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An example of this is found in Drosophila melanogaster."], "t": []}], "preferred_name": "follicle cell of egg chamber migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0099639", "l": "neurotransmitter receptor transport, endosome to plasma membrane", "d": ["The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles."], "t": []}], "preferred_name": "neurotransmitter receptor transport, endosome to plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0043012", "l": "regulation of fusion of sperm to egg plasma membrane", "d": ["Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane."], "t": []}], "preferred_name": "regulation of fusion of sperm to egg plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904191", "l": "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division", "d": ["Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division."], "t": []}], "preferred_name": "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0039665", "l": "permeabilization of host organelle membrane involved in viral entry into host cell", "d": ["Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. 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The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification."], "t": []}], "preferred_name": "phenylalanyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904876", "l": "negative regulation of DNA ligase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity."], "t": []}], "preferred_name": "negative regulation of DNA ligase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1904229", "l": "regulation of succinate dehydrogenase activity", "d": ["Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity."], "t": []}], "preferred_name": "regulation of succinate dehydrogenase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0034391", "l": "regulation of smooth muscle cell apoptotic process", "d": ["Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process."], "t": []}], "preferred_name": "regulation of smooth muscle cell apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902234", "l": "positive regulation of positive thymic T cell selection", "d": ["Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection."], "t": []}], "preferred_name": "positive regulation of positive thymic T cell selection", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0034444", "l": "regulation of plasma lipoprotein oxidation", "d": ["Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma."], "t": []}], "preferred_name": "regulation of plasma lipoprotein oxidation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0072113", "l": "head kidney development", "d": ["The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. 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Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. 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DNA is also damaged because of errors during its replication. 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Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. 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An example of this process is found in Drosophila melanogaster."], "t": []}], "preferred_name": "chitin-based cuticle development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0048145", "l": "regulation of fibroblast proliferation", "d": ["Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells."], "t": []}], "preferred_name": "regulation of fibroblast proliferation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035854", "l": "eosinophil fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. 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The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. 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Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. 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The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain."], "t": []}], "preferred_name": "optic nerve structural organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0007277", "l": "pole cell development", "d": ["The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure."], "t": []}], "preferred_name": "pole cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905467", "l": "positive regulation of G-quadruplex DNA unwinding", "d": ["Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding."], "t": []}], "preferred_name": "positive regulation of G-quadruplex DNA unwinding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0009686", "l": "gibberellin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gibberellin. 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Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control."], "t": []}], "preferred_name": "voluntary skeletal muscle contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:1903564", "l": "regulation of protein localization to cilium", "d": ["Any process that modulates the frequency, rate or extent of protein localization to cilium."], "t": []}], "preferred_name": "regulation of protein localization to cilium", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0002002", "l": "regulation of angiotensin levels in blood", "d": ["The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation."], "t": []}], "preferred_name": "regulation of angiotensin levels in blood", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035984", "l": "cellular response to trichostatin A", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus."], "t": []}], "preferred_name": "cellular response to trichostatin A", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903774", "l": "positive regulation of viral budding via host ESCRT complex", "d": ["Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex."], "t": []}], "preferred_name": "positive regulation of viral budding via host ESCRT complex", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905391", "l": "regulation of protein localization to cell division site involved in cell separation after cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis."], "t": []}], "preferred_name": "regulation of protein localization to cell division site involved in cell separation after cytokinesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0042620", "l": "poly(3-hydroxyalkanoate) metabolic process", "d": ["The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."], "t": []}], "preferred_name": "poly(3-hydroxyalkanoate) metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042702", "l": "uterine wall growth", "d": ["The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels."], "t": []}], "preferred_name": "uterine wall growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045960", "l": "positive regulation of complement activation, classical pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway."], "t": []}], "preferred_name": "positive regulation of complement activation, classical pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001034", "l": "positive regulation of double-strand break repair via nonhomologous end joining", "d": ["Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining."], "t": []}], "preferred_name": "positive regulation of double-strand break repair via nonhomologous end joining", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060062", "l": "Spemann organizer formation at the dorsal lip of the blastopore", "d": ["Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan."], "t": []}], "preferred_name": "Spemann organizer formation at the dorsal lip of the blastopore", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0032802", "l": "low-density lipoprotein particle receptor catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."], "t": []}], "preferred_name": "low-density lipoprotein particle receptor catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903868", "l": "regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "d": ["Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity."], "t": []}], "preferred_name": "regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072005", "l": "maintenance of kidney identity", "d": ["The process in which the identity of a kidney is maintained. 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This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. 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Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol."], "t": []}], "preferred_name": "calcitriol biosynthetic process from calciol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0034616", "l": "response to laminar fluid shear stress", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. 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The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation."], "t": []}], "preferred_name": "prepupal development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0021560", "l": "abducens nerve development", "d": ["The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. 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This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. 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In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. 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Glutathione is used in the first step of the pathway and then regenerated in the second step."], "t": []}], "preferred_name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035309", "l": "wing and notum subfield formation", "d": ["The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures."], "t": []}], "preferred_name": "wing and notum subfield formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:2000571", "l": "regulation of interleukin-4-dependent isotype switching to IgE isotypes", "d": ["Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes."], "t": []}], "preferred_name": "regulation of interleukin-4-dependent isotype switching to IgE isotypes", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000005", "l": "negative regulation of metanephric S-shaped body morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis."], "t": []}], "preferred_name": "negative regulation of metanephric S-shaped body morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.328619724587128", "identifiers": [{"i": "GO:0009806", "l": "lignan metabolic process", "d": ["The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. 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Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded."], "t": []}], "preferred_name": "regulation of low-density lipoprotein particle clearance", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003346", "l": "epicardium-derived cell migration to the myocardium", "d": ["The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium."], "t": []}], "preferred_name": "epicardium-derived cell migration to the myocardium", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035582", "l": "sequestering of BMP in extracellular matrix", "d": ["Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. 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"identifiers": [{"i": "GO:0090517", "l": "L-lysine transmembrane import into vacuole", "d": ["The directed movement of L-lysine into the vacuole across the vacuolar membrane."], "t": []}], "preferred_name": "L-lysine transmembrane import into vacuole", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021849", "l": "neuroblast division in subventricular zone", "d": ["The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially."], "t": []}], "preferred_name": "neuroblast division in subventricular zone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031655", "l": "negative regulation of heat dissipation", "d": ["Any process that stops, prevents, or reduces the rate or extent of heat dissipation."], "t": []}], "preferred_name": "negative regulation of heat dissipation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0072595", "l": "maintenance of protein localization in organelle", "d": ["Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle."], "t": []}], "preferred_name": "maintenance of protein localization in organelle", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903699", "l": "tarsal gland development", "d": ["The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure."], "t": []}], "preferred_name": "tarsal gland development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0015920", "l": "lipopolysaccharide transport", "d": ["The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."], "t": []}], "preferred_name": "lipopolysaccharide transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0034372", "l": "very-low-density lipoprotein particle remodeling", "d": ["The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid."], "t": []}], "preferred_name": "very-low-density lipoprotein particle remodeling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0098756", "l": "response to interleukin-21", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus."], "t": []}], "preferred_name": "response to interleukin-21", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0097282", "l": "immunoglobulin-mediated neutralization", "d": ["The inhibition of an antigen's biological effects by antibody binding to it. 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A major component of the cell wall outer membrane of Gram-negative bacteria."], "t": []}], "preferred_name": "enterobacterial common antigen metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061881", "l": "positive regulation of anterograde axonal transport of mitochondrion", "d": ["Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse."], "t": []}], "preferred_name": "positive regulation of anterograde axonal transport of mitochondrion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:2001058", "l": "D-tagatose 6-phosphate metabolic process", "d": ["The chemical reactions and pathways involving a D-tagatose 6-phosphate."], "t": []}], "preferred_name": "D-tagatose 6-phosphate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075196", "l": "adhesion of symbiont haustorium mother cell to host", "d": ["The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. 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The forelimbs are the front limbs of an animal, e.g. the arms of a human."], "t": []}], "preferred_name": "embryonic forelimb morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0002781", "l": "antifungal peptide production", "d": ["The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels."], "t": []}], "preferred_name": "antifungal peptide production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0006794", "l": "phosphorus utilization", "d": ["A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. 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The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1."], "t": []}], "preferred_name": "epigenetic programing of female pronucleus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0043652", "l": "engulfment of apoptotic cell", "d": ["The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte."], "t": []}], "preferred_name": "engulfment of apoptotic cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903700", "l": "caecum development", "d": ["The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure."], "t": []}], "preferred_name": "caecum development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0043308", "l": "eosinophil degranulation", "d": ["The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil."], "t": []}], "preferred_name": "eosinophil degranulation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.779580099463558", "identifiers": [{"i": "GO:0061061", "l": "muscle structure development", "d": ["The progression of a muscle structure over time, from its formation to its mature state. 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"taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0098515", "l": "detection of low humidity stimulus involved in sensory perception", "d": ["The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity."], "t": []}], "preferred_name": "detection of low humidity stimulus involved in sensory perception", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:2000380", "l": "regulation of mesoderm development", "d": ["Any process that modulates the frequency, rate or extent of mesoderm development."], "t": []}], "preferred_name": "regulation of mesoderm development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.374298741800288", "identifiers": [{"i": "GO:0140353", "l": "lipid export from cell", "d": ["The directed movement of a lipid from a cell, into the extracellular region."], 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In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase."], "t": []}], "preferred_name": "regulation of DNA-templated DNA replication initiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080142", "l": "regulation of salicylic acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid."], "t": []}], "preferred_name": "regulation of salicylic acid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021632", "l": "optic nerve maturation", "d": ["A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. 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TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits."], "t": []}], "preferred_name": "symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900616", "l": "emericellamide A catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of emericellamide A."], "t": []}], "preferred_name": "emericellamide A catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018020", "l": "peptidyl-glutamic acid methylation", "d": ["The addition of a methyl group to a glutamic acid residue in a protein."], "t": []}], "preferred_name": "peptidyl-glutamic acid methylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021750", "l": "vestibular nucleus development", "d": ["The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure."], "t": []}], "preferred_name": "vestibular nucleus development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061033", "l": "secretion by lung epithelial cell involved in lung growth", "d": ["The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development."], "t": []}], "preferred_name": "secretion by lung epithelial cell involved in lung growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905127", "l": "negative regulation of axo-dendritic protein transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport."], "t": []}], "preferred_name": "negative regulation of axo-dendritic protein transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903272", "l": "positive regulation of cytoplasmic translational elongation through polyproline stretches", "d": ["Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches."], "t": []}], "preferred_name": "positive regulation of cytoplasmic translational elongation through polyproline stretches", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000953", "l": "branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway", "d": ["The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. 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Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."], "t": []}], "preferred_name": "cellular response to gonadotropin-releasing hormone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0001912", "l": "positive regulation of leukocyte mediated cytotoxicity", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity."], "t": []}], "preferred_name": "positive regulation of leukocyte mediated cytotoxicity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140725", "l": "detoxification of free heme", "d": ["Any process that reduces or removes the toxicity of free heme. 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It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states."], "t": []}], "preferred_name": "detection of chemical stimulus involved in magnetoreception", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071399", "l": "cellular response to linoleic acid", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus."], "t": []}], "preferred_name": "cellular response to linoleic acid", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1904842", "l": "response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."], "t": []}], "preferred_name": "response to nitroglycerin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901006", "l": "ubiquinone-6 biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone-6."], "t": []}], "preferred_name": "ubiquinone-6 biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0070786", "l": "positive regulation of growth of unicellular organism as a thread of attached cells", "d": ["Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium."], "t": []}], "preferred_name": "positive regulation of growth of unicellular organism as a thread of attached cells", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0045652", "l": "regulation of megakaryocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of megakaryocyte differentiation."], "t": []}], "preferred_name": "regulation of megakaryocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033382", "l": "maintenance of granzyme B location in T cell secretory granule", "d": ["A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere."], "t": []}], "preferred_name": "maintenance of granzyme B location in T cell secretory granule", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090262", "l": "regulation of transcription-coupled nucleotide-excision repair", "d": ["Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "symbiont-mediated suppression of host apoptosis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060488", "l": "orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis", "d": ["The process in which a lung bud bifurcates perpendicular to the plane of the previous bud."], "t": []}], "preferred_name": "orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0035399", "l": "helper T cell enhancement of B cell mediated immune response", "d": ["Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell."], "t": []}], "preferred_name": "helper T cell enhancement of B cell mediated immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0014848", "l": "urinary tract smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. 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These include the kidneys, ureters, bladder, and urethra."], "t": []}], "preferred_name": "urinary tract smooth muscle contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0033388", "l": "putrescine biosynthetic process from arginine", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine."], "t": []}], "preferred_name": "putrescine biosynthetic process from arginine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000512", "l": "negative regulation of granzyme A production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production."], "t": []}], "preferred_name": "negative regulation of granzyme A production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:2000282", "l": "regulation of cellular amino acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process."], "t": []}], "preferred_name": "regulation of cellular amino acid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0097039", "l": "protein linear polyubiquitination", "d": ["A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein."], "t": []}], "preferred_name": "protein linear polyubiquitination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.198594790224185", "identifiers": [{"i": "GO:0040007", "l": "growth", "d": ["The increase in size or mass of an entire organism, a part of an organism or a cell."], "t": []}], "preferred_name": "growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061044", "l": "negative regulation of vascular wound healing", "d": ["Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature."], "t": []}], "preferred_name": "negative regulation of vascular wound healing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.180104376590947", "identifiers": [{"i": "GO:0042181", "l": "ketone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. 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Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter."], "t": []}], "preferred_name": "cellular response to histamine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0042276", "l": "error-prone translesion synthesis", "d": ["The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. 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The zygote overcomes the silencing that has been established. 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Includes processes that both stabilize and destabilize mRNAs."], "t": []}], "preferred_name": "regulation of mRNA stability", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019315", "l": "D-allose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose."], "t": []}], "preferred_name": "D-allose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0002693", "l": "positive regulation of cellular extravasation", "d": ["Any process that activates or increases the frequency, rate, or extent of cellular extravasation."], "t": []}], "preferred_name": "positive regulation of cellular extravasation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0050858", "l": "negative regulation of antigen receptor-mediated signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell."], "t": []}], "preferred_name": "negative regulation of antigen receptor-mediated signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.62457968515541", "identifiers": [{"i": "GO:0046530", "l": "photoreceptor cell differentiation", "d": ["The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster."], "t": []}], "preferred_name": "photoreceptor cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0007008", "l": "outer mitochondrial membrane organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane."], "t": []}], "preferred_name": "outer mitochondrial membrane organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0090598", "l": "male anatomical structure morphogenesis", "d": ["The processes by which anatomical structures that are only present in the male organism are generated and organized."], "t": []}], "preferred_name": "male anatomical structure morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0140499", "l": "negative regulation of mitotic spindle assembly checkpoint signaling", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling."], "t": []}], "preferred_name": "negative regulation of mitotic spindle assembly checkpoint signaling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0099050", "l": "vesicle scission", "d": ["The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane."], "t": []}], "preferred_name": "vesicle scission", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1904816", "l": "positive regulation of protein localization to chromosome, telomeric region", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region."], "t": []}], "preferred_name": "positive regulation of protein localization to chromosome, telomeric region", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903983", "l": "positive regulation of microvillus length", "d": ["A process that increases the length of a microvillus."], "t": []}], "preferred_name": "positive regulation of microvillus length", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000078", "l": "positive regulation of type B pancreatic cell development", "d": ["Any process that activates or increases the frequency, rate or extent of pancreatic B cell development."], "t": []}], "preferred_name": "positive regulation of type B pancreatic cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0044574", "l": "starch utilization system complex assembly", "d": ["The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan."], "t": []}], "preferred_name": "starch utilization system complex assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.721147647610692", "identifiers": [{"i": "GO:0009107", "l": "lipoate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid."], "t": []}], "preferred_name": "lipoate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0039664", "l": "lysis of host organelle involved in viral entry into host cell", "d": ["The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm."], "t": []}], "preferred_name": "lysis of host organelle involved in viral entry into host cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.764380851599824", "identifiers": [{"i": "GO:0043085", "l": "positive regulation of catalytic activity", "d": ["Any process that activates or increases the activity of an enzyme."], "t": []}], "preferred_name": "positive regulation of catalytic activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0035846", "l": "oviduct epithelium development", "d": ["The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct."], "t": []}], "preferred_name": "oviduct epithelium development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:0002360", "l": "T cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell."], "t": []}], "preferred_name": "T cell lineage commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0048619", "l": "embryonic hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase."], "t": []}], "preferred_name": "embryonic hindgut morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0030716", "l": "oocyte fate determination", "d": ["The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed."], "t": []}], "preferred_name": "oocyte fate determination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.897420099510626", "identifiers": [{"i": "GO:0010453", "l": "regulation of cell fate commitment", "d": ["Any process that modulates the frequency, rate or extent of cell fate commitment. 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Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms."], "t": []}], "preferred_name": "response to ziprasidone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018270", "l": "GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine", "d": ["The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein."], "t": []}], "preferred_name": "GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903974", "l": "positive regulation of cellular response to macrophage colony-stimulating factor stimulus", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus."], "t": []}], "preferred_name": "positive regulation of cellular response to macrophage colony-stimulating factor stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "58.305383423946438", "identifiers": [{"i": "GO:0048871", "l": "multicellular organismal-level homeostasis", "d": ["Any process involved in the maintenance of an internal steady state at the level of the multicellular organism."], "t": []}], "preferred_name": "multicellular organismal-level homeostasis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0006142", "l": "regulation of pyrimidine nucleobase metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases."], "t": []}], "preferred_name": "regulation of pyrimidine nucleobase metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1900060", "l": "negative regulation of ceramide biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process."], "t": []}], "preferred_name": "negative regulation of ceramide biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0019988", "l": "charged-tRNA amino acid modification", "d": ["The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine."], "t": []}], "preferred_name": "charged-tRNA amino acid modification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003106", "l": "negative regulation of glomerular filtration by angiotensin", "d": ["The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. 