l": "melanosome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904633", "l": "regulation of podocyte apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046479", "l": "glycosphingolipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1900704", "l": "regulation of siderophore biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of siderophore biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035089", "l": "establishment of apical/basal cell polarity", "d": ["The specification and formation of the polarity of a cell along its apical/basal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904967", "l": "regulation of spindle attachment to meiosis I kinetochore", "d": ["Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901743", "l": "2-deoxystreptamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038001", "l": "paracrine signaling", "d": ["The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048811", "l": "male analia morphogenesis", "d": ["The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043485", "l": "endosome to pigment granule transport", "d": ["The directed movement of substances from endosomes to pigment granules."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.764608079693332", "identifiers": [{"i": "GO:0098662", "l": "inorganic cation transmembrane transport", "d": ["A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0031103", "l": "axon regeneration", "d": ["The regrowth of axons following their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905100", "l": "regulation of apoptosome assembly", "d": ["Any process that modulates the frequency, rate or extent of apoptosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061271", "l": "mesenchymal to epithelial transition involved in mesonephric renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080033", "l": "response to nitrite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0099135", "l": "chimeric colonial development", "d": ["Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0075286", "l": "regulation of sporangiospore formation", "d": ["Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036077", "l": "intratendonous ossification", "d": ["Ossification wherein bone tissue forms within tendonous tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060386", "l": "synapse assembly involved in innervation", "d": ["The assembly of a synapse within a target tissue in which a nerve is invading."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032652", "l": "regulation of interleukin-1 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055129", "l": "L-proline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072187", "l": "metanephric cap formation", "d": ["The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075331", "l": "negative regulation of arbuscule formation for nutrient acquisition from host", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106122", "l": "negative regulation of cobalamin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0106349", "l": "snRNA methylation", "d": ["The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099575", "l": "regulation of protein catabolic process at presynapse, modulating synaptic transmission", "d": ["Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035192", "l": "nuclear cortical migration", "d": ["The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043318", "l": "negative regulation of cytotoxic T cell degranulation", "d": ["Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903405", "l": "protein localization to nuclear body", "d": ["A process in which a protein is transported to, or maintained in, a location within a nuclear body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003255", "l": "endocardial precursor cell differentiation", "d": ["The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006024", "l": "glycosaminoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0071902", "l": "positive regulation of protein serine/threonine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070898", "l": "RNA polymerase III preinitiation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903645", "l": "negative regulation of chaperone-mediated protein folding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090128", "l": "regulation of synapse maturation", "d": ["Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0099625", "l": "ventricular cardiac muscle cell membrane repolarization", "d": ["The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097248", "l": "maintenance of protein location in cell cortex of cell tip", "d": ["A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900980", "l": "regulation of phenazine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of phenazine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006578", "l": "amino-acid betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032877", "l": "positive regulation of DNA endoreduplication", "d": ["Any process that activates or increases the frequency, rate or extent of DNA endoreduplication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000277", "l": "positive regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072383", "l": "plus-end-directed vesicle transport along microtubule", "d": ["The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0198738", "l": "cell-cell signaling by wnt", "d": ["Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901665", "l": "negative regulation of NAD+ ADP-ribosyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009084", "l": "glutamine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042252", "l": "establishment of planar polarity of larval imaginal disc epithelium", "d": ["Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072246", "l": "metanephric glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060977", "l": "coronary vasculature morphogenesis", "d": ["The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032384", "l": "negative regulation of intracellular cholesterol transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0070525", "l": "tRNA threonylcarbamoyladenosine metabolic process", "d": ["The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035020", "l": "regulation of Rac protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rac protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021904", "l": "dorsal/ventral neural tube patterning", "d": ["The process in which the neural tube is regionalized in the dorsoventral axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035476", "l": "angioblast cell migration", "d": ["The orderly movement of angioblasts, cells involved in blood vessel morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042919", "l": "benzoate transport", "d": ["The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000079", "l": "regulation of cyclin-dependent protein serine/threonine kinase activity", "d": ["Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046626", "l": "regulation of insulin receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of insulin receptor signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002603", "l": "positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018219", "l": "peptidyl-cysteine S-acetylation", "d": ["The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905615", "l": "positive regulation of developmental vegetative growth", "d": ["Any process that activates or increases the frequency, rate or extent of developmental vegetative growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900805", "l": "brevianamide F biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of brevianamide F. Brevianamide F is the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by some fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072229", "l": "metanephric proximal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902109", "l": "negative regulation of mitochondrial membrane permeability involved in apoptotic process", "d": ["Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002590", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014718", "l": "positive regulation of satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010267", "l": "ta-siRNA processing", "d": ["A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000929", "l": "positive regulation of cellodextrin catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0060049", "l": "regulation of protein glycosylation", "d": ["Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140239", "l": "postsynaptic endocytosis", "d": ["A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0048596", "l": "embryonic camera-type eye morphogenesis", "d": ["The process in which the anatomical structures of the eye are generated and organized during embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072335", "l": "regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation", "d": ["Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904056", "l": "positive regulation of cholangiocyte proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018246", "l": "protein-coenzyme A linkage", "d": ["The formation of a linkage between a protein amino acid and coenzyme A."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045800", "l": "negative regulation of chitin-based cuticle tanning", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097043", "l": "histone H3-K56 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015965", "l": "diadenosine tetraphosphate metabolic process", "d": ["The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000379", "l": "tRNA-type intron splice site recognition and cleavage", "d": ["RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071582", "l": "negative regulation of zinc ion transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1903175", "l": "fatty alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fatty alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035080", "l": "heat shock-mediated polytene chromosome puffing", "d": ["The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019543", "l": "propionate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061214", "l": "mesonephric smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905275", "l": "Rohon-Beard neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010587", "l": "miRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010621", "l": "negative regulation of transcription by transcription factor localization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072067", "l": "early distal convoluted tubule development", "d": ["The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048720", "l": "posterior cibarial plate morphogenesis", "d": ["The process in which the anatomical structures of the posterior cibarial plate are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021661", "l": "rhombomere 4 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019081", "l": "viral translation", "d": ["A process by which viral mRNA is translated into viral protein, using the host cellular machinery."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046186", "l": "acetaldehyde biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070537", "l": "histone H2A K63-linked deubiquitination", "d": ["A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904716", "l": "positive regulation of chaperone-mediated autophagy", "d": ["Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002007", "l": "detection of hypoxic conditions in blood by chemoreceptor signaling", "d": ["The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903575", "l": "cornified envelope assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a cornified envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900610", "l": "F-9775A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of F-9775A."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015730", "l": "propanoate transmembrane transport", "d": ["The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003090", "l": "positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine", "d": ["Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075010", "l": "regulation of germ tube formation", "d": ["Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.391713369466018", "identifiers": [{"i": "GO:0042445", "l": "hormone metabolic process", "d": ["The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072147", "l": "glomerular parietal epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060152", "l": "microtubule-based peroxisome localization", "d": ["The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903055", "l": "positive regulation of extracellular matrix organization", "d": ["Any process that activates or increases the frequency, rate or extent of extracellular matrix organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006849", "l": "plasma membrane pyruvate transport", "d": ["The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019552", "l": "glutamate catabolic process via 2-hydroxyglutarate", "d": ["The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0042144", "l": "vacuole fusion, non-autophagic", "d": ["The fusion of two vacuole membranes to form a single vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090513", "l": "L-histidine transmembrane import into vacuole", "d": ["The directed movement of L-histidine into the vacuole across the vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071394", "l": "cellular response to testosterone stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903743", "l": "negative regulation of anterograde synaptic vesicle transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033631", "l": "cell-cell adhesion mediated by integrin", "d": ["The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071416", "l": "cellular response to tropane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030150", "l": "protein import into mitochondrial matrix", "d": ["The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120232", "l": "prenyl-FMNH2 biosynthetic process", "d": ["The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009134", "l": "nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0071867", "l": "response to monoamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902768", "l": "isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0019350", "l": "teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030328", "l": "prenylcysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900442", "l": "positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH", "d": ["Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030103", "l": "vasopressin secretion", "d": ["The regulated release of vasopressin from secretory granules into the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901340", "l": "negative regulation of store-operated calcium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140196", "l": "positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process", "d": ["Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060716", "l": "labyrinthine layer blood vessel development", "d": ["The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033511", "l": "luteolin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018000", "l": "N-terminal peptidyl-tyrosine acetylation", "d": ["The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900680", "l": "positive regulation of ferricrocin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903663", "l": "L-altrarate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-altrarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000248", "l": "negative regulation of establishment or maintenance of neuroblast polarity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905949", "l": "negative regulation of calcium ion import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003047", "l": "regulation of systemic arterial blood pressure by epinephrine", "d": ["The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090043", "l": "regulation of tubulin deacetylation", "d": ["Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0036507", "l": "protein demannosylation", "d": ["The removal of one or more mannose residues from a mannosylated protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097212", "l": "lysosomal membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061722", "l": "sulphoglycolysis", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035561", "l": "regulation of chromatin binding", "d": ["Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900497", "l": "regulation of butyryl-CoA catabolic process to butanol", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051945", "l": "negative regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0008364", "l": "pupal chitin-based cuticle development", "d": ["Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0016180", "l": "snRNA processing", "d": ["Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030999", "l": "linear element assembly", "d": ["The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099152", "l": "regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032147", "l": "activation of protein kinase activity", "d": ["Any process that initiates the activity of an inactive protein kinase."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:1903083", "l": "protein localization to condensed chromosome", "d": ["A process in which a protein is transported to, or maintained in, a location within a condensed chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051016", "l": "barbed-end actin filament capping", "d": ["The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106035", "l": "protein maturation by [4Fe-4S] cluster transfer", "d": ["The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0120256", "l": "olefinic compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C)."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.439063219932727", "identifiers": [{"i": "GO:0010647", "l": "positive regulation of cell communication", "d": ["Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903288", "l": "positive regulation of potassium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000549", "l": "positive regulation of dendritic cell dendrite assembly", "d": ["Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110065", "l": "regulation of interphase mitotic telomere clustering", "d": ["Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019126", "l": "peptidyl-serine racemization", "d": ["The racemization of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051383", "l": "kinetochore organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0042773", "l": "ATP synthesis coupled electron transport", "d": ["The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043637", "l": "puromycin metabolic process", "d": ["The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.25985915845861", "identifiers": [{"i": "GO:0002700", "l": "regulation of production of molecular mediator of immune response", "d": ["Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990669", "l": "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane", "d": ["The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018139", "l": "peptide cross-linking via L-phenylalanine thiazolecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0019068", "l": "virion assembly", "d": ["A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0050931", "l": "pigment cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001098", "l": "tetrasaccharide transport", "d": ["The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0150105", "l": "protein localization to cell-cell junction", "d": ["A process in which a protein is transported to, or maintained, in a location within a cell-cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904276", "l": "regulation of wax biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of wax biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032277", "l": "negative regulation of gonadotropin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000470", "l": "positive regulation of peroxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901127", "l": "candicidin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of candicidin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000091", "l": "negative regulation of mesonephric glomerular mesangial cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990215", "l": "negative regulation by symbiont of host intracellular transport", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000718", "l": "regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097114", "l": "NMDA glutamate receptor clustering", "d": ["The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046461", "l": "neutral lipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036531", "l": "glutathione deglycation", "d": ["The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060439", "l": "trachea morphogenesis", "d": ["The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904118", "l": "regulation of otic vesicle morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000353", "l": "formation of quadruple SL/U4/U5/U6 snRNP", "d": ["Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003332", "l": "negative regulation of extracellular matrix constituent secretion", "d": ["Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080172", "l": "petal epidermis patterning", "d": ["The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006451", "l": "translational readthrough", "d": ["The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051944", "l": "positive regulation of catecholamine uptake involved in synaptic transmission", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.945349939901874", "identifiers": [{"i": "GO:0032989", "l": "cellular component morphogenesis", "d": ["The process in which cellular structures, including whole cells or cell parts, are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001938", "l": "positive regulation of endothelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002938", "l": "tRNA guanine ribose methylation", "d": ["The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002798", "l": "negative regulation of antibacterial peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071580", "l": "regulation of zinc ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904024", "l": "negative regulation of glucose catabolic process to lactate via pyruvate", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045907", "l": "positive regulation of vasoconstriction", "d": ["Any process that activates or increases the frequency, rate or extent of vasoconstriction."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.989777303936307", "identifiers": [{"i": "GO:0061539", "l": "octopamine secretion", "d": ["The controlled release of octopamine by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043308", "l": "eosinophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990210", "l": "positive regulation by symbiont of indole acetic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0120063", "l": "stomach smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903294", "l": "regulation of glutamate secretion, neurotransmission", "d": ["Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990049", "l": "retrograde neuronal dense core vesicle transport", "d": ["The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021934", "l": "hindbrain tangential cell migration", "d": ["The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901168", "l": "3-chlorocatechol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.913786356134864", "identifiers": [{"i": "GO:0003002", "l": "regionalization", "d": ["The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120304", "l": "integument-mediated background adaptation", "d": ["Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010083", "l": "regulation of vegetative meristem growth", "d": ["Any process involved in maintaining the size and shape of a vegetative meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046099", "l": "guanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002368", "l": "B cell cytokine production", "d": ["Any process that contributes to cytokine production by a B cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0015918", "l": "sterol transport", "d": ["The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900481", "l": "negative regulation of diacylglycerol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903889", "l": "negative regulation of plant epidermal cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904960", "l": "positive regulation of cytochrome-c oxidase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055025", "l": "positive regulation of cardiac muscle tissue development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006434", "l": "seryl-tRNA aminoacylation", "d": ["The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098994", "l": "disruption of host cell envelope during viral entry", "d": ["The disruption of host cell envelope by viral proteins during virus entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009805", "l": "coumarin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002604", "l": "regulation of dendritic cell antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000183", "l": "rDNA heterochromatin formation", "d": ["The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010350", "l": "cellular response to magnesium starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072441", "l": "response to meiotic DNA replication checkpoint signaling", "d": ["A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902973", "l": "mitotic DNA replication DNA ligation", "d": ["Any DNA ligation involved in mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905875", "l": "negative regulation of postsynaptic density organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904923", "l": "regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021998", "l": "neural plate mediolateral regionalization", "d": ["The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046213", "l": "methyl ethyl ketone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016546", "l": "male courtship behavior, proboscis-mediated licking", "d": ["The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071731", "l": "response to nitric oxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006409", "l": "tRNA export from nucleus", "d": ["The directed movement of tRNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050676", "l": "negative regulation of urothelial cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0061228", "l": "mesonephric nephron morphogenesis", "d": ["The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010241", "l": "ent-kaurene oxidation to kaurenoic acid", "d": ["The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000597", "l": "positive regulation of optic nerve formation", "d": ["Any process that activates or increases the frequency, rate or extent of optic nerve formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061586", "l": "positive regulation of transcription by transcription factor localization", "d": ["Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071716", "l": "leukotriene transport", "d": ["The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032913", "l": "negative regulation of transforming growth factor beta3 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080183", "l": "response to photooxidative stress", "d": ["Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901785", "l": "p-cresol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-cresol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901097", "l": "negative regulation of autophagosome maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905211", "l": "negative regulation of fibroblast chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0051955", "l": "regulation of amino acid transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904201", "l": "regulation of iodide transport", "d": ["Any process that modulates the frequency, rate or extent of iodide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009047", "l": "dosage compensation by hyperactivation of X chromosome", "d": ["Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060982", "l": "coronary artery morphogenesis", "d": ["The process in which the anatomical structures of coronary arteries are generated and organized. 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This is the final step in metaphase plate congression."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032849", "l": "positive regulation of cellular pH reduction", "d": ["Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034301", "l": "endospore formation", "d": ["The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060018", "l": "astrocyte fate commitment", "d": ["The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900657", "l": "positive regulation of diorcinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072128", "l": "renal capsule morphogenesis", "d": ["The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048363", "l": "mucilage pectin metabolic process", "d": ["The chemical reactions and pathways involving the pectin component of mucilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046230", "l": "2-aminobenzenesulfonate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000092", "l": "mitotic anaphase B", "d": ["The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0032612", "l": "interleukin-1 production", "d": ["The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019926", "l": "peptidyl-tryptophan oxidation to tryptophyl quinone", "d": ["The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000986", "l": "negative regulation of behavioral fear response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070125", "l": "mitochondrial translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140924", "l": "L-kynurenine transmembrane transport", "d": ["The directed movement of L-kynurenine across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035214", "l": "eye-antennal disc development", "d": ["Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035193", "l": "larval central nervous system remodeling", "d": ["Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0002828", "l": "regulation of type 2 immune response", "d": ["Any process that modulates the frequency, rate, or extent of a type 2 immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006696", "l": "ergosterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061566", "l": "CMP phosphorylation", "d": ["The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. 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{"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033227", "l": "dsRNA transport", "d": ["The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106428", "l": "positive regulation of kainate selective glutamate receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0018108", "l": "peptidyl-tyrosine phosphorylation", "d": ["The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001270", "l": "regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis", "d": ["Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0097530", "l": "granulocyte migration", "d": ["The movement of a granulocyte within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905357", "l": "negative regulation of snRNA pseudouridine synthesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.064426759960739", "identifiers": [{"i": "GO:1903825", "l": "organic acid transmembrane transport", "d": ["The process in which an organic acid is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904645", "l": "response to amyloid-beta", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033616", "l": "plasma membrane proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009094", "l": "L-phenylalanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003390", "l": "dendrite development by retrograde extension", "d": ["The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901850", "l": "7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process", "d": ["The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905261", "l": "regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048561", "l": "establishment of 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Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.01750614557713", "identifiers": [{"i": "GO:0002250", "l": "adaptive immune response", "d": ["An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046389", "l": "deoxyribose 5-phosphate metabolic process", "d": ["The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903643", "l": "positive regulation of recombination hotspot binding", "d": ["Any process that activates or increases the frequency, rate or extent of recombination hotspot binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0022904", "l": "respiratory electron transport chain", "d": ["A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901069", "l": "guanosine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046272", "l": "stilbene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042814", "l": "monopolar cell growth", "d": ["Polarized growth from one end of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0098512", "l": "detection of humidity stimulus involved in sensory perception", "d": ["The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060981", "l": "cell migration involved in coronary angiogenesis", "d": ["The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903850", "l": "regulation of cristae formation", "d": ["Any process that modulates the frequency, rate or extent of cristae formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097393", "l": "telomeric repeat-containing RNA transcription", "d": ["The synthesis of telomeric repeat-containing RNA from a DNA template. 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An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.025952377698907", "identifiers": [{"i": "GO:0050982", "l": "detection of mechanical stimulus", "d": ["The series of events by which a mechanical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002238", "l": "response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905796", "l": "regulation of intraciliary anterograde transport", "d": ["Any process that modulates the frequency, rate or extent of intraciliary anterograde transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036364", "l": "transforming growth factor beta1 activation", "d": ["The release of transforming growth factor beta1 (TGF-beta1) from its latent state."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0034341", "l": "response to type II interferon", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048541", "l": "Peyer's patch development", "d": ["The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990297", "l": "renal amino acid absorption", "d": ["A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044807", "l": "macrophage migration inhibitory factor production", "d": ["The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0016575", "l": "histone deacetylation", "d": ["The modification of histones by removal of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0033275", "l": "actin-myosin filament sliding", "d": ["The sliding movement of actin thin filaments and myosin thick filaments past each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051956", "l": "negative regulation of amino acid transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048852", "l": "diencephalon morphogenesis", "d": ["The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050985", "l": "peptidyl-threonine sulfation", "d": ["The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120236", "l": "negative regulation of post-translational protein targeting to membrane, translocation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019856", "l": "pyrimidine nucleobase biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060283", "l": "negative regulation of oocyte development", "d": ["Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086073", "l": "bundle of His cell-Purkinje myocyte adhesion involved in cell communication", "d": ["The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902542", "l": "regulation of protein localization to mitotic spindle pole body", "d": ["Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019528", "l": "D-arabitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019836", "l": "hemolysis by symbiont of host erythrocytes", "d": ["The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033083", "l": "regulation of immature T cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of immature T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051967", "l": "negative regulation of synaptic transmission, glutamatergic", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902799", "l": "regulation of phosphodiesterase I activity", "d": ["Any process that modulates the frequency, rate or extent of phosphodiesterase I activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051166", "l": "2,5-dihydroxypyridine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0060351", "l": "cartilage development involved in endochondral bone morphogenesis", "d": ["The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0002708", "l": "positive regulation of lymphocyte mediated immunity", "d": ["Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0045823", "l": "positive regulation of heart contraction", "d": ["Any process that activates or increases the frequency, rate or extent of heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019344", "l": "cysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120277", "l": "positive regulation of cerebral blood circulation", "d": ["Any process that activates or increases the frequency, rate or extent of cerebral blood circulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902075", "l": "cellular response to salt", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905527", "l": "negative regulation of Golgi lumen acidification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097307", "l": "response to farnesol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033591", "l": "response to L-ascorbic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905389", "l": "response to leukotriene B4", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0043936", "l": "asexual sporulation resulting in formation of a cellular spore", "d": ["The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051757", "l": "meiotic sister chromatid separation", "d": ["The process in which sister chromatids are physically detached from each other during meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904887", "l": "Wnt signalosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.594400196502249", "identifiers": [{"i": "GO:0051648", "l": "vesicle localization", "d": ["Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000659", "l": "regulation of interleukin-1-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900977", "l": "regulation of tatiopterin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tatiopterin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090191", "l": "negative regulation of branching involved in ureteric bud morphogenesis", "d": ["Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045540", "l": "regulation of cholesterol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0050773", "l": "regulation of dendrite development", "d": ["Any process that modulates the frequency, rate or extent of dendrite development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015726", "l": "L-idonate transmembrane transport", "d": ["The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010776", "l": "meiotic mismatch repair involved in meiotic gene conversion", "d": ["A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002912", "l": "negative regulation of lymphocyte anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090114", "l": "COPII-coated vesicle budding", "d": ["The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0007623", "l": "circadian rhythm", "d": ["Any biological process in an organism that recurs with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032898", "l": "neurotrophin production", "d": ["The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002289", "l": "NK T cell proliferation involved in immune response", "d": ["The expansion of a NK T cell population by cell division as part of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010021", "l": "amylopectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904790", "l": "regulation of shelterin complex assembly", "d": ["Any process that modulates the frequency, rate or extent of shelterin complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071590", "l": "nicotinamide riboside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905694", "l": "negative regulation of phosphatidic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000020", "l": "positive regulation of male gonad development", "d": ["Any process that activates or increases the frequency, rate or extent of male gonad development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035695", "l": "mitophagy by induced vacuole formation", "d": ["The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043620", "l": "regulation of DNA-templated transcription in response to stress", "d": ["Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046187", "l": "acetaldehyde catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046140", "l": "corrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001827", "l": "inner cell mass cell fate commitment", "d": ["The cell fate commitment of precursor cells that will become inner cell mass cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902491", "l": "negative regulation of sperm capacitation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019386", "l": "methanogenesis, from carbon dioxide", "d": ["The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901076", "l": "positive regulation of engulfment of apoptotic cell", "d": ["Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050435", "l": "amyloid-beta metabolic process", "d": ["The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904181", "l": "positive regulation of membrane depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044521", "l": "envenomation resulting in muscle damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902566", "l": "regulation of eosinophil activation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015848", "l": "spermidine transport", "d": ["The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900815", "l": "monodictyphenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monodictyphenone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046357", "l": "galactarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0034305", "l": "regulation of asexual sporulation", "d": ["Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "37.034465975199204", "identifiers": [{"i": "GO:0002009", "l": "morphogenesis of an epithelium", "d": ["The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0043129", "l": "surfactant homeostasis", "d": ["Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0033037", "l": "polysaccharide localization", "d": ["Any process in which a polysaccharide is transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0048466", "l": "androecium development", "d": ["The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002946", "l": "tRNA C5-cytosine methylation", "d": ["The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006060", "l": "sorbitol metabolic process", "d": ["The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. 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They are differentiated from flavonoids by the point of attachment of the aromatic ring group."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006047", "l": "UDP-N-acetylglucosamine metabolic process", "d": ["The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046412", "l": "phenylmercury acetate metabolic process", "d": ["The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019540", "l": "catechol-containing siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+)."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903054", "l": "negative regulation of extracellular matrix organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001158", "l": "positive regulation of proline catabolic process to glutamate", "d": ["Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018946", "l": "aerobic organosilicon metabolic process", "d": ["The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051570", "l": "regulation of histone H3-K9 methylation", "d": ["Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900609", "l": "F-9775A metabolic process", "d": ["The chemical reactions and pathways involving F-9775A."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990441", "l": "negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021895", "l": "cerebral cortex neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006634", "l": "hexadecanal biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097222", "l": "mitochondrial mRNA polyadenylation", "d": ["The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000097", "l": "regulation of smooth muscle cell-matrix adhesion", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003411", "l": "cell motility involved in camera-type eye morphogenesis", "d": ["Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900330", "l": "regulation of methane biosynthetic process from trimethylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014726", "l": "negative regulation of extraocular skeletal muscle development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006556", "l": "S-adenosylmethionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.133163844066523", "identifiers": [{"i": "GO:0080090", "l": "regulation of primary metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002558", "l": "type I hypersensitivity mediated by mast cells", "d": ["An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0098762", "l": "meiotic cell cycle phase", "d": ["One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033183", "l": "negative regulation of histone ubiquitination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061789", "l": "dense core granule priming", "d": ["A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051592", "l": "response to calcium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901156", "l": "neomycin metabolic process", "d": ["The chemical reactions and pathways involving neomycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.83295242545627", "identifiers": [{"i": "GO:0022604", "l": "regulation of cell morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0090529", "l": "cell septum assembly", "d": ["The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0045913", "l": "positive regulation of carbohydrate metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044509", "l": "envenomation resulting in modulation of signal transduction in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000443", "l": "regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071463", "l": "cellular response to humidity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048288", "l": "nuclear membrane fusion involved in karyogamy", "d": ["The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061044", "l": "negative regulation of vascular wound healing", "d": ["Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033361", "l": "lysine biosynthetic process via diaminopimelate, dehydrogenase pathway", "d": ["The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061322", "l": "disseminated nephrocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0001990", "l": "regulation of systemic arterial blood pressure by hormone", "d": ["The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006513", "l": "protein monoubiquitination", "d": ["Addition of a single ubiquitin group to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060722", "l": "cell proliferation involved in embryonic placenta development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071543", "l": "diphosphoinositol polyphosphate metabolic process", "d": ["The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.326006727536154", "identifiers": [{"i": "GO:0080134", "l": "regulation of response to stress", "d": ["Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:1905393", "l": "plant organ formation", "d": ["The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003421", "l": "growth plate cartilage axis specification", "d": ["The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045709", "l": "negative regulation of adult salivary gland boundary specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021738", "l": "fastigial nucleus development", "d": ["The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0021966", "l": "corticospinal neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0061326", "l": "renal tubule development", "d": ["The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051305", "l": "chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099076", "l": "mitochondrion to peroxisome transport", "d": ["Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052022", "l": "modulation by symbiont of jasmonic acid levels in host", "d": ["The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009147", "l": "pyrimidine nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0000090", "l": "mitotic anaphase", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000388", "l": "positive regulation of antral ovarian follicle growth", "d": ["Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031150", "l": "sorocarp stalk development", "d": ["The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052652", "l": "cyclic purine nucleotide metabolic process", "d": ["The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140024", "l": "plus-end-directed endosome transport along mitotic spindle midzone microtubule", "d": ["The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902161", "l": "positive regulation of cyclic nucleotide-gated ion channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046170", "l": "methanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0019290", "l": "siderophore biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900247", "l": "regulation of cytoplasmic translational elongation", "d": ["Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021559", "l": "trigeminal nerve development", "d": ["The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1903437", "l": "negative regulation of mitotic cytokinetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903641", "l": "positive regulation of gastrin-induced gastric acid secretion", "d": ["Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0051761", "l": "sesquiterpene metabolic process", "d": ["The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0090287", "l": "regulation of cellular response to growth factor stimulus", "d": ["Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009837", "l": "fruit ripening, non-climacteric", "d": ["A fruit ripening process that does not involve a respiratory burst."