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Cell development does not include the steps involved in committing a cell to a specific fate."], "t": []}], "preferred_name": "posterior lateral line neuromast hair cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1901345", "l": "response to L-thialysine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus."], "t": []}], "preferred_name": "response to L-thialysine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071380", "l": "cellular response to prostaglandin E stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus."], "t": []}], "preferred_name": "cellular response to prostaglandin E stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0035990", "l": "tendon cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance."], "t": []}], "preferred_name": "tendon cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905673", "l": "positive regulation of lysosome organization", "d": ["Any process that activates or increases the frequency, rate or extent of lysosome organization."], "t": []}], "preferred_name": "positive regulation of lysosome organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141111", "l": "positive regulation of cGAS/STING signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of of cGAS/STING signaling pathway."], "t": []}], "preferred_name": "positive regulation of cGAS/STING signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1905582", "l": "response to mannose", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus."], "t": []}], "preferred_name": "response to mannose", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140493", "l": "very long-chain fatty acid beta-oxidation", "d": ["A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. 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The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein."], "t": []}], "preferred_name": "peptide antigen transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.9446391445248", "identifiers": [{"i": "GO:2000108", "l": "positive regulation of leukocyte apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process."], "t": []}], "preferred_name": "positive regulation of leukocyte apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0015808", "l": "L-alanine transport", "d": ["The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "preferred_name": "L-alanine transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0060608", "l": "cell-cell adhesion involved in neural tube closure", "d": ["The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube."], "t": []}], "preferred_name": "cell-cell adhesion involved in neural tube closure", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033499", "l": "galactose catabolic process via UDP-galactose", "d": ["The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose."], "t": []}], "preferred_name": "galactose catabolic process via UDP-galactose", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060989", "l": "lipid tube assembly involved in organelle fusion", "d": ["The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse."], "t": []}], "preferred_name": "lipid tube assembly involved in organelle fusion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1902195", "l": "isovaleryl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving isovaleryl-CoA(4-)."], "t": []}], "preferred_name": "isovaleryl-CoA(4-) metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900702", "l": "negative regulation of orcinol biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process."], "t": []}], "preferred_name": "negative regulation of orcinol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.9446391445248", "identifiers": [{"i": "GO:0018970", "l": "toluene metabolic process", "d": ["The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications."], "t": []}], "preferred_name": "toluene metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.78588058155534", "identifiers": [{"i": "GO:0016032", "l": "viral process", "d": ["A multi-organism process in which a virus is a participant. 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Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion."], "t": []}], "preferred_name": "equilibrioception", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903743", "l": "negative regulation of anterograde synaptic vesicle transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport."], "t": []}], "preferred_name": "negative regulation of anterograde synaptic vesicle transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009099", "l": "valine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid."], "t": []}], "preferred_name": "valine biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003247", "l": "post-embryonic cardiac muscle cell growth involved in heart morphogenesis", "d": ["The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart."], "t": []}], "preferred_name": "post-embryonic cardiac muscle cell growth involved in heart morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000420", "l": "negative regulation of eosinophil extravasation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation."], "t": []}], "preferred_name": "negative regulation of eosinophil extravasation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032194", "l": "ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate."], "t": []}], "preferred_name": "ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072389", "l": "flavin adenine dinucleotide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes."], "t": []}], "preferred_name": "flavin adenine dinucleotide catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903346", "l": "positive regulation of protein polyglycylation", "d": ["Any process that activates or increases the frequency, rate or extent of protein polyglycylation."], "t": []}], "preferred_name": "positive regulation of protein polyglycylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039645", "l": "symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint", "d": ["A process in which a symbiont interferes with the normal execution of the host cell G1/S transition checkpoint. 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A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms."], "t": []}], "preferred_name": "stipule development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0001514", "l": "selenocysteine incorporation", "d": ["The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. 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The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. 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The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros."], "t": []}], "preferred_name": "positive regulation of metanephric glomerulus development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0071026", "l": "cytoplasmic RNA surveillance", "d": ["The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm."], "t": []}], "preferred_name": "cytoplasmic RNA surveillance", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009091", "l": "homoserine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid."], "t": []}], "preferred_name": "homoserine catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0010055", "l": "atrichoblast differentiation", "d": ["The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair."], "t": []}], "preferred_name": "atrichoblast differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "35.188754146646232", "identifiers": [{"i": "GO:0050896", "l": "response to stimulus", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. 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Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA."], "t": []}], "preferred_name": "double stranded viral RNA replication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070157", "l": "mitochondrial prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. 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The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones."], "t": []}], "preferred_name": "ring gland development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0090182", "l": "regulation of secretion of lysosomal enzymes", "d": ["Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell."], "t": []}], "preferred_name": "regulation of secretion of lysosomal enzymes", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0072151", "l": "mesangial cell fate commitment", "d": ["The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell."], "t": []}], "preferred_name": "mesangial cell fate commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.151434559513376", "identifiers": [{"i": "GO:0007160", "l": "cell-matrix adhesion", "d": ["The binding of a cell to the extracellular matrix via adhesion molecules."], "t": []}], "preferred_name": "cell-matrix adhesion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0098719", "l": "sodium ion import across plasma membrane", "d": ["The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "preferred_name": "sodium ion import across plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:2000886", "l": "glucuronoxylan catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan."], "t": []}], "preferred_name": "glucuronoxylan catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.588190044528119", "identifiers": [{"i": "GO:0002921", "l": "negative regulation of humoral immune response", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response."], "t": []}], "preferred_name": "negative regulation of humoral immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.090052188295473", "identifiers": [{"i": "GO:0019062", "l": "virion attachment to host cell", "d": ["The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection."], "t": []}], "preferred_name": "virion attachment to host cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.805212968330153", "identifiers": [{"i": "GO:0120178", "l": "steroid hormone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone."], "t": []}], "preferred_name": "steroid hormone biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "27.799850867468155", "identifiers": [{"i": "GO:0007275", "l": "multicellular organism development", "d": ["The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)."], "t": []}], "preferred_name": "multicellular organism development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0032953", "l": "regulation of (1->3)-beta-D-glucan biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans."], "t": []}], "preferred_name": "regulation of (1->3)-beta-D-glucan biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051391", "l": "tRNA acetylation", "d": ["The modification of tRNA structure by addition of an acetyl group to tRNA. 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Larger structures are transported along microtubules to the cis-Golgi."], "t": []}], "preferred_name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:2001197", "l": "basement membrane assembly involved in embryonic body morphogenesis", "d": ["Any basement membrane assembly that is involved in embryonic body morphogenesis."], "t": []}], "preferred_name": "basement membrane assembly involved in embryonic body morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904205", "l": "negative regulation of skeletal muscle hypertrophy", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy."], "t": []}], "preferred_name": "negative regulation of skeletal muscle hypertrophy", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0062033", "l": "positive regulation of mitotic sister chromatid segregation", "d": ["Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis."], "t": []}], "preferred_name": "positive regulation of mitotic sister chromatid segregation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0051599", "l": "response to hydrostatic pressure", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it."], "t": []}], "preferred_name": "response to hydrostatic pressure", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.788943409855349", "identifiers": [{"i": "GO:0052031", "l": "symbiont-mediated perturbation of host defense response", "d": ["A process in which a symbiont interferes with the ability of the host to mount a defense in response to its presence. 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Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "preferred_name": "endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1900282", "l": "regulation of cellobiose catabolic process", "d": ["Any process that modulates the frequency, rate or extent of cellobiose catabolic process."], "t": []}], "preferred_name": "regulation of cellobiose catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.090052188295473", "identifiers": [{"i": "GO:0032527", "l": "protein exit from endoplasmic reticulum", "d": ["The directed movement of proteins from the endoplasmic reticulum."], "t": []}], "preferred_name": "protein exit from endoplasmic reticulum", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900338", "l": "positive regulation of methane biosynthetic process from carbon monoxide", "d": ["Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide."], "t": []}], "preferred_name": "positive regulation of methane biosynthetic process from carbon monoxide", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0090330", "l": "regulation of platelet aggregation", "d": ["Any process that modulates the rate, frequency or extent of platelet aggregation. 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The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field."], "t": []}], "preferred_name": "camera-type eye development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904611", "l": "cellular response to 3,3',4,4',5-pentachlorobiphenyl", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus."], "t": []}], "preferred_name": "cellular response to 3,3',4,4',5-pentachlorobiphenyl", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000497", "l": "positive regulation of cell proliferation involved in compound eye morphogenesis", "d": ["Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis."], "t": []}], "preferred_name": "positive regulation of cell proliferation involved in compound eye morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0072086", "l": "specification of loop of Henle identity", "d": ["The process in which the loop of Henle of the kidney nephron acquires its identity."], "t": []}], "preferred_name": "specification of loop of Henle identity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060050", "l": "positive regulation of protein glycosylation", "d": ["Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "preferred_name": "cytosolic valyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0019468", "l": "nopaline catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative."], "t": []}], "preferred_name": "nopaline catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0019407", "l": "hexitol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule."], "t": []}], "preferred_name": "hexitol catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0090168", "l": "Golgi reassembly", "d": ["The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance."], "t": []}], "preferred_name": "Golgi reassembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904787", "l": "positive regulation of asymmetric protein localization involved in cell fate determination", "d": ["Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination."], "t": []}], "preferred_name": "positive regulation of asymmetric protein localization involved in cell fate determination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.418420772740944", "identifiers": [{"i": "GO:0048514", "l": "blood vessel morphogenesis", "d": ["The process in which the anatomical structures of blood vessels are generated and organized. 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The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length."], "t": []}], "preferred_name": "long-day photoperiodism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.621676966838109", "identifiers": [{"i": "GO:0010977", "l": "negative regulation of neuron projection development", "d": ["Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)."], "t": []}], "preferred_name": "negative regulation of neuron projection development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903446", "l": "geraniol metabolic process", "d": ["The chemical reactions and pathways involving geraniol."], "t": []}], "preferred_name": "geraniol metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014728", "l": "regulation of the force of skeletal muscle contraction", "d": ["Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. 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The urethra is a renal system organ that carries urine from the bladder to outside the body."], "t": []}], "preferred_name": "urethra development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031283", "l": "negative regulation of guanylate cyclase activity", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity."], "t": []}], "preferred_name": "negative regulation of guanylate cyclase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160020", "l": "positive regulation of ferroptosis", "d": ["Any process that activates or increases the frequency, rate or extent of ferroptosis."], "t": []}], "preferred_name": "positive regulation of ferroptosis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039557", "l": "symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). 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DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication."], "t": []}], "preferred_name": "interstrand cross-link repair", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002486", "l": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "d": ["The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. 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Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase."], "t": []}], "preferred_name": "cellular response to methotrexate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000863", "l": "positive regulation of estrogen secretion", "d": ["Any process that activates or increases the frequency, rate or extent of estrogen secretion."], "t": []}], "preferred_name": "positive regulation of estrogen secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1900826", "l": "negative regulation of membrane depolarization during cardiac muscle cell action potential", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential."], "t": []}], "preferred_name": "negative regulation of membrane depolarization during cardiac muscle cell action potential", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990523", "l": "bone regeneration", "d": ["The regrowth of bone following its loss or destruction."], "t": []}], "preferred_name": "bone regeneration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:2000879", "l": "negative regulation of dipeptide transport", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport."], "t": []}], "preferred_name": "negative regulation of dipeptide transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0032656", "l": "regulation of interleukin-13 production", "d": ["Any process that modulates the frequency, rate, or extent of interleukin-13 production."], "t": []}], "preferred_name": "regulation of interleukin-13 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0060916", "l": "mesenchymal cell proliferation involved in lung development", "d": ["The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. 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Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified."], "t": []}], "preferred_name": "epithelial cell differentiation involved in mammary gland cord morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902951", "l": "negative regulation of dendritic spine maintenance", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance."], "t": []}], "preferred_name": "negative regulation of dendritic spine maintenance", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:1901420", "l": "negative regulation of response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol."], "t": []}], "preferred_name": "negative regulation of response to alcohol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0001814", "l": "negative regulation of antibody-dependent cellular cytotoxicity", "d": ["Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity."], "t": []}], "preferred_name": "negative regulation of antibody-dependent cellular cytotoxicity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090453", "l": "aspartate transmembrane import into vacuole", "d": ["The directed movement of aspartate into the vacuole across the vacuolar membrane."], "t": []}], "preferred_name": "aspartate transmembrane import into vacuole", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0120194", "l": "regulation of anther dehiscence", "d": ["Any process involved in the dehiscence of an anther to release the pollen grains contained within it."], "t": []}], "preferred_name": "regulation of anther dehiscence", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060273", "l": "crying behavior", "d": ["The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli."], "t": []}], "preferred_name": "crying behavior", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900792", "l": "shamixanthone catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of shamixanthone."], "t": []}], "preferred_name": "shamixanthone catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070809", "l": "negative regulation of Hulle cell development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body."], "t": []}], "preferred_name": "negative regulation of Hulle cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904597", "l": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response."], "t": []}], "preferred_name": "negative regulation of connective tissue replacement involved in inflammatory response wound healing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035321", "l": "maintenance of imaginal disc-derived wing hair orientation", "d": ["Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity."], "t": []}], "preferred_name": "maintenance of imaginal disc-derived wing hair orientation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900562", "l": "dehydroaustinol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dehydroaustinol."], "t": []}], "preferred_name": "dehydroaustinol catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "15.159445204362202", "identifiers": [{"i": "GO:0008150", "l": "biological_process", "d": ["A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence."], "t": []}], "preferred_name": "biological_process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048173", "l": "positive regulation of short-term neuronal synaptic plasticity", "d": ["A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. 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This process pertains to the physical shaping of a rudimentary structure."], "t": []}], "preferred_name": "intermediate mesoderm structural organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072764", "l": "cellular response to reversine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus."], "t": []}], "preferred_name": "cellular response to reversine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0072003", "l": "kidney rudiment formation", "d": ["The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "preferred_name": "kidney rudiment formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901770", "l": "daunorubicin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of daunorubicin."], "t": []}], "preferred_name": "daunorubicin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904312", "l": "cellular response to gold(3+)", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus."], "t": []}], "preferred_name": "cellular response to gold(3+)", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.978582888531797", "identifiers": [{"i": "GO:0030036", "l": "actin cytoskeleton organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins."], "t": []}], "preferred_name": "actin cytoskeleton organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1905958", "l": "negative regulation of cellular response to alcohol", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol."], "t": []}], "preferred_name": "negative regulation of cellular response to alcohol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000103", "l": "positive regulation of mammary stem cell proliferation", "d": ["Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation."], "t": []}], "preferred_name": "positive regulation of mammary stem cell proliferation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140879", "l": "conidiogenone biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation."], "t": []}], "preferred_name": "conidiogenone biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0051593", "l": "response to folic acid", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus."], "t": []}], "preferred_name": "response to folic acid", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0140735", "l": "lovastatin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR)."], "t": []}], "preferred_name": "lovastatin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1902192", "l": "2-methylbut-2-enoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-)."], "t": []}], "preferred_name": "2-methylbut-2-enoyl-CoA(4-) metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035203", "l": "regulation of lamellocyte differentiation", "d": ["Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes."], "t": []}], "preferred_name": "regulation of lamellocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0019499", "l": "cyanide metabolic process", "d": ["The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain."], "t": []}], "preferred_name": "cyanide metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1904758", "l": "protein localization to new growing cell tip", "d": ["A process in which a protein is transported to, or maintained in, a location within a new growing cell tip."], "t": []}], "preferred_name": "protein localization to new growing cell tip", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009708", "l": "benzyl isoquinoline alkaloid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings."], "t": []}], "preferred_name": "benzyl isoquinoline alkaloid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061367", "l": "behavioral response to acetic acid induced pain", "d": ["Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus."], "t": []}], "preferred_name": "behavioral response to acetic acid induced pain", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098747", "l": "slow, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release."], "t": []}], "preferred_name": "slow, calcium ion-dependent exocytosis of neurotransmitter", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0060290", "l": "transdifferentiation", "d": ["The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate."], "t": []}], "preferred_name": "transdifferentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0090235", "l": "regulation of metaphase plate congression", "d": ["Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle."], "t": []}], "preferred_name": "regulation of metaphase plate congression", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010849", "l": "regulation of proton-transporting ATPase activity, rotational mechanism", "d": ["Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."], "t": []}], "preferred_name": "regulation of proton-transporting ATPase activity, rotational mechanism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0070243", "l": "regulation of thymocyte apoptotic process", "d": ["Any process that modulates the occurrence or rate of thymocyte death by apoptotic process."], "t": []}], "preferred_name": "regulation of thymocyte apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902870", "l": "negative regulation of amacrine cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation."], "t": []}], "preferred_name": "negative regulation of amacrine cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904753", "l": "negative regulation of vascular associated smooth muscle cell migration", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration."], "t": []}], "preferred_name": "negative regulation of vascular associated smooth muscle cell migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0072064", "l": "long descending thin limb development", "d": ["The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla."], "t": []}], "preferred_name": "long descending thin limb development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.721147647610692", "identifiers": [{"i": "GO:0002313", "l": "mature B cell differentiation involved in immune response", "d": ["The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response."], "t": []}], "preferred_name": "mature B cell differentiation involved in immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043377", "l": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation."], "t": []}], "preferred_name": "negative regulation of CD8-positive, alpha-beta T cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0006105", "l": "succinate metabolic process", "d": ["The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. 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Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. 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This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse."], "t": []}], "preferred_name": "myotube cell development involved in skeletal muscle regeneration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0071451", "l": "cellular response to superoxide", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "regulation of formation by symbiont of haustorium for nutrient acquisition from host", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0055118", "l": "negative regulation of cardiac muscle contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction."], "t": []}], "preferred_name": "negative regulation of cardiac muscle contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140146", "l": "calcium ion import into vacuole", "d": ["The directed movement of calcium cations into the vacuole across the vacuolar membrane."], "t": []}], "preferred_name": "calcium ion import into vacuole", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0018912", "l": "1,4-dichlorobenzene metabolic process", "d": ["The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs."], "t": []}], "preferred_name": "1,4-dichlorobenzene metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0006235", "l": "dTTP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate."], "t": []}], "preferred_name": "dTTP biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030211", "l": "heparin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."], "t": []}], "preferred_name": "heparin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0060977", "l": "coronary vasculature morphogenesis", "d": ["The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood."], "t": []}], "preferred_name": "coronary vasculature morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0052703", "l": "cellular modified histidine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid."], "t": []}], "preferred_name": "cellular modified histidine biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0071063", "l": "sensory perception of wind", "d": ["The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal."], "t": []}], "preferred_name": "sensory perception of wind", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0007084", "l": "mitotic nuclear membrane reassembly", "d": ["The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. 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Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)."], "t": []}], "preferred_name": "sensory perception of touch", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140734", "l": "ammonium excretion", "d": ["The elimination of ammonium ions from an excretory cell."], "t": []}], "preferred_name": "ammonium excretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009879", "l": "determination of radial symmetry", "d": ["The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis."], "t": []}], "preferred_name": "determination of radial symmetry", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0090371", "l": "regulation of glycerol transport", "d": ["Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "preferred_name": "regulation of glycerol transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.928369586049996", "identifiers": [{"i": "GO:0002644", "l": "negative regulation of tolerance induction", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction."], "t": []}], "preferred_name": "negative regulation of tolerance induction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.479506983467815", "identifiers": [{"i": "GO:0060173", "l": "limb development", "d": ["The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. 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Examples include legs, arms or some types of fin."], "t": []}], "preferred_name": "limb development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0006919", "l": "activation of cysteine-type endopeptidase activity involved in apoptotic process", "d": ["Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process."], "t": []}], "preferred_name": "activation of cysteine-type endopeptidase activity involved in apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904055", "l": "negative regulation of cholangiocyte proliferation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation."], "t": []}], "preferred_name": "negative regulation of cholangiocyte proliferation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0033069", "l": "ansamycin metabolic process", "d": ["The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity."], "t": []}], "preferred_name": "ansamycin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0072118", "l": "pronephros structural organization", "d": ["The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life."], "t": []}], "preferred_name": "pronephros structural organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0036342", "l": "post-anal tail morphogenesis", "d": ["The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. 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The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells."], "t": []}], "preferred_name": "cerebellar molecular layer development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0106135", "l": "negative regulation of cardiac muscle cell contraction", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction."], "t": []}], "preferred_name": "negative regulation of cardiac muscle cell contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "29.501157747698294", "identifiers": [{"i": "GO:0009791", "l": "post-embryonic development", "d": ["The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development."], "t": []}], "preferred_name": "post-embryonic development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0061669", "l": "spontaneous neurotransmitter secretion", "d": ["Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential."], "t": []}], "preferred_name": "spontaneous neurotransmitter secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0002943", "l": "tRNA dihydrouridine synthesis", "d": ["The process whereby a uridine in a transfer RNA is converted to dihydrouridine."], "t": []}], "preferred_name": "tRNA dihydrouridine synthesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0002326", "l": "B cell lineage commitment", "d": ["The process in which a lymphoid progenitor cell becomes committed to become any type of B cell."], "t": []}], "preferred_name": "B cell lineage commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1905092", "l": "response to diosgenin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus."], "t": []}], "preferred_name": "response to diosgenin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071291", "l": "cellular response to selenium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion."], "t": []}], "preferred_name": "cellular response to selenium ion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903031", "l": "regulation of microtubule plus-end binding", "d": ["Any process that modulates the frequency, rate or extent of microtubule plus-end binding."], "t": []}], "preferred_name": "regulation of microtubule plus-end binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1905906", "l": "regulation of amyloid fibril formation", "d": ["Any process that modulates the frequency, rate or extent of amyloid fibril formation."], "t": []}], "preferred_name": "regulation of amyloid fibril formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0015834", "l": "peptidoglycan-associated peptide transport", "d": ["The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. 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The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. 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This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells."], "t": []}], "preferred_name": "cerebellar Purkinje cell layer formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0033590", "l": "response to cobalamin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus."], "t": []}], "preferred_name": "response to cobalamin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.328619724587128", "identifiers": [{"i": "GO:0070943", "l": "neutrophil-mediated killing of symbiont cell", "d": ["The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "neutrophil-mediated killing of symbiont cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070154", "l": "mitochondrial lysyl-tRNA aminoacylation", "d": ["The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. 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Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate."], "t": []}], "preferred_name": "oscillatory cAMP signaling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035231", "l": "cytoneme assembly", "d": ["Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell."], "t": []}], "preferred_name": "cytoneme assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.279712832799405", "identifiers": [{"i": "GO:0072676", "l": "lymphocyte migration", "d": ["The movement of a lymphocyte within or between different tissues and organs of the body."], "t": []}], "preferred_name": "lymphocyte migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002650", "l": "negative regulation of tolerance induction to self antigen", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or 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The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. 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The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. 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Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells."], "t": []}], "preferred_name": "gamma-delta T cell differentiation involved in immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010215", "l": "cellulose microfibril organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall."], "t": []}], "preferred_name": "cellulose microfibril organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0070672", "l": "response to interleukin-15", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus."], "t": []}], "preferred_name": "response to interleukin-15", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0031036", "l": "myosin II filament assembly", "d": ["The formation of a bipolar filament composed of myosin II molecules."], "t": []}], "preferred_name": "myosin II filament assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0000381", "l": "regulation of alternative mRNA splicing, via spliceosome", "d": ["Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs."], "t": []}], "preferred_name": "regulation of alternative mRNA splicing, via spliceosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0007138", "l": "meiotic anaphase II", "d": ["The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II."], "t": []}], "preferred_name": "meiotic anaphase II", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0060974", "l": "cell migration involved in heart formation", "d": ["The orderly movement of a cell from one site to another that contribute to the formation of the heart. 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Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs."], "t": []}], "preferred_name": "response to red or far red light", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1901096", "l": "regulation of autophagosome maturation", "d": ["Any process that modulates the frequency, rate or extent of autophagosome maturation."], "t": []}], "preferred_name": "regulation of autophagosome maturation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010782", "l": "proboscis morphogenesis, labial disc-derived", "d": ["The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized."], "t": []}], "preferred_name": "proboscis morphogenesis, labial disc-derived", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035437", "l": "maintenance of protein localization in endoplasmic reticulum", "d": ["Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum."], "t": []}], "preferred_name": "maintenance of protein localization in endoplasmic reticulum", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0002590", "l": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I."], "t": []}], "preferred_name": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.9446391445248", "identifiers": [{"i": "GO:0018158", "l": "protein oxidation", "d": ["The modification of a protein amino acid by oxidation."], "t": []}], "preferred_name": "protein oxidation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051659", "l": "maintenance of mitochondrion location", "d": ["Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere."], "t": []}], "preferred_name": "maintenance of mitochondrion location", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061198", "l": "fungiform papilla formation", "d": ["The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue."], "t": []}], "preferred_name": "fungiform papilla formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060578", "l": "superior vena cava morphogenesis", "d": ["The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart."], "t": []}], "preferred_name": "superior vena cava morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0170044", "l": "non-proteinogenic amino acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids."], "t": []}], "preferred_name": "non-proteinogenic amino acid catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070148", "l": "mitochondrial glutaminyl-tRNA aminoacylation", "d": ["The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "preferred_name": "mitochondrial glutaminyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.800420664837461", "identifiers": [{"i": "GO:0042335", "l": "cuticle development", "d": ["The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss."], "t": []}], "preferred_name": "cuticle development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0071694", "l": "maintenance of protein location in extracellular region", "d": ["Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere."], "t": []}], "preferred_name": "maintenance of protein location in extracellular region", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0052864", "l": "1-deoxy-D-xylulose 5-phosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis."], "t": []}], "preferred_name": "1-deoxy-D-xylulose 5-phosphate catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.374926056427483", "identifiers": [{"i": "GO:0033157", "l": "regulation of intracellular protein transport", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells."], "t": []}], "preferred_name": "regulation of intracellular protein transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990383", "l": "cellular response to biotin starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin."], "t": []}], "preferred_name": "cellular response to biotin starvation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1903713", "l": "asparagine transmembrane transport", "d": ["The directed movement of asparagine across a membrane."], "t": []}], "preferred_name": "asparagine transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:2000311", "l": "regulation of AMPA receptor activity", "d": ["Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity."], "t": []}], "preferred_name": "regulation of AMPA receptor activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043953", "l": "protein transport by the Tat complex", "d": ["The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex."], "t": []}], "preferred_name": "protein transport by the Tat complex", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0071839", "l": "apoptotic process in bone marrow cell", "d": ["The apoptotic process in cells in the bone marrow."], "t": []}], "preferred_name": "apoptotic process in bone marrow cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071471", "l": "cellular response to non-ionic osmotic stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment."], "t": []}], "preferred_name": "cellular response to non-ionic osmotic stress", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.809139995051851", "identifiers": [{"i": "GO:0061540", "l": "octopamine secretion, neurotransmission", "d": ["The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter."], "t": []}], "preferred_name": "octopamine secretion, neurotransmission", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.345366160839191", "identifiers": [{"i": "GO:0035930", "l": "corticosteroid hormone secretion", "d": ["The regulated release of any corticosteroid hormone into the circulatory system."], "t": []}], "preferred_name": "corticosteroid hormone secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003358", "l": "noradrenergic neuron development", "d": ["The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell."], "t": []}], "preferred_name": "noradrenergic neuron development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002334", "l": "transitional two stage B cell differentiation", "d": ["The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21."], "t": []}], "preferred_name": "transitional two stage B cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0046627", "l": "negative regulation of insulin receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling."], "t": []}], "preferred_name": "negative regulation of insulin receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0050968", "l": "detection of chemical stimulus involved in sensory perception of pain", "d": ["The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal."], "t": []}], "preferred_name": "detection of chemical stimulus involved in sensory perception of pain", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0046533", "l": "negative regulation of photoreceptor cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster."], "t": []}], "preferred_name": "negative regulation of photoreceptor cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141025", "l": "adhesion of symbiont to host cell surface via host glycoprotein", "d": ["The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "adhesion of symbiont to host cell surface via host glycoprotein", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0043634", "l": "polyadenylation-dependent ncRNA catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA."], "t": []}], "preferred_name": "polyadenylation-dependent ncRNA catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.25002861897768", "identifiers": [{"i": "GO:0021879", "l": "forebrain neuron differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain."], "t": []}], "preferred_name": "forebrain neuron differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002881", "l": "negative regulation of chronic inflammatory response to non-antigenic stimulus", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus."], "t": []}], "preferred_name": "negative regulation of chronic inflammatory response to non-antigenic stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060380", "l": "regulation of single-stranded telomeric DNA binding", "d": ["Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA."], "t": []}], "preferred_name": "regulation of single-stranded telomeric DNA binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1901163", "l": "regulation of trophoblast cell migration", "d": ["Any process that modulates the frequency, rate or extent of trophoblast cell migration."], "t": []}], "preferred_name": "regulation of trophoblast cell migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0071560", "l": "cellular response to transforming growth factor beta stimulus", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus."], "t": []}], "preferred_name": "cellular response to transforming growth factor beta stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0018948", "l": "xylene metabolic process", "d": ["The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene."], "t": []}], "preferred_name": "xylene metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1904811", "l": "positive regulation of dense core granule transport", "d": ["Any process that activates or increases the frequency, rate or extent of dense core granule transport."], "t": []}], "preferred_name": "positive regulation of dense core granule transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0090018", "l": "posterior neural plate formation", "d": ["The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate."], "t": []}], "preferred_name": "posterior neural plate formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990864", "l": "response to growth hormone-releasing hormone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins."], "t": []}], "preferred_name": "response to growth hormone-releasing hormone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.012008383318729", "identifiers": [{"i": "GO:0006997", "l": "nucleus organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus."], "t": []}], "preferred_name": "nucleus organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032705", "l": "negative regulation of interleukin-21 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production."], "t": []}], "preferred_name": "negative regulation of interleukin-21 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0043313", "l": "regulation of neutrophil degranulation", "d": ["Any process that modulates the frequency, rate, or extent of neutrophil degranulation."], "t": []}], "preferred_name": "regulation of neutrophil degranulation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002297", "l": "T-helper 2 cell lineage commitment", "d": ["The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy."], "t": []}], "preferred_name": "T-helper 2 cell lineage commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061040", "l": "female gonad morphogenesis", "d": ["The process in which a female gonad is generated and organized."], "t": []}], "preferred_name": "female gonad morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0019244", "l": "lactate biosynthetic process from pyruvate", "d": ["The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate."], "t": []}], "preferred_name": "lactate biosynthetic process from pyruvate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0036017", "l": "response to erythropoietin", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis."], "t": []}], "preferred_name": "response to erythropoietin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0046092", "l": "deoxycytidine metabolic process", "d": ["The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA."], "t": []}], "preferred_name": "deoxycytidine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010060", "l": "negative regulation of atrichoblast fate specification", "d": ["Any process that suppresses atrichoblast fate specification."], "t": []}], "preferred_name": "negative regulation of atrichoblast fate specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009942", "l": "longitudinal axis specification", "d": ["The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root."], "t": []}], "preferred_name": "longitudinal axis specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002156", "l": "negative regulation of thyroid hormone receptor signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway."], "t": []}], "preferred_name": "negative regulation of thyroid hormone receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1905027", "l": "regulation of membrane depolarization during AV node cell action potential", "d": ["Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential."], "t": []}], "preferred_name": "regulation of membrane depolarization during AV node cell action potential", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039505", "l": "symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II", "d": ["A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class II protein complex."], "t": []}], "preferred_name": "symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1900578", "l": "gerfelin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of gerfelin."], "t": []}], "preferred_name": "gerfelin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0009252", "l": "peptidoglycan biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls."], "t": []}], "preferred_name": "peptidoglycan biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:2000856", "l": "negative regulation of mineralocorticoid secretion", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion."], "t": []}], "preferred_name": "negative regulation of mineralocorticoid secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160048", "l": "craniofacial suture closure", "d": ["The process of fusing together the edges of a craniofacial suture."], "t": []}], "preferred_name": "craniofacial suture closure", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0061218", "l": "negative regulation of mesonephros development", "d": ["Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "preferred_name": "negative regulation of mesonephros development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099561", "l": "synaptic membrane adhesion to extracellular matrix", "d": ["The binding of a synaptic membrane to the extracellular matrix via adhesion molecules."], "t": []}], "preferred_name": "synaptic membrane adhesion to extracellular matrix", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097316", "l": "cellular response to N-acetyl-D-glucosamine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus."], "t": []}], "preferred_name": "cellular response to N-acetyl-D-glucosamine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071995", "l": "phytochelatin import into vacuole", "d": ["The directed movement of phytochelatins into the vacuole. 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It is a cerebral stimulant and narcotic."], "t": []}], "preferred_name": "cocaine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.118009064726436", "identifiers": [{"i": "GO:1903039", "l": "positive regulation of leukocyte cell-cell adhesion", "d": ["Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion."], "t": []}], "preferred_name": "positive regulation of leukocyte cell-cell adhesion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0051935", "l": "glutamate reuptake", "d": ["The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters."], "t": []}], "preferred_name": "glutamate reuptake", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001042", "l": "negative regulation of septum digestion after cytokinesis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis."], "t": []}], "preferred_name": "negative regulation of septum digestion after cytokinesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.560648264911265", "identifiers": [{"i": "GO:0071827", "l": "plasma lipoprotein particle organization", "d": ["A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. 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Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor."], "t": []}], "preferred_name": "cellular response to fluoxetine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048380", "l": "negative regulation of lateral mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification."], "t": []}], "preferred_name": "negative regulation of lateral mesodermal cell fate specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0100011", "l": "positive regulation of fever generation by prostaglandin secretion", "d": ["Any prostaglandin secretion process that positively_regulates fever generation."], "t": []}], "preferred_name": "positive regulation of fever generation by prostaglandin secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0043054", "l": "dauer exit", "d": ["Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development."], "t": []}], "preferred_name": "dauer exit", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1901107", "l": "granaticin metabolic process", "d": ["The chemical reactions and pathways involving granaticin."], "t": []}], "preferred_name": "granaticin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905259", "l": "negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress."], "t": []}], "preferred_name": "negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900349", "l": "negative regulation of methane biosynthetic process from methylamine", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine."], "t": []}], "preferred_name": "negative regulation of methane biosynthetic process from methylamine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006640", "l": "monoacylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified."], "t": []}], "preferred_name": "monoacylglycerol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0001878", "l": "response to yeast", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species."], "t": []}], "preferred_name": "response to yeast", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905701", "l": "positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane", "d": ["Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. 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the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins."], "t": []}], "preferred_name": "mannosamine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010186", "l": "positive regulation of cellular defense response", "d": ["Any process that activates or increases the frequency, rate or extent of cellular defense response."], "t": []}], "preferred_name": "positive regulation of cellular defense response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "64.779580099463558", "identifiers": [{"i": "GO:0033044", "l": "regulation of chromosome organization", "d": ["Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome."], "t": []}], "preferred_name": "regulation of chromosome organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0043452", "l": "cellular alkyne metabolic process", "d": ["The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells."], "t": []}], "preferred_name": "cellular alkyne metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048351", "l": "negative regulation of paraxial mesodermal cell fate specification", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification."], "t": []}], "preferred_name": "negative regulation of paraxial mesodermal cell fate specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141115", "l": "symbiont-mediated suppression of host complement activation by inactivation of complement proteins", "d": ["A process by which a symbiont disrupts or prematurely activates host complement so that its microbial-destroying activities fail."], "t": []}], "preferred_name": "symbiont-mediated suppression of host complement activation by inactivation of complement proteins", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0036048", "l": "protein desuccinylation", "d": ["The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein."], "t": []}], "preferred_name": "protein desuccinylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0031394", "l": "positive regulation of prostaglandin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin."], "t": []}], "preferred_name": "positive regulation of prostaglandin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010342", "l": "endosperm cellularization", "d": ["The separation of the multi-nucleate endosperm into individual cells. 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This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization."], "t": []}], "preferred_name": "endosperm cellularization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046754", "l": "viral exocytosis", "d": ["The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle."], "t": []}], "preferred_name": "viral exocytosis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140544", "l": "septin collar organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar."], "t": []}], "preferred_name": "septin collar organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071286", "l": "cellular response to magnesium ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus."], "t": []}], "preferred_name": "cellular response to magnesium ion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007639", "l": "homeostasis of number of meristem cells", "d": ["Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem."], "t": []}], "preferred_name": "homeostasis of number of meristem cells", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0046755", "l": "viral budding", "d": ["A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space."], "t": []}], "preferred_name": "viral budding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0039014", "l": "cell differentiation involved in pronephros development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state."], "t": []}], "preferred_name": "cell differentiation involved in pronephros development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0061502", "l": "early endosome to recycling endosome transport", "d": ["The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes."], "t": []}], "preferred_name": "early endosome to recycling endosome transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.680315530880364", "identifiers": [{"i": "GO:0006998", "l": "nuclear envelope organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope."], "t": []}], "preferred_name": "nuclear envelope organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0019567", "l": "arabinose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose."], "t": []}], "preferred_name": "arabinose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060318", "l": "definitive erythrocyte differentiation", "d": ["Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis."], "t": []}], "preferred_name": "definitive erythrocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0031952", "l": "regulation of protein autophosphorylation", "d": ["Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues."], "t": []}], "preferred_name": "regulation of protein autophosphorylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021755", "l": "eurydendroid cell differentiation", "d": ["The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. 