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090053", "l": "positive regulation of pericentric heterochromatin formation", "d": ["Any process that increases the frequency, rate or extent of pericentric heterochromatin formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905870", "l": "positive regulation of 3'-UTR-mediated mRNA stabilization", "d": ["Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009938", "l": "negative regulation of gibberellic acid mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014012", "l": "peripheral nervous system axon regeneration", "d": ["The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044862", "l": "protein transport out of plasma membrane raft", "d": ["The directed movement of a protein out of a plasma membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010772", "l": "meiotic DNA recombinase assembly involved in reciprocal meiotic recombination", "d": ["The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050838", "l": "peptidyl-5-hydroxy-L-lysine trimethylation", "d": ["The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901751", "l": "leukotriene A4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene A4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032758", "l": "positive regulation of interleukin-9 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-9 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035482", "l": "gastric motility", "d": ["The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0072163", "l": "mesonephric epithelium development", "d": ["The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019351", "l": "dethiobiotin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006716", "l": "juvenile hormone metabolic process", "d": ["The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.724016924947783", "identifiers": [{"i": "GO:0000278", "l": "mitotic cell cycle", "d": ["Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902070", "l": "positive regulation of sphingolipid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of sphingolipid signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099075", "l": "mitochondrion-derived vesicle mediated transport", "d": ["Transport from the mitochondrion, mediated by mitochondrion derived vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009693", "l": "ethylene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.976534571409303", "identifiers": [{"i": "GO:0065009", "l": "regulation of molecular function", "d": ["Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0140454", "l": "protein aggregate center assembly", "d": ["The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051987", "l": "positive regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902990", "l": "mitotic telomere maintenance via semi-conservative replication", "d": ["Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019417", "l": "sulfur oxidation", "d": ["The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060339", "l": "negative regulation of type I interferon-mediated signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039667", "l": "viral entry into host cell via pilus retraction", "d": ["The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1904555", "l": "L-proline transmembrane transport", "d": ["The directed movement of L-proline across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075197", "l": "haustorium neck formation", "d": ["The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032741", "l": "positive regulation of interleukin-18 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-18 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098886", "l": "modification of dendritic spine", "d": ["Any process that modifies the structure of a dendritic spine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052648", "l": "ribitol phosphate metabolic process", "d": ["The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904438", "l": "regulation of iron ion import across plasma membrane", "d": ["Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904026", "l": "regulation of collagen fibril organization", "d": ["Any process that modulates the frequency, rate or extent of collagen fibril organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036309", "l": "protein localization to M-band", "d": ["Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0098810", "l": "neurotransmitter reuptake", "d": ["The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050691", "l": "regulation of defense response to virus by host", "d": ["Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904961", "l": "quiescent center organization", "d": ["The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001869", "l": "negative regulation of complement activation, lectin pathway", "d": ["Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000004", "l": "regulation of metanephric S-shaped body morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048164", "l": "distinct antral spaces stage", "d": ["The stage in oogenesis when the antral spaces become distinct and the first polar body forms."]}]} {"type": "biolink:BiologicalProcess", "ic": "30.672504607751492", "identifiers": [{"i": "GO:0009791", "l": "post-embryonic development", "d": ["The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0036465", "l": "synaptic vesicle recycling", "d": ["The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902950", "l": "regulation of dendritic spine maintenance", "d": ["Any process that modulates the frequency, rate or extent of dendritic spine maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000606", "l": "regulation of cell proliferation involved in mesonephros development", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014727", "l": "positive regulation of extraocular skeletal muscle development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900260", "l": "negative regulation of RNA-dependent RNA polymerase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055014", "l": "atrial cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070989", "l": "oxidative demethylation", "d": ["The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120062", "l": "positive regulation of gastric emptying", "d": ["Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0051326", "l": "telophase", "d": ["The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009752", "l": "detection of salicylic acid stimulus", "d": ["The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043040", "l": "tRNA aminoacylation for nonribosomal peptide biosynthetic process", "d": ["The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061378", "l": "corpora quadrigemina development", "d": ["The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.25778018697109", "identifiers": [{"i": "GO:0045892", "l": "negative regulation of DNA-templated transcription", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099592", "l": "endocytosed synaptic vesicle processing via endosome", "d": ["The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072130", "l": "renal capsule specification", "d": ["The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048683", "l": "regulation of collateral sprouting of intact axon in response to injury", "d": ["Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000474", "l": "regulation of opioid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901884", "l": "4-hydroxycoumarin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030841", "l": "positive regulation of intermediate filament polymerization", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075246", "l": "negative regulation of oospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140361", "l": "cyclic-GMP-AMP transmembrane import across plasma membrane", "d": ["The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051328", "l": "meiotic interphase", "d": ["The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903626", "l": "positive regulation of DNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of DNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060066", "l": "oviduct development", "d": ["The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900966", "l": "negative regulation of methanophenazine metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010739", "l": "positive regulation of protein kinase A signaling", "d": ["Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045914", "l": "negative regulation of catecholamine metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:1903464", "l": "negative regulation of mitotic cell cycle DNA replication", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045460", "l": "sterigmatocystin metabolic process", "d": ["The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060867", "l": "fruit abscission", "d": ["The controlled shedding of a fruit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075199", "l": "positive regulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035611", "l": "protein branching point deglutamylation", "d": ["The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033027", "l": "positive regulation of mast cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903176", "l": "regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034337", "l": "RNA folding", "d": ["The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070921", "l": "regulation of siRNA processing", "d": ["Any process that modulates the frequency, rate or extent of siRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021685", "l": "cerebellar granular layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905650", "l": "positive regulation of shell calcification", "d": ["Any process that activates or increases the frequency, rate or extent of shell calcification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990544", "l": "mitochondrial ATP transmembrane transport", "d": ["The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045999", "l": "negative regulation of ecdysteroid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003088", "l": "positive regulation of the force of heart contraction by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990359", "l": "stress response to zinc ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000854", "l": "positive regulation of corticosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of corticosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097080", "l": "plasma membrane selenite transport", "d": ["The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060295", "l": "regulation of cilium movement involved in cell motility", "d": ["Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000070", "l": "regulation of response to water deprivation", "d": ["Any process that modulates the frequency, rate or extent of response to water deprivation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900104", "l": "regulation of hyaluranon cable assembly", "d": ["Any process that modulates the frequency, rate or extent of hyaluranon cable assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.898660913853604", "identifiers": [{"i": "GO:0040008", "l": "regulation of growth", "d": ["Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042727", "l": "flavin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031152", "l": "aggregation involved in sorocarp development", "d": ["The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046945", "l": "N-terminal peptidyl-alanine N-carbamoylation", "d": ["The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904764", "l": "chaperone-mediated autophagy translocation complex disassembly", "d": ["The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019084", "l": "middle viral transcription", "d": ["The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097437", "l": "maintenance of dormancy", "d": ["The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046784", "l": "viral mRNA export from host cell nucleus", "d": ["The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904603", "l": "regulation of advanced glycation end-product receptor activity", "d": ["Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904390", "l": "cone retinal bipolar cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044554", "l": "modulation of heart rate in another organism", "d": ["Any process that modulates the frequency or rate of heart contraction of another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060309", "l": "elastin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000384", "l": "negative regulation of ectoderm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046046", "l": "TTP metabolic process", "d": ["The chemical reactions and pathways involving TTP, ribosylthymine triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0015768", "l": "maltose transport", "d": ["The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097494", "l": "regulation of vesicle size", "d": ["Any process that modulates the size of a vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003352", "l": "regulation of cilium movement", "d": ["Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902167", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048577", "l": "negative regulation of short-day photoperiodism, flowering", "d": ["Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902781", "l": "cellular response to nonane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031086", "l": "nuclear-transcribed mRNA catabolic process, deadenylation-independent decay", "d": ["A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075320", "l": "negative regulation of ascus development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.517713470395833", "identifiers": [{"i": "GO:0048066", "l": "developmental pigmentation", "d": ["The developmental process that results in the deposition of coloring matter in an organism, tissue or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901224", "l": "positive regulation of non-canonical NF-kappaB signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045698", "l": "negative regulation of synergid differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000909", "l": "regulation of sterol import", "d": ["Any process that modulates the frequency, rate or extent of sterol import."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033471", "l": "GDP-L-galactose metabolic process", "d": ["The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075273", "l": "positive regulation of zygosporangium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018220", "l": "peptidyl-threonine palmitoylation", "d": ["The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031585", "l": "regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002680", "l": "pro-T cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000961", "l": "negative regulation of cellooligosaccharide metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0010383", "l": "cell wall polysaccharide metabolic process", "d": ["The chemical reactions and pathways involving cell wall polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905352", "l": "ciliary necklace assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033859", "l": "furaldehyde metabolic process", "d": ["The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140245", "l": "regulation of translation at postsynapse", "d": ["Any process that regulates translation occurring at the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046082", "l": "5-methylcytosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045795", "l": "positive regulation of cell volume", "d": ["Any process that increases cell volume."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990893", "l": "mitotic chromosome centromere condensation", "d": ["The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0006511", "l": "ubiquitin-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002421", "l": "B cell antigen processing and presentation following pinocytosis", "d": ["B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050654", "l": "chondroitin sulfate proteoglycan metabolic process", "d": ["The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905519", "l": "negative regulation of presynaptic active zone assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061932", "l": "negative regulation of erythrocyte enucleation", "d": ["Any process that decreases the frequency, rate or extent of erythrocyte enucleation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032776", "l": "DNA methylation on cytosine", "d": ["The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070247", "l": "regulation of natural killer cell apoptotic process", "d": ["Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.989777303936307", "identifiers": [{"i": "GO:0002699", "l": "positive regulation of immune effector process", "d": ["Any process that activates or increases the frequency, rate, or extent of an immune effector process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0008050", "l": "female courtship behavior", "d": ["The behavior of a female, for the purpose of attracting a sexual partner."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061795", "l": "Golgi lumen acidification", "d": ["Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010796", "l": "regulation of multivesicular body size", "d": ["Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0038083", "l": "peptidyl-tyrosine autophosphorylation", "d": ["The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0018277", "l": "protein deamination", "d": ["The removal of an amino group from a protein amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0052170", "l": "suppression of host innate immune response", "d": ["Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0110051", "l": "metabolite repair", "d": ["A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007290", "l": "spermatid nucleus elongation", "d": ["The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019393", "l": "glucarate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0034767", "l": "positive regulation of monoatomic ion transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0039008", "l": "pronephric nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045805", "l": "positive regulation of eclosion", "d": ["Any process that activates or increases the frequency, rate or extent of eclosion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902551", "l": "regulation of catalase activity", "d": ["Any process that modulates the frequency, rate or extent of catalase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046709", "l": "IDP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003193", "l": "pulmonary valve formation", "d": ["The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035977", "l": "protein deglycosylation involved in glycoprotein catabolic process", "d": ["The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032689", "l": "negative regulation of type II interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051343", "l": "positive regulation of cyclic-nucleotide phosphodiesterase activity", "d": ["Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042865", "l": "pyochelin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0009111", "l": "vitamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903854", "l": "negative regulation of stress response to copper ion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048673", "l": "collateral sprouting of intact axon in response to injury", "d": ["The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110120", "l": "gamma-tubulin complex localization to nuclear side of mitotic spindle pole body", "d": ["Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033123", "l": "positive regulation of purine nucleotide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042247", "l": "establishment of planar polarity of follicular epithelium", "d": ["Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015937", "l": "coenzyme A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043481", "l": "anthocyanin accumulation in tissues in response to UV light", "d": ["The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0014016", "l": "neuroblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. 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The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0036490", "l": "regulation of translation in response to endoplasmic reticulum stress", "d": ["Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0030010", "l": "establishment of cell polarity", "d": ["The specification and formation of anisotropic intracellular organization or cell growth patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903366", "l": "negative regulation of fear response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fear response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010145", "l": "fructan metabolic process", "d": ["The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072745", "l": "cellular response to antimycin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905696", "l": "regulation of polysome binding", "d": ["Any process that modulates the frequency, rate or extent of polysome binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0017198", "l": "N-terminal peptidyl-serine acetylation", "d": ["The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072155", "l": "epithelial cell migration involved in nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904289", "l": "regulation of mitotic DNA damage checkpoint", "d": ["Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.597130837682087", "identifiers": [{"i": "GO:0023056", "l": "positive regulation of signaling", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of a signaling process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000137", "l": "negative regulation of cell proliferation involved in heart morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010689", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0052160", "l": "perturbation of host systemic acquired resistance", "d": ["A process in which an organism effects a change that affects systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044874", "l": "lipoprotein localization to outer membrane", "d": ["A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045037", "l": "protein import into chloroplast stroma", "d": ["The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032286", "l": "central nervous system myelin maintenance", "d": ["The process in which the structure and material content of mature central nervous system myelin is kept in a functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0030901", "l": "midbrain development", "d": ["The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900069", "l": "regulation of cellular hyperosmotic salinity response", "d": ["Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905521", "l": "regulation of macrophage migration", "d": ["Any process that modulates the frequency, rate or extent of macrophage migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903238", "l": "positive regulation of leukocyte tethering or rolling", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900508", "l": "positive regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901625", "l": "cellular response to ergosterol", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0062149", "l": "detection of stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903667", "l": "regulation of chemorepellent activity", "d": ["Any process that modulates the frequency, rate or extent of chemorepellent activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032100", "l": "positive regulation of appetite", "d": ["Any process that increases appetite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061457", "l": "mesonephric cell migration involved in male gonad development", "d": ["The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.702982456578013", "identifiers": [{"i": "GO:0051338", "l": "regulation of transferase activity", "d": ["Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051043", "l": "regulation of membrane protein ectodomain proteolysis", "d": ["Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060542", "l": "regulation of strand invasion", "d": ["Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900985", "l": "vindoline biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of vindoline."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902218", "l": "regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "d": ["Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904580", "l": "regulation of intracellular mRNA localization", "d": ["Any process that modulates the frequency, rate or extent of intracellular mRNA localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042711", "l": "maternal behavior", "d": ["Female behaviors associated with the care and rearing of offspring."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098941", "l": "anterograde trans-synaptic signaling by trans-synaptic protein complex", "d": ["Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.204937007788899", "identifiers": [{"i": "GO:0001963", "l": "synaptic transmission, dopaminergic", "d": ["The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110044", "l": "regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990976", "l": "protein transport along microtubule to mitotic spindle pole body", "d": ["The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045696", "l": "positive regulation of embryo sac egg cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902801", "l": "regulation of siRNA-independent facultative heterochromatin formation", "d": ["Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010234", "l": "anther wall tapetum cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002454", "l": "peripheral B cell deletion", "d": ["The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019288", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042418", "l": "epinephrine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0010498", "l": "proteasomal protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0006638", "l": "neutral lipid metabolic process", "d": ["The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099049", "l": "clathrin coat assembly involved in endocytosis", "d": ["The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018364", "l": "peptidyl-glutamine methylation", "d": ["The addition of a methyl group to a glutamine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061567", "l": "dCMP phosphorylation", "d": ["The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090168", "l": "Golgi reassembly", "d": ["The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010066", "l": "ground meristem histogenesis", "d": ["The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903451", "l": "negative regulation of G1 to G0 transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032948", "l": "regulation of alpha-glucan metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106016", "l": "positive regulation of inflammatory response to wounding", "d": ["Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902665", "l": "response to isobutanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0007194", "l": "negative regulation of adenylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002551", "l": "mast cell chemotaxis", "d": ["The movement of a mast cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033381", "l": "establishment of granzyme B localization to T cell secretory granule", "d": ["The directed movement of the protease granzyme B to a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071948", "l": "activation-induced B cell apoptotic process", "d": ["B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009560", "l": "embryo sac egg cell differentiation", "d": ["The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051467", "l": "detection of steroid hormone stimulus", "d": ["The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1902305", "l": "regulation of sodium ion transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021647", "l": "vestibulocochlear nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010891", "l": "negative regulation of sequestering of triglyceride", "d": ["Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046666", "l": "retinal cell programmed cell death", "d": ["Programmed cell death that occurs in the developing retina."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070384", "l": "Harderian gland development", "d": ["The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060234", "l": "neuroblast delamination", "d": ["The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032889", "l": "regulation of vacuole fusion, non-autophagic", "d": ["Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070276", "l": "halogen metabolic process", "d": ["The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019593", "l": "mannitol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071282", "l": "cellular response to iron(II) ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071947", "l": "protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "d": ["The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097022", "l": "lymphocyte migration into lymph node", "d": ["The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903343", "l": "positive regulation of meiotic DNA double-strand break formation", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903882", "l": "negative regulation of interleukin-17-mediated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097577", "l": "sequestering of iron ion", "d": ["The process of binding or confining iron ions such that they are separated from other components of a biological system."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018983", "l": "Z-phenylacetaldoxime metabolic process", "d": ["The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036305", "l": "ameloblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032086", "l": "regulation of type III site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0006749", "l": "glutathione metabolic process", "d": ["The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990216", "l": "positive regulation by symbiont of host transcription", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904039", "l": "negative regulation of iron export across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903473", "l": "positive regulation of mitotic actomyosin contractile ring contraction", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902800", "l": "positive regulation of phosphodiesterase I activity", "d": ["Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003372", "l": "establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010722", "l": "regulation of ferrochelatase activity", "d": ["Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:1901889", "l": "negative regulation of cell junction assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990546", "l": "mitochondrial tricarboxylic acid transmembrane transport", "d": ["The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0007306", "l": "egg chorion assembly", "d": ["Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018005", "l": "N-terminal peptidyl-glycine N-formylation", "d": ["The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003298", "l": "physiological muscle hypertrophy", "d": ["The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140113", "l": "extracellular microvesicle biogenesis", "d": ["The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097252", "l": "oligodendrocyte apoptotic process", "d": ["Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033475", "l": "indoleacetic acid amide conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071041", "l": "antisense RNA transcript catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904591", "l": "positive regulation of protein import", "d": ["Any process that activates or increases the frequency, rate or extent of protein import."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060323", "l": "head morphogenesis", "d": ["The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990440", "l": "positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "d": ["Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902463", "l": "protein localization to cell leading edge", "d": ["A process in which a protein is transported to, or maintained in, a location within a cell leading edge."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900615", "l": "emericellamide A metabolic process", "d": ["The chemical reactions and pathways involving emericellamide A."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001748", "l": "insect visual primordium development", "d": ["The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044331", "l": "cell-cell adhesion mediated by cadherin", "d": ["The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900965", "l": "regulation of methanophenazine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of methanophenazine metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072633", "l": "interleukin-30 production", "d": ["The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042849", "l": "L-sorbose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019370", "l": "leukotriene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003066", "l": "positive regulation of heart rate by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046158", "l": "ocellus pigment metabolic process", "d": ["The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061388", "l": "regulation of rate of cell growth", "d": ["Any process that modulates the rate of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000390", "l": "spliceosomal complex disassembly", "d": ["Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000821", "l": "regulation of grooming behavior", "d": ["Any process that modulates the frequency, rate or extent of grooming behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075003", "l": "adhesion of symbiont appressorium to host", "d": ["The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042323", "l": "negative regulation of circadian sleep/wake cycle, non-REM sleep", "d": ["Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0060443", "l": "mammary gland morphogenesis", "d": ["The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007116", "l": "regulation of cell budding", "d": ["Any process that modulates the frequency, rate or extent of the formation and growth of cell buds."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010416", "l": "arabinoxylan-containing compound metabolic process", "d": ["The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0018942", "l": "organometal metabolic process", "d": ["The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0097354", "l": "prenylation", "d": ["The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072298", "l": "regulation of metanephric glomerulus development", "d": ["Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0003093", "l": "regulation of glomerular filtration", "d": ["Any process that modulates the frequency, rate or extent of glomerular filtration. 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During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048919", "l": "posterior lateral line neuromast development", "d": ["The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903004", "l": "regulation of protein K63-linked deubiquitination", "d": ["Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010784", "l": "proboscis morphogenesis, clypeo-labral disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990551", "l": "mitochondrial 2-oxoadipate transmembrane transport", "d": ["The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0097164", "l": "ammonium ion metabolic process", "d": ["The chemical reactions and pathways involving the ammonium ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035818", "l": "positive regulation of urine volume by pressure natriuresis", "d": ["An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0044557", "l": "relaxation of smooth muscle", "d": ["A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905835", "l": "cellular response to pyrimidine ribonucleotide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032149", "l": "response to rhamnose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052778", "l": "diacetylchitobiose metabolic process", "d": ["The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1900239", "l": "regulation of phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046161", "l": "heme a catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060497", "l": "mesenchymal-endodermal cell signaling", "d": ["Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0019233", "l": "sensory perception of pain", "d": ["The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042354", "l": "L-fucose metabolic process", "d": ["The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0035834", "l": "indole alkaloid metabolic process", "d": ["The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051892", "l": "negative regulation of cardioblast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901945", "l": "miltiradiene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of miltiradiene."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.198535815504115", "identifiers": [{"i": "GO:0045787", "l": "positive regulation of cell cycle", "d": ["Any process that activates or increases the rate or extent of progression through the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.181576135344244", "identifiers": [{"i": "GO:1902105", "l": "regulation of leukocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of leukocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0033484", "l": "intracellular nitric oxide homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106117", "l": "acidocalcisome organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0006779", "l": "porphyrin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007394", "l": "dorsal closure, elongation of leading edge cells", "d": ["The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0061028", "l": "establishment of endothelial barrier", "d": ["The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006103", "l": "2-oxoglutarate metabolic process", "d": ["The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904072", "l": "presynaptic active zone disassembly", "d": ["The disaggregation of a presynaptic active zone into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090154", "l": "positive regulation of sphingolipid biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045663", "l": "positive regulation of myoblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0008045", "l": "motor neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0014721", "l": "twitch skeletal muscle contraction", "d": ["A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0036230", "l": "granulocyte activation", "d": ["The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.468812710017168", "identifiers": [{"i": "GO:0007420", "l": "brain development", "d": ["The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0021761", "l": "limbic system development", "d": ["The progression of the limbic system over time from its initial formation until its mature state. 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A metanephric tubule is an epithelial tube that is part of the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.946107901282822", "identifiers": [{"i": "GO:0009968", "l": "negative regulation of signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904282", "l": "regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.212823685559968", "identifiers": [{"i": "GO:0016310", "l": "phosphorylation", "d": ["The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0060041", "l": "retina development in camera-type eye", "d": ["The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:1902100", "l": "negative regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032782", "l": "bile acid secretion", "d": ["The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032955", "l": "regulation of division septum assembly", "d": ["Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033306", "l": "phytol metabolic process", "d": ["The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072260", "l": "metanephric interstitial fibroblast fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000704", "l": "positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.133821031307569", "identifiers": [{"i": "GO:0010557", "l": "positive regulation of macromolecule biosynthetic process", "d": ["Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050812", "l": "regulation of acyl-CoA biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903498", "l": "bundle sheath cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000130", "l": "positive regulation of octopamine signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000568", "l": "positive regulation of memory T cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of memory T cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048380", "l": "negative regulation of lateral mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903236", "l": "regulation of leukocyte tethering or rolling", "d": ["Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071350", "l": "cellular response to interleukin-15", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.820827815612489", "identifiers": [{"i": "GO:0048732", "l": "gland development", "d": ["The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032912", "l": "negative regulation of transforming growth factor beta2 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902549", "l": "protein localization to Mei2 nuclear dot", "d": ["A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905813", "l": "negative regulation of motor neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010877", "l": "lipid transport involved in lipid storage", "d": ["The directed movement of lipids into cells that is part of their accumulation and maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061452", "l": "retrotrapezoid nucleus neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021582", "l": "medulla oblongata maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900971", "l": "regulation of sarcinapterin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097089", "l": "methyl-branched fatty acid metabolic process", "d": ["The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060893", "l": "limb granular cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051634", "l": "inhibition of acetylcholine uptake", "d": ["Any process that prevents the activation of the directed movement of acetylcholine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904554", "l": "positive regulation of chemotaxis to arachidonic acid", "d": ["Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.528458322397171", "identifiers": [{"i": "GO:0015031", "l": "protein transport", "d": ["The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072149", "l": "podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001769", "l": "establishment of B cell polarity", "d": ["The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140421", "l": "endocytic heme import into cell", "d": ["The directed movement into cell of externally available heme by receptor-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006463", "l": "steroid hormone receptor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:2000725", "l": "regulation of cardiac muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051382", "l": "kinetochore assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021682", "l": "nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010030", "l": "positive regulation of seed germination", "d": ["Any process that activates or increase the rate of seed germination."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0030193", "l": "regulation of blood coagulation", "d": ["Any process that modulates the frequency, rate or extent of blood coagulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035002", "l": "liquid clearance, open tracheal system", "d": ["The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002351", "l": "serotonin production involved in inflammatory response", "d": ["The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019487", "l": "anaerobic acetylene catabolic process", "d": ["The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060705", "l": "neuron differentiation involved in salivary gland development", "d": ["The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032672", "l": "regulation of interleukin-3 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-3 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007299", "l": "follicle cell of egg chamber-cell adhesion", "d": ["The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061707", "l": "extracellular exosome macropinocytosis", "d": ["The single-organism macropinocytosis process that results in the uptake of an extracellular exosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048695", "l": "negative regulation of collateral sprouting of injured axon", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000123", "l": "positive regulation of stomatal complex development", "d": ["Any process that activates or increases the frequency, rate or extent of stomatal complex development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018404", "l": "protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099556", "l": "trans-synaptic signaling by carbon monoxide, modulating synaptic transmission", "d": ["Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009912", "l": "auditory receptor cell fate commitment", "d": ["The process in which the cellular identity of auditory hair cells is acquired and determined."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0075294", "l": "positive regulation by symbiont of entry into host", "d": ["Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.999780418226806", "identifiers": [{"i": "GO:0007620", "l": "copulation", "d": ["The act of sexual union between male and female, involving the transfer of sperm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072307", "l": "regulation of metanephric nephron tubule epithelial cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903278", "l": "positive regulation of sodium ion export across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099593", "l": "endocytosed synaptic vesicle to endosome fusion", "d": ["Fusion of an endocytosed synaptic vesicle with an endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110038", "l": "negative regulation of nematode male tail tip morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0070791", "l": "cleistothecium development", "d": ["The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006268", "l": "DNA unwinding involved in DNA replication", "d": ["The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039023", "l": "pronephric duct morphogenesis", "d": ["The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015690", "l": "aluminum cation transport", "d": ["The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904912", "l": "positive regulation of establishment of RNA localization to telomere", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002157", "l": "positive regulation of thyroid hormone mediated signaling pathway", "d": ["Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034970", "l": "histone H3-R2 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031392", "l": "regulation of prostaglandin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900863", "l": "positive regulation of cordyol C biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0040022", "l": "feminization of hermaphroditic germ-line", "d": ["The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903011", "l": "negative regulation of bone development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone development."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0009218", "l": "pyrimidine ribonucleotide metabolic process", "d": ["The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051891", "l": "positive regulation of cardioblast differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903187", "l": "negative regulation of vitellogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060789", "l": "hair follicle placode formation", "d": ["The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000382", "l": "positive regulation of mesoderm development", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048631", "l": "regulation of skeletal muscle tissue growth", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009951", "l": "polarity specification of dorsal/ventral axis", "d": ["Any process resulting in the establishment of polarity along the dorsal/ventral axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000717", "l": "positive regulation of maintenance of mitotic sister chromatid cohesion, arms", "d": ["Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.88020023694385", "identifiers": [{"i": "GO:0035710", "l": "CD4-positive, alpha-beta T cell activation", "d": ["The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015860", "l": "purine nucleoside transmembrane transport", "d": ["The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903386", "l": "negative regulation of homophilic cell adhesion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0120109", "l": "mitotic telomere clustering and tethering at nuclear periphery", "d": ["The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009853", "l": "photorespiration", "d": ["A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046807", "l": "viral scaffold assembly and maintenance", "d": ["The assembly and maintenance of the viral scaffold around which the viral capsid is constructed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900587", "l": "arugosin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arugosin."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0035932", "l": "aldosterone secretion", "d": ["The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0055011", "l": "atrial cardiac muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905323", "l": "telomerase holoenzyme complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905711", "l": "response to phosphatidylethanolamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010973", "l": "positive regulation of division septum assembly", "d": ["Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1903778", "l": "protein localization to vacuolar membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072118", "l": "pronephros structural organization", "d": ["The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097115", "l": "neurexin clustering involved in presynaptic membrane assembly", "d": ["The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019457", "l": "methionine catabolic process to succinyl-CoA", "d": ["The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033385", "l": "geranylgeranyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1990089", "l": "response to nerve growth factor", "d": ["A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061190", "l": "regulation of sclerotome development", "d": ["Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0060487", "l": "lung epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "42.613586036504465", "identifiers": [{"i": "GO:0008283", "l": "cell population proliferation", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150035", "l": "regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042188", "l": "1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007042", "l": "lysosomal lumen acidification", "d": ["Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900915", "l": "negative regulation of octadecene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902889", "l": "protein localization to spindle microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a spindle microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039513", "l": "suppression by virus of host catalytic activity", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048075", "l": "positive regulation of eye pigmentation", "d": ["Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001125", "l": "negative regulation of translational frameshifting", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070164", "l": "negative regulation of adiponectin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0003171", "l": "atrioventricular valve development", "d": ["The progression of the atrioventricular valve over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000393", "l": "negative regulation of lamellipodium morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902455", "l": "negative regulation of stem cell population maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.887268378082027", "identifiers": [{"i": "GO:0009612", "l": "response to mechanical stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905580", "l": "positive regulation of ERBB3 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904571", "l": "positive regulation of selenocysteine incorporation", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046302", "l": "2-chloro-N-isopropylacetanilide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051351", "l": "positive regulation of ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000859", "l": "negative regulation of aldosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905230", "l": "response to borneol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048160", "l": "primary follicle stage", "d": ["The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.986321514069708", "identifiers": [{"i": "GO:0098813", "l": "nuclear chromosome segregation", "d": ["The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009769", "l": "photosynthesis, light harvesting in photosystem II", "d": ["After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000383", "l": "regulation of ectoderm development", "d": ["Any process that modulates the frequency, rate or extent of ectoderm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020033", "l": "antigenic variation", "d": ["Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018254", "l": "peptidyl-tyrosine adenylylation", "d": ["The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032608", "l": "interferon-beta production", "d": ["The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090249", "l": "regulation of cell migration involved in somitogenic axis elongation", "d": ["Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0002820", "l": "negative regulation of adaptive immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0070597", "l": "cell wall (1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090180", "l": "positive regulation of thiamine biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.989518803060442", "identifiers": [{"i": "GO:0009611", "l": "response to wounding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0072531", "l": "pyrimidine-containing compound transmembrane transport", "d": ["The process in which a pyrimidine-containing compound is transported across a membrane. 