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The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds."], "t": []}], "preferred_name": "regulation of neural crest formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003111", "l": "positive regulation of heart rate by circulating epinephrine", "d": ["The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction."], "t": []}], "preferred_name": "positive regulation of heart rate by circulating epinephrine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1900579", "l": "(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process", "d": ["The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol."], "t": []}], "preferred_name": "(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0075214", "l": "spore encystment", "d": ["The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. 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When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids."], "t": []}], "preferred_name": "aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0048821", "l": "erythrocyte development", "d": ["The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure."], "t": []}], "preferred_name": "erythrocyte development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0018925", "l": "m-cresol metabolic process", "d": ["The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes."], "t": []}], "preferred_name": "m-cresol metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900459", "l": "positive regulation of brassinosteroid mediated signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway."], "t": []}], "preferred_name": "positive regulation of brassinosteroid mediated signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0120060", "l": "regulation of gastric emptying", "d": ["Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum."], "t": []}], "preferred_name": "regulation of gastric emptying", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0072186", "l": "metanephric cap morphogenesis", "d": ["The process in which the anatomical structures of the metanephric cap are generated and organized. 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The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands."], "t": []}], "preferred_name": "Mo-molybdopterin cofactor catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.778909590344668", "identifiers": [{"i": "GO:0051283", "l": "negative regulation of sequestering of calcium ion", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system."], "t": []}], "preferred_name": "negative regulation of sequestering of calcium ion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902436", "l": "negative regulation of male mating behavior", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior."], "t": []}], "preferred_name": "negative regulation of male mating behavior", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0031443", "l": "fast-twitch skeletal muscle fiber contraction", "d": ["A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability."], "t": []}], "preferred_name": "fast-twitch skeletal muscle fiber contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1900846", "l": "regulation of naphtho-gamma-pyrone biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process."], "t": []}], "preferred_name": "regulation of naphtho-gamma-pyrone biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1902189", "l": "2-methylbutanoyl-CoA(4-) metabolic process", "d": ["The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-)."], "t": []}], "preferred_name": "2-methylbutanoyl-CoA(4-) metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.116992374598524", "identifiers": [{"i": "GO:0030217", "l": "T cell differentiation", "d": ["The process in which a precursor cell type acquires characteristics of a more mature T-cell. 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Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families."], "t": []}], "preferred_name": "response to type I interferon", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901901", "l": "regulation of protein localization to cell division site involved in cytokinesis", "d": ["Any regulation of protein localization to cell division site that is involved in cytokinesis."], "t": []}], "preferred_name": "regulation of protein localization to cell division site involved in cytokinesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.432439127773328", "identifiers": [{"i": "GO:0032101", "l": "regulation of response to external stimulus", "d": ["Any process that modulates the frequency, rate or extent of a response to an external stimulus."], "t": []}], "preferred_name": "regulation of response to external stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060141", "l": "positive regulation of syncytium formation by virus", "d": ["The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells."], "t": []}], "preferred_name": "positive regulation of syncytium formation by virus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032727", "l": "positive regulation of interferon-alpha production", "d": ["Any process that activates or increases the frequency, rate, or extent of interferon-alpha production."], "t": []}], "preferred_name": "positive regulation of interferon-alpha production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019044", "l": "maintenance of viral latency", "d": ["The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms."], "t": []}], "preferred_name": "maintenance of viral latency", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902955", "l": "positive regulation of early endosome to recycling endosome transport", "d": ["Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport."], "t": []}], "preferred_name": "positive regulation of early endosome to recycling endosome transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900624", "l": "negative regulation of monocyte aggregation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation."], "t": []}], "preferred_name": "negative regulation of monocyte aggregation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021902", "l": "commitment of neuronal cell to specific neuron type in forebrain", "d": ["The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain."], "t": []}], "preferred_name": "commitment of neuronal cell to specific neuron type in forebrain", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0002760", "l": "positive regulation of antimicrobial humoral response", "d": ["Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response."], "t": []}], "preferred_name": "positive regulation of antimicrobial humoral response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018284", "l": "iron incorporation into protein via tetrakis-L-cysteinyl iron", "d": ["The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein)."], "t": []}], "preferred_name": "iron incorporation into protein via tetrakis-L-cysteinyl iron", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.621676966838109", "identifiers": [{"i": "GO:0050960", "l": "detection of temperature stimulus involved in thermoception", "d": ["The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception."], "t": []}], "preferred_name": "detection of temperature stimulus involved in thermoception", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0099627", "l": "neurotransmitter receptor cycle", "d": ["The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. 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"preferred_name": "protein C-linked glycosylation via tryptophan", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0044739", "l": "positive regulation of acid-sensing ion channel in another organism", "d": ["Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism."], "t": []}], "preferred_name": "positive regulation of acid-sensing ion channel in another organism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905751", "l": "positive regulation of endosome to plasma membrane protein transport", "d": ["Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport."], "t": []}], "preferred_name": "positive regulation of endosome to plasma membrane protein transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0060896", "l": "neural plate pattern specification", "d": ["The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate."], "t": []}], "preferred_name": "neural plate pattern specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903003", "l": "positive regulation of protein deubiquitination", "d": ["Any process that activates or increases the frequency, rate or extent of protein deubiquitination."], "t": []}], "preferred_name": "positive regulation of protein deubiquitination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "65.691532569937081", "identifiers": [{"i": "GO:0072657", "l": "protein localization to membrane", "d": ["A process in which a protein is transported to, or maintained in, a specific location in a membrane."], "t": []}], "preferred_name": "protein localization to membrane", 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A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation."], "t": []}], "preferred_name": "cellular response to bacteriocin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070152", "l": "mitochondrial isoleucyl-tRNA aminoacylation", "d": ["The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. 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The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism."], "t": []}], "preferred_name": "sulfur utilization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.948566171246497", "identifiers": [{"i": "GO:0097006", "l": "regulation of plasma lipoprotein particle levels", "d": ["Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism."], "t": []}], "preferred_name": "regulation of plasma lipoprotein particle levels", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905448", "l": "positive regulation of mitochondrial ATP synthesis coupled electron transport", "d": ["Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport."], "t": []}], "preferred_name": "positive regulation of mitochondrial ATP synthesis coupled electron transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0014846", "l": "esophagus smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. 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The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract."], "t": []}], "preferred_name": "esophagus smooth muscle contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905678", "l": "negative regulation of adaptive immune effector response", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response."], "t": []}], "preferred_name": "negative regulation of adaptive immune effector response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0000463", "l": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "d": ["Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA 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[{"i": "GO:0032525", "l": "somite rostral/caudal axis specification", "d": ["The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary."], "t": []}], "preferred_name": "somite rostral/caudal axis specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903408", "l": "positive regulation of P-type sodium:potassium-exchanging transporter activity", "d": ["Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity."], "t": []}], "preferred_name": "positive regulation of P-type sodium:potassium-exchanging transporter activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0090296", "l": "regulation of mitochondrial DNA replication", "d": ["Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are 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"epithelial cell morphogenesis involved in gastrulation", "d": ["The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation."], "t": []}], "preferred_name": "epithelial cell morphogenesis involved in gastrulation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903866", "l": "palisade mesophyll development", "d": ["The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure."], "t": []}], "preferred_name": "palisade mesophyll development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0030974", "l": "thiamine pyrophosphate transmembrane transport", "d": ["The process in which thiamine pyrophosphate is transported across a membrane."], "t": []}], "preferred_name": "thiamine pyrophosphate transmembrane transport", "taxa": 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"biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0045346", "l": "regulation of MHC class II biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II."], "t": []}], "preferred_name": "regulation of MHC class II biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902362", "l": "melanocyte apoptotic process", "d": ["Any apoptotic process in a melanocyte, the main structural component of the epidermis."], "t": []}], "preferred_name": "melanocyte apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042459", "l": "octopine catabolic process to proline", "d": ["The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline."], "t": []}], "preferred_name": "octopine catabolic process 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Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript."], "t": []}], "preferred_name": "endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0000909", "l": "sporocarp development involved in sexual reproduction", "d": ["The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi."], "t": []}], "preferred_name": "sporocarp development involved in sexual reproduction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "28.657091916083949", "identifiers": [{"i": "GO:0009790", "l": "embryo development", "d": ["The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant."], "t": []}], "preferred_name": "embryo development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902786", "l": "response to dodecane", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus."], "t": []}], "preferred_name": "response to dodecane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098004", "l": "virus tail fiber assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber."], "t": []}], "preferred_name": "virus tail fiber assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051683", "l": "establishment of Golgi localization", "d": ["The directed movement of the Golgi to a specific location."], "t": []}], "preferred_name": "establishment of Golgi localization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1905242", "l": "response to 3,3',5-triiodo-L-thyronine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus."], "t": []}], "preferred_name": "response to 3,3',5-triiodo-L-thyronine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902602", "l": "aluminum ion transmembrane transport", "d": ["The directed movement of aluminium ions across a membrane."], "t": []}], "preferred_name": "aluminum ion transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900093", "l": "positive regulation of raffinose biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process."], "t": []}], "preferred_name": "positive regulation of raffinose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "52.519908933309509", "identifiers": [{"i": "GO:0002682", "l": "regulation of immune system process", "d": ["Any process that modulates the frequency, rate, or extent of an immune system process."], "t": []}], "preferred_name": "regulation of immune system process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:2001006", "l": "regulation of cellulose biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of cellulose biosynthetic process."], "t": []}], "preferred_name": "regulation of cellulose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000017", "l": "positive regulation of determination of dorsal identity", "d": ["Any process that activates or increases the frequency, rate or extent of determination of dorsal identity."], "t": []}], "preferred_name": "positive regulation of determination of dorsal identity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "70.189193548392481", "identifiers": [{"i": "GO:0008654", "l": "phospholipid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester."], "t": []}], "preferred_name": "phospholipid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2001050", "l": "negative regulation of tendon cell differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation."], "t": []}], "preferred_name": "negative regulation of tendon cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0000301", "l": "retrograde transport, vesicle recycling within Golgi", "d": ["The retrograde movement of substances within the Golgi, mediated by COP I vesicles. 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They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi."], "t": []}], "preferred_name": "retrograde transport, vesicle recycling within Golgi", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006115", "l": "ethanol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation."], "t": []}], "preferred_name": "ethanol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0046175", "l": "aldonic acid biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group."], "t": []}], "preferred_name": "aldonic acid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.588190044528119", "identifiers": [{"i": "GO:0006929", "l": "substrate-dependent cell migration", "d": ["The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate."], "t": []}], "preferred_name": "substrate-dependent cell migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0061212", "l": "mesonephric juxtaglomerular apparatus development", "d": ["The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate."], "t": []}], "preferred_name": "mesonephric juxtaglomerular apparatus development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0061536", "l": "glycine secretion", "d": ["The controlled release of glycine by a cell."], "t": []}], "preferred_name": "glycine secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0003133", "l": "endodermal-mesodermal cell signaling", "d": ["Any process that mediates the transfer of information from endodermal cells to mesodermal cells."], "t": []}], "preferred_name": "endodermal-mesodermal cell signaling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033389", "l": "putrescine biosynthetic process from arginine, using agmatinase", "d": ["The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step."], "t": []}], "preferred_name": "putrescine biosynthetic process from arginine, using agmatinase", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0048752", "l": "semicircular canal morphogenesis", "d": ["The process in which the anatomical structures of the semicircular canals are generated and organized."], "t": []}], "preferred_name": "semicircular canal morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1905778", "l": "negative regulation of exonuclease activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity."], "t": []}], "preferred_name": "negative regulation of exonuclease activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:2000128", "l": "regulation of octopamine signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of octopamine signaling pathway."], "t": []}], "preferred_name": "regulation of octopamine signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070462", "l": "plus-end specific microtubule depolymerization", "d": ["The removal of tubulin heterodimers from the plus end of a microtubule."], "t": []}], "preferred_name": "plus-end specific microtubule depolymerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042245", "l": "RNA repair", "d": ["Any process that results in the repair of damaged RNA."], "t": []}], "preferred_name": "RNA repair", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0039693", "l": "viral DNA genome replication", "d": ["The replication of a viral DNA genome."], "t": []}], "preferred_name": "viral DNA genome replication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000635", "l": "negative regulation of primary miRNA processing", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing."], "t": []}], "preferred_name": "negative regulation of primary miRNA processing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0043158", "l": "heterocyst development", "d": ["The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria."], "t": []}], "preferred_name": "heterocyst development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0050978", "l": "magnetoreception by sensory perception of electrical stimulus", "d": ["The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. 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Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew."], "t": []}], "preferred_name": "positive regulation of nematode larval development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0072322", "l": "protein transport across periplasmic space", "d": ["The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall."], "t": []}], "preferred_name": "protein transport across periplasmic space", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.928369586049996", "identifiers": [{"i": "GO:0007632", "l": "visual behavior", "d": ["The behavior of an organism in response to a visual stimulus."], "t": []}], "preferred_name": "visual behavior", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1990734", "l": "astral microtubule anchoring at mitotic spindle pole body", "d": ["Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. 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[{"i": "GO:2000672", "l": "negative regulation of motor neuron apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process."], "t": []}], "preferred_name": "negative regulation of motor neuron apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0016239", "l": "positive regulation of macroautophagy", "d": ["Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation."], "t": []}], "preferred_name": "positive regulation of macroautophagy", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035129", "l": "post-embryonic hindlimb morphogenesis", "d": ["The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized."], "t": []}], "preferred_name": "post-embryonic hindlimb morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905694", "l": "negative regulation of phosphatidic acid biosynthetic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process."], "t": []}], "preferred_name": "negative regulation of phosphatidic acid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071679", "l": "commissural neuron axon guidance", "d": ["The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues."], "t": []}], "preferred_name": "commissural neuron axon guidance", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0075016", "l": "appressorium 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The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins."], "t": []}], "preferred_name": "diterpene phytoalexin precursor biosynthetic process pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0001867", "l": "complement activation, lectin pathway", "d": ["Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."], "t": []}], "preferred_name": "complement activation, lectin pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0002239", "l": "response to oomycetes", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes."], "t": []}], "preferred_name": "response to oomycetes", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.928369586049996", "identifiers": [{"i": "GO:0006582", "l": "melanin metabolic process", "d": ["The chemical reactions and pathways involving melanins, pigments largely of animal origin. 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The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."], "t": []}], "preferred_name": "regulation of growth hormone receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140533", "l": "symbiont-mediated suppression of host RNAi-mediated antiviral immune response", "d": ["A process by which a symbiont inhibits or disrupts the host's RNAi-mediated antiviral immune response. 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Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. 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Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."], "t": []}], "preferred_name": "negative regulation of cell communication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0080113", "l": "regulation of seed growth", "d": ["Any process that modulates the frequency, rate or extent of growth of the seed of an plant."], "t": []}], "preferred_name": "regulation of seed growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:2000628", "l": "regulation of miRNA metabolic process", "d": ["Any process that modulates the frequency, rate or extent of miRNA metabolic process."], "t": []}], "preferred_name": "regulation of miRNA metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0006750", "l": "glutathione biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins."], "t": []}], "preferred_name": "glutathione biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018404", "l": "protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "d": ["Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues."], "t": []}], "preferred_name": "protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.685545702361054", "identifiers": [{"i": "GO:0061531", "l": "primary amine secretion", "d": ["The regulated release of a primary amine by a cell."], "t": []}], "preferred_name": "primary amine secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.110602442783048", "identifiers": [{"i": "GO:1903008", "l": "organelle disassembly", "d": ["The disaggregation of an organelle into its constituent components."], "t": []}], "preferred_name": "organelle disassembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099592", "l": "endocytosed synaptic vesicle processing via endosome", "d": ["The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles."], "t": []}], "preferred_name": "endocytosed synaptic vesicle processing via endosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002311", "l": "gamma-delta T cell proliferation involved in immune response", "d": ["The expansion of a gamma-delta T cell population by cell division as part of an immune response."], "t": []}], "preferred_name": "gamma-delta T cell proliferation involved in immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019356", "l": "nicotinate nucleotide biosynthetic process from tryptophan", "d": ["The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan."], "t": []}], "preferred_name": "nicotinate nucleotide biosynthetic process from tryptophan", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021504", "l": "neural fold hinge point formation", "d": ["The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube."], "t": []}], "preferred_name": "neural fold hinge point formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "63.813067021773541", "identifiers": [{"i": "GO:0031667", "l": "response to nutrient levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients."], "t": []}], "preferred_name": "response to nutrient levels", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0043376", "l": "regulation of CD8-positive, alpha-beta T cell differentiation", "d": ["Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell 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"positive regulation of heart induction", "d": ["Any process that activates or increases the frequency, rate or extent of heart induction."], "t": []}], "preferred_name": "positive regulation of heart induction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0061582", "l": "intestinal epithelial cell migration", "d": ["The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism."], "t": []}], "preferred_name": "intestinal epithelial cell migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000684", "l": "negative regulation of cellular response to X-ray", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray."], "t": []}], "preferred_name": "negative regulation of cellular response to X-ray", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900522", "l": "negative regulation of response to amylopectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin."], "t": []}], "preferred_name": "negative regulation of response to amylopectin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010350", "l": "cellular response to magnesium starvation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium."], "t": []}], "preferred_name": "cellular response to magnesium starvation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090391", "l": "granum assembly", "d": ["A process that is carried out at the cellular level which results in the assembly of a granum. 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It is an important intermediate in the biosynthesis of aromatic amino acids."], "t": []}], "preferred_name": "shikimate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140024", "l": "plus-end-directed endosome transport along mitotic spindle midzone microtubule", "d": ["The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. 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A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus."], "t": []}], "preferred_name": "intestinal epithelial cell maturation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060697", "l": "positive regulation of phospholipid catabolic process", "d": ["Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."], "t": []}], "preferred_name": "positive regulation of phospholipid catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0019392", "l": "glucarate metabolic process", "d": ["The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. 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A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels."], "t": []}], "preferred_name": "sodium-independent thromboxane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0046957", "l": "negative phototaxis", "d": ["The directed movement of a cell or organism away from a source of light."], "t": []}], "preferred_name": "negative phototaxis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062195", "l": "microtubule bundle maintenance", "d": ["The organization process that preserves a microtubule bundle in a stable functional or structural state."], "t": []}], "preferred_name": "microtubule bundle maintenance", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "37.384012917453241", "identifiers": [{"i": "GO:0050794", "l": "regulation of cellular process", "d": ["Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. 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A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin."], "t": []}], "preferred_name": "type B pancreatic cell fate commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0060156", "l": "milk ejection reflex", "d": ["A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. 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Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. 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This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis."], "t": []}], "preferred_name": "labial disc morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0060612", "l": "adipose tissue development", "d": ["The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. 