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The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051457", "l": "maintenance of protein location in nucleus", "d": ["Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060260", "l": "regulation of transcription initiation by RNA polymerase II", "d": ["Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070398", "l": "wall teichoic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050784", "l": "cocaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090551", "l": "response to manganese starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043469", "l": "regulation of D-xylose catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.51239634443381", "identifiers": [{"i": "GO:0046530", "l": "photoreceptor cell differentiation", "d": ["The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044498", "l": "envenomation resulting in modulation of blood pressure in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0006825", "l": "copper ion transport", "d": ["The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070092", "l": "regulation of glucagon secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of glucagon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905810", "l": "regulation of excitatory synapse pruning", "d": ["Any process that modulates the frequency, rate or extent of excitatory synapse pruning."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032668", "l": "regulation of interleukin-24 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-24 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090701", "l": "specification of plant organ identity", "d": ["The regionalization process in which the identity of a plant organ primordium is specified. 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The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072290", "l": "epithelial cell migration involved in metanephric nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904991", "l": "negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061189", "l": "positive regulation of sclerotome development", "d": ["Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072291", "l": "epithelial cell migration involved in metanephric distal tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0042843", "l": "D-xylose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0097588", "l": "archaeal or bacterial-type flagellum-dependent cell motility", "d": ["Cell motility due to movement of bacterial- or archaeal-type flagella."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0046637", "l": "regulation of alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003048", "l": "regulation of systemic arterial blood pressure by norepinephrine", "d": ["The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060746", "l": "parental behavior", "d": ["A reproductive behavior in which a parent cares for and rears offspring."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043501", "l": "skeletal muscle adaptation", "d": ["Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900698", "l": "regulation of o-orsellinic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070786", "l": "positive regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061252", "l": "mesonephric glomerular epithelial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003049", "l": "regulation of systemic arterial blood pressure by capillary fluid shift", "d": ["The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0043450", "l": "alkene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0044691", "l": "tooth eruption", "d": ["The tooth development process in which the teeth enter the mouth and become visible."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904189", "l": "positive regulation of transformation of host cell by virus", "d": ["Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090009", "l": "primitive streak formation", "d": ["The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009256", "l": "10-formyltetrahydrofolate metabolic process", "d": ["The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061633", "l": "transport-coupled glycolytic process through glucose-6-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990543", "l": "mitochondrial S-adenosyl-L-methionine transmembrane transport", "d": ["The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019293", "l": "tyrosine biosynthetic process, by oxidation of phenylalanine", "d": ["The conversion of phenylalanine to tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003328", "l": "pancreatic D cell fate commitment", "d": ["The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000080", "l": "negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0048793", "l": "pronephros development", "d": ["The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0042455", "l": "ribonucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905210", "l": "regulation of fibroblast chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of fibroblast chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0048892", "l": "lateral line nerve development", "d": ["The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0035019", "l": "somatic stem cell population maintenance", "d": ["Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090386", "l": "phagosome maturation involved in apoptotic cell clearance", "d": ["A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010581", "l": "regulation of starch biosynthetic process", "d": ["An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900540", "l": "fumonisin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fumonisin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000477", "l": "regulation of metanephric podocyte development", "d": ["Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904243", "l": "negative regulation of pancreatic trypsinogen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048643", "l": "positive regulation of skeletal muscle tissue development", "d": ["Any process that activates, maintains or increases the rate of skeletal muscle tissue development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036484", "l": "trunk neural crest cell migration", "d": ["The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0031640", "l": "killing of cells of another organism", "d": ["Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0009453", "l": "energy taxis", "d": ["The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046109", "l": "uridine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:1903747", "l": "regulation of establishment of protein localization to mitochondrion", "d": ["Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0009251", "l": "glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0003279", "l": "cardiac septum development", "d": ["The progression of a cardiac septum over time, from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904251", "l": "regulation of bile acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of bile acid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002596", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044418", "l": "translocation of DNA into host", "d": ["The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035099", "l": "hemocyte migration", "d": ["The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098709", "l": "glutathione import across plasma membrane", "d": ["The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010700", "l": "negative regulation of norepinephrine secretion", "d": ["Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042694", "l": "muscle cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002488", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015954", "l": "pyrimidine ribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904783", "l": "positive regulation of NMDA glutamate receptor activity", "d": ["Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072228", "l": "metanephric prebend segment development", "d": ["The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905628", "l": "negative regulation of serotonin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902432", "l": "protein localization to division septum", "d": ["A process in which a protein is transported to, or maintained in, a location within a division septum."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:1903429", "l": "regulation of cell maturation", "d": ["Any process that modulates the frequency, rate or extent of cell maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000437", "l": "carbon catabolite repression of transcription from RNA polymerase II promoter", "d": ["A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031336", "l": "negative regulation of sulfur amino acid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903998", "l": "regulation of eating behavior", "d": ["Any process that modulates the frequency, rate or extent of eating behavior."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0070166", "l": "enamel mineralization", "d": ["The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034395", "l": "regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900763", "l": "averantin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of averantin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090459", "l": "intracellular aspartate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0090207", "l": "regulation of triglyceride metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900122", "l": "positive regulation of receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048056", "l": "R3/R4 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051862", "l": "translocation of molecules into symbiont", "d": ["The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902842", "l": "negative regulation of netrin-activated signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0031076", "l": "embryonic camera-type eye development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.413077406256658", "identifiers": [{"i": "GO:0071704", "l": "organic substance metabolic process", "d": ["The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006433", "l": "prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904983", "l": "glycine import into mitochondrion", "d": ["The process in which glycine is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070308", "l": "lens fiber cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0010165", "l": "response to X-ray", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050823", "l": "peptide antigen stabilization", "d": ["Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015769", "l": "melibiose transport", "d": ["The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090186", "l": "regulation of pancreatic juice secretion", "d": ["Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002240", "l": "response to molecule of oomycetes origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0062232", "l": "prostanoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prostanoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001732", "l": "formation of cytoplasmic translation initiation complex", "d": ["Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0050729", "l": "positive regulation of inflammatory response", "d": ["Any process that activates or increases the frequency, rate or extent of the inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043468", "l": "regulation of fucose catabolic process", "d": ["Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0070741", "l": "response to interleukin-6", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010616", "l": "negative regulation of cardiac muscle adaptation", "d": ["Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010014", "l": "meristem initiation", "d": ["Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061325", "l": "cell proliferation involved in outflow tract morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904409", "l": "regulation of secretory granule organization", "d": ["Any process that modulates the frequency, rate or extent of secretory granule organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902859", "l": "propionyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of propionyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905237", "l": "response to cyclosporin A", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043451", "l": "alkene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075514", "l": "endosome lysis involved in viral entry into host cell", "d": ["Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902596", "l": "negative regulation of DNA replication origin binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905155", "l": "positive regulation of membrane invagination", "d": ["Any process that activates or increases the frequency, rate or extent of membrane invagination."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018410", "l": "C-terminal protein amino acid modification", "d": ["The alteration of the C-terminal amino acid residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.408607444211199", "identifiers": [{"i": "GO:0032984", "l": "protein-containing complex disassembly", "d": ["The disaggregation of a protein-containing macromolecular complex into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010198", "l": "synergid death", "d": ["Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001575", "l": "globoside metabolic process", "d": ["The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036495", "l": "negative regulation of translation initiation in response to endoplasmic reticulum stress", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071903", "l": "protein N-linked N-acetylglucosaminylation via asparagine", "d": ["A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051110", "l": "peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine", "d": ["The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050771", "l": "negative regulation of axonogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046311", "l": "prenylcysteine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1990956", "l": "fibroblast chemotaxis", "d": ["The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001967", "l": "suckling behavior", "d": ["Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0003030", "l": "detection of hydrogen ion", "d": ["The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000349", "l": "negative regulation of CD40 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009183", "l": "purine deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035310", "l": "notum cell fate specification", "d": ["The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021522", "l": "spinal cord motor neuron differentiation", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901546", "l": "regulation of synaptic vesicle lumen acidification", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0071634", "l": "regulation of transforming growth factor beta production", "d": ["Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021858", "l": "GABAergic neuron differentiation in basal ganglia", "d": ["The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0032638", "l": "interleukin-9 production", "d": ["The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000294", "l": "nuclear-transcribed mRNA catabolic process, RNase MRP-dependent", "d": ["A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046829", "l": "negative regulation of RNA import into nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0007272", "l": "ensheathment of neurons", "d": ["The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1901502", "l": "ether catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ether."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902295", "l": "synthesis of RNA primer involved in cell cycle DNA replication", "d": ["Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903582", "l": "negative regulation of basophil degranulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060701", "l": "negative regulation of ribonuclease activity", "d": ["Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010028", "l": "xanthophyll cycle", "d": ["A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072736", "l": "cellular response to tert-butyl hydroperoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045587", "l": "negative regulation of gamma-delta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "57.627202240952215", "identifiers": [{"i": "GO:0002460", "l": "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015776", "l": "capsular polysaccharide transport", "d": ["The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006659", "l": "phosphatidylserine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060067", "l": "cervix development", "d": ["The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002194", "l": "hepatocyte cell migration", "d": ["The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.154601071495392", "identifiers": [{"i": "GO:0009893", "l": "positive regulation of metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060124", "l": "positive regulation of growth hormone secretion", "d": ["Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035073", "l": "pupariation", "d": ["The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007291", "l": "sperm individualization", "d": ["The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0039654", "l": "fusion of virus membrane with host endosome membrane", "d": ["Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900506", "l": "regulation of iron-sulfur-molybdenum cofactor assembly", "d": ["Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044861", "l": "protein transport into plasma membrane raft", "d": ["The directed movement of a protein into a plasma membrane raft."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0097553", "l": "calcium ion transmembrane import into cytosol", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072651", "l": "interferon-tau production", "d": ["The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036039", "l": "curcumin metabolic process", "d": ["The chemical reactions and pathways involving the polyphenol, curcumin."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:0051702", "l": "biological process involved in interaction with symbiont", "d": ["An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002591", "l": "positive regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071334", "l": "cellular response to rhamnose stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006035", "l": "cuticle chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903285", "l": "positive regulation of hydrogen peroxide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043710", "l": "cell adhesion involved in multi-species biofilm formation", "d": ["The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090649", "l": "response to oxygen-glucose deprivation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0032366", "l": "intracellular sterol transport", "d": ["The directed movement of sterols within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:0001525", "l": "angiogenesis", "d": ["Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061648", "l": "tooth replacement", "d": ["The process whose specific outcome is the replacement of an existing tooth with another tooth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050677", "l": "positive regulation of urothelial cell proliferation", "d": ["Any process that activates or increases the rate or extent of urothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080114", "l": "positive regulation of glycine hydroxymethyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150102", "l": "negative regulation of monocyte activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009934", "l": "regulation of meristem structural organization", "d": ["Any process that modulates the frequency, rate or extent of meristem organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046085", "l": "adenosine metabolic process", "d": ["The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097375", "l": "spinal sensory neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007518", "l": "myoblast fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051667", "l": "establishment of plastid localization", "d": ["The directed movement of a plastid to a specific location in the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051686", "l": "establishment of ER localization", "d": ["The directed movement of the endoplasmic reticulum to a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0141087", "l": "positive regulation of inflammasome-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000807", "l": "regulation of synaptic vesicle clustering", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle clustering."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035908", "l": "ventral aorta development", "d": ["The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0140354", "l": "lipid import into cell", "d": ["The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010419", "l": "rhamnogalacturonan II side chain metabolic process", "d": ["The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032973", "l": "amino acid export across plasma membrane", "d": ["The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0010586", "l": "miRNA metabolic process", "d": ["The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006622", "l": "protein targeting to lysosome", "d": ["The process of directing proteins towards the lysosome using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.433245225553328", "identifiers": [{"i": "GO:0007608", "l": "sensory perception of smell", "d": ["The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000999", "l": "positive regulation of cellulose catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of cellulose catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010837", "l": "regulation of keratinocyte proliferation", "d": ["Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903072", "l": "regulation of death-inducing signaling complex assembly", "d": ["Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061819", "l": "telomeric DNA-containing double minutes formation", "d": ["A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903916", "l": "regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010540", "l": "basipetal auxin transport", "d": ["The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0010894", "l": "negative regulation of steroid biosynthetic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0044630", "l": "modulation of complement activation, lectin pathway in another organism", "d": ["A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043376", "l": "regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0042908", "l": "xenobiotic transport", "d": ["The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042038", "l": "peptidyl-histidine methylation, to form tele-methylhistidine", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045678", "l": "positive regulation of R7 cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of R7 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035134", "l": "post-embryonic dorsal fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044314", "l": "protein K27-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070903", "l": "mitochondrial tRNA thio-modification", "d": ["The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046068", "l": "cGMP metabolic process", "d": ["The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000820", "l": "negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation", "d": ["Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042433", "l": "indole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048359", "l": "mucilage metabolic process involved in seed coat development", "d": ["The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901832", "l": "all-trans-neoxanthin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015783", "l": "GDP-fucose transmembrane transport", "d": ["The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0090132", "l": "epithelium migration", "d": ["The process in which the population of cells that make up an epithelium undergo directed movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900279", "l": "regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006110", "l": "regulation of glycolytic process", "d": ["Any process that modulates the frequency, rate or extent of glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044512", "l": "envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002871", "l": "regulation of natural killer cell tolerance induction", "d": ["Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075315", "l": "positive regulation of basidium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904295", "l": "regulation of osmolarity-sensing cation channel activity", "d": ["Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019878", "l": "lysine biosynthetic process via aminoadipic acid", "d": ["The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901179", "l": "spheroidene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of spheroidene."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032836", "l": "glomerular basement membrane development", "d": ["The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006607", "l": "NLS-bearing protein import into nucleus", "d": ["The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0014023", "l": "neural rod formation", "d": ["The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905454", "l": "negative regulation of myeloid progenitor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002942", "l": "tRNA m2,2-guanine biosynthesis", "d": ["The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.594400196502249", "identifiers": [{"i": "GO:0048820", "l": "hair follicle maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045711", "l": "positive regulation of adult salivary gland boundary specification", "d": ["Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006559", "l": "L-phenylalanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0006279", "l": "premeiotic DNA replication", "d": ["The replication of DNA that precedes meiotic cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044067", "l": "disruption of host cell-cell junction", "d": ["The process by which a symbiont effects a change in the structure or function of an intercellular junction of the host. Intercellular junction include tight junctions and adherens junctions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072748", "l": "cellular response to tacrolimus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902992", "l": "negative regulation of amyloid precursor protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900076", "l": "regulation of cellular response to insulin stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016346", "l": "male meiotic chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046377", "l": "colanic acid metabolic process", "d": ["The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904183", "l": "negative regulation of pyruvate dehydrogenase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902728", "l": "positive regulation of growth factor dependent skeletal muscle satellite cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039652", "l": "induction by virus of host NF-kappaB cascade", "d": ["A process in which a virus initiates, promotes, or enhances a host NF-kappaB signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0140650", "l": "radial glia-guided pyramidal neuron migration", "d": ["The radial migration of a pyramidal neuron along radial glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034302", "l": "akinete formation", "d": ["The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1904809", "l": "regulation of dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903979", "l": "negative regulation of microglial cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901548", "l": "positive regulation of synaptic vesicle lumen acidification", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071370", "l": "cellular response to gibberellin stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903752", "l": "positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060622", "l": "regulation of ascospore wall beta-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060958", "l": "endocardial cell development", "d": ["The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0045230", "l": "capsule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904016", "l": "response to Thyroglobulin triiodothyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001269", "l": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0046541", "l": "saliva secretion", "d": ["The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035705", "l": "T-helper 17 cell chemotaxis", "d": ["The directed movement of a T-helper 17 cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0051340", "l": "regulation of ligase activity", "d": ["Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903926", "l": "cellular response to bisphenol A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0009808", "l": "lignin metabolic process", "d": ["The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051697", "l": "protein delipidation", "d": ["The breakage of covalent bonds to detach lipid groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018418", "l": "nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide", "d": ["The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050844", "l": "peptidyl-selenocysteine modification", "d": ["The modification of peptidyl-selenocysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009554", "l": "megasporogenesis", "d": ["The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009682", "l": "induced systemic resistance", "d": ["A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901467", "l": "negative regulation of ferulate catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002631", "l": "regulation of granuloma formation", "d": ["Any process that modulates the frequency, rate, or extent of granuloma formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080006", "l": "internode patterning", "d": ["Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0098883", "l": "synapse pruning", "d": ["A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032581", "l": "ER-dependent peroxisome organization", "d": ["A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0051274", "l": "beta-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007385", "l": "specification of segmental identity, abdomen", "d": ["The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0071971", "l": "extracellular exosome assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045150", "l": "acetoin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0033333", "l": "fin development", "d": ["The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0080171", "l": "lytic vacuole organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043090", "l": "amino acid import", "d": ["The directed movement of amino acids into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0031137", "l": "regulation of conjugation with cellular fusion", "d": ["Any process that modulates the rate or frequency of conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904440", "l": "positive regulation of iron ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022006", "l": "zona limitans intrathalamica formation", "d": ["The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071721", "l": "sodium-independent thromboxane transport", "d": ["The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902268", "l": "negative regulation of polyamine transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021589", "l": "cerebellum structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061431", "l": "cellular response to methionine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002084", "l": "protein depalmitoylation", "d": ["The removal of palymitoyl groups from a lipoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097151", "l": "positive regulation of inhibitory postsynaptic potential", "d": ["Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070935", "l": "3'-UTR-mediated mRNA stabilization", "d": ["An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035744", "l": "T-helper 1 cell cytokine production", "d": ["Any process that contributes to cytokine production by a T-helper 1 cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904973", "l": "positive regulation of viral translation", "d": ["Any process that activates or increases the frequency, rate or extent of viral translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030050", "l": "vesicle transport along actin filament", "d": ["Movement of a vesicle along an actin filament, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033610", "l": "oxalate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0035936", "l": "testosterone secretion", "d": ["The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009718", "l": "anthocyanin-containing compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0032070", "l": "regulation of deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902277", "l": "negative regulation of pancreatic amylase secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006028", "l": "galactosaminoglycan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051618", "l": "positive regulation of histamine uptake", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034503", "l": "protein localization to nucleolar rDNA repeats", "d": ["Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010151", "l": "chloroplast elongation", "d": ["Expansion of the chloroplast that usually precedes division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042998", "l": "positive regulation of Golgi to plasma membrane protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045585", "l": "positive regulation of cytotoxic T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.847638787057321", "identifiers": [{"i": "GO:0030851", "l": "granulocyte differentiation", "d": ["The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0072343", "l": "pancreatic stellate cell proliferation", "d": ["The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901877", "l": "negative regulation of calcium ion binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042037", "l": "peptidyl-histidine methylation, to form pros-methylhistidine", "d": ["The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001713", "l": "ectodermal cell fate determination", "d": ["The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.84203750265889", "identifiers": [{"i": "GO:0044087", "l": "regulation of cellular component biogenesis", "d": ["Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003028", "l": "regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling", "d": ["The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903397", "l": "positive regulation of secondary cell septum biogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905376", "l": "negative regulation of cytochrome-c oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090429", "l": "detection of endogenous biotic stimulus", "d": ["The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032666", "l": "regulation of interleukin-22 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-22 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904095", "l": "negative regulation of endosperm development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042617", "l": "paclitaxel biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009920", "l": "cell plate formation involved in plant-type cell wall biogenesis", "d": ["The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0009068", "l": "aspartate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045065", "l": "cytotoxic T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:0001763", "l": "morphogenesis of a branching structure", "d": ["The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010238", "l": "response to proline", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031655", "l": "negative regulation of heat dissipation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat dissipation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0021930", "l": "cerebellar granule cell precursor proliferation", "d": ["The multiplication or reproduction of neuroblasts that will give rise to granule cells. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150189", "l": "regulation of interleukin-32 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-32 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035284", "l": "brain segmentation", "d": ["Division of the brain into a series of semi-repetitive parts or segments."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0001578", "l": "microtubule bundle formation", "d": ["A process that results in a parallel arrangement of microtubules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080092", "l": "regulation of pollen tube growth", "d": ["Any process that modulates the frequency, rate or extent of pollen tube growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048711", "l": "positive regulation of astrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of astrocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002417", "l": "B cell antigen processing and presentation mediated by B cell receptor uptake of antigen", "d": ["B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043162", "l": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042702", "l": "uterine wall growth", "d": ["The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903435", "l": "positive regulation of constitutive secretory pathway", "d": ["Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0006306", "l": "DNA methylation", "d": ["The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048264", "l": "determination of ventral identity", "d": ["The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0051438", "l": "regulation of ubiquitin-protein transferase activity", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin transferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.752087540765736", "identifiers": [{"i": "GO:0006720", "l": "isoprenoid metabolic process", "d": ["The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070185", "l": "mitochondrial valyl-tRNA aminoacylation", "d": ["The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009118", "l": "regulation of nucleoside metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045843", "l": "negative regulation of striated muscle tissue development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0050921", "l": "positive regulation of chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045972", "l": "negative regulation of juvenile hormone secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901254", "l": "positive regulation of intracellular transport of viral material", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044639", "l": "envenomation resulting in modulation of complement activation, lectin pathway in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097117", "l": "guanylate kinase-associated protein clustering", "d": ["The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901892", "l": "negative regulation of cell septum assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048003", "l": "antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901926", "l": "cadinene metabolic process", "d": ["The chemical reactions and pathways involving cadinene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046832", "l": "negative regulation of RNA export from nucleus", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036512", "l": "trimming of second mannose on A branch", "d": ["The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070374", "l": "positive regulation of ERK1 and ERK2 cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019256", "l": "acrylonitrile catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044741", "l": "envenomation resulting in negative regulation of sensory perception of pain in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001106", "l": "regulation of Rho guanyl-nucleotide exchange factor activity", "d": ["Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048766", "l": "root hair initiation", "d": ["The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth."]}]} {"type": 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cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900573", "l": "emodin metabolic process", "d": ["The chemical reactions and pathways involving emodin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042893", "l": "polymyxin transport", "d": ["The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901937", "l": "beta-caryophyllene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 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"ascaroside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascaroside."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045456", "l": "ecdysteroid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900571", "l": "diorcinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of diorcinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016554", "l": "cytidine to uridine editing", "d": ["The conversion of a cytosine residue to uridine in an RNA molecule by deamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090006", "l": "regulation of linear element assembly", "d": ["Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902254", "l": "negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052782", "l": "amino disaccharide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0050913", "l": "sensory perception of bitter taste", "d": ["The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007301", "l": "female germline ring canal formation", "d": ["Assembly of the intercellular bridges that connect the germ-line cells of a female cyst."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002299", "l": "alpha-beta intraepithelial T cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035965", "l": "cardiolipin acyl-chain remodeling", "d": ["Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.9246167158351", "identifiers": [{"i": "GO:1901605", "l": "alpha-amino acid metabolic process", "d": ["The chemical reactions and pathways involving an alpha-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902998", "l": "positive regulation of neurofibrillary tangle assembly", "d": ["Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900940", "l": "positive regulation of (Z)-nonadeca-1,14-diene metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000005", "l": "negative regulation of metanephric S-shaped body morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070136", "l": "beta-1,2-oligomannoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901093", "l": "regulation of protein homotetramerization", "d": ["Any process that modulates the frequency, rate or extent of protein homotetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019475", "l": "L-lysine catabolic process to acetate", "d": ["The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000525", "l": "positive regulation of T cell costimulation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006784", "l": "heme A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072296", "l": "specification of metanephric loop of Henle identity", "d": ["The process in which the loop of Henle of the metanephric nephron acquires its identity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075274", "l": "negative regulation of zygosporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048657", "l": "anther wall tapetum cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900131", "l": "negative regulation of lipid binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901284", "l": "5,6,7,8-tetrahydromethanopterin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905263", "l": "positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination", "d": ["Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1902358", "l": "sulfate transmembrane transport", "d": ["The directed movement of sulfate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018253", "l": "peptide cross-linking via 5-imidazolinone glycine", "d": ["The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036040", "l": "curcumin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071703", "l": "detection of organic substance", "d": ["The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000853", "l": "negative regulation of corticosterone secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007426", "l": "tracheal outgrowth, open tracheal system", "d": ["The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0097476", "l": "spinal cord motor neuron migration", "d": ["The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0033967", "l": "box C/D RNA metabolic process", "d": ["The chemical reactions and pathways involving box C/D type small nucleolar RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.862324922820996", "identifiers": [{"i": "GO:0051249", "l": "regulation of lymphocyte activation", "d": ["Any process that modulates the frequency, rate or extent of lymphocyte activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048350", "l": "positive regulation of paraxial mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990064", "l": "ground tissue pattern formation", "d": ["The regionalization process that gives rise to the patterning of the ground tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904124", "l": "microglial cell migration", "d": ["The orderly movement of a microglial cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048344", "l": "paraxial mesodermal cell fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070433", "l": "negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905061", "l": "negative regulation of cardioblast proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0015780", "l": "nucleotide-sugar transmembrane transport", "d": ["The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099531", "l": "presynaptic process involved in chemical synaptic transmission", "d": ["The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902627", "l": "regulation of assembly of large subunit precursor of preribosome", "d": ["Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0098581", "l": "detection of external biotic stimulus", "d": ["The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120224", "l": "larynx development", "d": ["The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000518", "l": "negative regulation of T-helper 1 cell activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0106020", "l": "regulation of vesicle docking", "d": ["Any process that modulates the frequency, rate or extent of vesicle docking."