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Some epothilones are being studied as treatments for cancer."], "t": []}], "preferred_name": "epothilone metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0072715", "l": "cellular response to selenite ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus."], "t": []}], "preferred_name": "cellular response to selenite ion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0033275", "l": "actin-myosin filament sliding", "d": ["The sliding movement of actin thin filaments and myosin thick filaments past each other."], "t": []}], "preferred_name": "actin-myosin filament sliding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.031767293544277", "identifiers": [{"i": "GO:0000578", "l": "embryonic axis specification", "d": ["The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo."], "t": []}], "preferred_name": "embryonic axis specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070710", "l": "RNA uridine deletion", "d": ["The modification of an RNA molecule by removal of a uridine nucleotide."], "t": []}], "preferred_name": "RNA uridine deletion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0048819", "l": "regulation of hair follicle maturation", "d": ["Any process that modulates the frequency, rate or extent of hair follicle maturation."], "t": []}], "preferred_name": "regulation of hair follicle maturation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0051887", "l": "regulation of timing of exogen", "d": ["Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle."], "t": []}], "preferred_name": "regulation of timing of exogen", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:2000547", "l": "regulation of dendritic cell dendrite assembly", "d": ["Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly."], "t": []}], "preferred_name": "regulation of dendritic cell dendrite assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141198", "l": "protein branched polyubiquitination", "d": ["A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at various positions of the ubiquitin monomers, forming branched linkages, such as K11/K48- or K11/K63-linked chains."], "t": []}], "preferred_name": "protein branched polyubiquitination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150071", "l": "negative regulation of arginase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity."], "t": []}], "preferred_name": "negative regulation of arginase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0002795", "l": "negative regulation of antimicrobial peptide secretion", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion."], "t": []}], "preferred_name": "negative regulation of antimicrobial peptide secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141145", "l": "symbiont-mediated suppression of host neutrophil extracellular trap formation", "d": ["A process in which a symbiont inhibits or disrupts the formation of neutrophil extracellular traps by the host cell. 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An example of this is found in Drosophila melanogaster."], "t": []}], "preferred_name": "growth of a germarium-derived egg chamber", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904890", "l": "negative regulation of excitatory synapse assembly", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly."], "t": []}], "preferred_name": "negative regulation of excitatory synapse assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0070631", "l": "spindle pole body localization", "d": ["Any process in which a spindle pole body is transported to, or maintained in, a specific location. 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It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."], "t": []}], "preferred_name": "pantothenate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0032459", "l": "regulation of protein oligomerization", "d": ["Any process that modulates the frequency, rate or extent of protein oligomerization."], "t": []}], "preferred_name": "regulation of protein oligomerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.9446391445248", "identifiers": [{"i": "GO:0043474", "l": "pigment metabolic process involved in pigmentation", "d": ["The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell."], "t": []}], "preferred_name": "pigment metabolic process involved in pigmentation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035206", "l": "regulation of hemocyte proliferation", "d": ["Any process that modulates the frequency, rate or extent of hemocyte proliferation. 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In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "preferred_name": "mitochondrial tyrosyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.825046931202166", "identifiers": [{"i": "GO:0015908", "l": "fatty acid transport", "d": ["The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Aminotriazole is an effective weed killer that also possesses some antithyroid activity."], "t": []}], "preferred_name": "aminotriazole transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.909793895370484", "identifiers": [{"i": "GO:0001763", "l": "morphogenesis of a branching structure", "d": ["The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. 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Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light."], "t": []}], "preferred_name": "magnetoreception", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.048036852019095", "identifiers": [{"i": "GO:0048521", "l": "negative regulation of behavior", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli."], "t": []}], "preferred_name": "negative regulation of behavior", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0019288", "l": "isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway", "d": ["The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. 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This process begins with the formation of kidney mesenchyme and ends with the mature structure. 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Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."], "t": []}], "preferred_name": "cellular response to vitamin B6", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0002298", "l": "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "d": ["The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response."], "t": []}], "preferred_name": "CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0044038", "l": "cell wall macromolecule biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall."], "t": []}], "preferred_name": "cell wall macromolecule biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0002816", "l": "regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "d": ["Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria."], "t": []}], "preferred_name": "regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0072716", "l": "response to actinomycin D", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus."], "t": []}], "preferred_name": "response to actinomycin D", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0150127", "l": "regulation of interleukin-33 production", "d": ["Any process that modulates the frequency, rate or extent of interleukin-33 production."], "t": []}], "preferred_name": "regulation of interleukin-33 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905542", "l": "negative regulation of L-arginine import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane."], "t": []}], "preferred_name": "negative regulation of L-arginine import across plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.9446391445248", "identifiers": [{"i": "GO:0032092", "l": "positive regulation of protein binding", "d": ["Any process that activates or increases the frequency, rate or extent of protein binding."], "t": []}], "preferred_name": "positive regulation of protein binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0048279", "l": "vesicle fusion with endoplasmic reticulum", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum."], "t": []}], "preferred_name": "vesicle fusion with endoplasmic reticulum", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035157", "l": "negative regulation of fusion cell fate specification", "d": ["Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. 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The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear."], "t": []}], "preferred_name": "lateral line ganglion development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098746", "l": "fast, calcium ion-dependent exocytosis of neurotransmitter", "d": ["The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release."], "t": []}], "preferred_name": "fast, calcium ion-dependent exocytosis of neurotransmitter", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0051904", "l": "pigment granule transport", "d": ["The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "preferred_name": "pigment granule transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903176", "l": "regulation of tyrosine 3-monooxygenase activity", "d": ["Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity."], "t": []}], "preferred_name": "regulation of tyrosine 3-monooxygenase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035020", "l": "regulation of Rac protein signal transduction", "d": ["Any process that modulates the frequency, rate or extent of Rac protein signal transduction."], "t": []}], "preferred_name": "regulation of Rac protein signal transduction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903102", "l": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate."], "t": []}], "preferred_name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0048903", "l": "anterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. 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This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch."], "t": []}], "preferred_name": "transcriptional attenuation by ribosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0070304", "l": "positive regulation of stress-activated protein kinase signaling cascade", "d": ["Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade."], "t": []}], "preferred_name": "positive regulation of stress-activated protein kinase signaling cascade", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009650", "l": "UV protection", "d": ["Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV."], "t": []}], "preferred_name": "UV protection", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.028704465244275", "identifiers": [{"i": "GO:0030537", "l": "larval behavior", "d": ["Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics."], "t": []}], "preferred_name": "larval behavior", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045339", "l": "farnesyl diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate."], "t": []}], "preferred_name": "farnesyl diphosphate catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0002074", "l": "extraocular skeletal muscle development", "d": ["The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. 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An example of this process is found in Mus musculus."], "t": []}], "preferred_name": "extraocular skeletal muscle development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0018898", "l": "2,4-dichlorobenzoate metabolic process", "d": ["The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs)."], "t": []}], "preferred_name": "2,4-dichlorobenzoate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0080186", "l": "developmental vegetative growth", "d": ["The increase in size or mass of non-reproductive plant parts."], "t": []}], "preferred_name": "developmental vegetative growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:2000527", "l": "regulation of myeloid 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Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."], "t": []}], "preferred_name": "pyridoxamine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.36074427942161", "identifiers": [{"i": "GO:0071715", "l": "icosanoid transport", "d": ["The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. 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The bud elongates and branches to give rise to the ureter and kidney collecting tubules."], "t": []}], "preferred_name": "branching involved in ureteric bud morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0090507", "l": "phenylethylamine metabolic process involved in synaptic transmission", "d": ["The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission."], "t": []}], "preferred_name": "phenylethylamine metabolic process involved in synaptic transmission", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0006041", "l": "glucosamine metabolic process", "d": ["The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin."], "t": []}], "preferred_name": "glucosamine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0002238", "l": "response to molecule of fungal origin", "d": ["Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide."], "t": []}], "preferred_name": "response to molecule of fungal origin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0075270", "l": "negative regulation of aecium development", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed."], "t": []}], "preferred_name": "negative regulation of aecium development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0042976", "l": "activation of Janus kinase activity", "d": ["The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it."], "t": []}], "preferred_name": "activation of Janus kinase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0051941", "l": "regulation of amino acid uptake involved in synaptic transmission", "d": ["Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell."], "t": []}], "preferred_name": "regulation of amino acid uptake involved in synaptic transmission", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901741", "l": "positive regulation of myoblast fusion", "d": ["Any process that activates or increases the frequency, rate or extent of myoblast fusion."], "t": []}], "preferred_name": "positive regulation of myoblast fusion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0007296", "l": "vitellogenesis", "d": ["The production of yolk. 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Larger structures are transported along microtubules to the cis-Golgi."], "t": []}], "preferred_name": "regulation of ER to Golgi vesicle-mediated transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.601480381641593", "identifiers": [{"i": "GO:0051305", "l": "chromosome movement towards spindle pole", "d": ["The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes."], "t": []}], "preferred_name": "chromosome movement towards spindle pole", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090362", "l": "positive regulation of platelet-derived growth factor production", "d": ["Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels."], "t": []}], "preferred_name": "positive regulation of platelet-derived growth factor production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0042672", "l": "retinal cone cell fate specification", "d": ["The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed."], "t": []}], "preferred_name": "retinal cone cell fate specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "55.905667755195175", "identifiers": [{"i": "GO:0033554", "l": "cellular response to stress", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. 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They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle."], "t": []}], "preferred_name": "lateral ventricle development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0034139", "l": "regulation of toll-like receptor 3 signaling pathway", "d": ["Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway."], "t": []}], "preferred_name": "regulation of toll-like receptor 3 signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099157", "l": "trans-synaptic signaling via exosome", "d": ["Transynaptic signaling in which the ligand is carried across the synapse by an exosome."], "t": []}], "preferred_name": "trans-synaptic signaling via exosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097069", "l": "cellular response to thyroxine stimulus", "d": ["A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus."], "t": []}], "preferred_name": "cellular response to thyroxine stimulus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0098911", "l": "regulation of ventricular cardiac muscle cell action potential", "d": ["Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. 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The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism."], "t": []}], "preferred_name": "biological process involved in interaction with symbiont", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1901975", "l": "glycerate transmembrane transport", "d": ["The process in which glycerate is transported across a membrane."], "t": []}], "preferred_name": "glycerate transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0046463", "l": "acylglycerol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."], "t": []}], "preferred_name": "acylglycerol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0033356", "l": "UDP-L-arabinose metabolic process", "d": ["The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate."], "t": []}], "preferred_name": "UDP-L-arabinose metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0045961", "l": "negative regulation of development, heterochronic", "d": ["Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached."], "t": []}], "preferred_name": "negative regulation of development, heterochronic", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.950626012100827", "identifiers": [{"i": "GO:0007286", "l": "spermatid development", "d": ["The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure."], "t": []}], "preferred_name": "spermatid development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.588190044528119", "identifiers": [{"i": "GO:0061780", "l": "mitotic cohesin loading", "d": ["The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle."], "t": []}], "preferred_name": "mitotic cohesin loading", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0009137", "l": "purine nucleoside diphosphate catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar."], "t": []}], "preferred_name": "purine nucleoside diphosphate catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060376", "l": "positive regulation of mast cell differentiation", "d": ["Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. 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An example of this process is found in Arabidopsis thaliana."], "t": []}], "preferred_name": "embryo sac cellularization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1901125", "l": "candicidin metabolic process", "d": ["The chemical reactions and pathways involving candicidin."], "t": []}], "preferred_name": "candicidin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097552", "l": "mitochondrial double-strand break repair via homologous recombination", "d": ["The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences."], "t": []}], "preferred_name": "mitochondrial double-strand break repair via homologous recombination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.800420664837461", "identifiers": [{"i": "GO:0072017", "l": "distal tubule development", "d": ["The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. 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The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi."], "t": []}], "preferred_name": "regulation of basidium development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0006795", "l": "regulation of phosphorus utilization", "d": ["Any process that modulates the frequency, rate or extent of phosphorus utilization."], "t": []}], "preferred_name": "regulation of phosphorus utilization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070143", "l": "mitochondrial alanyl-tRNA aminoacylation", "d": ["The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. 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A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin."], "t": []}], "preferred_name": "prolactin secreting cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061132", "l": "pancreas induction", "d": ["The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas."], "t": []}], "preferred_name": "pancreas induction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0045827", "l": "negative regulation of isoprenoid metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid."], "t": []}], "preferred_name": "negative regulation of isoprenoid metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0106007", "l": "microtubule anchoring at cell cortex of cell tip", "d": ["Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex."], "t": []}], "preferred_name": "microtubule anchoring at cell cortex of cell tip", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0034982", "l": "mitochondrial protein processing", "d": ["The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import."], "t": []}], "preferred_name": "mitochondrial protein processing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032715", "l": "negative regulation of interleukin-6 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production."], "t": []}], "preferred_name": "negative regulation of interleukin-6 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0090245", "l": "axis elongation involved in somitogenesis", "d": ["The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis."], "t": []}], "preferred_name": "axis elongation involved in somitogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0038010", "l": "positive regulation of signal transduction by receptor internalization", "d": ["Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. 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This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine."], "t": []}], "preferred_name": "lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0048816", "l": "ocellus morphogenesis", "d": ["The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects."], "t": []}], "preferred_name": "ocellus morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902748", "l": "positive regulation of lens fiber cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation."], "t": []}], "preferred_name": "positive regulation of lens fiber cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019504", "l": "L-proline betaine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline."], "t": []}], "preferred_name": "L-proline betaine catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "59.886706052834484", "identifiers": [{"i": "GO:0006396", "l": "RNA processing", "d": ["Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules."], "t": []}], "preferred_name": "RNA processing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007111", "l": "meiosis II cytokinesis", "d": ["A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells."], "t": []}], "preferred_name": "meiosis II cytokinesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140060", "l": "axon arborization", "d": ["The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches."], "t": []}], "preferred_name": "axon arborization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905070", "l": "anterior visceral endoderm cell migration", "d": ["The orderly movement of an anterior visceral endoderm cell from one site to another."], "t": []}], "preferred_name": "anterior visceral endoderm cell migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099015", "l": "degradation of host chromosome by virus", "d": ["The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis."], "t": []}], "preferred_name": "degradation of host chromosome by virus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "62.688717954073617", "identifiers": [{"i": "GO:0019724", "l": "B cell mediated immunity", "d": ["Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells."], "t": []}], "preferred_name": "B cell mediated immunity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000065", "l": "negative regulation of cortisol biosynthetic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process."], "t": []}], "preferred_name": "negative regulation of cortisol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901290", "l": "succinyl-CoA biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of succinyl-CoA."], "t": []}], "preferred_name": "succinyl-CoA biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0106220", "l": "pyocyanine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group."], "t": []}], "preferred_name": "pyocyanine biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0019523", "l": "L-idonate metabolic process", "d": ["The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."], "t": []}], "preferred_name": "L-idonate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900059", "l": "positive regulation of sulfate assimilation", "d": ["Any process that activates or increases the frequency, rate or extent of sulfate assimilation."], "t": []}], "preferred_name": "positive regulation of sulfate assimilation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904571", "l": "positive regulation of selenocysteine incorporation", "d": ["Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation."], "t": []}], "preferred_name": "positive regulation of selenocysteine incorporation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0032084", "l": "regulation of type I site-specific deoxyribonuclease activity", "d": ["Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity."], "t": []}], "preferred_name": "regulation of type I site-specific deoxyribonuclease activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032708", "l": "negative regulation of interleukin-24 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production."], "t": []}], "preferred_name": "negative regulation of interleukin-24 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0052034", "l": "effector-mediated suppression of host pattern-triggered immunity", "d": ["A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "effector-mediated suppression of host pattern-triggered immunity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061257", "l": "mesonephric podocyte development", "d": ["The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros."], "t": []}], "preferred_name": "mesonephric podocyte development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000297", "l": "negative regulation of synapse maturation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation."], "t": []}], "preferred_name": "negative regulation of synapse maturation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0110105", "l": "mRNA cleavage and polyadenylation specificity factor complex assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex."], "t": []}], "preferred_name": "mRNA cleavage and polyadenylation specificity factor complex assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0048711", "l": "positive regulation of astrocyte differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of astrocyte differentiation."], "t": []}], "preferred_name": "positive regulation of astrocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0035167", "l": "larval lymph gland hemopoiesis", "d": ["The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages."], "t": []}], "preferred_name": "larval lymph gland hemopoiesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0045844", "l": "positive regulation of striated muscle tissue development", "d": ["Any process that activates or increases the frequency, rate or extent of striated muscle development."], "t": []}], "preferred_name": "positive regulation of striated muscle tissue development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019256", "l": "acrylonitrile catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers."], "t": []}], "preferred_name": "acrylonitrile catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0060353", "l": "regulation of cell adhesion molecule production", "d": ["Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism."], "t": []}], "preferred_name": "regulation of cell adhesion molecule production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0010992", "l": "ubiquitin recycling", "d": ["Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates."], "t": []}], "preferred_name": "ubiquitin recycling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000811", "l": "negative regulation of anoikis", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of anoikis."], "t": []}], "preferred_name": "negative regulation of anoikis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044205", "l": "'de novo' UMP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen."], "t": []}], "preferred_name": "'de novo' UMP biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0045003", "l": "double-strand break repair via synthesis-dependent strand annealing", "d": ["SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."], "t": []}], "preferred_name": "double-strand break repair via synthesis-dependent strand annealing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0006070", "l": "octanol metabolic process", "d": ["The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH."], "t": []}], "preferred_name": "octanol metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0021636", "l": "trigeminal nerve morphogenesis", "d": ["The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae."], "t": []}], "preferred_name": "trigeminal nerve morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021729", "l": "superior reticular formation development", "d": ["The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure."], "t": []}], "preferred_name": "superior reticular formation development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0097281", "l": "immune complex formation", "d": ["The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus."], "t": []}], "preferred_name": "immune complex formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042187", "l": "p-xylene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon."], "t": []}], "preferred_name": "p-xylene catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "46.262586338623812", "identifiers": [{"i": "GO:0015711", "l": "organic anion transport", "d": ["The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."], "t": []}], "preferred_name": "organic anion transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.721147647610692", "identifiers": [{"i": "GO:0042713", "l": "sperm ejaculation", "d": ["The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract."], "t": []}], "preferred_name": "sperm ejaculation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0032065", "l": "maintenance of protein location in cell cortex", "d": ["A process in which a protein or protein complex is maintained in a specific location in the cell cortex."], "t": []}], "preferred_name": "maintenance of protein location in cell cortex", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0019087", "l": "transformation of host cell by virus", "d": ["A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication."], "t": []}], "preferred_name": "transformation of host cell by virus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0101027", "l": "optical nerve axon regeneration", "d": ["The regrowth of axons of the optical nerve following their loss or damage."], "t": []}], "preferred_name": "optical nerve axon regeneration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0016095", "l": "polyprenol catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans."], "t": []}], "preferred_name": "polyprenol catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0014719", "l": "skeletal muscle satellite cell activation", "d": ["The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage."], "t": []}], "preferred_name": "skeletal muscle satellite cell activation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097436", "l": "entry into dormancy", "d": ["The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated."], "t": []}], "preferred_name": "entry into dormancy", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0070459", "l": "prolactin secretion", "d": ["The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary."], "t": []}], "preferred_name": "prolactin secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120142", "l": "positive regulation of ecdysone receptor signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of any ecdysone receptor signaling pathway."], "t": []}], "preferred_name": "positive regulation of ecdysone receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0015779", "l": "glucuronoside transport", "d": ["The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate."], "t": []}], "preferred_name": "glucuronoside transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0006554", "l": "lysine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid."], "t": []}], "preferred_name": "lysine catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007388", "l": "posterior compartment specification", "d": ["The process involved in the specification of cell identity in the posterior compartments of the segmented embryo."], "t": []}], "preferred_name": "posterior compartment specification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:0060444", "l": "branching involved in mammary gland duct morphogenesis", "d": ["The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk."], "t": []}], "preferred_name": "branching involved in mammary gland duct morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0009454", "l": "aerotaxis", "d": ["The directed movement of a motile cell or organism in response to environmental oxygen."], "t": []}], "preferred_name": "aerotaxis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0031652", "l": "positive regulation of heat generation", "d": ["Any process that activates or increases the rate or extent of heat generation."], "t": []}], "preferred_name": "positive regulation of heat generation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0075029", "l": "formation of appressorium germ tube hook structure", "d": ["The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation."], "t": []}], "preferred_name": "formation of appressorium germ tube hook structure", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0030837", "l": "negative regulation of actin filament polymerization", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization."], "t": []}], "preferred_name": "negative regulation of actin filament polymerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0010974", "l": "negative regulation of division septum assembly", "d": ["Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis."], "t": []}], "preferred_name": "negative regulation of division septum assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032686", "l": "negative regulation of hepatocyte growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production."], "t": []}], "preferred_name": "negative regulation of hepatocyte growth factor production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.271528348933202", "identifiers": [{"i": "GO:0002062", "l": "chondrocyte differentiation", "d": ["The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage."], "t": []}], "preferred_name": "chondrocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032150", "l": "ubiquinone biosynthetic process from chorismate", "d": ["The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate."], "t": []}], "preferred_name": "ubiquinone biosynthetic process from chorismate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.601480381641593", "identifiers": [{"i": "GO:0060457", "l": "negative regulation of digestive system process", "d": ["Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism."], "t": []}], "preferred_name": "negative regulation of digestive system process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0018891", "l": "cyclohexanol metabolic process", "d": ["The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. 