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071389", "l": "cellular response to mineralocorticoid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048337", "l": "positive regulation of mesodermal cell fate specification", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006890", "l": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "d": ["The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003379", "l": "establishment of cell polarity involved in gastrulation cell migration", "d": ["The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0032508", "l": "DNA duplex unwinding", "d": ["The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.861052990773892", "identifiers": [{"i": "GO:0051240", "l": "positive regulation of multicellular organismal process", "d": ["Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0032466", "l": "negative regulation of cytokinesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099157", "l": "trans-synaptic signaling via exosome", "d": ["Transynaptic signaling in which the ligand is carried across the synapse by an exosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.14367232259255", "identifiers": [{"i": "GO:0031032", "l": "actomyosin structure organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002175", "l": "protein localization to paranode region of axon", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903383", "l": "regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901083", "l": "pyrrolizidine alkaloid metabolic process", "d": ["The chemical reactions and pathways involving pyrrolizidine alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0099633", "l": "protein localization to postsynaptic specialization membrane", "d": ["A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055005", "l": "ventricular cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120310", "l": "amastigogenesis", "d": ["The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042541", "l": "hemoglobin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061385", "l": "fibroblast proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045679", "l": "regulation of R8 cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of R8 differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000247", "l": "positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000464", "l": "endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905606", "l": "regulation of presynapse assembly", "d": ["Any process that modulates the frequency, rate or extent of presynapse assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901146", "l": "mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis", "d": ["Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046252", "l": "toluene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061408", "l": "positive regulation of transcription from RNA polymerase II promoter in response to heat stress", "d": ["Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.335885432862128", "identifiers": [{"i": "GO:0061351", "l": "neural precursor cell proliferation", "d": ["The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006157", "l": "deoxyadenosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046254", "l": "anaerobic toluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061334", "l": "cell rearrangement involved in Malpighian tubule morphogenesis", "d": ["The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902630", "l": "regulation of membrane hyperpolarization", "d": ["Any process that modulates the frequency, rate or extent of membrane hyperpolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002582", "l": "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010496", "l": "intercellular transport", "d": ["The movement of substances between cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120142", "l": "positive regulation of ecdysone receptor-mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042810", "l": "pheromone metabolic process", "d": ["The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042192", "l": "methylmercury biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903358", "l": "regulation of Golgi organization", "d": ["Any process that modulates the frequency, rate or extent of Golgi organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900209", "l": "negative regulation of cardiolipin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0048048", "l": "embryonic eye morphogenesis", "d": ["The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0060710", "l": "chorio-allantoic fusion", "d": ["The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0007099", "l": "centriole replication", "d": ["The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904529", "l": "regulation of actin filament binding", "d": ["Any process that modulates the frequency, rate or extent of actin filament binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0051797", "l": "regulation of hair follicle development", "d": ["Any process that modulates the frequency, rate or extent of hair follicle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0006911", "l": "phagocytosis, engulfment", "d": ["The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900451", "l": "positive regulation of glutamate receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098747", "l": "slow, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035832", "l": "berbamunine metabolic process", "d": ["The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070614", "l": "tungstate ion transport", "d": ["The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003195", "l": "tricuspid valve formation", "d": ["The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046533", "l": "negative regulation of photoreceptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036023", "l": "embryonic skeletal limb joint morphogenesis", "d": ["The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046464", "l": "acylglycerol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060663", "l": "apoptotic process involved in salivary gland cavitation", "d": ["Any apoptotic process in which the solid core of the gland is hollowed out to form the duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903630", "l": "regulation of aminoacyl-tRNA ligase activity", "d": ["Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902783", "l": "cellular response to decane", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0050772", "l": "positive regulation of axonogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of axonogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045176", "l": "apical protein localization", "d": ["Any process in which a protein is transported to, or maintained in, apical regions of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002037", "l": "negative regulation of L-glutamate import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052009", "l": "disruption by symbiont of host cell wall", "d": ["A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035131", "l": "post-embryonic pelvic fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060715", "l": "syncytiotrophoblast cell differentiation involved in labyrinthine layer development", "d": ["The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072112", "l": "podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0006536", "l": "glutamate metabolic process", "d": ["The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0009141", "l": "nucleoside triphosphate metabolic process", "d": ["The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060544", "l": "regulation of necroptotic process", "d": ["Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000152", "l": "regulation of ubiquitin-specific protease activity", "d": ["Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0017196", "l": "N-terminal peptidyl-methionine acetylation", "d": ["The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905755", "l": "protein localization to cytoplasmic microtubule", "d": ["A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046013", "l": "regulation of T cell homeostatic proliferation", "d": ["Any process that modulates the frequency, rate or extent of resting T cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905958", "l": "negative regulation of cellular response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0043084", "l": "penile erection", "d": ["The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061269", "l": "mesonephric glomerular mesangial cell proliferation involved in mesonephros development", "d": ["The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0043408", "l": "regulation of MAPK cascade", "d": ["Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032743", "l": "positive regulation of interleukin-2 production", "d": ["Any process that activates or increases the frequency, rate, or extent of interleukin-2 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0042819", "l": "vitamin B6 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903873", "l": "negative regulation of DNA recombinase mediator complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106048", "l": "spermidine deacetylation", "d": ["The modification of acetylspermadine by the removal of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032911", "l": "negative regulation of transforming growth factor beta1 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090451", "l": "cotyledon boundary formation", "d": ["The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019560", "l": "histidine catabolic process to hydantoin-5-propionate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.99638707280991", "identifiers": [{"i": "GO:0022408", "l": "negative regulation of cell-cell adhesion", "d": ["Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007021", "l": "tubulin complex assembly", "d": ["The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0006778", "l": "porphyrin-containing compound metabolic process", "d": ["The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006567", "l": "threonine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017199", "l": "N-terminal peptidyl-threonine acetylation", "d": ["The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.32380909477429", "identifiers": [{"i": "GO:0043069", "l": "negative regulation of programmed cell death", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061763", "l": "multivesicular body-lysosome fusion", "d": ["The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903302", "l": "regulation of pyruvate kinase activity", "d": ["Any process that modulates the frequency, rate or extent of pyruvate kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032326", "l": "Mo-molybdopterin cofactor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905660", "l": "mitotic checkpoint complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0072079", "l": "nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060891", "l": "limb granular cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046329", "l": "negative regulation of JNK cascade", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0051546", "l": "keratinocyte migration", "d": ["The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0061171", "l": "establishment of bipolar cell polarity", "d": ["The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0035935", "l": "androgen secretion", "d": ["The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900211", "l": "regulation of mesenchymal cell apoptotic process involved in metanephros development", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046101", "l": "hypoxanthine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035858", "l": "eosinophil fate determination", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0036102", "l": "leukotriene B4 metabolic process", "d": ["The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018355", "l": "protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine", "d": ["The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021897", "l": "forebrain astrocyte development", "d": ["The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007366", "l": "periodic partitioning by pair rule gene", "d": ["Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905317", "l": "inferior endocardial cushion morphogenesis", "d": ["The developmental process by which an inferior endocardial cushion is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006202", "l": "GMP catabolic process to guanine", "d": ["The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0050959", "l": "echolocation", "d": ["Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.42073205405498", "identifiers": [{"i": "GO:0033262", "l": "regulation of nuclear cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0090354", "l": "regulation of auxin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0007531", "l": "mating type determination", "d": ["Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001239", "l": "regulation of extrinsic apoptotic signaling pathway in absence of ligand", "d": ["Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1903322", "l": "positive regulation of protein modification by small protein conjugation or removal", "d": ["Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030887", "l": "positive regulation of myeloid dendritic cell activation", "d": ["Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902045", "l": "negative regulation of Fas signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018058", "l": "N-terminal protein amino acid deamination, from amino carbon", "d": ["The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903927", "l": "response to cyanide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001166", "l": "regulation of histone H2B ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of histone H2B ubiquitination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071215", "l": "cellular response to abscisic acid stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060474", "l": "positive regulation of flagellated sperm motility involved in capacitation", "d": ["The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034053", "l": "modulation by symbiont of host defense-related programmed cell death", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0007030", "l": "Golgi organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.804588241401973", "identifiers": [{"i": "GO:0032411", "l": "positive regulation of transporter activity", "d": ["Any process that activates or increases the activity of a transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032025", "l": "response to cobalt ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:1903313", "l": "positive regulation of mRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046260", "l": "trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905647", "l": "proline import across plasma membrane", "d": ["The directed movement of proline from outside of a cell into the cytoplasmic compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001756", "l": "somitogenesis", "d": ["The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900935", "l": "regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030708", "l": "germarium-derived female germ-line cyst encapsulation", "d": ["Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.401997675337611", "identifiers": [{"i": "GO:0090407", "l": "organophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900832", "l": "D-leucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0048521", "l": "negative regulation of behavior", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901447", "l": "positive regulation of response to propan-1-ol", "d": ["Any process that activates or increases the frequency, rate or extent of response to propan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035814", "l": "negative regulation of renal sodium excretion", "d": ["Any process that decreases the amount of sodium excreted in urine over a unit of time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010376", "l": "stomatal complex formation", "d": ["The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097701", "l": "response to pulsatile fluid shear stress", "d": ["Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.20349559345798", "identifiers": [{"i": "GO:0009056", "l": "catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0009129", "l": "pyrimidine nucleoside monophosphate metabolic process", "d": ["The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042081", "l": "GSI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0072111", "l": "cell proliferation involved in kidney development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035474", "l": "selective angioblast sprouting", "d": ["The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901777", "l": "mitomycin C biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mitomycin C."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070428", "l": "regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001176", "l": "regulation of mediator complex assembly", "d": ["Any process that modulates the frequency, rate or extent of mediator complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009290", "l": "DNA import into cell involved in transformation", "d": ["The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019524", "l": "keto-D-gluconate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075523", "l": "viral translational frameshifting", "d": ["A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042276", "l": "error-prone translesion synthesis", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000842", "l": "positive regulation of dehydroepiandrosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010801", "l": "negative regulation of peptidyl-threonine phosphorylation", "d": ["Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007100", "l": "mitotic centrosome separation", "d": ["Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0043254", "l": "regulation of protein-containing complex assembly", "d": ["Any process that modulates the frequency, rate or extent of protein complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051948", "l": "negative regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0140053", "l": "mitochondrial gene expression", "d": ["The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042121", "l": "alginic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904149", "l": "regulation of microglial cell mediated cytotoxicity", "d": ["Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.923665061460838", "identifiers": [{"i": "GO:0044414", "l": "suppression of host defenses by symbiont", "d": ["Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006382", "l": "adenosine to inosine editing", "d": ["The conversion of an adenosine residue to inosine in an RNA molecule by deamination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002329", "l": "pre-B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pre-B cell. 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The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002328", "l": "pro-B cell differentiation", "d": ["The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904584", "l": "cellular response to polyamine macromolecule", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051951", "l": "positive regulation of glutamate uptake involved in transmission of nerve impulse", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000638", "l": "regulation of SREBP signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of the SREBP signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001712", "l": "ectodermal cell fate commitment", "d": ["The cell differentiation process that results in commitment of a cell to become part of the ectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0015858", "l": "nucleoside transport", "d": ["The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990299", "l": "Bub1-Bub3 complex localization to kinetochore", "d": ["A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043313", "l": "regulation of neutrophil degranulation", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil degranulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061375", "l": "mammillotectal axonal tract development", "d": ["The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033335", "l": "anal fin development", "d": ["The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0048524", "l": "positive regulation of viral process", "d": ["Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097380", "l": "dorsal spinal cord interneuron anterior axon guidance", "d": ["The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0010633", "l": "negative regulation of epithelial cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090159", "l": "sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization", "d": ["The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021689", "l": "cerebellar molecular layer structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900876", "l": "nonadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving nonadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010126", "l": "mycothiol metabolic process", "d": ["The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0002384", "l": "hepatic immune response", "d": ["An immune response taking place in the liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007065", "l": "male meiosis sister chromatid cohesion", "d": ["The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044592", "l": "response to pullulan", "d": ["A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900602", "l": "endocrocin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of endocrocin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031508", "l": "pericentric heterochromatin formation", "d": ["The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0097168", "l": "mesenchymal stem cell proliferation", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904625", "l": "negative regulation of glycine secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006680", "l": "glucosylceramide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006545", "l": "glycine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1903353", "l": "regulation of nucleus organization", "d": ["Any process that modulates the frequency, rate or extent of nucleus organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090597", "l": "nematode male tail mating organ morphogenesis", "d": ["The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051622", "l": "negative regulation of norepinephrine uptake", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032265", "l": "XMP salvage", "d": ["Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0043984", "l": "histone H4-K16 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075241", "l": "positive regulation of zoospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900245", "l": "positive regulation of MDA-5 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903640", "l": "negative regulation of gastrin-induced gastric acid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000469", "l": "negative regulation of peroxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021506", "l": "anterior neuropore closure", "d": ["The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905329", "l": "sphingoid long-chain base transport", "d": ["The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006851", "l": "mitochondrial calcium ion transmembrane transport", "d": ["The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075303", "l": "positive regulation of basidiospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021651", "l": "rhombomere 1 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900228", "l": "regulation of single-species biofilm formation in or on host organism", "d": ["Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022027", "l": "interkinetic nuclear migration", "d": ["The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0090100", "l": "positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "d": ["Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0060972", "l": "left/right pattern formation", "d": ["The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009714", "l": "chalcone metabolic process", "d": ["The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905503", "l": "regulation of motile cilium assembly", "d": ["Any process that modulates the frequency, rate or extent of motile cilium assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002229", "l": "defense response to oomycetes", "d": ["Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021608", "l": "accessory nerve formation", "d": ["The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048658", "l": "anther wall tapetum development", "d": ["The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000798", "l": "negative regulation of amniotic stem cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0052709", "l": "N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097719", "l": "neural tissue regeneration", "d": ["The regrowth of neural tissue following its loss or destruction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042217", "l": "1-aminocyclopropane-1-carboxylate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022004", "l": "midbrain-hindbrain boundary maturation during brain development", "d": ["A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0010612", "l": "regulation of cardiac muscle adaptation", "d": ["Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905260", "l": "positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.058823935282668", "identifiers": [{"i": "GO:0001501", "l": "skeletal system development", "d": ["The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071401", "l": "cellular response to triglyceride", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903972", "l": "regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032914", "l": "positive regulation of transforming growth factor beta1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:1990266", "l": "neutrophil migration", "d": ["The movement of a neutrophil within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042466", "l": "chemokinesis", "d": ["A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990864", "l": "response to growth hormone-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051587", "l": "inhibition of dopamine uptake involved in synaptic transmission", "d": ["Any process that prevents the activation of the directed movement of dopamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048357", "l": "pedicel mucilage biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060629", "l": "regulation of homologous chromosome segregation", "d": ["Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0009268", "l": "response to pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035762", "l": "dorsal motor nucleus of vagus nerve morphogenesis", "d": ["The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901445", "l": "regulation of response to propan-1-ol", "d": ["Any process that modulates the frequency, rate or extent of response to propan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036001", "l": "'de novo' pyridoxal 5'-phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048148", "l": "behavioral response to cocaine", "d": ["Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061038", "l": "uterus morphogenesis", "d": ["The process in which anatomical structures of the uterus are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033519", "l": "phytyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002594", "l": "positive regulation of antigen processing and presentation via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904317", "l": "cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046003", "l": "negative regulation of syncytial blastoderm mitotic cell cycle", "d": ["Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060707", "l": "trophoblast giant cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120332", "l": "host-mediated regulation of oral microbiota composition", "d": ["The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032544", "l": "plastid translation", "d": ["The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.537094497236609", "identifiers": [{"i": "GO:0009066", "l": "aspartate family amino acid metabolic process", "d": ["The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0106259", "l": "cell-to-cell migration in host", "d": ["The directional movement of a symbiont from one host cell to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019571", "l": "D-arabinose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900950", "l": "regulation of 18-methylnonadec-1-ene biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009245", "l": "lipid A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010524", "l": "positive regulation of calcium ion transport into cytosol", "d": ["Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901764", "l": "phosphinothricin metabolic process", "d": ["The chemical reactions and pathways involving phosphinothricin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097329", "l": "response to antimetabolite", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072013", "l": "glomus development", "d": ["The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902123", "l": "(-)-pinoresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905840", "l": "positive regulation of telomeric D-loop disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0060079", "l": "excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001573", "l": "ganglioside metabolic process", "d": ["The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046005", "l": "positive regulation of circadian sleep/wake cycle, REM sleep", "d": ["Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902339", "l": "positive regulation of apoptotic process involved in morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001928", "l": "regulation of exocyst assembly", "d": ["Any process that modulates the frequency, rate or extent of exocyst assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002394", "l": "tolerance induction in gut-associated lymphoid tissue", "d": ["Tolerance induction taking place in the gut-associated lymphoid tissue (GALT)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071109", "l": "superior temporal gyrus development", "d": ["The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000719", "l": "photoreactive repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046273", "l": "lignan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.38033343679642", "identifiers": [{"i": "GO:0072690", "l": "single-celled organism vegetative growth phase", "d": ["A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048348", "l": "paraxial mesodermal cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070157", "l": "mitochondrial prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0022406", "l": "membrane docking", "d": ["The initial attachment of a membrane or protein to a target membrane. 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Tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0021772", "l": "olfactory bulb development", "d": ["The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062002", "l": "regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity", "d": ["Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001265", "l": "positive regulation of C-C chemokine binding", "d": ["Any process that activates or increases the frequency, rate or extent of C-C chemokine binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061344", "l": "regulation of cell adhesion involved in heart morphogenesis", "d": ["Any process that modulates the extent of cell adhesion contributing to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048397", "l": "positive regulation of intermediate mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044805", "l": "late nucleophagy", "d": ["A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000944", "l": "positive regulation of amylopectin metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034374", "l": "low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0097479", "l": "synaptic vesicle localization", "d": ["Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903705", "l": "positive regulation of siRNA processing", "d": ["Any process that activates or increases the frequency, rate or extent of siRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.728253302862804", "identifiers": [{"i": "GO:0019752", "l": "carboxylic acid metabolic process", "d": ["The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904432", "l": "regulation of ferrous iron binding", "d": ["Any process that modulates the frequency, rate or extent of ferrous iron binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900505", "l": "positive regulation of cellulosome assembly", "d": ["Any process that activates or increases the frequency, rate or extent of cellulosome assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048302", "l": "regulation of isotype switching to IgG isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0006067", "l": "ethanol metabolic process", "d": ["The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010751", "l": "negative regulation of nitric oxide mediated signal transduction", "d": ["Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO)."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0007129", "l": "homologous chromosome pairing at meiosis", "d": ["The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098817", "l": "evoked excitatory postsynaptic potential", "d": ["A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904299", "l": "negative regulation of transcytosis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.629028984204552", "identifiers": [{"i": "GO:0007626", "l": "locomotory behavior", "d": ["The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010838", "l": "positive regulation of keratinocyte proliferation", "d": ["Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0090136", "l": "epithelial cell-cell adhesion", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061184", "l": "positive regulation of dermatome development", "d": ["Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090727", "l": "positive regulation of brood size", "d": ["Any process that increases brood size. 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The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010614", "l": "negative regulation of cardiac muscle hypertrophy", "d": ["Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044487", "l": "envenomation resulting in modulation of transmission of nerve impulse in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.533887529881525", "identifiers": [{"i": "GO:0009896", "l": "positive regulation of catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002280", "l": "monocyte activation involved in immune response", "d": ["The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045471", "l": "response to ethanol", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050775", "l": "positive regulation of dendrite morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045324", "l": "late endosome to vacuole transport", "d": ["The directed movement of substances from late endosomes to the vacuole. 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This pathway is analogous to endosome to lysosome transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003354", "l": "negative regulation of cilium movement", "d": ["Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021797", "l": "forebrain anterior/posterior pattern specification", "d": ["The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:2000095", "l": "regulation of Wnt signaling pathway, planar cell polarity pathway", "d": ["Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0035418", "l": "protein localization to synapse", "d": ["Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048202", "l": "clathrin coating of Golgi vesicle", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043143", "l": "regulation of translation by machinery localization", "d": ["Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000777", "l": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia", "d": ["Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061246", "l": "establishment or maintenance of bipolar cell polarity regulating cell shape", "d": ["Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060197", "l": "cloacal septation", "d": ["The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045661", "l": "regulation of myoblast differentiation", "d": ["Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0033866", "l": "nucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048052", "l": "R1/R6 cell differentiation", "d": ["The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. 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Signaling never reaches a level of consciousness."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098920", "l": "retrograde trans-synaptic signaling by lipid", "d": ["Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003253", "l": "cardiac neural crest cell migration involved in outflow tract morphogenesis", "d": ["The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098818", "l": "hyperpolarization of postsynaptic membrane", "d": ["A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. 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A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0002204", "l": "somatic recombination of immunoglobulin genes involved in immune response", "d": ["The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0072526", "l": "pyridine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002633", "l": "positive regulation of granuloma formation", "d": ["Any process that activates or increases the frequency, rate, or extent of granuloma formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:1903708", "l": "positive regulation of hemopoiesis", "d": ["Any process that activates or increases the frequency, rate or extent of hemopoiesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903081", "l": "negative regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902425", "l": "positive regulation of attachment of mitotic spindle microtubules to kinetochore", "d": ["Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0009908", "l": "flower development", "d": ["The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035989", "l": "tendon development", "d": ["The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904480", "l": "positive regulation of intestinal absorption", "d": ["Any process that activates or increases the frequency, rate or extent of intestinal absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904339", "l": "negative regulation of dopaminergic neuron differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000038", "l": "regulation of stomatal complex development", "d": ["Any process that modulates the frequency, rate or extent of stomatal complex development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048718", "l": "cibarial fish-trap bristle morphogenesis", "d": ["The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. 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Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0032459", "l": "regulation of protein oligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein oligomerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051979", "l": "alginic acid acetylation", "d": ["The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140920", "l": "regulation of thermomorphogenesis", "d": ["Any process that modulates the frequency, rate or extent of thermomorphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048764", "l": "trichoblast maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060531", "l": "neuroendocrine cell differentiation involved in prostate gland acinus development", "d": ["The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901551", "l": "negative regulation of endothelial cell development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110155", "l": "NAD-cap decapping", "d": ["Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1900101", "l": "regulation of endoplasmic reticulum unfolded protein response", "d": ["Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.010064724098413", "identifiers": [{"i": "GO:0006956", "l": "complement activation", "d": ["Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140652", "l": "pyripyropene A biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyripyropene A."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0021543", "l": "pallium development", "d": ["The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042667", "l": "auditory receptor cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021933", "l": "radial glia guided migration of cerebellar granule cell", "d": ["The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0051278", "l": "fungal-type cell wall polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044747", "l": "pre-miRNA 3'-end processing", "d": ["Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0031645", "l": "negative regulation of nervous system process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043179", "l": "rhythmic excitation", "d": ["Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0038055", "l": "BMP secretion", "d": ["The controlled release of a member of the BMP family of proteins from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036245", "l": "cellular response to menadione", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905649", "l": "negative regulation of shell calcification", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900595", "l": "(+)-kotanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (+)-kotanin."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002786", "l": "regulation of antibacterial peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antibacterial peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000422", "l": "regulation of eosinophil chemotaxis", "d": ["Any process that modulates the frequency, rate or extent of eosinophil chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006606", "l": "protein import into nucleus", "d": ["The directed movement of a protein from the cytoplasm to the nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0014002", "l": "astrocyte development", "d": ["The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1901796", "l": "regulation of signal transduction by p53 class mediator", "d": ["Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042399", "l": "ectoine metabolic process", "d": ["The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070342", "l": "brown fat cell proliferation", "d": ["The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034356", "l": "NAD biosynthesis via nicotinamide riboside salvage pathway", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0140273", "l": "repair of mitotic kinetochore microtubule attachment defect", "d": ["The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048203", "l": "vesicle targeting, trans-Golgi to endosome", "d": ["The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018982", "l": "vanillin metabolic process", "d": ["The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007311", "l": "maternal specification of dorsal/ventral axis, oocyte, germ-line encoded", "d": ["Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110123", "l": "regulation of myotube cell migration", "d": ["Any process that modulates the frequency, rate or extent of myotube cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036519", "l": "chemorepulsion of serotonergic neuron axon", "d": ["The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001282", "l": "negative regulation of muscle cell chemotaxis toward tendon cell", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001178", "l": "positive regulation of mediator complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of mediator complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160054", "l": "microfibril assembly", "d": ["The aggregation, arrangement and bonding together of microfibril."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001284", "l": "regulation of BMP secretion", "d": ["Any process that modulates the frequency, rate or extent of BMP secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002672", "l": "positive regulation of B cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035863", "l": "dITP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.519625387257847", "identifiers": [{"i": "GO:0015872", "l": "dopamine transport", "d": ["The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903869", "l": "negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0097468", "l": "programmed cell death in response to reactive oxygen species", "d": ["Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. 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The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0043056", "l": "forward locomotion", "d": ["Anterior movement of an organism, following the direction of the head of the animal."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0011000", "l": "replication fork arrest at mating type locus", "d": ["A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0160032", "l": "Toll receptor ligand protein activation cascade", "d": ["A protein activation cascade that generates the active Toll receptor ligand and consists of the cascade of enzymatic reactions initiated by extracellular recognition factors, leading to the cleavage of the inactive form of spatzle family of ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034221", "l": "fungal-type cell wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060634", "l": "regulation of 4,6-pyruvylated galactose residue biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033595", "l": "response to genistein", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048535", "l": "lymph node development", "d": ["The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080037", "l": "negative regulation of cytokinin-activated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0050904", "l": "diapedesis", "d": ["The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110107", "l": "regulation of imaginal disc-derived wing vein specification", "d": ["Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075053", "l": "penetration peg formation", "d": ["The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046248", "l": "alpha-pinene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010087", "l": "phloem or xylem histogenesis", "d": ["The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060924", "l": "atrial cardiac muscle cell fate commitment", "d": ["The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035246", "l": "peptidyl-arginine N-methylation", "d": ["The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061560", "l": "cranial ganglion formation", "d": ["The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903568", "l": "negative regulation of protein localization to ciliary membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031147", "l": "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process", "d": ["The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0033214", "l": "siderophore-dependent iron import into cell", "d": ["A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0141085", "l": "regulation of inflammasome-mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of an inflammasome-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0060756", "l": "foraging behavior", "d": ["Behavior by which an organism locates food."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990555", "l": "mitochondrial oxaloacetate transmembrane transport", "d": ["The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.256999649495782", "identifiers": [{"i": "GO:0009314", "l": "response to radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903198", "l": "regulation of L-dopa decarboxylase activity", "d": ["Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034253", "l": "positive regulation of amide catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905769", "l": "positive regulation of double-stranded telomeric DNA binding", "d": ["Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:0046467", "l": "membrane lipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0046950", "l": "cellular ketone body metabolic process", "d": ["The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071040", "l": "nuclear polyadenylation-dependent antisense transcript catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002406", "l": "antigen sampling by M cells in mucosal-associated lymphoid tissue", "d": ["The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.516770421031836", "identifiers": [{"i": "GO:0060285", "l": "cilium-dependent cell motility", "d": ["Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.484282358461357", "identifiers": [{"i": "GO:0015749", "l": "monosaccharide transmembrane transport", "d": ["The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032904", "l": "negative regulation of nerve growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030007", "l": "intracellular potassium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019639", "l": "6-hydroxycineole catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.270819288512229", "identifiers": [{"i": "GO:0140014", "l": "mitotic nuclear division", "d": ["A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0070295", "l": "renal water absorption", "d": ["A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905490", "l": "negative regulation of sensory neuron axon guidance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0030224", "l": "monocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902035", "l": "positive regulation of hematopoietic stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021816", "l": "extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration", "d": ["The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016320", "l": "endoplasmic reticulum membrane fusion", "d": ["The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002509", "l": "central tolerance induction to self antigen", "d": ["Tolerance induction in the central lymphoid organs directed at self antigens."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048173", "l": "positive regulation of short-term neuronal synaptic plasticity", "d": ["A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035217", "l": "labial disc development", "d": ["Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106109", "l": "positive regulation of (R)-mevalonic acid biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072057", "l": "inner stripe development", "d": ["The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007072", "l": "positive regulation of transcription involved in exit from mitosis", "d": ["Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009139", "l": "pyrimidine nucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0032091", "l": "negative regulation of protein binding", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061906", "l": "autophagosome localization", "d": ["Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033031", "l": "positive regulation of neutrophil apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902663", "l": "negative regulation of peptidyl-L-cysteine S-palmitoylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0072711", "l": "cellular response to hydroxyurea", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902700", "l": "pentose catabolic process to butan-1-ol", "d": ["The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006020", "l": "inositol metabolic process", "d": ["The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1905874", "l": "regulation of postsynaptic density organization", "d": ["Any process that modulates the frequency, rate or extent of postsynaptic density organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0009408", "l": "response to heat", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:0019915", "l": "lipid storage", "d": ["The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903668", "l": "negative regulation of chemorepellent activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002679", "l": "respiratory burst involved in defense response", "d": ["A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0006303", "l": "double-strand break repair via nonhomologous end joining", "d": ["The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000023", "l": "regulation of lateral root development", "d": ["Any process that modulates the frequency, rate or extent of lateral root development."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031270", "l": "pseudopodium retraction", "d": ["The myosin-based contraction and retraction of a pseudopodium."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0009247", "l": "glycolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide)."