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"GO:1902890", "l": "regulation of root hair elongation", "d": ["Any process that modulates the frequency, rate or extent of root hair elongation."], "t": []}], "preferred_name": "regulation of root hair elongation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018389", "l": "N-terminal peptidyl-valine deamination", "d": ["The deamination of the N-terminal valine residue of a protein to form isobutyrate."], "t": []}], "preferred_name": "N-terminal peptidyl-valine deamination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060177", "l": "regulation of angiotensin metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin."], "t": []}], "preferred_name": "regulation of angiotensin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0033258", "l": "plastid DNA metabolic process", "d": ["The chemical reactions and pathways involving plastid DNA."], "t": []}], "preferred_name": "plastid DNA metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032683", "l": "negative regulation of connective tissue growth factor production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production."], "t": []}], "preferred_name": "negative regulation of connective tissue growth factor production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "56.199471411532478", "identifiers": [{"i": "GO:0008219", "l": "cell death", "d": ["Any biological process that results in permanent cessation of all vital functions of a cell. 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The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."], "t": []}], "preferred_name": "positive regulation of cleistothecium development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0140216", "l": "negative regulation of D-aspartate import across plasma membrane", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol."], "t": []}], "preferred_name": "negative regulation of D-aspartate import across plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046258", "l": "anaerobic 2,4,6-trinitrotoluene catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen."], "t": []}], "preferred_name": "anaerobic 2,4,6-trinitrotoluene catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.203526930956613", "identifiers": [{"i": "GO:0019217", "l": "regulation of fatty acid metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids."], "t": []}], "preferred_name": "regulation of fatty acid metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1990670", "l": "vesicle fusion with Golgi cis cisterna membrane", "d": ["The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. 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This process pertains to the initial formation of a structure from unspecified parts."], "t": []}], "preferred_name": "floral whorl formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.479506983467815", "identifiers": [{"i": "GO:0051345", "l": "positive regulation of hydrolase activity", "d": ["Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds."], "t": []}], "preferred_name": "positive regulation of hydrolase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0061113", "l": "pancreas morphogenesis", "d": ["Morphogenesis of the pancreas. 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The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."], "t": []}], "preferred_name": "mannose metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.090052188295473", "identifiers": [{"i": "GO:0045980", "l": "negative regulation of nucleotide metabolic process", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides."], "t": []}], "preferred_name": "negative regulation of nucleotide metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018956", "l": "phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene", "d": ["The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite."], "t": []}], "preferred_name": "phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1900872", "l": "pentadec-1-ene metabolic process", "d": ["The chemical reactions and pathways involving pentadec-1-ene."], "t": []}], "preferred_name": "pentadec-1-ene metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002289", "l": "NK T cell proliferation involved in immune response", "d": ["The expansion of a NK T cell population by cell division as part of an immune response."], "t": []}], "preferred_name": "NK T cell proliferation involved in immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044029", "l": "positive regulation of gene expression via chromosomal CpG island demethylation", "d": ["An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. 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Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer."], "t": []}], "preferred_name": "protein heterooligomerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:0009395", "l": "phospholipid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester."], "t": []}], "preferred_name": "phospholipid catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.840291904755873", "identifiers": [{"i": "GO:0006400", "l": "tRNA modification", "d": ["The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically."], "t": []}], "preferred_name": "tRNA modification", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045469", "l": "negative regulation of R8 cell spacing in compound eye", "d": ["Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye."], "t": []}], "preferred_name": "negative regulation of R8 cell spacing in compound eye", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071309", "l": "cellular response to phylloquinone", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus."], "t": []}], "preferred_name": "cellular response to phylloquinone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0018352", "l": "protein-pyridoxal-5-phosphate linkage", "d": ["The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate."], "t": []}], "preferred_name": "protein-pyridoxal-5-phosphate linkage", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0051986", "l": "negative regulation of attachment of spindle microtubules to kinetochore", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore."], "t": []}], "preferred_name": "negative regulation of attachment of spindle microtubules to kinetochore", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031318", "l": "detection of folic acid", "d": ["The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal."], "t": []}], "preferred_name": "detection of folic acid", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904437", "l": "positive regulation of transferrin receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of transferrin receptor binding."], "t": []}], "preferred_name": "positive regulation of transferrin receptor binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0007630", "l": "jump response", "d": ["The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus."], "t": []}], "preferred_name": "jump response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.048036852019095", "identifiers": [{"i": "GO:0009124", "l": "nucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar."], "t": []}], "preferred_name": "nucleoside monophosphate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905388", "l": "cellular response to beta-carotene", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus."], "t": []}], "preferred_name": "cellular response to beta-carotene", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0021769", "l": "orbitofrontal cortex development", "d": ["The progression of the orbitofrontal cortex over time from its initial formation until its mature state. 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Cell development does not include the steps involved in committing a cell to a specific fate."], "t": []}], "preferred_name": "neuromast hair cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0044575", "l": "cellulosome assembly", "d": ["The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall."], "t": []}], "preferred_name": "cellulosome assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000860", "l": "positive regulation of aldosterone secretion", "d": ["Any process that activates or increases the frequency, rate or extent of aldosterone secretion."], "t": []}], "preferred_name": "positive regulation of aldosterone secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0032689", "l": "negative regulation of type II interferon production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. 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"preferred_name": "negative regulation of defecation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900832", "l": "D-leucine catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of D-leucine."], "t": []}], "preferred_name": "D-leucine catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.25002861897768", "identifiers": [{"i": "GO:0072655", "l": "establishment of protein localization to mitochondrion", "d": ["The directed movement of a protein to the mitochondrion or a part of the mitochondrion."], "t": []}], "preferred_name": "establishment of protein localization to mitochondrion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0033319", "l": "UDP-D-xylose metabolic process", "d": ["The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with 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The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter."], "t": []}], "preferred_name": "posterior lateral line neuromast cupula development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0031285", "l": "regulation of sorocarp stalk cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum."], "t": []}], "preferred_name": "regulation of sorocarp stalk cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0061107", "l": "seminal vesicle development", "d": ["The progression of the seminal vesicle over time, from its formation to the mature structure. 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The massive cytokine release can lead to an acute toxic shock, causing symptoms such as fever and organ damage."], "t": []}], "preferred_name": "symbiont-mediated non-specific activation of host T-cells", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901786", "l": "p-cresol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of p-cresol."], "t": []}], "preferred_name": "p-cresol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0030649", "l": "aminoglycoside antibiotic catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. 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Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included."], "t": []}], "preferred_name": "organic phosphonate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0035292", "l": "specification of segmental identity, trunk", "d": ["The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. 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This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen."], "t": []}], "preferred_name": "symbiont entry into host cell via permeabilization of endosomal membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1902994", "l": "regulation of phospholipid efflux", "d": ["Any process that modulates the frequency, rate or extent of phospholipid efflux."], "t": []}], "preferred_name": "regulation of phospholipid efflux", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090038", "l": "negative regulation of protein kinase C signaling", "d": ["Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound."], "t": []}], "preferred_name": "negative regulation of protein kinase C signaling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0071873", "l": "response to norepinephrine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. 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They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. 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The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle."], "t": []}], "preferred_name": "oculomotor nerve formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0044553", "l": "modulation of biological quality in another organism", "d": ["Any process that modulates the frequency, rate or extent of a biological quality in another organism. 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This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located."], "t": []}], "preferred_name": "adhesion receptor-mediated virion attachment to host cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0045602", "l": "negative regulation of endothelial cell differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation."], "t": []}], "preferred_name": "negative regulation of endothelial cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0014916", "l": "regulation of lung blood pressure", "d": ["The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure."], "t": []}], "preferred_name": "regulation of lung blood pressure", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0010346", "l": "shoot axis formation", "d": ["The process that gives rise to a shoot axis. 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Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."], "t": []}], "preferred_name": "regulation of cholesterol storage", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.162719951716028", "identifiers": [{"i": "GO:0009611", "l": "response to wounding", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism."], "t": []}], "preferred_name": "response to wounding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097097", "l": "nasal suture morphogenesis", "d": ["The process in which the nasal suture is generated and organized."], "t": []}], "preferred_name": "nasal suture morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033480", "l": "UDP-D-galacturonate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate."], "t": []}], "preferred_name": "UDP-D-galacturonate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0046075", "l": "dTTP metabolic process", "d": ["The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate."], "t": []}], "preferred_name": "dTTP metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0030206", "l": "chondroitin sulfate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate."], "t": []}], "preferred_name": "chondroitin sulfate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141063", "l": "epigenetic programming in the central cell", "d": ["The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "positive regulation of arbuscule formation for nutrient acquisition from host", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1990036", "l": "calcium ion import into sarcoplasmic reticulum", "d": ["The directed movement of calcium ions into a sarcoplasmic reticulum."], "t": []}], "preferred_name": "calcium ion import into sarcoplasmic reticulum", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990403", "l": "embryonic brain development", "d": ["The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure."], "t": []}], "preferred_name": "embryonic brain development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0014827", "l": "intestine smooth muscle contraction", "d": ["A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. 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In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes."], "t": []}], "preferred_name": "vulval cell fate determination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0009157", "l": "deoxyribonucleoside monophosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar."], "t": []}], "preferred_name": "deoxyribonucleoside monophosphate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1904990", "l": "regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "d": ["Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway."], "t": []}], "preferred_name": "regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0072681", "l": "fibronectin-dependent thymocyte migration", "d": ["The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix."], "t": []}], "preferred_name": "fibronectin-dependent thymocyte migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000570", "l": "positive regulation of T-helper 2 cell activation", "d": ["Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation."], "t": []}], "preferred_name": "positive regulation of T-helper 2 cell activation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0071699", "l": "olfactory placode morphogenesis", "d": ["The process in which the anatomical structures of the olfactory placode are generated and organized. 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Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite."], "t": []}], "preferred_name": "aerobic ammonia oxidation to nitrite via pyruvic oxime", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903197", "l": "positive regulation of L-dopa biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process."], "t": []}], "preferred_name": "positive regulation of L-dopa biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051629", "l": "inhibition of epinephrine uptake", "d": ["Any process that prevents the activation of the directed movement of epinephrine into a cell."], "t": []}], "preferred_name": "inhibition of epinephrine uptake", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.892341117349616", "identifiers": [{"i": "GO:0061005", "l": "cell differentiation involved in kidney development", "d": ["The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state."], "t": []}], "preferred_name": "cell differentiation involved in kidney development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045775", "l": "positive regulation of beta 2 integrin biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins."], "t": []}], "preferred_name": "positive regulation of beta 2 integrin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0044527", "l": "formation of peptidyl-cystine persulfide by sulphur transfer from H2S", "d": ["The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide."], "t": []}], "preferred_name": "formation of peptidyl-cystine persulfide by sulphur transfer from H2S", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0071468", "l": "cellular response to acidic pH", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution."], "t": []}], "preferred_name": "cellular response to acidic pH", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060682", "l": "primary ureteric bud growth", "d": ["The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema."], "t": []}], "preferred_name": "primary ureteric bud growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050887", "l": "determination of sensory modality", "d": ["The determination of the type or quality of a sensation. 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This is distinct from maintenance of cellular homeostasis, which occurs within a cell."], "t": []}], "preferred_name": "multicellular organismal-level iron ion homeostasis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0036071", "l": "N-glycan fucosylation", "d": ["The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains."], "t": []}], "preferred_name": "N-glycan fucosylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0032599", "l": "protein transport out of membrane raft", "d": ["The directed movement of a protein out of a membrane raft. 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This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ."], "t": []}], "preferred_name": "swim bladder formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098672", "l": "symbiont-mediated suppression of host CRISPR-cas system", "d": ["A process by which a symbiont inhibits or disrupts the CRISPR-cas system of its host. 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Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. 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Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom."], "t": []}], "preferred_name": "amine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0051103", "l": "DNA ligation involved in DNA repair", "d": ["The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair."], "t": []}], "preferred_name": "DNA ligation involved in DNA repair", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090551", "l": "response to manganese starvation", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese."], "t": []}], "preferred_name": "response to manganese starvation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010620", "l": "negative regulation of transcription by transcription factor catabolism", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome."], "t": []}], "preferred_name": "negative regulation of transcription by transcription factor catabolism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1905864", "l": "regulation of Atg1/ULK1 kinase complex assembly", "d": ["Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly."], "t": []}], "preferred_name": "regulation of Atg1/ULK1 kinase complex assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0099148", "l": "regulation of synaptic vesicle docking", "d": ["Any process that modulates the frequency, rate or extent of synaptic vesicle docking."], "t": []}], "preferred_name": "regulation of synaptic vesicle docking", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "69.444611027361191", "identifiers": [{"i": "GO:0031109", "l": "microtubule polymerization or depolymerization", "d": ["Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule."], "t": []}], "preferred_name": "microtubule polymerization or depolymerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071639", "l": "positive regulation of monocyte chemotactic protein-1 production", "d": ["Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1."], "t": []}], "preferred_name": "positive regulation of monocyte chemotactic protein-1 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098676", "l": "modulation of host virulence by virus", "d": ["A process by which a virus improves the virulence of its host for that host's respective host. 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The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments."], "t": []}], "preferred_name": "rhabdomere development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.580844850107752", "identifiers": [{"i": "GO:0035738", "l": "envenomation resulting in modulation of process in another organism", "d": ["The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism."], "t": []}], "preferred_name": "envenomation resulting in modulation of process in another organism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0033067", "l": "macrolide metabolic process", "d": ["The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. 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This pathway is often associated with maintaining homeostasis in endocrine and exocrine cells."], "t": []}], "preferred_name": "crinophagy", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:2000051", "l": "negative regulation of non-canonical Wnt signaling pathway", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway."], "t": []}], "preferred_name": "negative regulation of non-canonical Wnt signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905904", "l": "positive regulation of mesoderm formation", "d": ["Any process that activates or increases the frequency, rate or extent of mesoderm formation."], "t": []}], "preferred_name": "positive regulation of mesoderm formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006973", "l": "intracellular accumulation of glycerol", "d": ["The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment."], "t": []}], "preferred_name": "intracellular accumulation of glycerol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905451", "l": "positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "d": ["Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis."], "t": []}], "preferred_name": "positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.517524484334686", "identifiers": [{"i": "GO:0033262", "l": "regulation of nuclear cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."], "t": []}], "preferred_name": "regulation of nuclear cell cycle DNA replication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902283", "l": "negative regulation of primary amine oxidase activity", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity."], "t": []}], "preferred_name": "negative regulation of primary amine oxidase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903934", "l": "positive regulation of DNA primase activity", "d": ["Any process that activates or increases the frequency, rate or extent of DNA primase activity."], "t": []}], "preferred_name": "positive regulation of DNA primase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021677", "l": "rhombomere 8 formation", "d": ["The process that gives rise to rhombomere 8. 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Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. 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It is highly toxic and harmful in contact with skin."], "t": []}], "preferred_name": "benzonitrile metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006191", "l": "deoxyinosine salvage", "d": ["Any process that generates deoxyinosine from derivatives of it, without de novo synthesis."], "t": []}], "preferred_name": "deoxyinosine salvage", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1904212", "l": "regulation of iodide transmembrane transport", "d": ["Any process that modulates the frequency, rate or extent of iodide transmembrane transport."], "t": []}], "preferred_name": "regulation of iodide transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0000712", "l": "resolution of meiotic recombination intermediates", "d": ["The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged."], "t": []}], "preferred_name": "resolution of meiotic recombination intermediates", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0050820", "l": "positive regulation of coagulation", "d": ["Any process that activates or increases the frequency, rate or extent of coagulation."], "t": []}], "preferred_name": "positive regulation of coagulation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0035862", "l": "dITP metabolic process", "d": ["The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position."], "t": []}], "preferred_name": "dITP metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000521", "l": "negative regulation of immunological synapse formation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation."], "t": []}], "preferred_name": "negative regulation of immunological synapse formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0006895", "l": "Golgi to endosome transport", "d": ["The directed movement of substances from the Golgi to early sorting endosomes. 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Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively."], "t": []}], "preferred_name": "7-methylguanosine mRNA capping", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0061250", "l": "mesonephric glomerular epithelial cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. 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A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "preferred_name": "myoblast fusion involved in skeletal muscle regeneration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106036", "l": "assembly of apicomedial cortex actomyosin", "d": ["A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin."], "t": []}], "preferred_name": "assembly of apicomedial cortex actomyosin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0007482", "l": "haltere development", "d": ["The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings."], "t": []}], "preferred_name": "haltere development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:2000277", "l": "positive regulation of oxidative phosphorylation uncoupler activity", "d": ["Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity."], "t": []}], "preferred_name": "positive regulation of oxidative phosphorylation uncoupler activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.680315530880364", "identifiers": [{"i": "GO:0000087", "l": "mitotic M phase", "d": ["A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle."], "t": []}], "preferred_name": "mitotic M phase", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:1901800", "l": 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For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects."], "t": []}], "preferred_name": "response to pulsatile fluid shear stress", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0019095", "l": "pole plasm mitochondrial rRNA localization", "d": ["Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. 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Also found in plants."], "t": []}], "preferred_name": "progesterone biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021650", "l": "vestibulocochlear nerve formation", "d": ["The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea."], "t": []}], "preferred_name": "vestibulocochlear nerve formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120265", "l": "negative regulation of chromosome attachment to the nuclear envelope", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope."], "t": []}], "preferred_name": "negative regulation of chromosome attachment to the nuclear envelope", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.721147647610692", "identifiers": [{"i": "GO:0055017", "l": "cardiac muscle tissue growth", "d": ["The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another."], "t": []}], "preferred_name": "cardiac muscle tissue growth", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0035457", "l": "cellular response to interferon-alpha", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon."], "t": []}], "preferred_name": "cellular response to interferon-alpha", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045794", "l": "negative regulation of cell volume", "d": ["Any process that decreases cell volume."], "t": []}], "preferred_name": "negative regulation of cell volume", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0034051", "l": "negative regulation of plant-type hypersensitive response", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant."], "t": []}], "preferred_name": "negative regulation of plant-type hypersensitive response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0072215", "l": "regulation of metanephros development", "d": ["Any process that modulates the rate, frequency or extent of metanephros development. 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The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine."], "t": []}], "preferred_name": "regulation of metanephros development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0002345", "l": "peripheral B cell receptor editing", "d": ["The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation."], "t": []}], "preferred_name": "peripheral B cell receptor editing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097338", "l": "response to clozapine", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus."], "t": []}], "preferred_name": "response to clozapine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0048360", "l": "root cap mucilage metabolic process", "d": ["The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth."], "t": []}], "preferred_name": "root cap mucilage metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070958", "l": "negative regulation of neutrophil mediated killing of gram-positive bacterium", "d": ["Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil."], "t": []}], "preferred_name": "negative regulation of neutrophil mediated killing of gram-positive bacterium", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1905012", "l": "regulation of 'de novo' NAD biosynthetic process from tryptophan", "d": ["Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan."], "t": []}], "preferred_name": "regulation of 'de novo' NAD biosynthetic process from tryptophan", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009442", "l": "allantoin assimilation pathway", "d": ["The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. 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This may then be further metabolized to CO2, NH4+ and ATP."], "t": []}], "preferred_name": "allantoin assimilation pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901330", "l": "negative regulation of odontoblast differentiation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation."], "t": []}], "preferred_name": "negative regulation of odontoblast differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061782", "l": "vesicle fusion with vesicle", "d": ["Fusion of the membrane of a transport vesicle with a target membrane on another vesicle."], "t": []}], "preferred_name": "vesicle fusion with vesicle", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904087", "l": "negative regulation of epiboly involved in gastrulation with mouth forming second", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second."], "t": []}], "preferred_name": "negative regulation of epiboly involved in gastrulation with mouth forming second", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0039678", "l": "symbiont genome ejection through host cell envelope", "d": ["Entry of a symbiont's genome into the host cell through the host cell envelope. Occurs in non-enveloped prokaryotic viruses. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm."], "t": []}], "preferred_name": "symbiont genome ejection through host cell envelope", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.382780109870865", "identifiers": [{"i": "GO:0002573", "l": "myeloid leukocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage."], "t": []}], "preferred_name": "myeloid leukocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0044831", "l": "modulation by virus of host cytokine production", "d": ["Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism."], "t": []}], "preferred_name": "modulation by virus of host cytokine production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:1905145", "l": "cellular response to acetylcholine", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus."], "t": []}], "preferred_name": "cellular response to acetylcholine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0072325", "l": "vulval cell fate commitment", "d": ["The process in which the cellular identity of nematode vulval cells is acquired and determined. 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TDG) recognizes the intermediate bases 5fC and 5caC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair."], "t": []}], "preferred_name": "chromosomal 5-methylcytosine DNA demethylation, oxidation pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.617122625489202", "identifiers": [{"i": "GO:0030198", "l": "extracellular matrix organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix."], "t": []}], "preferred_name": "extracellular matrix organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0010138", "l": "pyrimidine ribonucleotide salvage", "d": ["The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis."], "t": []}], "preferred_name": "pyrimidine ribonucleotide salvage", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070147", "l": "mitochondrial cysteinyl-tRNA aminoacylation", "d": ["The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA."], "t": []}], "preferred_name": "mitochondrial cysteinyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:1904037", "l": "positive regulation of epithelial cell apoptotic process", "d": ["Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process."], "t": []}], "preferred_name": "positive regulation of epithelial cell apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0003276", "l": "apoptotic process involved in heart valve morphogenesis", "d": ["Any apoptotic process that contributes to the shaping of a heart valve."], "t": []}], "preferred_name": "apoptotic process involved in heart valve morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0036250", "l": "peroxisome transport along microtubule", "d": ["The directed movement of a peroxisome along a microtubule, mediated by motor proteins."], "t": []}], "preferred_name": "peroxisome transport along microtubule", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "60.752038319846697", "identifiers": [{"i": "GO:0051701", "l": "biological process involved in interaction with host", "d": ["An interaction between two organisms living together in more or less intimate association. 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In non-mammalian species, absorption may occur in related structures."], "t": []}], "preferred_name": "renal phosphate ion absorption", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0097114", "l": "NMDA glutamate receptor clustering", "d": ["The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane."], "t": []}], "preferred_name": "NMDA glutamate receptor clustering", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0042984", "l": "regulation of amyloid precursor protein biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta."], "t": []}], "preferred_name": "regulation of amyloid precursor protein biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0006424", "l": "glutamyl-tRNA aminoacylation", "d": ["The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. 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"identifiers": [{"i": "GO:2000166", "l": "negative regulation of planar cell polarity pathway involved in pericardium morphogenesis", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis."], "t": []}], "preferred_name": "negative regulation of planar cell polarity pathway involved in pericardium morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "80.588190044528119", "identifiers": [{"i": "GO:0046485", "l": "ether lipid metabolic process", "d": ["The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol."], "t": []}], "preferred_name": "ether lipid metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021853", "l": "cerebral cortex GABAergic interneuron migration", "d": ["The migration of 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Mating types are the equivalent in microorganisms of the sexes in higher organisms."], "t": []}], "preferred_name": "mating type determination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905551", "l": "negative regulation of protein localization to endoplasmic reticulum", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum."], "t": []}], "preferred_name": "negative regulation of protein localization to endoplasmic reticulum", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.903807027794471", "identifiers": [{"i": "GO:0070482", "l": "response to oxygen levels", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen."], "t": []}], "preferred_name": "response to oxygen levels", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:2000338", "l": "regulation of chemokine (C-X-C motif) ligand 1 production", "d": ["Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production."], "t": []}], "preferred_name": "regulation of chemokine (C-X-C motif) ligand 1 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.576917823386069", "identifiers": [{"i": "GO:0021695", "l": "cerebellar cortex development", "d": ["The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. 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Ligase is the systematic name for any enzyme of EC class 6."], "t": []}], "preferred_name": "regulation of ligase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0034094", "l": "regulation of maintenance of meiotic sister chromatid cohesion", "d": ["Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle."], "t": []}], "preferred_name": "regulation of maintenance of meiotic sister chromatid cohesion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0071952", "l": "conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA", "d": ["The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA."], "t": []}], "preferred_name": "conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031158", "l": "negative regulation of aggregate size involved in sorocarp development", "d": ["Any process that decreases the size of the aggregate formed during sorocarp formation."], "t": []}], "preferred_name": "negative regulation of aggregate size involved in sorocarp development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0098779", "l": "positive regulation of mitophagy in response to mitochondrial depolarization", "d": ["Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization."], "t": []}], "preferred_name": "positive regulation of mitophagy in response to mitochondrial depolarization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090437", "l": "socket cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support."], "t": []}], "preferred_name": "socket cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902989", "l": "meiotic telomere maintenance via semi-conservative replication", "d": ["Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle."], "t": []}], "preferred_name": "meiotic telomere maintenance via semi-conservative replication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904324", "l": "negative regulation of inhibitory G protein-coupled receptor phosphorylation", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation."], "t": []}], "preferred_name": "negative regulation of inhibitory G protein-coupled receptor phosphorylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:2001097", "l": "laminaritriose transport", "d": ["The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."], "t": []}], "preferred_name": "laminaritriose transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018167", "l": "protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine", "d": ["The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine."], "t": []}], "preferred_name": "protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.271528348933202", "identifiers": [{"i": "GO:0048483", "l": "autonomic nervous system development", "d": ["The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. 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This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals."], "t": []}], "preferred_name": "IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061950", "l": "negative regulation of premature acrosome loss", "d": ["Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. 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The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion."], "t": []}], "preferred_name": "glossopharyngeal nerve structural organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0072766", "l": "centromere clustering at the mitotic interphase nuclear envelope", "d": ["The process in which chromatin, or kinetochores are anchored to the nuclear envelope. 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Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. 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[{"i": "GO:0019597", "l": "(R)-mandelate catabolic process to benzoate", "d": ["The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate."], "t": []}], "preferred_name": "(R)-mandelate catabolic process to benzoate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0010421", "l": "hydrogen peroxide-mediated programmed cell death", "d": ["Programmed cell death induced by hydrogen peroxide. 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This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers."], "t": []}], "preferred_name": "myoblast fate specification involved in skeletal muscle regeneration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "72.685545702361054", "identifiers": [{"i": "GO:0051250", "l": "negative regulation of lymphocyte activation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation."], "t": []}], "preferred_name": "negative regulation of lymphocyte activation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0071649", "l": "regulation of chemokine (C-C motif) ligand 5 production", "d": ["Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5."], "t": []}], "preferred_name": "regulation of chemokine (C-C motif) ligand 5 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.051963878740779", "identifiers": [{"i": "GO:0010016", "l": "shoot system morphogenesis", "d": ["The process in which the anatomical structures of the shoot are generated and organized. 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Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. Occurs in non-enveloped prokaryotic viruses."], "t": []}], "preferred_name": "symbiont genome ejection through host cell envelope, short tail mechanism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141081", "l": "symbiont-mediated suppression of host inflammasome-mediated signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or stops an inflammasome-mediated signal transduction pathway in the host organism by interfering with its normal execution. 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This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur."], "t": []}], "preferred_name": "sperm entry", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:1903352", "l": "L-ornithine transmembrane transport", "d": ["The directed movement of L-ornithine across a membrane."], "t": []}], "preferred_name": "L-ornithine transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "79.621676966838109", "identifiers": [{"i": "GO:0051782", "l": "negative regulation of cell division", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of cell division."], "t": []}], "preferred_name": "negative regulation of cell division", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0070393", "l": "teichoic acid catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues."], "t": []}], "preferred_name": "teichoic acid catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061591", "l": "calcium activated galactosylceramide scrambling", "d": ["The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus."], "t": []}], "preferred_name": "calcium activated galactosylceramide scrambling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018026", "l": "peptidyl-lysine monomethylation", "d": ["The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine."], "t": []}], "preferred_name": "peptidyl-lysine monomethylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:0009856", "l": "pollination", "d": ["The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion."], "t": []}], "preferred_name": "pollination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "57.82694644236377", "identifiers": [{"i": "GO:0002460", "l": "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "d": ["An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. 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Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. 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The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella."], "t": []}], "preferred_name": "regulation of cleistothecium development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905860", "l": "positive regulation of heparan sulfate proteoglycan binding", "d": ["Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding."], "t": []}], "preferred_name": "positive regulation of heparan sulfate proteoglycan binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046074", "l": "dTMP catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate."], "t": []}], "preferred_name": "dTMP catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904436", "l": "negative regulation of transferrin receptor binding", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding."], "t": []}], "preferred_name": "negative regulation of transferrin receptor binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:1900909", "l": "negative regulation of olefin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process."], "t": []}], "preferred_name": "negative regulation of olefin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006225", "l": "UDP biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate."], "t": []}], "preferred_name": "UDP biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0009265", "l": "2'-deoxyribonucleotide biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."], "t": []}], "preferred_name": "2'-deoxyribonucleotide biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0050482", "l": "arachidonic acid secretion", "d": ["The controlled release of arachidonic acid from a cell or a tissue."], "t": []}], "preferred_name": "arachidonic acid secretion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042714", "l": "dosage compensation complex assembly", "d": ["The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes."], "t": []}], "preferred_name": "dosage compensation complex assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "66.92256712576048", "identifiers": [{"i": "GO:0071478", "l": "cellular response to radiation", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. 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The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex."], "t": []}], "preferred_name": "metanephric cortical collecting duct development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0032887", "l": "regulation of spindle elongation", "d": ["Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle."], "t": []}], "preferred_name": "regulation of spindle elongation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1904133", "l": "regulation of convergent extension involved in rhombomere morphogenesis", "d": ["Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis."], "t": []}], "preferred_name": "regulation of convergent extension involved in rhombomere morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0001897", "l": "symbiont-mediated cytolysis of host cell", "d": ["A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. 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The bud elongates and branches to give rise to the ureter and kidney collecting tubules."], "t": []}], "preferred_name": "regulation of branching involved in ureteric bud morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0120198", "l": "positive regulation of imaginal disc-derived wing size", "d": ["Any process that increases the size of an imaginal disc-derived wing."], "t": []}], "preferred_name": "positive regulation of imaginal disc-derived wing size", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.007204735288752", "identifiers": [{"i": "GO:0034440", "l": "lipid oxidation", "d": ["The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen."], "t": []}], "preferred_name": "lipid oxidation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070583", "l": "spore membrane bending pathway", "d": ["The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore."], "t": []}], "preferred_name": "spore membrane bending pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051066", "l": "dihydrobiopterin metabolic process", "d": ["The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions."], "t": []}], "preferred_name": "dihydrobiopterin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0097711", "l": "ciliary basal body-plasma membrane docking", "d": ["The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. 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The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane."], "t": []}], "preferred_name": "ciliary basal body-plasma membrane docking", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903885", "l": "negative regulation of chemokine (C-C motif) ligand 20 production", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production."], "t": []}], "preferred_name": "negative regulation of chemokine (C-C motif) ligand 20 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141168", "l": "chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway", "d": ["An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. 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The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)."], "t": []}], "preferred_name": "nucleotide-excision repair", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905597", "l": "positive regulation of low-density lipoprotein particle receptor binding", "d": ["Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding."], "t": []}], "preferred_name": "positive regulation of low-density lipoprotein particle receptor binding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.617749940116425", "identifiers": [{"i": "GO:0007442", "l": "hindgut morphogenesis", "d": ["The process in which the anatomical structures of the hindgut are generated and organized."], "t": []}], "preferred_name": "hindgut morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0048382", "l": "mesendoderm development", "d": ["The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. 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The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)."], "t": []}], "preferred_name": "hindbrain development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0048899", "l": "anterior lateral line development", "d": ["The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. 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Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate."], "t": []}], "preferred_name": "visceral motor neuron differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0051152", "l": "positive regulation of smooth muscle cell differentiation", "d": ["Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation."], "t": []}], "preferred_name": "positive regulation of smooth muscle cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900461", "l": "positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter", "d": ["Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter."], "t": []}], "preferred_name": "positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0007319", "l": "negative regulation of oskar mRNA translation", "d": ["Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein."], "t": []}], "preferred_name": "negative regulation of oskar mRNA translation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0018871", "l": "1-aminocyclopropane-1-carboxylate metabolic process", "d": ["The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. 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The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop."], "t": []}], "preferred_name": "positive regulation of conidiophore stalk development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0014034", "l": "neural crest cell fate commitment", "d": ["The process in which a cell becomes committed to become a neural crest cell."], "t": []}], "preferred_name": "neural crest cell fate commitment", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0044277", "l": "cell wall disassembly", "d": ["A process that results in the breakdown of the cell wall."], "t": []}], "preferred_name": "cell wall disassembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062227", "l": "positive regulation of adult somatic muscle development", 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904070", "l": "ascaroside biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of ascaroside."], "t": []}], "preferred_name": "ascaroside biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0060310", "l": "regulation of elastin catabolic process", "d": ["Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin."], "t": []}], "preferred_name": "regulation of elastin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0160018", "l": "positive regulation of platelet rolling", "d": ["Any process that increases the rate, frequency, or extent of platelet rolling."], "t": []}], "preferred_name": "positive regulation of platelet rolling", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.290860735708023", "identifiers": [{"i": "GO:0090136", "l": "epithelial cell-cell adhesion", "d": ["The attachment of an epithelial cell to another epithelial cell via adhesion molecules."], "t": []}], "preferred_name": "epithelial cell-cell adhesion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1902347", "l": "response to strigolactone", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus."], "t": []}], "preferred_name": "response to strigolactone", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0009861", "l": "jasmonic acid and ethylene-dependent systemic resistance", "d": ["The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to 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"identifiers": [{"i": "GO:0051591", "l": "response to cAMP", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus."], "t": []}], "preferred_name": "response to cAMP", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0048923", "l": "posterior lateral line neuromast hair cell differentiation", "d": ["The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. 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"100", "identifiers": [{"i": "GO:0051296", "l": "establishment of meiotic spindle orientation", "d": ["Any process that set the alignment of meiotic spindle relative to other cellular structures."], "t": []}], "preferred_name": "establishment of meiotic spindle orientation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046290", "l": "isoflavonoid phytoalexin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection."], "t": []}], "preferred_name": "isoflavonoid phytoalexin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0106119", "l": "negative regulation of sterol biosynthetic process", "d": ["Any process that stops, prevents or reduces the 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The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain."], "t": []}], "preferred_name": "Bolwig's organ development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0043077", "l": "initiation of acetate catabolic process", "d": ["The activation of the chemical reactions and pathways resulting in the breakdown of acetate."], "t": []}], "preferred_name": "initiation of acetate catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0009962", "l": "regulation of flavonoid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids."], "t": []}], "preferred_name": "regulation of flavonoid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "82.146630911483399", "identifiers": [{"i": "GO:0050746", "l": "regulation of lipoprotein metabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids."], "t": []}], "preferred_name": "regulation of lipoprotein metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0034033", "l": "purine nucleoside bisphosphate biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar."], "t": []}], "preferred_name": "purine nucleoside bisphosphate biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018003", "l": "peptidyl-lysine N6-acetylation", "d": ["The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine."], "t": []}], "preferred_name": "peptidyl-lysine N6-acetylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990643", "l": "cellular response to granulocyte colony-stimulating factor", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus."], "t": []}], "preferred_name": "cellular response to granulocyte colony-stimulating factor", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0099533", "l": "positive regulation of presynaptic cytosolic calcium concentration", "d": ["Any process that increases the concentration of calcium ions in the presynaptic cytosol."], "t": []}], "preferred_name": "positive regulation of presynaptic cytosolic calcium concentration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0072090", "l": "mesenchymal stem cell proliferation involved in nephron morphogenesis", "d": ["The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron."], "t": []}], "preferred_name": "mesenchymal stem cell proliferation involved in nephron morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021612", "l": "facial nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the facial nerve. 