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.125191863390697", "identifiers": [{"i": "GO:0045448", "l": "mitotic cell cycle, embryonic", "d": ["The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000973", "l": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "d": ["The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046325", "l": "negative regulation of glucose import", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.595126831462238", "identifiers": [{"i": "GO:0050866", "l": "negative regulation of cell activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0120029", "l": "proton export across plasma membrane", "d": ["The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048360", "l": "root cap mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030327", "l": "prenylated protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of prenylated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019392", "l": "glucarate metabolic process", "d": ["The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903637", "l": "negative regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140875", "l": "PR-toxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0010229", "l": "inflorescence development", "d": ["The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "53.435196929707985", "identifiers": [{"i": "GO:0016485", "l": "protein processing", "d": ["Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051164", "l": "L-xylitol metabolic process", "d": ["The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990910", "l": "response to hypobaric hypoxia", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902274", "l": "positive regulation of (R)-carnitine transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060155", "l": "platelet dense granule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905303", "l": "positive regulation of macropinocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of macropinocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150138", "l": "negative regulation of interleukin-37 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000331", "l": "regulation of terminal button organization", "d": ["Any process that modulates the frequency, rate or extent of terminal button organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046239", "l": "phthalate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.409568189683249", "identifiers": [{"i": "GO:0008015", "l": "blood circulation", "d": ["The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035801", "l": "adrenal cortex development", "d": ["The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048383", "l": "mesectoderm development", "d": ["The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070177", "l": "contractile vacuole discharge", "d": ["The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098038", "l": "non-replicative DNA transposition", "d": ["Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000445", "l": "positive regulation of toll-like receptor 21 signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0051615", "l": "histamine uptake", "d": ["The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905708", "l": "regulation of cell morphogenesis involved in conjugation with cellular fusion", "d": ["Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0006878", "l": "intracellular copper ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060086", "l": "circadian temperature homeostasis", "d": ["Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070667", "l": "negative regulation of mast cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of mast cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006168", "l": "adenine salvage", "d": ["Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075282", "l": "negative regulation of uredinium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070146", "l": "mitochondrial aspartyl-tRNA aminoacylation", "d": ["The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048296", "l": "regulation of isotype switching to IgA isotypes", "d": ["Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048841", "l": "regulation of axon extension involved in axon guidance", "d": ["Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150064", "l": "vertebrate eye-specific patterning", "d": ["Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903354", "l": "regulation of distal tip cell migration", "d": ["Any process that modulates the frequency, rate or extent of distal tip cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0071241", "l": "cellular response to inorganic substance", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902763", "l": "negative regulation of embryonic skeletal joint development", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0001834", "l": "trophectodermal cell proliferation", "d": ["The proliferation of cells in the trophectoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903898", "l": "negative regulation of PERK-mediated unfolded protein response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009691", "l": "cytokinin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900397", "l": "regulation of pyrimidine nucleotide biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901645", "l": "regulation of synoviocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of synoviocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902977", "l": "mitotic DNA replication preinitiation complex assembly", "d": ["Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002395", "l": "immune response in nasopharyngeal-associated lymphoid tissue", "d": ["An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006182", "l": "cGMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061910", "l": "autophagosome-endosome fusion", "d": ["The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035540", "l": "positive regulation of SNARE complex disassembly", "d": ["Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060160", "l": "negative regulation of dopamine receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0030716", "l": "oocyte fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904180", "l": "negative regulation of membrane depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046281", "l": "cinnamic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043116", "l": "negative regulation of vascular permeability", "d": ["Any process that reduces the extent to which blood vessels can be pervaded by fluid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075322", "l": "regulation of oomycete sporangium development", "d": ["Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003409", "l": "optic cup structural organization", "d": ["The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901261", "l": "regulation of sorocarp spore cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032213", "l": "regulation of telomere maintenance via semi-conservative replication", "d": ["Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900840", "l": "regulation of helvolic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048791", "l": "calcium ion-regulated exocytosis of neurotransmitter", "d": ["The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901949", "l": "5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035491", "l": "positive regulation of leukotriene production involved in inflammatory response", "d": ["Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097314", "l": "apoptosome assembly", "d": ["The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019484", "l": "beta-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071469", "l": "cellular response to alkaline pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021815", "l": "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration", "d": ["Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900158", "l": "negative regulation of bone mineralization involved in bone maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160034", "l": "positive regulation of Toll receptor ligand protein activation cascade", "d": ["Any process that activates or increases the frequency, rate or extent of Toll receptor ligand protein activation cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904495", "l": "negative regulation of substance P secretion, neurotransmission", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042853", "l": "L-alanine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048219", "l": "inter-Golgi cisterna vesicle-mediated transport", "d": ["The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0099129", "l": "cochlear outer hair cell electromotile response", "d": ["A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904434", "l": "positive regulation of ferrous iron binding", "d": ["Any process that activates or increases the frequency, rate or extent of ferrous iron binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032699", "l": "negative regulation of interleukin-16 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033312", "l": "chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a", "d": ["The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903845", "l": "negative regulation of cellular response to transforming growth factor beta stimulus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038105", "l": "sequestering of TGFbeta from receptor via TGFbeta binding", "d": ["Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006032", "l": "chitin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900068", "l": "negative regulation of cellular response to alkaline pH", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905271", "l": "regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060874", "l": "posterior semicircular canal development", "d": ["The progession of the posterior semicircular canal from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019928", "l": "peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid", "d": ["The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035124", "l": "embryonic caudal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0014862", "l": "regulation of skeletal muscle contraction by chemo-mechanical energy conversion", "d": ["Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000283", "l": "negative regulation of amino acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097029", "l": "mature conventional dendritic cell differentiation", "d": ["The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046601", "l": "positive regulation of centriole replication", "d": ["Any process that activates or increases the frequency, rate or extent of centriole replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061183", "l": "regulation of dermatome development", "d": ["Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905042", "l": "negative regulation of epithelium regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046600", "l": "negative regulation of centriole replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900678", "l": "regulation of ferricrocin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902300", "l": "galactarate transmembrane transport", "d": ["The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042685", "l": "cardioblast cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002006", "l": "vasoconstriction by vasopressin involved in systemic arterial blood pressure control", "d": ["The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904234", "l": "positive regulation of aconitate hydratase activity", "d": ["Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0046940", "l": "nucleoside monophosphate phosphorylation", "d": ["The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904218", "l": "negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021914", "l": "negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010082", "l": "regulation of root meristem growth", "d": ["Any process involved in maintaining the size and shape of a root meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090472", "l": "dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0090034", "l": "regulation of chaperone-mediated protein complex assembly", "d": ["Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905881", "l": "positive regulation of oogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090475", "l": "lys-lys specific dibasic protein processing", "d": ["Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042468", "l": "klinokinesis", "d": ["The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900662", "l": "negative regulation of emericellamide A biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904850", "l": "negative regulation of establishment of protein localization to telomere", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048214", "l": "regulation of Golgi vesicle fusion to target membrane", "d": ["Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000013", "l": "regulation of arginine biosynthetic process via ornithine", "d": ["Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052780", "l": "chitobiose metabolic process", "d": ["The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002338", "l": "B-1b B cell differentiation", "d": ["The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002853", "l": "negative regulation of T cell mediated cytotoxicity directed against tumor cell target", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031408", "l": "oxylipin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905638", "l": "negative regulation of mitochondrial mRNA catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046500", "l": "S-adenosylmethionine metabolic process", "d": ["The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070237", "l": "positive regulation of activation-induced cell death of T cells", "d": ["Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900872", "l": "pentadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving pentadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0030833", "l": "regulation of actin filament polymerization", "d": ["Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048291", "l": "isotype switching to IgG isotypes", "d": ["The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046116", "l": "queuosine metabolic process", "d": ["The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070217", "l": "transcription factor TFIIIB complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903190", "l": "glyoxal catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glyoxal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901536", "l": "negative regulation of DNA demethylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0009826", "l": "unidimensional cell growth", "d": ["The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019661", "l": "glucose catabolic process to lactate via pyruvate", "d": ["The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000053", "l": "argininosuccinate metabolic process", "d": ["The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate."]}]} {"type": "biolink:BiologicalProcess", "ic": "31.874650222196383", "identifiers": [{"i": "GO:0003008", "l": "system process", "d": ["A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0001964", "l": "startle response", "d": ["An action or movement due to the application of a sudden unexpected stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0008218", "l": "bioluminescence", "d": ["The production of light by certain enzyme-catalyzed reactions in cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098717", "l": "pantothenate import across plasma membrane", "d": ["The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002668", "l": "negative regulation of T cell anergy", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048067", "l": "cuticle pigmentation", "d": ["Establishment of a pattern of pigment in the cuticle of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904792", "l": "positive regulation of shelterin complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of shelterin complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902027", "l": "positive regulation of cartilage condensation", "d": ["Any process that activates or increases the frequency, rate or extent of cartilage condensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905444", "l": "negative regulation of clathrin coat assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.703977263494721", "identifiers": [{"i": "GO:0016051", "l": "carbohydrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0060993", "l": "kidney morphogenesis", "d": ["Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:2000117", "l": "negative regulation of cysteine-type endopeptidase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036386", "l": "bacterial nucleoid packaging", "d": ["A process in which chromosomal DNA and associated proteins organize into a compact, orderly bacterial nucleoid. Often resulting in DNA supercoiling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044740", "l": "negative regulation of sensory perception of pain in another organism", "d": ["A process that negatively regulates the sensory perception of pain in a different organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032654", "l": "regulation of interleukin-11 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-11 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0003022", "l": "detection of pH by chemoreceptor signaling", "d": ["The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042761", "l": "very long-chain fatty acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905852", "l": "positive regulation of backward locomotion", "d": ["Any process that activates or increases the frequency, rate or extent of backward locomotion."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903792", "l": "negative regulation of monoatomic anion transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anion transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0007365", "l": "periodic partitioning", "d": ["The regionalization process that divides the spatial regions of an embryo into serially repeated regions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150072", "l": "positive regulation of arginase activity", "d": ["Any process that activates or increases the frequency, rate or extent of arginase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001256", "l": "regulation of store-operated calcium entry", "d": ["Any process that modulates the frequency, rate or extent of store-operated calcium entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0060236", "l": "regulation of mitotic spindle organization", "d": ["Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015752", "l": "D-ribose transmembrane transport", "d": ["The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0042451", "l": "purine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0006551", "l": "leucine metabolic process", "d": ["The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904570", "l": "negative regulation of selenocysteine incorporation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007451", "l": "dorsal/ventral lineage restriction, imaginal disc", "d": ["Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:1901989", "l": "positive regulation of cell cycle phase transition", "d": ["Any process that activates or increases the frequency, rate or extent of cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904840", "l": "positive regulation of male germ-line stem cell asymmetric division", "d": ["Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.10017597303252", "identifiers": [{"i": "GO:0034651", "l": "cortisol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140235", "l": "RNA polyadenylation at postsynapse", "d": ["A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "44.414374882708088", "identifiers": [{"i": "GO:0032940", "l": "secretion by cell", "d": ["The controlled release of a substance by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035021", "l": "negative regulation of Rac protein signal transduction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903970", "l": "negative regulation of response to macrophage colony-stimulating factor", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010081", "l": "regulation of inflorescence meristem growth", "d": ["Any process involved in maintaining the size and shape of an inflorescence meristem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051586", "l": "positive regulation of dopamine uptake involved in synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1902682", "l": "protein localization to pericentric heterochromatin", "d": ["A process in which a protein is transported to, or maintained in the pericentric heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000131", "l": "regulation of tyramine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of tyramine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009630", "l": "gravitropism", "d": ["The orientation of plant parts under the stimulation of gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060523", "l": "prostate epithelial cord elongation", "d": ["The developmental growth process in which solid chords of prostate epithelium increase in length."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0120064", "l": "stomach pylorus smooth muscle contraction", "d": ["A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:1902319", "l": "DNA strand elongation involved in nuclear cell cycle DNA replication", "d": ["Any DNA strand elongation that is involved in nuclear cell cycle DNA replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000465", "l": "exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.300836423492882", "identifiers": [{"i": "GO:1990778", "l": "protein localization to cell periphery", "d": ["A process in which a protein is transported to, or maintained in, the cell periphery."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098874", "l": "spike train", "d": ["A series of sequential, propagated action potentials occurring in a single cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900683", "l": "regulation of fumonisin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046877", "l": "regulation of saliva secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903838", "l": "negative regulation of mRNA 3'-UTR binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071473", "l": "cellular response to cation stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.185623981295834", "identifiers": [{"i": "GO:0002652", "l": "regulation of tolerance induction dependent upon immune response", "d": ["Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060272", "l": "embryonic skeletal joint morphogenesis", "d": ["The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090550", "l": "response to molybdenum starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021887", "l": "hypothalamus gonadotrophin-releasing hormone neuron fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0090031", "l": "positive regulation of steroid hormone biosynthetic process", "d": ["Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:2000924", "l": "regulation of cellodextrin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellodextrin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019805", "l": "quinolinate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045458", "l": "recombination within rDNA repeats", "d": ["Genetic recombination within the DNA of the genes coding for ribosomal RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904214", "l": "positive regulation of iodide transmembrane transport", "d": ["Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048369", "l": "lateral mesoderm morphogenesis", "d": ["The process in which the anatomical structures of the lateral mesoderm are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098678", "l": "viral tropism switching", "d": ["A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905605", "l": "positive regulation of blood-brain barrier permeability", "d": ["Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902370", "l": "regulation of tRNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of tRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036255", "l": "response to methylamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019557", "l": "histidine catabolic process to glutamate and formate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044832", "l": "induction by virus of host cytokine production", "d": ["The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061390", "l": "positive regulation of direction of cell growth", "d": ["Any process that increases the direction of cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060660", "l": "epidermis morphogenesis involved in nipple formation", "d": ["The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0030174", "l": "regulation of DNA-templated DNA replication initiation", "d": ["Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090334", "l": "regulation of cell wall (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035367", "l": "positive regulation of thymine transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0050860", "l": "negative regulation of T cell receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.946107901282822", "identifiers": [{"i": "GO:0007596", "l": "blood coagulation", "d": ["The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901954", "l": "regulation of retrograde dense core granule transport", "d": ["Any process that modulates the frequency, rate or extent of retrograde dense core granule transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051888", "l": "positive regulation of timing of exogen", "d": ["Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042059", "l": "negative regulation of epidermal growth factor receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.240948556675605", "identifiers": [{"i": "GO:0050975", "l": "sensory perception of touch", "d": ["The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009768", "l": "photosynthesis, light harvesting in photosystem I", "d": ["After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090149", "l": "mitochondrial membrane fission", "d": ["A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903636", "l": "regulation of protein insertion into mitochondrial outer membrane", "d": ["Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007004", "l": "telomere maintenance via telomerase", "d": ["The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904962", "l": "plastid to vacuole vesicle-mediated transport", "d": ["The vesicle-mediated and directed movement of substances from plastid to vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014814", "l": "axon regeneration at neuromuscular junction", "d": ["The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018959", "l": "aerobic phenol-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045107", "l": "intermediate filament polymerization", "d": ["Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150141", "l": "negative regulation of CD86 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033375", "l": "protease localization to T cell secretory granule", "d": ["Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904916", "l": "transmembrane L-lysine transport from lysosomal lumen to cytosol", "d": ["The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106147", "l": "fraxetin biosynthesis", "d": ["The chemical reactions and pathways resulting in the formation of fraxetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0052545", "l": "callose localization", "d": ["Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1904978", "l": "regulation of endosome organization", "d": ["Any process that modulates the frequency, rate or extent of endosome organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000143", "l": "negative regulation of DNA-templated transcription initiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071965", "l": "multicellular organismal locomotion", "d": ["Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071895", "l": "odontoblast differentiation", "d": ["The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044083", "l": "perturbation of host Rho protein signal transduction", "d": ["A process in which a symbiont alters a Rho protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1990768", "l": "gastric mucosal blood circulation", "d": ["The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070956", "l": "negative regulation of neutrophil mediated killing of bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045643", "l": "regulation of eosinophil differentiation", "d": ["Any process that modulates the frequency, rate or extent of eosinophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1905915", "l": "regulation of cell differentiation involved in phenotypic switching", "d": ["Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905089", "l": "regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0050976", "l": "detection of mechanical stimulus involved in sensory perception of touch", "d": ["The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902993", "l": "positive regulation of amyloid precursor protein catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090731", "l": "cellular response to very-low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905069", "l": "allantois development", "d": ["The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0031548", "l": "regulation of brain-derived neurotrophic factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901385", "l": "regulation of voltage-gated calcium channel activity", "d": ["Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007455", "l": "eye-antennal disc morphogenesis", "d": ["The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001954", "l": "positive regulation of cell-matrix adhesion", "d": ["Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141029", "l": "disruption by symbiont of host focal adhesion", "d": ["The process by which a symbiont disupts host focal adhesion in its host."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042492", "l": "gamma-delta T cell differentiation", "d": ["The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000917", "l": "positive regulation of glucuronoxylan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900651", "l": "positive regulation of dehydroaustinol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904127", "l": "regulation of convergent extension involved in somitogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010417", "l": "glucuronoxylan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0019566", "l": "arabinose metabolic process", "d": ["The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0061339", "l": "establishment or maintenance of monopolar cell polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904308", "l": "cellular response to desipramine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0045932", "l": "negative regulation of muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0060191", "l": "regulation of lipase activity", "d": ["Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014887", "l": "cardiac muscle adaptation", "d": ["The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0060573", "l": "cell fate specification involved in pattern specification", "d": ["The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.786315444102826", "identifiers": [{"i": "GO:0072078", "l": "nephron tubule morphogenesis", "d": ["The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2001027", "l": "negative regulation of endothelial cell chemotaxis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140067", "l": "peptidyl-lysine butyrylation", "d": ["The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0008039", "l": "synaptic target recognition", "d": ["The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000125", "l": "regulation of octopamine or tyramine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071259", "l": "cellular response to magnetism", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901062", "l": "guaiacyl lignin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007107", "l": "membrane addition at site of cytokinesis", "d": ["Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019542", "l": "propionate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032481", "l": "positive regulation of type I interferon production", "d": ["Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0043542", "l": "endothelial cell migration", "d": ["The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904471", "l": "negative regulation of endothelin production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039724", "l": "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity", "d": ["Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905553", "l": "regulation of blood vessel branching", "d": ["Any process that modulates the frequency, rate or extent of blood vessel branching."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0046134", "l": "pyrimidine nucleoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019745", "l": "pentacyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032618", "l": "interleukin-15 production", "d": ["The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019559", "l": "histidine catabolic process to imidazol-5-yl-lactate", "d": ["The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0031345", "l": "negative regulation of cell projection organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044663", "l": "establishment or maintenance of cell type involved in phenotypic switching", "d": ["A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061529", "l": "epinephrine secretion, neurotransmission", "d": ["The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0019627", "l": "urea metabolic process", "d": ["The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045167", "l": "asymmetric protein localization involved in cell fate determination", "d": ["Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032467", "l": "positive regulation of cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0045579", "l": "positive regulation of B cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of B cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.133821031307569", "identifiers": [{"i": "GO:0042060", "l": "wound healing", "d": ["The series of events that restore integrity to a damaged tissue, following an injury."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903914", "l": "negative regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.890448006900634", "identifiers": [{"i": "GO:0051241", "l": "negative regulation of multicellular organismal process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042459", "l": "octopine catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075135", "l": "symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction", "d": ["A process in which a virus interferes with, inhibits or disrupts a calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019876", "l": "nylon catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0007130", "l": "synaptonemal complex assembly", "d": ["The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0044621", "l": "modulation of cell migration in another organism", "d": ["The process in which an organism effects a change in the process of cell migration in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000475", "l": "maturation of 2S rRNA", "d": ["Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010839", "l": "negative regulation of keratinocyte proliferation", "d": ["Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043278", "l": "response to morphine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:1903729", "l": "regulation of plasma membrane organization", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901562", "l": "response to paraquat", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.968527344256771", "identifiers": [{"i": "GO:0007617", "l": "mating behavior", "d": ["The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019060", "l": "intracellular transport of viral protein in host cell", "d": ["The directed movement of a viral protein within the host cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018935", "l": "aerobic nitrilotriacetate metabolic process", "d": ["The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905652", "l": "negative regulation of artery morphogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.975435936396124", "identifiers": [{"i": "GO:0048827", "l": "phyllome development", "d": ["The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002939", "l": "tRNA N1-guanine methylation", "d": ["The process whereby a guanine in tRNA is methylated at position N1 of the guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0072010", "l": "glomerular epithelium development", "d": ["The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904417", "l": "positive regulation of xenophagy", "d": ["Any process that activates or increases the frequency, rate or extent of xenophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070927", "l": "negative regulation of ATP:ADP antiporter activity", "d": ["Any process that stops or reduces the activity of an ATP:ADP antiporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904051", "l": "regulation of protein targeting to vacuole involved in autophagy", "d": ["Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120198", "l": "positive regulation of imaginal disc-derived wing size", "d": ["Any process that increases the size of an imaginal disc-derived wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900494", "l": "regulation of butyryl-CoA biosynthetic process from acetyl-CoA", "d": ["Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106034", "l": "protein maturation by [2Fe-2S] cluster transfer", "d": ["The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0061062", "l": "regulation of nematode larval development", "d": ["Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902356", "l": "oxaloacetate(2-) transmembrane transport", "d": ["The directed movement of oxaloacetate(2-) across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033387", "l": "putrescine biosynthetic process from ornithine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051524", "l": "cell growth mode switching, bipolar to monopolar", "d": ["The process in which a cell switches from bipolar cell growth to monopolar cell growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045051", "l": "protein insertion into ER membrane by internal uncleaved signal-anchor sequence", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900976", "l": "positive regulation of tatiopterin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035606", "l": "peptidyl-cysteine S-trans-nitrosylation", "d": ["Transfer of a nitric oxide (NO) group from one cysteine residue to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032511", "l": "late endosome to vacuole transport via multivesicular body sorting pathway", "d": ["The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.491863471761647", "identifiers": [{"i": "GO:0003007", "l": "heart morphogenesis", "d": ["The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042686", "l": "regulation of cardioblast cell fate specification", "d": ["Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002788", "l": "regulation of antifungal peptide production", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904021", "l": "negative regulation of G protein-coupled receptor internalization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014894", "l": "response to denervation involved in regulation of muscle adaptation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021736", "l": "globose nucleus development", "d": ["The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900183", "l": "regulation of xanthone-containing compound biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0150077", "l": "regulation of neuroinflammatory response", "d": ["Any process that modulates the frequency, rate or extent of neuroinflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061680", "l": "Entner-Doudoroff pathway through gluconate to D-glyceraldehyde", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0072016", "l": "glomerular parietal epithelial cell development", "d": ["The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006734", "l": "NADH metabolic process", "d": ["The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048656", "l": "anther wall tapetum formation", "d": ["The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002917", "l": "regulation of peripheral B cell anergy", "d": ["Any process that modulates the frequency, rate, or extent of peripheral B cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904041", "l": "regulation of cystathionine beta-synthase activity", "d": ["Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:1903351", "l": "cellular response to dopamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902492", "l": "positive regulation of sperm capacitation", "d": ["Any process that activates or increases the frequency, rate or extent of sperm capacitation."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0061492", "l": "asymmetric protein localization to old or new spindle pole body", "d": ["Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090461", "l": "intracellular glutamate homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003200", "l": "endocardial cushion to mesenchymal transition involved in heart chamber septation", "d": ["A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:2000895", "l": "hemicellulose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a hemicellulose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019335", "l": "3-methylquinoline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0030952", "l": "establishment or maintenance of cytoskeleton polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900558", "l": "austinol metabolic process", "d": ["The chemical reactions and pathways involving austinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046468", "l": "phosphatidyl-N-monomethylethanolamine metabolic process", "d": ["The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033603", "l": "positive regulation of dopamine secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902940", "l": "positive regulation of intracellular calcium activated chloride channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.042516761614237", "identifiers": [{"i": "GO:0018394", "l": "peptidyl-lysine acetylation", "d": ["The acetylation of peptidyl-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0005984", "l": "disaccharide metabolic process", "d": ["The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001028", "l": "positive regulation of endothelial cell chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901819", "l": "alpha-zeacarotene metabolic process", "d": ["The chemical reactions and pathways involving alpha-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106089", "l": "negative regulation of cell adhesion involved in sprouting angiogenesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098964", "l": "anterograde dendritic transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904015", "l": "cellular response to serotonin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002458", "l": "peripheral T cell tolerance induction", "d": ["Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072208", "l": "metanephric smooth muscle tissue development", "d": ["The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905465", "l": "regulation of G-quadruplex DNA unwinding", "d": ["Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990253", "l": "cellular response to leucine starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034260", "l": "negative regulation of GTPase activity", "d": ["Any process that stops or reduces the rate of GTP hydrolysis by a GTPase."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.677603159285916", "identifiers": [{"i": "GO:0006935", "l": "chemotaxis", "d": ["The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990522", "l": "tail spike morphogenesis", "d": ["The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036504", "l": "Golgi membrane fusion", "d": ["The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905539", "l": "regulation of postsynapse to nucleus signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0008348", "l": "negative regulation of antimicrobial humoral response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0046688", "l": "response to copper ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001105", "l": "maltoheptaose transport", "d": ["The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097012", "l": "response to granulocyte macrophage colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900126", "l": "negative regulation of hyaluronan biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021694", "l": "cerebellar Purkinje cell layer formation", "d": ["The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042725", "l": "thiamine-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000426", "l": "micropexophagy", "d": ["Degradation of a peroxisome by lysosomal microautophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990579", "l": "peptidyl-serine trans-autophosphorylation", "d": ["The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.597844352697123", "identifiers": [{"i": "GO:0031214", "l": "biomineral tissue development", "d": ["Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019325", "l": "anaerobic fructose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902484", "l": "Sertoli cell apoptotic process", "d": ["Any apoptotic process in a Sertoli cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900085", "l": "negative regulation of peptidyl-tyrosine autophosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070156", "l": "mitochondrial phenylalanyl-tRNA aminoacylation", "d": ["The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901667", "l": "negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043506", "l": "regulation of JUN kinase activity", "d": ["Any process that modulates the frequency, rate or extent of JUN kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0051899", "l": "membrane depolarization", "d": ["The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901194", "l": "negative regulation of formation of translation preinitiation complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033352", "l": "UDP-D-apiose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902921", "l": "poly(hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006585", "l": "dopamine biosynthetic process from tyrosine", "d": ["The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045959", "l": "negative regulation of complement activation, classical pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051072", "l": "4,6-pyruvylated galactose residue biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0016138", "l": "glycoside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032764", "l": "negative regulation of mast cell cytokine production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.917961030569273", "identifiers": [{"i": "GO:0033365", "l": "protein localization to organelle", "d": ["A process in which a protein is transported to, or maintained in, a location within an organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019704", "l": "peptidyl-L-cysteine S-myristoylation", "d": ["The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905068", "l": "positive regulation of canonical Wnt signaling pathway involved in heart development", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035880", "l": "embryonic nail plate morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903784", "l": "positive regulation of sodium ion import across plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006614", "l": "SRP-dependent cotranslational protein targeting to membrane", "d": ["The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051554", "l": "flavonol metabolic process", "d": ["The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071572", "l": "histone H3-K56 deacetylation", "d": ["The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.86427600823658", "identifiers": [{"i": "GO:0010256", "l": "endomembrane system organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033606", "l": "chemokine receptor transport within lipid bilayer", "d": ["The directed movement of a chemokine receptor within a lipid bilayer."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009159", "l": "deoxyribonucleoside monophosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044394", "l": "protein malonylation", "d": ["The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034445", "l": "negative regulation of plasma lipoprotein oxidation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006789", "l": "bilirubin conjugation", "d": ["The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.80645264856247", "identifiers": [{"i": "GO:0009307", "l": "DNA restriction-modification system", "d": ["A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901919", "l": "positive regulation of exoribonuclease activity", "d": ["Any process that activates or increases the frequency, rate or extent of exoribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0000712", "l": "resolution of meiotic recombination intermediates", "d": ["The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110077", "l": "vesicle-mediated intercellular transport", "d": ["A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045218", "l": "zonula adherens maintenance", "d": ["Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060112", "l": "generation of ovulation cycle rhythm", "d": ["The process which controls the timing of the type of sexual cycle seen in female mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000352", "l": "negative regulation of endothelial cell apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032665", "l": "regulation of interleukin-21 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-21 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051107", "l": "negative regulation of DNA ligation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:2000211", "l": "regulation of glutamate metabolic process", "d": ["Any process that modulates the frequency, rate or extent of glutamate metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070099", "l": "regulation of chemokine-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035308", "l": "negative regulation of protein dephosphorylation", "d": ["Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.83403442609314", "identifiers": [{"i": "GO:0001894", "l": "tissue homeostasis", "d": ["A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0021921", "l": "regulation of cell proliferation in dorsal spinal cord", "d": ["The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072701", "l": "cellular response to bismuth", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900906", "l": "negative regulation of hexadecanal metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904924", "l": "negative regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045899", "l": "positive regulation of RNA polymerase II transcription preinitiation complex assembly", "d": ["Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071487", "l": "cellular response to low light intensity stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046223", "l": "aflatoxin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0046532", "l": "regulation of photoreceptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001036", "l": "negative regulation of tongue muscle cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0019684", "l": "photosynthesis, light reaction", "d": ["The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032571", "l": "response to vitamin K", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035200", "l": "leg disc anterior/posterior pattern formation", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031665", "l": "negative regulation of lipopolysaccharide-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030391", "l": "fructosamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0045980", "l": "negative regulation of nucleotide metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.435418415656045", "identifiers": [{"i": "GO:0061323", "l": "cell proliferation involved in heart morphogenesis", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046850", "l": "regulation of bone remodeling", "d": ["Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045900", "l": "negative regulation of translational elongation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0006760", "l": "folic acid-containing compound metabolic process", "d": ["The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046250", "l": "limonene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0042706", "l": "eye photoreceptor cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903062", "l": "regulation of reverse cholesterol transport", "d": ["Any process that modulates the frequency, rate or extent of reverse cholesterol transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061331", "l": "epithelial cell proliferation involved in Malpighian tubule morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032226", "l": "positive regulation of synaptic transmission, dopaminergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905136", "l": "dethiobiotin import across plasma membrane", "d": ["The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140018", "l": "regulation of cytoplasmic translational fidelity", "d": ["Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120194", "l": "regulation of anther dehiscence", "d": ["Any process involved in the dehiscence of an anther to release the pollen grains contained within it."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902760", "l": "Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043045", "l": "post-fertilization epigenetic regulation of gene expression", "d": ["A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051901", "l": "positive regulation of mitochondrial depolarization", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060758", "l": "foraging behavior by probing substrate", "d": ["Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1902743", "l": "regulation of lamellipodium organization", "d": ["Any process that modulates the frequency, rate or extent of lamellipodium organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0098653", "l": "centromere clustering", "d": ["The process by which centromeres/kinetochores become localized to clusters."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.473322228407739", "identifiers": [{"i": "GO:0031670", "l": "cellular response to nutrient", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0032868", "l": "response to insulin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097172", "l": "N-acetylmuramic acid metabolic process", "d": ["The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006120", "l": "mitochondrial electron transport, NADH to ubiquinone", "d": ["The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018969", "l": "thiocyanate metabolic process", "d": ["The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006718", "l": "juvenile hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019896", "l": "axonal transport of mitochondrion", "d": ["The directed movement of mitochondria along microtubules in nerve cell axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042941", "l": "D-alanine transport", "d": ["The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052519", "l": "positive regulation of nutrient release by symbiont", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0070841", "l": "inclusion body assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form an inclusion body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034972", "l": "histone H3-R26 methylation", "d": ["The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902567", "l": "negative regulation of eosinophil activation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034148", "l": "negative regulation of toll-like receptor 5 signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007524", "l": "adult visceral muscle development", "d": ["The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901091", "l": "negative regulation of protein tetramerization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030206", "l": "chondroitin sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051677", "l": "pullulan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021531", "l": "spinal cord radial glial cell differentiation", "d": ["The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051676", "l": "pullulan metabolic process", "d": ["The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901975", "l": "glycerate transmembrane transport", "d": ["The process in which glycerate is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904171", "l": "negative regulation of bleb assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060914", "l": "heart formation", "d": ["The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990418", "l": "response to insulin-like growth factor stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048370", "l": "lateral mesoderm formation", "d": ["The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071387", "l": "cellular response to cortisol stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0043288", "l": "apocarotenoid metabolic process", "d": ["The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033247", "l": "regulation of penicillin catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060032", "l": "notochord regression", "d": ["The developmental process in which the stucture of the notochord is destroyed in an embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071280", "l": "cellular response to copper ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "50.440435482492667", "identifiers": [{"i": "GO:0036211", "l": "protein modification process", "d": ["The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000754", "l": "adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion", "d": ["In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048821", "l": "erythrocyte development", "d": ["The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061973", "l": "membrane bone morphogenesis", "d": ["The process in which bone which forms deep in the organism are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1905345", "l": "protein localization to cleavage furrow", "d": ["A process in which a protein is transported to, or maintained in, a location within a cleavage furrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0045116", "l": "protein neddylation", "d": ["Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010732", "l": "regulation of protein glutathionylation", "d": ["Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071506", "l": "cellular response to mycophenolic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0006904", "l": "vesicle docking involved in exocytosis", "d": ["The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061379", "l": "inferior colliculus development", "d": ["The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000964", "l": "negative regulation of cellooligosaccharide catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032081", "l": "negative regulation of type II site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016479", "l": "negative regulation of transcription by RNA polymerase I", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.969478998631025", "identifiers": [{"i": "GO:0014055", "l": "acetylcholine secretion, neurotransmission", "d": ["The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0010332", "l": "response to gamma radiation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905661", "l": "regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120012", "l": "intermembrane sphingolipid transfer", "d": ["The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019468", "l": "nopaline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002571", "l": "somatic diversification of T cell receptor genes by N region addition", "d": ["The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035130", "l": "post-embryonic pectoral fin morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045743", "l": "positive regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019728", "l": "peptidyl-allysine oxidation to 2-aminoadipic acid", "d": ["The oxidation of allysine to 2-aminoadipic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901432", "l": "negative regulation of response to cycloalkane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0050942", "l": "positive regulation of pigment cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of pigment cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051561", "l": "positive regulation of mitochondrial calcium ion concentration", "d": ["Any process that increases the concentration of calcium ions in mitochondria."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900751", "l": "4-(trimethylammonio)butanoate transport", "d": ["The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904775", "l": "positive regulation of ubiquinone biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042820", "l": "vitamin B6 catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046031", "l": "ADP metabolic process", "d": ["The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033537", "l": "ajugose biosynthetic process using galactinol:raffinose galactosyltransferase", "d": ["The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075720", "l": "establishment of episomal latency", "d": ["A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0052008", "l": "disruption by symbiont of host cellular component", "d": ["The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0001774", "l": "microglial cell activation", "d": ["The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042682", "l": "regulation of compound eye cone cell fate specification", "d": ["Any process that mediates the specification of a cell into a compound eye cone cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031036", "l": "myosin II filament assembly", "d": ["The formation of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003400", "l": "regulation of COPII vesicle coating", "d": ["Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046704", "l": "CDP metabolic process", "d": ["The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018938", "l": "2-nitropropane metabolic process", "d": ["The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0070599", "l": "fungal-type cell wall (1->3)-alpha-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060757", "l": "adult foraging behavior", "d": ["Behavior by which an adult locates food."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080159", "l": "zygote elongation", "d": ["The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045315", "l": "positive regulation of compound eye photoreceptor development", "d": ["Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048386", "l": "positive regulation of retinoic acid receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060501", "l": "positive regulation of epithelial cell proliferation involved in lung morphogenesis", "d": ["Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007157", "l": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "d": ["The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140279", "l": "regulation of mitotic division septum assembly", "d": ["Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:2000762", "l": "regulation of phenylpropanoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016112", "l": "polyterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0017001", "l": "antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034378", "l": "chylomicron assembly", "d": ["The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060578", "l": "superior vena cava morphogenesis", "d": ["The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904249", "l": "negative regulation of age-related resistance", "d": ["Any process that stops, prevents or reduces the extent of age-related resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0034032", "l": "purine nucleoside bisphosphate metabolic process", "d": ["The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000552", "l": "negative regulation of T-helper 2 cell cytokine production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0033559", "l": "unsaturated fatty acid metabolic process", "d": ["The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030205", "l": "dermatan sulfate metabolic process", "d": ["The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070220", "l": "aerobic sulfur oxidation", "d": ["A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071660", "l": "positive regulation of IP-10 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of IP-10."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0055013", "l": "cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.665996090425516", "identifiers": [{"i": "GO:0006897", "l": "endocytosis", "d": ["A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007497", "l": "posterior midgut development", "d": ["The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106129", "l": "positive regulation of store-operated calcium entry", "d": ["Any process that activates or increases the frequency, rate or extent of store-operated calcium entry."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0055058", "l": "symmetric neuroblast division", "d": ["The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0051081", "l": "nuclear membrane disassembly", "d": ["The controlled breakdown of the nuclear membranes, for example during cellular division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045343", "l": "regulation of MHC class I biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035232", "l": "germ cell attraction", "d": ["The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0043417", "l": "negative regulation of skeletal muscle tissue regeneration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070416", "l": "trehalose metabolism in response to water deprivation", "d": ["The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0032328", "l": "alanine transport", "d": ["The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0150107", "l": "positive regulation of protein localization to cell-cell junction", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006642", "l": "triglyceride mobilization", "d": ["The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021940", "l": "positive regulation of cerebellar granule cell precursor proliferation", "d": ["The process that activates or increases the rate or extent of granule cell precursor proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.752564210074205", "identifiers": [{"i": "GO:0046395", "l": "carboxylic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031457", "l": "glycine betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903745", "l": "negative regulation of pharyngeal pumping", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0070943", "l": "neutrophil-mediated killing of symbiont cell", "d": ["The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0051327", "l": "meiotic M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1905319", "l": "mesenchymal stem cell migration", "d": ["The orderly movement of a mesenchymal stem cell from one site to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072285", "l": "mesenchymal to epithelial transition involved in metanephric renal vesicle formation", "d": ["A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000862", "l": "negative regulation of estrogen secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032691", "l": "negative regulation of interleukin-1 beta production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032919", "l": "spermine acetylation", "d": ["The modification of spermine by addition of acetyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:1905214", "l": "regulation of RNA binding", "d": ["Any process that modulates the frequency, rate or extent of RNA binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900865", "l": "chloroplast RNA modification", "d": ["Any RNA modification that takes place in chloroplast."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043521", "l": "regulation of myosin II filament disassembly", "d": ["Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019634", "l": "organic phosphonate metabolic process", "d": ["The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045071", "l": "negative regulation of viral genome replication", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "52.381699370032315", "identifiers": [{"i": "GO:0006508", "l": "proteolysis", "d": ["The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0019312", "l": "L-sorbose metabolic process", "d": ["The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. 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Isomerase is the systematic name for any enzyme of EC class 5."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.969909400061496", "identifiers": [{"i": "GO:0120252", "l": "hydrocarbon metabolic process", "d": ["The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071266", "l": "'de novo' L-methionine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0072033", "l": "renal vesicle formation", "d": ["The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. 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This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0055022", "l": "negative regulation of cardiac muscle tissue growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002242", "l": "defense response to parasitic plant", "d": ["Reactions triggered in response to the presence of a parasitic plant that act to protect an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036113", "l": "very long-chain fatty-acyl-CoA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035378", "l": "carbon dioxide transmembrane transport", "d": ["The process in which carbon dioxide (CO2) is transported across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904556", "l": "L-tryptophan transmembrane transport", "d": ["The directed movement of L-tryptophan across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901428", "l": "regulation of syringal lignin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090328", "l": "regulation of olfactory learning", "d": ["Any process that modulates the rate, frequency, or extent of olfactory learning. 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The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046831", "l": "regulation of RNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052183", "l": "disruption of symbiont cellular component", "d": ["The process in which a host organism destabilizes a cellular component of a symbiont organism. 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A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035754", "l": "B cell chemotaxis", "d": ["The directed movement of a B cell guided by a specific chemical concentration gradient. 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Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900689", "l": "regulation of gliotoxin biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0060082", "l": "eye blink reflex", "d": ["The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0032627", "l": "interleukin-23 production", "d": ["The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:1903051", "l": "negative regulation of proteolysis involved in protein catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033070", "l": "ansamycin biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007318", "l": "pole plasm protein localization", "d": ["Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0031398", "l": "positive regulation of protein ubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0036177", "l": "filamentous growth of a population of unicellular organisms in response to pH", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901390", "l": "positive regulation of transforming growth factor beta activation", "d": ["Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014830", "l": "arteriole smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150022", "l": "apical dendrite development", "d": ["The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000931", "l": "negative regulation of cellobiose metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030394", "l": "fructoseglycine metabolic process", "d": ["The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.751739371353352", "identifiers": [{"i": "GO:0008652", "l": "amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905884", "l": "negative regulation of triglyceride transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900408", "l": "negative regulation of cellular response to oxidative stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046713", "l": "borate transport", "d": ["The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0009626", "l": "plant-type hypersensitive response", "d": ["The rapid, localized death of plant cells in response to invasion by a pathogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.914165308394445", "identifiers": [{"i": "GO:0043065", "l": "positive regulation of apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903536", "l": "positive regulation of lactose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060133", "l": "somatotropin secreting cell development", "d": ["The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000908", "l": "positive regulation of glucomannan catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042474", "l": "middle ear morphogenesis", "d": ["The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002869", "l": "positive regulation of B cell deletion", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell deletion."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0006637", "l": "acyl-CoA metabolic process", "d": ["The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001029", "l": "regulation of cellular glucuronidation", "d": ["Any process that modulates the frequency, rate or extent of cellular glucuronidation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140532", "l": "negative regulation of osmosensory signaling MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901369", "l": "cyclic 2,3-bisphospho-D-glycerate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140919", "l": "thermomorphogenesis", "d": ["The suite of morphological and architectural changes in an organism induced by high ambient temperatures, below the heat-stress range."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002644", "l": "negative regulation of tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045773", "l": "positive regulation of axon extension", "d": ["Any process that activates or increases the frequency, rate or extent of axon extension."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0039695", "l": "DNA-templated viral transcription", "d": ["A transcription process that uses a viral DNA as a template."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0098902", "l": "regulation of membrane depolarization during action potential", "d": ["Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072035", "l": "pre-tubular aggregate formation", "d": ["The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090666", "l": "scaRNA localization to Cajal body", "d": ["A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003240", "l": "conus arteriosus formation", "d": ["The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001288", "l": "positive regulation of caveolin-mediated endocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0006635", "l": "fatty acid beta-oxidation", "d": ["A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010819", "l": "regulation of T cell chemotaxis", "d": ["Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903388", "l": "regulation of synaptic vesicle uncoating", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048362", "l": "pedicel mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the flower stem."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.344066130060426", "identifiers": [{"i": "GO:0061024", "l": "membrane organization", "d": ["A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035739", "l": "CD4-positive, alpha-beta T cell proliferation", "d": ["The expansion of a CD4-positive, alpha-beta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0048538", "l": "thymus development", "d": ["The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015883", "l": "FAD transport", "d": ["The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0072347", "l": "response to anesthetic", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045804", "l": "negative regulation of eclosion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051975", "l": "lysine biosynthetic process via alpha-aminoadipate and saccharopine", "d": ["The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021753", "l": "superior salivary nucleus development", "d": ["The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044739", "l": "positive regulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0043060", "l": "meiotic metaphase I homologous chromosome alignment", "d": ["A cell cycle process whereby homlogous chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator) by the spindle machinery and centromere/kinetochore arrangement during meiosis I chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035984", "l": "cellular response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904081", "l": "positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901468", "l": "positive regulation of ferulate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of ferulate catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.988400485557229", "identifiers": [{"i": "GO:0060047", "l": "heart contraction", "d": ["The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044505", "l": "positive regulation of G protein-coupled receptor activity in another organism", "d": ["A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902046", "l": "positive regulation of Fas signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of Fas signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.124874125835319", "identifiers": [{"i": "GO:0099003", "l": "vesicle-mediated transport in synapse", "d": ["Any vesicle-mediated transport that occurs in a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036316", "l": "SREBP-SCAP complex retention in endoplasmic reticulum", "d": ["Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021767", "l": "mammillary body development", "d": ["The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902923", "l": "poly(3-hydroxyvalerate) biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090135", "l": "actin filament branching", "d": ["The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0038002", "l": "endocrine signaling", "d": ["The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0035220", "l": "wing disc development", "d": ["Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0031321", "l": "ascospore-type prospore assembly", "d": ["During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032693", "l": "negative regulation of interleukin-10 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075312", "l": "negative regulation of sporangium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0009080", "l": "pyruvate family amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901450", "l": "positive regulation of response to butan-1-ol", "d": ["Any process that activates or increases the frequency, rate or extent of response to butan-1-ol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019263", "l": "adamantanone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990539", "l": "fructose import across plasma membrane", "d": ["The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904877", "l": "positive regulation of DNA ligase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0030448", "l": "hyphal growth", "d": ["Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900175", "l": "regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "d": ["Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904378", "l": "maintenance of unfolded protein involved in ERAD pathway", "d": ["Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002350", "l": "peripheral B cell positive selection", "d": ["Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900265", "l": "regulation of substance P receptor binding", "d": ["Any process that modulates the frequency, rate or extent of substance P receptor binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0051665", "l": "membrane raft localization", "d": ["Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0071827", "l": "plasma lipoprotein particle organization", "d": ["A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0030299", "l": "intestinal cholesterol absorption", "d": ["Uptake of cholesterol into the blood by absorption from the small intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0050798", "l": "activated T cell proliferation", "d": ["The expansion of a T cell population following activation by an antigenic stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0032814", "l": "regulation of natural killer cell activation", "d": ["Any process that modulates the frequency, rate or extent of natural killer cell activation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003325", "l": "pancreatic PP cell development", "d": ["The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0055071", "l": "manganese ion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075269", "l": "positive regulation of aecium development", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0035967", "l": "cellular response to topologically incorrect protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1902883", "l": "negative regulation of response to oxidative stress", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905049", "l": "negative regulation of metallopeptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0044358", "l": "envenomation resulting in hemorrhagic damage in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003184", "l": "pulmonary valve morphogenesis", "d": ["The process in which the structure of the pulmonary valve is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031538", "l": "negative regulation of anthocyanin metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0035213", "l": "clypeo-labral disc development", "d": ["The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0019682", "l": "glyceraldehyde-3-phosphate metabolic process", "d": ["The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0006625", "l": "protein targeting to peroxisome", "d": ["The process of directing proteins towards the peroxisome, usually using signals contained within the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035074", "l": "pupation", "d": ["The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902637", "l": "neural crest cell differentiation involved in thymus development", "d": ["Any neural crest cell differentiation that is involved in thymus development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002160", "l": "desmosome maintenance", "d": ["The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0046176", "l": "aldonic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.683459462529498", "identifiers": [{"i": "GO:0008300", "l": "isoprenoid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903447", "l": "geraniol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of geraniol."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0010412", "l": "mannan metabolic process", "d": ["The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901031", "l": "regulation of response to reactive oxygen species", "d": ["Any process that modulates the frequency, rate or extent of response to reactive oxygen species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106394", "l": "negative regulation of palmitic acid catabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a palmitic acid catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.460341447702248", "identifiers": [{"i": "GO:0042886", "l": "amide transport", "d": ["The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045981", "l": "positive regulation of nucleotide metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901424", "l": "response to toluene", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060331", "l": "negative regulation of response to type II interferon", "d": ["Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075249", "l": "positive regulation of aeciospore formation", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010849", "l": "regulation of proton-transporting ATPase activity, rotational mechanism", "d": ["Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014063", "l": "negative regulation of serotonin secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0009648", "l": "photoperiodism", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0097050", "l": "type B pancreatic cell apoptotic process", "d": ["Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045114", "l": "beta 2 integrin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009624", "l": "response to nematode", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048918", "l": "posterior lateral line nerve development", "d": ["The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035733", "l": "hepatic stellate cell activation", "d": ["A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018082", "l": "peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine", "d": ["The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061504", "l": "cyclic threonylcarbamoyladenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035609", "l": "C-terminal protein deglutamylation", "d": ["The removal of a C-terminal, gene-encoded glutamate residue from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071224", "l": "cellular response to peptidoglycan", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060599", "l": "lateral sprouting involved in mammary gland duct morphogenesis", "d": ["The process in which a branch forms along the side of a mammary duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:1905897", "l": "regulation of response to endoplasmic reticulum stress", "d": ["Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006209", "l": "cytosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905084", "l": "positive regulation of mitochondrial translational elongation", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071474", "l": "cellular hyperosmotic response", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0018194", "l": "peptidyl-alanine modification", "d": ["The modification of peptidyl-alanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0016203", "l": "muscle attachment", "d": ["The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990484", "l": "aerobic lactate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072520", "l": "seminiferous tubule development", "d": ["The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0051256", "l": "mitotic spindle midzone assembly", "d": ["The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071505", "l": "response to mycophenolic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0045881", "l": "positive regulation of sporulation resulting in formation of a cellular spore", "d": ["Any process that activates or increases the frequency, rate or extent of sporulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904778", "l": "positive regulation of protein localization to cell cortex", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.404261441961971", "identifiers": [{"i": "GO:0001817", "l": "regulation of cytokine production", "d": ["Any process that modulates the frequency, rate, or extent of production of a cytokine."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.071635092918072", "identifiers": [{"i": "GO:0018198", "l": "peptidyl-cysteine modification", "d": ["The modification of peptidyl-cysteine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075002", "l": "adhesion of symbiont germination tube to host", "d": ["The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0045581", "l": "negative regulation of T cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031031", "l": "positive regulation of septation initiation signaling", "d": ["Any process that activates or increases the frequency, rate or extent of septation initiation signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002023", "l": "reduction of food intake in response to dietary excess", "d": ["An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097102", "l": "endothelial tip cell fate specification", "d": ["The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0018209", "l": "peptidyl-serine modification", "d": ["The modification of peptidyl-serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010275", "l": "NAD(P)H dehydrogenase complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035878", "l": "nail development", "d": ["The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014908", "l": "myotube differentiation involved in skeletal muscle regeneration", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046667", "l": "compound eye retinal cell programmed cell death", "d": ["Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium."]}]} {"type": "biolink:BiologicalProcess", "ic": "59.880629464838911", "identifiers": [{"i": "GO:0043414", "l": "macromolecule methylation", "d": ["The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903253", "l": "hercynylcysteine sulfoxide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002188", "l": "translation reinitiation", "d": ["A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900893", "l": "regulation of tridecane metabolic process", "d": ["Any process that modulates the frequency, rate or extent of tridecane metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0062169", "l": "regulation of plus-end directed microtubule sliding", "d": ["Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002191", "l": "cap-dependent translational initiation", "d": ["The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070452", "l": "positive regulation of ergosterol biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0007007", "l": "inner mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048354", "l": "mucilage biosynthetic process involved in seed coat development", "d": ["The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0048832", "l": "specification of plant organ number", "d": ["The regionalization process that modulates the quantity of a particular type of plant organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006422", "l": "aspartyl-tRNA aminoacylation", "d": ["The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0080155", "l": "regulation of double fertilization forming a zygote and endosperm", "d": ["Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048826", "l": "cotyledon morphogenesis", "d": ["The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000828", "l": "regulation of parathyroid hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of parathyroid hormone secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0052038", "l": "modulation by symbiont of host intracellular transport", "d": ["Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903045", "l": "neural crest cell migration involved in sympathetic nervous system development", "d": ["Any neural crest cell migration that is involved in sympathetic nervous system development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032049", "l": "cardiolipin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009386", "l": "translational attenuation", "d": ["Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071720", "l": "sodium-independent prostaglandin transport", "d": ["The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019615", "l": "catechol catabolic process, ortho-cleavage", "d": ["The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903337", "l": "positive regulation of vacuolar transport", "d": ["Any process that activates or increases the frequency, rate or extent of vacuolar transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0032042", "l": "mitochondrial DNA metabolic process", "d": ["The chemical reactions and pathways involving mitochondrial DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002497", "l": "proteasomal proteolysis associated with antigen processing and presentation", "d": ["The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021855", "l": "hypothalamus cell migration", "d": ["The directed movement of a cell into the hypothalamus region of the forebrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0051260", "l": "protein homooligomerization", "d": ["The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.401997675337611", "identifiers": [{"i": "GO:0008213", "l": "protein alkylation", "d": ["The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902066", "l": "regulation of cell wall pectin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018964", "l": "propylene metabolic process", "d": ["The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001090", "l": "maltotriulose transport", "d": ["The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015955", "l": "pyrimidine deoxyribonucleotide interconversion", "d": ["The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0000027", "l": "ribosomal large subunit assembly", "d": ["The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018284", "l": "iron incorporation into protein via tetrakis-L-cysteinyl iron", "d": ["The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003061", "l": "positive regulation of the force of heart contraction by norepinephrine", "d": ["The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000864", "l": "regulation of estradiol secretion", "d": ["Any process that modulates the frequency, rate or extent of estradiol secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000391", "l": "positive regulation of neutrophil extravasation", "d": ["Any process that activates or increases the frequency, rate or extent of neutrophil extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071504", "l": "cellular response to heparin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0002067", "l": "glandular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071218", "l": "cellular response to misfolded protein", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006079", "l": "(1->6)-beta-D-glucan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018133", "l": "peptide cross-linking via L-cysteine oxazolinecarboxylic acid", "d": ["The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.869303025598512", "identifiers": [{"i": "GO:0006692", "l": "prostanoid metabolic process", "d": ["The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0030979", "l": "alpha-glucan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051970", "l": "negative regulation of transmission of nerve impulse", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019086", "l": "late viral transcription", "d": ["The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061949", "l": "regulation of premature acrosome loss", "d": ["Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0032409", "l": "regulation of transporter activity", "d": ["Any process that modulates the activity of a transporter."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905484", "l": "negative regulation of motor neuron migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032294", "l": "peripheral nervous system non-myelinated axon ensheathment", "d": ["The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0018195", "l": "peptidyl-arginine modification", "d": ["The modification of peptidyl-arginine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042679", "l": "compound eye cone cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060829", "l": "negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation", "d": ["Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0071677", "l": "positive regulation of mononuclear cell migration", "d": ["Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019750", "l": "chloroplast localization", "d": ["Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.989777303936307", "identifiers": [{"i": "GO:0010927", "l": "cellular component assembly involved in morphogenesis", "d": ["The cellular component assembly that is part of the initial shaping of the component during its developmental progression."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031367", "l": "N-terminal peptidyl-glutamine deamination", "d": ["The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0009956", "l": "radial pattern formation", "d": ["The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.637244699369631", "identifiers": [{"i": "GO:0002262", "l": "myeloid cell homeostasis", "d": ["The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990211", "l": "positive regulation by symbiont of jasmonic acid levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050972", "l": "detection of mechanical stimulus involved in echolocation", "d": ["The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075258", "l": "negative regulation of teliospore formation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0050806", "l": "positive regulation of synaptic transmission", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0035290", "l": "trunk segmentation", "d": ["Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070512", "l": "positive regulation of histone H4-K20 methylation", "d": ["Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006204", "l": "IMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904791", "l": "negative regulation of shelterin complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036078", "l": "minus-end specific microtubule depolymerization", "d": ["The removal of tubulin heterodimers from the minus end of a microtubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903614", "l": "negative regulation of protein tyrosine phosphatase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0002063", "l": "chondrocyte development", "d": ["The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141031", "l": "perturbation by symbiont of host actin cytoskeleton via actin crosslinking", "d": ["The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by actin crosslinking the host actin filaments. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "68.149273381153577", "identifiers": [{"i": "GO:1901136", "l": "carbohydrate derivative catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070184", "l": "mitochondrial tyrosyl-tRNA aminoacylation", "d": ["The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0098910", "l": "regulation of atrial cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0001408", "l": "guanine nucleotide transport", "d": ["The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031118", "l": "rRNA pseudouridine synthesis", "d": ["The intramolecular conversion of uridine to pseudouridine in an rRNA molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010804", "l": "negative regulation of tumor necrosis factor-mediated signaling pathway", "d": ["Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062132", "l": "regulation of L-glutamine biosynthetic process", "d": ["Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000906", "l": "positive regulation of starch metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of starch metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0003211", "l": "cardiac ventricle formation", "d": ["The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006648", "l": "dihydrosphingosine-1-P pathway", "d": ["A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035231", "l": "cytoneme assembly", "d": ["Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033684", "l": "regulation of luteinizing hormone secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0010391", "l": "glucomannan metabolic process", "d": ["The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0002256", "l": "regulation of kinin cascade", "d": ["Any process that modulates the frequency, rate, or extent of the kinin cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901299", "l": "negative regulation of hydrogen peroxide-mediated programmed cell death", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902273", "l": "negative regulation of (R)-carnitine transmembrane transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905639", "l": "positive regulation of mitochondrial mRNA catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000270", "l": "negative regulation of fibroblast apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903890", "l": "positive regulation of plant epidermal cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046761", "l": "viral budding from plasma membrane", "d": ["A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0007288", "l": "sperm axoneme assembly", "d": ["The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010221", "l": "negative regulation of vernalization response", "d": ["Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0048145", "l": "regulation of fibroblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0007501", "l": "mesodermal cell fate specification", "d": ["The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904108", "l": "protein localization to ciliary inversin compartment", "d": ["A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021937", "l": "cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation", "d": ["The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:1901655", "l": "cellular response to ketone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021547", "l": "midbrain-hindbrain boundary initiation", "d": ["The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071631", "l": "mating pheromone secretion involved in positive regulation of conjugation with cellular fusion", "d": ["The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.006620567903539", "identifiers": [{"i": "GO:0014033", "l": "neural crest cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:1902107", "l": "positive regulation of leukocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0039687", "l": "viral DNA strand displacement replication", "d": ["A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050675", "l": "regulation of urothelial cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of urothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0042068", "l": "regulation of pteridine metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006038", "l": "cell wall chitin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061098", "l": "positive regulation of protein tyrosine kinase activity", "d": ["Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061903", "l": "positive regulation of 1-phosphatidylinositol-3-kinase activity", "d": ["Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000769", "l": "syncytium formation by mitosis without cytokinesis", "d": ["The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901735", "l": "(R)-mevalonic acid metabolic process", "d": ["The chemical reactions and pathways involving (R)-mevalonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0060464", "l": "lung lobe formation", "d": ["The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0002553", "l": "histamine secretion by mast cell", "d": ["The regulated release of histamine by a mast cell or group of mast cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000719", "l": "negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.079643100360357", "identifiers": [{"i": "GO:1902742", "l": "apoptotic process involved in development", "d": ["Any apoptotic process that is involved in anatomical structure development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061327", "l": "anterior Malpighian tubule development", "d": ["The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031364", "l": "N-terminal protein amino acid deamination, from side chain", "d": ["The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071035", "l": "nuclear polyadenylation-dependent rRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061278", "l": "epithelial cell migration involved in mesonephric nephron tubule morphogenesis", "d": ["The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045645", "l": "positive regulation of eosinophil differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of eosinophil differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902137", "l": "(-)-secoisolariciresinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0018885", "l": "carbon tetrachloride metabolic process", "d": ["The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070473", "l": "negative regulation of uterine smooth muscle contraction", "d": ["Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060025", "l": "regulation of synaptic activity", "d": ["Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1904448", "l": "regulation of aspartate secretion", "d": ["Any process that modulates the frequency, rate or extent of aspartate secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0050849", "l": "negative regulation of calcium-mediated signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046066", "l": "dGDP metabolic process", "d": ["The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120158", "l": "positive regulation of collagen catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0033241", "l": "regulation of amine catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1901522", "l": "positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus", "d": ["Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090108", "l": "positive regulation of high-density lipoprotein particle assembly", "d": ["Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021652", "l": "rhombomere 1 formation", "d": ["The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042424", "l": "catecholamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "48.259624429835732", "identifiers": [{"i": "GO:0043412", "l": "macromolecule modification", "d": ["The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0017190", "l": "N-terminal peptidyl-aspartic acid acetylation", "d": ["The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010113", "l": "negative regulation of systemic acquired resistance", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0055081", "l": "monoatomic anion homeostasis", "d": ["Any process involved in the maintenance of an internal steady state of monoatomic anions within an organism or cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042366", "l": "cobalamin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000839", "l": "positive regulation of androstenedione secretion", "d": ["Any process that activates or increases the frequency, rate or extent of androstenedione secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061563", "l": "trigeminal ganglion structural organization", "d": ["The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.953330836288131", "identifiers": [{"i": "GO:0060078", "l": "regulation of postsynaptic membrane potential", "d": ["Any process that modulates the potential difference across a post-synaptic membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071038", "l": "nuclear polyadenylation-dependent tRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0021843", "l": "substrate-independent telencephalic tangential interneuron migration", "d": ["The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1900561", "l": "dehydroaustinol metabolic process", "d": ["The chemical reactions and pathways involving dehydroaustinol."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036521", "l": "modulation by symbiont of host protein localization to phagocytic vesicle", "d": ["Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048281", "l": "inflorescence morphogenesis", "d": ["The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071355", "l": "cellular response to interleukin-9", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0090266", "l": "regulation of mitotic cell cycle spindle assembly checkpoint", "d": ["Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990486", "l": "anaerobic fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031203", "l": "post-translational protein targeting to membrane, docking", "d": ["The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007429", "l": "secondary branching, open tracheal system", "d": ["Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050903", "l": "leukocyte activation-dependent arrest", "d": ["The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902791", "l": "undecan-2-one biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of undecan-2-one."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021655", "l": "rhombomere 2 morphogenesis", "d": ["The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903773", "l": "negative regulation of viral budding via host ESCRT complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0045582", "l": "positive regulation of T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071046", "l": "nuclear polyadenylation-dependent ncRNA catabolic process", "d": ["The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002892", "l": "regulation of type II hypersensitivity", "d": ["Any process that modulates the frequency, rate, or extent of type II hypersensitivity."