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"preferred_name": "vitamin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060239", "l": "positive regulation of signal transduction involved in conjugation with cellular fusion", "d": ["Any process that increases the rate, frequency or extent of signal transduction involved in conjugation with cellular fusion."], "t": []}], "preferred_name": "positive regulation of signal transduction involved in conjugation with cellular fusion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032716", "l": "negative regulation of interleukin-7 production", "d": ["Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production."], "t": []}], "preferred_name": "negative regulation of interleukin-7 production", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016348", "l": "imaginal disc-derived leg joint 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An example of this is found in Drosophila melanogaster."], "t": []}], "preferred_name": "imaginal disc-derived leg joint morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0098710", "l": "guanine import across plasma membrane", "d": ["The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol."], "t": []}], "preferred_name": "guanine import across plasma membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051680", "l": "6-alpha-maltosylglucose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose."], "t": []}], "preferred_name": "6-alpha-maltosylglucose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.778909590344668", "identifiers": [{"i": "GO:0051170", "l": "import into nucleus", "d": ["The directed movement of substances into the nucleus."], "t": []}], "preferred_name": "import into nucleus", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0051123", "l": "RNA polymerase II preinitiation complex assembly", "d": ["The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which may include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH complexes). The PIC engages RNA polymerase II on its DNA template strand and sparks polymerization of the first few RNA nucleotides of the nascent transcript, of which 8 are base-paired with the DNA template within a DNA bubble. PIC assembly may result in a pause step, which marks the end of the PIC assembly and may be followed by promoter clearance (exact synonym: promoter escape). For RNA polymerase II PIC assembly is preceded by the formation of a nucleosome-free region that allows the transcription machinery to access the promoter DNA."], "t": []}], "preferred_name": "RNA polymerase II preinitiation complex assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "71.028704465244275", "identifiers": [{"i": "GO:1990542", "l": "mitochondrial transmembrane transport", "d": ["The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion."], "t": []}], "preferred_name": "mitochondrial transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0100001", "l": "regulation of skeletal muscle contraction by action potential", "d": ["Any action potential process that regulates skeletal muscle contraction."], "t": []}], "preferred_name": "regulation of skeletal muscle contraction by action potential", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.517524484334686", "identifiers": [{"i": "GO:0045185", "l": "maintenance of protein location", "d": ["Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away."], "t": []}], "preferred_name": "maintenance of protein location", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090292", "l": "nuclear matrix anchoring at nuclear membrane", "d": ["The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane."], "t": []}], "preferred_name": "nuclear matrix anchoring at nuclear membrane", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0051262", "l": "protein tetramerization", "d": ["The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits."], "t": []}], "preferred_name": "protein tetramerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0060435", "l": "bronchiole development", "d": ["The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi."], "t": []}], "preferred_name": "bronchiole development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.721147647610692", "identifiers": [{"i": "GO:0006074", "l": "(1->3)-beta-D-glucan metabolic process", "d": ["The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds."], "t": []}], "preferred_name": "(1->3)-beta-D-glucan metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0031221", "l": "arabinan metabolic process", "d": ["The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues."], "t": []}], "preferred_name": "arabinan metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0051966", "l": "regulation of synaptic transmission, glutamatergic", "d": ["Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate."], "t": []}], "preferred_name": "regulation of synaptic transmission, glutamatergic", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0090721", "l": "primary adaptive immune response involving T cells and B cells", "d": ["An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system."], "t": []}], "preferred_name": "primary adaptive immune response involving T cells and B cells", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902078", "l": "positive regulation of lateral motor column neuron migration", "d": ["Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration."], "t": []}], "preferred_name": "positive regulation of lateral motor column neuron migration", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0141123", "l": "dermonecrosis in another organism", "d": ["The disruption of the skin of another organism, leading to damage or temporary subversion of the skin."], "t": []}], "preferred_name": "dermonecrosis in another organism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060672", "l": "epithelial cell morphogenesis involved in placental branching", "d": ["The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta."], "t": []}], "preferred_name": "epithelial cell morphogenesis involved in placental branching", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0010690", "l": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress", "d": ["Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis."], "t": []}], "preferred_name": "negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021672", "l": "rhombomere 7 structural organization", "d": ["The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order."], "t": []}], "preferred_name": "rhombomere 7 structural organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0007339", "l": "binding of sperm to zona pellucida", "d": ["The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. 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In a single-pass circulatory system blood passes once through the heart to supply the body once."], "t": []}], "preferred_name": "ventral aorta morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1903860", "l": "negative regulation of dendrite extension", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension."], "t": []}], "preferred_name": "negative regulation of dendrite extension", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.191390054935425", "identifiers": [{"i": "GO:0006878", "l": "intracellular copper ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell."], "t": []}], "preferred_name": "intracellular copper ion homeostasis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0070857", "l": "regulation of bile acid biosynthetic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids."], "t": []}], "preferred_name": "regulation of bile acid biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0006433", "l": "prolyl-tRNA aminoacylation", "d": ["The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. 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K6-linked ubiquitination is involved in DNA repair."], "t": []}], "preferred_name": "protein K6-linked ubiquitination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904843", "l": "cellular response to nitroglycerin", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus."], "t": []}], "preferred_name": "cellular response to nitroglycerin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:1900969", "l": "negative regulation of sarcinapterin metabolic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process."], "t": []}], "preferred_name": "negative regulation of sarcinapterin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0048807", "l": "female genitalia morphogenesis", "d": ["The process in which the anatomical structures of female genitalia are generated and organized."], "t": []}], "preferred_name": "female genitalia morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "78.778909590344668", "identifiers": [{"i": "GO:0002834", "l": "regulation of response to tumor cell", "d": ["Any process that modulates the frequency, rate, or extent of a response to tumor cell."], "t": []}], "preferred_name": "regulation of response to tumor cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.090052188295473", "identifiers": [{"i": "GO:0006564", "l": "L-serine biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid."], "t": []}], "preferred_name": "L-serine biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0097119", "l": "postsynaptic density protein 95 clustering", "d": ["The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. 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Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. 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In addition to CG sites, plants also methylate cytosines within CHH and CNG sequences."], "t": []}], "preferred_name": "chromosomal 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.560648264911265", "identifiers": [{"i": "GO:1901661", "l": "quinone metabolic process", "d": ["The chemical reactions and pathways involving quinone."], "t": []}], "preferred_name": "quinone metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "81.321467557226839", "identifiers": [{"i": "GO:1905331", "l": "negative regulation of morphogenesis of an epithelium", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium."], "t": []}], "preferred_name": "negative regulation of morphogenesis of an epithelium", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051614", "l": "inhibition of serotonin uptake", "d": ["Any process that prevents the activation of the directed movement of serotonin into a cell."], "t": []}], "preferred_name": "inhibition of serotonin uptake", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0018429", "l": "copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide", "d": ["The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide."], "t": []}], "preferred_name": "copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0051594", "l": "detection of glucose", "d": ["The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal."], "t": []}], "preferred_name": "detection of glucose", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903850", "l": "regulation of cristae formation", "d": ["Any process that modulates the frequency, rate or extent of cristae formation."], "t": []}], "preferred_name": "regulation of cristae formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045325", "l": "peptidyl-tryptophan hydroxylation", "d": ["The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan."], "t": []}], "preferred_name": "peptidyl-tryptophan hydroxylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0006756", "l": "AMP phosphorylation", "d": ["The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. 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Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses."], "t": []}], "preferred_name": "phthalate metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051894", "l": "positive regulation of focal adhesion assembly", "d": ["Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions."], "t": []}], "preferred_name": "positive regulation of focal adhesion assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:1900597", "l": "demethylkotanin metabolic process", "d": ["The chemical reactions and pathways involving demethylkotanin."], "t": []}], "preferred_name": "demethylkotanin metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904840", "l": "positive regulation of male germ-line stem cell asymmetric division", "d": ["Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division."], "t": []}], "preferred_name": "positive regulation of male germ-line stem cell asymmetric division", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902173", "l": "negative regulation of keratinocyte apoptotic process", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process."], "t": []}], "preferred_name": "negative regulation of keratinocyte apoptotic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1902900", "l": "gut granule assembly", "d": ["The aggregation, arrangement and bonding together of a set of components to form a gut granule."], "t": []}], "preferred_name": "gut granule assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0010813", "l": "neuropeptide catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of neuropeptides. 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Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport."], "t": []}], "preferred_name": "mesonephric glomerular parietal epithelial cell development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905959", "l": "positive regulation of cellular response to alcohol", "d": ["Any process that activates or increases the frequency, rate or extent of cellular response to alcohol."], "t": []}], "preferred_name": "positive regulation of cellular response to alcohol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0071280", "l": "cellular response to copper ion", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus."], "t": []}], "preferred_name": "cellular response to copper ion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060982", "l": "coronary artery morphogenesis", "d": ["The process in which the anatomical structures of coronary arteries are generated and organized. 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The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules."], "t": []}], "preferred_name": "tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "73.580844850107752", "identifiers": [{"i": "GO:0090529", "l": "cell septum assembly", "d": ["The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. 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When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. 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An example of this process is found in Mus musculus."], "t": []}], "preferred_name": "enucleate erythrocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904211", "l": "membrane protein proteolysis involved in retrograde protein transport, ER to cytosol", "d": ["Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol."], "t": []}], "preferred_name": "membrane protein proteolysis involved in retrograde protein transport, ER to cytosol", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0061205", "l": "paramesonephric duct development", "d": ["The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. 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This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. 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Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals."], "t": []}], "preferred_name": "dibenzofuran metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0062087", "l": "positive regulation of vein smooth muscle contraction", "d": ["Any process that increases the frequency, rate or extent of vein smooth muscle contraction."], "t": []}], "preferred_name": "positive regulation of vein smooth muscle contraction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0071896", "l": "protein localization to adherens junction", "d": ["Any process in which a protein is transported to, and/or maintained at the adherens junction."], "t": []}], "preferred_name": "protein localization to adherens junction", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.517524484334686", "identifiers": [{"i": "GO:0009948", "l": "anterior/posterior axis specification", "d": ["The establishment, maintenance and elaboration of the anterior/posterior axis. 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The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "detection of symbiont", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1902974", "l": "meiotic DNA replication initiation", "d": ["Any DNA replication initiation involved in meiotic cell cycle DNA replication."], "t": []}], "preferred_name": "meiotic DNA replication initiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905786", "l": "positive regulation of anaphase-promoting complex-dependent catabolic process", "d": ["Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process."], "t": []}], "preferred_name": "positive regulation of anaphase-promoting complex-dependent catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.819741707074996", "identifiers": [{"i": "GO:0061774", "l": "cohesin unloading", "d": ["Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA."], "t": []}], "preferred_name": "cohesin unloading", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0021624", "l": "oculomotor nerve structural organization", "d": ["The process that contributes to the act of creating the structural organization of the oculomotor nerve. 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This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. 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It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes."], "t": []}], "preferred_name": "phosphatidylethanolamine metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "74.903807027794471", "identifiers": [{"i": "GO:0009812", "l": "flavonoid metabolic process", "d": ["The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins."], "t": []}], "preferred_name": "flavonoid metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900648", "l": "positive regulation of chanoclavine-I aldehyde biosynthetic process", "d": ["Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process."], "t": []}], "preferred_name": "positive regulation of chanoclavine-I aldehyde biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.751754469129523", "identifiers": [{"i": "GO:0072234", "l": "metanephric nephron tubule development", "d": ["The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. 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In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events."], "t": []}], "preferred_name": "endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0009231", "l": "riboflavin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)."], "t": []}], "preferred_name": "riboflavin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0048855", "l": "adenohypophysis morphogenesis", "d": ["The process in which the anatomical structures of the adenohypophysis are generated and organized. 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Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. 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This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates."], "t": []}], "preferred_name": "rhombomere formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1903286", "l": "regulation of potassium ion import", "d": ["Any process that modulates the frequency, rate or extent of potassium ion import."], "t": []}], "preferred_name": "regulation of potassium ion import", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0071494", "l": "cellular response to UV-C", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. 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A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases."], "t": []}], "preferred_name": "lysosome organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045035", "l": "sensory organ precursor cell division", "d": ["The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. 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STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes."], "t": []}], "preferred_name": "symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0016243", "l": "regulation of autophagosome size", "d": ["Any process that modulates the size of the autophagosome."], "t": []}], "preferred_name": "regulation of autophagosome size", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0039635", "l": "suppression by virus of host peptidoglycan biosynthetic process", "d": ["Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. 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"biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1905524", "l": "negative regulation of protein autoubiquitination", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination."], "t": []}], "preferred_name": "negative regulation of protein autoubiquitination", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:1900596", "l": "(+)-kotanin biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of (+)-kotanin."], "t": []}], "preferred_name": "(+)-kotanin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0045607", "l": "regulation of inner ear auditory receptor cell differentiation", "d": ["Any process that modulates the frequency, rate or extent of auditory hair cell differentiation."], "t": []}], "preferred_name": "regulation of inner ear auditory 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The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule."], "t": []}], "preferred_name": "metanephric proximal convoluted tubule development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106213", "l": "kinetochore disassembly involved in meiotic chromosome organization", "d": ["The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I."], "t": []}], "preferred_name": "kinetochore disassembly involved in meiotic chromosome organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0000387", "l": "spliceosomal snRNP assembly", "d": ["The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome."], "t": []}], "preferred_name": "spliceosomal snRNP assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.51435223262213", "identifiers": [{"i": "GO:0060193", "l": "positive regulation of lipase activity", "d": ["Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid."], "t": []}], "preferred_name": "positive regulation of lipase activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:1900591", "l": "violaceol II metabolic process", "d": ["The chemical reactions and pathways involving violaceol II."], "t": []}], "preferred_name": "violaceol II metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0021566", "l": "hypoglossal nerve development", "d": ["The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. 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The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability."], "t": []}], "preferred_name": "kinin cascade", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0070810", "l": "positive regulation of Hulle cell development", "d": ["Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. 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Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli."], "t": []}], "preferred_name": "response to pain", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0006883", "l": "intracellular sodium ion homeostasis", "d": ["A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell."], "t": []}], "preferred_name": "intracellular sodium ion homeostasis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060735", "l": "regulation of eIF2 alpha phosphorylation by dsRNA", "d": ["Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA."], "t": []}], "preferred_name": "regulation of eIF2 alpha phosphorylation by dsRNA", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0150032", "l": "positive regulation of protein localization to lysosome", "d": ["Any process that activates or increases the frequency, rate or extent of protein localization to lysosome."], "t": []}], "preferred_name": "positive regulation of protein localization to lysosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0072289", "l": "metanephric nephron tubule formation", "d": ["The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. 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The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand."], "t": []}], "preferred_name": "negative regulation of growth hormone receptor signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.43028691190267", "identifiers": [{"i": "GO:0061182", "l": "negative regulation of chondrocyte development", "d": ["Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate."], "t": []}], "preferred_name": "negative regulation of chondrocyte development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0046150", "l": "melanin catabolic process", "d": ["The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom."], "t": []}], "preferred_name": "melanin catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0000372", "l": "Group I intron splicing", "d": ["The splicing of Group I introns. 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The intron is excised as a linear piece (though it may subsequently circularize)."], "t": []}], "preferred_name": "Group I intron splicing", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0033472", "l": "GDP-L-galactose biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate."], "t": []}], "preferred_name": "GDP-L-galactose biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0050947", "l": "negative regulation of early stripe melanocyte differentiation", "d": ["Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation."], "t": []}], "preferred_name": "negative regulation of early stripe melanocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "67.909793895370484", "identifiers": [{"i": "GO:0042440", "l": "pigment metabolic process", "d": ["The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin."], "t": []}], "preferred_name": "pigment metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.860573823805353", "identifiers": [{"i": "GO:0098914", "l": "membrane repolarization during atrial cardiac muscle cell action potential", "d": ["The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential."], "t": []}], "preferred_name": "membrane repolarization during atrial cardiac muscle cell action potential", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904172", "l": "positive regulation of bleb assembly", "d": ["Any process that activates or increases the frequency, rate or extent of bleb assembly."], "t": []}], "preferred_name": "positive regulation of bleb assembly", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1990786", "l": "cellular response to dsDNA", "d": ["Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus."], "t": []}], "preferred_name": "cellular response to dsDNA", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0052322", "l": "positive regulation of phytoalexin biosynthetic process", "d": ["Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins."], "t": []}], "preferred_name": "positive regulation of phytoalexin biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0007430", "l": "terminal branching, open tracheal system", "d": ["Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster."], "t": []}], "preferred_name": "terminal branching, open tracheal system", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0080154", "l": "regulation of fertilization", "d": ["Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. 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The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA."], "t": []}], "preferred_name": "lysyl-tRNA aminoacylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "83.090052188295473", "identifiers": [{"i": "GO:0048439", "l": "flower morphogenesis", "d": ["The process in which the anatomical structures of the flower are generated and organized."], "t": []}], "preferred_name": "flower morphogenesis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0042250", "l": "maintenance of polarity of embryonic epithelium", "d": ["The maintenance of an established polarized embryonic epithelial sheet."], "t": []}], "preferred_name": "maintenance of polarity of embryonic epithelium", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045958", "l": "positive regulation of complement activation, alternative pathway", "d": ["Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway."], "t": []}], "preferred_name": "positive regulation of complement activation, alternative pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0006957", "l": "complement activation, alternative pathway", "d": ["Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes."], "t": []}], "preferred_name": "complement activation, alternative pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:1900309", "l": "regulation of maltoheptaose metabolic process", "d": ["Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process."], "t": []}], "preferred_name": "regulation of maltoheptaose metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0098039", "l": "replicative DNA transposition", "d": ["Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. 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Also found in plants."], "t": []}], "preferred_name": "progesterone catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.187463028213742", "identifiers": [{"i": "GO:0015771", "l": "trehalose transport", "d": ["The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. 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The G0 to G1 transition is accompanied by many changes in the program of gene expression."], "t": []}], "preferred_name": "G0 to G1 transition", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.757176116311072", "identifiers": [{"i": "GO:0018915", "l": "ethylbenzene metabolic process", "d": ["The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels."], "t": []}], "preferred_name": "ethylbenzene metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "89.389454795172327", "identifiers": [{"i": "GO:0046036", "l": "CTP metabolic process", "d": ["The chemical reactions and pathways involving CTP, cytidine triphosphate."], "t": []}], "preferred_name": "CTP metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.171193469738924", "identifiers": [{"i": "GO:0010818", "l": "T cell chemotaxis", "d": ["The directed movement of a T cell in response to an external stimulus. 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