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0060897", "l": "neural plate regionalization", "d": ["The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043930", "l": "primary ovarian follicle growth involved in primary follicle stage", "d": ["Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018306", "l": "iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide", "d": ["The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0031122", "l": "cytoplasmic microtubule organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0055015", "l": "ventricular cardiac muscle cell development", "d": ["The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0075732", "l": "viral penetration into host nucleus", "d": ["The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061064", "l": "negative regulation of nematode larval development", "d": ["Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901281", "l": "fructoselysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of fructoselysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010957", "l": "negative regulation of vitamin D biosynthetic process", "d": ["Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.679416033527399", "identifiers": [{"i": "GO:0043603", "l": "amide metabolic process", "d": ["The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0006056", "l": "mannoprotein metabolic process", "d": ["The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098768", "l": "meiotic prometaphase I", "d": ["The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060340", "l": "positive regulation of type I interferon-mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035348", "l": "acetyl-CoA transmembrane transport", "d": ["The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0033474", "l": "indoleacetic acid conjugate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904222", "l": "positive regulation of serine C-palmitoyltransferase activity", "d": ["Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035026", "l": "leading edge cell differentiation", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061099", "l": "negative regulation of protein tyrosine kinase activity", "d": ["Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006848", "l": "pyruvate transport", "d": ["The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106046", "l": "guanine deglycation, glyoxal removal", "d": ["The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0043279", "l": "response to alkaloid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0040020", "l": "regulation of meiotic nuclear division", "d": ["Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0033344", "l": "cholesterol efflux", "d": ["The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010121", "l": "arginine catabolic process to proline via ornithine", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061256", "l": "mesonephric podocyte differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010690", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "34.868060516835875", "identifiers": [{"i": "GO:0050896", "l": "response to stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900523", "l": "positive regulation of response to amylopectin", "d": ["Any process that activates or increases the frequency, rate or extent of response to amylopectin."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0006458", "l": "'de novo' protein folding", "d": ["The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000466", "l": "negative regulation of glycogen (starch) synthase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060576", "l": "intestinal epithelial cell development", "d": ["The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045801", "l": "positive regulation of chitin-based cuticle tanning", "d": ["Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009423", "l": "chorismate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:1902653", "l": "secondary alcohol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of secondary alcohol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014859", "l": "negative regulation of skeletal muscle cell proliferation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0071718", "l": "sodium-independent icosanoid transport", "d": ["The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0002508", "l": "central tolerance induction", "d": ["Tolerance induction in the central lymphoid organs: the thymus and bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010523", "l": "negative regulation of calcium ion transport into cytosol", "d": ["Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902351", "l": "response to imidacloprid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002282", "l": "microglial cell activation involved in immune response", "d": ["The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031587", "l": "positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity", "d": ["Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.061101857006449", "identifiers": [{"i": "GO:0061008", "l": "hepaticobiliary system development", "d": ["The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.072061987060081", "identifiers": [{"i": "GO:0002775", "l": "antimicrobial peptide production", "d": ["The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034171", "l": "regulation of toll-like receptor 11 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002676", "l": "regulation of chronic inflammatory response", "d": ["Any process that modulates the frequency, rate, or extent of a chronic inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039646", "l": "perturbation by virus of host G0/G1 transition checkpoint", "d": ["A process in which a virus interferes with the normal execution of the host cell G0/G1 transition checkpoint."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072539", "l": "T-helper 17 cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0015755", "l": "fructose transmembrane transport", "d": ["The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0010053", "l": "root epidermal cell differentiation", "d": ["The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0061122", "l": "positive regulation of positive chemotaxis to cAMP", "d": ["Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052323", "l": "negative regulation of phytoalexin biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0072564", "l": "blood microparticle formation", "d": ["The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106164", "l": "positive regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002212", "l": "behavioral defense response to nematode", "d": ["A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048701", "l": "embryonic cranial skeleton morphogenesis", "d": ["The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0022021", "l": "caudal ganglionic eminence cell proliferation", "d": ["The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0097355", "l": "protein localization to heterochromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0062226", "l": "regulation of adult somatic muscle development", "d": ["Any process that modulates the rate, frequency or extent of adult somatic muscle development."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990737", "l": "response to manganese-induced endoplasmic reticulum stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048358", "l": "mucilage pectin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of the pectin component of mucilage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900875", "l": "heptadec-1-ene biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of heptadec-1-ene."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.236441532430682", "identifiers": [{"i": "GO:0022008", "l": "neurogenesis", "d": ["Generation of cells within the nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019087", "l": "transformation of host cell by virus", "d": ["A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072063", "l": "short descending thin limb development", "d": ["The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032361", "l": "pyridoxal phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902011", "l": "poly(ribitol phosphate) teichoic acid metabolic process", "d": ["The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0034627", "l": "'de novo' NAD biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060662", "l": "salivary gland cavitation", "d": ["The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0021954", "l": "central nervous system neuron development", "d": ["The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035837", "l": "ergot alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an ergot alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046215", "l": "siderophore catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097694", "l": "establishment of RNA localization to telomere", "d": ["The directed movement of RNA to a specific location in the telomeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019529", "l": "taurine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010816", "l": "calcitonin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043418", "l": "homocysteine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033532", "l": "stachyose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.246894609297499", "identifiers": [{"i": "GO:0009642", "l": "response to light intensity", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2001260", "l": "regulation of semaphorin-plexin signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007362", "l": "terminal region determination", "d": ["Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903996", "l": "negative regulation of non-membrane spanning protein tyrosine kinase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905663", "l": "positive regulation of telomerase RNA reverse transcriptase activity", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140648", "l": "positive regulation of cell cycle switching, mitotic to meiotic cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0048844", "l": "artery morphogenesis", "d": ["The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039579", "l": "suppression by virus of host ISG15-protein conjugation", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 conjugation to a susbtrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042003", "l": "masculinization of hermaphrodite soma", "d": ["Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097739", "l": "negative regulation of ferrichrome biosynthetic process in response to iron", "d": ["Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0021604", "l": "cranial nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072663", "l": "establishment of protein localization to peroxisome", "d": ["The directed movement of a protein to a specific location in a peroxisome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903182", "l": "regulation of SUMO transferase activity", "d": ["Any process that modulates the frequency, rate or extent of SUMO ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019860", "l": "uracil metabolic process", "d": ["The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901015", "l": "3alpha(S)-strictosidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033489", "l": "cholesterol biosynthetic process via desmosterol", "d": ["The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060186", "l": "outer ear emergence", "d": ["The growth of the outer ear."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990145", "l": "maintenance of translational fidelity", "d": ["Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046819", "l": "protein secretion by the type V secretion system", "d": ["The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901248", "l": "positive regulation of lung ciliated cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905273", "l": "positive regulation of proton-transporting ATP synthase activity, rotational mechanism", "d": ["Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046358", "l": "butyrate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031388", "l": "organic acid phosphorylation", "d": ["The process of introducing one or more phosphate groups into an organic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042126", "l": "nitrate metabolic process", "d": ["The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002109", "l": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)", "d": ["Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032114", "l": "regulation of glucose-6-phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0019985", "l": "translesion synthesis", "d": ["The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902146", "l": "positive regulation of response to cell cycle checkpoint signaling", "d": ["Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071586", "l": "CAAX-box protein processing", "d": ["The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0000957", "l": "mitochondrial RNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006217", "l": "deoxycytidine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:1901016", "l": "regulation of potassium ion transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003358", "l": "noradrenergic neuron development", "d": ["The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043029", "l": "T cell homeostasis", "d": ["The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000760", "l": "negative regulation of N-terminal peptidyl-lysine acetylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009209", "l": "pyrimidine ribonucleoside triphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.06015934163878", "identifiers": [{"i": "GO:0000281", "l": "mitotic cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0007144", "l": "female meiosis I", "d": ["The cell cycle process in which the first meiotic division occurs in the female germline."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901685", "l": "glutathione derivative metabolic process", "d": ["The chemical reactions and pathways involving glutathione derivative."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090078", "l": "smooth muscle derived foam cell differentiation", "d": ["The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098726", "l": "symmetric division of skeletal muscle satellite stem cell", "d": ["The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0016074", "l": "sno(s)RNA metabolic process", "d": ["The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.79108406015925", "identifiers": [{"i": "GO:0051302", "l": "regulation of cell division", "d": ["Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0035879", "l": "plasma membrane lactate transport", "d": ["The directed movement of lactate across a plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009722", "l": "detection of cytokinin stimulus", "d": ["The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090331", "l": "negative regulation of platelet aggregation", "d": ["Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071722", "l": "detoxification of arsenic-containing substance", "d": ["Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000969", "l": "tRNA exon ligation utilizing ATP as source of linkage phosphate", "d": ["A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900844", "l": "negative regulation of monodictyphenone biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0036216", "l": "cellular response to stem cell factor stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0001837", "l": "epithelial to mesenchymal transition", "d": ["A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901191", "l": "negative regulation of formation of translation initiation ternary complex", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032499", "l": "detection of peptidoglycan", "d": ["The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035582", "l": "sequestering of BMP in extracellular matrix", "d": ["Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046465", "l": "dolichyl diphosphate metabolic process", "d": ["The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0060306", "l": "regulation of membrane repolarization", "d": ["Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048833", "l": "specification of floral organ number", "d": ["Any process that modulates the number of floral organs formed in a floral whorl."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042070", "l": "maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification", "d": ["Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042458", "l": "nopaline catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0070570", "l": "regulation of neuron projection regeneration", "d": ["Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0110082", "l": "regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000320", "l": "negative regulation of T-helper 17 cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0045196", "l": "establishment or maintenance of neuroblast polarity", "d": ["Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.292849836240194", "identifiers": [{"i": "GO:1901615", "l": "organic hydroxy compound metabolic process", "d": ["The chemical reactions and pathways involving organic hydroxy compound."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010686", "l": "tetracyclic triterpenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0072710", "l": "response to hydroxyurea", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0045738", "l": "negative regulation of DNA repair", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0001885", "l": "endothelial cell development", "d": ["The progression of an endothelial cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0032465", "l": "regulation of cytokinesis", "d": ["Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099015", "l": "degradation of host chromosome by virus", "d": ["The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010713", "l": "negative regulation of collagen metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097195", "l": "pilomotor reflex", "d": ["The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905564", "l": "positive regulation of vascular endothelial cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032224", "l": "positive regulation of synaptic transmission, cholinergic", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0045733", "l": "acetate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0042795", "l": "snRNA transcription by RNA polymerase II", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015699", "l": "antimonite transport", "d": ["The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0014072", "l": "response to isoquinoline alkaloid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1904802", "l": "RITS complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a RITS complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021717", "l": "inferior olivary nucleus maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035911", "l": "descending aorta morphogenesis", "d": ["The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990813", "l": "meiotic centromeric cohesion protection in anaphase I", "d": ["The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I after cohesin is cleaved by separase along the arm regions."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.944915021140389", "identifiers": [{"i": "GO:0002637", "l": "regulation of immunoglobulin production", "d": ["Any process that modulates the frequency, rate, or extent of immunoglobulin production."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0090435", "l": "protein localization to nuclear envelope", "d": ["A process in which a protein is transported to, or maintained at, a location within a nuclear envelope."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032304", "l": "negative regulation of icosanoid secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0072575", "l": "epithelial cell proliferation involved in liver morphogenesis", "d": ["The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902613", "l": "negative regulation of anti-Mullerian hormone signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006447", "l": "regulation of translational initiation by iron", "d": ["Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062075", "l": "pollen aperture formation", "d": ["The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120151", "l": "positive regulation of mitotic actomyosin contractile ring disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030259", "l": "lipid glycosylation", "d": ["Covalent attachment of a glycosyl residue to a lipid molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048755", "l": "branching morphogenesis of a nerve", "d": ["The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106215", "l": "negative regulation of vesicle fusion with Golgi apparatus", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.621873111364579", "identifiers": [{"i": "GO:0044249", "l": "cellular biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048783", "l": "positive regulation of cyanophore differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of cyanophore differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000037", "l": "regulation of stomatal complex patterning", "d": ["Any process that modulates the frequency, rate or extent of stomatal complex patterning."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1904666", "l": "regulation of ubiquitin protein ligase activity", "d": ["Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.85341545293393", "identifiers": [{"i": "GO:0050962", "l": "detection of light stimulus involved in sensory perception", "d": ["The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002015", "l": "regulation of systemic arterial blood pressure by atrial baroreceptor feedback", "d": ["A process that controls blood pressure by sensing the amount of stretch occurring in the atria."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901131", "l": "kanamycin metabolic process", "d": ["The chemical reactions and pathways involving kanamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903617", "l": "positive regulation of mitotic cytokinesis, division site positioning", "d": ["Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044205", "l": "'de novo' UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033156", "l": "oligogalacturonide transport", "d": ["The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019056", "l": "modulation by virus of host transcription", "d": ["Any process in which a virus modulates the frequency, rate or extent of its host's transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001560", "l": "regulation of cell growth by extracellular stimulus", "d": ["Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036050", "l": "peptidyl-lysine succinylation", "d": ["The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:1901994", "l": "negative regulation of meiotic cell cycle phase transition", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032837", "l": "distributive segregation", "d": ["The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060035", "l": "notochord cell development", "d": ["The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035314", "l": "scab formation", "d": ["Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034402", "l": "recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex", "d": ["The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900964", "l": "positive regulation of methanophenazine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032113", "l": "regulation of carbohydrate phosphatase activity", "d": ["Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903746", "l": "positive regulation of pharyngeal pumping", "d": ["Any process that activates or increases the frequency, rate or extent of pharyngeal pumping."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0034644", "l": "cellular response to UV", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060679", "l": "trifid subdivision of terminal units involved in ureteric bud branching", "d": ["The process in which a ureteric bud splits into three units at its end."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090262", "l": "regulation of transcription-coupled nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035995", "l": "detection of muscle stretch", "d": ["The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0071479", "l": "cellular response to ionizing radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042370", "l": "thiamine diphosphate dephosphorylation", "d": ["The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1904385", "l": "cellular response to angiotensin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120183", "l": "positive regulation of focal adhesion disassembly", "d": ["Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902845", "l": "negative regulation of mitotic spindle elongation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904416", "l": "negative regulation of xenophagy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.435793006653626", "identifiers": [{"i": "GO:0140353", "l": "lipid export from cell", "d": ["The directed movement of a lipid from a cell, into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034297", "l": "oidium formation", "d": ["The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060941", "l": "epicardium-derived cardiac fibroblast cell fate commitment", "d": ["The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034421", "l": "post-translational protein acetylation", "d": ["The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036154", "l": "diacylglycerol acyl-chain remodeling", "d": ["Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0062208", "l": "positive regulation of pattern recognition receptor signaling pathway", "d": ["Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097321", "l": "cell growth mode switching, filamentous to budding", "d": ["The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090444", "l": "regulation of nematode larval development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051793", "l": "medium-chain fatty acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of 6 to 12 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1905268", "l": "negative regulation of chromatin organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902433", "l": "positive regulation of water channel activity involved in maintenance of lens transparency", "d": ["Any positive regulation of water channel activity that is involved in maintenance of lens transparency."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019648", "l": "formaldehyde assimilation via xylulose monophosphate cycle", "d": ["The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071337", "l": "negative regulation of hair follicle cell proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.659841615658792", "identifiers": [{"i": "GO:0007080", "l": "mitotic metaphase chromosome alignment", "d": ["A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042793", "l": "plastid transcription", "d": ["The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051203", "l": "peptidyl-aspartic acid reduction to form L-aspartyl aldehyde", "d": ["The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071299", "l": "cellular response to vitamin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901738", "l": "regulation of vitamin A metabolic process", "d": ["Any process that modulates the frequency, rate or extent of vitamin A metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903851", "l": "negative regulation of cristae formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045725", "l": "positive regulation of glycogen biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045586", "l": "regulation of gamma-delta T cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021906", "l": "hindbrain-spinal cord boundary formation", "d": ["The process whose specific outcome is the formation of the hindbrain-spinal cord boundary."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.712653754434029", "identifiers": [{"i": "GO:0033673", "l": "negative regulation of kinase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006211", "l": "5-methylcytosine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045887", "l": "positive regulation of synaptic assembly at neuromuscular junction", "d": ["Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044517", "l": "modulation of vasoactive intestinal polypeptide receptor activity in another organism", "d": ["The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070995", "l": "NADPH oxidation", "d": ["A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045228", "l": "slime layer polysaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001804", "l": "negative regulation of type III hypersensitivity", "d": ["Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0032241", "l": "positive regulation of nucleobase-containing compound transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0046263", "l": "nitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007505", "l": "adult fat body development", "d": ["The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905795", "l": "cellular response to puromycin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010929", "l": "positive regulation of auxin mediated signaling pathway", "d": ["Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0032053", "l": "ciliary basal body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090076", "l": "relaxation of skeletal muscle", "d": ["A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0045671", "l": "negative regulation of osteoclast differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990076", "l": "cell wall polysaccharide catabolic process involved in abscission", "d": ["Any cell wall polysaccharide catabolic process that is involved in abscission."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:2001055", "l": "positive regulation of mesenchymal cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0030682", "l": "mitigation of host defenses by symbiont", "d": ["A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0021534", "l": "cell proliferation in hindbrain", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.857431420584163", "identifiers": [{"i": "GO:0009070", "l": "serine family amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062123", "l": "regulation of linear element maturation", "d": ["Any process that modulates the rate, frequency or extent of linear element maturation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0098710", "l": "guanine import across plasma membrane", "d": ["The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0042148", "l": "strand invasion", "d": ["The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090064", "l": "activation of microtubule nucleation", "d": ["Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901140", "l": "p-coumaryl alcohol transport", "d": ["The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097715", "l": "cellular response to viscosity", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0003417", "l": "growth plate cartilage development", "d": ["The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035171", "l": "lamellocyte differentiation", "d": ["The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0021553", "l": "olfactory nerve development", "d": ["The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904553", "l": "negative regulation of chemotaxis to arachidonic acid", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0010923", "l": "negative regulation of phosphatase activity", "d": ["Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030982", "l": "adventurous gliding motility", "d": ["A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071497", "l": "cellular response to freezing", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0070602", "l": "regulation of centromeric sister chromatid cohesion", "d": ["Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901929", "l": "alpha-copaene metabolic process", "d": ["The chemical reactions and pathways involving alpha-copaene."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048652", "l": "polyphenic determination, influence by genetic factors", "d": ["The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099179", "l": "regulation of synaptic membrane adhesion", "d": ["Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0055003", "l": "cardiac myofibril assembly", "d": ["The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.488267285704651", "identifiers": [{"i": "GO:0046459", "l": "short-chain fatty acid metabolic process", "d": ["The chemical reactions and pathways involving a fatty acid with an aliphatic tail of less than 6 carbons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903609", "l": "negative regulation of inward rectifier potassium channel activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032458", "l": "slow endocytic recycling", "d": ["The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000322", "l": "regulation of glucocorticoid receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1901516", "l": "aspyridone A metabolic process", "d": ["The chemical reactions and pathways involving aspyridone A."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:2000289", "l": "regulation of photoreceptor cell axon guidance", "d": ["Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance."]}]} {"type": "biolink:BiologicalProcess", "ic": "70.673456348239", "identifiers": [{"i": "GO:0051258", "l": "protein polymerization", "d": ["The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903915", "l": "positive regulation of fusion of virus membrane with host plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "63.375784702783051", "identifiers": [{"i": "GO:0045935", "l": "positive regulation of nucleobase-containing compound metabolic process", "d": ["Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.849015605436421", "identifiers": [{"i": "GO:0070988", "l": "demethylation", "d": ["The process of removing one or more methyl groups from a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:2000121", "l": "regulation of removal of superoxide radicals", "d": ["Any process that modulates the frequency, rate or extent of removal of superoxide radicals."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903412", "l": "response to bile acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032716", "l": "negative regulation of interleukin-7 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021642", "l": "trochlear nerve formation", "d": ["The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140877", "l": "mevastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060344", "l": "liver trabecula formation", "d": ["The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071382", "l": "cellular response to prostaglandin I stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045756", "l": "positive regulation of initiation of acetate catabolic process by acetate", "d": ["Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141072", "l": "symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway", "d": ["A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0042311", "l": "vasodilation", "d": ["An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060671", "l": "epithelial cell differentiation involved in embryonic placenta development", "d": ["The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009185", "l": "ribonucleoside diphosphate metabolic process", "d": ["The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120112", "l": "UDP-glucose transmembrane transport into endoplasmic reticulum", "d": ["The directed movement of UDP-glucose from cytosol to endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021720", "l": "superior olivary nucleus formation", "d": ["The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003232", "l": "bulbus arteriosus development", "d": ["The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018913", "l": "anaerobic ethylbenzene metabolic process", "d": ["The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902345", "l": "positive regulation of maltose transport", "d": ["Any process that activates or increases the frequency, rate or extent of maltose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009831", "l": "plant-type cell wall modification involved in multidimensional cell growth", "d": ["The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051462", "l": "regulation of cortisol secretion", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0018199", "l": "peptidyl-glutamine modification", "d": ["The modification of peptidyl-glutamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.17194633000733", "identifiers": [{"i": "GO:0018201", "l": "peptidyl-glycine modification", "d": ["The modification of peptidyl-glycine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060927", "l": "cardiac pacemaker cell fate commitment", "d": ["The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018245", "l": "protein O-linked glycosylation via tyrosine", "d": ["The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0140405", "l": "spindle pole body-led chromosome movement during mitotic interphase", "d": ["A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903515", "l": "calcium ion transport from cytosol to endoplasmic reticulum", "d": ["The directed movement of calcium ion from cytosol to endoplasmic reticulum."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021833", "l": "cell-matrix adhesion involved in tangential migration using cell-cell interactions", "d": ["The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904592", "l": "positive regulation of protein refolding", "d": ["Any process that activates or increases the frequency, rate or extent of protein refolding."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900296", "l": "positive regulation of heptasaccharide transport", "d": ["Any process that activates or increases the frequency, rate or extent of heptasaccharide transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0048845", "l": "venous blood vessel morphogenesis", "d": ["The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900321", "l": "regulation of maltotetraose transport", "d": ["Any process that modulates the frequency, rate or extent of maltotetraose transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050696", "l": "trichloroethylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1900271", "l": "regulation of long-term synaptic potentiation", "d": ["Any process that modulates the frequency, rate or extent of long-term synaptic potentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070073", "l": "clustering of voltage-gated calcium channels", "d": ["The process in which voltage-gated calcium channels become localized together in high densities."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.989777303936307", "identifiers": [{"i": "GO:0022898", "l": "regulation of transmembrane transporter activity", "d": ["Any process that modulates the frequency, rate or extent of transmembrane transporter activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0045754", "l": "positive regulation of acetate catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032922", "l": "circadian regulation of gene expression", "d": ["Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0046854", "l": "phosphatidylinositol phosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070593", "l": "dendrite self-avoidance", "d": ["The process in which dendrites recognize and avoid contact with sister dendrites from the same cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046439", "l": "L-cysteine metabolic process", "d": ["The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903080", "l": "regulation of C-C chemokine receptor CCR7 signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0043039", "l": "tRNA aminoacylation", "d": ["The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0009107", "l": "lipoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0019323", "l": "pentose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071400", "l": "cellular response to oleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046091", "l": "deoxyadenosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0003151", "l": "outflow tract morphogenesis", "d": ["The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902661", "l": "positive regulation of glucose mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1901027", "l": "dextrin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dextrin."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046401", "l": "lipopolysaccharide core region metabolic process", "d": ["The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010205", "l": "photoinhibition", "d": ["The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140891", "l": "tRNA-derived regulatory ncRNA processing", "d": ["A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060959", "l": "cardiac neuron development", "d": ["The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0015826", "l": "threonine transport", "d": ["The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050859", "l": "negative regulation of B cell receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021992", "l": "cell proliferation involved in neural plate elongation", "d": ["The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046182", "l": "L-idonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090166", "l": "Golgi disassembly", "d": ["A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0034239", "l": "regulation of macrophage fusion", "d": ["Any process that modulates the frequency, rate or extent of macrophage fusion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007175", "l": "negative regulation of epidermal growth factor-activated receptor activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003245", "l": "cardiac muscle tissue growth involved in heart morphogenesis", "d": ["The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900655", "l": "regulation of diorcinol biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003367", "l": "cell-cell adhesion involved in ameboidal cell migration", "d": ["The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098943", "l": "neurotransmitter receptor transport, postsynaptic endosome to lysosome", "d": ["The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0019460", "l": "glutamine catabolic process to fumarate", "d": ["The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0086021", "l": "SA node cell to atrial cardiac muscle cell communication by electrical coupling", "d": ["The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900972", "l": "negative regulation of sarcinapterin biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019339", "l": "parathion catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061451", "l": "retrotrapezoid nucleus development", "d": ["The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900019", "l": "regulation of protein kinase C activity", "d": ["Any process that modulates the frequency, rate or extent of protein kinase C activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0071816", "l": "tail-anchored membrane protein insertion into ER membrane", "d": ["A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010798", "l": "regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism", "d": ["Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006193", "l": "ITP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070407", "l": "oxidation-dependent protein catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0090045", "l": "positive regulation of deacetylase activity", "d": ["Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046172", "l": "octanol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1902751", "l": "positive regulation of cell cycle G2/M phase transition", "d": ["Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021542", "l": "dentate gyrus development", "d": ["The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014872", "l": "myoblast division", "d": ["The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060736", "l": "prostate gland growth", "d": ["The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0000054", "l": "ribosomal subunit export from nucleus", "d": ["The directed movement of a ribosomal subunit from the nucleus into the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0021840", "l": "directional guidance of interneurons involved in migration from the subpallium to the cortex", "d": ["The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0009221", "l": "pyrimidine deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902874", "l": "positive regulation of horizontal cell localization", "d": ["Any process that activates or increases the frequency, rate or extent of horizontal cell localization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018014", "l": "N-terminal peptidyl-methionine methylation", "d": ["The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0006145", "l": "purine nucleobase catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.046396088509496", "identifiers": [{"i": "GO:0042181", "l": "ketone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0045477", "l": "regulation of nurse cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of nurse cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019497", "l": "hexachlorocyclohexane metabolic process", "d": ["The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0070314", "l": "G1 to G0 transition", "d": ["A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903450", "l": "regulation of G1 to G0 transition", "d": ["Any process that modulates the frequency, rate or extent of G1 to G0 transition."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0048848", "l": "neurohypophysis morphogenesis", "d": ["The process in which the anatomical structures of the neurohypophysis are generated and organized. 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For example, cell communication occurs among more than one cell, but occurs at the cellular level."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.58416670140862", "identifiers": [{"i": "GO:0043967", "l": "histone H4 acetylation", "d": ["The modification of histone H4 by the addition of an acetyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007139", "l": "meiotic telophase II", "d": ["The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0120262", "l": "negative regulation of heterochromatin organization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904151", "l": "positive regulation of microglial cell mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033303", "l": "quercetin O-glucoside biosynthetic process", "d": ["The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0021679", "l": "cerebellar molecular layer development", "d": ["The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019488", "l": "ribitol catabolic process to xylulose 5-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0009301", "l": "snRNA transcription", "d": ["The synthesis of small nuclear RNA (snRNA) from a DNA template."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990734", "l": "astral microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end."]}]} {"type": "biolink:BiologicalProcess", "ic": "58.06975249093302", "identifiers": [{"i": "GO:0120036", "l": "plasma membrane bounded cell projection organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902510", "l": "regulation of apoptotic DNA fragmentation", "d": ["Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010447", "l": "response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0003260", "l": "cardioblast migration", "d": ["The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.292849836240194", "identifiers": [{"i": "GO:0046717", "l": "acid secretion", "d": ["The controlled release of acid by a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015806", "l": "S-methylmethionine transport", "d": ["The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.73602946617558", "identifiers": [{"i": "GO:0044706", "l": "multi-multicellular organism process", "d": ["A multicellular organism process which involves another multicellular organism of the same or different species."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1903624", "l": "regulation of DNA catabolic process", "d": ["Any process that modulates the frequency, rate or extent of DNA catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010710", "l": "regulation of collagen catabolic process", "d": ["Any process that modulates the rate, frequency or extent of collagen catabolism. 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An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071658", "l": "regulation of IP-10 production", "d": ["Any process that modulates the frequency, rate, or extent of production of IP-10."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106165", "l": "negative regulation of exonucleolytic catabolism of deadenylated mRNA", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0033182", "l": "regulation of histone ubiquitination", "d": ["Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140668", "l": "positive regulation of oxytocin production", "d": ["Any process that activates or increases the frequency, rate or extent of production of oxytocin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0014902", "l": "myotube differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0019853", "l": "L-ascorbic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042856", "l": "eugenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052088", "l": "symbiont defense to host-produced jasmonic acid", "d": ["Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1990280", "l": "RNA localization to chromatin", "d": ["A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0002800", "l": "regulation of antifungal peptide secretion", "d": ["Any process that modulates the frequency, rate, or extent of antifungal peptide secretion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098001", "l": "receptor-mediated bacteriophage reversible attachment to host cell", "d": ["Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060468", "l": "prevention of polyspermy", "d": ["The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031131", "l": "reception of an inductive signal", "d": ["The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0002654", "l": "positive regulation of tolerance induction dependent upon immune response", "d": ["Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048352", "l": "paraxial mesoderm structural organization", "d": ["The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035628", "l": "cystic duct development", "d": ["The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.107231545810777", "identifiers": [{"i": "GO:0043367", "l": "CD4-positive, alpha-beta T cell differentiation", "d": ["The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070257", "l": "positive regulation of mucus secretion", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042042", "l": "tungsten incorporation into tungsten-molybdopterin complex", "d": ["The incorporation of tungsten into a tungsten-molybdopterin complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001927", "l": "exocyst assembly", "d": ["The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0061559", "l": "cranial ganglion morphogenesis", "d": ["The process in which the anatomical structure of a cranial ganglion is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905786", "l": "positive regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141014", "l": "ribosome hibernation", "d": ["A cellular process that results in the silencing of ribosomes in quiescent cells. Quiescence takes place when cells encounter unfavorable conditions and cease to grow in bacteria and yeast. It also takes place in some specialized cells in higher eukaryotes, such as eggs. Ribosomes in a hibernation state are kept silent via association with proteins with inhibitory and protective functions."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0051679", "l": "6-alpha-maltosylglucose metabolic process", "d": ["The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019278", "l": "UDP-N-acetylgalactosamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901712", "l": "positive regulation of homoserine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000981", "l": "negative regulation of inner ear receptor cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900280", "l": "negative regulation of CD4-positive, alpha-beta T cell costimulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0002182", "l": "cytoplasmic translational elongation", "d": ["The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903427", "l": "negative regulation of reactive oxygen species biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000346", "l": "negative regulation of hepatocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.96520244130248", "identifiers": [{"i": "GO:0009124", "l": "nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031446", "l": "regulation of fast-twitch skeletal muscle fiber contraction", "d": ["Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070884", "l": "regulation of calcineurin-NFAT signaling cascade", "d": ["Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019503", "l": "L-proline betaine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905611", "l": "negative regulation of mRNA cap binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901786", "l": "p-cresol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cresol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120177", "l": "negative regulation of torso signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070152", "l": "mitochondrial isoleucyl-tRNA aminoacylation", "d": ["The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0098963", "l": "dendritic transport of messenger ribonucleoprotein complex", "d": ["The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0003140", "l": "determination of left/right asymmetry in lateral mesoderm", "d": ["The establishment of the lateral mesoderm with respect to the left and right halves."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071221", "l": "cellular response to bacterial lipopeptide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0048095", "l": "female pigmentation", "d": ["Establishment of a pattern of pigment in females."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0021785", "l": "branchiomotor neuron axon guidance", "d": ["The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900142", "l": "negative regulation of oligodendrocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001695", "l": "histamine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0043461", "l": "proton-transporting ATP synthase complex assembly", "d": ["The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0046959", "l": "habituation", "d": ["A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.665996090425516", "identifiers": [{"i": "GO:0003015", "l": "heart process", "d": ["A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002904", "l": "positive regulation of B cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900097", "l": "positive regulation of dosage compensation by inactivation of X chromosome", "d": ["Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003406", "l": "retinal pigment epithelium development", "d": ["The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0015764", "l": "N-acetylglucosamine transport", "d": ["The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901129", "l": "gentamycin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of gentamycin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021673", "l": "rhombomere 7 formation", "d": ["The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0010394", "l": "homogalacturonan metabolic process", "d": ["The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0043052", "l": "thermotaxis", "d": ["The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002424", "l": "T cell mediated immune response to tumor cell", "d": ["An immune response mediated by a T cell triggered in response to the presence of a tumor cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009168", "l": "purine ribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:2000888", "l": "arabinoxylan-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an arabinoxylan."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0045047", "l": "protein targeting to ER", "d": ["The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061561", "l": "trigeminal ganglion formation", "d": ["The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0036180", "l": "filamentous growth of a population of unicellular organisms in response to biotic stimulus", "d": ["The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035123", "l": "embryonic dorsal fin morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061258", "l": "mesonephric podocyte cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010099", "l": "regulation of photomorphogenesis", "d": ["Any process that modulates the rate or extent of photomorphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0070784", "l": "regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141070", "l": "symbiont-mediated suppression of host MAPK signal transduction pathway", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a MAPK signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000812", "l": "regulation of barbed-end actin filament capping", "d": ["Any process that modulates the frequency, rate or extent of barbed-end actin filament capping."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904322", "l": "cellular response to forskolin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1990180", "l": "mitochondrial tRNA 3'-end processing", "d": ["The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0002911", "l": "regulation of lymphocyte anergy", "d": ["Any process that modulates the frequency, rate, or extent of lymphocyte anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010727", "l": "negative regulation of hydrogen peroxide metabolic process", "d": ["Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900515", "l": "regulation of xylose catabolic process to ethanol", "d": ["Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900372", "l": "negative regulation of purine nucleotide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.370703631459492", "identifiers": [{"i": "GO:0000723", "l": "telomere maintenance", "d": ["Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0034372", "l": "very-low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071869", "l": "response to catecholamine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0033533", "l": "verbascose metabolic process", "d": ["The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0019885", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900352", "l": "negative regulation of methanofuran biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051089", "l": "constitutive protein ectodomain proteolysis", "d": ["The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000634", "l": "regulation of primary miRNA processing", "d": ["Any process that modulates the frequency, rate or extent of primary microRNA processing."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0031179", "l": "peptide modification", "d": ["The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010601", "l": "positive regulation of auxin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0046900", "l": "tetrahydrofolylpolyglutamate metabolic process", "d": ["The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035127", "l": "post-embryonic limb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0031034", "l": "myosin filament assembly", "d": ["The aggregation, arrangement and bonding together of a filament composed of myosin molecules."]}]} {"type": "biolink:BiologicalProcess", "ic": "17.651431767433237", "identifiers": [{"i": "GO:0034641", "l": "cellular nitrogen compound metabolic process", "d": ["The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0046284", "l": "anthocyanin-containing compound catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051819", "l": "induction by symbiont of tumor or growth in host", "d": ["The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140528", "l": "bilobe structure assembly", "d": ["The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903912", "l": "negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:0051311", "l": "meiotic metaphase chromosome alignment", "d": ["A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:1902074", "l": "response to salt", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904405", "l": "cellular response to formaldehyde", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071461", "l": "cellular response to redox state", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0042431", "l": "indole metabolic process", "d": ["The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000119", "l": "negative regulation of sodium-dependent phosphate transport", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071066", "l": "detection of mechanical stimulus involved in sensory perception of wind", "d": ["The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0042438", "l": "melanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0010868", "l": "negative regulation of triglyceride biosynthetic process", "d": ["Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903449", "l": "androst-4-ene-3,17-dione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.076046914303362", "identifiers": [{"i": "GO:2001053", "l": "regulation of mesenchymal cell apoptotic process", "d": ["Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000492", "l": "box C/D snoRNP assembly", "d": ["The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0035627", "l": "ceramide transport", "d": ["The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.946107901282822", "identifiers": [{"i": "GO:0006790", "l": "sulfur compound metabolic process", "d": ["The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071234", "l": "cellular response to phenylalanine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.721563224321088", "identifiers": [{"i": "GO:0030437", "l": "ascospore formation", "d": ["The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110066", "l": "negative regulation of interphase mitotic telomere clustering", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900349", "l": "negative regulation of methane biosynthetic process from methylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009754", "l": "detection of jasmonic acid stimulus", "d": ["The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018886", "l": "anaerobic carbon tetrachloride metabolic process", "d": ["The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0035429", "l": "gluconate transmembrane transport", "d": ["The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042848", "l": "sorbose catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035519", "l": "protein K29-linked ubiquitination", "d": ["A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0035927", "l": "RNA import into mitochondrion", "d": ["The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.247621244257502", "identifiers": [{"i": "GO:0045622", "l": "regulation of T-helper cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of T-helper cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0090093", "l": "regulation of fungal-type cell wall beta-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.631918968397358", "identifiers": [{"i": "GO:1900376", "l": "regulation of secondary metabolite biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0050927", "l": "positive regulation of positive chemotaxis", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071661", "l": "regulation of granzyme B production", "d": ["Any process that modulates the frequency, rate, or extent of production of granzyme B."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061679", "l": "Entner-Doudoroff pathway through gluconate", "d": ["The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900823", "l": "negative regulation of ergot alkaloid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0006868", "l": "glutamine transport", "d": ["The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0032222", "l": "regulation of synaptic transmission, cholinergic", "d": ["Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000079", "l": "regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "45.423985067806818", "identifiers": [{"i": "GO:0042592", "l": "homeostatic process", "d": ["Any biological process involved in the maintenance of an internal steady state."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0006862", "l": "nucleotide transport", "d": ["The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071915", "l": "protein-lysine lysylation", "d": ["The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070583", "l": "spore membrane bending pathway", "d": ["The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044808", "l": "oncostatin M production", "d": ["The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900982", "l": "positive regulation of phenazine biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0150157", "l": "regulation of interleukin-34 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-34 production."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0061545", "l": "tyramine secretion", "d": ["The regulated release of a tyramine by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0021778", "l": "oligodendrocyte cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed."]}]} {"type": "biolink:BiologicalProcess", "ic": "71.602448984170266", "identifiers": [{"i": "GO:0046164", "l": "alcohol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0080036", "l": "regulation of cytokinin-activated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of cytokinin signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.519451917212066", "identifiers": [{"i": "GO:0032943", "l": "mononuclear cell proliferation", "d": ["The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000630", "l": "positive regulation of miRNA metabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of miRNA metabolic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905676", "l": "positive regulation of adaptive immune memory response", "d": ["Any process that activates or increases the frequency, rate or extent of adaptive immune memory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0002452", "l": "B cell receptor editing", "d": ["The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061442", "l": "cardiac muscle cell fate determination", "d": ["The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0110008", "l": "ncRNA deadenylation", "d": ["Shortening of the poly(A) tail of a nuclear-transcribed ncRNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0039696", "l": "RNA-templated viral transcription", "d": ["A transcription process that uses viral RNA as a template."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045882", "l": "negative regulation of sulfur utilization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900936", "l": "negative regulation of nonadec-1-ene biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090106", "l": "pancreatic E cell fate commitment", "d": ["The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042968", "l": "homoserine transport", "d": ["The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061335", "l": "cell growth involved in Malpighian tubule morphogenesis", "d": ["The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0006595", "l": "polyamine metabolic process", "d": ["The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007377", "l": "germ-band extension", "d": ["Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. 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Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0035904", "l": "aorta development", "d": ["The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000081", "l": "positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0072156", "l": "distal tubule morphogenesis", "d": ["The process in which the anatomical structures of a distal tubule are generated and organized. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0030648", "l": "aminoglycoside antibiotic biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902752", "l": "regulation of renal amino acid absorption", "d": ["Any process that modulates the frequency, rate or extent of renal amino acid absorption."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033521", "l": "phytyl diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0030326", "l": "embryonic limb morphogenesis", "d": ["The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0046686", "l": "response to cadmium ion", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0006290", "l": "pyrimidine dimer repair", "d": ["The repair of UV-induced T-T, C-T and C-C dimers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052653", "l": "3',5'-cyclic diguanylic acid metabolic process", "d": ["The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.281523396999802", "identifiers": [{"i": "GO:0048364", "l": "root development", "d": ["The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002600", "l": "positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib", "d": ["Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071693", "l": "protein transport within extracellular region", "d": ["The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0019747", "l": "regulation of isoprenoid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045038", "l": "protein import into chloroplast thylakoid membrane", "d": ["The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.240937671532407", "identifiers": [{"i": "GO:0044058", "l": "regulation of digestive system process", "d": ["Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015836", "l": "lipid-linked peptidoglycan transport", "d": ["The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046307", "l": "Z-phenylacetaldoxime biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050899", "l": "nitrile catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1901627", "l": "negative regulation of postsynaptic membrane organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120041", "l": "positive regulation of macrophage proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of macrophage proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0002092", "l": "positive regulation of receptor internalization", "d": ["Any process that activates or increases the frequency, rate or extent of receptor internalization."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080057", "l": "sepal vascular tissue pattern formation", "d": ["Vascular tissue pattern formation as it occurs in the sepal of vascular plants."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032957", "l": "inositol trisphosphate metabolic process", "d": ["The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901820", "l": "alpha-zeacarotene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006172", "l": "ADP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035742", "l": "activated CD8-positive, alpha-beta T cell proliferation", "d": ["The expansion of an activated CD8-positive, alpha-beta T cell population by cell division."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0060481", "l": "lobar bronchus epithelium development", "d": ["The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014834", "l": "skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration", "d": ["Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:1900121", "l": "negative regulation of receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097749", "l": "membrane tubulation", "d": ["A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009197", "l": "pyrimidine deoxyribonucleoside diphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061185", "l": "negative regulation of dermatome development", "d": ["Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0000920", "l": "septum digestion after cytokinesis", "d": ["The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006239", "l": "dCMP salvage", "d": ["Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.105493098994543", "identifiers": [{"i": "GO:0006040", "l": "amino sugar metabolic process", "d": ["The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050861", "l": "positive regulation of B cell receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120257", "l": "peptidyl-threonine acetylation", "d": ["The acetylation of peptidyl-threonine."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0071362", "l": "cellular response to ether", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.983353031950202", "identifiers": [{"i": "GO:0046649", "l": "lymphocyte activation", "d": ["A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0050968", "l": "detection of chemical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035025", "l": "positive regulation of Rho protein signal transduction", "d": ["Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990223", "l": "positive regulation by symbiont of cytokinin levels in host", "d": ["Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0097281", "l": "immune complex formation", "d": ["The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002735", "l": "positive regulation of myeloid dendritic cell cytokine production", "d": ["Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075606", "l": "transport of viral material towards nucleus", "d": ["The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0071404", "l": "cellular response to low-density lipoprotein particle stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051844", "l": "translocation of peptides or proteins into symbiont", "d": ["The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003216", "l": "cardiac left atrium formation", "d": ["The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106150", "l": "zearalenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043504", "l": "mitochondrial DNA repair", "d": ["The process of restoring mitochondrial DNA after damage."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001043", "l": "positive regulation of septum digestion after cytokinesis", "d": ["Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0001992", "l": "regulation of systemic arterial blood pressure by vasopressin", "d": ["The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072140", "l": "DCT cell development", "d": ["The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051138", "l": "positive regulation of NK T cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001315", "l": "UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905843", "l": "regulation of cellular response to gamma radiation", "d": ["Any process that modulates the frequency, rate or extent of cellular response to gamma radiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014860", "l": "neurotransmitter secretion involved in regulation of skeletal muscle contraction", "d": ["The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046506", "l": "sulfolipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0042866", "l": "pyruvate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032494", "l": "response to peptidoglycan", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.476395680690302", "identifiers": [{"i": "GO:0051273", "l": "beta-glucan metabolic process", "d": ["The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010786", "l": "clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting", "d": ["The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0097699", "l": "vascular endothelial cell response to fluid shear stress", "d": ["Any response to fluid shear stress in a vascular endothelial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0043134", "l": "regulation of hindgut contraction", "d": ["Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061625", "l": "glycolytic process through fructose-1-phosphate", "d": ["The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903856", "l": "regulation of cytokinin dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120213", "l": "regulation of histidine biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of histidine biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0071839", "l": "apoptotic process in bone marrow cell", "d": ["The apoptotic process in cells in the bone marrow."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1903566", "l": "positive regulation of protein localization to cilium", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0031145", "l": "anaphase-promoting complex-dependent catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0031052", "l": "programmed DNA elimination by chromosome breakage", "d": ["Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1905960", "l": "response to differentiation-inducing factor 2", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0003220", "l": "left ventricular cardiac muscle tissue morphogenesis", "d": ["The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "64.45299868619928", "identifiers": [{"i": "GO:0071168", "l": "protein localization to chromatin", "d": ["Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990256", "l": "signal clustering", "d": ["Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060661", "l": "submandibular salivary gland formation", "d": ["The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2001151", "l": "regulation of renal water transport", "d": ["Any process that modulates the frequency, rate or extent of renal water transport."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0060074", "l": "synapse maturation", "d": ["The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000172", "l": "regulation of branching morphogenesis of a nerve", "d": ["Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048479", "l": "style development", "d": ["The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044129", "l": "positive regulation of development of symbiont in host", "d": ["Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0070298", "l": "negative regulation of phosphorelay signal transduction system", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.900487657105927", "identifiers": [{"i": "GO:0002577", "l": "regulation of antigen processing and presentation", "d": ["Any process that modulates the frequency, rate, or extent of antigen processing and presentation."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1900425", "l": "negative regulation of defense response to bacterium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium."]}]} {"type": "biolink:BiologicalProcess", "ic": "55.665724989692023", "identifiers": [{"i": "GO:0007588", "l": "excretion", "d": ["The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061079", "l": "left horn of sinus venosus development", "d": ["The progression of the left horn of the sinus venosus from its initial formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903334", "l": "positive regulation of protein folding", "d": ["Any process that activates or increases the frequency, rate or extent of protein folding."]}]} {"type": "biolink:BiologicalProcess", "ic": "60.180458012661006", "identifiers": [{"i": "GO:0048880", "l": "sensory system development", "d": ["The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure."]}]} {"type": "biolink:BiologicalProcess", "ic": "66.835772872909402", "identifiers": [{"i": "GO:0042692", "l": "muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a muscle cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0040036", "l": "regulation of fibroblast growth factor receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010781", "l": "meiotic DNA double-strand break formation involved in meiotic gene conversion", "d": ["The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060676", "l": "ureteric bud formation", "d": ["The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.533129568500584", "identifiers": [{"i": "GO:0030003", "l": "intracellular monoatomic cation homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903753", "l": "negative regulation of p38MAPK cascade", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043289", "l": "apocarotenoid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901051", "l": "atropine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of atropine. Atropine is the racemic mixture of hyoscyamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0051943", "l": "positive regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "80.511444690059548", "identifiers": [{"i": "GO:0006448", "l": "regulation of translational elongation", "d": ["Any process that modulates the frequency, rate, extent or accuracy of translational elongation."]}]} {"type": "biolink:BiologicalProcess", "ic": "62.247993244310685", "identifiers": [{"i": "GO:0007589", "l": "body fluid secretion", "d": ["The controlled release of a fluid by a cell or tissue in an animal."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048376", "l": "positive regulation of lateral mesodermal cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900214", "l": "regulation of apoptotic process involved in metanephric collecting duct development", "d": ["Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1904105", "l": "positive regulation of convergent extension involved in gastrulation", "d": ["Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0019685", "l": "photosynthesis, dark reaction", "d": ["A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900889", "l": "positive regulation of pentadecane biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0048060", "l": "negative gravitaxis", "d": ["The directed movement of a motile cell or organism away from the source of gravity."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0060615", "l": "mammary gland bud formation", "d": ["The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0072205", "l": "metanephric collecting duct development", "d": ["The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0032799", "l": "low-density lipoprotein receptor particle metabolic process", "d": ["The chemical reactions and pathways involving low-density lipoprotein receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0036181", "l": "protein localization to linear element", "d": ["A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061130", "l": "pancreatic bud formation", "d": ["The morphogenetic process in which the foregut region specified to become the pancreas forms a bud."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003396", "l": "cell adhesion involved in amphid sensory organ dendrite retrograde extension", "d": ["The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:0018208", "l": "peptidyl-proline modification", "d": ["The modification of peptidyl-proline."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0018283", "l": "iron incorporation into metallo-sulfur cluster", "d": ["The incorporation of iron into a metallo-sulfur cluster."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001175", "l": "transcriptional start site selection at RNA polymerase III promoter", "d": ["Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044341", "l": "sodium-dependent phosphate transport", "d": ["The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060262", "l": "negative regulation of N-terminal protein palmitoylation", "d": ["Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0014912", "l": "negative regulation of smooth muscle cell migration", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0032650", "l": "regulation of interleukin-1 alpha production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production."]}]} {"type": "biolink:BiologicalProcess", "ic": "78.695011174409487", "identifiers": [{"i": "GO:0048243", "l": "norepinephrine secretion", "d": ["The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019091", "l": "mitochondrial lrRNA export from mitochondrion", "d": ["The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0071498", "l": "cellular response to fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1902572", "l": "negative regulation of serine-type peptidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900350", "l": "positive regulation of methane biosynthetic process from methylamine", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046929", "l": "negative regulation of neurotransmitter secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0061049", "l": "cell growth involved in cardiac muscle cell development", "d": ["The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0022606", "l": "establishment of proximal/distal cell polarity", "d": ["The specification and formation of the polarity of a cell along its proximal/distal axis."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.483555723501368", "identifiers": [{"i": "GO:0031424", "l": "keratinization", "d": ["The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000558", "l": "positive regulation of immunoglobulin production in mucosal tissue", "d": ["Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072761", "l": "cellular response to capsazepine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098002", "l": "receptor-mediated bacteriophage irreversible attachment to host cell", "d": ["The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097640", "l": "L-ornithine import across plasma membrane", "d": ["The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "49.784715741494104", "identifiers": [{"i": "GO:0031326", "l": "regulation of cellular biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060854", "l": "branching involved in lymph vessel morphogenesis", "d": ["The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048396", "l": "negative regulation of intermediate mesodermal cell fate determination", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination."]}]} {"type": "biolink:BiologicalProcess", "ic": "81.648881485605159", "identifiers": [{"i": "GO:0016925", "l": "protein sumoylation", "d": ["The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002459", "l": "adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010723", "l": "positive regulation of transcription from RNA polymerase II promoter in response to iron", "d": ["Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120218", "l": "host interaction involved in quorum sensing", "d": ["A quorum sensing process that is modulated by some interaction with a host cell or organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0120071", "l": "regulation of pyloric antrum smooth muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000238", "l": "regulation of tRNA export from nucleus", "d": ["Any process that modulates the frequency, rate or extent of tRNA export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0043524", "l": "negative regulation of neuron apoptotic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032150", "l": "ubiquinone biosynthetic process from chorismate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002348", "l": "central B cell positive selection", "d": ["Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031648", "l": "protein destabilization", "d": ["Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044527", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from H2S", "d": ["The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0036287", "l": "response to iloperidone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019353", "l": "protoporphyrinogen IX biosynthetic process from glutamate", "d": ["The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060983", "l": "epicardium-derived cardiac vascular smooth muscle cell differentiation", "d": ["The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048784", "l": "pigment biosynthetic process involved in pigment granule maturation", "d": ["The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0048850", "l": "hypophysis morphogenesis", "d": ["The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0071969", "l": "fungal-type cell wall (1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000356", "l": "regulation of kidney smooth muscle cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0031444", "l": "slow-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0061178", "l": "regulation of insulin secretion involved in cellular response to glucose stimulus", "d": ["Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0031069", "l": "hair follicle morphogenesis", "d": ["The process in which the anatomical structures of the hair follicle are generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "72.269651791985453", "identifiers": [{"i": "GO:0030048", "l": "actin filament-based movement", "d": ["Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905700", "l": "negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097533", "l": "cellular stress response to acid chemical", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0034465", "l": "response to carbon monoxide", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.976162571356099", "identifiers": [{"i": "GO:0015914", "l": "phospholipid transport", "d": ["The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester."]}]} {"type": "biolink:BiologicalProcess", "ic": "79.541110464886842", "identifiers": [{"i": "GO:0046247", "l": "terpene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051112", "l": "peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine", "d": ["The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine)."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0097639", "l": "L-lysine import across plasma membrane", "d": ["The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "76.46797986554256", "identifiers": [{"i": "GO:0044111", "l": "formation of structure involved in a symbiotic process", "d": ["The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0019299", "l": "rhamnose metabolic process", "d": ["The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019711", "l": "peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid", "d": ["The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090676", "l": "calcium ion transmembrane transport via low voltage-gated calcium channel", "d": ["A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.582339958156282", "identifiers": [{"i": "GO:0008285", "l": "negative regulation of cell population proliferation", "d": ["Any process that stops, prevents or reduces the rate or extent of cell proliferation."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902746", "l": "regulation of lens fiber cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of lens fiber cell differentiation."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0018973", "l": "trinitrotoluene metabolic process", "d": ["The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006181", "l": "dGMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000039", "l": "regulation of trichome morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of trichome morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001159", "l": "regulation of protein localization by the Cvt pathway", "d": ["Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007464", "l": "R3/R4 cell fate commitment", "d": ["The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.552982069901191", "identifiers": [{"i": "GO:0002363", "l": "alpha-beta T cell lineage commitment", "d": ["The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061616", "l": "glycolytic process from fructose through fructose-6-phosphate", "d": ["The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902958", "l": "positive regulation of mitochondrial electron transport, NADH to ubiquinone", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903621", "l": "protein localization to photoreceptor connecting cilium", "d": ["A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1903185", "l": "L-dopa biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-dopa."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:1901704", "l": "L-glutamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-glutamine."]}]} {"type": "biolink:BiologicalProcess", "ic": "54.809513488357567", "identifiers": [{"i": "GO:0072359", "l": "circulatory system development", "d": ["The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0075252", "l": "regulation of uredospore formation", "d": ["Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0075198", "l": "modulation of symbiont haustorium neck formation for entry into host", "d": ["Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0060951", "l": "neural crest-derived cardiac glial cell differentiation", "d": ["The process in which a neural crest cell acquires the specialized features of a glial cell of the heart."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000240", "l": "positive regulation of tRNA export from nucleus", "d": ["Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036198", "l": "dTMP salvage", "d": ["Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.128890093485552", "identifiers": [{"i": "GO:0009851", "l": "auxin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth."]}]} {"type": "biolink:BiologicalProcess", "ic": "61.49789709104158", "identifiers": [{"i": "GO:0002697", "l": "regulation of immune effector process", "d": ["Any process that modulates the frequency, rate, or extent of an immune effector process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032083", "l": "negative regulation of type IV site-specific deoxyribonuclease activity", "d": ["Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018296", "l": "protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine", "d": ["The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044523", "l": "envenomation resulting in damage of muscle extracellular matrix in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0035836", "l": "ergot alkaloid metabolic process", "d": ["The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060366", "l": "lambdoid suture morphogenesis", "d": ["The process in which the lambdoid suture is generated and organized."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:1901475", "l": "pyruvate transmembrane transport", "d": ["The directed movement of pyruvate across a membrane."]}]} {"type": "biolink:BiologicalProcess", "ic": "67.292420608345139", "identifiers": [{"i": "GO:0099177", "l": "regulation of trans-synaptic signaling", "d": ["Any process that modulates the frequency, rate or extent of trans-synaptic signaling."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:1900827", "l": "positive regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:1901607", "l": "alpha-amino acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of an alpha-amino acid."]}]} {"type": "biolink:BiologicalProcess", "ic": "65.891564071043305", "identifiers": [{"i": "GO:0051253", "l": "negative regulation of RNA metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061078", "l": "positive regulation of prostaglandin secretion involved in immune response", "d": ["Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0010885", "l": "regulation of cholesterol storage", "d": ["Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140159", "l": "borate export across plasma membrane", "d": ["The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033468", "l": "CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030805", "l": "regulation of cyclic nucleotide catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides."]}]} {"type": "biolink:BiologicalProcess", "ic": "77.271239091128209", "identifiers": [{"i": "GO:0016579", "l": "protein deubiquitination", "d": ["The removal of one or more ubiquitin groups from a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0044725", "l": "epigenetic programming in the zygotic pronuclei", "d": ["The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002933", "l": "lipid hydroxylation", "d": ["The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075526", "l": "cap snatching", "d": ["A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0070107", "l": "regulation of interleukin-27-mediated signaling pathway", "d": ["Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0000715", "l": "nucleotide-excision repair, DNA damage recognition", "d": ["The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0009298", "l": "GDP-mannose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:0097396", "l": "response to interleukin-17", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120237", "l": "terminal acetylenic compound biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0016926", "l": "protein desumoylation", "d": ["The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901346", "l": "negative regulation of vasculature development involved in avascular cornea development in camera-type eye", "d": ["Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye."]}]} {"type": "biolink:BiologicalProcess", "ic": "74.37742281270377", "identifiers": [{"i": "GO:0035303", "l": "regulation of dephosphorylation", "d": ["Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0046095", "l": "deoxyinosine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside."]}]} {"type": "biolink:BiologicalProcess", "ic": "84.75972595860604", "identifiers": [{"i": "GO:0046351", "l": "disaccharide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0061864", "l": "basement membrane constituent secretion", "d": ["The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell."]}]} {"type": "biolink:BiologicalProcess", "ic": "83.023198044254755", "identifiers": [{"i": "GO:1905133", "l": "negative regulation of meiotic chromosome separation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation."]}]} {"type": "biolink:BiologicalProcess", "ic": "75.26123597683771", "identifiers": [{"i": "GO:0045862", "l": "positive regulation of proteolysis", "d": ["Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0009228", "l": "thiamine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0018960", "l": "4-nitrophenol metabolic process", "d": ["The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904827", "l": "negative regulation of hydrogen sulfide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1903903", "l": "regulation of establishment of T cell polarity", "d": ["Any process that modulates the frequency, rate or extent of establishment of T cell polarity."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0019342", "l": "trypanothione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043972", "l": "histone H3-K23 acetylation", "d": ["The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone."]}]} {"type": "biolink:BiologicalProcess", "ic": "82.532694649739099", "identifiers": [{"i": "GO:0009553", "l": "embryo sac development", "d": ["The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:0014910", "l": "regulation of smooth muscle cell migration", "d": ["Any process that modulates the frequency, rate or extent of smooth muscle cell migration."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000542", "l": "negative regulation of gastrulation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0003198", "l": "epithelial to mesenchymal transition involved in endocardial cushion formation", "d": ["A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905028", "l": "negative regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009666", "l": "plastid outer membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid."]}]} {"type": "biolink:BiologicalProcess", "ic": "85.457082654197222", "identifiers": [{"i": "GO:1905269", "l": "positive regulation of chromatin organization", "d": ["Any process that activates or increases the frequency, rate or extent of chromatin organization."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:2000495", "l": "regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140484", "l": "5-aminolevulinic acid import across plasma membrane", "d": ["The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021646", "l": "vagus nerve formation", "d": ["The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1902893", "l": "regulation of miRNA transcription", "d": ["Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0020014", "l": "schizogony", "d": ["Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007285", "l": "primary spermatocyte growth", "d": ["The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905645", "l": "negative regulation of FACT complex assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902346", "l": "meiotic strand displacement involved in double-strand break repair via SDSA", "d": ["Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA)."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905011", "l": "transmembrane phosphate ion transport from cytosol to vacuole", "d": ["The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044651", "l": "adhesion of symbiont to host epithelial cell", "d": ["The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1905684", "l": "regulation of plasma membrane repair", "d": ["Any process that modulates the frequency, rate or extent of plasma membrane repair."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046867", "l": "carotenoid transport", "d": ["The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904017", "l": "cellular response to Thyroglobulin triiodothyronine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0001692", "l": "histamine metabolic process", "d": ["The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0001798", "l": "positive regulation of type IIa hypersensitivity", "d": ["Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0032379", "l": "positive regulation of intracellular lipid transport", "d": ["Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0015789", "l": "UDP-N-acetylgalactosamine transmembrane transport", "d": ["The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019480", "l": "L-alanine oxidation to pyruvate via D-alanine", "d": ["The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900457", "l": "regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway."]}]} {"type": "biolink:BiologicalProcess", "ic": "86.236661114203869", "identifiers": [{"i": "GO:0000320", "l": "re-entry into mitotic cell cycle", "d": ["The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state."]}]} {"type": "biolink:BiologicalProcess", "ic": "56.602212321893283", "identifiers": [{"i": "GO:0050879", "l": "multicellular organismal movement", "d": ["Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "69.133783595722377", "identifiers": [{"i": "GO:0002274", "l": "myeloid leukocyte activation", "d": ["A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0015734", "l": "taurine transport", "d": ["The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."]}]} {"type": "biolink:BiologicalProcess", "ic": "87.120474278337809", "identifiers": [{"i": "GO:0097017", "l": "renal protein absorption", "d": ["A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686)."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0042443", "l": "phenylethylamine metabolic process", "d": ["The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds."]}]} {"type": "biolink:BiologicalProcess", "ic": "90.82444074280258", "identifiers": [{"i": "GO:0140246", "l": "protein catabolic process at synapse", "d": ["The chemical reactions and pathways resulting in the breakdown of a protein at a synapse."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042185", "l": "m-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon."]}]} {"type": "biolink:BiologicalProcess", "ic": "88.140761698499901", "identifiers": [{"i": "GO:0046621", "l": "negative regulation of organ growth", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism."]}]} {"type": "biolink:BiologicalProcess", "ic": "73.011730055819953", "identifiers": [{"i": "GO:0014821", "l": "phasic smooth muscle contraction", "d": ["A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations."]}]} {"type": "biolink:BiologicalProcess", "ic": "95.41222037140129", "identifiers": [{"i": "GO:0006272", "l": "leading strand elongation", "d": ["The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905367", "l": "positive regulation of intralumenal vesicle formation", "d": ["Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043538", "l": "regulation of actin phosphorylation", "d": ["Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002669", "l": "positive regulation of T cell anergy", "d": ["Any process that activates or increases the frequency, rate, or extent of T cell anergy."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090333", "l": "regulation of stomatal closure", "d": ["Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange."]}]} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007475", "l": "apposition of dorsal and ventral imaginal disc-derived wing surfaces", "d": ["The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing."]}]} {"type": "biolink:BiologicalProcess", "ic": "89.347505587204751", "identifiers": [{"i": "GO:0072133", "l": "metanephric mesenchyme morphogenesis", "d": ["The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros."]}]} {"type": "biolink:BiologicalProcess", "ic": "92.728541327098611", "identifiers": [{"i": "GO:1900318", "l": "regulation of methane biosynthetic process from dimethylamine", "d": ["Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine."]}]}